4ELHA

Structure-activity relationship guides enantiomeric preference among potent inhibitors of b. anthracis dihydrofolate reductase
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
166
structure length
166
Chain Sequence
MIVSFMVAMDENRVIGKDNNLPWRLPSELQYVKKTTMGHPLIMGRKNYEAIGRPLPGRRNIIVTRNEGYHVEGCEVAHSVEEVFELCKNEEEIFIFGGAQIYDLFLPYVDKLYITKIHHAFEGDTFFPEMDMTNWKEVFVEKGLTDEKNPYTYYYHVYEKQQLVPR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductase.
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Bacillus anthracis
molecule keywords Dihydrofolate reductase
total genus 41
structure length 166
sequence length 166
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2012-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4elhA00
4DPDA 3F0BX 4KAKA 3FQOA 4KEBA 5HSRA 5EAJA 4EIZA 4HA7A 3NXOA 4KJKA 4EILA 5ECXA 3INVA 3F0XX 4PTJA 1DG5A 3QLZA 3GHCA 3EEMA 3JWKA 4HOFA 4DP3A 3FY9X 4PSYA 1DRAA 1PD9A 3FY8X 5U27A 1M79A 2G6VA 3L3RA 3UM5A 1JOMA 2CD2A 4PDJA 4FHBA 3EIGA 2W3BA 4XT7A 1RE7A 3NXYA 3NXVA 1M78A 3K74A 3SA1A 1DR3A 2CIGA 2DRCA 1KLKA 5HQZA 3QGTA 4Q0DA 4LAHX 1RG7A 2H2QA 3IRNA 4HA9A 3JW3A 2FZIA 2ANQA 3FRBX 3QL3A 1RX4A 3FYWX 1S3VA 1DLSA 3IA5A 1HFPA 5CCCA 1KMVA 3EEKA 1RD7A 4KBNA 1DR5A 1TDRA 2QK8A 3FQVA 1IA4A 2W9GA 1DR4A 4QJZD 3GI2A 3SRRX 1OHKA 1MVSA 3QLRA 3ZPCA 1M7AA 4ELBA 4X5GA 3SA2A 3K2HA 2B3ZA 3QG2A 1RA9A 3FQCA 4ECKA 3NZ6X 1RF7A 3DL6A 1RX7A 4QI9A 2FZHA 6DFRA 3HJ3A 2W3WA 2W9SA 1J3KA 4X5FA 3FQ0A 1RX8A 3N0HA 4H96A 3JWMA 4XT4A 4I13A 5HVEA 3EX8A 4ELEA 5HT5A 4ELFA 1S3UA 4M7UA 1HFRA 3EEJA 3FRFX 4FGHA 1J3JA 4OSGA 3TQBA 5HI6A 1HFQA 3NXXA 2ZZAA 5HVBA 3D84X 2W3AA 1U72A 3FYVX 3NZ9X 3FL9A 3QYLA 4QJCA 5FDAA 4IXGX 4LAEX 3F8YA 3IROA 4KD7A 1DG8A 3FQFA 3GHVA 3M09A 5HPBA 4PSTA 1E26A 3SGYA 1DYRA 1RC4A 4X5IA 3JTWA 3KY8A 4KY4A 4QLEA 3SRSX 1DRBA 3CSEA 3NU0A 3HBBA 2AZNA 3SRQX 2OBCA 1LY3A 1SEJA 4P66A 4HOGA 4IXED 3CLBA 5U26A 1DHFA 3LG4A 1S3WA 3DATA 3DG8A 2FZJA 3JVXA 3DAUA 3F0SX 1RB2A 2XW7A 3VCOA 3KGYA 1JOLA 4KL9A 1QZFA 1VDRA 5HSUA 2C2SA 2HXVA 2D5NA 3NRRA 2HQPA 3F0QX 1BOZA 3FREX 1U71A 3I3RA 4QLFA 4KJLA 3KJRA 3S7AA 4KYAA 3UM8A 4TU5X 3CD2A 1DR1A 3DGAA 2L28A 2DHFA 3IX9A 4NX7A 2W3VA 1DHIA 5E8QA 5HUIA 1PD8A 1MVTA 4OR7A 1DYIA 1DR2A 3DL5A 3FQZA 4QHVA 3F0VX 3K47A 1AI9A 3NZCX 3I8AX 2BL9A 1S3YA 1ZDRA 4EIGA 7DFRA 3NZDA 3D80A 1DAJA 4Q6AA 1RX9A 3KJSA 4PTHA 4LEKX 4KM2A 4XRBA 1DYHA 1RA8A 3QLWA 1OHJA 4H95A 4XT8A 3IA4A 4XT5A 4HOEA 1BZFA 2JYBA 2O7PA 3QL0A 3UM6A 4LAGX 4ELHA 2BLCA 1CZ3A 3ZPGA 1RA3A 3OAFA 1DLRA 4G95A 3TD8A 1RH3A 3DRCA 3KFYA 3S3VA 3NXTA 3SQYX 1DRFA 3JW5A 3FL8A 4KJJA 1RX1A 4G3MA 2C2TA 1RX5A 3TQAA 4H97A 8DFRA 2KGKA 2BLAA 3SRWX 2ITHA 1U70A 3TQ9A 3RO9A 3M08A 1DF7A 1D1GA 3QLYA 4P68A 5HT4A 1AOEA 2W9TA 3K45A 1DDSA 3QFXA 3EELA 3S9UA 4H98A 1AO8A 1RX2A 4XT6A 2P4GA 3IRMA 2INQA 4M6KA 1RX6A 5DFRA 3FRAX 5JG0X 3GYFA 4GH8A 4Q67A 5HQYA 1DISA 4FGGA 3F91A 3JWCA 4X5HA 3NXRA 4RGCA 4DPHA 5HF0X 4G8ZX 5DXVA 3SAIA 1DR7A 3QLXA 1DHJA 3QLSA 4ELGA 3R33A 3NTZA 4Q0EA 2GD9A 4EJ1A 2HM9A 4KLXA 1YHOA 4KM0A 3FRDX 1CD2A 3E0BA 3TQ8A 3JSUA 5CC9A 4M6JA 1RB3A 3OCHA 4KNEA 4NX6A 5JA3A 2BLBA 4M6LA 4QLGA 3QYOA 4DDRA 1LUDA 1VJ3A 1IA1A 3NZBX 3NZAX 4CD2A 1DR6A 4PSSA 1RX3A 1KMSA 1DREA 1RA2A 1DDRA 4XECX 1IA2A 3ROAA 3JWFA 1PDBA 1DG7A 2OIPA 3DFRA 3SR5X 2ANOA 3GHWA 2D0KA 2W9HA 1DIUA 5ECCA 3RG9A 4XE6X 3F8ZA 2W3MA 3Q1HA 1J3IA 3CL9A 4I1NA 4P3RA 3SRUX 2LF1A 4KY8A 4IXFX 4M7VA 1DYJA 1JUVA 4DFRA 5HF2X 1IA3A 3F0UX 1RA1A 3FS6A 4M2XA 4KFJA 3SH2A 1LY4A 4P3QA 1DRHA 4X5JA
chains in the Genus database with same CATH superfamily
4DPDA 3F0BX 4KAKA 3FQOA 4KEBA 5HSRA 5EAJA 4EIZA 4HA7A 3NXOA 4KJKA 4EILA 5ECXA 3INVA 3F0XX 4PTJA 1DG5A 3QLZA 3GHCA 3EEMA 3JWKA 4HOFA 4DP3A 3FY9X 4PSYA 1DRAA 1PD9A 3FY8X 5U27A 1M79A 2G6VA 3L3RA 3UM5A 1JOMA 2CD2A 4PDJA 4FHBA 3EIGA 2W3BA 4XT7A 1RE7A 3NXYA 3NXVA 1M78A 3K74A 3SA1A 1DR3A 2CIGA 2DRCA 1KLKA 5HQZA 3QGTA 4Q0DA 4LAHX 1RG7A 2H2QA 3IRNA 4HA9A 3JW3A 2FZIA 2ANQA 3FRBX 3QL3A 1RX4A 3FYWX 1S3VA 1DLSA 3IA5A 1HFPA 5CCCA 1KMVA 3EEKA 1RD7A 4KBNA 1DR5A 1TDRA 2QK8A 3FQVA 1IA4A 2W9GA 1DR4A 4QJZD 3GI2A 3SRRX 1OHKA 1MVSA 3QLRA 3ZPCA 1M7AA 4ELBA 4X5GA 3SA2A 3K2HA 2B3ZA 3QG2A 1RA9A 3FQCA 4ECKA 3NZ6X 1RF7A 3DL6A 1RX7A 4QI9A 2FZHA 6DFRA 3HJ3A 2W3WA 2W9SA 1J3KA 4X5FA 3FQ0A 1RX8A 3N0HA 4H96A 3JWMA 4XT4A 4I13A 5HVEA 3EX8A 4ELEA 5HT5A 4ELFA 1S3UA 4M7UA 1HFRA 3EEJA 3FRFX 4FGHA 1J3JA 4OSGA 3TQBA 5HI6A 1HFQA 3NXXA 2ZZAA 5HVBA 3D84X 2W3AA 1U72A 3FYVX 3NZ9X 3FL9A 3QYLA 4QJCA 5FDAA 4IXGX 4LAEX 3F8YA 3IROA 4KD7A 1DG8A 3FQFA 3GHVA 3M09A 5HPBA 4PSTA 1E26A 3SGYA 1DYRA 1RC4A 4X5IA 3JTWA 3KY8A 4KY4A 4QLEA 3SRSX 1DRBA 3CSEA 3NU0A 3HBBA 2AZNA 3SRQX 2OBCA 1LY3A 1SEJA 4P66A 4HOGA 4IXED 3CLBA 5U26A 1DHFA 3LG4A 1S3WA 3DATA 3DG8A 2FZJA 3JVXA 3DAUA 3F0SX 1RB2A 2XW7A 3VCOA 3KGYA 1JOLA 4KL9A 1QZFA 1VDRA 5HSUA 2C2SA 2HXVA 2D5NA 3NRRA 2HQPA 3F0QX 1BOZA 3FREX 1U71A 3I3RA 4QLFA 4KJLA 3KJRA 3S7AA 4KYAA 3UM8A 4TU5X 3CD2A 1DR1A 3DGAA 2L28A 2DHFA 3IX9A 4NX7A 2W3VA 1DHIA 5E8QA 5HUIA 1PD8A 1MVTA 4OR7A 1DYIA 1DR2A 3DL5A 3FQZA 4QHVA 3F0VX 3K47A 1AI9A 3NZCX 3I8AX 2BL9A 1S3YA 1ZDRA 4EIGA 7DFRA 3NZDA 3D80A 1DAJA 4Q6AA 1RX9A 3KJSA 4PTHA 4LEKX 4KM2A 4XRBA 1DYHA 1RA8A 3QLWA 1OHJA 4H95A 4XT8A 3IA4A 4XT5A 4HOEA 1BZFA 2JYBA 2O7PA 3QL0A 3UM6A 4LAGX 4ELHA 2BLCA 1CZ3A 3ZPGA 1RA3A 3OAFA 1DLRA 4G95A 3TD8A 1RH3A 3DRCA 3KFYA 3S3VA 3NXTA 3SQYX 1DRFA 3JW5A 3FL8A 4KJJA 1RX1A 4G3MA 2C2TA 1RX5A 3TQAA 4H97A 8DFRA 2KGKA 2BLAA 3SRWX 2ITHA 1U70A 3TQ9A 3RO9A 3M08A 1DF7A 1D1GA 3QLYA 4P68A 5HT4A 1AOEA 2W9TA 3K45A 1DDSA 3QFXA 3EELA 3S9UA 4H98A 1AO8A 1RX2A 4XT6A 2P4GA 3IRMA 2INQA 4M6KA 1RX6A 5DFRA 3FRAX 5JG0X 3GYFA 4GH8A 4Q67A 5HQYA 1DISA 4FGGA 3F91A 3JWCA 4X5HA 3NXRA 4RGCA 4DPHA 5HF0X 4G8ZX 5DXVA 3SAIA 1DR7A 3QLXA 1DHJA 3QLSA 4ELGA 3R33A 3NTZA 4Q0EA 2GD9A 4EJ1A 2HM9A 4KLXA 1YHOA 4KM0A 3FRDX 1CD2A 3E0BA 3TQ8A 3JSUA 5CC9A 4M6JA 1RB3A 3OCHA 4KNEA 4NX6A 5JA3A 2BLBA 4M6LA 4QLGA 3QYOA 4DDRA 1LUDA 1VJ3A 1IA1A 3NZBX 3NZAX 4CD2A 1DR6A 4PSSA 1RX3A 1KMSA 1DREA 1RA2A 1DDRA 4XECX 1IA2A 3ROAA 3JWFA 1PDBA 1DG7A 2OIPA 3DFRA 3SR5X 2ANOA 3GHWA 2D0KA 2W9HA 1DIUA 5ECCA 3RG9A 4XE6X 3F8ZA 2W3MA 3Q1HA 1J3IA 3CL9A 4I1NA 4P3RA 3SRUX 2LF1A 4KY8A 4IXFX 4M7VA 1DYJA 1JUVA 4DFRA 5HF2X 1IA3A 3F0UX 1RA1A 3FS6A 4M2XA 4KFJA 3SH2A 1LY4A 4P3QA 1DRHA 4X5JA
chains in the Genus database with same CATH topology
4DPDA 3F0BX 4KAKA 3FQOA 4KEBA 5HSRA 5EAJA 4EIZA 4HA7A 3NXOA 4KJKA 4EILA 5ECXA 3INVA 3F0XX 4PTJA 1DG5A 3QLZA 3GHCA 3EEMA 3JWKA 4HOFA 4DP3A 3FY9X 4PSYA 1DRAA 1PD9A 3FY8X 5U27A 1M79A 2G6VA 3L3RA 3UM5A 1JOMA 2CD2A 4PDJA 4FHBA 3EIGA 2W3BA 4XT7A 1RE7A 3NXYA 3NXVA 1M78A 3K74A 3SA1A 1DR3A 2CIGA 2DRCA 1KLKA 5HQZA 3QGTA 4Q0DA 4LAHX 1RG7A 2H2QA 3IRNA 4HA9A 3JW3A 2FZIA 2ANQA 3FRBX 3QL3A 1RX4A 3FYWX 1S3VA 1DLSA 3IA5A 1HFPA 5CCCA 1KMVA 3EEKA 1RD7A 4KBNA 1DR5A 1TDRA 2QK8A 3FQVA 1IA4A 2W9GA 1DR4A 4QJZD 3GI2A 3SRRX 1OHKA 1MVSA 3QLRA 3ZPCA 1M7AA 4ELBA 4X5GA 3SA2A 3K2HA 2B3ZA 3QG2A 1RA9A 3FQCA 4ECKA 3NZ6X 1RF7A 3DL6A 1RX7A 4QI9A 2FZHA 6DFRA 3HJ3A 2W3WA 2W9SA 1J3KA 4X5FA 3FQ0A 1RX8A 3N0HA 4H96A 3JWMA 4XT4A 4I13A 5HVEA 3EX8A 4ELEA 5HT5A 4ELFA 1S3UA 4M7UA 1HFRA 3EEJA 3FRFX 4FGHA 1J3JA 4OSGA 3TQBA 5HI6A 1HFQA 3NXXA 2ZZAA 5HVBA 3D84X 2W3AA 1U72A 3FYVX 3NZ9X 3FL9A 3QYLA 4QJCA 5FDAA 4IXGX 4LAEX 3F8YA 3IROA 4KD7A 1DG8A 3FQFA 3GHVA 3M09A 5HPBA 4PSTA 1E26A 3SGYA 1DYRA 1RC4A 4X5IA 3JTWA 3KY8A 4KY4A 4QLEA 3SRSX 1DRBA 3CSEA 3NU0A 3HBBA 2AZNA 3SRQX 2OBCA 1LY3A 1SEJA 4P66A 4HOGA 4IXED 3CLBA 5U26A 1DHFA 3LG4A 1S3WA 3DATA 3DG8A 2FZJA 3JVXA 3DAUA 3F0SX 1RB2A 2XW7A 3VCOA 3KGYA 1JOLA 4KL9A 1QZFA 1VDRA 5HSUA 2C2SA 2HXVA 2D5NA 3NRRA 2HQPA 3F0QX 1BOZA 3FREX 1U71A 3I3RA 4QLFA 4KJLA 3KJRA 3S7AA 4KYAA 3UM8A 4TU5X 3CD2A 1DR1A 3DGAA 2L28A 2DHFA 3IX9A 4NX7A 2W3VA 1DHIA 5E8QA 5HUIA 1PD8A 1MVTA 4OR7A 1DYIA 1DR2A 3DL5A 3FQZA 4QHVA 3F0VX 3K47A 1AI9A 3NZCX 3I8AX 2BL9A 1S3YA 1ZDRA 4EIGA 7DFRA 3NZDA 3D80A 1DAJA 4Q6AA 1RX9A 3KJSA 4PTHA 4LEKX 4KM2A 4XRBA 1DYHA 1RA8A 3QLWA 1OHJA 4H95A 4XT8A 3IA4A 4XT5A 4HOEA 1BZFA 2JYBA 2O7PA 3QL0A 3UM6A 4LAGX 4ELHA 2BLCA 1CZ3A 3ZPGA 1RA3A 3OAFA 1DLRA 4G95A 3TD8A 1RH3A 3DRCA 3KFYA 3S3VA 3NXTA 3SQYX 1DRFA 3JW5A 3FL8A 4KJJA 1RX1A 4G3MA 2C2TA 1RX5A 3TQAA 4H97A 8DFRA 2KGKA 2BLAA 3SRWX 2ITHA 1U70A 3TQ9A 3RO9A 3M08A 1DF7A 1D1GA 3QLYA 4P68A 5HT4A 1AOEA 2W9TA 3K45A 1DDSA 3QFXA 3EELA 3S9UA 4H98A 1AO8A 1RX2A 4XT6A 2P4GA 3IRMA 2INQA 4M6KA 1RX6A 5DFRA 3FRAX 5JG0X 3GYFA 4GH8A 4Q67A 5HQYA 1DISA 4FGGA 3F91A 3JWCA 4X5HA 3NXRA 4RGCA 4DPHA 5HF0X 4G8ZX 5DXVA 3SAIA 1DR7A 3QLXA 1DHJA 3QLSA 4ELGA 3R33A 3NTZA 4Q0EA 2GD9A 4EJ1A 2HM9A 4KLXA 1YHOA 4KM0A 3FRDX 1CD2A 3E0BA 3TQ8A 3JSUA 5CC9A 4M6JA 1RB3A 3OCHA 4KNEA 4NX6A 5JA3A 2BLBA 4M6LA 4QLGA 3QYOA 4DDRA 1LUDA 1VJ3A 1IA1A 3NZBX 3NZAX 4CD2A 1DR6A 4PSSA 1RX3A 1KMSA 1DREA 1RA2A 1DDRA 4XECX 1IA2A 3ROAA 3JWFA 1PDBA 1DG7A 2OIPA 3DFRA 3SR5X 2ANOA 3GHWA 2D0KA 2W9HA 1DIUA 5ECCA 3RG9A 4XE6X 3F8ZA 2W3MA 3Q1HA 1J3IA 3CL9A 4I1NA 4P3RA 3SRUX 2LF1A 4KY8A 4IXFX 4M7VA 1DYJA 1JUVA 4DFRA 5HF2X 1IA3A 3F0UX 1RA1A 3FS6A 4M2XA 4KFJA 3SH2A 1LY4A 4P3QA 1DRHA 4X5JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DPD A;  3F0B X;  4KAK A;  3FQO A;  4KEB A;  5HSR A;  5EAJ A;  4EIZ A;  4HA7 A;  3NXO A;  4KJK A;  4EIL A;  5ECX A;  3INV A;  3F0X X;  4PTJ A;  1DG5 A;  3QLZ A;  3GHC A;  3EEM A;  3JWK A;  4HOF A;  4DP3 A;  3FY9 X;  4PSY A;  1DRA A;  1PD9 A;  3FY8 X;  5U27 A;  1M79 A;  2G6V A;  3L3R A;  3UM5 A;  1JOM A;  2CD2 A;  4PDJ A;  4FHB A;  3EIG A;  2W3B A;  4XT7 A;  1RE7 A;  3NXY A;  3NXV A;  1M78 A;  3K74 A;  3SA1 A;  1DR3 A;  2CIG A;  2DRC A;  1KLK A;  5HQZ A;  3QGT A;  4Q0D A;  4LAH X;  1RG7 A;  2H2Q A;  3IRN A;  4HA9 A;  3JW3 A;  2FZI A;  2ANQ A;  3FRB X;  3QL3 A;  1RX4 A;  3FYW X;  1S3V A;  1DLS A;  3IA5 A;  1HFP A;  5CCC A;  1KMV A;  3EEK A;  1RD7 A;  4KBN A;  1DR5 A;  1TDR A;  2QK8 A;  3FQV A;  1IA4 A;  2W9G A;  1DR4 A;  4QJZ D;  3GI2 A;  3SRR X;  1OHK A;  1MVS A;  3QLR A;  3ZPC A;  1M7A A;  4ELB A;  4X5G A;  3SA2 A;  3K2H A;  2B3Z A;  3QG2 A;  1RA9 A;  3FQC A;  4ECK A;  3NZ6 X;  1RF7 A;  3DL6 A;  1RX7 A;  4QI9 A;  2FZH A;  6DFR A;  3HJ3 A;  2W3W A;  2W9S A;  1J3K A;  4X5F A;  3FQ0 A;  1RX8 A;  3N0H A;  4H96 A;  3JWM A;  4XT4 A;  4I13 A;  5HVE A;  3EX8 A;  4ELE A;  5HT5 A;  4ELF A;  1S3U A;  4M7U A;  1HFR A;  3EEJ A;  3FRF X;  4FGH A;  1J3J A;  4OSG A;  3TQB A;  5HI6 A;  1HFQ A;  3NXX A;  2ZZA A;  5HVB A;  3D84 X;  2W3A A;  1U72 A;  3FYV X;  3NZ9 X;  3FL9 A;  3QYL A;  4QJC A;  5FDA A;  4IXG X;  4LAE X;  3F8Y A;  3IRO A;  4KD7 A;  1DG8 A;  3FQF A;  3GHV A;  3M09 A;  5HPB A;  4PST A;  1E26 A;  3SGY A;  1DYR A;  1RC4 A;  4X5I A;  3JTW A;  3KY8 A;  4KY4 A;  4QLE A;  3SRS X;  1DRB A;  3CSE A;  3NU0 A;  3HBB A;  2AZN A;  3SRQ X;  2OBC A;  1LY3 A;  1SEJ A;  4P66 A;  4HOG A;  4IXE D;  3CLB A;  5U26 A;  1DHF A;  3LG4 A;  1S3W A;  3DAT A;  3DG8 A;  2FZJ A;  3JVX A;  3DAU A;  3F0S X;  1RB2 A;  2XW7 A;  3VCO A;  3KGY A;  1JOL A;  4KL9 A;  1QZF A;  1VDR A;  5HSU A;  2C2S A;  2HXV A;  2D5N A;  3NRR A;  2HQP A;  3F0Q X;  1BOZ A;  3FRE X;  1U71 A;  3I3R A;  4QLF A;  4KJL A;  3KJR A;  3S7A A;  4KYA A;  3UM8 A;  4TU5 X;  3CD2 A;  1DR1 A;  3DGA A;  2L28 A;  2DHF A;  3IX9 A;  4NX7 A;  2W3V A;  1DHI A;  5E8Q A;  5HUI A;  1PD8 A;  1MVT A;  4OR7 A;  1DYI A;  1DR2 A;  3DL5 A;  3FQZ A;  4QHV A;  3F0V X;  3K47 A;  1AI9 A;  3NZC X;  3I8A X;  2BL9 A;  1S3Y A;  1ZDR A;  4EIG A;  7DFR A;  3NZD A;  3D80 A;  1DAJ A;  4Q6A A;  1RX9 A;  3KJS A;  4PTH A;  4LEK X;  4KM2 A;  4XRB A;  1DYH A;  1RA8 A;  3QLW A;  1OHJ A;  4H95 A;  4XT8 A;  3IA4 A;  4XT5 A;  4HOE A;  1BZF A;  2JYB A;  2O7P A;  3QL0 A;  3UM6 A;  4LAG X;  4ELH A;  2BLC A;  1CZ3 A;  3ZPG A;  1RA3 A;  3OAF A;  1DLR A;  4G95 A;  3TD8 A;  1RH3 A;  3DRC A;  3KFY A;  3S3V A;  3NXT A;  3SQY X;  1DRF A;  3JW5 A;  3FL8 A;  4KJJ A;  1RX1 A;  4G3M A;  2C2T A;  1RX5 A;  3TQA A;  4H97 A;  8DFR A;  2KGK A;  2BLA A;  3SRW X;  2ITH A;  1U70 A;  3TQ9 A;  3RO9 A;  3M08 A;  1DF7 A;  1D1G A;  3QLY A;  4P68 A;  5HT4 A;  1AOE A;  2W9T A;  3K45 A;  1DDS A;  3QFX A;  3EEL A;  3S9U A;  4H98 A;  1AO8 A;  1RX2 A;  4XT6 A;  2P4G A;  3IRM A;  2INQ A;  4M6K A;  1RX6 A;  5DFR A;  3FRA X;  5JG0 X;  3GYF A;  4GH8 A;  4Q67 A;  5HQY A;  1DIS A;  4FGG A;  3F91 A;  3JWC A;  4X5H A;  3NXR A;  4RGC A;  4DPH A;  5HF0 X;  4G8Z X;  5DXV A;  3SAI A;  1DR7 A;  3QLX A;  1DHJ A;  3QLS A;  4ELG A;  3R33 A;  3NTZ A;  4Q0E A;  2GD9 A;  4EJ1 A;  2HM9 A;  4KLX A;  1YHO A;  4KM0 A;  3FRD X;  1CD2 A;  3E0B A;  3TQ8 A;  3JSU A;  5CC9 A;  4M6J A;  1RB3 A;  3OCH A;  4KNE A;  4NX6 A;  5JA3 A;  2BLB A;  4M6L A;  4QLG A;  3QYO A;  4DDR A;  1LUD A;  1VJ3 A;  1IA1 A;  3NZB X;  3NZA X;  4CD2 A;  1DR6 A;  4PSS A;  1RX3 A;  1KMS A;  1DRE A;  1RA2 A;  1DDR A;  4XEC X;  1IA2 A;  3ROA A;  3JWF A;  1PDB A;  1DG7 A;  2OIP A;  3DFR A;  3SR5 X;  2ANO A;  3GHW A;  2D0K A;  2W9H A;  1DIU A;  5ECC A;  3RG9 A;  4XE6 X;  3F8Z A;  2W3M A;  3Q1H A;  1J3I A;  3CL9 A;  4I1N A;  4P3R A;  3SRU X;  2LF1 A;  4KY8 A;  4IXF X;  4M7V A;  1DYJ A;  1JUV A;  4DFR A;  5HF2 X;  1IA3 A;  3F0U X;  1RA1 A;  3FS6 A;  4M2X A;  4KFJ A;  3SH2 A;  1LY4 A;  4P3Q A;  1DRH A;  4X5J A; 
#chains in the Genus database with same CATH topology
 4DPD A;  3F0B X;  4KAK A;  3FQO A;  4KEB A;  5HSR A;  5EAJ A;  4EIZ A;  4HA7 A;  3NXO A;  4KJK A;  4EIL A;  5ECX A;  3INV A;  3F0X X;  4PTJ A;  1DG5 A;  3QLZ A;  3GHC A;  3EEM A;  3JWK A;  4HOF A;  4DP3 A;  3FY9 X;  4PSY A;  1DRA A;  1PD9 A;  3FY8 X;  5U27 A;  1M79 A;  2G6V A;  3L3R A;  3UM5 A;  1JOM A;  2CD2 A;  4PDJ A;  4FHB A;  3EIG A;  2W3B A;  4XT7 A;  1RE7 A;  3NXY A;  3NXV A;  1M78 A;  3K74 A;  3SA1 A;  1DR3 A;  2CIG A;  2DRC A;  1KLK A;  5HQZ A;  3QGT A;  4Q0D A;  4LAH X;  1RG7 A;  2H2Q A;  3IRN A;  4HA9 A;  3JW3 A;  2FZI A;  2ANQ A;  3FRB X;  3QL3 A;  1RX4 A;  3FYW X;  1S3V A;  1DLS A;  3IA5 A;  1HFP A;  5CCC A;  1KMV A;  3EEK A;  1RD7 A;  4KBN A;  1DR5 A;  1TDR A;  2QK8 A;  3FQV A;  1IA4 A;  2W9G A;  1DR4 A;  4QJZ D;  3GI2 A;  3SRR X;  1OHK A;  1MVS A;  3QLR A;  3ZPC A;  1M7A A;  4ELB A;  4X5G A;  3SA2 A;  3K2H A;  2B3Z A;  3QG2 A;  1RA9 A;  3FQC A;  4ECK A;  3NZ6 X;  1RF7 A;  3DL6 A;  1RX7 A;  4QI9 A;  2FZH A;  6DFR A;  3HJ3 A;  2W3W A;  2W9S A;  1J3K A;  4X5F A;  3FQ0 A;  1RX8 A;  3N0H A;  4H96 A;  3JWM A;  4XT4 A;  4I13 A;  5HVE A;  3EX8 A;  4ELE A;  5HT5 A;  4ELF A;  1S3U A;  4M7U A;  1HFR A;  3EEJ A;  3FRF X;  4FGH A;  1J3J A;  4OSG A;  3TQB A;  5HI6 A;  1HFQ A;  3NXX A;  2ZZA A;  5HVB A;  3D84 X;  2W3A A;  1U72 A;  3FYV X;  3NZ9 X;  3FL9 A;  3QYL A;  4QJC A;  5FDA A;  4IXG X;  4LAE X;  3F8Y A;  3IRO A;  4KD7 A;  1DG8 A;  3FQF A;  3GHV A;  3M09 A;  5HPB A;  4PST A;  1E26 A;  3SGY A;  1DYR A;  1RC4 A;  4X5I A;  3JTW A;  3KY8 A;  4KY4 A;  4QLE A;  3SRS X;  1DRB A;  3CSE A;  3NU0 A;  3HBB A;  2AZN A;  3SRQ X;  2OBC A;  1LY3 A;  1SEJ A;  4P66 A;  4HOG A;  4IXE D;  3CLB A;  5U26 A;  1DHF A;  3LG4 A;  1S3W A;  3DAT A;  3DG8 A;  2FZJ A;  3JVX A;  3DAU A;  3F0S X;  1RB2 A;  2XW7 A;  3VCO A;  3KGY A;  1JOL A;  4KL9 A;  1QZF A;  1VDR A;  5HSU A;  2C2S A;  2HXV A;  2D5N A;  3NRR A;  2HQP A;  3F0Q X;  1BOZ A;  3FRE X;  1U71 A;  3I3R A;  4QLF A;  4KJL A;  3KJR A;  3S7A A;  4KYA A;  3UM8 A;  4TU5 X;  3CD2 A;  1DR1 A;  3DGA A;  2L28 A;  2DHF A;  3IX9 A;  4NX7 A;  2W3V A;  1DHI A;  5E8Q A;  5HUI A;  1PD8 A;  1MVT A;  4OR7 A;  1DYI A;  1DR2 A;  3DL5 A;  3FQZ A;  4QHV A;  3F0V X;  3K47 A;  1AI9 A;  3NZC X;  3I8A X;  2BL9 A;  1S3Y A;  1ZDR A;  4EIG A;  7DFR A;  3NZD A;  3D80 A;  1DAJ A;  4Q6A A;  1RX9 A;  3KJS A;  4PTH A;  4LEK X;  4KM2 A;  4XRB A;  1DYH A;  1RA8 A;  3QLW A;  1OHJ A;  4H95 A;  4XT8 A;  3IA4 A;  4XT5 A;  4HOE A;  1BZF A;  2JYB A;  2O7P A;  3QL0 A;  3UM6 A;  4LAG X;  4ELH A;  2BLC A;  1CZ3 A;  3ZPG A;  1RA3 A;  3OAF A;  1DLR A;  4G95 A;  3TD8 A;  1RH3 A;  3DRC A;  3KFY A;  3S3V A;  3NXT A;  3SQY X;  1DRF A;  3JW5 A;  3FL8 A;  4KJJ A;  1RX1 A;  4G3M A;  2C2T A;  1RX5 A;  3TQA A;  4H97 A;  8DFR A;  2KGK A;  2BLA A;  3SRW X;  2ITH A;  1U70 A;  3TQ9 A;  3RO9 A;  3M08 A;  1DF7 A;  1D1G A;  3QLY A;  4P68 A;  5HT4 A;  1AOE A;  2W9T A;  3K45 A;  1DDS A;  3QFX A;  3EEL A;  3S9U A;  4H98 A;  1AO8 A;  1RX2 A;  4XT6 A;  2P4G A;  3IRM A;  2INQ A;  4M6K A;  1RX6 A;  5DFR A;  3FRA X;  5JG0 X;  3GYF A;  4GH8 A;  4Q67 A;  5HQY A;  1DIS A;  4FGG A;  3F91 A;  3JWC A;  4X5H A;  3NXR A;  4RGC A;  4DPH A;  5HF0 X;  4G8Z X;  5DXV A;  3SAI A;  1DR7 A;  3QLX A;  1DHJ A;  3QLS A;  4ELG A;  3R33 A;  3NTZ A;  4Q0E A;  2GD9 A;  4EJ1 A;  2HM9 A;  4KLX A;  1YHO A;  4KM0 A;  3FRD X;  1CD2 A;  3E0B A;  3TQ8 A;  3JSU A;  5CC9 A;  4M6J A;  1RB3 A;  3OCH A;  4KNE A;  4NX6 A;  5JA3 A;  2BLB A;  4M6L A;  4QLG A;  3QYO A;  4DDR A;  1LUD A;  1VJ3 A;  1IA1 A;  3NZB X;  3NZA X;  4CD2 A;  1DR6 A;  4PSS A;  1RX3 A;  1KMS A;  1DRE A;  1RA2 A;  1DDR A;  4XEC X;  1IA2 A;  3ROA A;  3JWF A;  1PDB A;  1DG7 A;  2OIP A;  3DFR A;  3SR5 X;  2ANO A;  3GHW A;  2D0K A;  2W9H A;  1DIU A;  5ECC A;  3RG9 A;  4XE6 X;  3F8Z A;  2W3M A;  3Q1H A;  1J3I A;  3CL9 A;  4I1N A;  4P3R A;  3SRU X;  2LF1 A;  4KY8 A;  4IXF X;  4M7V A;  1DYJ A;  1JUV A;  4DFR A;  5HF2 X;  1IA3 A;  3F0U X;  1RA1 A;  3FS6 A;  4M2X A;  4KFJ A;  3SH2 A;  1LY4 A;  4P3Q A;  1DRH A;  4X5J A; 
#chains in the Genus database with same CATH homology
 4DPD A;  3F0B X;  4KAK A;  3FQO A;  4KEB A;  5HSR A;  5EAJ A;  4EIZ A;  4HA7 A;  3NXO A;  4KJK A;  4EIL A;  5ECX A;  3INV A;  3F0X X;  4PTJ A;  1DG5 A;  3QLZ A;  3GHC A;  3EEM A;  3JWK A;  4HOF A;  4DP3 A;  3FY9 X;  4PSY A;  1DRA A;  1PD9 A;  3FY8 X;  5U27 A;  1M79 A;  2G6V A;  3L3R A;  3UM5 A;  1JOM A;  2CD2 A;  4PDJ A;  4FHB A;  3EIG A;  2W3B A;  4XT7 A;  1RE7 A;  3NXY A;  3NXV A;  1M78 A;  3K74 A;  3SA1 A;  1DR3 A;  2CIG A;  2DRC A;  1KLK A;  5HQZ A;  3QGT A;  4Q0D A;  4LAH X;  1RG7 A;  2H2Q A;  3IRN A;  4HA9 A;  3JW3 A;  2FZI A;  2ANQ A;  3FRB X;  3QL3 A;  1RX4 A;  3FYW X;  1S3V A;  1DLS A;  3IA5 A;  1HFP A;  5CCC A;  1KMV A;  3EEK A;  1RD7 A;  4KBN A;  1DR5 A;  1TDR A;  2QK8 A;  3FQV A;  1IA4 A;  2W9G A;  1DR4 A;  4QJZ D;  3GI2 A;  3SRR X;  1OHK A;  1MVS A;  3QLR A;  3ZPC A;  1M7A A;  4ELB A;  4X5G A;  3SA2 A;  3K2H A;  2B3Z A;  3QG2 A;  1RA9 A;  3FQC A;  4ECK A;  3NZ6 X;  1RF7 A;  3DL6 A;  1RX7 A;  4QI9 A;  2FZH A;  6DFR A;  3HJ3 A;  2W3W A;  2W9S A;  1J3K A;  4X5F A;  3FQ0 A;  1RX8 A;  3N0H A;  4H96 A;  3JWM A;  4XT4 A;  4I13 A;  5HVE A;  3EX8 A;  4ELE A;  5HT5 A;  4ELF A;  1S3U A;  4M7U A;  1HFR A;  3EEJ A;  3FRF X;  4FGH A;  1J3J A;  4OSG A;  3TQB A;  5HI6 A;  1HFQ A;  3NXX A;  2ZZA A;  5HVB A;  3D84 X;  2W3A A;  1U72 A;  3FYV X;  3NZ9 X;  3FL9 A;  3QYL A;  4QJC A;  5FDA A;  4IXG X;  4LAE X;  3F8Y A;  3IRO A;  4KD7 A;  1DG8 A;  3FQF A;  3GHV A;  3M09 A;  5HPB A;  4PST A;  1E26 A;  3SGY A;  1DYR A;  1RC4 A;  4X5I A;  3JTW A;  3KY8 A;  4KY4 A;  4QLE A;  3SRS X;  1DRB A;  3CSE A;  3NU0 A;  3HBB A;  2AZN A;  3SRQ X;  2OBC A;  1LY3 A;  1SEJ A;  4P66 A;  4HOG A;  4IXE D;  3CLB A;  5U26 A;  1DHF A;  3LG4 A;  1S3W A;  3DAT A;  3DG8 A;  2FZJ A;  3JVX A;  3DAU A;  3F0S X;  1RB2 A;  2XW7 A;  3VCO A;  3KGY A;  1JOL A;  4KL9 A;  1QZF A;  1VDR A;  5HSU A;  2C2S A;  2HXV A;  2D5N A;  3NRR A;  2HQP A;  3F0Q X;  1BOZ A;  3FRE X;  1U71 A;  3I3R A;  4QLF A;  4KJL A;  3KJR A;  3S7A A;  4KYA A;  3UM8 A;  4TU5 X;  3CD2 A;  1DR1 A;  3DGA A;  2L28 A;  2DHF A;  3IX9 A;  4NX7 A;  2W3V A;  1DHI A;  5E8Q A;  5HUI A;  1PD8 A;  1MVT A;  4OR7 A;  1DYI A;  1DR2 A;  3DL5 A;  3FQZ A;  4QHV A;  3F0V X;  3K47 A;  1AI9 A;  3NZC X;  3I8A X;  2BL9 A;  1S3Y A;  1ZDR A;  4EIG A;  7DFR A;  3NZD A;  3D80 A;  1DAJ A;  4Q6A A;  1RX9 A;  3KJS A;  4PTH A;  4LEK X;  4KM2 A;  4XRB A;  1DYH A;  1RA8 A;  3QLW A;  1OHJ A;  4H95 A;  4XT8 A;  3IA4 A;  4XT5 A;  4HOE A;  1BZF A;  2JYB A;  2O7P A;  3QL0 A;  3UM6 A;  4LAG X;  4ELH A;  2BLC A;  1CZ3 A;  3ZPG A;  1RA3 A;  3OAF A;  1DLR A;  4G95 A;  3TD8 A;  1RH3 A;  3DRC A;  3KFY A;  3S3V A;  3NXT A;  3SQY X;  1DRF A;  3JW5 A;  3FL8 A;  4KJJ A;  1RX1 A;  4G3M A;  2C2T A;  1RX5 A;  3TQA A;  4H97 A;  8DFR A;  2KGK A;  2BLA A;  3SRW X;  2ITH A;  1U70 A;  3TQ9 A;  3RO9 A;  3M08 A;  1DF7 A;  1D1G A;  3QLY A;  4P68 A;  5HT4 A;  1AOE A;  2W9T A;  3K45 A;  1DDS A;  3QFX A;  3EEL A;  3S9U A;  4H98 A;  1AO8 A;  1RX2 A;  4XT6 A;  2P4G A;  3IRM A;  2INQ A;  4M6K A;  1RX6 A;  5DFR A;  3FRA X;  5JG0 X;  3GYF A;  4GH8 A;  4Q67 A;  5HQY A;  1DIS A;  4FGG A;  3F91 A;  3JWC A;  4X5H A;  3NXR A;  4RGC A;  4DPH A;  5HF0 X;  4G8Z X;  5DXV A;  3SAI A;  1DR7 A;  3QLX A;  1DHJ A;  3QLS A;  4ELG A;  3R33 A;  3NTZ A;  4Q0E A;  2GD9 A;  4EJ1 A;  2HM9 A;  4KLX A;  1YHO A;  4KM0 A;  3FRD X;  1CD2 A;  3E0B A;  3TQ8 A;  3JSU A;  5CC9 A;  4M6J A;  1RB3 A;  3OCH A;  4KNE A;  4NX6 A;  5JA3 A;  2BLB A;  4M6L A;  4QLG A;  3QYO A;  4DDR A;  1LUD A;  1VJ3 A;  1IA1 A;  3NZB X;  3NZA X;  4CD2 A;  1DR6 A;  4PSS A;  1RX3 A;  1KMS A;  1DRE A;  1RA2 A;  1DDR A;  4XEC X;  1IA2 A;  3ROA A;  3JWF A;  1PDB A;  1DG7 A;  2OIP A;  3DFR A;  3SR5 X;  2ANO A;  3GHW A;  2D0K A;  2W9H A;  1DIU A;  5ECC A;  3RG9 A;  4XE6 X;  3F8Z A;  2W3M A;  3Q1H A;  1J3I A;  3CL9 A;  4I1N A;  4P3R A;  3SRU X;  2LF1 A;  4KY8 A;  4IXF X;  4M7V A;  1DYJ A;  1JUV A;  4DFR A;  5HF2 X;  1IA3 A;  3F0U X;  1RA1 A;  3FS6 A;  4M2X A;  4KFJ A;  3SH2 A;  1LY4 A;  4P3Q A;  1DRH A;  4X5J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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