3SQYX

S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Staphylococcus aureus
molecule keywords Dihydrofolate reductase
total genus 41
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2011-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3sqyX00
3JWMA 1DYRA 1S3WA 1HFQA 4PSYA 2BLBA 3GHCA 3NU0A 3IRNA 5U27A 5HI6A 3CD2A 1SEJA 2O7PA 2ZZAA 4H95A 4KEBA 1AOEA 4EJ1A 3K74A 3FY8X 1MVSA 5FDAA 3UM8A 2OBCA 4KJJA 3JSUA 1OHKA 3E0BA 2C2SA 3FRBX 2DRCA 3VCOA 2FZJA 4I1NA 4M7UA 1DDSA 3FREX 1S3YA 3FRAX 5ECCA 3S3VA 4I13A 2D5NA 1RX6A 4HOFA 1ZDRA 3NXYA 3FQCA 1DR5A 1RA1A 3LG4A 3KJRA 3GYFA 1M79A 3FQ0A 4XE6X 3UM5A 5HQZA 4TU5X 4X5HA 3NXVA 1DRFA 2W3MA 5HT4A 3IROA 2BLCA 4Q0DA 1S3UA 1LUDA 4RGCA 5HQYA 1JOLA 3JWKA 3NTZA 1MVTA 3N0HA 4ELBA 1OHJA 1J3IA 4KJLA 3KJSA 3IX9A 4NX7A 3TQAA 2QK8A 4G3MA 2W3AA 3FS6A 3DATA 1BZFA 5HUIA 3CSEA 3JW5A 3I8AX 4EIGA 3NZAX 1J3KA 1U72A 1AO8A 3TQ9A 1IA3A 1RX1A 4H97A 2JYBA 3HJ3A 1RF7A 1DAJA 3DRCA 4LEKX 4PTJA 1DRBA 3DGAA 2LF1A 4FHBA 4ELFA 2B3ZA 4KLXA 1DDRA 1RB3A 4Q6AA 3FQFA 4DPDA 1DR2A 5U26A 4CD2A 3NXXA 3NXRA 1RX2A 1RG7A 3QGTA 3NXTA 1KMVA 4M6JA 1RE7A 5CC9A 1RX9A 3QLWA 2G6VA 4KD7A 5ECXA 3DL6A 1CZ3A 3QFXA 2GD9A 4DFRA 4EILA 4QJZD 4H98A 1RD7A 3QYLA 4X5JA 4ECKA 4DP3A 4EIZA 4ELEA 2W9TA 4P68A 1U70A 1BOZA 1DLRA 3KFYA 4OR7A 1E26A 3S9UA 3FQZA 4XT8A 4KFJA 1M7AA 4G8ZX 4KM2A 1DR7A 1RX4A 3K45A 3ZPCA 3F0QX 3QLZA 1KLKA 2XW7A 3F0XX 4PSSA 5JA3A 1QZFA 4X5GA 4HA9A 3GHVA 3CL9A 1DRAA 1DYJA 4PDJA 1J3JA 3F8ZA 4QI9A 1DR4A 3EX8A 1S3VA 3SA1A 2W9HA 3SQYX 6DFRA 1DIUA 5HF2X 7DFRA 2ANOA 4G95A 3D84X 3HBBA 3K47A 1RC4A 3INVA 4KAKA 3EEJA 4Q0EA 2KGKA 8DFRA 1PD9A 3F0BX 3F0VX 3DG8A 1M78A 2HXVA 4QJCA 1AI9A 1DHFA 1DISA 3S7AA 1DR3A 1DR6A 3RG9A 4KBNA 3EEMA 3QYOA 1IA4A 3F8YA 4IXFX 3TD8A 3K2HA 3SRSX 3SRWX 2BL9A 5CCCA 1PD8A 3EELA 3QLSA 4X5IA 1LY4A 5EAJA 4QLGA 5DFRA 1KMSA 4HOEA 1HFRA 2ITHA 1RB2A 4IXED 3CLBA 5HSRA 4PSTA 3QLYA 3IA5A 4M6KA 1HFPA 3TQ8A 4M6LA 1DG8A 4Q67A 3UM6A 4HOGA 1RX3A 3F0SX 2HQPA 3FL9A 3M08A 4P66A 3TQBA 4IXGX 3R33A 3JVXA 1YHOA 5HF0X 1DF7A 1DHIA 4KYAA 4XT7A 3JWFA 1DR1A 5E8QA 3FY9X 2ANQA 1DYIA 1JUVA 2FZHA 2INQA 4HA7A 1DG7A 4GH8A 3SGYA 1RX5A 3QL3A 3NZ6X 3D80A 1U71A 3FYVX 2OIPA 3Q1HA 3NZ9X 5HSUA 4M7VA 3SAIA 2AZNA 2CIGA 3F0UX 1LY3A 4XT5A 2CD2A 3NZCX 4X5FA 4KJKA 3SRUX 4QHVA 4NX6A 3DL5A 3I3RA 1RA2A 3L3RA 2BLAA 2L28A 4KL9A 4DDRA 3NXOA 4KY8A 3QLRA 1PDBA 4KNEA 4FGHA 4LAHX 3FYWX 4KY4A 2H2QA 4LAEX 2C2TA 4H96A 1DG5A 3IA4A 3GI2A 3KY8A 1RX8A 1RX7A 1TDRA 2W9SA 4ELGA 3EEKA 3EIGA 3QL0A 5JG0X 3IRMA 3DAUA 3NRRA 1RA9A 4KM0A 3FQOA 3DFRA 4XRBA 4OSGA 1IA1A 3JWCA 2HM9A 4P3RA 3M09A 4QLEA 1DREA 3NZDA 4DPHA 3FRDX 2DHFA 5HVEA 2W3WA 1CD2A 3ROAA 4XT4A 2FZIA 1D1GA 1DRHA 4FGGA 2P4GA 4LAGX 1JOMA 4PTHA 5HPBA 1VJ3A 2W9GA 3SR5X 3SH2A 3GHWA 3FL8A 5HT5A 1RH3A 2W3VA 5DXVA 3FQVA 3RO9A 3ZPGA 1RA3A 3OCHA 3NZBX 4P3QA 4ELHA 1IA2A 3SA2A 1DLSA 4M2XA 1RA8A 3JTWA 3KGYA 3QG2A 4XT6A 3SRQX 1VDRA 3SRRX 2W3BA 2D0KA 3F91A 5HVBA 3OAFA 3FRFX 1DYHA 3JW3A 4QLFA 3QLXA 4XECX 1DHJA
chains in the Genus database with same CATH superfamily
3JWMA 1DYRA 1S3WA 1HFQA 4PSYA 2BLBA 3GHCA 3NU0A 3IRNA 5U27A 5HI6A 3CD2A 1SEJA 2O7PA 2ZZAA 4H95A 4KEBA 1AOEA 4EJ1A 3K74A 3FY8X 1MVSA 5FDAA 3UM8A 2OBCA 4KJJA 3JSUA 1OHKA 3E0BA 2C2SA 3FRBX 2DRCA 3VCOA 2FZJA 4I1NA 4M7UA 1DDSA 3FREX 1S3YA 3FRAX 5ECCA 3S3VA 4I13A 2D5NA 1RX6A 4HOFA 1ZDRA 3NXYA 3FQCA 1DR5A 1RA1A 3LG4A 3KJRA 3GYFA 1M79A 3FQ0A 4XE6X 3UM5A 5HQZA 4TU5X 4X5HA 3NXVA 1DRFA 2W3MA 5HT4A 3IROA 2BLCA 4Q0DA 1S3UA 1LUDA 4RGCA 5HQYA 1JOLA 3JWKA 3NTZA 1MVTA 3N0HA 4ELBA 1OHJA 1J3IA 4KJLA 3KJSA 3IX9A 4NX7A 3TQAA 2QK8A 4G3MA 2W3AA 3FS6A 3DATA 1BZFA 5HUIA 3CSEA 3JW5A 3I8AX 4EIGA 3NZAX 1J3KA 1U72A 1AO8A 3TQ9A 1IA3A 1RX1A 4H97A 2JYBA 3HJ3A 1RF7A 1DAJA 3DRCA 4LEKX 4PTJA 1DRBA 3DGAA 2LF1A 4FHBA 4ELFA 2B3ZA 4KLXA 1DDRA 1RB3A 4Q6AA 3FQFA 4DPDA 1DR2A 5U26A 4CD2A 3NXXA 3NXRA 1RX2A 1RG7A 3QGTA 3NXTA 1KMVA 4M6JA 1RE7A 5CC9A 1RX9A 3QLWA 2G6VA 4KD7A 5ECXA 3DL6A 1CZ3A 3QFXA 2GD9A 4DFRA 4EILA 4QJZD 4H98A 1RD7A 3QYLA 4X5JA 4ECKA 4DP3A 4EIZA 4ELEA 2W9TA 4P68A 1U70A 1BOZA 1DLRA 3KFYA 4OR7A 1E26A 3S9UA 3FQZA 4XT8A 4KFJA 1M7AA 4G8ZX 4KM2A 1DR7A 1RX4A 3K45A 3ZPCA 3F0QX 3QLZA 1KLKA 2XW7A 3F0XX 4PSSA 5JA3A 1QZFA 4X5GA 4HA9A 3GHVA 3CL9A 1DRAA 1DYJA 4PDJA 1J3JA 3F8ZA 4QI9A 1DR4A 3EX8A 1S3VA 3SA1A 2W9HA 3SQYX 6DFRA 1DIUA 5HF2X 7DFRA 2ANOA 4G95A 3D84X 3HBBA 3K47A 1RC4A 3INVA 4KAKA 3EEJA 4Q0EA 2KGKA 8DFRA 1PD9A 3F0BX 3F0VX 3DG8A 1M78A 2HXVA 4QJCA 1AI9A 1DHFA 1DISA 3S7AA 1DR3A 1DR6A 3RG9A 4KBNA 3EEMA 3QYOA 1IA4A 3F8YA 4IXFX 3TD8A 3K2HA 3SRSX 3SRWX 2BL9A 5CCCA 1PD8A 3EELA 3QLSA 4X5IA 1LY4A 5EAJA 4QLGA 5DFRA 1KMSA 4HOEA 1HFRA 2ITHA 1RB2A 4IXED 3CLBA 5HSRA 4PSTA 3QLYA 3IA5A 4M6KA 1HFPA 3TQ8A 4M6LA 1DG8A 4Q67A 3UM6A 4HOGA 1RX3A 3F0SX 2HQPA 3FL9A 3M08A 4P66A 3TQBA 4IXGX 3R33A 3JVXA 1YHOA 5HF0X 1DF7A 1DHIA 4KYAA 4XT7A 3JWFA 1DR1A 5E8QA 3FY9X 2ANQA 1DYIA 1JUVA 2FZHA 2INQA 4HA7A 1DG7A 4GH8A 3SGYA 1RX5A 3QL3A 3NZ6X 3D80A 1U71A 3FYVX 2OIPA 3Q1HA 3NZ9X 5HSUA 4M7VA 3SAIA 2AZNA 2CIGA 3F0UX 1LY3A 4XT5A 2CD2A 3NZCX 4X5FA 4KJKA 3SRUX 4QHVA 4NX6A 3DL5A 3I3RA 1RA2A 3L3RA 2BLAA 2L28A 4KL9A 4DDRA 3NXOA 4KY8A 3QLRA 1PDBA 4KNEA 4FGHA 4LAHX 3FYWX 4KY4A 2H2QA 4LAEX 2C2TA 4H96A 1DG5A 3IA4A 3GI2A 3KY8A 1RX8A 1RX7A 1TDRA 2W9SA 4ELGA 3EEKA 3EIGA 3QL0A 5JG0X 3IRMA 3DAUA 3NRRA 1RA9A 4KM0A 3FQOA 3DFRA 4XRBA 4OSGA 1IA1A 3JWCA 2HM9A 4P3RA 3M09A 4QLEA 1DREA 3NZDA 4DPHA 3FRDX 2DHFA 5HVEA 2W3WA 1CD2A 3ROAA 4XT4A 2FZIA 1D1GA 1DRHA 4FGGA 2P4GA 4LAGX 1JOMA 4PTHA 5HPBA 1VJ3A 2W9GA 3SR5X 3SH2A 3GHWA 3FL8A 5HT5A 1RH3A 2W3VA 5DXVA 3FQVA 3RO9A 3ZPGA 1RA3A 3OCHA 3NZBX 4P3QA 4ELHA 1IA2A 3SA2A 1DLSA 4M2XA 1RA8A 3JTWA 3KGYA 3QG2A 4XT6A 3SRQX 1VDRA 3SRRX 2W3BA 2D0KA 3F91A 5HVBA 3OAFA 3FRFX 1DYHA 3JW3A 4QLFA 3QLXA 4XECX 1DHJA
chains in the Genus database with same CATH topology
3JWMA 1DYRA 1S3WA 1HFQA 4PSYA 2BLBA 3GHCA 3NU0A 3IRNA 5U27A 5HI6A 3CD2A 1SEJA 2O7PA 2ZZAA 4H95A 4KEBA 1AOEA 4EJ1A 3K74A 3FY8X 1MVSA 5FDAA 3UM8A 2OBCA 4KJJA 3JSUA 1OHKA 3E0BA 2C2SA 3FRBX 2DRCA 3VCOA 2FZJA 4I1NA 4M7UA 1DDSA 3FREX 1S3YA 3FRAX 5ECCA 3S3VA 4I13A 2D5NA 1RX6A 4HOFA 1ZDRA 3NXYA 3FQCA 1DR5A 1RA1A 3LG4A 3KJRA 3GYFA 1M79A 3FQ0A 4XE6X 3UM5A 5HQZA 4TU5X 4X5HA 3NXVA 1DRFA 2W3MA 5HT4A 3IROA 2BLCA 4Q0DA 1S3UA 1LUDA 4RGCA 5HQYA 1JOLA 3JWKA 3NTZA 1MVTA 3N0HA 4ELBA 1OHJA 1J3IA 4KJLA 3KJSA 3IX9A 4NX7A 3TQAA 2QK8A 4G3MA 2W3AA 3FS6A 3DATA 1BZFA 5HUIA 3CSEA 3JW5A 3I8AX 4EIGA 3NZAX 1J3KA 1U72A 1AO8A 3TQ9A 1IA3A 1RX1A 4H97A 2JYBA 3HJ3A 1RF7A 1DAJA 3DRCA 4LEKX 4PTJA 1DRBA 3DGAA 2LF1A 4FHBA 4ELFA 2B3ZA 4KLXA 1DDRA 1RB3A 4Q6AA 3FQFA 4DPDA 1DR2A 5U26A 4CD2A 3NXXA 3NXRA 1RX2A 1RG7A 3QGTA 3NXTA 1KMVA 4M6JA 1RE7A 5CC9A 1RX9A 3QLWA 2G6VA 4KD7A 5ECXA 3DL6A 1CZ3A 3QFXA 2GD9A 4DFRA 4EILA 4QJZD 4H98A 1RD7A 3QYLA 4X5JA 4ECKA 4DP3A 4EIZA 4ELEA 2W9TA 4P68A 1U70A 1BOZA 1DLRA 3KFYA 4OR7A 1E26A 3S9UA 3FQZA 4XT8A 4KFJA 1M7AA 4G8ZX 4KM2A 1DR7A 1RX4A 3K45A 3ZPCA 3F0QX 3QLZA 1KLKA 2XW7A 3F0XX 4PSSA 5JA3A 1QZFA 4X5GA 4HA9A 3GHVA 3CL9A 1DRAA 1DYJA 4PDJA 1J3JA 3F8ZA 4QI9A 1DR4A 3EX8A 1S3VA 3SA1A 2W9HA 3SQYX 6DFRA 1DIUA 5HF2X 7DFRA 2ANOA 4G95A 3D84X 3HBBA 3K47A 1RC4A 3INVA 4KAKA 3EEJA 4Q0EA 2KGKA 8DFRA 1PD9A 3F0BX 3F0VX 3DG8A 1M78A 2HXVA 4QJCA 1AI9A 1DHFA 1DISA 3S7AA 1DR3A 1DR6A 3RG9A 4KBNA 3EEMA 3QYOA 1IA4A 3F8YA 4IXFX 3TD8A 3K2HA 3SRSX 3SRWX 2BL9A 5CCCA 1PD8A 3EELA 3QLSA 4X5IA 1LY4A 5EAJA 4QLGA 5DFRA 1KMSA 4HOEA 1HFRA 2ITHA 1RB2A 4IXED 3CLBA 5HSRA 4PSTA 3QLYA 3IA5A 4M6KA 1HFPA 3TQ8A 4M6LA 1DG8A 4Q67A 3UM6A 4HOGA 1RX3A 3F0SX 2HQPA 3FL9A 3M08A 4P66A 3TQBA 4IXGX 3R33A 3JVXA 1YHOA 5HF0X 1DF7A 1DHIA 4KYAA 4XT7A 3JWFA 1DR1A 5E8QA 3FY9X 2ANQA 1DYIA 1JUVA 2FZHA 2INQA 4HA7A 1DG7A 4GH8A 3SGYA 1RX5A 3QL3A 3NZ6X 3D80A 1U71A 3FYVX 2OIPA 3Q1HA 3NZ9X 5HSUA 4M7VA 3SAIA 2AZNA 2CIGA 3F0UX 1LY3A 4XT5A 2CD2A 3NZCX 4X5FA 4KJKA 3SRUX 4QHVA 4NX6A 3DL5A 3I3RA 1RA2A 3L3RA 2BLAA 2L28A 4KL9A 4DDRA 3NXOA 4KY8A 3QLRA 1PDBA 4KNEA 4FGHA 4LAHX 3FYWX 4KY4A 2H2QA 4LAEX 2C2TA 4H96A 1DG5A 3IA4A 3GI2A 3KY8A 1RX8A 1RX7A 1TDRA 2W9SA 4ELGA 3EEKA 3EIGA 3QL0A 5JG0X 3IRMA 3DAUA 3NRRA 1RA9A 4KM0A 3FQOA 3DFRA 4XRBA 4OSGA 1IA1A 3JWCA 2HM9A 4P3RA 3M09A 4QLEA 1DREA 3NZDA 4DPHA 3FRDX 2DHFA 5HVEA 2W3WA 1CD2A 3ROAA 4XT4A 2FZIA 1D1GA 1DRHA 4FGGA 2P4GA 4LAGX 1JOMA 4PTHA 5HPBA 1VJ3A 2W9GA 3SR5X 3SH2A 3GHWA 3FL8A 5HT5A 1RH3A 2W3VA 5DXVA 3FQVA 3RO9A 3ZPGA 1RA3A 3OCHA 3NZBX 4P3QA 4ELHA 1IA2A 3SA2A 1DLSA 4M2XA 1RA8A 3JTWA 3KGYA 3QG2A 4XT6A 3SRQX 1VDRA 3SRRX 2W3BA 2D0KA 3F91A 5HVBA 3OAFA 3FRFX 1DYHA 3JW3A 4QLFA 3QLXA 4XECX 1DHJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JWM A;  1DYR A;  1S3W A;  1HFQ A;  4PSY A;  2BLB A;  3GHC A;  3NU0 A;  3IRN A;  5U27 A;  5HI6 A;  3CD2 A;  1SEJ A;  2O7P A;  2ZZA A;  4H95 A;  4KEB A;  1AOE A;  4EJ1 A;  3K74 A;  3FY8 X;  1MVS A;  5FDA A;  3UM8 A;  2OBC A;  4KJJ A;  3JSU A;  1OHK A;  3E0B A;  2C2S A;  3FRB X;  2DRC A;  3VCO A;  2FZJ A;  4I1N A;  4M7U A;  1DDS A;  3FRE X;  1S3Y A;  3FRA X;  5ECC A;  3S3V A;  4I13 A;  2D5N A;  1RX6 A;  4HOF A;  1ZDR A;  3NXY A;  3FQC A;  1DR5 A;  1RA1 A;  3LG4 A;  3KJR A;  3GYF A;  1M79 A;  3FQ0 A;  4XE6 X;  3UM5 A;  5HQZ A;  4TU5 X;  4X5H A;  3NXV A;  1DRF A;  2W3M A;  5HT4 A;  3IRO A;  2BLC A;  4Q0D A;  1S3U A;  1LUD A;  4RGC A;  5HQY A;  1JOL A;  3JWK A;  3NTZ A;  1MVT A;  3N0H A;  4ELB A;  1OHJ A;  1J3I A;  4KJL A;  3KJS A;  3IX9 A;  4NX7 A;  3TQA A;  2QK8 A;  4G3M A;  2W3A A;  3FS6 A;  3DAT A;  1BZF A;  5HUI A;  3CSE A;  3JW5 A;  3I8A X;  4EIG A;  3NZA X;  1J3K A;  1U72 A;  1AO8 A;  3TQ9 A;  1IA3 A;  1RX1 A;  4H97 A;  2JYB A;  3HJ3 A;  1RF7 A;  1DAJ A;  3DRC A;  4LEK X;  4PTJ A;  1DRB A;  3DGA A;  2LF1 A;  4FHB A;  4ELF A;  2B3Z A;  4KLX A;  1DDR A;  1RB3 A;  4Q6A A;  3FQF A;  4DPD A;  1DR2 A;  5U26 A;  4CD2 A;  3NXX A;  3NXR A;  1RX2 A;  1RG7 A;  3QGT A;  3NXT A;  1KMV A;  4M6J A;  1RE7 A;  5CC9 A;  1RX9 A;  3QLW A;  2G6V A;  4KD7 A;  5ECX A;  3DL6 A;  1CZ3 A;  3QFX A;  2GD9 A;  4DFR A;  4EIL A;  4QJZ D;  4H98 A;  1RD7 A;  3QYL A;  4X5J A;  4ECK A;  4DP3 A;  4EIZ A;  4ELE A;  2W9T A;  4P68 A;  1U70 A;  1BOZ A;  1DLR A;  3KFY A;  4OR7 A;  1E26 A;  3S9U A;  3FQZ A;  4XT8 A;  4KFJ A;  1M7A A;  4G8Z X;  4KM2 A;  1DR7 A;  1RX4 A;  3K45 A;  3ZPC A;  3F0Q X;  3QLZ A;  1KLK A;  2XW7 A;  3F0X X;  4PSS A;  5JA3 A;  1QZF A;  4X5G A;  4HA9 A;  3GHV A;  3CL9 A;  1DRA A;  1DYJ A;  4PDJ A;  1J3J A;  3F8Z A;  4QI9 A;  1DR4 A;  3EX8 A;  1S3V A;  3SA1 A;  2W9H A;  3SQY X;  6DFR A;  1DIU A;  5HF2 X;  7DFR A;  2ANO A;  4G95 A;  3D84 X;  3HBB A;  3K47 A;  1RC4 A;  3INV A;  4KAK A;  3EEJ A;  4Q0E A;  2KGK A;  8DFR A;  1PD9 A;  3F0B X;  3F0V X;  3DG8 A;  1M78 A;  2HXV A;  4QJC A;  1AI9 A;  1DHF A;  1DIS A;  3S7A A;  1DR3 A;  1DR6 A;  3RG9 A;  4KBN A;  3EEM A;  3QYO A;  1IA4 A;  3F8Y A;  4IXF X;  3TD8 A;  3K2H A;  3SRS X;  3SRW X;  2BL9 A;  5CCC A;  1PD8 A;  3EEL A;  3QLS A;  4X5I A;  1LY4 A;  5EAJ A;  4QLG A;  5DFR A;  1KMS A;  4HOE A;  1HFR A;  2ITH A;  1RB2 A;  4IXE D;  3CLB A;  5HSR A;  4PST A;  3QLY A;  3IA5 A;  4M6K A;  1HFP A;  3TQ8 A;  4M6L A;  1DG8 A;  4Q67 A;  3UM6 A;  4HOG A;  1RX3 A;  3F0S X;  2HQP A;  3FL9 A;  3M08 A;  4P66 A;  3TQB A;  4IXG X;  3R33 A;  3JVX A;  1YHO A;  5HF0 X;  1DF7 A;  1DHI A;  4KYA A;  4XT7 A;  3JWF A;  1DR1 A;  5E8Q A;  3FY9 X;  2ANQ A;  1DYI A;  1JUV A;  2FZH A;  2INQ A;  4HA7 A;  1DG7 A;  4GH8 A;  3SGY A;  1RX5 A;  3QL3 A;  3NZ6 X;  3D80 A;  1U71 A;  3FYV X;  2OIP A;  3Q1H A;  3NZ9 X;  5HSU A;  4M7V A;  3SAI A;  2AZN A;  2CIG A;  3F0U X;  1LY3 A;  4XT5 A;  2CD2 A;  3NZC X;  4X5F A;  4KJK A;  3SRU X;  4QHV A;  4NX6 A;  3DL5 A;  3I3R A;  1RA2 A;  3L3R A;  2BLA A;  2L28 A;  4KL9 A;  4DDR A;  3NXO A;  4KY8 A;  3QLR A;  1PDB A;  4KNE A;  4FGH A;  4LAH X;  3FYW X;  4KY4 A;  2H2Q A;  4LAE X;  2C2T A;  4H96 A;  1DG5 A;  3IA4 A;  3GI2 A;  3KY8 A;  1RX8 A;  1RX7 A;  1TDR A;  2W9S A;  4ELG A;  3EEK A;  3EIG A;  3QL0 A;  5JG0 X;  3IRM A;  3DAU A;  3NRR A;  1RA9 A;  4KM0 A;  3FQO A;  3DFR A;  4XRB A;  4OSG A;  1IA1 A;  3JWC A;  2HM9 A;  4P3R A;  3M09 A;  4QLE A;  1DRE A;  3NZD A;  4DPH A;  3FRD X;  2DHF A;  5HVE A;  2W3W A;  1CD2 A;  3ROA A;  4XT4 A;  2FZI A;  1D1G A;  1DRH A;  4FGG A;  2P4G A;  4LAG X;  1JOM A;  4PTH A;  5HPB A;  1VJ3 A;  2W9G A;  3SR5 X;  3SH2 A;  3GHW A;  3FL8 A;  5HT5 A;  1RH3 A;  2W3V A;  5DXV A;  3FQV A;  3RO9 A;  3ZPG A;  1RA3 A;  3OCH A;  3NZB X;  4P3Q A;  4ELH A;  1IA2 A;  3SA2 A;  1DLS A;  4M2X A;  1RA8 A;  3JTW A;  3KGY A;  3QG2 A;  4XT6 A;  3SRQ X;  1VDR A;  3SRR X;  2W3B A;  2D0K A;  3F91 A;  5HVB A;  3OAF A;  3FRF X;  1DYH A;  3JW3 A;  4QLF A;  3QLX A;  4XEC X;  1DHJ A; 
#chains in the Genus database with same CATH topology
 3JWM A;  1DYR A;  1S3W A;  1HFQ A;  4PSY A;  2BLB A;  3GHC A;  3NU0 A;  3IRN A;  5U27 A;  5HI6 A;  3CD2 A;  1SEJ A;  2O7P A;  2ZZA A;  4H95 A;  4KEB A;  1AOE A;  4EJ1 A;  3K74 A;  3FY8 X;  1MVS A;  5FDA A;  3UM8 A;  2OBC A;  4KJJ A;  3JSU A;  1OHK A;  3E0B A;  2C2S A;  3FRB X;  2DRC A;  3VCO A;  2FZJ A;  4I1N A;  4M7U A;  1DDS A;  3FRE X;  1S3Y A;  3FRA X;  5ECC A;  3S3V A;  4I13 A;  2D5N A;  1RX6 A;  4HOF A;  1ZDR A;  3NXY A;  3FQC A;  1DR5 A;  1RA1 A;  3LG4 A;  3KJR A;  3GYF A;  1M79 A;  3FQ0 A;  4XE6 X;  3UM5 A;  5HQZ A;  4TU5 X;  4X5H A;  3NXV A;  1DRF A;  2W3M A;  5HT4 A;  3IRO A;  2BLC A;  4Q0D A;  1S3U A;  1LUD A;  4RGC A;  5HQY A;  1JOL A;  3JWK A;  3NTZ A;  1MVT A;  3N0H A;  4ELB A;  1OHJ A;  1J3I A;  4KJL A;  3KJS A;  3IX9 A;  4NX7 A;  3TQA A;  2QK8 A;  4G3M A;  2W3A A;  3FS6 A;  3DAT A;  1BZF A;  5HUI A;  3CSE A;  3JW5 A;  3I8A X;  4EIG A;  3NZA X;  1J3K A;  1U72 A;  1AO8 A;  3TQ9 A;  1IA3 A;  1RX1 A;  4H97 A;  2JYB A;  3HJ3 A;  1RF7 A;  1DAJ A;  3DRC A;  4LEK X;  4PTJ A;  1DRB A;  3DGA A;  2LF1 A;  4FHB A;  4ELF A;  2B3Z A;  4KLX A;  1DDR A;  1RB3 A;  4Q6A A;  3FQF A;  4DPD A;  1DR2 A;  5U26 A;  4CD2 A;  3NXX A;  3NXR A;  1RX2 A;  1RG7 A;  3QGT A;  3NXT A;  1KMV A;  4M6J A;  1RE7 A;  5CC9 A;  1RX9 A;  3QLW A;  2G6V A;  4KD7 A;  5ECX A;  3DL6 A;  1CZ3 A;  3QFX A;  2GD9 A;  4DFR A;  4EIL A;  4QJZ D;  4H98 A;  1RD7 A;  3QYL A;  4X5J A;  4ECK A;  4DP3 A;  4EIZ A;  4ELE A;  2W9T A;  4P68 A;  1U70 A;  1BOZ A;  1DLR A;  3KFY A;  4OR7 A;  1E26 A;  3S9U A;  3FQZ A;  4XT8 A;  4KFJ A;  1M7A A;  4G8Z X;  4KM2 A;  1DR7 A;  1RX4 A;  3K45 A;  3ZPC A;  3F0Q X;  3QLZ A;  1KLK A;  2XW7 A;  3F0X X;  4PSS A;  5JA3 A;  1QZF A;  4X5G A;  4HA9 A;  3GHV A;  3CL9 A;  1DRA A;  1DYJ A;  4PDJ A;  1J3J A;  3F8Z A;  4QI9 A;  1DR4 A;  3EX8 A;  1S3V A;  3SA1 A;  2W9H A;  3SQY X;  6DFR A;  1DIU A;  5HF2 X;  7DFR A;  2ANO A;  4G95 A;  3D84 X;  3HBB A;  3K47 A;  1RC4 A;  3INV A;  4KAK A;  3EEJ A;  4Q0E A;  2KGK A;  8DFR A;  1PD9 A;  3F0B X;  3F0V X;  3DG8 A;  1M78 A;  2HXV A;  4QJC A;  1AI9 A;  1DHF A;  1DIS A;  3S7A A;  1DR3 A;  1DR6 A;  3RG9 A;  4KBN A;  3EEM A;  3QYO A;  1IA4 A;  3F8Y A;  4IXF X;  3TD8 A;  3K2H A;  3SRS X;  3SRW X;  2BL9 A;  5CCC A;  1PD8 A;  3EEL A;  3QLS A;  4X5I A;  1LY4 A;  5EAJ A;  4QLG A;  5DFR A;  1KMS A;  4HOE A;  1HFR A;  2ITH A;  1RB2 A;  4IXE D;  3CLB A;  5HSR A;  4PST A;  3QLY A;  3IA5 A;  4M6K A;  1HFP A;  3TQ8 A;  4M6L A;  1DG8 A;  4Q67 A;  3UM6 A;  4HOG A;  1RX3 A;  3F0S X;  2HQP A;  3FL9 A;  3M08 A;  4P66 A;  3TQB A;  4IXG X;  3R33 A;  3JVX A;  1YHO A;  5HF0 X;  1DF7 A;  1DHI A;  4KYA A;  4XT7 A;  3JWF A;  1DR1 A;  5E8Q A;  3FY9 X;  2ANQ A;  1DYI A;  1JUV A;  2FZH A;  2INQ A;  4HA7 A;  1DG7 A;  4GH8 A;  3SGY A;  1RX5 A;  3QL3 A;  3NZ6 X;  3D80 A;  1U71 A;  3FYV X;  2OIP A;  3Q1H A;  3NZ9 X;  5HSU A;  4M7V A;  3SAI A;  2AZN A;  2CIG A;  3F0U X;  1LY3 A;  4XT5 A;  2CD2 A;  3NZC X;  4X5F A;  4KJK A;  3SRU X;  4QHV A;  4NX6 A;  3DL5 A;  3I3R A;  1RA2 A;  3L3R A;  2BLA A;  2L28 A;  4KL9 A;  4DDR A;  3NXO A;  4KY8 A;  3QLR A;  1PDB A;  4KNE A;  4FGH A;  4LAH X;  3FYW X;  4KY4 A;  2H2Q A;  4LAE X;  2C2T A;  4H96 A;  1DG5 A;  3IA4 A;  3GI2 A;  3KY8 A;  1RX8 A;  1RX7 A;  1TDR A;  2W9S A;  4ELG A;  3EEK A;  3EIG A;  3QL0 A;  5JG0 X;  3IRM A;  3DAU A;  3NRR A;  1RA9 A;  4KM0 A;  3FQO A;  3DFR A;  4XRB A;  4OSG A;  1IA1 A;  3JWC A;  2HM9 A;  4P3R A;  3M09 A;  4QLE A;  1DRE A;  3NZD A;  4DPH A;  3FRD X;  2DHF A;  5HVE A;  2W3W A;  1CD2 A;  3ROA A;  4XT4 A;  2FZI A;  1D1G A;  1DRH A;  4FGG A;  2P4G A;  4LAG X;  1JOM A;  4PTH A;  5HPB A;  1VJ3 A;  2W9G A;  3SR5 X;  3SH2 A;  3GHW A;  3FL8 A;  5HT5 A;  1RH3 A;  2W3V A;  5DXV A;  3FQV A;  3RO9 A;  3ZPG A;  1RA3 A;  3OCH A;  3NZB X;  4P3Q A;  4ELH A;  1IA2 A;  3SA2 A;  1DLS A;  4M2X A;  1RA8 A;  3JTW A;  3KGY A;  3QG2 A;  4XT6 A;  3SRQ X;  1VDR A;  3SRR X;  2W3B A;  2D0K A;  3F91 A;  5HVB A;  3OAF A;  3FRF X;  1DYH A;  3JW3 A;  4QLF A;  3QLX A;  4XEC X;  1DHJ A; 
#chains in the Genus database with same CATH homology
 3JWM A;  1DYR A;  1S3W A;  1HFQ A;  4PSY A;  2BLB A;  3GHC A;  3NU0 A;  3IRN A;  5U27 A;  5HI6 A;  3CD2 A;  1SEJ A;  2O7P A;  2ZZA A;  4H95 A;  4KEB A;  1AOE A;  4EJ1 A;  3K74 A;  3FY8 X;  1MVS A;  5FDA A;  3UM8 A;  2OBC A;  4KJJ A;  3JSU A;  1OHK A;  3E0B A;  2C2S A;  3FRB X;  2DRC A;  3VCO A;  2FZJ A;  4I1N A;  4M7U A;  1DDS A;  3FRE X;  1S3Y A;  3FRA X;  5ECC A;  3S3V A;  4I13 A;  2D5N A;  1RX6 A;  4HOF A;  1ZDR A;  3NXY A;  3FQC A;  1DR5 A;  1RA1 A;  3LG4 A;  3KJR A;  3GYF A;  1M79 A;  3FQ0 A;  4XE6 X;  3UM5 A;  5HQZ A;  4TU5 X;  4X5H A;  3NXV A;  1DRF A;  2W3M A;  5HT4 A;  3IRO A;  2BLC A;  4Q0D A;  1S3U A;  1LUD A;  4RGC A;  5HQY A;  1JOL A;  3JWK A;  3NTZ A;  1MVT A;  3N0H A;  4ELB A;  1OHJ A;  1J3I A;  4KJL A;  3KJS A;  3IX9 A;  4NX7 A;  3TQA A;  2QK8 A;  4G3M A;  2W3A A;  3FS6 A;  3DAT A;  1BZF A;  5HUI A;  3CSE A;  3JW5 A;  3I8A X;  4EIG A;  3NZA X;  1J3K A;  1U72 A;  1AO8 A;  3TQ9 A;  1IA3 A;  1RX1 A;  4H97 A;  2JYB A;  3HJ3 A;  1RF7 A;  1DAJ A;  3DRC A;  4LEK X;  4PTJ A;  1DRB A;  3DGA A;  2LF1 A;  4FHB A;  4ELF A;  2B3Z A;  4KLX A;  1DDR A;  1RB3 A;  4Q6A A;  3FQF A;  4DPD A;  1DR2 A;  5U26 A;  4CD2 A;  3NXX A;  3NXR A;  1RX2 A;  1RG7 A;  3QGT A;  3NXT A;  1KMV A;  4M6J A;  1RE7 A;  5CC9 A;  1RX9 A;  3QLW A;  2G6V A;  4KD7 A;  5ECX A;  3DL6 A;  1CZ3 A;  3QFX A;  2GD9 A;  4DFR A;  4EIL A;  4QJZ D;  4H98 A;  1RD7 A;  3QYL A;  4X5J A;  4ECK A;  4DP3 A;  4EIZ A;  4ELE A;  2W9T A;  4P68 A;  1U70 A;  1BOZ A;  1DLR A;  3KFY A;  4OR7 A;  1E26 A;  3S9U A;  3FQZ A;  4XT8 A;  4KFJ A;  1M7A A;  4G8Z X;  4KM2 A;  1DR7 A;  1RX4 A;  3K45 A;  3ZPC A;  3F0Q X;  3QLZ A;  1KLK A;  2XW7 A;  3F0X X;  4PSS A;  5JA3 A;  1QZF A;  4X5G A;  4HA9 A;  3GHV A;  3CL9 A;  1DRA A;  1DYJ A;  4PDJ A;  1J3J A;  3F8Z A;  4QI9 A;  1DR4 A;  3EX8 A;  1S3V A;  3SA1 A;  2W9H A;  3SQY X;  6DFR A;  1DIU A;  5HF2 X;  7DFR A;  2ANO A;  4G95 A;  3D84 X;  3HBB A;  3K47 A;  1RC4 A;  3INV A;  4KAK A;  3EEJ A;  4Q0E A;  2KGK A;  8DFR A;  1PD9 A;  3F0B X;  3F0V X;  3DG8 A;  1M78 A;  2HXV A;  4QJC A;  1AI9 A;  1DHF A;  1DIS A;  3S7A A;  1DR3 A;  1DR6 A;  3RG9 A;  4KBN A;  3EEM A;  3QYO A;  1IA4 A;  3F8Y A;  4IXF X;  3TD8 A;  3K2H A;  3SRS X;  3SRW X;  2BL9 A;  5CCC A;  1PD8 A;  3EEL A;  3QLS A;  4X5I A;  1LY4 A;  5EAJ A;  4QLG A;  5DFR A;  1KMS A;  4HOE A;  1HFR A;  2ITH A;  1RB2 A;  4IXE D;  3CLB A;  5HSR A;  4PST A;  3QLY A;  3IA5 A;  4M6K A;  1HFP A;  3TQ8 A;  4M6L A;  1DG8 A;  4Q67 A;  3UM6 A;  4HOG A;  1RX3 A;  3F0S X;  2HQP A;  3FL9 A;  3M08 A;  4P66 A;  3TQB A;  4IXG X;  3R33 A;  3JVX A;  1YHO A;  5HF0 X;  1DF7 A;  1DHI A;  4KYA A;  4XT7 A;  3JWF A;  1DR1 A;  5E8Q A;  3FY9 X;  2ANQ A;  1DYI A;  1JUV A;  2FZH A;  2INQ A;  4HA7 A;  1DG7 A;  4GH8 A;  3SGY A;  1RX5 A;  3QL3 A;  3NZ6 X;  3D80 A;  1U71 A;  3FYV X;  2OIP A;  3Q1H A;  3NZ9 X;  5HSU A;  4M7V A;  3SAI A;  2AZN A;  2CIG A;  3F0U X;  1LY3 A;  4XT5 A;  2CD2 A;  3NZC X;  4X5F A;  4KJK A;  3SRU X;  4QHV A;  4NX6 A;  3DL5 A;  3I3R A;  1RA2 A;  3L3R A;  2BLA A;  2L28 A;  4KL9 A;  4DDR A;  3NXO A;  4KY8 A;  3QLR A;  1PDB A;  4KNE A;  4FGH A;  4LAH X;  3FYW X;  4KY4 A;  2H2Q A;  4LAE X;  2C2T A;  4H96 A;  1DG5 A;  3IA4 A;  3GI2 A;  3KY8 A;  1RX8 A;  1RX7 A;  1TDR A;  2W9S A;  4ELG A;  3EEK A;  3EIG A;  3QL0 A;  5JG0 X;  3IRM A;  3DAU A;  3NRR A;  1RA9 A;  4KM0 A;  3FQO A;  3DFR A;  4XRB A;  4OSG A;  1IA1 A;  3JWC A;  2HM9 A;  4P3R A;  3M09 A;  4QLE A;  1DRE A;  3NZD A;  4DPH A;  3FRD X;  2DHF A;  5HVE A;  2W3W A;  1CD2 A;  3ROA A;  4XT4 A;  2FZI A;  1D1G A;  1DRH A;  4FGG A;  2P4G A;  4LAG X;  1JOM A;  4PTH A;  5HPB A;  1VJ3 A;  2W9G A;  3SR5 X;  3SH2 A;  3GHW A;  3FL8 A;  5HT5 A;  1RH3 A;  2W3V A;  5DXV A;  3FQV A;  3RO9 A;  3ZPG A;  1RA3 A;  3OCH A;  3NZB X;  4P3Q A;  4ELH A;  1IA2 A;  3SA2 A;  1DLS A;  4M2X A;  1RA8 A;  3JTW A;  3KGY A;  3QG2 A;  4XT6 A;  3SRQ X;  1VDR A;  3SRR X;  2W3B A;  2D0K A;  3F91 A;  5HVB A;  3OAF A;  3FRF X;  1DYH A;  3JW3 A;  4QLF A;  3QLX A;  4XEC X;  1DHJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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