3S9UA

Bacillus anthracis dihydrofolate reductase bound to propargyl-linked tmp analog, ucp120j
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
165
structure length
165
Chain Sequence
HHHMRVSFMVAMDENRVIGKDNNLPWRLPSELQYVKKTTMGHPLIMGRKNYEAIGRPLPGRRNIIVTRNEGYHVEGCEVAHSVEEVFELCKNEEEIFIFGGAQIYDLFLPYVDKLYITKIHHAFEGDTFFPEMDMTNWKEVFVEKGLTDEKNPYTYYYHVYEKQQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Activity Studies of Heterocyclic Propargyl-linked TMP Analogs Targeting Bacillus anthracis Dihydrofolate Reductase
rcsb
molecule tags Oxidoreductase
source organism Bacillus anthracis
molecule keywords Dihydrofolate reductase
total genus 43
structure length 165
sequence length 165
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2011-06-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3s9uA00
3EEMA 4QJZD 1IA4A 1MVSA 4TU5X 4M6JA 3DL6A 5HT4A 3SH2A 1LY3A 2HQPA 1IA3A 4KY4A 1RX6A 3IX9A 3ZPGA 3DAUA 1DG7A 2FZIA 4KEBA 3M09A 3KJRA 3DRCA 1CZ3A 1ZDRA 3FL8A 1DLRA 4IXGX 2C2TA 2AZNA 2ANQA 2W3WA 3FQZA 1DF7A 3EIGA 3I3RA 4M7UA 4G8ZX 2G6VA 3NZ9X 3FYVX 4KM0A 2W3AA 5HVEA 3FRBX 4ELHA 2W9GA 4ELFA 4QI9A 4PSSA 1DRHA 5ECXA 4ELBA 3EEKA 3SA2A 3FQVA 3TQ8A 1RF7A 3JWMA 1PD8A 1SEJA 4H97A 3QLZA 4CD2A 4HOGA 3SRUX 2FZJA 3QGTA 1RC4A 1DHFA 4Q0EA 1PDBA 1RA8A 3KJSA 4KD7A 4QLGA 4DP3A 4OR7A 3SA1A 3F0XX 3NXYA 3UM5A 3EX8A 3E0BA 3F0SX 1DRAA 3F0VX 1AO8A 1RX4A 3SR5X 4DFRA 1IA2A 1OHKA 3F0BX 4P3QA 4KM2A 5JA3A 1RX9A 5CC9A 3IA4A 3TQ9A 3SRQX 4ELGA 2D5NA 3QLYA 4Q0DA 1DISA 4XT6A 1CD2A 2ZZAA 3N0HA 3GHWA 1JOMA 3FQ0A 3UM8A 1PD9A 3F0UX 2W9HA 3K47A 3DGAA 5U27A 3SQYX 1DYRA 2B3ZA 3FY8X 4Q67A 1DHIA 4OSGA 1RA3A 2QK8A 3FRAX 1DREA 4KYAA 3SRSX 3QLWA 4IXFX 1DRBA 3NZAX 3S9UA 3FQCA 3QLSA 3JW3A 1DDSA 3NRRA 4IXED 5U26A 4XT4A 3GHCA 4X5FA 5ECCA 1DR6A 2W9SA 1RG7A 3TQBA 1RH3A 5HPBA 4XE6X 1MVTA 1DR2A 1DYHA 3JSUA 1HFRA 3QLRA 5CCCA 3EEJA 4H96A 1DIUA 1E26A 5HSRA 4FGHA 3KFYA 3NXOA 2GD9A 3I8AX 2LF1A 3INVA 4EIZA 3DATA 3VCOA 1DR7A 2INQA 3S3VA 3UM6A 4KJLA 1M7AA 5FDAA 1VJ3A 3FS6A 3LG4A 1DR4A 3S7AA 1S3WA 4KY8A 4KJJA 1DR5A 4X5GA 3FY9X 1DR1A 2FZHA 3QYLA 3K74A 1DDRA 3Q1HA 4XT5A 3F8ZA 4H95A 3QG2A 1RX1A 2HM9A 3JVXA 4RGCA 3M08A 4ECKA 1KLKA 4Q6AA 3QYOA 5JG0X 1IA1A 3NZ6X 1KMSA 3HJ3A 1JUVA 1DYJA 3GHVA 4M6LA 3NXTA 3RG9A 3JWCA 4G3MA 4HA7A 4P68A 2W9TA 3CLBA 3NTZA 3HBBA 1RA9A 1DG8A 2DHFA 4HA9A 6DFRA 4I13A 8DFRA 2ITHA 1KMVA 4PDJA 3K45A 3KGYA 3FRFX 4H98A 4QHVA 4DPDA 2JYBA 1RA1A 3FYWX 3NU0A 4M6KA 3CL9A 2D0KA 1RX2A 2O7PA 4KBNA 2BLCA 4G95A 1DR3A 3GI2A 1DYIA 3NXXA 2W3BA 4KFJA 4EILA 3EELA 1S3VA 1RD7A 3F91A 2CIGA 3DL5A 1DHJA 2CD2A 2KGKA 1RX5A 2W3MA 4ELEA 1RX3A 1HFPA 2DRCA 4HOEA 3QFXA 1JOLA 4KNEA 2C2SA 3JWFA 2BLAA 1DG5A 2P4GA 3FREX 2HXVA 3SAIA 1RX7A 1BZFA 1YHOA 3FRDX 1S3UA 1M78A 3SRRX 4FHBA 1AI9A 5HI6A 1RE7A 4X5IA 3NZCX 3IA5A 4LAEX 1TDRA 5HUIA 2BL9A 4P3RA 1LUDA 4XT7A 3NZBX 3NZDA 5HF2X 4PTHA 2W3VA 1AOEA 3NXVA 5HQYA 1S3YA 3TQAA 4HOFA 4DPHA 1DRFA 5HT5A 5HSUA 1RB2A 1LY4A 1VDRA 5DXVA 1BOZA 7DFRA 1M79A 2ANOA 3L3RA 3R33A 3FQOA 3ZPCA 1RX8A 4X5HA 1J3IA 2XW7A 3IRNA 3JWKA 4X5JA 3GYFA 1QZFA 1DAJA 3IRMA 5E8QA 4FGGA 5DFRA 1U71A 4QLEA 5HVBA 3QL0A 4PSYA 1J3KA 3QLXA 1DLSA 4KL9A 4KAKA 2L28A 4NX6A 3DG8A 3IROA 3SRWX 4PTJA 4EJ1A 4KLXA 4DDRA 3FL9A 3TD8A 1OHJA 4XECX 3DFRA 1U70A 4M7VA 5EAJA 3RO9A 3CD2A 3JTWA 5HF0X 4QLFA 3D84X 2H2QA 3ROAA 3D80A 4P66A 2BLBA 4XT8A 3NXRA 3OAFA 1RA2A 4EIGA 1RB3A 3K2HA 4LEKX 3CSEA 3SGYA 4XRBA 1D1GA 1HFQA 3F0QX 4GH8A 3JW5A 4QJCA 4PSTA 5HQZA 4LAHX 3F8YA 2OIPA 4I1NA 2OBCA 4M2XA 3OCHA 3KY8A 3QL3A 4KJKA 3FQFA 1J3JA 4NX7A 4LAGX 1U72A
chains in the Genus database with same CATH superfamily
3EEMA 4QJZD 1IA4A 1MVSA 4TU5X 4M6JA 3DL6A 5HT4A 3SH2A 1LY3A 2HQPA 1IA3A 4KY4A 1RX6A 3IX9A 3ZPGA 3DAUA 1DG7A 2FZIA 4KEBA 3M09A 3KJRA 3DRCA 1CZ3A 1ZDRA 3FL8A 1DLRA 4IXGX 2C2TA 2AZNA 2ANQA 2W3WA 3FQZA 1DF7A 3EIGA 3I3RA 4M7UA 4G8ZX 2G6VA 3NZ9X 3FYVX 4KM0A 2W3AA 5HVEA 3FRBX 4ELHA 2W9GA 4ELFA 4QI9A 4PSSA 1DRHA 5ECXA 4ELBA 3EEKA 3SA2A 3FQVA 3TQ8A 1RF7A 3JWMA 1PD8A 1SEJA 4H97A 3QLZA 4CD2A 4HOGA 3SRUX 2FZJA 3QGTA 1RC4A 1DHFA 4Q0EA 1PDBA 1RA8A 3KJSA 4KD7A 4QLGA 4DP3A 4OR7A 3SA1A 3F0XX 3NXYA 3UM5A 3EX8A 3E0BA 3F0SX 1DRAA 3F0VX 1AO8A 1RX4A 3SR5X 4DFRA 1IA2A 1OHKA 3F0BX 4P3QA 4KM2A 5JA3A 1RX9A 5CC9A 3IA4A 3TQ9A 3SRQX 4ELGA 2D5NA 3QLYA 4Q0DA 1DISA 4XT6A 1CD2A 2ZZAA 3N0HA 3GHWA 1JOMA 3FQ0A 3UM8A 1PD9A 3F0UX 2W9HA 3K47A 3DGAA 5U27A 3SQYX 1DYRA 2B3ZA 3FY8X 4Q67A 1DHIA 4OSGA 1RA3A 2QK8A 3FRAX 1DREA 4KYAA 3SRSX 3QLWA 4IXFX 1DRBA 3NZAX 3S9UA 3FQCA 3QLSA 3JW3A 1DDSA 3NRRA 4IXED 5U26A 4XT4A 3GHCA 4X5FA 5ECCA 1DR6A 2W9SA 1RG7A 3TQBA 1RH3A 5HPBA 4XE6X 1MVTA 1DR2A 1DYHA 3JSUA 1HFRA 3QLRA 5CCCA 3EEJA 4H96A 1DIUA 1E26A 5HSRA 4FGHA 3KFYA 3NXOA 2GD9A 3I8AX 2LF1A 3INVA 4EIZA 3DATA 3VCOA 1DR7A 2INQA 3S3VA 3UM6A 4KJLA 1M7AA 5FDAA 1VJ3A 3FS6A 3LG4A 1DR4A 3S7AA 1S3WA 4KY8A 4KJJA 1DR5A 4X5GA 3FY9X 1DR1A 2FZHA 3QYLA 3K74A 1DDRA 3Q1HA 4XT5A 3F8ZA 4H95A 3QG2A 1RX1A 2HM9A 3JVXA 4RGCA 3M08A 4ECKA 1KLKA 4Q6AA 3QYOA 5JG0X 1IA1A 3NZ6X 1KMSA 3HJ3A 1JUVA 1DYJA 3GHVA 4M6LA 3NXTA 3RG9A 3JWCA 4G3MA 4HA7A 4P68A 2W9TA 3CLBA 3NTZA 3HBBA 1RA9A 1DG8A 2DHFA 4HA9A 6DFRA 4I13A 8DFRA 2ITHA 1KMVA 4PDJA 3K45A 3KGYA 3FRFX 4H98A 4QHVA 4DPDA 2JYBA 1RA1A 3FYWX 3NU0A 4M6KA 3CL9A 2D0KA 1RX2A 2O7PA 4KBNA 2BLCA 4G95A 1DR3A 3GI2A 1DYIA 3NXXA 2W3BA 4KFJA 4EILA 3EELA 1S3VA 1RD7A 3F91A 2CIGA 3DL5A 1DHJA 2CD2A 2KGKA 1RX5A 2W3MA 4ELEA 1RX3A 1HFPA 2DRCA 4HOEA 3QFXA 1JOLA 4KNEA 2C2SA 3JWFA 2BLAA 1DG5A 2P4GA 3FREX 2HXVA 3SAIA 1RX7A 1BZFA 1YHOA 3FRDX 1S3UA 1M78A 3SRRX 4FHBA 1AI9A 5HI6A 1RE7A 4X5IA 3NZCX 3IA5A 4LAEX 1TDRA 5HUIA 2BL9A 4P3RA 1LUDA 4XT7A 3NZBX 3NZDA 5HF2X 4PTHA 2W3VA 1AOEA 3NXVA 5HQYA 1S3YA 3TQAA 4HOFA 4DPHA 1DRFA 5HT5A 5HSUA 1RB2A 1LY4A 1VDRA 5DXVA 1BOZA 7DFRA 1M79A 2ANOA 3L3RA 3R33A 3FQOA 3ZPCA 1RX8A 4X5HA 1J3IA 2XW7A 3IRNA 3JWKA 4X5JA 3GYFA 1QZFA 1DAJA 3IRMA 5E8QA 4FGGA 5DFRA 1U71A 4QLEA 5HVBA 3QL0A 4PSYA 1J3KA 3QLXA 1DLSA 4KL9A 4KAKA 2L28A 4NX6A 3DG8A 3IROA 3SRWX 4PTJA 4EJ1A 4KLXA 4DDRA 3FL9A 3TD8A 1OHJA 4XECX 3DFRA 1U70A 4M7VA 5EAJA 3RO9A 3CD2A 3JTWA 5HF0X 4QLFA 3D84X 2H2QA 3ROAA 3D80A 4P66A 2BLBA 4XT8A 3NXRA 3OAFA 1RA2A 4EIGA 1RB3A 3K2HA 4LEKX 3CSEA 3SGYA 4XRBA 1D1GA 1HFQA 3F0QX 4GH8A 3JW5A 4QJCA 4PSTA 5HQZA 4LAHX 3F8YA 2OIPA 4I1NA 2OBCA 4M2XA 3OCHA 3KY8A 3QL3A 4KJKA 3FQFA 1J3JA 4NX7A 4LAGX 1U72A
chains in the Genus database with same CATH topology
3EEMA 4QJZD 1IA4A 1MVSA 4TU5X 4M6JA 3DL6A 5HT4A 3SH2A 1LY3A 2HQPA 1IA3A 4KY4A 1RX6A 3IX9A 3ZPGA 3DAUA 1DG7A 2FZIA 4KEBA 3M09A 3KJRA 3DRCA 1CZ3A 1ZDRA 3FL8A 1DLRA 4IXGX 2C2TA 2AZNA 2ANQA 2W3WA 3FQZA 1DF7A 3EIGA 3I3RA 4M7UA 4G8ZX 2G6VA 3NZ9X 3FYVX 4KM0A 2W3AA 5HVEA 3FRBX 4ELHA 2W9GA 4ELFA 4QI9A 4PSSA 1DRHA 5ECXA 4ELBA 3EEKA 3SA2A 3FQVA 3TQ8A 1RF7A 3JWMA 1PD8A 1SEJA 4H97A 3QLZA 4CD2A 4HOGA 3SRUX 2FZJA 3QGTA 1RC4A 1DHFA 4Q0EA 1PDBA 1RA8A 3KJSA 4KD7A 4QLGA 4DP3A 4OR7A 3SA1A 3F0XX 3NXYA 3UM5A 3EX8A 3E0BA 3F0SX 1DRAA 3F0VX 1AO8A 1RX4A 3SR5X 4DFRA 1IA2A 1OHKA 3F0BX 4P3QA 4KM2A 5JA3A 1RX9A 5CC9A 3IA4A 3TQ9A 3SRQX 4ELGA 2D5NA 3QLYA 4Q0DA 1DISA 4XT6A 1CD2A 2ZZAA 3N0HA 3GHWA 1JOMA 3FQ0A 3UM8A 1PD9A 3F0UX 2W9HA 3K47A 3DGAA 5U27A 3SQYX 1DYRA 2B3ZA 3FY8X 4Q67A 1DHIA 4OSGA 1RA3A 2QK8A 3FRAX 1DREA 4KYAA 3SRSX 3QLWA 4IXFX 1DRBA 3NZAX 3S9UA 3FQCA 3QLSA 3JW3A 1DDSA 3NRRA 4IXED 5U26A 4XT4A 3GHCA 4X5FA 5ECCA 1DR6A 2W9SA 1RG7A 3TQBA 1RH3A 5HPBA 4XE6X 1MVTA 1DR2A 1DYHA 3JSUA 1HFRA 3QLRA 5CCCA 3EEJA 4H96A 1DIUA 1E26A 5HSRA 4FGHA 3KFYA 3NXOA 2GD9A 3I8AX 2LF1A 3INVA 4EIZA 3DATA 3VCOA 1DR7A 2INQA 3S3VA 3UM6A 4KJLA 1M7AA 5FDAA 1VJ3A 3FS6A 3LG4A 1DR4A 3S7AA 1S3WA 4KY8A 4KJJA 1DR5A 4X5GA 3FY9X 1DR1A 2FZHA 3QYLA 3K74A 1DDRA 3Q1HA 4XT5A 3F8ZA 4H95A 3QG2A 1RX1A 2HM9A 3JVXA 4RGCA 3M08A 4ECKA 1KLKA 4Q6AA 3QYOA 5JG0X 1IA1A 3NZ6X 1KMSA 3HJ3A 1JUVA 1DYJA 3GHVA 4M6LA 3NXTA 3RG9A 3JWCA 4G3MA 4HA7A 4P68A 2W9TA 3CLBA 3NTZA 3HBBA 1RA9A 1DG8A 2DHFA 4HA9A 6DFRA 4I13A 8DFRA 2ITHA 1KMVA 4PDJA 3K45A 3KGYA 3FRFX 4H98A 4QHVA 4DPDA 2JYBA 1RA1A 3FYWX 3NU0A 4M6KA 3CL9A 2D0KA 1RX2A 2O7PA 4KBNA 2BLCA 4G95A 1DR3A 3GI2A 1DYIA 3NXXA 2W3BA 4KFJA 4EILA 3EELA 1S3VA 1RD7A 3F91A 2CIGA 3DL5A 1DHJA 2CD2A 2KGKA 1RX5A 2W3MA 4ELEA 1RX3A 1HFPA 2DRCA 4HOEA 3QFXA 1JOLA 4KNEA 2C2SA 3JWFA 2BLAA 1DG5A 2P4GA 3FREX 2HXVA 3SAIA 1RX7A 1BZFA 1YHOA 3FRDX 1S3UA 1M78A 3SRRX 4FHBA 1AI9A 5HI6A 1RE7A 4X5IA 3NZCX 3IA5A 4LAEX 1TDRA 5HUIA 2BL9A 4P3RA 1LUDA 4XT7A 3NZBX 3NZDA 5HF2X 4PTHA 2W3VA 1AOEA 3NXVA 5HQYA 1S3YA 3TQAA 4HOFA 4DPHA 1DRFA 5HT5A 5HSUA 1RB2A 1LY4A 1VDRA 5DXVA 1BOZA 7DFRA 1M79A 2ANOA 3L3RA 3R33A 3FQOA 3ZPCA 1RX8A 4X5HA 1J3IA 2XW7A 3IRNA 3JWKA 4X5JA 3GYFA 1QZFA 1DAJA 3IRMA 5E8QA 4FGGA 5DFRA 1U71A 4QLEA 5HVBA 3QL0A 4PSYA 1J3KA 3QLXA 1DLSA 4KL9A 4KAKA 2L28A 4NX6A 3DG8A 3IROA 3SRWX 4PTJA 4EJ1A 4KLXA 4DDRA 3FL9A 3TD8A 1OHJA 4XECX 3DFRA 1U70A 4M7VA 5EAJA 3RO9A 3CD2A 3JTWA 5HF0X 4QLFA 3D84X 2H2QA 3ROAA 3D80A 4P66A 2BLBA 4XT8A 3NXRA 3OAFA 1RA2A 4EIGA 1RB3A 3K2HA 4LEKX 3CSEA 3SGYA 4XRBA 1D1GA 1HFQA 3F0QX 4GH8A 3JW5A 4QJCA 4PSTA 5HQZA 4LAHX 3F8YA 2OIPA 4I1NA 2OBCA 4M2XA 3OCHA 3KY8A 3QL3A 4KJKA 3FQFA 1J3JA 4NX7A 4LAGX 1U72A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EEM A;  4QJZ D;  1IA4 A;  1MVS A;  4TU5 X;  4M6J A;  3DL6 A;  5HT4 A;  3SH2 A;  1LY3 A;  2HQP A;  1IA3 A;  4KY4 A;  1RX6 A;  3IX9 A;  3ZPG A;  3DAU A;  1DG7 A;  2FZI A;  4KEB A;  3M09 A;  3KJR A;  3DRC A;  1CZ3 A;  1ZDR A;  3FL8 A;  1DLR A;  4IXG X;  2C2T A;  2AZN A;  2ANQ A;  2W3W A;  3FQZ A;  1DF7 A;  3EIG A;  3I3R A;  4M7U A;  4G8Z X;  2G6V A;  3NZ9 X;  3FYV X;  4KM0 A;  2W3A A;  5HVE A;  3FRB X;  4ELH A;  2W9G A;  4ELF A;  4QI9 A;  4PSS A;  1DRH A;  5ECX A;  4ELB A;  3EEK A;  3SA2 A;  3FQV A;  3TQ8 A;  1RF7 A;  3JWM A;  1PD8 A;  1SEJ A;  4H97 A;  3QLZ A;  4CD2 A;  4HOG A;  3SRU X;  2FZJ A;  3QGT A;  1RC4 A;  1DHF A;  4Q0E A;  1PDB A;  1RA8 A;  3KJS A;  4KD7 A;  4QLG A;  4DP3 A;  4OR7 A;  3SA1 A;  3F0X X;  3NXY A;  3UM5 A;  3EX8 A;  3E0B A;  3F0S X;  1DRA A;  3F0V X;  1AO8 A;  1RX4 A;  3SR5 X;  4DFR A;  1IA2 A;  1OHK A;  3F0B X;  4P3Q A;  4KM2 A;  5JA3 A;  1RX9 A;  5CC9 A;  3IA4 A;  3TQ9 A;  3SRQ X;  4ELG A;  2D5N A;  3QLY A;  4Q0D A;  1DIS A;  4XT6 A;  1CD2 A;  2ZZA A;  3N0H A;  3GHW A;  1JOM A;  3FQ0 A;  3UM8 A;  1PD9 A;  3F0U X;  2W9H A;  3K47 A;  3DGA A;  5U27 A;  3SQY X;  1DYR A;  2B3Z A;  3FY8 X;  4Q67 A;  1DHI A;  4OSG A;  1RA3 A;  2QK8 A;  3FRA X;  1DRE A;  4KYA A;  3SRS X;  3QLW A;  4IXF X;  1DRB A;  3NZA X;  3S9U A;  3FQC A;  3QLS A;  3JW3 A;  1DDS A;  3NRR A;  4IXE D;  5U26 A;  4XT4 A;  3GHC A;  4X5F A;  5ECC A;  1DR6 A;  2W9S A;  1RG7 A;  3TQB A;  1RH3 A;  5HPB A;  4XE6 X;  1MVT A;  1DR2 A;  1DYH A;  3JSU A;  1HFR A;  3QLR A;  5CCC A;  3EEJ A;  4H96 A;  1DIU A;  1E26 A;  5HSR A;  4FGH A;  3KFY A;  3NXO A;  2GD9 A;  3I8A X;  2LF1 A;  3INV A;  4EIZ A;  3DAT A;  3VCO A;  1DR7 A;  2INQ A;  3S3V A;  3UM6 A;  4KJL A;  1M7A A;  5FDA A;  1VJ3 A;  3FS6 A;  3LG4 A;  1DR4 A;  3S7A A;  1S3W A;  4KY8 A;  4KJJ A;  1DR5 A;  4X5G A;  3FY9 X;  1DR1 A;  2FZH A;  3QYL A;  3K74 A;  1DDR A;  3Q1H A;  4XT5 A;  3F8Z A;  4H95 A;  3QG2 A;  1RX1 A;  2HM9 A;  3JVX A;  4RGC A;  3M08 A;  4ECK A;  1KLK A;  4Q6A A;  3QYO A;  5JG0 X;  1IA1 A;  3NZ6 X;  1KMS A;  3HJ3 A;  1JUV A;  1DYJ A;  3GHV A;  4M6L A;  3NXT A;  3RG9 A;  3JWC A;  4G3M A;  4HA7 A;  4P68 A;  2W9T A;  3CLB A;  3NTZ A;  3HBB A;  1RA9 A;  1DG8 A;  2DHF A;  4HA9 A;  6DFR A;  4I13 A;  8DFR A;  2ITH A;  1KMV A;  4PDJ A;  3K45 A;  3KGY A;  3FRF X;  4H98 A;  4QHV A;  4DPD A;  2JYB A;  1RA1 A;  3FYW X;  3NU0 A;  4M6K A;  3CL9 A;  2D0K A;  1RX2 A;  2O7P A;  4KBN A;  2BLC A;  4G95 A;  1DR3 A;  3GI2 A;  1DYI A;  3NXX A;  2W3B A;  4KFJ A;  4EIL A;  3EEL A;  1S3V A;  1RD7 A;  3F91 A;  2CIG A;  3DL5 A;  1DHJ A;  2CD2 A;  2KGK A;  1RX5 A;  2W3M A;  4ELE A;  1RX3 A;  1HFP A;  2DRC A;  4HOE A;  3QFX A;  1JOL A;  4KNE A;  2C2S A;  3JWF A;  2BLA A;  1DG5 A;  2P4G A;  3FRE X;  2HXV A;  3SAI A;  1RX7 A;  1BZF A;  1YHO A;  3FRD X;  1S3U A;  1M78 A;  3SRR X;  4FHB A;  1AI9 A;  5HI6 A;  1RE7 A;  4X5I A;  3NZC X;  3IA5 A;  4LAE X;  1TDR A;  5HUI A;  2BL9 A;  4P3R A;  1LUD A;  4XT7 A;  3NZB X;  3NZD A;  5HF2 X;  4PTH A;  2W3V A;  1AOE A;  3NXV A;  5HQY A;  1S3Y A;  3TQA A;  4HOF A;  4DPH A;  1DRF A;  5HT5 A;  5HSU A;  1RB2 A;  1LY4 A;  1VDR A;  5DXV A;  1BOZ A;  7DFR A;  1M79 A;  2ANO A;  3L3R A;  3R33 A;  3FQO A;  3ZPC A;  1RX8 A;  4X5H A;  1J3I A;  2XW7 A;  3IRN A;  3JWK A;  4X5J A;  3GYF A;  1QZF A;  1DAJ A;  3IRM A;  5E8Q A;  4FGG A;  5DFR A;  1U71 A;  4QLE A;  5HVB A;  3QL0 A;  4PSY A;  1J3K A;  3QLX A;  1DLS A;  4KL9 A;  4KAK A;  2L28 A;  4NX6 A;  3DG8 A;  3IRO A;  3SRW X;  4PTJ A;  4EJ1 A;  4KLX A;  4DDR A;  3FL9 A;  3TD8 A;  1OHJ A;  4XEC X;  3DFR A;  1U70 A;  4M7V A;  5EAJ A;  3RO9 A;  3CD2 A;  3JTW A;  5HF0 X;  4QLF A;  3D84 X;  2H2Q A;  3ROA A;  3D80 A;  4P66 A;  2BLB A;  4XT8 A;  3NXR A;  3OAF A;  1RA2 A;  4EIG A;  1RB3 A;  3K2H A;  4LEK X;  3CSE A;  3SGY A;  4XRB A;  1D1G A;  1HFQ A;  3F0Q X;  4GH8 A;  3JW5 A;  4QJC A;  4PST A;  5HQZ A;  4LAH X;  3F8Y A;  2OIP A;  4I1N A;  2OBC A;  4M2X A;  3OCH A;  3KY8 A;  3QL3 A;  4KJK A;  3FQF A;  1J3J A;  4NX7 A;  4LAG X;  1U72 A; 
#chains in the Genus database with same CATH topology
 3EEM A;  4QJZ D;  1IA4 A;  1MVS A;  4TU5 X;  4M6J A;  3DL6 A;  5HT4 A;  3SH2 A;  1LY3 A;  2HQP A;  1IA3 A;  4KY4 A;  1RX6 A;  3IX9 A;  3ZPG A;  3DAU A;  1DG7 A;  2FZI A;  4KEB A;  3M09 A;  3KJR A;  3DRC A;  1CZ3 A;  1ZDR A;  3FL8 A;  1DLR A;  4IXG X;  2C2T A;  2AZN A;  2ANQ A;  2W3W A;  3FQZ A;  1DF7 A;  3EIG A;  3I3R A;  4M7U A;  4G8Z X;  2G6V A;  3NZ9 X;  3FYV X;  4KM0 A;  2W3A A;  5HVE A;  3FRB X;  4ELH A;  2W9G A;  4ELF A;  4QI9 A;  4PSS A;  1DRH A;  5ECX A;  4ELB A;  3EEK A;  3SA2 A;  3FQV A;  3TQ8 A;  1RF7 A;  3JWM A;  1PD8 A;  1SEJ A;  4H97 A;  3QLZ A;  4CD2 A;  4HOG A;  3SRU X;  2FZJ A;  3QGT A;  1RC4 A;  1DHF A;  4Q0E A;  1PDB A;  1RA8 A;  3KJS A;  4KD7 A;  4QLG A;  4DP3 A;  4OR7 A;  3SA1 A;  3F0X X;  3NXY A;  3UM5 A;  3EX8 A;  3E0B A;  3F0S X;  1DRA A;  3F0V X;  1AO8 A;  1RX4 A;  3SR5 X;  4DFR A;  1IA2 A;  1OHK A;  3F0B X;  4P3Q A;  4KM2 A;  5JA3 A;  1RX9 A;  5CC9 A;  3IA4 A;  3TQ9 A;  3SRQ X;  4ELG A;  2D5N A;  3QLY A;  4Q0D A;  1DIS A;  4XT6 A;  1CD2 A;  2ZZA A;  3N0H A;  3GHW A;  1JOM A;  3FQ0 A;  3UM8 A;  1PD9 A;  3F0U X;  2W9H A;  3K47 A;  3DGA A;  5U27 A;  3SQY X;  1DYR A;  2B3Z A;  3FY8 X;  4Q67 A;  1DHI A;  4OSG A;  1RA3 A;  2QK8 A;  3FRA X;  1DRE A;  4KYA A;  3SRS X;  3QLW A;  4IXF X;  1DRB A;  3NZA X;  3S9U A;  3FQC A;  3QLS A;  3JW3 A;  1DDS A;  3NRR A;  4IXE D;  5U26 A;  4XT4 A;  3GHC A;  4X5F A;  5ECC A;  1DR6 A;  2W9S A;  1RG7 A;  3TQB A;  1RH3 A;  5HPB A;  4XE6 X;  1MVT A;  1DR2 A;  1DYH A;  3JSU A;  1HFR A;  3QLR A;  5CCC A;  3EEJ A;  4H96 A;  1DIU A;  1E26 A;  5HSR A;  4FGH A;  3KFY A;  3NXO A;  2GD9 A;  3I8A X;  2LF1 A;  3INV A;  4EIZ A;  3DAT A;  3VCO A;  1DR7 A;  2INQ A;  3S3V A;  3UM6 A;  4KJL A;  1M7A A;  5FDA A;  1VJ3 A;  3FS6 A;  3LG4 A;  1DR4 A;  3S7A A;  1S3W A;  4KY8 A;  4KJJ A;  1DR5 A;  4X5G A;  3FY9 X;  1DR1 A;  2FZH A;  3QYL A;  3K74 A;  1DDR A;  3Q1H A;  4XT5 A;  3F8Z A;  4H95 A;  3QG2 A;  1RX1 A;  2HM9 A;  3JVX A;  4RGC A;  3M08 A;  4ECK A;  1KLK A;  4Q6A A;  3QYO A;  5JG0 X;  1IA1 A;  3NZ6 X;  1KMS A;  3HJ3 A;  1JUV A;  1DYJ A;  3GHV A;  4M6L A;  3NXT A;  3RG9 A;  3JWC A;  4G3M A;  4HA7 A;  4P68 A;  2W9T A;  3CLB A;  3NTZ A;  3HBB A;  1RA9 A;  1DG8 A;  2DHF A;  4HA9 A;  6DFR A;  4I13 A;  8DFR A;  2ITH A;  1KMV A;  4PDJ A;  3K45 A;  3KGY A;  3FRF X;  4H98 A;  4QHV A;  4DPD A;  2JYB A;  1RA1 A;  3FYW X;  3NU0 A;  4M6K A;  3CL9 A;  2D0K A;  1RX2 A;  2O7P A;  4KBN A;  2BLC A;  4G95 A;  1DR3 A;  3GI2 A;  1DYI A;  3NXX A;  2W3B A;  4KFJ A;  4EIL A;  3EEL A;  1S3V A;  1RD7 A;  3F91 A;  2CIG A;  3DL5 A;  1DHJ A;  2CD2 A;  2KGK A;  1RX5 A;  2W3M A;  4ELE A;  1RX3 A;  1HFP A;  2DRC A;  4HOE A;  3QFX A;  1JOL A;  4KNE A;  2C2S A;  3JWF A;  2BLA A;  1DG5 A;  2P4G A;  3FRE X;  2HXV A;  3SAI A;  1RX7 A;  1BZF A;  1YHO A;  3FRD X;  1S3U A;  1M78 A;  3SRR X;  4FHB A;  1AI9 A;  5HI6 A;  1RE7 A;  4X5I A;  3NZC X;  3IA5 A;  4LAE X;  1TDR A;  5HUI A;  2BL9 A;  4P3R A;  1LUD A;  4XT7 A;  3NZB X;  3NZD A;  5HF2 X;  4PTH A;  2W3V A;  1AOE A;  3NXV A;  5HQY A;  1S3Y A;  3TQA A;  4HOF A;  4DPH A;  1DRF A;  5HT5 A;  5HSU A;  1RB2 A;  1LY4 A;  1VDR A;  5DXV A;  1BOZ A;  7DFR A;  1M79 A;  2ANO A;  3L3R A;  3R33 A;  3FQO A;  3ZPC A;  1RX8 A;  4X5H A;  1J3I A;  2XW7 A;  3IRN A;  3JWK A;  4X5J A;  3GYF A;  1QZF A;  1DAJ A;  3IRM A;  5E8Q A;  4FGG A;  5DFR A;  1U71 A;  4QLE A;  5HVB A;  3QL0 A;  4PSY A;  1J3K A;  3QLX A;  1DLS A;  4KL9 A;  4KAK A;  2L28 A;  4NX6 A;  3DG8 A;  3IRO A;  3SRW X;  4PTJ A;  4EJ1 A;  4KLX A;  4DDR A;  3FL9 A;  3TD8 A;  1OHJ A;  4XEC X;  3DFR A;  1U70 A;  4M7V A;  5EAJ A;  3RO9 A;  3CD2 A;  3JTW A;  5HF0 X;  4QLF A;  3D84 X;  2H2Q A;  3ROA A;  3D80 A;  4P66 A;  2BLB A;  4XT8 A;  3NXR A;  3OAF A;  1RA2 A;  4EIG A;  1RB3 A;  3K2H A;  4LEK X;  3CSE A;  3SGY A;  4XRB A;  1D1G A;  1HFQ A;  3F0Q X;  4GH8 A;  3JW5 A;  4QJC A;  4PST A;  5HQZ A;  4LAH X;  3F8Y A;  2OIP A;  4I1N A;  2OBC A;  4M2X A;  3OCH A;  3KY8 A;  3QL3 A;  4KJK A;  3FQF A;  1J3J A;  4NX7 A;  4LAG X;  1U72 A; 
#chains in the Genus database with same CATH homology
 3EEM A;  4QJZ D;  1IA4 A;  1MVS A;  4TU5 X;  4M6J A;  3DL6 A;  5HT4 A;  3SH2 A;  1LY3 A;  2HQP A;  1IA3 A;  4KY4 A;  1RX6 A;  3IX9 A;  3ZPG A;  3DAU A;  1DG7 A;  2FZI A;  4KEB A;  3M09 A;  3KJR A;  3DRC A;  1CZ3 A;  1ZDR A;  3FL8 A;  1DLR A;  4IXG X;  2C2T A;  2AZN A;  2ANQ A;  2W3W A;  3FQZ A;  1DF7 A;  3EIG A;  3I3R A;  4M7U A;  4G8Z X;  2G6V A;  3NZ9 X;  3FYV X;  4KM0 A;  2W3A A;  5HVE A;  3FRB X;  4ELH A;  2W9G A;  4ELF A;  4QI9 A;  4PSS A;  1DRH A;  5ECX A;  4ELB A;  3EEK A;  3SA2 A;  3FQV A;  3TQ8 A;  1RF7 A;  3JWM A;  1PD8 A;  1SEJ A;  4H97 A;  3QLZ A;  4CD2 A;  4HOG A;  3SRU X;  2FZJ A;  3QGT A;  1RC4 A;  1DHF A;  4Q0E A;  1PDB A;  1RA8 A;  3KJS A;  4KD7 A;  4QLG A;  4DP3 A;  4OR7 A;  3SA1 A;  3F0X X;  3NXY A;  3UM5 A;  3EX8 A;  3E0B A;  3F0S X;  1DRA A;  3F0V X;  1AO8 A;  1RX4 A;  3SR5 X;  4DFR A;  1IA2 A;  1OHK A;  3F0B X;  4P3Q A;  4KM2 A;  5JA3 A;  1RX9 A;  5CC9 A;  3IA4 A;  3TQ9 A;  3SRQ X;  4ELG A;  2D5N A;  3QLY A;  4Q0D A;  1DIS A;  4XT6 A;  1CD2 A;  2ZZA A;  3N0H A;  3GHW A;  1JOM A;  3FQ0 A;  3UM8 A;  1PD9 A;  3F0U X;  2W9H A;  3K47 A;  3DGA A;  5U27 A;  3SQY X;  1DYR A;  2B3Z A;  3FY8 X;  4Q67 A;  1DHI A;  4OSG A;  1RA3 A;  2QK8 A;  3FRA X;  1DRE A;  4KYA A;  3SRS X;  3QLW A;  4IXF X;  1DRB A;  3NZA X;  3S9U A;  3FQC A;  3QLS A;  3JW3 A;  1DDS A;  3NRR A;  4IXE D;  5U26 A;  4XT4 A;  3GHC A;  4X5F A;  5ECC A;  1DR6 A;  2W9S A;  1RG7 A;  3TQB A;  1RH3 A;  5HPB A;  4XE6 X;  1MVT A;  1DR2 A;  1DYH A;  3JSU A;  1HFR A;  3QLR A;  5CCC A;  3EEJ A;  4H96 A;  1DIU A;  1E26 A;  5HSR A;  4FGH A;  3KFY A;  3NXO A;  2GD9 A;  3I8A X;  2LF1 A;  3INV A;  4EIZ A;  3DAT A;  3VCO A;  1DR7 A;  2INQ A;  3S3V A;  3UM6 A;  4KJL A;  1M7A A;  5FDA A;  1VJ3 A;  3FS6 A;  3LG4 A;  1DR4 A;  3S7A A;  1S3W A;  4KY8 A;  4KJJ A;  1DR5 A;  4X5G A;  3FY9 X;  1DR1 A;  2FZH A;  3QYL A;  3K74 A;  1DDR A;  3Q1H A;  4XT5 A;  3F8Z A;  4H95 A;  3QG2 A;  1RX1 A;  2HM9 A;  3JVX A;  4RGC A;  3M08 A;  4ECK A;  1KLK A;  4Q6A A;  3QYO A;  5JG0 X;  1IA1 A;  3NZ6 X;  1KMS A;  3HJ3 A;  1JUV A;  1DYJ A;  3GHV A;  4M6L A;  3NXT A;  3RG9 A;  3JWC A;  4G3M A;  4HA7 A;  4P68 A;  2W9T A;  3CLB A;  3NTZ A;  3HBB A;  1RA9 A;  1DG8 A;  2DHF A;  4HA9 A;  6DFR A;  4I13 A;  8DFR A;  2ITH A;  1KMV A;  4PDJ A;  3K45 A;  3KGY A;  3FRF X;  4H98 A;  4QHV A;  4DPD A;  2JYB A;  1RA1 A;  3FYW X;  3NU0 A;  4M6K A;  3CL9 A;  2D0K A;  1RX2 A;  2O7P A;  4KBN A;  2BLC A;  4G95 A;  1DR3 A;  3GI2 A;  1DYI A;  3NXX A;  2W3B A;  4KFJ A;  4EIL A;  3EEL A;  1S3V A;  1RD7 A;  3F91 A;  2CIG A;  3DL5 A;  1DHJ A;  2CD2 A;  2KGK A;  1RX5 A;  2W3M A;  4ELE A;  1RX3 A;  1HFP A;  2DRC A;  4HOE A;  3QFX A;  1JOL A;  4KNE A;  2C2S A;  3JWF A;  2BLA A;  1DG5 A;  2P4G A;  3FRE X;  2HXV A;  3SAI A;  1RX7 A;  1BZF A;  1YHO A;  3FRD X;  1S3U A;  1M78 A;  3SRR X;  4FHB A;  1AI9 A;  5HI6 A;  1RE7 A;  4X5I A;  3NZC X;  3IA5 A;  4LAE X;  1TDR A;  5HUI A;  2BL9 A;  4P3R A;  1LUD A;  4XT7 A;  3NZB X;  3NZD A;  5HF2 X;  4PTH A;  2W3V A;  1AOE A;  3NXV A;  5HQY A;  1S3Y A;  3TQA A;  4HOF A;  4DPH A;  1DRF A;  5HT5 A;  5HSU A;  1RB2 A;  1LY4 A;  1VDR A;  5DXV A;  1BOZ A;  7DFR A;  1M79 A;  2ANO A;  3L3R A;  3R33 A;  3FQO A;  3ZPC A;  1RX8 A;  4X5H A;  1J3I A;  2XW7 A;  3IRN A;  3JWK A;  4X5J A;  3GYF A;  1QZF A;  1DAJ A;  3IRM A;  5E8Q A;  4FGG A;  5DFR A;  1U71 A;  4QLE A;  5HVB A;  3QL0 A;  4PSY A;  1J3K A;  3QLX A;  1DLS A;  4KL9 A;  4KAK A;  2L28 A;  4NX6 A;  3DG8 A;  3IRO A;  3SRW X;  4PTJ A;  4EJ1 A;  4KLX A;  4DDR A;  3FL9 A;  3TD8 A;  1OHJ A;  4XEC X;  3DFR A;  1U70 A;  4M7V A;  5EAJ A;  3RO9 A;  3CD2 A;  3JTW A;  5HF0 X;  4QLF A;  3D84 X;  2H2Q A;  3ROA A;  3D80 A;  4P66 A;  2BLB A;  4XT8 A;  3NXR A;  3OAF A;  1RA2 A;  4EIG A;  1RB3 A;  3K2H A;  4LEK X;  3CSE A;  3SGY A;  4XRB A;  1D1G A;  1HFQ A;  3F0Q X;  4GH8 A;  3JW5 A;  4QJC A;  4PST A;  5HQZ A;  4LAH X;  3F8Y A;  2OIP A;  4I1N A;  2OBC A;  4M2X A;  3OCH A;  3KY8 A;  3QL3 A;  4KJK A;  3FQF A;  1J3J A;  4NX7 A;  4LAG X;  1U72 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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