4H96A

Candida albicans dihydrofolate reductase complexed with nadph and 5-{3-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methoxyphenyl]prop-1-yn-1-yl}-6-ethylpyrimidine-2,4-diamine (ucp1018)
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
189
structure length
189
Chain Sequence
PNVAIIVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHASSIESSLNLVSDVERVFIIGGAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFLKFPLESWTKQPKSELQKFVGDTVLEDDIKEGDFTYNYTLWTRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species.
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Candida albicans
molecule keywords Dihydrofolate Reductase
total genus 46
structure length 189
sequence length 189
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2012-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4h96A00
3KJSA 3D80A 3M08A 1LY4A 5CC9A 5JA3A 4M6LA 4DDRA 1DISA 1BOZA 3IROA 1D1GA 1S3WA 5CCCA 4LAGX 3UM8A 1DLSA 3SRSX 3FQOA 4PTHA 4G3MA 5U26A 2W3BA 3QYLA 4LEKX 1IA2A 2AZNA 1RB3A 1DHIA 3EEMA 1KMVA 4M7VA 5HF2X 2D5NA 3EELA 3NZBX 3S7AA 5HSRA 2LF1A 1M78A 2G6VA 5HF0X 3FQCA 3F0VX 1RA8A 3FRBX 2W9SA 6DFRA 3SA1A 4KYAA 3GYFA 4XT5A 1DR5A 4EILA 4PSYA 3FY8X 1RF7A 5EAJA 1HFQA 3NXXA 4LAHX 2FZHA 3DL5A 1CZ3A 4QLEA 4HOFA 3EEJA 3KFYA 2W3WA 1CD2A 4ELFA 4DP3A 4Q0EA 3SAIA 1RE7A 4KD7A 4NX6A 3FQVA 3FYVX 3S3VA 4IXGX 4Q67A 4KY4A 3TQBA 4KJLA 3NU0A 2W9HA 3S9UA 4DPDA 3IA4A 4I1NA 3OCHA 2OBCA 4HA7A 4HOGA 3FRFX 3EEKA 2FZIA 5HPBA 3HBBA 1YHOA 3N0HA 3GHVA 1S3VA 4HOEA 3DATA 4EIZA 5E8QA 4DPHA 3DFRA 4FHBA 4KY8A 3ZPCA 4KFJA 3IRNA 3NRRA 3NZAX 1M7AA 3SRRX 1RA9A 1SEJA 3FY9X 3IA5A 1PD8A 1RA1A 5DXVA 3NZCX 1DDRA 5HSUA 3JVXA 1RA2A 1DLRA 3JWCA 3CSEA 4OR7A 1PDBA 3I3RA 2DHFA 3M09A 4IXED 1DREA 4LAEX 3JW3A 1RX9A 4CD2A 3SRQX 4FGHA 5HT4A 3SH2A 4KLXA 3RO9A 2C2SA 3FQ0A 2FZJA 1DR4A 3DL6A 4RGCA 4KL9A 1DF7A 2KGKA 4EIGA 3TQ9A 1JOMA 3NZ9X 1AOEA 1HFRA 1DHFA 1LY3A 4Q6AA 3F0QX 3GI2A 4G8ZX 3FRDX 1DRBA 3F91A 1S3YA 1DRHA 5HQZA 3QLSA 3QLZA 4KNEA 2HXVA 4M7UA 5HQYA 1LUDA 4EJ1A 1J3KA 2W3AA 4XT7A 1RX3A 1AI9A 5ECCA 1MVTA 4KBNA 3F0XX 3E0BA 2OIPA 4OSGA 2GD9A 5DFRA 4M2XA 1RG7A 4PSTA 4PDJA 1RX5A 1RA3A 3SRUX 3QLYA 3QYOA 4X5IA 1RX1A 5U27A 1DHJA 1U71A 2C2TA 7DFRA 1OHKA 2DRCA 1RX6A 3JSUA 2CIGA 4QJZD 1DYRA 4XECX 3TQ8A 4QLFA 3CD2A 4PSSA 4XT6A 4TU5X 1JUVA 3JWMA 1DG8A 3UM6A 3I8AX 1DRAA 2ANOA 2W3MA 4KM0A 3IRMA 2JYBA 1RX7A 2O7PA 4ECKA 4KJKA 2CD2A 2D0KA 1VDRA 2INQA 4XRBA 4G95A 4XT8A 1DIUA 1DG7A 3R33A 3ZPGA 4PTJA 3DGAA 3QLRA 1U70A 3DAUA 1RD7A 3QLXA 4NX7A 1KLKA 1DR1A 3NTZA 1QZFA 2W9GA 3GHWA 4KEBA 4IXFX 4X5GA 3DG8A 3SQYX 3EX8A 8DFRA 1IA4A 1ZDRA 1AO8A 1RX2A 3INVA 3NXTA 3NXVA 3JW5A 3JWKA 1J3IA 1DR7A 3IX9A 3K74A 4KAKA 1RB2A 3KGYA 1DDSA 4QJCA 3F8ZA 1IA1A 3GHCA 5HVEA 3RG9A 4XT4A 2L28A 4I13A 4DFRA 3NXRA 3UM5A 3ROAA 3QFXA 3QGTA 5ECXA 2W3VA 2ZZAA 4HA9A 3FL9A 4P3QA 3F0SX 1J3JA 3NZ6X 1DRFA 1TDRA 1U72A 3VCOA 3FRAX 3QLWA 5HUIA 3FQZA 3Q1HA 3CLBA 2BLAA 2BLBA 4X5JA 1DYJA 4P3RA 2P4GA 3QL3A 1RC4A 1HFPA 4P68A 1RX8A 2XW7A 4XE6X 4ELGA 3FS6A 3FQFA 3FREX 4P66A 3EIGA 3QG2A 2HQPA 3HJ3A 4Q0DA 1BZFA 2B3ZA 1KMSA 4X5HA 3FYWX 2ITHA 1DAJA 4M6KA 4KJJA 4H98A 1E26A 2BLCA 1DYIA 4H96A 3TQAA 5HVBA 3SR5X 3F0UX 3JWFA 3QL0A 4QLGA 1DG5A 3SGYA 4FGGA 1RH3A 1JOLA 3OAFA 1DR6A 3JTWA 4X5FA 1DR3A 3K2HA 4QHVA 1OHJA 1PD9A 4KM2A 2W9TA 3F8YA 5HI6A 2QK8A 1DR2A 3SA2A 4M6JA 1MVSA 4GH8A 3K45A 3DRCA 1S3UA 3TD8A 1IA3A 4QI9A 2HM9A 3LG4A 2ANQA 4ELEA 4ELBA 3L3RA 3NZDA 1VJ3A 5JG0X 2BL9A 2H2QA 4H95A 3KY8A 1RX4A 3FL8A 1DYHA 3NXOA 1M79A 3SRWX 3F0BX 3NXYA 4ELHA 3CL9A 5FDAA 5HT5A 4H97A 3KJRA 3K47A 3D84X
chains in the Genus database with same CATH superfamily
3KJSA 3D80A 3M08A 1LY4A 5CC9A 5JA3A 4M6LA 4DDRA 1DISA 1BOZA 3IROA 1D1GA 1S3WA 5CCCA 4LAGX 3UM8A 1DLSA 3SRSX 3FQOA 4PTHA 4G3MA 5U26A 2W3BA 3QYLA 4LEKX 1IA2A 2AZNA 1RB3A 1DHIA 3EEMA 1KMVA 4M7VA 5HF2X 2D5NA 3EELA 3NZBX 3S7AA 5HSRA 2LF1A 1M78A 2G6VA 5HF0X 3FQCA 3F0VX 1RA8A 3FRBX 2W9SA 6DFRA 3SA1A 4KYAA 3GYFA 4XT5A 1DR5A 4EILA 4PSYA 3FY8X 1RF7A 5EAJA 1HFQA 3NXXA 4LAHX 2FZHA 3DL5A 1CZ3A 4QLEA 4HOFA 3EEJA 3KFYA 2W3WA 1CD2A 4ELFA 4DP3A 4Q0EA 3SAIA 1RE7A 4KD7A 4NX6A 3FQVA 3FYVX 3S3VA 4IXGX 4Q67A 4KY4A 3TQBA 4KJLA 3NU0A 2W9HA 3S9UA 4DPDA 3IA4A 4I1NA 3OCHA 2OBCA 4HA7A 4HOGA 3FRFX 3EEKA 2FZIA 5HPBA 3HBBA 1YHOA 3N0HA 3GHVA 1S3VA 4HOEA 3DATA 4EIZA 5E8QA 4DPHA 3DFRA 4FHBA 4KY8A 3ZPCA 4KFJA 3IRNA 3NRRA 3NZAX 1M7AA 3SRRX 1RA9A 1SEJA 3FY9X 3IA5A 1PD8A 1RA1A 5DXVA 3NZCX 1DDRA 5HSUA 3JVXA 1RA2A 1DLRA 3JWCA 3CSEA 4OR7A 1PDBA 3I3RA 2DHFA 3M09A 4IXED 1DREA 4LAEX 3JW3A 1RX9A 4CD2A 3SRQX 4FGHA 5HT4A 3SH2A 4KLXA 3RO9A 2C2SA 3FQ0A 2FZJA 1DR4A 3DL6A 4RGCA 4KL9A 1DF7A 2KGKA 4EIGA 3TQ9A 1JOMA 3NZ9X 1AOEA 1HFRA 1DHFA 1LY3A 4Q6AA 3F0QX 3GI2A 4G8ZX 3FRDX 1DRBA 3F91A 1S3YA 1DRHA 5HQZA 3QLSA 3QLZA 4KNEA 2HXVA 4M7UA 5HQYA 1LUDA 4EJ1A 1J3KA 2W3AA 4XT7A 1RX3A 1AI9A 5ECCA 1MVTA 4KBNA 3F0XX 3E0BA 2OIPA 4OSGA 2GD9A 5DFRA 4M2XA 1RG7A 4PSTA 4PDJA 1RX5A 1RA3A 3SRUX 3QLYA 3QYOA 4X5IA 1RX1A 5U27A 1DHJA 1U71A 2C2TA 7DFRA 1OHKA 2DRCA 1RX6A 3JSUA 2CIGA 4QJZD 1DYRA 4XECX 3TQ8A 4QLFA 3CD2A 4PSSA 4XT6A 4TU5X 1JUVA 3JWMA 1DG8A 3UM6A 3I8AX 1DRAA 2ANOA 2W3MA 4KM0A 3IRMA 2JYBA 1RX7A 2O7PA 4ECKA 4KJKA 2CD2A 2D0KA 1VDRA 2INQA 4XRBA 4G95A 4XT8A 1DIUA 1DG7A 3R33A 3ZPGA 4PTJA 3DGAA 3QLRA 1U70A 3DAUA 1RD7A 3QLXA 4NX7A 1KLKA 1DR1A 3NTZA 1QZFA 2W9GA 3GHWA 4KEBA 4IXFX 4X5GA 3DG8A 3SQYX 3EX8A 8DFRA 1IA4A 1ZDRA 1AO8A 1RX2A 3INVA 3NXTA 3NXVA 3JW5A 3JWKA 1J3IA 1DR7A 3IX9A 3K74A 4KAKA 1RB2A 3KGYA 1DDSA 4QJCA 3F8ZA 1IA1A 3GHCA 5HVEA 3RG9A 4XT4A 2L28A 4I13A 4DFRA 3NXRA 3UM5A 3ROAA 3QFXA 3QGTA 5ECXA 2W3VA 2ZZAA 4HA9A 3FL9A 4P3QA 3F0SX 1J3JA 3NZ6X 1DRFA 1TDRA 1U72A 3VCOA 3FRAX 3QLWA 5HUIA 3FQZA 3Q1HA 3CLBA 2BLAA 2BLBA 4X5JA 1DYJA 4P3RA 2P4GA 3QL3A 1RC4A 1HFPA 4P68A 1RX8A 2XW7A 4XE6X 4ELGA 3FS6A 3FQFA 3FREX 4P66A 3EIGA 3QG2A 2HQPA 3HJ3A 4Q0DA 1BZFA 2B3ZA 1KMSA 4X5HA 3FYWX 2ITHA 1DAJA 4M6KA 4KJJA 4H98A 1E26A 2BLCA 1DYIA 4H96A 3TQAA 5HVBA 3SR5X 3F0UX 3JWFA 3QL0A 4QLGA 1DG5A 3SGYA 4FGGA 1RH3A 1JOLA 3OAFA 1DR6A 3JTWA 4X5FA 1DR3A 3K2HA 4QHVA 1OHJA 1PD9A 4KM2A 2W9TA 3F8YA 5HI6A 2QK8A 1DR2A 3SA2A 4M6JA 1MVSA 4GH8A 3K45A 3DRCA 1S3UA 3TD8A 1IA3A 4QI9A 2HM9A 3LG4A 2ANQA 4ELEA 4ELBA 3L3RA 3NZDA 1VJ3A 5JG0X 2BL9A 2H2QA 4H95A 3KY8A 1RX4A 3FL8A 1DYHA 3NXOA 1M79A 3SRWX 3F0BX 3NXYA 4ELHA 3CL9A 5FDAA 5HT5A 4H97A 3KJRA 3K47A 3D84X
chains in the Genus database with same CATH topology
3KJSA 3D80A 3M08A 1LY4A 5CC9A 5JA3A 4M6LA 4DDRA 1DISA 1BOZA 3IROA 1D1GA 1S3WA 5CCCA 4LAGX 3UM8A 1DLSA 3SRSX 3FQOA 4PTHA 4G3MA 5U26A 2W3BA 3QYLA 4LEKX 1IA2A 2AZNA 1RB3A 1DHIA 3EEMA 1KMVA 4M7VA 5HF2X 2D5NA 3EELA 3NZBX 3S7AA 5HSRA 2LF1A 1M78A 2G6VA 5HF0X 3FQCA 3F0VX 1RA8A 3FRBX 2W9SA 6DFRA 3SA1A 4KYAA 3GYFA 4XT5A 1DR5A 4EILA 4PSYA 3FY8X 1RF7A 5EAJA 1HFQA 3NXXA 4LAHX 2FZHA 3DL5A 1CZ3A 4QLEA 4HOFA 3EEJA 3KFYA 2W3WA 1CD2A 4ELFA 4DP3A 4Q0EA 3SAIA 1RE7A 4KD7A 4NX6A 3FQVA 3FYVX 3S3VA 4IXGX 4Q67A 4KY4A 3TQBA 4KJLA 3NU0A 2W9HA 3S9UA 4DPDA 3IA4A 4I1NA 3OCHA 2OBCA 4HA7A 4HOGA 3FRFX 3EEKA 2FZIA 5HPBA 3HBBA 1YHOA 3N0HA 3GHVA 1S3VA 4HOEA 3DATA 4EIZA 5E8QA 4DPHA 3DFRA 4FHBA 4KY8A 3ZPCA 4KFJA 3IRNA 3NRRA 3NZAX 1M7AA 3SRRX 1RA9A 1SEJA 3FY9X 3IA5A 1PD8A 1RA1A 5DXVA 3NZCX 1DDRA 5HSUA 3JVXA 1RA2A 1DLRA 3JWCA 3CSEA 4OR7A 1PDBA 3I3RA 2DHFA 3M09A 4IXED 1DREA 4LAEX 3JW3A 1RX9A 4CD2A 3SRQX 4FGHA 5HT4A 3SH2A 4KLXA 3RO9A 2C2SA 3FQ0A 2FZJA 1DR4A 3DL6A 4RGCA 4KL9A 1DF7A 2KGKA 4EIGA 3TQ9A 1JOMA 3NZ9X 1AOEA 1HFRA 1DHFA 1LY3A 4Q6AA 3F0QX 3GI2A 4G8ZX 3FRDX 1DRBA 3F91A 1S3YA 1DRHA 5HQZA 3QLSA 3QLZA 4KNEA 2HXVA 4M7UA 5HQYA 1LUDA 4EJ1A 1J3KA 2W3AA 4XT7A 1RX3A 1AI9A 5ECCA 1MVTA 4KBNA 3F0XX 3E0BA 2OIPA 4OSGA 2GD9A 5DFRA 4M2XA 1RG7A 4PSTA 4PDJA 1RX5A 1RA3A 3SRUX 3QLYA 3QYOA 4X5IA 1RX1A 5U27A 1DHJA 1U71A 2C2TA 7DFRA 1OHKA 2DRCA 1RX6A 3JSUA 2CIGA 4QJZD 1DYRA 4XECX 3TQ8A 4QLFA 3CD2A 4PSSA 4XT6A 4TU5X 1JUVA 3JWMA 1DG8A 3UM6A 3I8AX 1DRAA 2ANOA 2W3MA 4KM0A 3IRMA 2JYBA 1RX7A 2O7PA 4ECKA 4KJKA 2CD2A 2D0KA 1VDRA 2INQA 4XRBA 4G95A 4XT8A 1DIUA 1DG7A 3R33A 3ZPGA 4PTJA 3DGAA 3QLRA 1U70A 3DAUA 1RD7A 3QLXA 4NX7A 1KLKA 1DR1A 3NTZA 1QZFA 2W9GA 3GHWA 4KEBA 4IXFX 4X5GA 3DG8A 3SQYX 3EX8A 8DFRA 1IA4A 1ZDRA 1AO8A 1RX2A 3INVA 3NXTA 3NXVA 3JW5A 3JWKA 1J3IA 1DR7A 3IX9A 3K74A 4KAKA 1RB2A 3KGYA 1DDSA 4QJCA 3F8ZA 1IA1A 3GHCA 5HVEA 3RG9A 4XT4A 2L28A 4I13A 4DFRA 3NXRA 3UM5A 3ROAA 3QFXA 3QGTA 5ECXA 2W3VA 2ZZAA 4HA9A 3FL9A 4P3QA 3F0SX 1J3JA 3NZ6X 1DRFA 1TDRA 1U72A 3VCOA 3FRAX 3QLWA 5HUIA 3FQZA 3Q1HA 3CLBA 2BLAA 2BLBA 4X5JA 1DYJA 4P3RA 2P4GA 3QL3A 1RC4A 1HFPA 4P68A 1RX8A 2XW7A 4XE6X 4ELGA 3FS6A 3FQFA 3FREX 4P66A 3EIGA 3QG2A 2HQPA 3HJ3A 4Q0DA 1BZFA 2B3ZA 1KMSA 4X5HA 3FYWX 2ITHA 1DAJA 4M6KA 4KJJA 4H98A 1E26A 2BLCA 1DYIA 4H96A 3TQAA 5HVBA 3SR5X 3F0UX 3JWFA 3QL0A 4QLGA 1DG5A 3SGYA 4FGGA 1RH3A 1JOLA 3OAFA 1DR6A 3JTWA 4X5FA 1DR3A 3K2HA 4QHVA 1OHJA 1PD9A 4KM2A 2W9TA 3F8YA 5HI6A 2QK8A 1DR2A 3SA2A 4M6JA 1MVSA 4GH8A 3K45A 3DRCA 1S3UA 3TD8A 1IA3A 4QI9A 2HM9A 3LG4A 2ANQA 4ELEA 4ELBA 3L3RA 3NZDA 1VJ3A 5JG0X 2BL9A 2H2QA 4H95A 3KY8A 1RX4A 3FL8A 1DYHA 3NXOA 1M79A 3SRWX 3F0BX 3NXYA 4ELHA 3CL9A 5FDAA 5HT5A 4H97A 3KJRA 3K47A 3D84X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KJS A;  3D80 A;  3M08 A;  1LY4 A;  5CC9 A;  5JA3 A;  4M6L A;  4DDR A;  1DIS A;  1BOZ A;  3IRO A;  1D1G A;  1S3W A;  5CCC A;  4LAG X;  3UM8 A;  1DLS A;  3SRS X;  3FQO A;  4PTH A;  4G3M A;  5U26 A;  2W3B A;  3QYL A;  4LEK X;  1IA2 A;  2AZN A;  1RB3 A;  1DHI A;  3EEM A;  1KMV A;  4M7V A;  5HF2 X;  2D5N A;  3EEL A;  3NZB X;  3S7A A;  5HSR A;  2LF1 A;  1M78 A;  2G6V A;  5HF0 X;  3FQC A;  3F0V X;  1RA8 A;  3FRB X;  2W9S A;  6DFR A;  3SA1 A;  4KYA A;  3GYF A;  4XT5 A;  1DR5 A;  4EIL A;  4PSY A;  3FY8 X;  1RF7 A;  5EAJ A;  1HFQ A;  3NXX A;  4LAH X;  2FZH A;  3DL5 A;  1CZ3 A;  4QLE A;  4HOF A;  3EEJ A;  3KFY A;  2W3W A;  1CD2 A;  4ELF A;  4DP3 A;  4Q0E A;  3SAI A;  1RE7 A;  4KD7 A;  4NX6 A;  3FQV A;  3FYV X;  3S3V A;  4IXG X;  4Q67 A;  4KY4 A;  3TQB A;  4KJL A;  3NU0 A;  2W9H A;  3S9U A;  4DPD A;  3IA4 A;  4I1N A;  3OCH A;  2OBC A;  4HA7 A;  4HOG A;  3FRF X;  3EEK A;  2FZI A;  5HPB A;  3HBB A;  1YHO A;  3N0H A;  3GHV A;  1S3V A;  4HOE A;  3DAT A;  4EIZ A;  5E8Q A;  4DPH A;  3DFR A;  4FHB A;  4KY8 A;  3ZPC A;  4KFJ A;  3IRN A;  3NRR A;  3NZA X;  1M7A A;  3SRR X;  1RA9 A;  1SEJ A;  3FY9 X;  3IA5 A;  1PD8 A;  1RA1 A;  5DXV A;  3NZC X;  1DDR A;  5HSU A;  3JVX A;  1RA2 A;  1DLR A;  3JWC A;  3CSE A;  4OR7 A;  1PDB A;  3I3R A;  2DHF A;  3M09 A;  4IXE D;  1DRE A;  4LAE X;  3JW3 A;  1RX9 A;  4CD2 A;  3SRQ X;  4FGH A;  5HT4 A;  3SH2 A;  4KLX A;  3RO9 A;  2C2S A;  3FQ0 A;  2FZJ A;  1DR4 A;  3DL6 A;  4RGC A;  4KL9 A;  1DF7 A;  2KGK A;  4EIG A;  3TQ9 A;  1JOM A;  3NZ9 X;  1AOE A;  1HFR A;  1DHF A;  1LY3 A;  4Q6A A;  3F0Q X;  3GI2 A;  4G8Z X;  3FRD X;  1DRB A;  3F91 A;  1S3Y A;  1DRH A;  5HQZ A;  3QLS A;  3QLZ A;  4KNE A;  2HXV A;  4M7U A;  5HQY A;  1LUD A;  4EJ1 A;  1J3K A;  2W3A A;  4XT7 A;  1RX3 A;  1AI9 A;  5ECC A;  1MVT A;  4KBN A;  3F0X X;  3E0B A;  2OIP A;  4OSG A;  2GD9 A;  5DFR A;  4M2X A;  1RG7 A;  4PST A;  4PDJ A;  1RX5 A;  1RA3 A;  3SRU X;  3QLY A;  3QYO A;  4X5I A;  1RX1 A;  5U27 A;  1DHJ A;  1U71 A;  2C2T A;  7DFR A;  1OHK A;  2DRC A;  1RX6 A;  3JSU A;  2CIG A;  4QJZ D;  1DYR A;  4XEC X;  3TQ8 A;  4QLF A;  3CD2 A;  4PSS A;  4XT6 A;  4TU5 X;  1JUV A;  3JWM A;  1DG8 A;  3UM6 A;  3I8A X;  1DRA A;  2ANO A;  2W3M A;  4KM0 A;  3IRM A;  2JYB A;  1RX7 A;  2O7P A;  4ECK A;  4KJK A;  2CD2 A;  2D0K A;  1VDR A;  2INQ A;  4XRB A;  4G95 A;  4XT8 A;  1DIU A;  1DG7 A;  3R33 A;  3ZPG A;  4PTJ A;  3DGA A;  3QLR A;  1U70 A;  3DAU A;  1RD7 A;  3QLX A;  4NX7 A;  1KLK A;  1DR1 A;  3NTZ A;  1QZF A;  2W9G A;  3GHW A;  4KEB A;  4IXF X;  4X5G A;  3DG8 A;  3SQY X;  3EX8 A;  8DFR A;  1IA4 A;  1ZDR A;  1AO8 A;  1RX2 A;  3INV A;  3NXT A;  3NXV A;  3JW5 A;  3JWK A;  1J3I A;  1DR7 A;  3IX9 A;  3K74 A;  4KAK A;  1RB2 A;  3KGY A;  1DDS A;  4QJC A;  3F8Z A;  1IA1 A;  3GHC A;  5HVE A;  3RG9 A;  4XT4 A;  2L28 A;  4I13 A;  4DFR A;  3NXR A;  3UM5 A;  3ROA A;  3QFX A;  3QGT A;  5ECX A;  2W3V A;  2ZZA A;  4HA9 A;  3FL9 A;  4P3Q A;  3F0S X;  1J3J A;  3NZ6 X;  1DRF A;  1TDR A;  1U72 A;  3VCO A;  3FRA X;  3QLW A;  5HUI A;  3FQZ A;  3Q1H A;  3CLB A;  2BLA A;  2BLB A;  4X5J A;  1DYJ A;  4P3R A;  2P4G A;  3QL3 A;  1RC4 A;  1HFP A;  4P68 A;  1RX8 A;  2XW7 A;  4XE6 X;  4ELG A;  3FS6 A;  3FQF A;  3FRE X;  4P66 A;  3EIG A;  3QG2 A;  2HQP A;  3HJ3 A;  4Q0D A;  1BZF A;  2B3Z A;  1KMS A;  4X5H A;  3FYW X;  2ITH A;  1DAJ A;  4M6K A;  4KJJ A;  4H98 A;  1E26 A;  2BLC A;  1DYI A;  4H96 A;  3TQA A;  5HVB A;  3SR5 X;  3F0U X;  3JWF A;  3QL0 A;  4QLG A;  1DG5 A;  3SGY A;  4FGG A;  1RH3 A;  1JOL A;  3OAF A;  1DR6 A;  3JTW A;  4X5F A;  1DR3 A;  3K2H A;  4QHV A;  1OHJ A;  1PD9 A;  4KM2 A;  2W9T A;  3F8Y A;  5HI6 A;  2QK8 A;  1DR2 A;  3SA2 A;  4M6J A;  1MVS A;  4GH8 A;  3K45 A;  3DRC A;  1S3U A;  3TD8 A;  1IA3 A;  4QI9 A;  2HM9 A;  3LG4 A;  2ANQ A;  4ELE A;  4ELB A;  3L3R A;  3NZD A;  1VJ3 A;  5JG0 X;  2BL9 A;  2H2Q A;  4H95 A;  3KY8 A;  1RX4 A;  3FL8 A;  1DYH A;  3NXO A;  1M79 A;  3SRW X;  3F0B X;  3NXY A;  4ELH A;  3CL9 A;  5FDA A;  5HT5 A;  4H97 A;  3KJR A;  3K47 A;  3D84 X; 
#chains in the Genus database with same CATH topology
 3KJS A;  3D80 A;  3M08 A;  1LY4 A;  5CC9 A;  5JA3 A;  4M6L A;  4DDR A;  1DIS A;  1BOZ A;  3IRO A;  1D1G A;  1S3W A;  5CCC A;  4LAG X;  3UM8 A;  1DLS A;  3SRS X;  3FQO A;  4PTH A;  4G3M A;  5U26 A;  2W3B A;  3QYL A;  4LEK X;  1IA2 A;  2AZN A;  1RB3 A;  1DHI A;  3EEM A;  1KMV A;  4M7V A;  5HF2 X;  2D5N A;  3EEL A;  3NZB X;  3S7A A;  5HSR A;  2LF1 A;  1M78 A;  2G6V A;  5HF0 X;  3FQC A;  3F0V X;  1RA8 A;  3FRB X;  2W9S A;  6DFR A;  3SA1 A;  4KYA A;  3GYF A;  4XT5 A;  1DR5 A;  4EIL A;  4PSY A;  3FY8 X;  1RF7 A;  5EAJ A;  1HFQ A;  3NXX A;  4LAH X;  2FZH A;  3DL5 A;  1CZ3 A;  4QLE A;  4HOF A;  3EEJ A;  3KFY A;  2W3W A;  1CD2 A;  4ELF A;  4DP3 A;  4Q0E A;  3SAI A;  1RE7 A;  4KD7 A;  4NX6 A;  3FQV A;  3FYV X;  3S3V A;  4IXG X;  4Q67 A;  4KY4 A;  3TQB A;  4KJL A;  3NU0 A;  2W9H A;  3S9U A;  4DPD A;  3IA4 A;  4I1N A;  3OCH A;  2OBC A;  4HA7 A;  4HOG A;  3FRF X;  3EEK A;  2FZI A;  5HPB A;  3HBB A;  1YHO A;  3N0H A;  3GHV A;  1S3V A;  4HOE A;  3DAT A;  4EIZ A;  5E8Q A;  4DPH A;  3DFR A;  4FHB A;  4KY8 A;  3ZPC A;  4KFJ A;  3IRN A;  3NRR A;  3NZA X;  1M7A A;  3SRR X;  1RA9 A;  1SEJ A;  3FY9 X;  3IA5 A;  1PD8 A;  1RA1 A;  5DXV A;  3NZC X;  1DDR A;  5HSU A;  3JVX A;  1RA2 A;  1DLR A;  3JWC A;  3CSE A;  4OR7 A;  1PDB A;  3I3R A;  2DHF A;  3M09 A;  4IXE D;  1DRE A;  4LAE X;  3JW3 A;  1RX9 A;  4CD2 A;  3SRQ X;  4FGH A;  5HT4 A;  3SH2 A;  4KLX A;  3RO9 A;  2C2S A;  3FQ0 A;  2FZJ A;  1DR4 A;  3DL6 A;  4RGC A;  4KL9 A;  1DF7 A;  2KGK A;  4EIG A;  3TQ9 A;  1JOM A;  3NZ9 X;  1AOE A;  1HFR A;  1DHF A;  1LY3 A;  4Q6A A;  3F0Q X;  3GI2 A;  4G8Z X;  3FRD X;  1DRB A;  3F91 A;  1S3Y A;  1DRH A;  5HQZ A;  3QLS A;  3QLZ A;  4KNE A;  2HXV A;  4M7U A;  5HQY A;  1LUD A;  4EJ1 A;  1J3K A;  2W3A A;  4XT7 A;  1RX3 A;  1AI9 A;  5ECC A;  1MVT A;  4KBN A;  3F0X X;  3E0B A;  2OIP A;  4OSG A;  2GD9 A;  5DFR A;  4M2X A;  1RG7 A;  4PST A;  4PDJ A;  1RX5 A;  1RA3 A;  3SRU X;  3QLY A;  3QYO A;  4X5I A;  1RX1 A;  5U27 A;  1DHJ A;  1U71 A;  2C2T A;  7DFR A;  1OHK A;  2DRC A;  1RX6 A;  3JSU A;  2CIG A;  4QJZ D;  1DYR A;  4XEC X;  3TQ8 A;  4QLF A;  3CD2 A;  4PSS A;  4XT6 A;  4TU5 X;  1JUV A;  3JWM A;  1DG8 A;  3UM6 A;  3I8A X;  1DRA A;  2ANO A;  2W3M A;  4KM0 A;  3IRM A;  2JYB A;  1RX7 A;  2O7P A;  4ECK A;  4KJK A;  2CD2 A;  2D0K A;  1VDR A;  2INQ A;  4XRB A;  4G95 A;  4XT8 A;  1DIU A;  1DG7 A;  3R33 A;  3ZPG A;  4PTJ A;  3DGA A;  3QLR A;  1U70 A;  3DAU A;  1RD7 A;  3QLX A;  4NX7 A;  1KLK A;  1DR1 A;  3NTZ A;  1QZF A;  2W9G A;  3GHW A;  4KEB A;  4IXF X;  4X5G A;  3DG8 A;  3SQY X;  3EX8 A;  8DFR A;  1IA4 A;  1ZDR A;  1AO8 A;  1RX2 A;  3INV A;  3NXT A;  3NXV A;  3JW5 A;  3JWK A;  1J3I A;  1DR7 A;  3IX9 A;  3K74 A;  4KAK A;  1RB2 A;  3KGY A;  1DDS A;  4QJC A;  3F8Z A;  1IA1 A;  3GHC A;  5HVE A;  3RG9 A;  4XT4 A;  2L28 A;  4I13 A;  4DFR A;  3NXR A;  3UM5 A;  3ROA A;  3QFX A;  3QGT A;  5ECX A;  2W3V A;  2ZZA A;  4HA9 A;  3FL9 A;  4P3Q A;  3F0S X;  1J3J A;  3NZ6 X;  1DRF A;  1TDR A;  1U72 A;  3VCO A;  3FRA X;  3QLW A;  5HUI A;  3FQZ A;  3Q1H A;  3CLB A;  2BLA A;  2BLB A;  4X5J A;  1DYJ A;  4P3R A;  2P4G A;  3QL3 A;  1RC4 A;  1HFP A;  4P68 A;  1RX8 A;  2XW7 A;  4XE6 X;  4ELG A;  3FS6 A;  3FQF A;  3FRE X;  4P66 A;  3EIG A;  3QG2 A;  2HQP A;  3HJ3 A;  4Q0D A;  1BZF A;  2B3Z A;  1KMS A;  4X5H A;  3FYW X;  2ITH A;  1DAJ A;  4M6K A;  4KJJ A;  4H98 A;  1E26 A;  2BLC A;  1DYI A;  4H96 A;  3TQA A;  5HVB A;  3SR5 X;  3F0U X;  3JWF A;  3QL0 A;  4QLG A;  1DG5 A;  3SGY A;  4FGG A;  1RH3 A;  1JOL A;  3OAF A;  1DR6 A;  3JTW A;  4X5F A;  1DR3 A;  3K2H A;  4QHV A;  1OHJ A;  1PD9 A;  4KM2 A;  2W9T A;  3F8Y A;  5HI6 A;  2QK8 A;  1DR2 A;  3SA2 A;  4M6J A;  1MVS A;  4GH8 A;  3K45 A;  3DRC A;  1S3U A;  3TD8 A;  1IA3 A;  4QI9 A;  2HM9 A;  3LG4 A;  2ANQ A;  4ELE A;  4ELB A;  3L3R A;  3NZD A;  1VJ3 A;  5JG0 X;  2BL9 A;  2H2Q A;  4H95 A;  3KY8 A;  1RX4 A;  3FL8 A;  1DYH A;  3NXO A;  1M79 A;  3SRW X;  3F0B X;  3NXY A;  4ELH A;  3CL9 A;  5FDA A;  5HT5 A;  4H97 A;  3KJR A;  3K47 A;  3D84 X; 
#chains in the Genus database with same CATH homology
 3KJS A;  3D80 A;  3M08 A;  1LY4 A;  5CC9 A;  5JA3 A;  4M6L A;  4DDR A;  1DIS A;  1BOZ A;  3IRO A;  1D1G A;  1S3W A;  5CCC A;  4LAG X;  3UM8 A;  1DLS A;  3SRS X;  3FQO A;  4PTH A;  4G3M A;  5U26 A;  2W3B A;  3QYL A;  4LEK X;  1IA2 A;  2AZN A;  1RB3 A;  1DHI A;  3EEM A;  1KMV A;  4M7V A;  5HF2 X;  2D5N A;  3EEL A;  3NZB X;  3S7A A;  5HSR A;  2LF1 A;  1M78 A;  2G6V A;  5HF0 X;  3FQC A;  3F0V X;  1RA8 A;  3FRB X;  2W9S A;  6DFR A;  3SA1 A;  4KYA A;  3GYF A;  4XT5 A;  1DR5 A;  4EIL A;  4PSY A;  3FY8 X;  1RF7 A;  5EAJ A;  1HFQ A;  3NXX A;  4LAH X;  2FZH A;  3DL5 A;  1CZ3 A;  4QLE A;  4HOF A;  3EEJ A;  3KFY A;  2W3W A;  1CD2 A;  4ELF A;  4DP3 A;  4Q0E A;  3SAI A;  1RE7 A;  4KD7 A;  4NX6 A;  3FQV A;  3FYV X;  3S3V A;  4IXG X;  4Q67 A;  4KY4 A;  3TQB A;  4KJL A;  3NU0 A;  2W9H A;  3S9U A;  4DPD A;  3IA4 A;  4I1N A;  3OCH A;  2OBC A;  4HA7 A;  4HOG A;  3FRF X;  3EEK A;  2FZI A;  5HPB A;  3HBB A;  1YHO A;  3N0H A;  3GHV A;  1S3V A;  4HOE A;  3DAT A;  4EIZ A;  5E8Q A;  4DPH A;  3DFR A;  4FHB A;  4KY8 A;  3ZPC A;  4KFJ A;  3IRN A;  3NRR A;  3NZA X;  1M7A A;  3SRR X;  1RA9 A;  1SEJ A;  3FY9 X;  3IA5 A;  1PD8 A;  1RA1 A;  5DXV A;  3NZC X;  1DDR A;  5HSU A;  3JVX A;  1RA2 A;  1DLR A;  3JWC A;  3CSE A;  4OR7 A;  1PDB A;  3I3R A;  2DHF A;  3M09 A;  4IXE D;  1DRE A;  4LAE X;  3JW3 A;  1RX9 A;  4CD2 A;  3SRQ X;  4FGH A;  5HT4 A;  3SH2 A;  4KLX A;  3RO9 A;  2C2S A;  3FQ0 A;  2FZJ A;  1DR4 A;  3DL6 A;  4RGC A;  4KL9 A;  1DF7 A;  2KGK A;  4EIG A;  3TQ9 A;  1JOM A;  3NZ9 X;  1AOE A;  1HFR A;  1DHF A;  1LY3 A;  4Q6A A;  3F0Q X;  3GI2 A;  4G8Z X;  3FRD X;  1DRB A;  3F91 A;  1S3Y A;  1DRH A;  5HQZ A;  3QLS A;  3QLZ A;  4KNE A;  2HXV A;  4M7U A;  5HQY A;  1LUD A;  4EJ1 A;  1J3K A;  2W3A A;  4XT7 A;  1RX3 A;  1AI9 A;  5ECC A;  1MVT A;  4KBN A;  3F0X X;  3E0B A;  2OIP A;  4OSG A;  2GD9 A;  5DFR A;  4M2X A;  1RG7 A;  4PST A;  4PDJ A;  1RX5 A;  1RA3 A;  3SRU X;  3QLY A;  3QYO A;  4X5I A;  1RX1 A;  5U27 A;  1DHJ A;  1U71 A;  2C2T A;  7DFR A;  1OHK A;  2DRC A;  1RX6 A;  3JSU A;  2CIG A;  4QJZ D;  1DYR A;  4XEC X;  3TQ8 A;  4QLF A;  3CD2 A;  4PSS A;  4XT6 A;  4TU5 X;  1JUV A;  3JWM A;  1DG8 A;  3UM6 A;  3I8A X;  1DRA A;  2ANO A;  2W3M A;  4KM0 A;  3IRM A;  2JYB A;  1RX7 A;  2O7P A;  4ECK A;  4KJK A;  2CD2 A;  2D0K A;  1VDR A;  2INQ A;  4XRB A;  4G95 A;  4XT8 A;  1DIU A;  1DG7 A;  3R33 A;  3ZPG A;  4PTJ A;  3DGA A;  3QLR A;  1U70 A;  3DAU A;  1RD7 A;  3QLX A;  4NX7 A;  1KLK A;  1DR1 A;  3NTZ A;  1QZF A;  2W9G A;  3GHW A;  4KEB A;  4IXF X;  4X5G A;  3DG8 A;  3SQY X;  3EX8 A;  8DFR A;  1IA4 A;  1ZDR A;  1AO8 A;  1RX2 A;  3INV A;  3NXT A;  3NXV A;  3JW5 A;  3JWK A;  1J3I A;  1DR7 A;  3IX9 A;  3K74 A;  4KAK A;  1RB2 A;  3KGY A;  1DDS A;  4QJC A;  3F8Z A;  1IA1 A;  3GHC A;  5HVE A;  3RG9 A;  4XT4 A;  2L28 A;  4I13 A;  4DFR A;  3NXR A;  3UM5 A;  3ROA A;  3QFX A;  3QGT A;  5ECX A;  2W3V A;  2ZZA A;  4HA9 A;  3FL9 A;  4P3Q A;  3F0S X;  1J3J A;  3NZ6 X;  1DRF A;  1TDR A;  1U72 A;  3VCO A;  3FRA X;  3QLW A;  5HUI A;  3FQZ A;  3Q1H A;  3CLB A;  2BLA A;  2BLB A;  4X5J A;  1DYJ A;  4P3R A;  2P4G A;  3QL3 A;  1RC4 A;  1HFP A;  4P68 A;  1RX8 A;  2XW7 A;  4XE6 X;  4ELG A;  3FS6 A;  3FQF A;  3FRE X;  4P66 A;  3EIG A;  3QG2 A;  2HQP A;  3HJ3 A;  4Q0D A;  1BZF A;  2B3Z A;  1KMS A;  4X5H A;  3FYW X;  2ITH A;  1DAJ A;  4M6K A;  4KJJ A;  4H98 A;  1E26 A;  2BLC A;  1DYI A;  4H96 A;  3TQA A;  5HVB A;  3SR5 X;  3F0U X;  3JWF A;  3QL0 A;  4QLG A;  1DG5 A;  3SGY A;  4FGG A;  1RH3 A;  1JOL A;  3OAF A;  1DR6 A;  3JTW A;  4X5F A;  1DR3 A;  3K2H A;  4QHV A;  1OHJ A;  1PD9 A;  4KM2 A;  2W9T A;  3F8Y A;  5HI6 A;  2QK8 A;  1DR2 A;  3SA2 A;  4M6J A;  1MVS A;  4GH8 A;  3K45 A;  3DRC A;  1S3U A;  3TD8 A;  1IA3 A;  4QI9 A;  2HM9 A;  3LG4 A;  2ANQ A;  4ELE A;  4ELB A;  3L3R A;  3NZD A;  1VJ3 A;  5JG0 X;  2BL9 A;  2H2Q A;  4H95 A;  3KY8 A;  1RX4 A;  3FL8 A;  1DYH A;  3NXO A;  1M79 A;  3SRW X;  3F0B X;  3NXY A;  4ELH A;  3CL9 A;  5FDA A;  5HT5 A;  4H97 A;  3KJR A;  3K47 A;  3D84 X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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