4KNEA

Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis in complex with cycloguanil
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
159
structure length
159
Chain Sequence
MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mycobacterium tuberculosis Dihydrofolate Reductase Reveals Two Conformational States and a Possible Low Affinity Mechanism to Antifolate Drugs.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mycobacterium tuberculosis
molecule keywords Dihydrofolate reductase
total genus 43
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2013-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4kneA00
1DYHA 1CZ3A 4HA7A 1DDSA 1LY4A 3HJ3A 4H97A 3SGYA 3FQFA 3KFYA 4X5JA 4H96A 4KLXA 3JVXA 4XT7A 2HXVA 3FQZA 1S3VA 5FDAA 1RX3A 4KYAA 5ECCA 2DHFA 1U70A 4RGCA 3KJSA 3IRNA 4KY4A 3E0BA 2W9GA 3FS6A 3QYLA 4FHBA 5CC9A 4P66A 5JG0X 4GH8A 3CSEA 3KY8A 3DAUA 4Q6AA 1PD9A 5HT5A 2OIPA 1RX6A 3JWMA 4KD7A 4KAKA 3JSUA 3QFXA 3GYFA 1DR7A 3DGAA 3EEJA 4KEBA 3RO9A 2LF1A 4KM2A 3JW5A 4QLGA 1HFRA 1DAJA 5HT4A 3SH2A 1SEJA 4FGGA 3IA5A 4OR7A 1KMSA 4PSTA 3FQOA 3QL0A 3ZPGA 2CIGA 3INVA 3I3RA 4IXFX 4Q0EA 1RB2A 1KLKA 2FZJA 3NXXA 1DLSA 3NXOA 4DDRA 1RA9A 3NXYA 2KGKA 3FQCA 3TQAA 1DRBA 4I1NA 1RX9A 4G3MA 5HUIA 3DG8A 3QLYA 1MVSA 2C2TA 2ANOA 5HF2X 3SRSX 4EJ1A 4M6KA 3K45A 1DR2A 2JYBA 3LG4A 5HSRA 2CD2A 3NXTA 3GHCA 4DPDA 2O7PA 4QLEA 3FQ0A 3NZDA 3QLWA 4QHVA 3SRWX 3EEMA 2QK8A 3K47A 4KFJA 1J3JA 1RX1A 4PSYA 5HSUA 1IA1A 4NX7A 2B3ZA 3NZBX 5U27A 3JWFA 3F8ZA 1AI9A 3FY9X 3SQYX 3CLBA 3EX8A 3JWKA 4EIGA 5EAJA 1J3IA 1RX5A 4PTJA 5HF0X 4KNEA 3IRMA 3F91A 1DHJA 2W3AA 3F8YA 1RA8A 3QG2A 4LEKX 4HOFA 3CD2A 3QGTA 1M78A 4XT6A 2W9HA 1HFQA 3DATA 1AO8A 3NZ9X 1AOEA 3DFRA 4X5FA 3EELA 1LY3A 3FRBX 1OHKA 3GHVA 1DR4A 3EIGA 2W9SA 3JW3A 4QI9A 3FQVA 1RE7A 3FRFX 3NU0A 3KGYA 3NTZA 3S9UA 3ZPCA 4IXED 4KL9A 3K74A 4KJJA 4M2XA 4ELGA 3I8AX 4PTHA 5CCCA 3K2HA 3TQBA 2H2QA 4XECX 2W3BA 3SR5X 3KJRA 3QLZA 1DHFA 3OCHA 3VCOA 3M09A 1DRFA 1YHOA 3EEKA 3S7AA 4DFRA 2AZNA 4HA9A 4NX6A 3FRDX 1E26A 4PSSA 3F0VX 2W3MA 3M08A 1JOLA 4CD2A 2BLBA 3NRRA 4PDJA 1JOMA 4DPHA 5ECXA 5HPBA 3F0XX 1RC4A 1DREA 1J3KA 4ELBA 3IROA 1JUVA 1DLRA 1RG7A 4KJKA 4XRBA 3FYVX 4Q67A 1M7AA 4ELEA 1RB3A 2HM9A 3SA2A 3F0BX 3QLSA 1LUDA 1RX8A 1S3UA 5JA3A 1DR6A 3CL9A 1BZFA 1DISA 1DR5A 1DG5A 3NZCX 4M6LA 2L28A 4HOGA 3HBBA 3DRCA 2ZZAA 4KBNA 1DDRA 4ECKA 3F0SX 4KM0A 1DYJA 2INQA 4KY8A 1DRAA 3SA1A 4DP3A 3SRRX 3NZAX 1RA1A 1RA3A 2BLCA 1VJ3A 3FYWX 1RX2A 2FZHA 4X5GA 3TD8A 1RH3A 2W3VA 2D0KA 2W9TA 1D1GA 4QLFA 4LAEX 3GI2A 3UM5A 5U26A 3R33A 1DHIA 4KJLA 3FL8A 3FRAX 3FY8X 1VDRA 3SRUX 3D80A 3L3RA 1IA4A 3SRQX 5E8QA 1OHJA 4HOEA 3QLXA 3ROAA 1QZFA 3NXRA 3DL5A 4X5IA 1DYIA 5DFRA 1U71A 1IA3A 1DG7A 4G8ZX 3NXVA 4IXGX 3QYOA 6DFRA 2C2SA 5HI6A 4OSGA 4FGHA 2BL9A 3N0HA 2ANQA 4P3RA 1S3YA 3TQ9A 1S3WA 1DR3A 2ITHA 4ELFA 1KMVA 1RD7A 3IA4A 1DIUA 4XT5A 1DF7A 3SAIA 3FL9A 3NZ6X 3IX9A 4Q0DA 1ZDRA 1BOZA 4M7VA 7DFRA 8DFRA 5HQYA 1RF7A 4QJZD 3Q1HA 3FREX 2BLAA 1M79A 3D84X 4LAGX 3QL3A 4TU5X 2P4GA 1HFPA 1RA2A 2D5NA 2OBCA 3GHWA 3UM8A 3JWCA 4XT8A 2DRCA 4ELHA 5HQZA 3RG9A 1DYRA 3DL6A 3UM6A 3F0UX 2G6VA 5HVEA 1U72A 2GD9A 3QLRA 1CD2A 4G95A 3TQ8A 4H98A 4P3QA 4P68A 1DR1A 4X5HA 4M7UA 4EIZA 3JTWA 2HQPA 1DG8A 1DRHA 1RX4A 2W3WA 2XW7A 3F0QX 1RX7A 1IA2A 1PDBA 4M6JA 2FZIA 4I13A 4QJCA 3S3VA 4LAHX 4EILA 1TDRA 1MVTA 4XE6X 3OAFA 4XT4A 4H95A 5HVBA 5DXVA 1PD8A
chains in the Genus database with same CATH superfamily
1DYHA 1CZ3A 4HA7A 1DDSA 1LY4A 3HJ3A 4H97A 3SGYA 3FQFA 3KFYA 4X5JA 4H96A 4KLXA 3JVXA 4XT7A 2HXVA 3FQZA 1S3VA 5FDAA 1RX3A 4KYAA 5ECCA 2DHFA 1U70A 4RGCA 3KJSA 3IRNA 4KY4A 3E0BA 2W9GA 3FS6A 3QYLA 4FHBA 5CC9A 4P66A 5JG0X 4GH8A 3CSEA 3KY8A 3DAUA 4Q6AA 1PD9A 5HT5A 2OIPA 1RX6A 3JWMA 4KD7A 4KAKA 3JSUA 3QFXA 3GYFA 1DR7A 3DGAA 3EEJA 4KEBA 3RO9A 2LF1A 4KM2A 3JW5A 4QLGA 1HFRA 1DAJA 5HT4A 3SH2A 1SEJA 4FGGA 3IA5A 4OR7A 1KMSA 4PSTA 3FQOA 3QL0A 3ZPGA 2CIGA 3INVA 3I3RA 4IXFX 4Q0EA 1RB2A 1KLKA 2FZJA 3NXXA 1DLSA 3NXOA 4DDRA 1RA9A 3NXYA 2KGKA 3FQCA 3TQAA 1DRBA 4I1NA 1RX9A 4G3MA 5HUIA 3DG8A 3QLYA 1MVSA 2C2TA 2ANOA 5HF2X 3SRSX 4EJ1A 4M6KA 3K45A 1DR2A 2JYBA 3LG4A 5HSRA 2CD2A 3NXTA 3GHCA 4DPDA 2O7PA 4QLEA 3FQ0A 3NZDA 3QLWA 4QHVA 3SRWX 3EEMA 2QK8A 3K47A 4KFJA 1J3JA 1RX1A 4PSYA 5HSUA 1IA1A 4NX7A 2B3ZA 3NZBX 5U27A 3JWFA 3F8ZA 1AI9A 3FY9X 3SQYX 3CLBA 3EX8A 3JWKA 4EIGA 5EAJA 1J3IA 1RX5A 4PTJA 5HF0X 4KNEA 3IRMA 3F91A 1DHJA 2W3AA 3F8YA 1RA8A 3QG2A 4LEKX 4HOFA 3CD2A 3QGTA 1M78A 4XT6A 2W9HA 1HFQA 3DATA 1AO8A 3NZ9X 1AOEA 3DFRA 4X5FA 3EELA 1LY3A 3FRBX 1OHKA 3GHVA 1DR4A 3EIGA 2W9SA 3JW3A 4QI9A 3FQVA 1RE7A 3FRFX 3NU0A 3KGYA 3NTZA 3S9UA 3ZPCA 4IXED 4KL9A 3K74A 4KJJA 4M2XA 4ELGA 3I8AX 4PTHA 5CCCA 3K2HA 3TQBA 2H2QA 4XECX 2W3BA 3SR5X 3KJRA 3QLZA 1DHFA 3OCHA 3VCOA 3M09A 1DRFA 1YHOA 3EEKA 3S7AA 4DFRA 2AZNA 4HA9A 4NX6A 3FRDX 1E26A 4PSSA 3F0VX 2W3MA 3M08A 1JOLA 4CD2A 2BLBA 3NRRA 4PDJA 1JOMA 4DPHA 5ECXA 5HPBA 3F0XX 1RC4A 1DREA 1J3KA 4ELBA 3IROA 1JUVA 1DLRA 1RG7A 4KJKA 4XRBA 3FYVX 4Q67A 1M7AA 4ELEA 1RB3A 2HM9A 3SA2A 3F0BX 3QLSA 1LUDA 1RX8A 1S3UA 5JA3A 1DR6A 3CL9A 1BZFA 1DISA 1DR5A 1DG5A 3NZCX 4M6LA 2L28A 4HOGA 3HBBA 3DRCA 2ZZAA 4KBNA 1DDRA 4ECKA 3F0SX 4KM0A 1DYJA 2INQA 4KY8A 1DRAA 3SA1A 4DP3A 3SRRX 3NZAX 1RA1A 1RA3A 2BLCA 1VJ3A 3FYWX 1RX2A 2FZHA 4X5GA 3TD8A 1RH3A 2W3VA 2D0KA 2W9TA 1D1GA 4QLFA 4LAEX 3GI2A 3UM5A 5U26A 3R33A 1DHIA 4KJLA 3FL8A 3FRAX 3FY8X 1VDRA 3SRUX 3D80A 3L3RA 1IA4A 3SRQX 5E8QA 1OHJA 4HOEA 3QLXA 3ROAA 1QZFA 3NXRA 3DL5A 4X5IA 1DYIA 5DFRA 1U71A 1IA3A 1DG7A 4G8ZX 3NXVA 4IXGX 3QYOA 6DFRA 2C2SA 5HI6A 4OSGA 4FGHA 2BL9A 3N0HA 2ANQA 4P3RA 1S3YA 3TQ9A 1S3WA 1DR3A 2ITHA 4ELFA 1KMVA 1RD7A 3IA4A 1DIUA 4XT5A 1DF7A 3SAIA 3FL9A 3NZ6X 3IX9A 4Q0DA 1ZDRA 1BOZA 4M7VA 7DFRA 8DFRA 5HQYA 1RF7A 4QJZD 3Q1HA 3FREX 2BLAA 1M79A 3D84X 4LAGX 3QL3A 4TU5X 2P4GA 1HFPA 1RA2A 2D5NA 2OBCA 3GHWA 3UM8A 3JWCA 4XT8A 2DRCA 4ELHA 5HQZA 3RG9A 1DYRA 3DL6A 3UM6A 3F0UX 2G6VA 5HVEA 1U72A 2GD9A 3QLRA 1CD2A 4G95A 3TQ8A 4H98A 4P3QA 4P68A 1DR1A 4X5HA 4M7UA 4EIZA 3JTWA 2HQPA 1DG8A 1DRHA 1RX4A 2W3WA 2XW7A 3F0QX 1RX7A 1IA2A 1PDBA 4M6JA 2FZIA 4I13A 4QJCA 3S3VA 4LAHX 4EILA 1TDRA 1MVTA 4XE6X 3OAFA 4XT4A 4H95A 5HVBA 5DXVA 1PD8A
chains in the Genus database with same CATH topology
1DYHA 1CZ3A 4HA7A 1DDSA 1LY4A 3HJ3A 4H97A 3SGYA 3FQFA 3KFYA 4X5JA 4H96A 4KLXA 3JVXA 4XT7A 2HXVA 3FQZA 1S3VA 5FDAA 1RX3A 4KYAA 5ECCA 2DHFA 1U70A 4RGCA 3KJSA 3IRNA 4KY4A 3E0BA 2W9GA 3FS6A 3QYLA 4FHBA 5CC9A 4P66A 5JG0X 4GH8A 3CSEA 3KY8A 3DAUA 4Q6AA 1PD9A 5HT5A 2OIPA 1RX6A 3JWMA 4KD7A 4KAKA 3JSUA 3QFXA 3GYFA 1DR7A 3DGAA 3EEJA 4KEBA 3RO9A 2LF1A 4KM2A 3JW5A 4QLGA 1HFRA 1DAJA 5HT4A 3SH2A 1SEJA 4FGGA 3IA5A 4OR7A 1KMSA 4PSTA 3FQOA 3QL0A 3ZPGA 2CIGA 3INVA 3I3RA 4IXFX 4Q0EA 1RB2A 1KLKA 2FZJA 3NXXA 1DLSA 3NXOA 4DDRA 1RA9A 3NXYA 2KGKA 3FQCA 3TQAA 1DRBA 4I1NA 1RX9A 4G3MA 5HUIA 3DG8A 3QLYA 1MVSA 2C2TA 2ANOA 5HF2X 3SRSX 4EJ1A 4M6KA 3K45A 1DR2A 2JYBA 3LG4A 5HSRA 2CD2A 3NXTA 3GHCA 4DPDA 2O7PA 4QLEA 3FQ0A 3NZDA 3QLWA 4QHVA 3SRWX 3EEMA 2QK8A 3K47A 4KFJA 1J3JA 1RX1A 4PSYA 5HSUA 1IA1A 4NX7A 2B3ZA 3NZBX 5U27A 3JWFA 3F8ZA 1AI9A 3FY9X 3SQYX 3CLBA 3EX8A 3JWKA 4EIGA 5EAJA 1J3IA 1RX5A 4PTJA 5HF0X 4KNEA 3IRMA 3F91A 1DHJA 2W3AA 3F8YA 1RA8A 3QG2A 4LEKX 4HOFA 3CD2A 3QGTA 1M78A 4XT6A 2W9HA 1HFQA 3DATA 1AO8A 3NZ9X 1AOEA 3DFRA 4X5FA 3EELA 1LY3A 3FRBX 1OHKA 3GHVA 1DR4A 3EIGA 2W9SA 3JW3A 4QI9A 3FQVA 1RE7A 3FRFX 3NU0A 3KGYA 3NTZA 3S9UA 3ZPCA 4IXED 4KL9A 3K74A 4KJJA 4M2XA 4ELGA 3I8AX 4PTHA 5CCCA 3K2HA 3TQBA 2H2QA 4XECX 2W3BA 3SR5X 3KJRA 3QLZA 1DHFA 3OCHA 3VCOA 3M09A 1DRFA 1YHOA 3EEKA 3S7AA 4DFRA 2AZNA 4HA9A 4NX6A 3FRDX 1E26A 4PSSA 3F0VX 2W3MA 3M08A 1JOLA 4CD2A 2BLBA 3NRRA 4PDJA 1JOMA 4DPHA 5ECXA 5HPBA 3F0XX 1RC4A 1DREA 1J3KA 4ELBA 3IROA 1JUVA 1DLRA 1RG7A 4KJKA 4XRBA 3FYVX 4Q67A 1M7AA 4ELEA 1RB3A 2HM9A 3SA2A 3F0BX 3QLSA 1LUDA 1RX8A 1S3UA 5JA3A 1DR6A 3CL9A 1BZFA 1DISA 1DR5A 1DG5A 3NZCX 4M6LA 2L28A 4HOGA 3HBBA 3DRCA 2ZZAA 4KBNA 1DDRA 4ECKA 3F0SX 4KM0A 1DYJA 2INQA 4KY8A 1DRAA 3SA1A 4DP3A 3SRRX 3NZAX 1RA1A 1RA3A 2BLCA 1VJ3A 3FYWX 1RX2A 2FZHA 4X5GA 3TD8A 1RH3A 2W3VA 2D0KA 2W9TA 1D1GA 4QLFA 4LAEX 3GI2A 3UM5A 5U26A 3R33A 1DHIA 4KJLA 3FL8A 3FRAX 3FY8X 1VDRA 3SRUX 3D80A 3L3RA 1IA4A 3SRQX 5E8QA 1OHJA 4HOEA 3QLXA 3ROAA 1QZFA 3NXRA 3DL5A 4X5IA 1DYIA 5DFRA 1U71A 1IA3A 1DG7A 4G8ZX 3NXVA 4IXGX 3QYOA 6DFRA 2C2SA 5HI6A 4OSGA 4FGHA 2BL9A 3N0HA 2ANQA 4P3RA 1S3YA 3TQ9A 1S3WA 1DR3A 2ITHA 4ELFA 1KMVA 1RD7A 3IA4A 1DIUA 4XT5A 1DF7A 3SAIA 3FL9A 3NZ6X 3IX9A 4Q0DA 1ZDRA 1BOZA 4M7VA 7DFRA 8DFRA 5HQYA 1RF7A 4QJZD 3Q1HA 3FREX 2BLAA 1M79A 3D84X 4LAGX 3QL3A 4TU5X 2P4GA 1HFPA 1RA2A 2D5NA 2OBCA 3GHWA 3UM8A 3JWCA 4XT8A 2DRCA 4ELHA 5HQZA 3RG9A 1DYRA 3DL6A 3UM6A 3F0UX 2G6VA 5HVEA 1U72A 2GD9A 3QLRA 1CD2A 4G95A 3TQ8A 4H98A 4P3QA 4P68A 1DR1A 4X5HA 4M7UA 4EIZA 3JTWA 2HQPA 1DG8A 1DRHA 1RX4A 2W3WA 2XW7A 3F0QX 1RX7A 1IA2A 1PDBA 4M6JA 2FZIA 4I13A 4QJCA 3S3VA 4LAHX 4EILA 1TDRA 1MVTA 4XE6X 3OAFA 4XT4A 4H95A 5HVBA 5DXVA 1PD8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DYH A;  1CZ3 A;  4HA7 A;  1DDS A;  1LY4 A;  3HJ3 A;  4H97 A;  3SGY A;  3FQF A;  3KFY A;  4X5J A;  4H96 A;  4KLX A;  3JVX A;  4XT7 A;  2HXV A;  3FQZ A;  1S3V A;  5FDA A;  1RX3 A;  4KYA A;  5ECC A;  2DHF A;  1U70 A;  4RGC A;  3KJS A;  3IRN A;  4KY4 A;  3E0B A;  2W9G A;  3FS6 A;  3QYL A;  4FHB A;  5CC9 A;  4P66 A;  5JG0 X;  4GH8 A;  3CSE A;  3KY8 A;  3DAU A;  4Q6A A;  1PD9 A;  5HT5 A;  2OIP A;  1RX6 A;  3JWM A;  4KD7 A;  4KAK A;  3JSU A;  3QFX A;  3GYF A;  1DR7 A;  3DGA A;  3EEJ A;  4KEB A;  3RO9 A;  2LF1 A;  4KM2 A;  3JW5 A;  4QLG A;  1HFR A;  1DAJ A;  5HT4 A;  3SH2 A;  1SEJ A;  4FGG A;  3IA5 A;  4OR7 A;  1KMS A;  4PST A;  3FQO A;  3QL0 A;  3ZPG A;  2CIG A;  3INV A;  3I3R A;  4IXF X;  4Q0E A;  1RB2 A;  1KLK A;  2FZJ A;  3NXX A;  1DLS A;  3NXO A;  4DDR A;  1RA9 A;  3NXY A;  2KGK A;  3FQC A;  3TQA A;  1DRB A;  4I1N A;  1RX9 A;  4G3M A;  5HUI A;  3DG8 A;  3QLY A;  1MVS A;  2C2T A;  2ANO A;  5HF2 X;  3SRS X;  4EJ1 A;  4M6K A;  3K45 A;  1DR2 A;  2JYB A;  3LG4 A;  5HSR A;  2CD2 A;  3NXT A;  3GHC A;  4DPD A;  2O7P A;  4QLE A;  3FQ0 A;  3NZD A;  3QLW A;  4QHV A;  3SRW X;  3EEM A;  2QK8 A;  3K47 A;  4KFJ A;  1J3J A;  1RX1 A;  4PSY A;  5HSU A;  1IA1 A;  4NX7 A;  2B3Z A;  3NZB X;  5U27 A;  3JWF A;  3F8Z A;  1AI9 A;  3FY9 X;  3SQY X;  3CLB A;  3EX8 A;  3JWK A;  4EIG A;  5EAJ A;  1J3I A;  1RX5 A;  4PTJ A;  5HF0 X;  4KNE A;  3IRM A;  3F91 A;  1DHJ A;  2W3A A;  3F8Y A;  1RA8 A;  3QG2 A;  4LEK X;  4HOF A;  3CD2 A;  3QGT A;  1M78 A;  4XT6 A;  2W9H A;  1HFQ A;  3DAT A;  1AO8 A;  3NZ9 X;  1AOE A;  3DFR A;  4X5F A;  3EEL A;  1LY3 A;  3FRB X;  1OHK A;  3GHV A;  1DR4 A;  3EIG A;  2W9S A;  3JW3 A;  4QI9 A;  3FQV A;  1RE7 A;  3FRF X;  3NU0 A;  3KGY A;  3NTZ A;  3S9U A;  3ZPC A;  4IXE D;  4KL9 A;  3K74 A;  4KJJ A;  4M2X A;  4ELG A;  3I8A X;  4PTH A;  5CCC A;  3K2H A;  3TQB A;  2H2Q A;  4XEC X;  2W3B A;  3SR5 X;  3KJR A;  3QLZ A;  1DHF A;  3OCH A;  3VCO A;  3M09 A;  1DRF A;  1YHO A;  3EEK A;  3S7A A;  4DFR A;  2AZN A;  4HA9 A;  4NX6 A;  3FRD X;  1E26 A;  4PSS A;  3F0V X;  2W3M A;  3M08 A;  1JOL A;  4CD2 A;  2BLB A;  3NRR A;  4PDJ A;  1JOM A;  4DPH A;  5ECX A;  5HPB A;  3F0X X;  1RC4 A;  1DRE A;  1J3K A;  4ELB A;  3IRO A;  1JUV A;  1DLR A;  1RG7 A;  4KJK A;  4XRB A;  3FYV X;  4Q67 A;  1M7A A;  4ELE A;  1RB3 A;  2HM9 A;  3SA2 A;  3F0B X;  3QLS A;  1LUD A;  1RX8 A;  1S3U A;  5JA3 A;  1DR6 A;  3CL9 A;  1BZF A;  1DIS A;  1DR5 A;  1DG5 A;  3NZC X;  4M6L A;  2L28 A;  4HOG A;  3HBB A;  3DRC A;  2ZZA A;  4KBN A;  1DDR A;  4ECK A;  3F0S X;  4KM0 A;  1DYJ A;  2INQ A;  4KY8 A;  1DRA A;  3SA1 A;  4DP3 A;  3SRR X;  3NZA X;  1RA1 A;  1RA3 A;  2BLC A;  1VJ3 A;  3FYW X;  1RX2 A;  2FZH A;  4X5G A;  3TD8 A;  1RH3 A;  2W3V A;  2D0K A;  2W9T A;  1D1G A;  4QLF A;  4LAE X;  3GI2 A;  3UM5 A;  5U26 A;  3R33 A;  1DHI A;  4KJL A;  3FL8 A;  3FRA X;  3FY8 X;  1VDR A;  3SRU X;  3D80 A;  3L3R A;  1IA4 A;  3SRQ X;  5E8Q A;  1OHJ A;  4HOE A;  3QLX A;  3ROA A;  1QZF A;  3NXR A;  3DL5 A;  4X5I A;  1DYI A;  5DFR A;  1U71 A;  1IA3 A;  1DG7 A;  4G8Z X;  3NXV A;  4IXG X;  3QYO A;  6DFR A;  2C2S A;  5HI6 A;  4OSG A;  4FGH A;  2BL9 A;  3N0H A;  2ANQ A;  4P3R A;  1S3Y A;  3TQ9 A;  1S3W A;  1DR3 A;  2ITH A;  4ELF A;  1KMV A;  1RD7 A;  3IA4 A;  1DIU A;  4XT5 A;  1DF7 A;  3SAI A;  3FL9 A;  3NZ6 X;  3IX9 A;  4Q0D A;  1ZDR A;  1BOZ A;  4M7V A;  7DFR A;  8DFR A;  5HQY A;  1RF7 A;  4QJZ D;  3Q1H A;  3FRE X;  2BLA A;  1M79 A;  3D84 X;  4LAG X;  3QL3 A;  4TU5 X;  2P4G A;  1HFP A;  1RA2 A;  2D5N A;  2OBC A;  3GHW A;  3UM8 A;  3JWC A;  4XT8 A;  2DRC A;  4ELH A;  5HQZ A;  3RG9 A;  1DYR A;  3DL6 A;  3UM6 A;  3F0U X;  2G6V A;  5HVE A;  1U72 A;  2GD9 A;  3QLR A;  1CD2 A;  4G95 A;  3TQ8 A;  4H98 A;  4P3Q A;  4P68 A;  1DR1 A;  4X5H A;  4M7U A;  4EIZ A;  3JTW A;  2HQP A;  1DG8 A;  1DRH A;  1RX4 A;  2W3W A;  2XW7 A;  3F0Q X;  1RX7 A;  1IA2 A;  1PDB A;  4M6J A;  2FZI A;  4I13 A;  4QJC A;  3S3V A;  4LAH X;  4EIL A;  1TDR A;  1MVT A;  4XE6 X;  3OAF A;  4XT4 A;  4H95 A;  5HVB A;  5DXV A;  1PD8 A; 
#chains in the Genus database with same CATH topology
 1DYH A;  1CZ3 A;  4HA7 A;  1DDS A;  1LY4 A;  3HJ3 A;  4H97 A;  3SGY A;  3FQF A;  3KFY A;  4X5J A;  4H96 A;  4KLX A;  3JVX A;  4XT7 A;  2HXV A;  3FQZ A;  1S3V A;  5FDA A;  1RX3 A;  4KYA A;  5ECC A;  2DHF A;  1U70 A;  4RGC A;  3KJS A;  3IRN A;  4KY4 A;  3E0B A;  2W9G A;  3FS6 A;  3QYL A;  4FHB A;  5CC9 A;  4P66 A;  5JG0 X;  4GH8 A;  3CSE A;  3KY8 A;  3DAU A;  4Q6A A;  1PD9 A;  5HT5 A;  2OIP A;  1RX6 A;  3JWM A;  4KD7 A;  4KAK A;  3JSU A;  3QFX A;  3GYF A;  1DR7 A;  3DGA A;  3EEJ A;  4KEB A;  3RO9 A;  2LF1 A;  4KM2 A;  3JW5 A;  4QLG A;  1HFR A;  1DAJ A;  5HT4 A;  3SH2 A;  1SEJ A;  4FGG A;  3IA5 A;  4OR7 A;  1KMS A;  4PST A;  3FQO A;  3QL0 A;  3ZPG A;  2CIG A;  3INV A;  3I3R A;  4IXF X;  4Q0E A;  1RB2 A;  1KLK A;  2FZJ A;  3NXX A;  1DLS A;  3NXO A;  4DDR A;  1RA9 A;  3NXY A;  2KGK A;  3FQC A;  3TQA A;  1DRB A;  4I1N A;  1RX9 A;  4G3M A;  5HUI A;  3DG8 A;  3QLY A;  1MVS A;  2C2T A;  2ANO A;  5HF2 X;  3SRS X;  4EJ1 A;  4M6K A;  3K45 A;  1DR2 A;  2JYB A;  3LG4 A;  5HSR A;  2CD2 A;  3NXT A;  3GHC A;  4DPD A;  2O7P A;  4QLE A;  3FQ0 A;  3NZD A;  3QLW A;  4QHV A;  3SRW X;  3EEM A;  2QK8 A;  3K47 A;  4KFJ A;  1J3J A;  1RX1 A;  4PSY A;  5HSU A;  1IA1 A;  4NX7 A;  2B3Z A;  3NZB X;  5U27 A;  3JWF A;  3F8Z A;  1AI9 A;  3FY9 X;  3SQY X;  3CLB A;  3EX8 A;  3JWK A;  4EIG A;  5EAJ A;  1J3I A;  1RX5 A;  4PTJ A;  5HF0 X;  4KNE A;  3IRM A;  3F91 A;  1DHJ A;  2W3A A;  3F8Y A;  1RA8 A;  3QG2 A;  4LEK X;  4HOF A;  3CD2 A;  3QGT A;  1M78 A;  4XT6 A;  2W9H A;  1HFQ A;  3DAT A;  1AO8 A;  3NZ9 X;  1AOE A;  3DFR A;  4X5F A;  3EEL A;  1LY3 A;  3FRB X;  1OHK A;  3GHV A;  1DR4 A;  3EIG A;  2W9S A;  3JW3 A;  4QI9 A;  3FQV A;  1RE7 A;  3FRF X;  3NU0 A;  3KGY A;  3NTZ A;  3S9U A;  3ZPC A;  4IXE D;  4KL9 A;  3K74 A;  4KJJ A;  4M2X A;  4ELG A;  3I8A X;  4PTH A;  5CCC A;  3K2H A;  3TQB A;  2H2Q A;  4XEC X;  2W3B A;  3SR5 X;  3KJR A;  3QLZ A;  1DHF A;  3OCH A;  3VCO A;  3M09 A;  1DRF A;  1YHO A;  3EEK A;  3S7A A;  4DFR A;  2AZN A;  4HA9 A;  4NX6 A;  3FRD X;  1E26 A;  4PSS A;  3F0V X;  2W3M A;  3M08 A;  1JOL A;  4CD2 A;  2BLB A;  3NRR A;  4PDJ A;  1JOM A;  4DPH A;  5ECX A;  5HPB A;  3F0X X;  1RC4 A;  1DRE A;  1J3K A;  4ELB A;  3IRO A;  1JUV A;  1DLR A;  1RG7 A;  4KJK A;  4XRB A;  3FYV X;  4Q67 A;  1M7A A;  4ELE A;  1RB3 A;  2HM9 A;  3SA2 A;  3F0B X;  3QLS A;  1LUD A;  1RX8 A;  1S3U A;  5JA3 A;  1DR6 A;  3CL9 A;  1BZF A;  1DIS A;  1DR5 A;  1DG5 A;  3NZC X;  4M6L A;  2L28 A;  4HOG A;  3HBB A;  3DRC A;  2ZZA A;  4KBN A;  1DDR A;  4ECK A;  3F0S X;  4KM0 A;  1DYJ A;  2INQ A;  4KY8 A;  1DRA A;  3SA1 A;  4DP3 A;  3SRR X;  3NZA X;  1RA1 A;  1RA3 A;  2BLC A;  1VJ3 A;  3FYW X;  1RX2 A;  2FZH A;  4X5G A;  3TD8 A;  1RH3 A;  2W3V A;  2D0K A;  2W9T A;  1D1G A;  4QLF A;  4LAE X;  3GI2 A;  3UM5 A;  5U26 A;  3R33 A;  1DHI A;  4KJL A;  3FL8 A;  3FRA X;  3FY8 X;  1VDR A;  3SRU X;  3D80 A;  3L3R A;  1IA4 A;  3SRQ X;  5E8Q A;  1OHJ A;  4HOE A;  3QLX A;  3ROA A;  1QZF A;  3NXR A;  3DL5 A;  4X5I A;  1DYI A;  5DFR A;  1U71 A;  1IA3 A;  1DG7 A;  4G8Z X;  3NXV A;  4IXG X;  3QYO A;  6DFR A;  2C2S A;  5HI6 A;  4OSG A;  4FGH A;  2BL9 A;  3N0H A;  2ANQ A;  4P3R A;  1S3Y A;  3TQ9 A;  1S3W A;  1DR3 A;  2ITH A;  4ELF A;  1KMV A;  1RD7 A;  3IA4 A;  1DIU A;  4XT5 A;  1DF7 A;  3SAI A;  3FL9 A;  3NZ6 X;  3IX9 A;  4Q0D A;  1ZDR A;  1BOZ A;  4M7V A;  7DFR A;  8DFR A;  5HQY A;  1RF7 A;  4QJZ D;  3Q1H A;  3FRE X;  2BLA A;  1M79 A;  3D84 X;  4LAG X;  3QL3 A;  4TU5 X;  2P4G A;  1HFP A;  1RA2 A;  2D5N A;  2OBC A;  3GHW A;  3UM8 A;  3JWC A;  4XT8 A;  2DRC A;  4ELH A;  5HQZ A;  3RG9 A;  1DYR A;  3DL6 A;  3UM6 A;  3F0U X;  2G6V A;  5HVE A;  1U72 A;  2GD9 A;  3QLR A;  1CD2 A;  4G95 A;  3TQ8 A;  4H98 A;  4P3Q A;  4P68 A;  1DR1 A;  4X5H A;  4M7U A;  4EIZ A;  3JTW A;  2HQP A;  1DG8 A;  1DRH A;  1RX4 A;  2W3W A;  2XW7 A;  3F0Q X;  1RX7 A;  1IA2 A;  1PDB A;  4M6J A;  2FZI A;  4I13 A;  4QJC A;  3S3V A;  4LAH X;  4EIL A;  1TDR A;  1MVT A;  4XE6 X;  3OAF A;  4XT4 A;  4H95 A;  5HVB A;  5DXV A;  1PD8 A; 
#chains in the Genus database with same CATH homology
 1DYH A;  1CZ3 A;  4HA7 A;  1DDS A;  1LY4 A;  3HJ3 A;  4H97 A;  3SGY A;  3FQF A;  3KFY A;  4X5J A;  4H96 A;  4KLX A;  3JVX A;  4XT7 A;  2HXV A;  3FQZ A;  1S3V A;  5FDA A;  1RX3 A;  4KYA A;  5ECC A;  2DHF A;  1U70 A;  4RGC A;  3KJS A;  3IRN A;  4KY4 A;  3E0B A;  2W9G A;  3FS6 A;  3QYL A;  4FHB A;  5CC9 A;  4P66 A;  5JG0 X;  4GH8 A;  3CSE A;  3KY8 A;  3DAU A;  4Q6A A;  1PD9 A;  5HT5 A;  2OIP A;  1RX6 A;  3JWM A;  4KD7 A;  4KAK A;  3JSU A;  3QFX A;  3GYF A;  1DR7 A;  3DGA A;  3EEJ A;  4KEB A;  3RO9 A;  2LF1 A;  4KM2 A;  3JW5 A;  4QLG A;  1HFR A;  1DAJ A;  5HT4 A;  3SH2 A;  1SEJ A;  4FGG A;  3IA5 A;  4OR7 A;  1KMS A;  4PST A;  3FQO A;  3QL0 A;  3ZPG A;  2CIG A;  3INV A;  3I3R A;  4IXF X;  4Q0E A;  1RB2 A;  1KLK A;  2FZJ A;  3NXX A;  1DLS A;  3NXO A;  4DDR A;  1RA9 A;  3NXY A;  2KGK A;  3FQC A;  3TQA A;  1DRB A;  4I1N A;  1RX9 A;  4G3M A;  5HUI A;  3DG8 A;  3QLY A;  1MVS A;  2C2T A;  2ANO A;  5HF2 X;  3SRS X;  4EJ1 A;  4M6K A;  3K45 A;  1DR2 A;  2JYB A;  3LG4 A;  5HSR A;  2CD2 A;  3NXT A;  3GHC A;  4DPD A;  2O7P A;  4QLE A;  3FQ0 A;  3NZD A;  3QLW A;  4QHV A;  3SRW X;  3EEM A;  2QK8 A;  3K47 A;  4KFJ A;  1J3J A;  1RX1 A;  4PSY A;  5HSU A;  1IA1 A;  4NX7 A;  2B3Z A;  3NZB X;  5U27 A;  3JWF A;  3F8Z A;  1AI9 A;  3FY9 X;  3SQY X;  3CLB A;  3EX8 A;  3JWK A;  4EIG A;  5EAJ A;  1J3I A;  1RX5 A;  4PTJ A;  5HF0 X;  4KNE A;  3IRM A;  3F91 A;  1DHJ A;  2W3A A;  3F8Y A;  1RA8 A;  3QG2 A;  4LEK X;  4HOF A;  3CD2 A;  3QGT A;  1M78 A;  4XT6 A;  2W9H A;  1HFQ A;  3DAT A;  1AO8 A;  3NZ9 X;  1AOE A;  3DFR A;  4X5F A;  3EEL A;  1LY3 A;  3FRB X;  1OHK A;  3GHV A;  1DR4 A;  3EIG A;  2W9S A;  3JW3 A;  4QI9 A;  3FQV A;  1RE7 A;  3FRF X;  3NU0 A;  3KGY A;  3NTZ A;  3S9U A;  3ZPC A;  4IXE D;  4KL9 A;  3K74 A;  4KJJ A;  4M2X A;  4ELG A;  3I8A X;  4PTH A;  5CCC A;  3K2H A;  3TQB A;  2H2Q A;  4XEC X;  2W3B A;  3SR5 X;  3KJR A;  3QLZ A;  1DHF A;  3OCH A;  3VCO A;  3M09 A;  1DRF A;  1YHO A;  3EEK A;  3S7A A;  4DFR A;  2AZN A;  4HA9 A;  4NX6 A;  3FRD X;  1E26 A;  4PSS A;  3F0V X;  2W3M A;  3M08 A;  1JOL A;  4CD2 A;  2BLB A;  3NRR A;  4PDJ A;  1JOM A;  4DPH A;  5ECX A;  5HPB A;  3F0X X;  1RC4 A;  1DRE A;  1J3K A;  4ELB A;  3IRO A;  1JUV A;  1DLR A;  1RG7 A;  4KJK A;  4XRB A;  3FYV X;  4Q67 A;  1M7A A;  4ELE A;  1RB3 A;  2HM9 A;  3SA2 A;  3F0B X;  3QLS A;  1LUD A;  1RX8 A;  1S3U A;  5JA3 A;  1DR6 A;  3CL9 A;  1BZF A;  1DIS A;  1DR5 A;  1DG5 A;  3NZC X;  4M6L A;  2L28 A;  4HOG A;  3HBB A;  3DRC A;  2ZZA A;  4KBN A;  1DDR A;  4ECK A;  3F0S X;  4KM0 A;  1DYJ A;  2INQ A;  4KY8 A;  1DRA A;  3SA1 A;  4DP3 A;  3SRR X;  3NZA X;  1RA1 A;  1RA3 A;  2BLC A;  1VJ3 A;  3FYW X;  1RX2 A;  2FZH A;  4X5G A;  3TD8 A;  1RH3 A;  2W3V A;  2D0K A;  2W9T A;  1D1G A;  4QLF A;  4LAE X;  3GI2 A;  3UM5 A;  5U26 A;  3R33 A;  1DHI A;  4KJL A;  3FL8 A;  3FRA X;  3FY8 X;  1VDR A;  3SRU X;  3D80 A;  3L3R A;  1IA4 A;  3SRQ X;  5E8Q A;  1OHJ A;  4HOE A;  3QLX A;  3ROA A;  1QZF A;  3NXR A;  3DL5 A;  4X5I A;  1DYI A;  5DFR A;  1U71 A;  1IA3 A;  1DG7 A;  4G8Z X;  3NXV A;  4IXG X;  3QYO A;  6DFR A;  2C2S A;  5HI6 A;  4OSG A;  4FGH A;  2BL9 A;  3N0H A;  2ANQ A;  4P3R A;  1S3Y A;  3TQ9 A;  1S3W A;  1DR3 A;  2ITH A;  4ELF A;  1KMV A;  1RD7 A;  3IA4 A;  1DIU A;  4XT5 A;  1DF7 A;  3SAI A;  3FL9 A;  3NZ6 X;  3IX9 A;  4Q0D A;  1ZDR A;  1BOZ A;  4M7V A;  7DFR A;  8DFR A;  5HQY A;  1RF7 A;  4QJZ D;  3Q1H A;  3FRE X;  2BLA A;  1M79 A;  3D84 X;  4LAG X;  3QL3 A;  4TU5 X;  2P4G A;  1HFP A;  1RA2 A;  2D5N A;  2OBC A;  3GHW A;  3UM8 A;  3JWC A;  4XT8 A;  2DRC A;  4ELH A;  5HQZ A;  3RG9 A;  1DYR A;  3DL6 A;  3UM6 A;  3F0U X;  2G6V A;  5HVE A;  1U72 A;  2GD9 A;  3QLR A;  1CD2 A;  4G95 A;  3TQ8 A;  4H98 A;  4P3Q A;  4P68 A;  1DR1 A;  4X5H A;  4M7U A;  4EIZ A;  3JTW A;  2HQP A;  1DG8 A;  1DRH A;  1RX4 A;  2W3W A;  2XW7 A;  3F0Q X;  1RX7 A;  1IA2 A;  1PDB A;  4M6J A;  2FZI A;  4I13 A;  4QJC A;  3S3V A;  4LAH X;  4EIL A;  1TDR A;  1MVT A;  4XE6 X;  3OAF A;  4XT4 A;  4H95 A;  5HVB A;  5DXV A;  1PD8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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