3SH2A

Staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-(3-(4-methoxybiphenyl-3-yl)prop-1-ynyl)pyrimidine-2,4-diamine (ucp120j)
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes.
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Staphylococcus aureus
molecule keywords Dihydrofolate reductase
total genus 41
structure length 157
sequence length 157
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2011-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3sh2A00
3SRRX 3QL3A 3QLYA 4KFJA 4HA7A 5HI6A 4DPHA 2W3BA 2HXVA 2B3ZA 4DP3A 4LEKX 1RA8A 1RG7A 1RH3A 1RX3A 3NXYA 4M6KA 3FRDX 3JWFA 1RX8A 2JYBA 3KJRA 4EILA 2FZJA 3L3RA 4XT5A 3ZPGA 3EELA 5HUIA 2W3VA 2ZZAA 1DRAA 5HSRA 4KY4A 5JG0X 4KJJA 1KMVA 2QK8A 4QHVA 4QJCA 4KAKA 1DR7A 3Q1HA 2LF1A 1DDRA 3ROAA 1DR6A 1U72A 5U26A 3NZ9X 4KM0A 3IRNA 4G3MA 3JW5A 1DR5A 3KGYA 4EJ1A 4PSTA 4G8ZX 3OAFA 3SRUX 3E0BA 3DL5A 1DIUA 4KEBA 3SA1A 3DGAA 1HFRA 3LG4A 2BLCA 4X5IA 1OHJA 1U71A 4XRBA 1RA3A 3GI2A 4M7VA 3IA5A 1U70A 4X5HA 8DFRA 3N0HA 3EEMA 2ITHA 1RX5A 2W9GA 3JWMA 4ECKA 3R33A 2BLAA 5HF0X 3K74A 3I8AX 4DDRA 4DFRA 2W9SA 1AO8A 4HA9A 1DLSA 2FZIA 3SH2A 5DXVA 1VJ3A 2W9HA 7DFRA 3FYWX 1M78A 1DHFA 3FQCA 1J3KA 5HF2X 1ZDRA 4DPDA 3FY8X 1RX4A 4I13A 4M7UA 4Q0EA 3TQ9A 3F0QX 2CD2A 3SGYA 3JVXA 2ANQA 1DYJA 5HPBA 4EIZA 1AI9A 6DFRA 1S3VA 1DR2A 1DHIA 2G6VA 3FL9A 1LY4A 4KYAA 3NU0A 4KD7A 5HQZA 2W3WA 2HM9A 1DF7A 1PDBA 4X5GA 3HJ3A 4KNEA 3S7AA 1S3WA 3F8ZA 1M79A 2OIPA 4FGHA 3NZCX 1YHOA 4P68A 3KJSA 1LUDA 3FS6A 4XT8A 3NZDA 1DG5A 5CC9A 3F0SX 2HQPA 3M09A 3HBBA 5E8QA 5HT4A 4M6JA 2AZNA 3GHCA 3FQFA 3FRFX 5DFRA 1PD9A 2DHFA 5ECXA 4IXED 1IA3A 4M6LA 2P4GA 3FYVX 1IA4A 4OR7A 2C2SA 4KM2A 4XECX 1PD8A 4HOGA 5HVBA 4XT6A 4FGGA 1CZ3A 4P66A 1MVSA 4CD2A 2FZHA 3S9UA 1S3YA 4M2XA 3RG9A 3EEKA 3NXTA 1DR3A 1RE7A 4H96A 3OCHA 4KLXA 1HFQA 3DRCA 3GHVA 1LY3A 4XT4A 5HT5A 3I3RA 1DREA 3K2HA 3TD8A 1JOLA 3M08A 2BLBA 2GD9A 3SQYX 1KMSA 1RA2A 1RC4A 4H97A 5CCCA 1KLKA 3DATA 4TU5X 3QYLA 4H98A 3JTWA 4IXGX 3FQZA 4ELFA 4KBNA 1BOZA 3FL8A 1RF7A 3D80A 3SRSX 3JWCA 1DRHA 1HFPA 2KGKA 4QI9A 3QYOA 1DG8A 4HOFA 2CIGA 1MVTA 4KJKA 3F0UX 3FRBX 1DR4A 3FQ0A 1DAJA 3D84X 4I1NA 3F0VX 2W3AA 4PSYA 3KY8A 3ZPCA 4P3QA 3JWKA 4KL9A 1J3JA 4ELBA 4Q67A 3NXXA 5JA3A 3DG8A 1BZFA 3FY9X 4KY8A 3TQAA 3IRMA 1DYRA 1AOEA 3QFXA 3VCOA 3TQ8A 3QLRA 1TDRA 1DDSA 3QL0A 4PSSA 3IA4A 3NXRA 3S3VA 1M7AA 1SEJA 3QLSA 1DRFA 4XT7A 3EEJA 2OBCA 4KJLA 3CD2A 1JOMA 3IROA 4PTHA 3F8YA 1RA1A 2W3MA 3NZ6X 3QLWA 4H95A 1J3IA 1RB3A 5ECCA 4X5JA 3JW3A 1S3UA 2DRCA 3FQOA 5HSUA 1DG7A 3DFRA 3KFYA 3UM8A 3FQVA 2XW7A 1RX7A 1IA2A 3UM6A 3RO9A 4PTJA 3CL9A 1E26A 5HVEA 3FREX 3NXOA 5HQYA 3EIGA 4NX7A 4EIGA 3F0BX 4LAEX 1RD7A 3NZBX 1RX9A 2D5NA 3EX8A 2BL9A 1VDRA 1DLRA 4GH8A 4LAGX 4PDJA 3QG2A 1RX1A 1IA1A 2ANOA 3GHWA 3K47A 3NRRA 5FDAA 4ELEA 3SAIA 3INVA 2W9TA 4G95A 4X5FA 4RGCA 4QJZD 4ELGA 3JSUA 3DAUA 3FRAX 1QZFA 3CLBA 4IXFX 5U27A 3UM5A 3NXVA 3CSEA 1RX2A 2C2TA 3F91A 5EAJA 3GYFA 4P3RA 1RX6A 2L28A 3K45A 3F0XX 4HOEA 3QLZA 1RA9A 1JUVA 3DL6A 3SR5X 4OSGA 4QLFA 2O7PA 4QLEA 3SA2A 3TQBA 1DYHA 3QGTA 4Q6AA 4Q0DA 1DHJA 3QLXA 1DR1A 3SRWX 2INQA 2H2QA 1DISA 3NZAX 1DYIA 4XE6X 4QLGA 4ELHA 1CD2A 4LAHX 4FHBA 1DRBA 1RB2A 2D0KA 1OHKA 3NTZA 3IX9A 4NX6A 3SRQX 1D1GA
chains in the Genus database with same CATH superfamily
3SRRX 3QL3A 3QLYA 4KFJA 4HA7A 5HI6A 4DPHA 2W3BA 2HXVA 2B3ZA 4DP3A 4LEKX 1RA8A 1RG7A 1RH3A 1RX3A 3NXYA 4M6KA 3FRDX 3JWFA 1RX8A 2JYBA 3KJRA 4EILA 2FZJA 3L3RA 4XT5A 3ZPGA 3EELA 5HUIA 2W3VA 2ZZAA 1DRAA 5HSRA 4KY4A 5JG0X 4KJJA 1KMVA 2QK8A 4QHVA 4QJCA 4KAKA 1DR7A 3Q1HA 2LF1A 1DDRA 3ROAA 1DR6A 1U72A 5U26A 3NZ9X 4KM0A 3IRNA 4G3MA 3JW5A 1DR5A 3KGYA 4EJ1A 4PSTA 4G8ZX 3OAFA 3SRUX 3E0BA 3DL5A 1DIUA 4KEBA 3SA1A 3DGAA 1HFRA 3LG4A 2BLCA 4X5IA 1OHJA 1U71A 4XRBA 1RA3A 3GI2A 4M7VA 3IA5A 1U70A 4X5HA 8DFRA 3N0HA 3EEMA 2ITHA 1RX5A 2W9GA 3JWMA 4ECKA 3R33A 2BLAA 5HF0X 3K74A 3I8AX 4DDRA 4DFRA 2W9SA 1AO8A 4HA9A 1DLSA 2FZIA 3SH2A 5DXVA 1VJ3A 2W9HA 7DFRA 3FYWX 1M78A 1DHFA 3FQCA 1J3KA 5HF2X 1ZDRA 4DPDA 3FY8X 1RX4A 4I13A 4M7UA 4Q0EA 3TQ9A 3F0QX 2CD2A 3SGYA 3JVXA 2ANQA 1DYJA 5HPBA 4EIZA 1AI9A 6DFRA 1S3VA 1DR2A 1DHIA 2G6VA 3FL9A 1LY4A 4KYAA 3NU0A 4KD7A 5HQZA 2W3WA 2HM9A 1DF7A 1PDBA 4X5GA 3HJ3A 4KNEA 3S7AA 1S3WA 3F8ZA 1M79A 2OIPA 4FGHA 3NZCX 1YHOA 4P68A 3KJSA 1LUDA 3FS6A 4XT8A 3NZDA 1DG5A 5CC9A 3F0SX 2HQPA 3M09A 3HBBA 5E8QA 5HT4A 4M6JA 2AZNA 3GHCA 3FQFA 3FRFX 5DFRA 1PD9A 2DHFA 5ECXA 4IXED 1IA3A 4M6LA 2P4GA 3FYVX 1IA4A 4OR7A 2C2SA 4KM2A 4XECX 1PD8A 4HOGA 5HVBA 4XT6A 4FGGA 1CZ3A 4P66A 1MVSA 4CD2A 2FZHA 3S9UA 1S3YA 4M2XA 3RG9A 3EEKA 3NXTA 1DR3A 1RE7A 4H96A 3OCHA 4KLXA 1HFQA 3DRCA 3GHVA 1LY3A 4XT4A 5HT5A 3I3RA 1DREA 3K2HA 3TD8A 1JOLA 3M08A 2BLBA 2GD9A 3SQYX 1KMSA 1RA2A 1RC4A 4H97A 5CCCA 1KLKA 3DATA 4TU5X 3QYLA 4H98A 3JTWA 4IXGX 3FQZA 4ELFA 4KBNA 1BOZA 3FL8A 1RF7A 3D80A 3SRSX 3JWCA 1DRHA 1HFPA 2KGKA 4QI9A 3QYOA 1DG8A 4HOFA 2CIGA 1MVTA 4KJKA 3F0UX 3FRBX 1DR4A 3FQ0A 1DAJA 3D84X 4I1NA 3F0VX 2W3AA 4PSYA 3KY8A 3ZPCA 4P3QA 3JWKA 4KL9A 1J3JA 4ELBA 4Q67A 3NXXA 5JA3A 3DG8A 1BZFA 3FY9X 4KY8A 3TQAA 3IRMA 1DYRA 1AOEA 3QFXA 3VCOA 3TQ8A 3QLRA 1TDRA 1DDSA 3QL0A 4PSSA 3IA4A 3NXRA 3S3VA 1M7AA 1SEJA 3QLSA 1DRFA 4XT7A 3EEJA 2OBCA 4KJLA 3CD2A 1JOMA 3IROA 4PTHA 3F8YA 1RA1A 2W3MA 3NZ6X 3QLWA 4H95A 1J3IA 1RB3A 5ECCA 4X5JA 3JW3A 1S3UA 2DRCA 3FQOA 5HSUA 1DG7A 3DFRA 3KFYA 3UM8A 3FQVA 2XW7A 1RX7A 1IA2A 3UM6A 3RO9A 4PTJA 3CL9A 1E26A 5HVEA 3FREX 3NXOA 5HQYA 3EIGA 4NX7A 4EIGA 3F0BX 4LAEX 1RD7A 3NZBX 1RX9A 2D5NA 3EX8A 2BL9A 1VDRA 1DLRA 4GH8A 4LAGX 4PDJA 3QG2A 1RX1A 1IA1A 2ANOA 3GHWA 3K47A 3NRRA 5FDAA 4ELEA 3SAIA 3INVA 2W9TA 4G95A 4X5FA 4RGCA 4QJZD 4ELGA 3JSUA 3DAUA 3FRAX 1QZFA 3CLBA 4IXFX 5U27A 3UM5A 3NXVA 3CSEA 1RX2A 2C2TA 3F91A 5EAJA 3GYFA 4P3RA 1RX6A 2L28A 3K45A 3F0XX 4HOEA 3QLZA 1RA9A 1JUVA 3DL6A 3SR5X 4OSGA 4QLFA 2O7PA 4QLEA 3SA2A 3TQBA 1DYHA 3QGTA 4Q6AA 4Q0DA 1DHJA 3QLXA 1DR1A 3SRWX 2INQA 2H2QA 1DISA 3NZAX 1DYIA 4XE6X 4QLGA 4ELHA 1CD2A 4LAHX 4FHBA 1DRBA 1RB2A 2D0KA 1OHKA 3NTZA 3IX9A 4NX6A 3SRQX 1D1GA
chains in the Genus database with same CATH topology
3SRRX 3QL3A 3QLYA 4KFJA 4HA7A 5HI6A 4DPHA 2W3BA 2HXVA 2B3ZA 4DP3A 4LEKX 1RA8A 1RG7A 1RH3A 1RX3A 3NXYA 4M6KA 3FRDX 3JWFA 1RX8A 2JYBA 3KJRA 4EILA 2FZJA 3L3RA 4XT5A 3ZPGA 3EELA 5HUIA 2W3VA 2ZZAA 1DRAA 5HSRA 4KY4A 5JG0X 4KJJA 1KMVA 2QK8A 4QHVA 4QJCA 4KAKA 1DR7A 3Q1HA 2LF1A 1DDRA 3ROAA 1DR6A 1U72A 5U26A 3NZ9X 4KM0A 3IRNA 4G3MA 3JW5A 1DR5A 3KGYA 4EJ1A 4PSTA 4G8ZX 3OAFA 3SRUX 3E0BA 3DL5A 1DIUA 4KEBA 3SA1A 3DGAA 1HFRA 3LG4A 2BLCA 4X5IA 1OHJA 1U71A 4XRBA 1RA3A 3GI2A 4M7VA 3IA5A 1U70A 4X5HA 8DFRA 3N0HA 3EEMA 2ITHA 1RX5A 2W9GA 3JWMA 4ECKA 3R33A 2BLAA 5HF0X 3K74A 3I8AX 4DDRA 4DFRA 2W9SA 1AO8A 4HA9A 1DLSA 2FZIA 3SH2A 5DXVA 1VJ3A 2W9HA 7DFRA 3FYWX 1M78A 1DHFA 3FQCA 1J3KA 5HF2X 1ZDRA 4DPDA 3FY8X 1RX4A 4I13A 4M7UA 4Q0EA 3TQ9A 3F0QX 2CD2A 3SGYA 3JVXA 2ANQA 1DYJA 5HPBA 4EIZA 1AI9A 6DFRA 1S3VA 1DR2A 1DHIA 2G6VA 3FL9A 1LY4A 4KYAA 3NU0A 4KD7A 5HQZA 2W3WA 2HM9A 1DF7A 1PDBA 4X5GA 3HJ3A 4KNEA 3S7AA 1S3WA 3F8ZA 1M79A 2OIPA 4FGHA 3NZCX 1YHOA 4P68A 3KJSA 1LUDA 3FS6A 4XT8A 3NZDA 1DG5A 5CC9A 3F0SX 2HQPA 3M09A 3HBBA 5E8QA 5HT4A 4M6JA 2AZNA 3GHCA 3FQFA 3FRFX 5DFRA 1PD9A 2DHFA 5ECXA 4IXED 1IA3A 4M6LA 2P4GA 3FYVX 1IA4A 4OR7A 2C2SA 4KM2A 4XECX 1PD8A 4HOGA 5HVBA 4XT6A 4FGGA 1CZ3A 4P66A 1MVSA 4CD2A 2FZHA 3S9UA 1S3YA 4M2XA 3RG9A 3EEKA 3NXTA 1DR3A 1RE7A 4H96A 3OCHA 4KLXA 1HFQA 3DRCA 3GHVA 1LY3A 4XT4A 5HT5A 3I3RA 1DREA 3K2HA 3TD8A 1JOLA 3M08A 2BLBA 2GD9A 3SQYX 1KMSA 1RA2A 1RC4A 4H97A 5CCCA 1KLKA 3DATA 4TU5X 3QYLA 4H98A 3JTWA 4IXGX 3FQZA 4ELFA 4KBNA 1BOZA 3FL8A 1RF7A 3D80A 3SRSX 3JWCA 1DRHA 1HFPA 2KGKA 4QI9A 3QYOA 1DG8A 4HOFA 2CIGA 1MVTA 4KJKA 3F0UX 3FRBX 1DR4A 3FQ0A 1DAJA 3D84X 4I1NA 3F0VX 2W3AA 4PSYA 3KY8A 3ZPCA 4P3QA 3JWKA 4KL9A 1J3JA 4ELBA 4Q67A 3NXXA 5JA3A 3DG8A 1BZFA 3FY9X 4KY8A 3TQAA 3IRMA 1DYRA 1AOEA 3QFXA 3VCOA 3TQ8A 3QLRA 1TDRA 1DDSA 3QL0A 4PSSA 3IA4A 3NXRA 3S3VA 1M7AA 1SEJA 3QLSA 1DRFA 4XT7A 3EEJA 2OBCA 4KJLA 3CD2A 1JOMA 3IROA 4PTHA 3F8YA 1RA1A 2W3MA 3NZ6X 3QLWA 4H95A 1J3IA 1RB3A 5ECCA 4X5JA 3JW3A 1S3UA 2DRCA 3FQOA 5HSUA 1DG7A 3DFRA 3KFYA 3UM8A 3FQVA 2XW7A 1RX7A 1IA2A 3UM6A 3RO9A 4PTJA 3CL9A 1E26A 5HVEA 3FREX 3NXOA 5HQYA 3EIGA 4NX7A 4EIGA 3F0BX 4LAEX 1RD7A 3NZBX 1RX9A 2D5NA 3EX8A 2BL9A 1VDRA 1DLRA 4GH8A 4LAGX 4PDJA 3QG2A 1RX1A 1IA1A 2ANOA 3GHWA 3K47A 3NRRA 5FDAA 4ELEA 3SAIA 3INVA 2W9TA 4G95A 4X5FA 4RGCA 4QJZD 4ELGA 3JSUA 3DAUA 3FRAX 1QZFA 3CLBA 4IXFX 5U27A 3UM5A 3NXVA 3CSEA 1RX2A 2C2TA 3F91A 5EAJA 3GYFA 4P3RA 1RX6A 2L28A 3K45A 3F0XX 4HOEA 3QLZA 1RA9A 1JUVA 3DL6A 3SR5X 4OSGA 4QLFA 2O7PA 4QLEA 3SA2A 3TQBA 1DYHA 3QGTA 4Q6AA 4Q0DA 1DHJA 3QLXA 1DR1A 3SRWX 2INQA 2H2QA 1DISA 3NZAX 1DYIA 4XE6X 4QLGA 4ELHA 1CD2A 4LAHX 4FHBA 1DRBA 1RB2A 2D0KA 1OHKA 3NTZA 3IX9A 4NX6A 3SRQX 1D1GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SRR X;  3QL3 A;  3QLY A;  4KFJ A;  4HA7 A;  5HI6 A;  4DPH A;  2W3B A;  2HXV A;  2B3Z A;  4DP3 A;  4LEK X;  1RA8 A;  1RG7 A;  1RH3 A;  1RX3 A;  3NXY A;  4M6K A;  3FRD X;  3JWF A;  1RX8 A;  2JYB A;  3KJR A;  4EIL A;  2FZJ A;  3L3R A;  4XT5 A;  3ZPG A;  3EEL A;  5HUI A;  2W3V A;  2ZZA A;  1DRA A;  5HSR A;  4KY4 A;  5JG0 X;  4KJJ A;  1KMV A;  2QK8 A;  4QHV A;  4QJC A;  4KAK A;  1DR7 A;  3Q1H A;  2LF1 A;  1DDR A;  3ROA A;  1DR6 A;  1U72 A;  5U26 A;  3NZ9 X;  4KM0 A;  3IRN A;  4G3M A;  3JW5 A;  1DR5 A;  3KGY A;  4EJ1 A;  4PST A;  4G8Z X;  3OAF A;  3SRU X;  3E0B A;  3DL5 A;  1DIU A;  4KEB A;  3SA1 A;  3DGA A;  1HFR A;  3LG4 A;  2BLC A;  4X5I A;  1OHJ A;  1U71 A;  4XRB A;  1RA3 A;  3GI2 A;  4M7V A;  3IA5 A;  1U70 A;  4X5H A;  8DFR A;  3N0H A;  3EEM A;  2ITH A;  1RX5 A;  2W9G A;  3JWM A;  4ECK A;  3R33 A;  2BLA A;  5HF0 X;  3K74 A;  3I8A X;  4DDR A;  4DFR A;  2W9S A;  1AO8 A;  4HA9 A;  1DLS A;  2FZI A;  3SH2 A;  5DXV A;  1VJ3 A;  2W9H A;  7DFR A;  3FYW X;  1M78 A;  1DHF A;  3FQC A;  1J3K A;  5HF2 X;  1ZDR A;  4DPD A;  3FY8 X;  1RX4 A;  4I13 A;  4M7U A;  4Q0E A;  3TQ9 A;  3F0Q X;  2CD2 A;  3SGY A;  3JVX A;  2ANQ A;  1DYJ A;  5HPB A;  4EIZ A;  1AI9 A;  6DFR A;  1S3V A;  1DR2 A;  1DHI A;  2G6V A;  3FL9 A;  1LY4 A;  4KYA A;  3NU0 A;  4KD7 A;  5HQZ A;  2W3W A;  2HM9 A;  1DF7 A;  1PDB A;  4X5G A;  3HJ3 A;  4KNE A;  3S7A A;  1S3W A;  3F8Z A;  1M79 A;  2OIP A;  4FGH A;  3NZC X;  1YHO A;  4P68 A;  3KJS A;  1LUD A;  3FS6 A;  4XT8 A;  3NZD A;  1DG5 A;  5CC9 A;  3F0S X;  2HQP A;  3M09 A;  3HBB A;  5E8Q A;  5HT4 A;  4M6J A;  2AZN A;  3GHC A;  3FQF A;  3FRF X;  5DFR A;  1PD9 A;  2DHF A;  5ECX A;  4IXE D;  1IA3 A;  4M6L A;  2P4G A;  3FYV X;  1IA4 A;  4OR7 A;  2C2S A;  4KM2 A;  4XEC X;  1PD8 A;  4HOG A;  5HVB A;  4XT6 A;  4FGG A;  1CZ3 A;  4P66 A;  1MVS A;  4CD2 A;  2FZH A;  3S9U A;  1S3Y A;  4M2X A;  3RG9 A;  3EEK A;  3NXT A;  1DR3 A;  1RE7 A;  4H96 A;  3OCH A;  4KLX A;  1HFQ A;  3DRC A;  3GHV A;  1LY3 A;  4XT4 A;  5HT5 A;  3I3R A;  1DRE A;  3K2H A;  3TD8 A;  1JOL A;  3M08 A;  2BLB A;  2GD9 A;  3SQY X;  1KMS A;  1RA2 A;  1RC4 A;  4H97 A;  5CCC A;  1KLK A;  3DAT A;  4TU5 X;  3QYL A;  4H98 A;  3JTW A;  4IXG X;  3FQZ A;  4ELF A;  4KBN A;  1BOZ A;  3FL8 A;  1RF7 A;  3D80 A;  3SRS X;  3JWC A;  1DRH A;  1HFP A;  2KGK A;  4QI9 A;  3QYO A;  1DG8 A;  4HOF A;  2CIG A;  1MVT A;  4KJK A;  3F0U X;  3FRB X;  1DR4 A;  3FQ0 A;  1DAJ A;  3D84 X;  4I1N A;  3F0V X;  2W3A A;  4PSY A;  3KY8 A;  3ZPC A;  4P3Q A;  3JWK A;  4KL9 A;  1J3J A;  4ELB A;  4Q67 A;  3NXX A;  5JA3 A;  3DG8 A;  1BZF A;  3FY9 X;  4KY8 A;  3TQA A;  3IRM A;  1DYR A;  1AOE A;  3QFX A;  3VCO A;  3TQ8 A;  3QLR A;  1TDR A;  1DDS A;  3QL0 A;  4PSS A;  3IA4 A;  3NXR A;  3S3V A;  1M7A A;  1SEJ A;  3QLS A;  1DRF A;  4XT7 A;  3EEJ A;  2OBC A;  4KJL A;  3CD2 A;  1JOM A;  3IRO A;  4PTH A;  3F8Y A;  1RA1 A;  2W3M A;  3NZ6 X;  3QLW A;  4H95 A;  1J3I A;  1RB3 A;  5ECC A;  4X5J A;  3JW3 A;  1S3U A;  2DRC A;  3FQO A;  5HSU A;  1DG7 A;  3DFR A;  3KFY A;  3UM8 A;  3FQV A;  2XW7 A;  1RX7 A;  1IA2 A;  3UM6 A;  3RO9 A;  4PTJ A;  3CL9 A;  1E26 A;  5HVE A;  3FRE X;  3NXO A;  5HQY A;  3EIG A;  4NX7 A;  4EIG A;  3F0B X;  4LAE X;  1RD7 A;  3NZB X;  1RX9 A;  2D5N A;  3EX8 A;  2BL9 A;  1VDR A;  1DLR A;  4GH8 A;  4LAG X;  4PDJ A;  3QG2 A;  1RX1 A;  1IA1 A;  2ANO A;  3GHW A;  3K47 A;  3NRR A;  5FDA A;  4ELE A;  3SAI A;  3INV A;  2W9T A;  4G95 A;  4X5F A;  4RGC A;  4QJZ D;  4ELG A;  3JSU A;  3DAU A;  3FRA X;  1QZF A;  3CLB A;  4IXF X;  5U27 A;  3UM5 A;  3NXV A;  3CSE A;  1RX2 A;  2C2T A;  3F91 A;  5EAJ A;  3GYF A;  4P3R A;  1RX6 A;  2L28 A;  3K45 A;  3F0X X;  4HOE A;  3QLZ A;  1RA9 A;  1JUV A;  3DL6 A;  3SR5 X;  4OSG A;  4QLF A;  2O7P A;  4QLE A;  3SA2 A;  3TQB A;  1DYH A;  3QGT A;  4Q6A A;  4Q0D A;  1DHJ A;  3QLX A;  1DR1 A;  3SRW X;  2INQ A;  2H2Q A;  1DIS A;  3NZA X;  1DYI A;  4XE6 X;  4QLG A;  4ELH A;  1CD2 A;  4LAH X;  4FHB A;  1DRB A;  1RB2 A;  2D0K A;  1OHK A;  3NTZ A;  3IX9 A;  4NX6 A;  3SRQ X;  1D1G A; 
#chains in the Genus database with same CATH topology
 3SRR X;  3QL3 A;  3QLY A;  4KFJ A;  4HA7 A;  5HI6 A;  4DPH A;  2W3B A;  2HXV A;  2B3Z A;  4DP3 A;  4LEK X;  1RA8 A;  1RG7 A;  1RH3 A;  1RX3 A;  3NXY A;  4M6K A;  3FRD X;  3JWF A;  1RX8 A;  2JYB A;  3KJR A;  4EIL A;  2FZJ A;  3L3R A;  4XT5 A;  3ZPG A;  3EEL A;  5HUI A;  2W3V A;  2ZZA A;  1DRA A;  5HSR A;  4KY4 A;  5JG0 X;  4KJJ A;  1KMV A;  2QK8 A;  4QHV A;  4QJC A;  4KAK A;  1DR7 A;  3Q1H A;  2LF1 A;  1DDR A;  3ROA A;  1DR6 A;  1U72 A;  5U26 A;  3NZ9 X;  4KM0 A;  3IRN A;  4G3M A;  3JW5 A;  1DR5 A;  3KGY A;  4EJ1 A;  4PST A;  4G8Z X;  3OAF A;  3SRU X;  3E0B A;  3DL5 A;  1DIU A;  4KEB A;  3SA1 A;  3DGA A;  1HFR A;  3LG4 A;  2BLC A;  4X5I A;  1OHJ A;  1U71 A;  4XRB A;  1RA3 A;  3GI2 A;  4M7V A;  3IA5 A;  1U70 A;  4X5H A;  8DFR A;  3N0H A;  3EEM A;  2ITH A;  1RX5 A;  2W9G A;  3JWM A;  4ECK A;  3R33 A;  2BLA A;  5HF0 X;  3K74 A;  3I8A X;  4DDR A;  4DFR A;  2W9S A;  1AO8 A;  4HA9 A;  1DLS A;  2FZI A;  3SH2 A;  5DXV A;  1VJ3 A;  2W9H A;  7DFR A;  3FYW X;  1M78 A;  1DHF A;  3FQC A;  1J3K A;  5HF2 X;  1ZDR A;  4DPD A;  3FY8 X;  1RX4 A;  4I13 A;  4M7U A;  4Q0E A;  3TQ9 A;  3F0Q X;  2CD2 A;  3SGY A;  3JVX A;  2ANQ A;  1DYJ A;  5HPB A;  4EIZ A;  1AI9 A;  6DFR A;  1S3V A;  1DR2 A;  1DHI A;  2G6V A;  3FL9 A;  1LY4 A;  4KYA A;  3NU0 A;  4KD7 A;  5HQZ A;  2W3W A;  2HM9 A;  1DF7 A;  1PDB A;  4X5G A;  3HJ3 A;  4KNE A;  3S7A A;  1S3W A;  3F8Z A;  1M79 A;  2OIP A;  4FGH A;  3NZC X;  1YHO A;  4P68 A;  3KJS A;  1LUD A;  3FS6 A;  4XT8 A;  3NZD A;  1DG5 A;  5CC9 A;  3F0S X;  2HQP A;  3M09 A;  3HBB A;  5E8Q A;  5HT4 A;  4M6J A;  2AZN A;  3GHC A;  3FQF A;  3FRF X;  5DFR A;  1PD9 A;  2DHF A;  5ECX A;  4IXE D;  1IA3 A;  4M6L A;  2P4G A;  3FYV X;  1IA4 A;  4OR7 A;  2C2S A;  4KM2 A;  4XEC X;  1PD8 A;  4HOG A;  5HVB A;  4XT6 A;  4FGG A;  1CZ3 A;  4P66 A;  1MVS A;  4CD2 A;  2FZH A;  3S9U A;  1S3Y A;  4M2X A;  3RG9 A;  3EEK A;  3NXT A;  1DR3 A;  1RE7 A;  4H96 A;  3OCH A;  4KLX A;  1HFQ A;  3DRC A;  3GHV A;  1LY3 A;  4XT4 A;  5HT5 A;  3I3R A;  1DRE A;  3K2H A;  3TD8 A;  1JOL A;  3M08 A;  2BLB A;  2GD9 A;  3SQY X;  1KMS A;  1RA2 A;  1RC4 A;  4H97 A;  5CCC A;  1KLK A;  3DAT A;  4TU5 X;  3QYL A;  4H98 A;  3JTW A;  4IXG X;  3FQZ A;  4ELF A;  4KBN A;  1BOZ A;  3FL8 A;  1RF7 A;  3D80 A;  3SRS X;  3JWC A;  1DRH A;  1HFP A;  2KGK A;  4QI9 A;  3QYO A;  1DG8 A;  4HOF A;  2CIG A;  1MVT A;  4KJK A;  3F0U X;  3FRB X;  1DR4 A;  3FQ0 A;  1DAJ A;  3D84 X;  4I1N A;  3F0V X;  2W3A A;  4PSY A;  3KY8 A;  3ZPC A;  4P3Q A;  3JWK A;  4KL9 A;  1J3J A;  4ELB A;  4Q67 A;  3NXX A;  5JA3 A;  3DG8 A;  1BZF A;  3FY9 X;  4KY8 A;  3TQA A;  3IRM A;  1DYR A;  1AOE A;  3QFX A;  3VCO A;  3TQ8 A;  3QLR A;  1TDR A;  1DDS A;  3QL0 A;  4PSS A;  3IA4 A;  3NXR A;  3S3V A;  1M7A A;  1SEJ A;  3QLS A;  1DRF A;  4XT7 A;  3EEJ A;  2OBC A;  4KJL A;  3CD2 A;  1JOM A;  3IRO A;  4PTH A;  3F8Y A;  1RA1 A;  2W3M A;  3NZ6 X;  3QLW A;  4H95 A;  1J3I A;  1RB3 A;  5ECC A;  4X5J A;  3JW3 A;  1S3U A;  2DRC A;  3FQO A;  5HSU A;  1DG7 A;  3DFR A;  3KFY A;  3UM8 A;  3FQV A;  2XW7 A;  1RX7 A;  1IA2 A;  3UM6 A;  3RO9 A;  4PTJ A;  3CL9 A;  1E26 A;  5HVE A;  3FRE X;  3NXO A;  5HQY A;  3EIG A;  4NX7 A;  4EIG A;  3F0B X;  4LAE X;  1RD7 A;  3NZB X;  1RX9 A;  2D5N A;  3EX8 A;  2BL9 A;  1VDR A;  1DLR A;  4GH8 A;  4LAG X;  4PDJ A;  3QG2 A;  1RX1 A;  1IA1 A;  2ANO A;  3GHW A;  3K47 A;  3NRR A;  5FDA A;  4ELE A;  3SAI A;  3INV A;  2W9T A;  4G95 A;  4X5F A;  4RGC A;  4QJZ D;  4ELG A;  3JSU A;  3DAU A;  3FRA X;  1QZF A;  3CLB A;  4IXF X;  5U27 A;  3UM5 A;  3NXV A;  3CSE A;  1RX2 A;  2C2T A;  3F91 A;  5EAJ A;  3GYF A;  4P3R A;  1RX6 A;  2L28 A;  3K45 A;  3F0X X;  4HOE A;  3QLZ A;  1RA9 A;  1JUV A;  3DL6 A;  3SR5 X;  4OSG A;  4QLF A;  2O7P A;  4QLE A;  3SA2 A;  3TQB A;  1DYH A;  3QGT A;  4Q6A A;  4Q0D A;  1DHJ A;  3QLX A;  1DR1 A;  3SRW X;  2INQ A;  2H2Q A;  1DIS A;  3NZA X;  1DYI A;  4XE6 X;  4QLG A;  4ELH A;  1CD2 A;  4LAH X;  4FHB A;  1DRB A;  1RB2 A;  2D0K A;  1OHK A;  3NTZ A;  3IX9 A;  4NX6 A;  3SRQ X;  1D1G A; 
#chains in the Genus database with same CATH homology
 3SRR X;  3QL3 A;  3QLY A;  4KFJ A;  4HA7 A;  5HI6 A;  4DPH A;  2W3B A;  2HXV A;  2B3Z A;  4DP3 A;  4LEK X;  1RA8 A;  1RG7 A;  1RH3 A;  1RX3 A;  3NXY A;  4M6K A;  3FRD X;  3JWF A;  1RX8 A;  2JYB A;  3KJR A;  4EIL A;  2FZJ A;  3L3R A;  4XT5 A;  3ZPG A;  3EEL A;  5HUI A;  2W3V A;  2ZZA A;  1DRA A;  5HSR A;  4KY4 A;  5JG0 X;  4KJJ A;  1KMV A;  2QK8 A;  4QHV A;  4QJC A;  4KAK A;  1DR7 A;  3Q1H A;  2LF1 A;  1DDR A;  3ROA A;  1DR6 A;  1U72 A;  5U26 A;  3NZ9 X;  4KM0 A;  3IRN A;  4G3M A;  3JW5 A;  1DR5 A;  3KGY A;  4EJ1 A;  4PST A;  4G8Z X;  3OAF A;  3SRU X;  3E0B A;  3DL5 A;  1DIU A;  4KEB A;  3SA1 A;  3DGA A;  1HFR A;  3LG4 A;  2BLC A;  4X5I A;  1OHJ A;  1U71 A;  4XRB A;  1RA3 A;  3GI2 A;  4M7V A;  3IA5 A;  1U70 A;  4X5H A;  8DFR A;  3N0H A;  3EEM A;  2ITH A;  1RX5 A;  2W9G A;  3JWM A;  4ECK A;  3R33 A;  2BLA A;  5HF0 X;  3K74 A;  3I8A X;  4DDR A;  4DFR A;  2W9S A;  1AO8 A;  4HA9 A;  1DLS A;  2FZI A;  3SH2 A;  5DXV A;  1VJ3 A;  2W9H A;  7DFR A;  3FYW X;  1M78 A;  1DHF A;  3FQC A;  1J3K A;  5HF2 X;  1ZDR A;  4DPD A;  3FY8 X;  1RX4 A;  4I13 A;  4M7U A;  4Q0E A;  3TQ9 A;  3F0Q X;  2CD2 A;  3SGY A;  3JVX A;  2ANQ A;  1DYJ A;  5HPB A;  4EIZ A;  1AI9 A;  6DFR A;  1S3V A;  1DR2 A;  1DHI A;  2G6V A;  3FL9 A;  1LY4 A;  4KYA A;  3NU0 A;  4KD7 A;  5HQZ A;  2W3W A;  2HM9 A;  1DF7 A;  1PDB A;  4X5G A;  3HJ3 A;  4KNE A;  3S7A A;  1S3W A;  3F8Z A;  1M79 A;  2OIP A;  4FGH A;  3NZC X;  1YHO A;  4P68 A;  3KJS A;  1LUD A;  3FS6 A;  4XT8 A;  3NZD A;  1DG5 A;  5CC9 A;  3F0S X;  2HQP A;  3M09 A;  3HBB A;  5E8Q A;  5HT4 A;  4M6J A;  2AZN A;  3GHC A;  3FQF A;  3FRF X;  5DFR A;  1PD9 A;  2DHF A;  5ECX A;  4IXE D;  1IA3 A;  4M6L A;  2P4G A;  3FYV X;  1IA4 A;  4OR7 A;  2C2S A;  4KM2 A;  4XEC X;  1PD8 A;  4HOG A;  5HVB A;  4XT6 A;  4FGG A;  1CZ3 A;  4P66 A;  1MVS A;  4CD2 A;  2FZH A;  3S9U A;  1S3Y A;  4M2X A;  3RG9 A;  3EEK A;  3NXT A;  1DR3 A;  1RE7 A;  4H96 A;  3OCH A;  4KLX A;  1HFQ A;  3DRC A;  3GHV A;  1LY3 A;  4XT4 A;  5HT5 A;  3I3R A;  1DRE A;  3K2H A;  3TD8 A;  1JOL A;  3M08 A;  2BLB A;  2GD9 A;  3SQY X;  1KMS A;  1RA2 A;  1RC4 A;  4H97 A;  5CCC A;  1KLK A;  3DAT A;  4TU5 X;  3QYL A;  4H98 A;  3JTW A;  4IXG X;  3FQZ A;  4ELF A;  4KBN A;  1BOZ A;  3FL8 A;  1RF7 A;  3D80 A;  3SRS X;  3JWC A;  1DRH A;  1HFP A;  2KGK A;  4QI9 A;  3QYO A;  1DG8 A;  4HOF A;  2CIG A;  1MVT A;  4KJK A;  3F0U X;  3FRB X;  1DR4 A;  3FQ0 A;  1DAJ A;  3D84 X;  4I1N A;  3F0V X;  2W3A A;  4PSY A;  3KY8 A;  3ZPC A;  4P3Q A;  3JWK A;  4KL9 A;  1J3J A;  4ELB A;  4Q67 A;  3NXX A;  5JA3 A;  3DG8 A;  1BZF A;  3FY9 X;  4KY8 A;  3TQA A;  3IRM A;  1DYR A;  1AOE A;  3QFX A;  3VCO A;  3TQ8 A;  3QLR A;  1TDR A;  1DDS A;  3QL0 A;  4PSS A;  3IA4 A;  3NXR A;  3S3V A;  1M7A A;  1SEJ A;  3QLS A;  1DRF A;  4XT7 A;  3EEJ A;  2OBC A;  4KJL A;  3CD2 A;  1JOM A;  3IRO A;  4PTH A;  3F8Y A;  1RA1 A;  2W3M A;  3NZ6 X;  3QLW A;  4H95 A;  1J3I A;  1RB3 A;  5ECC A;  4X5J A;  3JW3 A;  1S3U A;  2DRC A;  3FQO A;  5HSU A;  1DG7 A;  3DFR A;  3KFY A;  3UM8 A;  3FQV A;  2XW7 A;  1RX7 A;  1IA2 A;  3UM6 A;  3RO9 A;  4PTJ A;  3CL9 A;  1E26 A;  5HVE A;  3FRE X;  3NXO A;  5HQY A;  3EIG A;  4NX7 A;  4EIG A;  3F0B X;  4LAE X;  1RD7 A;  3NZB X;  1RX9 A;  2D5N A;  3EX8 A;  2BL9 A;  1VDR A;  1DLR A;  4GH8 A;  4LAG X;  4PDJ A;  3QG2 A;  1RX1 A;  1IA1 A;  2ANO A;  3GHW A;  3K47 A;  3NRR A;  5FDA A;  4ELE A;  3SAI A;  3INV A;  2W9T A;  4G95 A;  4X5F A;  4RGC A;  4QJZ D;  4ELG A;  3JSU A;  3DAU A;  3FRA X;  1QZF A;  3CLB A;  4IXF X;  5U27 A;  3UM5 A;  3NXV A;  3CSE A;  1RX2 A;  2C2T A;  3F91 A;  5EAJ A;  3GYF A;  4P3R A;  1RX6 A;  2L28 A;  3K45 A;  3F0X X;  4HOE A;  3QLZ A;  1RA9 A;  1JUV A;  3DL6 A;  3SR5 X;  4OSG A;  4QLF A;  2O7P A;  4QLE A;  3SA2 A;  3TQB A;  1DYH A;  3QGT A;  4Q6A A;  4Q0D A;  1DHJ A;  3QLX A;  1DR1 A;  3SRW X;  2INQ A;  2H2Q A;  1DIS A;  3NZA X;  1DYI A;  4XE6 X;  4QLG A;  4ELH A;  1CD2 A;  4LAH X;  4FHB A;  1DRB A;  1RB2 A;  2D0K A;  1OHK A;  3NTZ A;  3IX9 A;  4NX6 A;  3SRQ X;  1D1G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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