3SRRX

S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines.
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Staphylococcus aureus
molecule keywords Dihydrofolate reductase
total genus 40
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2011-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 3srrX00
4NX7A 3R33A 3QFXA 3S7AA 4EIZA 2W3MA 4ELGA 1DYJA 4Q6AA 6DFRA 3DATA 1RF7A 4QLFA 5DXVA 3GI2A 4LEKX 5ECXA 3KJSA 1DIUA 1DG7A 1DHJA 3DRCA 3SRSX 5HPBA 5HT5A 4OSGA 4KY4A 3DL6A 2O7PA 3CD2A 4DFRA 3EX8A 1DREA 3NXOA 3EELA 4H97A 3S3VA 3KJRA 3RO9A 1AOEA 4XT8A 3TD8A 1PDBA 2XW7A 5HF2X 4QJZD 1MVTA 3F0BX 3K2HA 3QG2A 3SA1A 3FQ0A 3K74A 5CCCA 3SA2A 3VCOA 1M7AA 1DDSA 3DGAA 4LAEX 4X5GA 2JYBA 3D80A 1J3KA 1RX4A 4P66A 3IA5A 4KBNA 5HVBA 5HUIA 3DFRA 1LY3A 3NZ9X 3E0BA 1RG7A 4PSSA 3JVXA 1DR3A 1OHKA 1RA9A 1DR2A 1RX6A 2W9GA 1DYRA 3DAUA 2OIPA 4DPHA 1DR7A 2BLAA 2FZJA 3QLXA 5HF0X 1HFPA 2ANQA 2OBCA 3NXTA 3FQCA 2HQPA 5U27A 1M79A 2W3WA 1HFQA 5ECCA 2CD2A 3FY9X 5HQZA 3K45A 3JTWA 4IXGX 4FHBA 3UM5A 3F0SX 3QL0A 3KGYA 3Q1HA 5HT4A 3SRWX 3QLRA 3DG8A 3JWFA 3ZPGA 3NXVA 1YHOA 3L3RA 1DDRA 4KY8A 1ZDRA 4G8ZX 2W9SA 1RX7A 3F8ZA 4G95A 4P68A 1VDRA 4Q0EA 4XE6X 3JWMA 3NZ6X 2INQA 1MVSA 4EJ1A 3QYOA 3F0XX 3IX9A 4PSYA 5E8QA 3SAIA 3F91A 3GYFA 2HM9A 1DRFA 1BZFA 2HXVA 1AI9A 3FQOA 4ELHA 2W3BA 4M7VA 3M08A 4DPDA 3EEKA 3FQFA 4PDJA 1OHJA 1VJ3A 3FQVA 5DFRA 4KYAA 3F0QX 1DLRA 4PSTA 3FL8A 2C2SA 1DYIA 4I13A 3QLZA 3EIGA 1TDRA 3EEMA 4TU5X 4XT7A 1DR5A 4ELFA 2H2QA 3EEJA 3INVA 2W3AA 3NZCX 4M6JA 3M09A 1DG5A 2BLBA 1M78A 5HVEA 3GHVA 4KJKA 2D5NA 3JW5A 1DR1A 1S3WA 3QLYA 4H98A 1RD7A 3TQ9A 3NXYA 1DISA 3FRFX 1DR4A 1E26A 3JSUA 3GHWA 3QLSA 4FGHA 4CD2A 3F8YA 2KGKA 3NZBX 3SRRX 1IA4A 3JWKA 2BL9A 4KLXA 1RX2A 2ANOA 1S3YA 1CD2A 1LUDA 4HOFA 1RX1A 1PD9A 1J3JA 3DL5A 3TQBA 3GHCA 3ZPCA 3OCHA 3FRAX 4HOGA 5CC9A 3IRNA 4QHVA 1RC4A 1KMVA 3IRMA 3N0HA 1RE7A 3FRDX 3HBBA 4KM0A 3SH2A 4HA9A 4QLGA 4H96A 2FZIA 3SRQX 3NZDA 1JOLA 2DHFA 4KNEA 3CLBA 5JG0X 3SQYX 1RH3A 4KJLA 4KJJA 3F0UX 4Q0DA 3SRUX 5HSRA 1KMSA 4HA7A 4M6LA 4PTJA 1KLKA 2ITHA 1U70A 1HFRA 4RGCA 2W9HA 3CSEA 1DYHA 3FYWX 3LG4A 2B3ZA 1LY4A 4EIGA 3QL3A 2DRCA 3I8AX 1DR6A 2L28A 3NZAX 1DLSA 2FZHA 1PD8A 3FRBX 3SGYA 1BOZA 2QK8A 3FYVX 1DRBA 4M7UA 3K47A 4M6KA 3QGTA 1D1GA 5EAJA 1SEJA 3F0VX 2CIGA 4FGGA 4M2XA 1RA1A 1IA1A 4XT5A 3OAFA 4G3MA 4KL9A 4QLEA 2P4GA 3RG9A 1DG8A 1DRAA 4KFJA 4QI9A 1RA3A 2C2TA 4IXFX 1RX5A 1U71A 3IA4A 2GD9A 3D84X 4P3QA 4GH8A 2D0KA 4P3RA 3I3RA 4X5FA 5HSUA 8DFRA 1DF7A 4NX6A 2LF1A 3UM6A 1QZFA 1IA2A 3HJ3A 1RX3A 3ROAA 3FS6A 5U26A 4ELEA 4DP3A 5FDAA 3KY8A 4Q67A 3S9UA 1RB2A 3NRRA 5HI6A 3NU0A 4KD7A 4X5JA 1RX8A 3JWCA 3NTZA 4LAHX 4KEBA 2G6VA 4ELBA 3JW3A 3NXRA 4HOEA 4H95A 4XT4A 1S3VA 1J3IA 1JUVA 4OR7A 3IROA 3CL9A 1RX9A 4IXED 3FQZA 3QLWA 1DAJA 4ECKA 1RA8A 4PTHA 1DRHA 4EILA 3FY8X 3TQ8A 4X5IA 5JA3A 1JOMA 1DHIA 3FL9A 3NXXA 4KM2A 2W9TA 3QYLA 4QJCA 3TQAA 3UM8A 2ZZAA 1IA3A 4KAKA 1AO8A 4XT6A 4LAGX 3FREX 1DHFA 1RB3A 4X5HA 4XRBA 3SR5X 3KFYA 4XECX 4I1NA 1RA2A 2AZNA 7DFRA 1CZ3A 2W3VA 1S3UA 1U72A 5HQYA 2BLCA 4DDRA
chains in the Genus database with same CATH superfamily
4NX7A 3R33A 3QFXA 3S7AA 4EIZA 2W3MA 4ELGA 1DYJA 4Q6AA 6DFRA 3DATA 1RF7A 4QLFA 5DXVA 3GI2A 4LEKX 5ECXA 3KJSA 1DIUA 1DG7A 1DHJA 3DRCA 3SRSX 5HPBA 5HT5A 4OSGA 4KY4A 3DL6A 2O7PA 3CD2A 4DFRA 3EX8A 1DREA 3NXOA 3EELA 4H97A 3S3VA 3KJRA 3RO9A 1AOEA 4XT8A 3TD8A 1PDBA 2XW7A 5HF2X 4QJZD 1MVTA 3F0BX 3K2HA 3QG2A 3SA1A 3FQ0A 3K74A 5CCCA 3SA2A 3VCOA 1M7AA 1DDSA 3DGAA 4LAEX 4X5GA 2JYBA 3D80A 1J3KA 1RX4A 4P66A 3IA5A 4KBNA 5HVBA 5HUIA 3DFRA 1LY3A 3NZ9X 3E0BA 1RG7A 4PSSA 3JVXA 1DR3A 1OHKA 1RA9A 1DR2A 1RX6A 2W9GA 1DYRA 3DAUA 2OIPA 4DPHA 1DR7A 2BLAA 2FZJA 3QLXA 5HF0X 1HFPA 2ANQA 2OBCA 3NXTA 3FQCA 2HQPA 5U27A 1M79A 2W3WA 1HFQA 5ECCA 2CD2A 3FY9X 5HQZA 3K45A 3JTWA 4IXGX 4FHBA 3UM5A 3F0SX 3QL0A 3KGYA 3Q1HA 5HT4A 3SRWX 3QLRA 3DG8A 3JWFA 3ZPGA 3NXVA 1YHOA 3L3RA 1DDRA 4KY8A 1ZDRA 4G8ZX 2W9SA 1RX7A 3F8ZA 4G95A 4P68A 1VDRA 4Q0EA 4XE6X 3JWMA 3NZ6X 2INQA 1MVSA 4EJ1A 3QYOA 3F0XX 3IX9A 4PSYA 5E8QA 3SAIA 3F91A 3GYFA 2HM9A 1DRFA 1BZFA 2HXVA 1AI9A 3FQOA 4ELHA 2W3BA 4M7VA 3M08A 4DPDA 3EEKA 3FQFA 4PDJA 1OHJA 1VJ3A 3FQVA 5DFRA 4KYAA 3F0QX 1DLRA 4PSTA 3FL8A 2C2SA 1DYIA 4I13A 3QLZA 3EIGA 1TDRA 3EEMA 4TU5X 4XT7A 1DR5A 4ELFA 2H2QA 3EEJA 3INVA 2W3AA 3NZCX 4M6JA 3M09A 1DG5A 2BLBA 1M78A 5HVEA 3GHVA 4KJKA 2D5NA 3JW5A 1DR1A 1S3WA 3QLYA 4H98A 1RD7A 3TQ9A 3NXYA 1DISA 3FRFX 1DR4A 1E26A 3JSUA 3GHWA 3QLSA 4FGHA 4CD2A 3F8YA 2KGKA 3NZBX 3SRRX 1IA4A 3JWKA 2BL9A 4KLXA 1RX2A 2ANOA 1S3YA 1CD2A 1LUDA 4HOFA 1RX1A 1PD9A 1J3JA 3DL5A 3TQBA 3GHCA 3ZPCA 3OCHA 3FRAX 4HOGA 5CC9A 3IRNA 4QHVA 1RC4A 1KMVA 3IRMA 3N0HA 1RE7A 3FRDX 3HBBA 4KM0A 3SH2A 4HA9A 4QLGA 4H96A 2FZIA 3SRQX 3NZDA 1JOLA 2DHFA 4KNEA 3CLBA 5JG0X 3SQYX 1RH3A 4KJLA 4KJJA 3F0UX 4Q0DA 3SRUX 5HSRA 1KMSA 4HA7A 4M6LA 4PTJA 1KLKA 2ITHA 1U70A 1HFRA 4RGCA 2W9HA 3CSEA 1DYHA 3FYWX 3LG4A 2B3ZA 1LY4A 4EIGA 3QL3A 2DRCA 3I8AX 1DR6A 2L28A 3NZAX 1DLSA 2FZHA 1PD8A 3FRBX 3SGYA 1BOZA 2QK8A 3FYVX 1DRBA 4M7UA 3K47A 4M6KA 3QGTA 1D1GA 5EAJA 1SEJA 3F0VX 2CIGA 4FGGA 4M2XA 1RA1A 1IA1A 4XT5A 3OAFA 4G3MA 4KL9A 4QLEA 2P4GA 3RG9A 1DG8A 1DRAA 4KFJA 4QI9A 1RA3A 2C2TA 4IXFX 1RX5A 1U71A 3IA4A 2GD9A 3D84X 4P3QA 4GH8A 2D0KA 4P3RA 3I3RA 4X5FA 5HSUA 8DFRA 1DF7A 4NX6A 2LF1A 3UM6A 1QZFA 1IA2A 3HJ3A 1RX3A 3ROAA 3FS6A 5U26A 4ELEA 4DP3A 5FDAA 3KY8A 4Q67A 3S9UA 1RB2A 3NRRA 5HI6A 3NU0A 4KD7A 4X5JA 1RX8A 3JWCA 3NTZA 4LAHX 4KEBA 2G6VA 4ELBA 3JW3A 3NXRA 4HOEA 4H95A 4XT4A 1S3VA 1J3IA 1JUVA 4OR7A 3IROA 3CL9A 1RX9A 4IXED 3FQZA 3QLWA 1DAJA 4ECKA 1RA8A 4PTHA 1DRHA 4EILA 3FY8X 3TQ8A 4X5IA 5JA3A 1JOMA 1DHIA 3FL9A 3NXXA 4KM2A 2W9TA 3QYLA 4QJCA 3TQAA 3UM8A 2ZZAA 1IA3A 4KAKA 1AO8A 4XT6A 4LAGX 3FREX 1DHFA 1RB3A 4X5HA 4XRBA 3SR5X 3KFYA 4XECX 4I1NA 1RA2A 2AZNA 7DFRA 1CZ3A 2W3VA 1S3UA 1U72A 5HQYA 2BLCA 4DDRA
chains in the Genus database with same CATH topology
4NX7A 3R33A 3QFXA 3S7AA 4EIZA 2W3MA 4ELGA 1DYJA 4Q6AA 6DFRA 3DATA 1RF7A 4QLFA 5DXVA 3GI2A 4LEKX 5ECXA 3KJSA 1DIUA 1DG7A 1DHJA 3DRCA 3SRSX 5HPBA 5HT5A 4OSGA 4KY4A 3DL6A 2O7PA 3CD2A 4DFRA 3EX8A 1DREA 3NXOA 3EELA 4H97A 3S3VA 3KJRA 3RO9A 1AOEA 4XT8A 3TD8A 1PDBA 2XW7A 5HF2X 4QJZD 1MVTA 3F0BX 3K2HA 3QG2A 3SA1A 3FQ0A 3K74A 5CCCA 3SA2A 3VCOA 1M7AA 1DDSA 3DGAA 4LAEX 4X5GA 2JYBA 3D80A 1J3KA 1RX4A 4P66A 3IA5A 4KBNA 5HVBA 5HUIA 3DFRA 1LY3A 3NZ9X 3E0BA 1RG7A 4PSSA 3JVXA 1DR3A 1OHKA 1RA9A 1DR2A 1RX6A 2W9GA 1DYRA 3DAUA 2OIPA 4DPHA 1DR7A 2BLAA 2FZJA 3QLXA 5HF0X 1HFPA 2ANQA 2OBCA 3NXTA 3FQCA 2HQPA 5U27A 1M79A 2W3WA 1HFQA 5ECCA 2CD2A 3FY9X 5HQZA 3K45A 3JTWA 4IXGX 4FHBA 3UM5A 3F0SX 3QL0A 3KGYA 3Q1HA 5HT4A 3SRWX 3QLRA 3DG8A 3JWFA 3ZPGA 3NXVA 1YHOA 3L3RA 1DDRA 4KY8A 1ZDRA 4G8ZX 2W9SA 1RX7A 3F8ZA 4G95A 4P68A 1VDRA 4Q0EA 4XE6X 3JWMA 3NZ6X 2INQA 1MVSA 4EJ1A 3QYOA 3F0XX 3IX9A 4PSYA 5E8QA 3SAIA 3F91A 3GYFA 2HM9A 1DRFA 1BZFA 2HXVA 1AI9A 3FQOA 4ELHA 2W3BA 4M7VA 3M08A 4DPDA 3EEKA 3FQFA 4PDJA 1OHJA 1VJ3A 3FQVA 5DFRA 4KYAA 3F0QX 1DLRA 4PSTA 3FL8A 2C2SA 1DYIA 4I13A 3QLZA 3EIGA 1TDRA 3EEMA 4TU5X 4XT7A 1DR5A 4ELFA 2H2QA 3EEJA 3INVA 2W3AA 3NZCX 4M6JA 3M09A 1DG5A 2BLBA 1M78A 5HVEA 3GHVA 4KJKA 2D5NA 3JW5A 1DR1A 1S3WA 3QLYA 4H98A 1RD7A 3TQ9A 3NXYA 1DISA 3FRFX 1DR4A 1E26A 3JSUA 3GHWA 3QLSA 4FGHA 4CD2A 3F8YA 2KGKA 3NZBX 3SRRX 1IA4A 3JWKA 2BL9A 4KLXA 1RX2A 2ANOA 1S3YA 1CD2A 1LUDA 4HOFA 1RX1A 1PD9A 1J3JA 3DL5A 3TQBA 3GHCA 3ZPCA 3OCHA 3FRAX 4HOGA 5CC9A 3IRNA 4QHVA 1RC4A 1KMVA 3IRMA 3N0HA 1RE7A 3FRDX 3HBBA 4KM0A 3SH2A 4HA9A 4QLGA 4H96A 2FZIA 3SRQX 3NZDA 1JOLA 2DHFA 4KNEA 3CLBA 5JG0X 3SQYX 1RH3A 4KJLA 4KJJA 3F0UX 4Q0DA 3SRUX 5HSRA 1KMSA 4HA7A 4M6LA 4PTJA 1KLKA 2ITHA 1U70A 1HFRA 4RGCA 2W9HA 3CSEA 1DYHA 3FYWX 3LG4A 2B3ZA 1LY4A 4EIGA 3QL3A 2DRCA 3I8AX 1DR6A 2L28A 3NZAX 1DLSA 2FZHA 1PD8A 3FRBX 3SGYA 1BOZA 2QK8A 3FYVX 1DRBA 4M7UA 3K47A 4M6KA 3QGTA 1D1GA 5EAJA 1SEJA 3F0VX 2CIGA 4FGGA 4M2XA 1RA1A 1IA1A 4XT5A 3OAFA 4G3MA 4KL9A 4QLEA 2P4GA 3RG9A 1DG8A 1DRAA 4KFJA 4QI9A 1RA3A 2C2TA 4IXFX 1RX5A 1U71A 3IA4A 2GD9A 3D84X 4P3QA 4GH8A 2D0KA 4P3RA 3I3RA 4X5FA 5HSUA 8DFRA 1DF7A 4NX6A 2LF1A 3UM6A 1QZFA 1IA2A 3HJ3A 1RX3A 3ROAA 3FS6A 5U26A 4ELEA 4DP3A 5FDAA 3KY8A 4Q67A 3S9UA 1RB2A 3NRRA 5HI6A 3NU0A 4KD7A 4X5JA 1RX8A 3JWCA 3NTZA 4LAHX 4KEBA 2G6VA 4ELBA 3JW3A 3NXRA 4HOEA 4H95A 4XT4A 1S3VA 1J3IA 1JUVA 4OR7A 3IROA 3CL9A 1RX9A 4IXED 3FQZA 3QLWA 1DAJA 4ECKA 1RA8A 4PTHA 1DRHA 4EILA 3FY8X 3TQ8A 4X5IA 5JA3A 1JOMA 1DHIA 3FL9A 3NXXA 4KM2A 2W9TA 3QYLA 4QJCA 3TQAA 3UM8A 2ZZAA 1IA3A 4KAKA 1AO8A 4XT6A 4LAGX 3FREX 1DHFA 1RB3A 4X5HA 4XRBA 3SR5X 3KFYA 4XECX 4I1NA 1RA2A 2AZNA 7DFRA 1CZ3A 2W3VA 1S3UA 1U72A 5HQYA 2BLCA 4DDRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NX7 A;  3R33 A;  3QFX A;  3S7A A;  4EIZ A;  2W3M A;  4ELG A;  1DYJ A;  4Q6A A;  6DFR A;  3DAT A;  1RF7 A;  4QLF A;  5DXV A;  3GI2 A;  4LEK X;  5ECX A;  3KJS A;  1DIU A;  1DG7 A;  1DHJ A;  3DRC A;  3SRS X;  5HPB A;  5HT5 A;  4OSG A;  4KY4 A;  3DL6 A;  2O7P A;  3CD2 A;  4DFR A;  3EX8 A;  1DRE A;  3NXO A;  3EEL A;  4H97 A;  3S3V A;  3KJR A;  3RO9 A;  1AOE A;  4XT8 A;  3TD8 A;  1PDB A;  2XW7 A;  5HF2 X;  4QJZ D;  1MVT A;  3F0B X;  3K2H A;  3QG2 A;  3SA1 A;  3FQ0 A;  3K74 A;  5CCC A;  3SA2 A;  3VCO A;  1M7A A;  1DDS A;  3DGA A;  4LAE X;  4X5G A;  2JYB A;  3D80 A;  1J3K A;  1RX4 A;  4P66 A;  3IA5 A;  4KBN A;  5HVB A;  5HUI A;  3DFR A;  1LY3 A;  3NZ9 X;  3E0B A;  1RG7 A;  4PSS A;  3JVX A;  1DR3 A;  1OHK A;  1RA9 A;  1DR2 A;  1RX6 A;  2W9G A;  1DYR A;  3DAU A;  2OIP A;  4DPH A;  1DR7 A;  2BLA A;  2FZJ A;  3QLX A;  5HF0 X;  1HFP A;  2ANQ A;  2OBC A;  3NXT A;  3FQC A;  2HQP A;  5U27 A;  1M79 A;  2W3W A;  1HFQ A;  5ECC A;  2CD2 A;  3FY9 X;  5HQZ A;  3K45 A;  3JTW A;  4IXG X;  4FHB A;  3UM5 A;  3F0S X;  3QL0 A;  3KGY A;  3Q1H A;  5HT4 A;  3SRW X;  3QLR A;  3DG8 A;  3JWF A;  3ZPG A;  3NXV A;  1YHO A;  3L3R A;  1DDR A;  4KY8 A;  1ZDR A;  4G8Z X;  2W9S A;  1RX7 A;  3F8Z A;  4G95 A;  4P68 A;  1VDR A;  4Q0E A;  4XE6 X;  3JWM A;  3NZ6 X;  2INQ A;  1MVS A;  4EJ1 A;  3QYO A;  3F0X X;  3IX9 A;  4PSY A;  5E8Q A;  3SAI A;  3F91 A;  3GYF A;  2HM9 A;  1DRF A;  1BZF A;  2HXV A;  1AI9 A;  3FQO A;  4ELH A;  2W3B A;  4M7V A;  3M08 A;  4DPD A;  3EEK A;  3FQF A;  4PDJ A;  1OHJ A;  1VJ3 A;  3FQV A;  5DFR A;  4KYA A;  3F0Q X;  1DLR A;  4PST A;  3FL8 A;  2C2S A;  1DYI A;  4I13 A;  3QLZ A;  3EIG A;  1TDR A;  3EEM A;  4TU5 X;  4XT7 A;  1DR5 A;  4ELF A;  2H2Q A;  3EEJ A;  3INV A;  2W3A A;  3NZC X;  4M6J A;  3M09 A;  1DG5 A;  2BLB A;  1M78 A;  5HVE A;  3GHV A;  4KJK A;  2D5N A;  3JW5 A;  1DR1 A;  1S3W A;  3QLY A;  4H98 A;  1RD7 A;  3TQ9 A;  3NXY A;  1DIS A;  3FRF X;  1DR4 A;  1E26 A;  3JSU A;  3GHW A;  3QLS A;  4FGH A;  4CD2 A;  3F8Y A;  2KGK A;  3NZB X;  3SRR X;  1IA4 A;  3JWK A;  2BL9 A;  4KLX A;  1RX2 A;  2ANO A;  1S3Y A;  1CD2 A;  1LUD A;  4HOF A;  1RX1 A;  1PD9 A;  1J3J A;  3DL5 A;  3TQB A;  3GHC A;  3ZPC A;  3OCH A;  3FRA X;  4HOG A;  5CC9 A;  3IRN A;  4QHV A;  1RC4 A;  1KMV A;  3IRM A;  3N0H A;  1RE7 A;  3FRD X;  3HBB A;  4KM0 A;  3SH2 A;  4HA9 A;  4QLG A;  4H96 A;  2FZI A;  3SRQ X;  3NZD A;  1JOL A;  2DHF A;  4KNE A;  3CLB A;  5JG0 X;  3SQY X;  1RH3 A;  4KJL A;  4KJJ A;  3F0U X;  4Q0D A;  3SRU X;  5HSR A;  1KMS A;  4HA7 A;  4M6L A;  4PTJ A;  1KLK A;  2ITH A;  1U70 A;  1HFR A;  4RGC A;  2W9H A;  3CSE A;  1DYH A;  3FYW X;  3LG4 A;  2B3Z A;  1LY4 A;  4EIG A;  3QL3 A;  2DRC A;  3I8A X;  1DR6 A;  2L28 A;  3NZA X;  1DLS A;  2FZH A;  1PD8 A;  3FRB X;  3SGY A;  1BOZ A;  2QK8 A;  3FYV X;  1DRB A;  4M7U A;  3K47 A;  4M6K A;  3QGT A;  1D1G A;  5EAJ A;  1SEJ A;  3F0V X;  2CIG A;  4FGG A;  4M2X A;  1RA1 A;  1IA1 A;  4XT5 A;  3OAF A;  4G3M A;  4KL9 A;  4QLE A;  2P4G A;  3RG9 A;  1DG8 A;  1DRA A;  4KFJ A;  4QI9 A;  1RA3 A;  2C2T A;  4IXF X;  1RX5 A;  1U71 A;  3IA4 A;  2GD9 A;  3D84 X;  4P3Q A;  4GH8 A;  2D0K A;  4P3R A;  3I3R A;  4X5F A;  5HSU A;  8DFR A;  1DF7 A;  4NX6 A;  2LF1 A;  3UM6 A;  1QZF A;  1IA2 A;  3HJ3 A;  1RX3 A;  3ROA A;  3FS6 A;  5U26 A;  4ELE A;  4DP3 A;  5FDA A;  3KY8 A;  4Q67 A;  3S9U A;  1RB2 A;  3NRR A;  5HI6 A;  3NU0 A;  4KD7 A;  4X5J A;  1RX8 A;  3JWC A;  3NTZ A;  4LAH X;  4KEB A;  2G6V A;  4ELB A;  3JW3 A;  3NXR A;  4HOE A;  4H95 A;  4XT4 A;  1S3V A;  1J3I A;  1JUV A;  4OR7 A;  3IRO A;  3CL9 A;  1RX9 A;  4IXE D;  3FQZ A;  3QLW A;  1DAJ A;  4ECK A;  1RA8 A;  4PTH A;  1DRH A;  4EIL A;  3FY8 X;  3TQ8 A;  4X5I A;  5JA3 A;  1JOM A;  1DHI A;  3FL9 A;  3NXX A;  4KM2 A;  2W9T A;  3QYL A;  4QJC A;  3TQA A;  3UM8 A;  2ZZA A;  1IA3 A;  4KAK A;  1AO8 A;  4XT6 A;  4LAG X;  3FRE X;  1DHF A;  1RB3 A;  4X5H A;  4XRB A;  3SR5 X;  3KFY A;  4XEC X;  4I1N A;  1RA2 A;  2AZN A;  7DFR A;  1CZ3 A;  2W3V A;  1S3U A;  1U72 A;  5HQY A;  2BLC A;  4DDR A; 
#chains in the Genus database with same CATH topology
 4NX7 A;  3R33 A;  3QFX A;  3S7A A;  4EIZ A;  2W3M A;  4ELG A;  1DYJ A;  4Q6A A;  6DFR A;  3DAT A;  1RF7 A;  4QLF A;  5DXV A;  3GI2 A;  4LEK X;  5ECX A;  3KJS A;  1DIU A;  1DG7 A;  1DHJ A;  3DRC A;  3SRS X;  5HPB A;  5HT5 A;  4OSG A;  4KY4 A;  3DL6 A;  2O7P A;  3CD2 A;  4DFR A;  3EX8 A;  1DRE A;  3NXO A;  3EEL A;  4H97 A;  3S3V A;  3KJR A;  3RO9 A;  1AOE A;  4XT8 A;  3TD8 A;  1PDB A;  2XW7 A;  5HF2 X;  4QJZ D;  1MVT A;  3F0B X;  3K2H A;  3QG2 A;  3SA1 A;  3FQ0 A;  3K74 A;  5CCC A;  3SA2 A;  3VCO A;  1M7A A;  1DDS A;  3DGA A;  4LAE X;  4X5G A;  2JYB A;  3D80 A;  1J3K A;  1RX4 A;  4P66 A;  3IA5 A;  4KBN A;  5HVB A;  5HUI A;  3DFR A;  1LY3 A;  3NZ9 X;  3E0B A;  1RG7 A;  4PSS A;  3JVX A;  1DR3 A;  1OHK A;  1RA9 A;  1DR2 A;  1RX6 A;  2W9G A;  1DYR A;  3DAU A;  2OIP A;  4DPH A;  1DR7 A;  2BLA A;  2FZJ A;  3QLX A;  5HF0 X;  1HFP A;  2ANQ A;  2OBC A;  3NXT A;  3FQC A;  2HQP A;  5U27 A;  1M79 A;  2W3W A;  1HFQ A;  5ECC A;  2CD2 A;  3FY9 X;  5HQZ A;  3K45 A;  3JTW A;  4IXG X;  4FHB A;  3UM5 A;  3F0S X;  3QL0 A;  3KGY A;  3Q1H A;  5HT4 A;  3SRW X;  3QLR A;  3DG8 A;  3JWF A;  3ZPG A;  3NXV A;  1YHO A;  3L3R A;  1DDR A;  4KY8 A;  1ZDR A;  4G8Z X;  2W9S A;  1RX7 A;  3F8Z A;  4G95 A;  4P68 A;  1VDR A;  4Q0E A;  4XE6 X;  3JWM A;  3NZ6 X;  2INQ A;  1MVS A;  4EJ1 A;  3QYO A;  3F0X X;  3IX9 A;  4PSY A;  5E8Q A;  3SAI A;  3F91 A;  3GYF A;  2HM9 A;  1DRF A;  1BZF A;  2HXV A;  1AI9 A;  3FQO A;  4ELH A;  2W3B A;  4M7V A;  3M08 A;  4DPD A;  3EEK A;  3FQF A;  4PDJ A;  1OHJ A;  1VJ3 A;  3FQV A;  5DFR A;  4KYA A;  3F0Q X;  1DLR A;  4PST A;  3FL8 A;  2C2S A;  1DYI A;  4I13 A;  3QLZ A;  3EIG A;  1TDR A;  3EEM A;  4TU5 X;  4XT7 A;  1DR5 A;  4ELF A;  2H2Q A;  3EEJ A;  3INV A;  2W3A A;  3NZC X;  4M6J A;  3M09 A;  1DG5 A;  2BLB A;  1M78 A;  5HVE A;  3GHV A;  4KJK A;  2D5N A;  3JW5 A;  1DR1 A;  1S3W A;  3QLY A;  4H98 A;  1RD7 A;  3TQ9 A;  3NXY A;  1DIS A;  3FRF X;  1DR4 A;  1E26 A;  3JSU A;  3GHW A;  3QLS A;  4FGH A;  4CD2 A;  3F8Y A;  2KGK A;  3NZB X;  3SRR X;  1IA4 A;  3JWK A;  2BL9 A;  4KLX A;  1RX2 A;  2ANO A;  1S3Y A;  1CD2 A;  1LUD A;  4HOF A;  1RX1 A;  1PD9 A;  1J3J A;  3DL5 A;  3TQB A;  3GHC A;  3ZPC A;  3OCH A;  3FRA X;  4HOG A;  5CC9 A;  3IRN A;  4QHV A;  1RC4 A;  1KMV A;  3IRM A;  3N0H A;  1RE7 A;  3FRD X;  3HBB A;  4KM0 A;  3SH2 A;  4HA9 A;  4QLG A;  4H96 A;  2FZI A;  3SRQ X;  3NZD A;  1JOL A;  2DHF A;  4KNE A;  3CLB A;  5JG0 X;  3SQY X;  1RH3 A;  4KJL A;  4KJJ A;  3F0U X;  4Q0D A;  3SRU X;  5HSR A;  1KMS A;  4HA7 A;  4M6L A;  4PTJ A;  1KLK A;  2ITH A;  1U70 A;  1HFR A;  4RGC A;  2W9H A;  3CSE A;  1DYH A;  3FYW X;  3LG4 A;  2B3Z A;  1LY4 A;  4EIG A;  3QL3 A;  2DRC A;  3I8A X;  1DR6 A;  2L28 A;  3NZA X;  1DLS A;  2FZH A;  1PD8 A;  3FRB X;  3SGY A;  1BOZ A;  2QK8 A;  3FYV X;  1DRB A;  4M7U A;  3K47 A;  4M6K A;  3QGT A;  1D1G A;  5EAJ A;  1SEJ A;  3F0V X;  2CIG A;  4FGG A;  4M2X A;  1RA1 A;  1IA1 A;  4XT5 A;  3OAF A;  4G3M A;  4KL9 A;  4QLE A;  2P4G A;  3RG9 A;  1DG8 A;  1DRA A;  4KFJ A;  4QI9 A;  1RA3 A;  2C2T A;  4IXF X;  1RX5 A;  1U71 A;  3IA4 A;  2GD9 A;  3D84 X;  4P3Q A;  4GH8 A;  2D0K A;  4P3R A;  3I3R A;  4X5F A;  5HSU A;  8DFR A;  1DF7 A;  4NX6 A;  2LF1 A;  3UM6 A;  1QZF A;  1IA2 A;  3HJ3 A;  1RX3 A;  3ROA A;  3FS6 A;  5U26 A;  4ELE A;  4DP3 A;  5FDA A;  3KY8 A;  4Q67 A;  3S9U A;  1RB2 A;  3NRR A;  5HI6 A;  3NU0 A;  4KD7 A;  4X5J A;  1RX8 A;  3JWC A;  3NTZ A;  4LAH X;  4KEB A;  2G6V A;  4ELB A;  3JW3 A;  3NXR A;  4HOE A;  4H95 A;  4XT4 A;  1S3V A;  1J3I A;  1JUV A;  4OR7 A;  3IRO A;  3CL9 A;  1RX9 A;  4IXE D;  3FQZ A;  3QLW A;  1DAJ A;  4ECK A;  1RA8 A;  4PTH A;  1DRH A;  4EIL A;  3FY8 X;  3TQ8 A;  4X5I A;  5JA3 A;  1JOM A;  1DHI A;  3FL9 A;  3NXX A;  4KM2 A;  2W9T A;  3QYL A;  4QJC A;  3TQA A;  3UM8 A;  2ZZA A;  1IA3 A;  4KAK A;  1AO8 A;  4XT6 A;  4LAG X;  3FRE X;  1DHF A;  1RB3 A;  4X5H A;  4XRB A;  3SR5 X;  3KFY A;  4XEC X;  4I1N A;  1RA2 A;  2AZN A;  7DFR A;  1CZ3 A;  2W3V A;  1S3U A;  1U72 A;  5HQY A;  2BLC A;  4DDR A; 
#chains in the Genus database with same CATH homology
 4NX7 A;  3R33 A;  3QFX A;  3S7A A;  4EIZ A;  2W3M A;  4ELG A;  1DYJ A;  4Q6A A;  6DFR A;  3DAT A;  1RF7 A;  4QLF A;  5DXV A;  3GI2 A;  4LEK X;  5ECX A;  3KJS A;  1DIU A;  1DG7 A;  1DHJ A;  3DRC A;  3SRS X;  5HPB A;  5HT5 A;  4OSG A;  4KY4 A;  3DL6 A;  2O7P A;  3CD2 A;  4DFR A;  3EX8 A;  1DRE A;  3NXO A;  3EEL A;  4H97 A;  3S3V A;  3KJR A;  3RO9 A;  1AOE A;  4XT8 A;  3TD8 A;  1PDB A;  2XW7 A;  5HF2 X;  4QJZ D;  1MVT A;  3F0B X;  3K2H A;  3QG2 A;  3SA1 A;  3FQ0 A;  3K74 A;  5CCC A;  3SA2 A;  3VCO A;  1M7A A;  1DDS A;  3DGA A;  4LAE X;  4X5G A;  2JYB A;  3D80 A;  1J3K A;  1RX4 A;  4P66 A;  3IA5 A;  4KBN A;  5HVB A;  5HUI A;  3DFR A;  1LY3 A;  3NZ9 X;  3E0B A;  1RG7 A;  4PSS A;  3JVX A;  1DR3 A;  1OHK A;  1RA9 A;  1DR2 A;  1RX6 A;  2W9G A;  1DYR A;  3DAU A;  2OIP A;  4DPH A;  1DR7 A;  2BLA A;  2FZJ A;  3QLX A;  5HF0 X;  1HFP A;  2ANQ A;  2OBC A;  3NXT A;  3FQC A;  2HQP A;  5U27 A;  1M79 A;  2W3W A;  1HFQ A;  5ECC A;  2CD2 A;  3FY9 X;  5HQZ A;  3K45 A;  3JTW A;  4IXG X;  4FHB A;  3UM5 A;  3F0S X;  3QL0 A;  3KGY A;  3Q1H A;  5HT4 A;  3SRW X;  3QLR A;  3DG8 A;  3JWF A;  3ZPG A;  3NXV A;  1YHO A;  3L3R A;  1DDR A;  4KY8 A;  1ZDR A;  4G8Z X;  2W9S A;  1RX7 A;  3F8Z A;  4G95 A;  4P68 A;  1VDR A;  4Q0E A;  4XE6 X;  3JWM A;  3NZ6 X;  2INQ A;  1MVS A;  4EJ1 A;  3QYO A;  3F0X X;  3IX9 A;  4PSY A;  5E8Q A;  3SAI A;  3F91 A;  3GYF A;  2HM9 A;  1DRF A;  1BZF A;  2HXV A;  1AI9 A;  3FQO A;  4ELH A;  2W3B A;  4M7V A;  3M08 A;  4DPD A;  3EEK A;  3FQF A;  4PDJ A;  1OHJ A;  1VJ3 A;  3FQV A;  5DFR A;  4KYA A;  3F0Q X;  1DLR A;  4PST A;  3FL8 A;  2C2S A;  1DYI A;  4I13 A;  3QLZ A;  3EIG A;  1TDR A;  3EEM A;  4TU5 X;  4XT7 A;  1DR5 A;  4ELF A;  2H2Q A;  3EEJ A;  3INV A;  2W3A A;  3NZC X;  4M6J A;  3M09 A;  1DG5 A;  2BLB A;  1M78 A;  5HVE A;  3GHV A;  4KJK A;  2D5N A;  3JW5 A;  1DR1 A;  1S3W A;  3QLY A;  4H98 A;  1RD7 A;  3TQ9 A;  3NXY A;  1DIS A;  3FRF X;  1DR4 A;  1E26 A;  3JSU A;  3GHW A;  3QLS A;  4FGH A;  4CD2 A;  3F8Y A;  2KGK A;  3NZB X;  3SRR X;  1IA4 A;  3JWK A;  2BL9 A;  4KLX A;  1RX2 A;  2ANO A;  1S3Y A;  1CD2 A;  1LUD A;  4HOF A;  1RX1 A;  1PD9 A;  1J3J A;  3DL5 A;  3TQB A;  3GHC A;  3ZPC A;  3OCH A;  3FRA X;  4HOG A;  5CC9 A;  3IRN A;  4QHV A;  1RC4 A;  1KMV A;  3IRM A;  3N0H A;  1RE7 A;  3FRD X;  3HBB A;  4KM0 A;  3SH2 A;  4HA9 A;  4QLG A;  4H96 A;  2FZI A;  3SRQ X;  3NZD A;  1JOL A;  2DHF A;  4KNE A;  3CLB A;  5JG0 X;  3SQY X;  1RH3 A;  4KJL A;  4KJJ A;  3F0U X;  4Q0D A;  3SRU X;  5HSR A;  1KMS A;  4HA7 A;  4M6L A;  4PTJ A;  1KLK A;  2ITH A;  1U70 A;  1HFR A;  4RGC A;  2W9H A;  3CSE A;  1DYH A;  3FYW X;  3LG4 A;  2B3Z A;  1LY4 A;  4EIG A;  3QL3 A;  2DRC A;  3I8A X;  1DR6 A;  2L28 A;  3NZA X;  1DLS A;  2FZH A;  1PD8 A;  3FRB X;  3SGY A;  1BOZ A;  2QK8 A;  3FYV X;  1DRB A;  4M7U A;  3K47 A;  4M6K A;  3QGT A;  1D1G A;  5EAJ A;  1SEJ A;  3F0V X;  2CIG A;  4FGG A;  4M2X A;  1RA1 A;  1IA1 A;  4XT5 A;  3OAF A;  4G3M A;  4KL9 A;  4QLE A;  2P4G A;  3RG9 A;  1DG8 A;  1DRA A;  4KFJ A;  4QI9 A;  1RA3 A;  2C2T A;  4IXF X;  1RX5 A;  1U71 A;  3IA4 A;  2GD9 A;  3D84 X;  4P3Q A;  4GH8 A;  2D0K A;  4P3R A;  3I3R A;  4X5F A;  5HSU A;  8DFR A;  1DF7 A;  4NX6 A;  2LF1 A;  3UM6 A;  1QZF A;  1IA2 A;  3HJ3 A;  1RX3 A;  3ROA A;  3FS6 A;  5U26 A;  4ELE A;  4DP3 A;  5FDA A;  3KY8 A;  4Q67 A;  3S9U A;  1RB2 A;  3NRR A;  5HI6 A;  3NU0 A;  4KD7 A;  4X5J A;  1RX8 A;  3JWC A;  3NTZ A;  4LAH X;  4KEB A;  2G6V A;  4ELB A;  3JW3 A;  3NXR A;  4HOE A;  4H95 A;  4XT4 A;  1S3V A;  1J3I A;  1JUV A;  4OR7 A;  3IRO A;  3CL9 A;  1RX9 A;  4IXE D;  3FQZ A;  3QLW A;  1DAJ A;  4ECK A;  1RA8 A;  4PTH A;  1DRH A;  4EIL A;  3FY8 X;  3TQ8 A;  4X5I A;  5JA3 A;  1JOM A;  1DHI A;  3FL9 A;  3NXX A;  4KM2 A;  2W9T A;  3QYL A;  4QJC A;  3TQA A;  3UM8 A;  2ZZA A;  1IA3 A;  4KAK A;  1AO8 A;  4XT6 A;  4LAG X;  3FRE X;  1DHF A;  1RB3 A;  4X5H A;  4XRB A;  3SR5 X;  3KFY A;  4XEC X;  4I1N A;  1RA2 A;  2AZN A;  7DFR A;  1CZ3 A;  2W3V A;  1S3U A;  1U72 A;  5HQY A;  2BLC A;  4DDR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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