3SA2A

Bacuills anthracis dihydrofolate reductase bound propargyl-linked tmp analog, ucp1014
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
165
structure length
165
Chain Sequence
HHHMRVSFMVAMDENRVIGKDNNLPWRLPSELQYVKKTTMGHPLIMGRKNYEAIGRPLPGRRNIIVTRNEGYHVEGCEVAHSVEEVFELCKNEEEIFIFGGAQIYDLFLPYVDKLYITKIHHAFEGDTFFPEMDMTNWKEVFVEKGLTDEKNPYTYYYHVYEKQQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title SAR studies of heterocyclic propargyl-linked TMP analogs to Bacillus dihydrofolate reductase
rcsb
molecule keywords Dihydrofolate reductase
molecule tags Oxidoreductase
source organism Bacillus anthracis
total genus 45
structure length 165
sequence length 165
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2011-06-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3sa2A00
4HOFA 4OSGA 1RA9A 5HT4A 3SR5X 3ZPCA 1DG7A 3S9UA 1RA1A 1RE7A 4KJKA 4XT7A 3NZDA 3F0XX 1YHOA 3QGTA 1DR6A 3DRCA 3NXTA 1E26A 2O7PA 7DFRA 1LUDA 3NXRA 1HFQA 5HQZA 4HOEA 1DREA 3E0BA 3IA4A 3QLWA 1KLKA 3QLSA 4ELGA 1DDSA 4KAKA 4M6KA 2W9GA 3QG2A 1AOEA 3GYFA 3QFXA 3S3VA 4X5FA 2XW7A 6DFRA 3JWCA 5HSUA 3DG8A 2ANQA 1DYIA 3SRUX 2DHFA 1CZ3A 3GI2A 1PDBA 2FZJA 3F0UX 4TU5X 4ELEA 5HF2X 3KJRA 1RX1A 1AO8A 2DRCA 3F0VX 3NXVA 1KMSA 4DPHA 1RA3A 2B3ZA 1RA8A 4IXED 4Q6AA 2W3VA 1LY4A 4QHVA 4LAEX 4OR7A 4KNEA 1DRAA 4NX7A 4PSSA 2D5NA 1IA1A 1M78A 4M7UA 3KFYA 3K74A 1OHJA 4XT6A 1OHKA 3RO9A 3SRRX 2JYBA 5EAJA 4ECKA 1IA2A 2ZZAA 1AI9A 3IRMA 4CD2A 4DP3A 3M09A 5JG0X 3QLZA 3QYLA 3FQOA 3CSEA 8DFRA 1BOZA 1TDRA 4FHBA 3FY8X 3QLRA 1DRHA 4QJZD 4FGHA 5HPBA 3FY9X 1DYRA 1DRBA 2OIPA 4GH8A 4X5GA 1DR1A 4PDJA 1LY3A 3DGAA 4ELFA 3IA5A 4KM2A 4X5HA 4M7VA 1J3JA 3TQAA 4PTJA 3EEKA 2HM9A 2L28A 4HOGA 4I13A 1DF7A 3Q1HA 4KJLA 3JWMA 1VJ3A 3HJ3A 5HF0X 2W3MA 1HFRA 2W9SA 3IX9A 3NZCX 2BL9A 4Q0EA 2GD9A 4PSTA 3FRFX 3SRWX 3JVXA 3JSUA 3UM6A 3IRNA 1MVTA 4QLGA 4QLEA 2ITHA 1QZFA 3I3RA 2AZNA 2C2TA 3DL5A 3EIGA 1RC4A 3JW5A 2BLBA 3JWFA 4EIZA 5CC9A 3NZ6X 5HSRA 3FQFA 4G95A 4X5JA 3CL9A 1DYHA 3EEMA 4KD7A 3NRRA 4M2XA 1DG5A 4LAHX 5DXVA 3K47A 1DRFA 4Q67A 1DIUA 1RB3A 3UM8A 3R33A 4XT8A 1DR5A 1DHIA 3DAUA 3SGYA 2QK8A 4HA7A 4KL9A 5DFRA 2KGKA 4XT5A 3QLYA 3ZPGA 3F91A 3IROA 5ECXA 4H98A 1DAJA 5HI6A 3SRQX 1MVSA 4P3RA 4EJ1A 1KMVA 3N0HA 4P66A 3DL6A 2CIGA 1J3KA 3HBBA 1DR3A 3SRSX 3NTZA 1RX7A 5CCCA 3K2HA 3FQCA 3FQVA 1S3WA 1JOMA 1RX5A 1U71A 3QLXA 4XT4A 3TD8A 3DFRA 4ELHA 1DISA 3KY8A 1RX8A 3CLBA 5E8QA 4DFRA 2HXVA 4KFJA 4KLXA 3EEJA 4KEBA 3OAFA 3FL9A 2FZHA 4KM0A 1DR2A 3CD2A 3RG9A 4EIGA 1DLRA 1JOLA 3VCOA 3NU0A 2CD2A 4FGGA 2W3WA 3NZBX 3GHVA 2W3AA 5JA3A 2H2QA 4QJCA 3KGYA 4KY4A 4G8ZX 4QLFA 3OCHA 3ROAA 1JUVA 3FS6A 2C2SA 3NXXA 2BLAA 1DDRA 3TQ8A 4XECX 1HFPA 1U72A 2W3BA 2OBCA 3QL3A 3SA2A 4LAGX 1RX9A 1RA2A 5U26A 2G6VA 1ZDRA 4H95A 3LG4A 2P4GA 3F8YA 4I1NA 4LEKX 1BZFA 4XRBA 3F0QX 1J3IA 4G3MA 3FRBX 2BLCA 4IXFX 3JWKA 3JTWA 5ECCA 1D1GA 1DLSA 1DHFA 4PTHA 3L3RA 3NZ9X 1SEJA 1DHJA 1DG8A 3F8ZA 2D0KA 4M6LA 5HQYA 5HVEA 1DR4A 4ELBA 1RB2A 4HA9A 1S3VA 1RH3A 1M7AA 3FRDX 3GHWA 3K45A 1M79A 3DATA 1S3UA 3UM5A 1RD7A 3SA1A 1VDRA 3M08A 3TQ9A 3NXYA 3GHCA 4DPDA 5HUIA 1DR7A 3I8AX 3SAIA 4RGCA 1PD8A 1S3YA 4H97A 4IXGX 4KBNA 3EELA 2W9HA 2HQPA 5U27A 3FQZA 3QYOA 4QI9A 3FYVX 3S7AA 1DYJA 3FL8A 5FDAA 1CD2A 3KJSA 3EX8A 3NXOA 4H96A 3SH2A 5HT5A 3FQ0A 1IA4A 4KYAA 2ANOA 4DDRA 1PD9A 3NZAX 3FYWX 3F0BX 3QL0A 2W9TA 2INQA 3FREX 1RX3A 4M6JA 3JW3A 4PSYA 3D84X 4EILA 1RG7A 3SQYX 1U70A 4KJJA 3F0SX 4KY8A 4Q0DA 4XE6X 3FRAX 4X5IA 3INVA 5HVBA 1RX6A 4P3QA 1IA3A 3TQBA 1RX4A 1RX2A 3D80A 2LF1A 4P68A 4NX6A 1RF7A 2FZIA
chains in the Genus database with same CATH superfamily
4HOFA 4OSGA 1RA9A 5HT4A 3SR5X 3ZPCA 1DG7A 3S9UA 1RA1A 1RE7A 4KJKA 4XT7A 3NZDA 3F0XX 1YHOA 3QGTA 1DR6A 3DRCA 3NXTA 1E26A 2O7PA 7DFRA 1LUDA 3NXRA 1HFQA 5HQZA 4HOEA 1DREA 3E0BA 3IA4A 3QLWA 1KLKA 3QLSA 4ELGA 1DDSA 4KAKA 4M6KA 2W9GA 3QG2A 1AOEA 3GYFA 3QFXA 3S3VA 4X5FA 2XW7A 6DFRA 3JWCA 5HSUA 3DG8A 2ANQA 1DYIA 3SRUX 2DHFA 1CZ3A 3GI2A 1PDBA 2FZJA 3F0UX 4TU5X 4ELEA 5HF2X 3KJRA 1RX1A 1AO8A 2DRCA 3F0VX 3NXVA 1KMSA 4DPHA 1RA3A 2B3ZA 1RA8A 4IXED 4Q6AA 2W3VA 1LY4A 4QHVA 4LAEX 4OR7A 4KNEA 1DRAA 4NX7A 4PSSA 2D5NA 1IA1A 1M78A 4M7UA 3KFYA 3K74A 1OHJA 4XT6A 1OHKA 3RO9A 3SRRX 2JYBA 5EAJA 4ECKA 1IA2A 2ZZAA 1AI9A 3IRMA 4CD2A 4DP3A 3M09A 5JG0X 3QLZA 3QYLA 3FQOA 3CSEA 8DFRA 1BOZA 1TDRA 4FHBA 3FY8X 3QLRA 1DRHA 4QJZD 4FGHA 5HPBA 3FY9X 1DYRA 1DRBA 2OIPA 4GH8A 4X5GA 1DR1A 4PDJA 1LY3A 3DGAA 4ELFA 3IA5A 4KM2A 4X5HA 4M7VA 1J3JA 3TQAA 4PTJA 3EEKA 2HM9A 2L28A 4HOGA 4I13A 1DF7A 3Q1HA 4KJLA 3JWMA 1VJ3A 3HJ3A 5HF0X 2W3MA 1HFRA 2W9SA 3IX9A 3NZCX 2BL9A 4Q0EA 2GD9A 4PSTA 3FRFX 3SRWX 3JVXA 3JSUA 3UM6A 3IRNA 1MVTA 4QLGA 4QLEA 2ITHA 1QZFA 3I3RA 2AZNA 2C2TA 3DL5A 3EIGA 1RC4A 3JW5A 2BLBA 3JWFA 4EIZA 5CC9A 3NZ6X 5HSRA 3FQFA 4G95A 4X5JA 3CL9A 1DYHA 3EEMA 4KD7A 3NRRA 4M2XA 1DG5A 4LAHX 5DXVA 3K47A 1DRFA 4Q67A 1DIUA 1RB3A 3UM8A 3R33A 4XT8A 1DR5A 1DHIA 3DAUA 3SGYA 2QK8A 4HA7A 4KL9A 5DFRA 2KGKA 4XT5A 3QLYA 3ZPGA 3F91A 3IROA 5ECXA 4H98A 1DAJA 5HI6A 3SRQX 1MVSA 4P3RA 4EJ1A 1KMVA 3N0HA 4P66A 3DL6A 2CIGA 1J3KA 3HBBA 1DR3A 3SRSX 3NTZA 1RX7A 5CCCA 3K2HA 3FQCA 3FQVA 1S3WA 1JOMA 1RX5A 1U71A 3QLXA 4XT4A 3TD8A 3DFRA 4ELHA 1DISA 3KY8A 1RX8A 3CLBA 5E8QA 4DFRA 2HXVA 4KFJA 4KLXA 3EEJA 4KEBA 3OAFA 3FL9A 2FZHA 4KM0A 1DR2A 3CD2A 3RG9A 4EIGA 1DLRA 1JOLA 3VCOA 3NU0A 2CD2A 4FGGA 2W3WA 3NZBX 3GHVA 2W3AA 5JA3A 2H2QA 4QJCA 3KGYA 4KY4A 4G8ZX 4QLFA 3OCHA 3ROAA 1JUVA 3FS6A 2C2SA 3NXXA 2BLAA 1DDRA 3TQ8A 4XECX 1HFPA 1U72A 2W3BA 2OBCA 3QL3A 3SA2A 4LAGX 1RX9A 1RA2A 5U26A 2G6VA 1ZDRA 4H95A 3LG4A 2P4GA 3F8YA 4I1NA 4LEKX 1BZFA 4XRBA 3F0QX 1J3IA 4G3MA 3FRBX 2BLCA 4IXFX 3JWKA 3JTWA 5ECCA 1D1GA 1DLSA 1DHFA 4PTHA 3L3RA 3NZ9X 1SEJA 1DHJA 1DG8A 3F8ZA 2D0KA 4M6LA 5HQYA 5HVEA 1DR4A 4ELBA 1RB2A 4HA9A 1S3VA 1RH3A 1M7AA 3FRDX 3GHWA 3K45A 1M79A 3DATA 1S3UA 3UM5A 1RD7A 3SA1A 1VDRA 3M08A 3TQ9A 3NXYA 3GHCA 4DPDA 5HUIA 1DR7A 3I8AX 3SAIA 4RGCA 1PD8A 1S3YA 4H97A 4IXGX 4KBNA 3EELA 2W9HA 2HQPA 5U27A 3FQZA 3QYOA 4QI9A 3FYVX 3S7AA 1DYJA 3FL8A 5FDAA 1CD2A 3KJSA 3EX8A 3NXOA 4H96A 3SH2A 5HT5A 3FQ0A 1IA4A 4KYAA 2ANOA 4DDRA 1PD9A 3NZAX 3FYWX 3F0BX 3QL0A 2W9TA 2INQA 3FREX 1RX3A 4M6JA 3JW3A 4PSYA 3D84X 4EILA 1RG7A 3SQYX 1U70A 4KJJA 3F0SX 4KY8A 4Q0DA 4XE6X 3FRAX 4X5IA 3INVA 5HVBA 1RX6A 4P3QA 1IA3A 3TQBA 1RX4A 1RX2A 3D80A 2LF1A 4P68A 4NX6A 1RF7A 2FZIA
chains in the Genus database with same CATH topology
4HOFA 4OSGA 1RA9A 5HT4A 3SR5X 3ZPCA 1DG7A 3S9UA 1RA1A 1RE7A 4KJKA 4XT7A 3NZDA 3F0XX 1YHOA 3QGTA 1DR6A 3DRCA 3NXTA 1E26A 2O7PA 7DFRA 1LUDA 3NXRA 1HFQA 5HQZA 4HOEA 1DREA 3E0BA 3IA4A 3QLWA 1KLKA 3QLSA 4ELGA 1DDSA 4KAKA 4M6KA 2W9GA 3QG2A 1AOEA 3GYFA 3QFXA 3S3VA 4X5FA 2XW7A 6DFRA 3JWCA 5HSUA 3DG8A 2ANQA 1DYIA 3SRUX 2DHFA 1CZ3A 3GI2A 1PDBA 2FZJA 3F0UX 4TU5X 4ELEA 5HF2X 3KJRA 1RX1A 1AO8A 2DRCA 3F0VX 3NXVA 1KMSA 4DPHA 1RA3A 2B3ZA 1RA8A 4IXED 4Q6AA 2W3VA 1LY4A 4QHVA 4LAEX 4OR7A 4KNEA 1DRAA 4NX7A 4PSSA 2D5NA 1IA1A 1M78A 4M7UA 3KFYA 3K74A 1OHJA 4XT6A 1OHKA 3RO9A 3SRRX 2JYBA 5EAJA 4ECKA 1IA2A 2ZZAA 1AI9A 3IRMA 4CD2A 4DP3A 3M09A 5JG0X 3QLZA 3QYLA 3FQOA 3CSEA 8DFRA 1BOZA 1TDRA 4FHBA 3FY8X 3QLRA 1DRHA 4QJZD 4FGHA 5HPBA 3FY9X 1DYRA 1DRBA 2OIPA 4GH8A 4X5GA 1DR1A 4PDJA 1LY3A 3DGAA 4ELFA 3IA5A 4KM2A 4X5HA 4M7VA 1J3JA 3TQAA 4PTJA 3EEKA 2HM9A 2L28A 4HOGA 4I13A 1DF7A 3Q1HA 4KJLA 3JWMA 1VJ3A 3HJ3A 5HF0X 2W3MA 1HFRA 2W9SA 3IX9A 3NZCX 2BL9A 4Q0EA 2GD9A 4PSTA 3FRFX 3SRWX 3JVXA 3JSUA 3UM6A 3IRNA 1MVTA 4QLGA 4QLEA 2ITHA 1QZFA 3I3RA 2AZNA 2C2TA 3DL5A 3EIGA 1RC4A 3JW5A 2BLBA 3JWFA 4EIZA 5CC9A 3NZ6X 5HSRA 3FQFA 4G95A 4X5JA 3CL9A 1DYHA 3EEMA 4KD7A 3NRRA 4M2XA 1DG5A 4LAHX 5DXVA 3K47A 1DRFA 4Q67A 1DIUA 1RB3A 3UM8A 3R33A 4XT8A 1DR5A 1DHIA 3DAUA 3SGYA 2QK8A 4HA7A 4KL9A 5DFRA 2KGKA 4XT5A 3QLYA 3ZPGA 3F91A 3IROA 5ECXA 4H98A 1DAJA 5HI6A 3SRQX 1MVSA 4P3RA 4EJ1A 1KMVA 3N0HA 4P66A 3DL6A 2CIGA 1J3KA 3HBBA 1DR3A 3SRSX 3NTZA 1RX7A 5CCCA 3K2HA 3FQCA 3FQVA 1S3WA 1JOMA 1RX5A 1U71A 3QLXA 4XT4A 3TD8A 3DFRA 4ELHA 1DISA 3KY8A 1RX8A 3CLBA 5E8QA 4DFRA 2HXVA 4KFJA 4KLXA 3EEJA 4KEBA 3OAFA 3FL9A 2FZHA 4KM0A 1DR2A 3CD2A 3RG9A 4EIGA 1DLRA 1JOLA 3VCOA 3NU0A 2CD2A 4FGGA 2W3WA 3NZBX 3GHVA 2W3AA 5JA3A 2H2QA 4QJCA 3KGYA 4KY4A 4G8ZX 4QLFA 3OCHA 3ROAA 1JUVA 3FS6A 2C2SA 3NXXA 2BLAA 1DDRA 3TQ8A 4XECX 1HFPA 1U72A 2W3BA 2OBCA 3QL3A 3SA2A 4LAGX 1RX9A 1RA2A 5U26A 2G6VA 1ZDRA 4H95A 3LG4A 2P4GA 3F8YA 4I1NA 4LEKX 1BZFA 4XRBA 3F0QX 1J3IA 4G3MA 3FRBX 2BLCA 4IXFX 3JWKA 3JTWA 5ECCA 1D1GA 1DLSA 1DHFA 4PTHA 3L3RA 3NZ9X 1SEJA 1DHJA 1DG8A 3F8ZA 2D0KA 4M6LA 5HQYA 5HVEA 1DR4A 4ELBA 1RB2A 4HA9A 1S3VA 1RH3A 1M7AA 3FRDX 3GHWA 3K45A 1M79A 3DATA 1S3UA 3UM5A 1RD7A 3SA1A 1VDRA 3M08A 3TQ9A 3NXYA 3GHCA 4DPDA 5HUIA 1DR7A 3I8AX 3SAIA 4RGCA 1PD8A 1S3YA 4H97A 4IXGX 4KBNA 3EELA 2W9HA 2HQPA 5U27A 3FQZA 3QYOA 4QI9A 3FYVX 3S7AA 1DYJA 3FL8A 5FDAA 1CD2A 3KJSA 3EX8A 3NXOA 4H96A 3SH2A 5HT5A 3FQ0A 1IA4A 4KYAA 2ANOA 4DDRA 1PD9A 3NZAX 3FYWX 3F0BX 3QL0A 2W9TA 2INQA 3FREX 1RX3A 4M6JA 3JW3A 4PSYA 3D84X 4EILA 1RG7A 3SQYX 1U70A 4KJJA 3F0SX 4KY8A 4Q0DA 4XE6X 3FRAX 4X5IA 3INVA 5HVBA 1RX6A 4P3QA 1IA3A 3TQBA 1RX4A 1RX2A 3D80A 2LF1A 4P68A 4NX6A 1RF7A 2FZIA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4HOF A;  4OSG A;  1RA9 A;  5HT4 A;  3SR5 X;  3ZPC A;  1DG7 A;  3S9U A;  1RA1 A;  1RE7 A;  4KJK A;  4XT7 A;  3NZD A;  3F0X X;  1YHO A;  3QGT A;  1DR6 A;  3DRC A;  3NXT A;  1E26 A;  2O7P A;  7DFR A;  1LUD A;  3NXR A;  1HFQ A;  5HQZ A;  4HOE A;  1DRE A;  3E0B A;  3IA4 A;  3QLW A;  1KLK A;  3QLS A;  4ELG A;  1DDS A;  4KAK A;  4M6K A;  2W9G A;  3QG2 A;  1AOE A;  3GYF A;  3QFX A;  3S3V A;  4X5F A;  2XW7 A;  6DFR A;  3JWC A;  5HSU A;  3DG8 A;  2ANQ A;  1DYI A;  3SRU X;  2DHF A;  1CZ3 A;  3GI2 A;  1PDB A;  2FZJ A;  3F0U X;  4TU5 X;  4ELE A;  5HF2 X;  3KJR A;  1RX1 A;  1AO8 A;  2DRC A;  3F0V X;  3NXV A;  1KMS A;  4DPH A;  1RA3 A;  2B3Z A;  1RA8 A;  4IXE D;  4Q6A A;  2W3V A;  1LY4 A;  4QHV A;  4LAE X;  4OR7 A;  4KNE A;  1DRA A;  4NX7 A;  4PSS A;  2D5N A;  1IA1 A;  1M78 A;  4M7U A;  3KFY A;  3K74 A;  1OHJ A;  4XT6 A;  1OHK A;  3RO9 A;  3SRR X;  2JYB A;  5EAJ A;  4ECK A;  1IA2 A;  2ZZA A;  1AI9 A;  3IRM A;  4CD2 A;  4DP3 A;  3M09 A;  5JG0 X;  3QLZ A;  3QYL A;  3FQO A;  3CSE A;  8DFR A;  1BOZ A;  1TDR A;  4FHB A;  3FY8 X;  3QLR A;  1DRH A;  4QJZ D;  4FGH A;  5HPB A;  3FY9 X;  1DYR A;  1DRB A;  2OIP A;  4GH8 A;  4X5G A;  1DR1 A;  4PDJ A;  1LY3 A;  3DGA A;  4ELF A;  3IA5 A;  4KM2 A;  4X5H A;  4M7V A;  1J3J A;  3TQA A;  4PTJ A;  3EEK A;  2HM9 A;  2L28 A;  4HOG A;  4I13 A;  1DF7 A;  3Q1H A;  4KJL A;  3JWM A;  1VJ3 A;  3HJ3 A;  5HF0 X;  2W3M A;  1HFR A;  2W9S A;  3IX9 A;  3NZC X;  2BL9 A;  4Q0E A;  2GD9 A;  4PST A;  3FRF X;  3SRW X;  3JVX A;  3JSU A;  3UM6 A;  3IRN A;  1MVT A;  4QLG A;  4QLE A;  2ITH A;  1QZF A;  3I3R A;  2AZN A;  2C2T A;  3DL5 A;  3EIG A;  1RC4 A;  3JW5 A;  2BLB A;  3JWF A;  4EIZ A;  5CC9 A;  3NZ6 X;  5HSR A;  3FQF A;  4G95 A;  4X5J A;  3CL9 A;  1DYH A;  3EEM A;  4KD7 A;  3NRR A;  4M2X A;  1DG5 A;  4LAH X;  5DXV A;  3K47 A;  1DRF A;  4Q67 A;  1DIU A;  1RB3 A;  3UM8 A;  3R33 A;  4XT8 A;  1DR5 A;  1DHI A;  3DAU A;  3SGY A;  2QK8 A;  4HA7 A;  4KL9 A;  5DFR A;  2KGK A;  4XT5 A;  3QLY A;  3ZPG A;  3F91 A;  3IRO A;  5ECX A;  4H98 A;  1DAJ A;  5HI6 A;  3SRQ X;  1MVS A;  4P3R A;  4EJ1 A;  1KMV A;  3N0H A;  4P66 A;  3DL6 A;  2CIG A;  1J3K A;  3HBB A;  1DR3 A;  3SRS X;  3NTZ A;  1RX7 A;  5CCC A;  3K2H A;  3FQC A;  3FQV A;  1S3W A;  1JOM A;  1RX5 A;  1U71 A;  3QLX A;  4XT4 A;  3TD8 A;  3DFR A;  4ELH A;  1DIS A;  3KY8 A;  1RX8 A;  3CLB A;  5E8Q A;  4DFR A;  2HXV A;  4KFJ A;  4KLX A;  3EEJ A;  4KEB A;  3OAF A;  3FL9 A;  2FZH A;  4KM0 A;  1DR2 A;  3CD2 A;  3RG9 A;  4EIG A;  1DLR A;  1JOL A;  3VCO A;  3NU0 A;  2CD2 A;  4FGG A;  2W3W A;  3NZB X;  3GHV A;  2W3A A;  5JA3 A;  2H2Q A;  4QJC A;  3KGY A;  4KY4 A;  4G8Z X;  4QLF A;  3OCH A;  3ROA A;  1JUV A;  3FS6 A;  2C2S A;  3NXX A;  2BLA A;  1DDR A;  3TQ8 A;  4XEC X;  1HFP A;  1U72 A;  2W3B A;  2OBC A;  3QL3 A;  3SA2 A;  4LAG X;  1RX9 A;  1RA2 A;  5U26 A;  2G6V A;  1ZDR A;  4H95 A;  3LG4 A;  2P4G A;  3F8Y A;  4I1N A;  4LEK X;  1BZF A;  4XRB A;  3F0Q X;  1J3I A;  4G3M A;  3FRB X;  2BLC A;  4IXF X;  3JWK A;  3JTW A;  5ECC A;  1D1G A;  1DLS A;  1DHF A;  4PTH A;  3L3R A;  3NZ9 X;  1SEJ A;  1DHJ A;  1DG8 A;  3F8Z A;  2D0K A;  4M6L A;  5HQY A;  5HVE A;  1DR4 A;  4ELB A;  1RB2 A;  4HA9 A;  1S3V A;  1RH3 A;  1M7A A;  3FRD X;  3GHW A;  3K45 A;  1M79 A;  3DAT A;  1S3U A;  3UM5 A;  1RD7 A;  3SA1 A;  1VDR A;  3M08 A;  3TQ9 A;  3NXY A;  3GHC A;  4DPD A;  5HUI A;  1DR7 A;  3I8A X;  3SAI A;  4RGC A;  1PD8 A;  1S3Y A;  4H97 A;  4IXG X;  4KBN A;  3EEL A;  2W9H A;  2HQP A;  5U27 A;  3FQZ A;  3QYO A;  4QI9 A;  3FYV X;  3S7A A;  1DYJ A;  3FL8 A;  5FDA A;  1CD2 A;  3KJS A;  3EX8 A;  3NXO A;  4H96 A;  3SH2 A;  5HT5 A;  3FQ0 A;  1IA4 A;  4KYA A;  2ANO A;  4DDR A;  1PD9 A;  3NZA X;  3FYW X;  3F0B X;  3QL0 A;  2W9T A;  2INQ A;  3FRE X;  1RX3 A;  4M6J A;  3JW3 A;  4PSY A;  3D84 X;  4EIL A;  1RG7 A;  3SQY X;  1U70 A;  4KJJ A;  3F0S X;  4KY8 A;  4Q0D A;  4XE6 X;  3FRA X;  4X5I A;  3INV A;  5HVB A;  1RX6 A;  4P3Q A;  1IA3 A;  3TQB A;  1RX4 A;  1RX2 A;  3D80 A;  2LF1 A;  4P68 A;  4NX6 A;  1RF7 A;  2FZI A; 
#chains in the Genus database with same CATH topology
 4HOF A;  4OSG A;  1RA9 A;  5HT4 A;  3SR5 X;  3ZPC A;  1DG7 A;  3S9U A;  1RA1 A;  1RE7 A;  4KJK A;  4XT7 A;  3NZD A;  3F0X X;  1YHO A;  3QGT A;  1DR6 A;  3DRC A;  3NXT A;  1E26 A;  2O7P A;  7DFR A;  1LUD A;  3NXR A;  1HFQ A;  5HQZ A;  4HOE A;  1DRE A;  3E0B A;  3IA4 A;  3QLW A;  1KLK A;  3QLS A;  4ELG A;  1DDS A;  4KAK A;  4M6K A;  2W9G A;  3QG2 A;  1AOE A;  3GYF A;  3QFX A;  3S3V A;  4X5F A;  2XW7 A;  6DFR A;  3JWC A;  5HSU A;  3DG8 A;  2ANQ A;  1DYI A;  3SRU X;  2DHF A;  1CZ3 A;  3GI2 A;  1PDB A;  2FZJ A;  3F0U X;  4TU5 X;  4ELE A;  5HF2 X;  3KJR A;  1RX1 A;  1AO8 A;  2DRC A;  3F0V X;  3NXV A;  1KMS A;  4DPH A;  1RA3 A;  2B3Z A;  1RA8 A;  4IXE D;  4Q6A A;  2W3V A;  1LY4 A;  4QHV A;  4LAE X;  4OR7 A;  4KNE A;  1DRA A;  4NX7 A;  4PSS A;  2D5N A;  1IA1 A;  1M78 A;  4M7U A;  3KFY A;  3K74 A;  1OHJ A;  4XT6 A;  1OHK A;  3RO9 A;  3SRR X;  2JYB A;  5EAJ A;  4ECK A;  1IA2 A;  2ZZA A;  1AI9 A;  3IRM A;  4CD2 A;  4DP3 A;  3M09 A;  5JG0 X;  3QLZ A;  3QYL A;  3FQO A;  3CSE A;  8DFR A;  1BOZ A;  1TDR A;  4FHB A;  3FY8 X;  3QLR A;  1DRH A;  4QJZ D;  4FGH A;  5HPB A;  3FY9 X;  1DYR A;  1DRB A;  2OIP A;  4GH8 A;  4X5G A;  1DR1 A;  4PDJ A;  1LY3 A;  3DGA A;  4ELF A;  3IA5 A;  4KM2 A;  4X5H A;  4M7V A;  1J3J A;  3TQA A;  4PTJ A;  3EEK A;  2HM9 A;  2L28 A;  4HOG A;  4I13 A;  1DF7 A;  3Q1H A;  4KJL A;  3JWM A;  1VJ3 A;  3HJ3 A;  5HF0 X;  2W3M A;  1HFR A;  2W9S A;  3IX9 A;  3NZC X;  2BL9 A;  4Q0E A;  2GD9 A;  4PST A;  3FRF X;  3SRW X;  3JVX A;  3JSU A;  3UM6 A;  3IRN A;  1MVT A;  4QLG A;  4QLE A;  2ITH A;  1QZF A;  3I3R A;  2AZN A;  2C2T A;  3DL5 A;  3EIG A;  1RC4 A;  3JW5 A;  2BLB A;  3JWF A;  4EIZ A;  5CC9 A;  3NZ6 X;  5HSR A;  3FQF A;  4G95 A;  4X5J A;  3CL9 A;  1DYH A;  3EEM A;  4KD7 A;  3NRR A;  4M2X A;  1DG5 A;  4LAH X;  5DXV A;  3K47 A;  1DRF A;  4Q67 A;  1DIU A;  1RB3 A;  3UM8 A;  3R33 A;  4XT8 A;  1DR5 A;  1DHI A;  3DAU A;  3SGY A;  2QK8 A;  4HA7 A;  4KL9 A;  5DFR A;  2KGK A;  4XT5 A;  3QLY A;  3ZPG A;  3F91 A;  3IRO A;  5ECX A;  4H98 A;  1DAJ A;  5HI6 A;  3SRQ X;  1MVS A;  4P3R A;  4EJ1 A;  1KMV A;  3N0H A;  4P66 A;  3DL6 A;  2CIG A;  1J3K A;  3HBB A;  1DR3 A;  3SRS X;  3NTZ A;  1RX7 A;  5CCC A;  3K2H A;  3FQC A;  3FQV A;  1S3W A;  1JOM A;  1RX5 A;  1U71 A;  3QLX A;  4XT4 A;  3TD8 A;  3DFR A;  4ELH A;  1DIS A;  3KY8 A;  1RX8 A;  3CLB A;  5E8Q A;  4DFR A;  2HXV A;  4KFJ A;  4KLX A;  3EEJ A;  4KEB A;  3OAF A;  3FL9 A;  2FZH A;  4KM0 A;  1DR2 A;  3CD2 A;  3RG9 A;  4EIG A;  1DLR A;  1JOL A;  3VCO A;  3NU0 A;  2CD2 A;  4FGG A;  2W3W A;  3NZB X;  3GHV A;  2W3A A;  5JA3 A;  2H2Q A;  4QJC A;  3KGY A;  4KY4 A;  4G8Z X;  4QLF A;  3OCH A;  3ROA A;  1JUV A;  3FS6 A;  2C2S A;  3NXX A;  2BLA A;  1DDR A;  3TQ8 A;  4XEC X;  1HFP A;  1U72 A;  2W3B A;  2OBC A;  3QL3 A;  3SA2 A;  4LAG X;  1RX9 A;  1RA2 A;  5U26 A;  2G6V A;  1ZDR A;  4H95 A;  3LG4 A;  2P4G A;  3F8Y A;  4I1N A;  4LEK X;  1BZF A;  4XRB A;  3F0Q X;  1J3I A;  4G3M A;  3FRB X;  2BLC A;  4IXF X;  3JWK A;  3JTW A;  5ECC A;  1D1G A;  1DLS A;  1DHF A;  4PTH A;  3L3R A;  3NZ9 X;  1SEJ A;  1DHJ A;  1DG8 A;  3F8Z A;  2D0K A;  4M6L A;  5HQY A;  5HVE A;  1DR4 A;  4ELB A;  1RB2 A;  4HA9 A;  1S3V A;  1RH3 A;  1M7A A;  3FRD X;  3GHW A;  3K45 A;  1M79 A;  3DAT A;  1S3U A;  3UM5 A;  1RD7 A;  3SA1 A;  1VDR A;  3M08 A;  3TQ9 A;  3NXY A;  3GHC A;  4DPD A;  5HUI A;  1DR7 A;  3I8A X;  3SAI A;  4RGC A;  1PD8 A;  1S3Y A;  4H97 A;  4IXG X;  4KBN A;  3EEL A;  2W9H A;  2HQP A;  5U27 A;  3FQZ A;  3QYO A;  4QI9 A;  3FYV X;  3S7A A;  1DYJ A;  3FL8 A;  5FDA A;  1CD2 A;  3KJS A;  3EX8 A;  3NXO A;  4H96 A;  3SH2 A;  5HT5 A;  3FQ0 A;  1IA4 A;  4KYA A;  2ANO A;  4DDR A;  1PD9 A;  3NZA X;  3FYW X;  3F0B X;  3QL0 A;  2W9T A;  2INQ A;  3FRE X;  1RX3 A;  4M6J A;  3JW3 A;  4PSY A;  3D84 X;  4EIL A;  1RG7 A;  3SQY X;  1U70 A;  4KJJ A;  3F0S X;  4KY8 A;  4Q0D A;  4XE6 X;  3FRA X;  4X5I A;  3INV A;  5HVB A;  1RX6 A;  4P3Q A;  1IA3 A;  3TQB A;  1RX4 A;  1RX2 A;  3D80 A;  2LF1 A;  4P68 A;  4NX6 A;  1RF7 A;  2FZI A; 
#chains in the Genus database with same CATH homology
 4HOF A;  4OSG A;  1RA9 A;  5HT4 A;  3SR5 X;  3ZPC A;  1DG7 A;  3S9U A;  1RA1 A;  1RE7 A;  4KJK A;  4XT7 A;  3NZD A;  3F0X X;  1YHO A;  3QGT A;  1DR6 A;  3DRC A;  3NXT A;  1E26 A;  2O7P A;  7DFR A;  1LUD A;  3NXR A;  1HFQ A;  5HQZ A;  4HOE A;  1DRE A;  3E0B A;  3IA4 A;  3QLW A;  1KLK A;  3QLS A;  4ELG A;  1DDS A;  4KAK A;  4M6K A;  2W9G A;  3QG2 A;  1AOE A;  3GYF A;  3QFX A;  3S3V A;  4X5F A;  2XW7 A;  6DFR A;  3JWC A;  5HSU A;  3DG8 A;  2ANQ A;  1DYI A;  3SRU X;  2DHF A;  1CZ3 A;  3GI2 A;  1PDB A;  2FZJ A;  3F0U X;  4TU5 X;  4ELE A;  5HF2 X;  3KJR A;  1RX1 A;  1AO8 A;  2DRC A;  3F0V X;  3NXV A;  1KMS A;  4DPH A;  1RA3 A;  2B3Z A;  1RA8 A;  4IXE D;  4Q6A A;  2W3V A;  1LY4 A;  4QHV A;  4LAE X;  4OR7 A;  4KNE A;  1DRA A;  4NX7 A;  4PSS A;  2D5N A;  1IA1 A;  1M78 A;  4M7U A;  3KFY A;  3K74 A;  1OHJ A;  4XT6 A;  1OHK A;  3RO9 A;  3SRR X;  2JYB A;  5EAJ A;  4ECK A;  1IA2 A;  2ZZA A;  1AI9 A;  3IRM A;  4CD2 A;  4DP3 A;  3M09 A;  5JG0 X;  3QLZ A;  3QYL A;  3FQO A;  3CSE A;  8DFR A;  1BOZ A;  1TDR A;  4FHB A;  3FY8 X;  3QLR A;  1DRH A;  4QJZ D;  4FGH A;  5HPB A;  3FY9 X;  1DYR A;  1DRB A;  2OIP A;  4GH8 A;  4X5G A;  1DR1 A;  4PDJ A;  1LY3 A;  3DGA A;  4ELF A;  3IA5 A;  4KM2 A;  4X5H A;  4M7V A;  1J3J A;  3TQA A;  4PTJ A;  3EEK A;  2HM9 A;  2L28 A;  4HOG A;  4I13 A;  1DF7 A;  3Q1H A;  4KJL A;  3JWM A;  1VJ3 A;  3HJ3 A;  5HF0 X;  2W3M A;  1HFR A;  2W9S A;  3IX9 A;  3NZC X;  2BL9 A;  4Q0E A;  2GD9 A;  4PST A;  3FRF X;  3SRW X;  3JVX A;  3JSU A;  3UM6 A;  3IRN A;  1MVT A;  4QLG A;  4QLE A;  2ITH A;  1QZF A;  3I3R A;  2AZN A;  2C2T A;  3DL5 A;  3EIG A;  1RC4 A;  3JW5 A;  2BLB A;  3JWF A;  4EIZ A;  5CC9 A;  3NZ6 X;  5HSR A;  3FQF A;  4G95 A;  4X5J A;  3CL9 A;  1DYH A;  3EEM A;  4KD7 A;  3NRR A;  4M2X A;  1DG5 A;  4LAH X;  5DXV A;  3K47 A;  1DRF A;  4Q67 A;  1DIU A;  1RB3 A;  3UM8 A;  3R33 A;  4XT8 A;  1DR5 A;  1DHI A;  3DAU A;  3SGY A;  2QK8 A;  4HA7 A;  4KL9 A;  5DFR A;  2KGK A;  4XT5 A;  3QLY A;  3ZPG A;  3F91 A;  3IRO A;  5ECX A;  4H98 A;  1DAJ A;  5HI6 A;  3SRQ X;  1MVS A;  4P3R A;  4EJ1 A;  1KMV A;  3N0H A;  4P66 A;  3DL6 A;  2CIG A;  1J3K A;  3HBB A;  1DR3 A;  3SRS X;  3NTZ A;  1RX7 A;  5CCC A;  3K2H A;  3FQC A;  3FQV A;  1S3W A;  1JOM A;  1RX5 A;  1U71 A;  3QLX A;  4XT4 A;  3TD8 A;  3DFR A;  4ELH A;  1DIS A;  3KY8 A;  1RX8 A;  3CLB A;  5E8Q A;  4DFR A;  2HXV A;  4KFJ A;  4KLX A;  3EEJ A;  4KEB A;  3OAF A;  3FL9 A;  2FZH A;  4KM0 A;  1DR2 A;  3CD2 A;  3RG9 A;  4EIG A;  1DLR A;  1JOL A;  3VCO A;  3NU0 A;  2CD2 A;  4FGG A;  2W3W A;  3NZB X;  3GHV A;  2W3A A;  5JA3 A;  2H2Q A;  4QJC A;  3KGY A;  4KY4 A;  4G8Z X;  4QLF A;  3OCH A;  3ROA A;  1JUV A;  3FS6 A;  2C2S A;  3NXX A;  2BLA A;  1DDR A;  3TQ8 A;  4XEC X;  1HFP A;  1U72 A;  2W3B A;  2OBC A;  3QL3 A;  3SA2 A;  4LAG X;  1RX9 A;  1RA2 A;  5U26 A;  2G6V A;  1ZDR A;  4H95 A;  3LG4 A;  2P4G A;  3F8Y A;  4I1N A;  4LEK X;  1BZF A;  4XRB A;  3F0Q X;  1J3I A;  4G3M A;  3FRB X;  2BLC A;  4IXF X;  3JWK A;  3JTW A;  5ECC A;  1D1G A;  1DLS A;  1DHF A;  4PTH A;  3L3R A;  3NZ9 X;  1SEJ A;  1DHJ A;  1DG8 A;  3F8Z A;  2D0K A;  4M6L A;  5HQY A;  5HVE A;  1DR4 A;  4ELB A;  1RB2 A;  4HA9 A;  1S3V A;  1RH3 A;  1M7A A;  3FRD X;  3GHW A;  3K45 A;  1M79 A;  3DAT A;  1S3U A;  3UM5 A;  1RD7 A;  3SA1 A;  1VDR A;  3M08 A;  3TQ9 A;  3NXY A;  3GHC A;  4DPD A;  5HUI A;  1DR7 A;  3I8A X;  3SAI A;  4RGC A;  1PD8 A;  1S3Y A;  4H97 A;  4IXG X;  4KBN A;  3EEL A;  2W9H A;  2HQP A;  5U27 A;  3FQZ A;  3QYO A;  4QI9 A;  3FYV X;  3S7A A;  1DYJ A;  3FL8 A;  5FDA A;  1CD2 A;  3KJS A;  3EX8 A;  3NXO A;  4H96 A;  3SH2 A;  5HT5 A;  3FQ0 A;  1IA4 A;  4KYA A;  2ANO A;  4DDR A;  1PD9 A;  3NZA X;  3FYW X;  3F0B X;  3QL0 A;  2W9T A;  2INQ A;  3FRE X;  1RX3 A;  4M6J A;  3JW3 A;  4PSY A;  3D84 X;  4EIL A;  1RG7 A;  3SQY X;  1U70 A;  4KJJ A;  3F0S X;  4KY8 A;  4Q0D A;  4XE6 X;  3FRA X;  4X5I A;  3INV A;  5HVB A;  1RX6 A;  4P3Q A;  1IA3 A;  3TQB A;  1RX4 A;  1RX2 A;  3D80 A;  2LF1 A;  4P68 A;  4NX6 A;  1RF7 A;  2FZI A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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