4M6LA

Crystal structure of human dihydrofolate reductase (dhfr) bound to nadp+ and 5,10-dideazatetrahydrofolic acid
Total Genus 53
2040608010012014016018001020304050
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
186
structure length
186
Chain Sequence
VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS1 (4-10)AH4 (118-126)S2 (15-17)TI1 (11-14)TI'1 (18-21)TIV1 (17-20)TIV8 (171-174)AH1 (28-39)S7 (131-138)TII4 (162-165)S3 (47-53)TII2 (67-70)TVIII1 (41-44)TI3 (103-106)TII1 (43-46)S6 (109-114)TI4 (105-108)AH2 (54-59)TIV2 (64-67)3H1 (62-64)S4 (71-75)S5 (88-90)TIV3 (76-79)TII3 (83-86)AH3 (93-101)TI2 (102-105)S8 (146-147)TI5 (153-156)TIV6 (152-155)TIV7 (159-162)S9 (157-159)S10 (170-172)S11 (175-184)Updating...
connected with : NaN
publication title Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Homo sapiens
molecule keywords Dihydrofolate reductase
total genus 53
structure length 186
sequence length 186
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2013-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4m6lA00
3NXVA 2GD9A 1RX7A 3GHCA 1DHFA 4ELHA 3NXYA 4DDRA 4PSTA 1AOEA 1RE7A 2W9TA 2C2TA 4PDJA 2ITHA 7DFRA 1ZDRA 4PTHA 1DR6A 4P66A 4Q0DA 4KY4A 1MVSA 3JSUA 3QLSA 5DFRA 3JWCA 5HI6A 3CL9A 1KMVA 1RX6A 3QLRA 1OHKA 4X5IA 2INQA 1DYJA 3UM5A 1DHIA 2BL9A 3EELA 5HQZA 3IA4A 4G8ZX 3SH2A 3I3RA 3IRMA 1DR2A 1M79A 1DF7A 4XE6X 3UM6A 4G3MA 1DISA 1HFPA 2D5NA 4X5HA 4QLFA 4PSSA 3SRRX 5JG0X 3S3VA 4HA7A 3SR5X 3DRCA 3FRAX 4OSGA 4LAGX 4KFJA 2ZZAA 3N0HA 4FGHA 5ECXA 3SAIA 3QYOA 3QLXA 4HOGA 4KJKA 3JTWA 5FDAA 1VDRA 3FQFA 3JVXA 3NZ6X 1DR3A 2FZJA 4XT4A 4ECKA 3SRSX 3F0SX 1DR4A 1DG8A 3VCOA 3F0VX 4FHBA 1DYHA 4NX6A 3JW3A 4LAEX 3NXRA 2DRCA 4ELBA 3DGAA 3SA2A 2W3WA 1IA2A 3EX8A 4PTJA 4KM2A 4H95A 3S9UA 4KJLA 1RA9A 4XECX 1S3WA 1LY4A 1RH3A 3NZ9X 1S3YA 1CZ3A 4XT5A 3SA1A 6DFRA 3SGYA 2W9HA 3F8YA 3RO9A 3FQOA 3JW5A 4I1NA 1DLSA 1IA4A 4PSYA 4Q0EA 1QZFA 3K74A 1DG5A 1J3JA 1RX3A 4QHVA 4QI9A 5CCCA 3GHVA 5U27A 3KY8A 5HSUA 4M7UA 4DFRA 1U72A 2QK8A 3NXTA 1JOLA 3QLYA 3F0XX 4IXFX 3HJ3A 3E0BA 4KNEA 3IA5A 1JUVA 3KFYA 4KLXA 3GHWA 4EIZA 3IX9A 3KJRA 3S7AA 2CIGA 4HA9A 3EIGA 3JWKA 3F0QX 4P3RA 3QFXA 3TD8A 2G6VA 3FRDX 1DYRA 3QLZA 2CD2A 1DYIA 3IRNA 3QYLA 3QLWA 3RG9A 1KMSA 3GI2A 3EEKA 4LAHX 3OCHA 1VJ3A 3D84X 2KGKA 2FZIA 3CD2A 1KLKA 2H2QA 3F8ZA 3TQ8A 2LF1A 3I8AX 1RB3A 3OAFA 3Q1HA 4KBNA 4ELFA 1DDRA 1DDSA 1RB2A 2W3MA 3IROA 3INVA 2AZNA 3DATA 1DRAA 4KEBA 3KGYA 4IXED 2L28A 1RA8A 3F91A 4DPHA 3DL5A 1SEJA 2ANOA 4KYAA 3FRBX 1S3VA 3EEMA 4M6LA 4KL9A 5HVBA 3R33A 5HF2X 5HT4A 3FS6A 4P3QA 1DREA 3NTZA 3ZPGA 5DXVA 4EILA 1D1GA 4H98A 2D0KA 1DIUA 1LUDA 4TU5X 4Q67A 2W3VA 3KJSA 2W3AA 3NZCX 3D80A 1J3KA 3TQ9A 1HFQA 4HOFA 5ECCA 1RF7A 2BLAA 4XT8A 4QJCA 4ELEA 1RX8A 3FY8X 1LY3A 1DAJA 1J3IA 1IA1A 3JWMA 2JYBA 3F0UX 4XT6A 2W9GA 4OR7A 1E26A 5HPBA 4H97A 1YHOA 4M6JA 4I13A 4NX7A 1PD8A 3QL3A 1TDRA 2BLBA 1DRBA 2OIPA 1RX2A 4KM0A 3EEJA 1DR7A 4QLEA 2C2SA 3FRFX 4FGGA 4HOEA 2P4GA 1RX4A 1OHJA 3M08A 3QG2A 1DHJA 3FYVX 1DG7A 3DFRA 8DFRA 3UM8A 1DRFA 1PDBA 4QJZD 1M7AA 3FQCA 1BOZA 4XT7A 3JWFA 4KJJA 1U71A 2HQPA 4G95A 1RD7A 5HF0X 4LEKX 5CC9A 1RC4A 5HQYA 1MVTA 4EIGA 3HBBA 1DR5A 1RG7A 3DG8A 3M09A 3TQAA 1RX5A 2XW7A 1RA2A 1RX1A 3DL6A 4RGCA 4M7VA 3K47A 3LG4A 1CD2A 3NXXA 4DP3A 3NRRA 4KAKA 3QL0A 3FYWX 3K2HA 3FQVA 3FL8A 2B3ZA 3NZAX 4H96A 3SQYX 4X5JA 2O7PA 2ANQA 3SRWX 1DRHA 4IXGX 2OBCA 4M6KA 1IA3A 4X5GA 3SRUX 5HVEA 1PD9A 1U70A 3ZPCA 4X5FA 3CSEA 5HT5A 3FQ0A 3L3RA 1RA1A 1HFRA 2BLCA 3K45A 1AI9A 4QLGA 1JOMA 3FL9A 4GH8A 2HM9A 1BZFA 4M2XA 1M78A 1RA3A 5E8QA 1DLRA 3DAUA 4ELGA 4DPDA 3QGTA 3TQBA 1RX9A 3GYFA 2HXVA 3FREX 4KD7A 1S3UA 4KY8A 4XRBA 3NZBX 3F0BX 3SRQX 4P68A 3NU0A 3ROAA 1AO8A 3FQZA 5U26A 2W3BA 2FZHA 5HUIA 3NZDA 4Q6AA 4EJ1A 1DR1A 5HSRA 3FY9X 3NXOA 2DHFA 5JA3A 4CD2A 5EAJA 3CLBA 2W9SA
chains in the Genus database with same CATH superfamily
3NXVA 2GD9A 1RX7A 3GHCA 1DHFA 4ELHA 3NXYA 4DDRA 4PSTA 1AOEA 1RE7A 2W9TA 2C2TA 4PDJA 2ITHA 7DFRA 1ZDRA 4PTHA 1DR6A 4P66A 4Q0DA 4KY4A 1MVSA 3JSUA 3QLSA 5DFRA 3JWCA 5HI6A 3CL9A 1KMVA 1RX6A 3QLRA 1OHKA 4X5IA 2INQA 1DYJA 3UM5A 1DHIA 2BL9A 3EELA 5HQZA 3IA4A 4G8ZX 3SH2A 3I3RA 3IRMA 1DR2A 1M79A 1DF7A 4XE6X 3UM6A 4G3MA 1DISA 1HFPA 2D5NA 4X5HA 4QLFA 4PSSA 3SRRX 5JG0X 3S3VA 4HA7A 3SR5X 3DRCA 3FRAX 4OSGA 4LAGX 4KFJA 2ZZAA 3N0HA 4FGHA 5ECXA 3SAIA 3QYOA 3QLXA 4HOGA 4KJKA 3JTWA 5FDAA 1VDRA 3FQFA 3JVXA 3NZ6X 1DR3A 2FZJA 4XT4A 4ECKA 3SRSX 3F0SX 1DR4A 1DG8A 3VCOA 3F0VX 4FHBA 1DYHA 4NX6A 3JW3A 4LAEX 3NXRA 2DRCA 4ELBA 3DGAA 3SA2A 2W3WA 1IA2A 3EX8A 4PTJA 4KM2A 4H95A 3S9UA 4KJLA 1RA9A 4XECX 1S3WA 1LY4A 1RH3A 3NZ9X 1S3YA 1CZ3A 4XT5A 3SA1A 6DFRA 3SGYA 2W9HA 3F8YA 3RO9A 3FQOA 3JW5A 4I1NA 1DLSA 1IA4A 4PSYA 4Q0EA 1QZFA 3K74A 1DG5A 1J3JA 1RX3A 4QHVA 4QI9A 5CCCA 3GHVA 5U27A 3KY8A 5HSUA 4M7UA 4DFRA 1U72A 2QK8A 3NXTA 1JOLA 3QLYA 3F0XX 4IXFX 3HJ3A 3E0BA 4KNEA 3IA5A 1JUVA 3KFYA 4KLXA 3GHWA 4EIZA 3IX9A 3KJRA 3S7AA 2CIGA 4HA9A 3EIGA 3JWKA 3F0QX 4P3RA 3QFXA 3TD8A 2G6VA 3FRDX 1DYRA 3QLZA 2CD2A 1DYIA 3IRNA 3QYLA 3QLWA 3RG9A 1KMSA 3GI2A 3EEKA 4LAHX 3OCHA 1VJ3A 3D84X 2KGKA 2FZIA 3CD2A 1KLKA 2H2QA 3F8ZA 3TQ8A 2LF1A 3I8AX 1RB3A 3OAFA 3Q1HA 4KBNA 4ELFA 1DDRA 1DDSA 1RB2A 2W3MA 3IROA 3INVA 2AZNA 3DATA 1DRAA 4KEBA 3KGYA 4IXED 2L28A 1RA8A 3F91A 4DPHA 3DL5A 1SEJA 2ANOA 4KYAA 3FRBX 1S3VA 3EEMA 4M6LA 4KL9A 5HVBA 3R33A 5HF2X 5HT4A 3FS6A 4P3QA 1DREA 3NTZA 3ZPGA 5DXVA 4EILA 1D1GA 4H98A 2D0KA 1DIUA 1LUDA 4TU5X 4Q67A 2W3VA 3KJSA 2W3AA 3NZCX 3D80A 1J3KA 3TQ9A 1HFQA 4HOFA 5ECCA 1RF7A 2BLAA 4XT8A 4QJCA 4ELEA 1RX8A 3FY8X 1LY3A 1DAJA 1J3IA 1IA1A 3JWMA 2JYBA 3F0UX 4XT6A 2W9GA 4OR7A 1E26A 5HPBA 4H97A 1YHOA 4M6JA 4I13A 4NX7A 1PD8A 3QL3A 1TDRA 2BLBA 1DRBA 2OIPA 1RX2A 4KM0A 3EEJA 1DR7A 4QLEA 2C2SA 3FRFX 4FGGA 4HOEA 2P4GA 1RX4A 1OHJA 3M08A 3QG2A 1DHJA 3FYVX 1DG7A 3DFRA 8DFRA 3UM8A 1DRFA 1PDBA 4QJZD 1M7AA 3FQCA 1BOZA 4XT7A 3JWFA 4KJJA 1U71A 2HQPA 4G95A 1RD7A 5HF0X 4LEKX 5CC9A 1RC4A 5HQYA 1MVTA 4EIGA 3HBBA 1DR5A 1RG7A 3DG8A 3M09A 3TQAA 1RX5A 2XW7A 1RA2A 1RX1A 3DL6A 4RGCA 4M7VA 3K47A 3LG4A 1CD2A 3NXXA 4DP3A 3NRRA 4KAKA 3QL0A 3FYWX 3K2HA 3FQVA 3FL8A 2B3ZA 3NZAX 4H96A 3SQYX 4X5JA 2O7PA 2ANQA 3SRWX 1DRHA 4IXGX 2OBCA 4M6KA 1IA3A 4X5GA 3SRUX 5HVEA 1PD9A 1U70A 3ZPCA 4X5FA 3CSEA 5HT5A 3FQ0A 3L3RA 1RA1A 1HFRA 2BLCA 3K45A 1AI9A 4QLGA 1JOMA 3FL9A 4GH8A 2HM9A 1BZFA 4M2XA 1M78A 1RA3A 5E8QA 1DLRA 3DAUA 4ELGA 4DPDA 3QGTA 3TQBA 1RX9A 3GYFA 2HXVA 3FREX 4KD7A 1S3UA 4KY8A 4XRBA 3NZBX 3F0BX 3SRQX 4P68A 3NU0A 3ROAA 1AO8A 3FQZA 5U26A 2W3BA 2FZHA 5HUIA 3NZDA 4Q6AA 4EJ1A 1DR1A 5HSRA 3FY9X 3NXOA 2DHFA 5JA3A 4CD2A 5EAJA 3CLBA 2W9SA
chains in the Genus database with same CATH topology
3NXVA 2GD9A 1RX7A 3GHCA 1DHFA 4ELHA 3NXYA 4DDRA 4PSTA 1AOEA 1RE7A 2W9TA 2C2TA 4PDJA 2ITHA 7DFRA 1ZDRA 4PTHA 1DR6A 4P66A 4Q0DA 4KY4A 1MVSA 3JSUA 3QLSA 5DFRA 3JWCA 5HI6A 3CL9A 1KMVA 1RX6A 3QLRA 1OHKA 4X5IA 2INQA 1DYJA 3UM5A 1DHIA 2BL9A 3EELA 5HQZA 3IA4A 4G8ZX 3SH2A 3I3RA 3IRMA 1DR2A 1M79A 1DF7A 4XE6X 3UM6A 4G3MA 1DISA 1HFPA 2D5NA 4X5HA 4QLFA 4PSSA 3SRRX 5JG0X 3S3VA 4HA7A 3SR5X 3DRCA 3FRAX 4OSGA 4LAGX 4KFJA 2ZZAA 3N0HA 4FGHA 5ECXA 3SAIA 3QYOA 3QLXA 4HOGA 4KJKA 3JTWA 5FDAA 1VDRA 3FQFA 3JVXA 3NZ6X 1DR3A 2FZJA 4XT4A 4ECKA 3SRSX 3F0SX 1DR4A 1DG8A 3VCOA 3F0VX 4FHBA 1DYHA 4NX6A 3JW3A 4LAEX 3NXRA 2DRCA 4ELBA 3DGAA 3SA2A 2W3WA 1IA2A 3EX8A 4PTJA 4KM2A 4H95A 3S9UA 4KJLA 1RA9A 4XECX 1S3WA 1LY4A 1RH3A 3NZ9X 1S3YA 1CZ3A 4XT5A 3SA1A 6DFRA 3SGYA 2W9HA 3F8YA 3RO9A 3FQOA 3JW5A 4I1NA 1DLSA 1IA4A 4PSYA 4Q0EA 1QZFA 3K74A 1DG5A 1J3JA 1RX3A 4QHVA 4QI9A 5CCCA 3GHVA 5U27A 3KY8A 5HSUA 4M7UA 4DFRA 1U72A 2QK8A 3NXTA 1JOLA 3QLYA 3F0XX 4IXFX 3HJ3A 3E0BA 4KNEA 3IA5A 1JUVA 3KFYA 4KLXA 3GHWA 4EIZA 3IX9A 3KJRA 3S7AA 2CIGA 4HA9A 3EIGA 3JWKA 3F0QX 4P3RA 3QFXA 3TD8A 2G6VA 3FRDX 1DYRA 3QLZA 2CD2A 1DYIA 3IRNA 3QYLA 3QLWA 3RG9A 1KMSA 3GI2A 3EEKA 4LAHX 3OCHA 1VJ3A 3D84X 2KGKA 2FZIA 3CD2A 1KLKA 2H2QA 3F8ZA 3TQ8A 2LF1A 3I8AX 1RB3A 3OAFA 3Q1HA 4KBNA 4ELFA 1DDRA 1DDSA 1RB2A 2W3MA 3IROA 3INVA 2AZNA 3DATA 1DRAA 4KEBA 3KGYA 4IXED 2L28A 1RA8A 3F91A 4DPHA 3DL5A 1SEJA 2ANOA 4KYAA 3FRBX 1S3VA 3EEMA 4M6LA 4KL9A 5HVBA 3R33A 5HF2X 5HT4A 3FS6A 4P3QA 1DREA 3NTZA 3ZPGA 5DXVA 4EILA 1D1GA 4H98A 2D0KA 1DIUA 1LUDA 4TU5X 4Q67A 2W3VA 3KJSA 2W3AA 3NZCX 3D80A 1J3KA 3TQ9A 1HFQA 4HOFA 5ECCA 1RF7A 2BLAA 4XT8A 4QJCA 4ELEA 1RX8A 3FY8X 1LY3A 1DAJA 1J3IA 1IA1A 3JWMA 2JYBA 3F0UX 4XT6A 2W9GA 4OR7A 1E26A 5HPBA 4H97A 1YHOA 4M6JA 4I13A 4NX7A 1PD8A 3QL3A 1TDRA 2BLBA 1DRBA 2OIPA 1RX2A 4KM0A 3EEJA 1DR7A 4QLEA 2C2SA 3FRFX 4FGGA 4HOEA 2P4GA 1RX4A 1OHJA 3M08A 3QG2A 1DHJA 3FYVX 1DG7A 3DFRA 8DFRA 3UM8A 1DRFA 1PDBA 4QJZD 1M7AA 3FQCA 1BOZA 4XT7A 3JWFA 4KJJA 1U71A 2HQPA 4G95A 1RD7A 5HF0X 4LEKX 5CC9A 1RC4A 5HQYA 1MVTA 4EIGA 3HBBA 1DR5A 1RG7A 3DG8A 3M09A 3TQAA 1RX5A 2XW7A 1RA2A 1RX1A 3DL6A 4RGCA 4M7VA 3K47A 3LG4A 1CD2A 3NXXA 4DP3A 3NRRA 4KAKA 3QL0A 3FYWX 3K2HA 3FQVA 3FL8A 2B3ZA 3NZAX 4H96A 3SQYX 4X5JA 2O7PA 2ANQA 3SRWX 1DRHA 4IXGX 2OBCA 4M6KA 1IA3A 4X5GA 3SRUX 5HVEA 1PD9A 1U70A 3ZPCA 4X5FA 3CSEA 5HT5A 3FQ0A 3L3RA 1RA1A 1HFRA 2BLCA 3K45A 1AI9A 4QLGA 1JOMA 3FL9A 4GH8A 2HM9A 1BZFA 4M2XA 1M78A 1RA3A 5E8QA 1DLRA 3DAUA 4ELGA 4DPDA 3QGTA 3TQBA 1RX9A 3GYFA 2HXVA 3FREX 4KD7A 1S3UA 4KY8A 4XRBA 3NZBX 3F0BX 3SRQX 4P68A 3NU0A 3ROAA 1AO8A 3FQZA 5U26A 2W3BA 2FZHA 5HUIA 3NZDA 4Q6AA 4EJ1A 1DR1A 5HSRA 3FY9X 3NXOA 2DHFA 5JA3A 4CD2A 5EAJA 3CLBA 2W9SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NXV A;  2GD9 A;  1RX7 A;  3GHC A;  1DHF A;  4ELH A;  3NXY A;  4DDR A;  4PST A;  1AOE A;  1RE7 A;  2W9T A;  2C2T A;  4PDJ A;  2ITH A;  7DFR A;  1ZDR A;  4PTH A;  1DR6 A;  4P66 A;  4Q0D A;  4KY4 A;  1MVS A;  3JSU A;  3QLS A;  5DFR A;  3JWC A;  5HI6 A;  3CL9 A;  1KMV A;  1RX6 A;  3QLR A;  1OHK A;  4X5I A;  2INQ A;  1DYJ A;  3UM5 A;  1DHI A;  2BL9 A;  3EEL A;  5HQZ A;  3IA4 A;  4G8Z X;  3SH2 A;  3I3R A;  3IRM A;  1DR2 A;  1M79 A;  1DF7 A;  4XE6 X;  3UM6 A;  4G3M A;  1DIS A;  1HFP A;  2D5N A;  4X5H A;  4QLF A;  4PSS A;  3SRR X;  5JG0 X;  3S3V A;  4HA7 A;  3SR5 X;  3DRC A;  3FRA X;  4OSG A;  4LAG X;  4KFJ A;  2ZZA A;  3N0H A;  4FGH A;  5ECX A;  3SAI A;  3QYO A;  3QLX A;  4HOG A;  4KJK A;  3JTW A;  5FDA A;  1VDR A;  3FQF A;  3JVX A;  3NZ6 X;  1DR3 A;  2FZJ A;  4XT4 A;  4ECK A;  3SRS X;  3F0S X;  1DR4 A;  1DG8 A;  3VCO A;  3F0V X;  4FHB A;  1DYH A;  4NX6 A;  3JW3 A;  4LAE X;  3NXR A;  2DRC A;  4ELB A;  3DGA A;  3SA2 A;  2W3W A;  1IA2 A;  3EX8 A;  4PTJ A;  4KM2 A;  4H95 A;  3S9U A;  4KJL A;  1RA9 A;  4XEC X;  1S3W A;  1LY4 A;  1RH3 A;  3NZ9 X;  1S3Y A;  1CZ3 A;  4XT5 A;  3SA1 A;  6DFR A;  3SGY A;  2W9H A;  3F8Y A;  3RO9 A;  3FQO A;  3JW5 A;  4I1N A;  1DLS A;  1IA4 A;  4PSY A;  4Q0E A;  1QZF A;  3K74 A;  1DG5 A;  1J3J A;  1RX3 A;  4QHV A;  4QI9 A;  5CCC A;  3GHV A;  5U27 A;  3KY8 A;  5HSU A;  4M7U A;  4DFR A;  1U72 A;  2QK8 A;  3NXT A;  1JOL A;  3QLY A;  3F0X X;  4IXF X;  3HJ3 A;  3E0B A;  4KNE A;  3IA5 A;  1JUV A;  3KFY A;  4KLX A;  3GHW A;  4EIZ A;  3IX9 A;  3KJR A;  3S7A A;  2CIG A;  4HA9 A;  3EIG A;  3JWK A;  3F0Q X;  4P3R A;  3QFX A;  3TD8 A;  2G6V A;  3FRD X;  1DYR A;  3QLZ A;  2CD2 A;  1DYI A;  3IRN A;  3QYL A;  3QLW A;  3RG9 A;  1KMS A;  3GI2 A;  3EEK A;  4LAH X;  3OCH A;  1VJ3 A;  3D84 X;  2KGK A;  2FZI A;  3CD2 A;  1KLK A;  2H2Q A;  3F8Z A;  3TQ8 A;  2LF1 A;  3I8A X;  1RB3 A;  3OAF A;  3Q1H A;  4KBN A;  4ELF A;  1DDR A;  1DDS A;  1RB2 A;  2W3M A;  3IRO A;  3INV A;  2AZN A;  3DAT A;  1DRA A;  4KEB A;  3KGY A;  4IXE D;  2L28 A;  1RA8 A;  3F91 A;  4DPH A;  3DL5 A;  1SEJ A;  2ANO A;  4KYA A;  3FRB X;  1S3V A;  3EEM A;  4M6L A;  4KL9 A;  5HVB A;  3R33 A;  5HF2 X;  5HT4 A;  3FS6 A;  4P3Q A;  1DRE A;  3NTZ A;  3ZPG A;  5DXV A;  4EIL A;  1D1G A;  4H98 A;  2D0K A;  1DIU A;  1LUD A;  4TU5 X;  4Q67 A;  2W3V A;  3KJS A;  2W3A A;  3NZC X;  3D80 A;  1J3K A;  3TQ9 A;  1HFQ A;  4HOF A;  5ECC A;  1RF7 A;  2BLA A;  4XT8 A;  4QJC A;  4ELE A;  1RX8 A;  3FY8 X;  1LY3 A;  1DAJ A;  1J3I A;  1IA1 A;  3JWM A;  2JYB A;  3F0U X;  4XT6 A;  2W9G A;  4OR7 A;  1E26 A;  5HPB A;  4H97 A;  1YHO A;  4M6J A;  4I13 A;  4NX7 A;  1PD8 A;  3QL3 A;  1TDR A;  2BLB A;  1DRB A;  2OIP A;  1RX2 A;  4KM0 A;  3EEJ A;  1DR7 A;  4QLE A;  2C2S A;  3FRF X;  4FGG A;  4HOE A;  2P4G A;  1RX4 A;  1OHJ A;  3M08 A;  3QG2 A;  1DHJ A;  3FYV X;  1DG7 A;  3DFR A;  8DFR A;  3UM8 A;  1DRF A;  1PDB A;  4QJZ D;  1M7A A;  3FQC A;  1BOZ A;  4XT7 A;  3JWF A;  4KJJ A;  1U71 A;  2HQP A;  4G95 A;  1RD7 A;  5HF0 X;  4LEK X;  5CC9 A;  1RC4 A;  5HQY A;  1MVT A;  4EIG A;  3HBB A;  1DR5 A;  1RG7 A;  3DG8 A;  3M09 A;  3TQA A;  1RX5 A;  2XW7 A;  1RA2 A;  1RX1 A;  3DL6 A;  4RGC A;  4M7V A;  3K47 A;  3LG4 A;  1CD2 A;  3NXX A;  4DP3 A;  3NRR A;  4KAK A;  3QL0 A;  3FYW X;  3K2H A;  3FQV A;  3FL8 A;  2B3Z A;  3NZA X;  4H96 A;  3SQY X;  4X5J A;  2O7P A;  2ANQ A;  3SRW X;  1DRH A;  4IXG X;  2OBC A;  4M6K A;  1IA3 A;  4X5G A;  3SRU X;  5HVE A;  1PD9 A;  1U70 A;  3ZPC A;  4X5F A;  3CSE A;  5HT5 A;  3FQ0 A;  3L3R A;  1RA1 A;  1HFR A;  2BLC A;  3K45 A;  1AI9 A;  4QLG A;  1JOM A;  3FL9 A;  4GH8 A;  2HM9 A;  1BZF A;  4M2X A;  1M78 A;  1RA3 A;  5E8Q A;  1DLR A;  3DAU A;  4ELG A;  4DPD A;  3QGT A;  3TQB A;  1RX9 A;  3GYF A;  2HXV A;  3FRE X;  4KD7 A;  1S3U A;  4KY8 A;  4XRB A;  3NZB X;  3F0B X;  3SRQ X;  4P68 A;  3NU0 A;  3ROA A;  1AO8 A;  3FQZ A;  5U26 A;  2W3B A;  2FZH A;  5HUI A;  3NZD A;  4Q6A A;  4EJ1 A;  1DR1 A;  5HSR A;  3FY9 X;  3NXO A;  2DHF A;  5JA3 A;  4CD2 A;  5EAJ A;  3CLB A;  2W9S A; 
#chains in the Genus database with same CATH topology
 3NXV A;  2GD9 A;  1RX7 A;  3GHC A;  1DHF A;  4ELH A;  3NXY A;  4DDR A;  4PST A;  1AOE A;  1RE7 A;  2W9T A;  2C2T A;  4PDJ A;  2ITH A;  7DFR A;  1ZDR A;  4PTH A;  1DR6 A;  4P66 A;  4Q0D A;  4KY4 A;  1MVS A;  3JSU A;  3QLS A;  5DFR A;  3JWC A;  5HI6 A;  3CL9 A;  1KMV A;  1RX6 A;  3QLR A;  1OHK A;  4X5I A;  2INQ A;  1DYJ A;  3UM5 A;  1DHI A;  2BL9 A;  3EEL A;  5HQZ A;  3IA4 A;  4G8Z X;  3SH2 A;  3I3R A;  3IRM A;  1DR2 A;  1M79 A;  1DF7 A;  4XE6 X;  3UM6 A;  4G3M A;  1DIS A;  1HFP A;  2D5N A;  4X5H A;  4QLF A;  4PSS A;  3SRR X;  5JG0 X;  3S3V A;  4HA7 A;  3SR5 X;  3DRC A;  3FRA X;  4OSG A;  4LAG X;  4KFJ A;  2ZZA A;  3N0H A;  4FGH A;  5ECX A;  3SAI A;  3QYO A;  3QLX A;  4HOG A;  4KJK A;  3JTW A;  5FDA A;  1VDR A;  3FQF A;  3JVX A;  3NZ6 X;  1DR3 A;  2FZJ A;  4XT4 A;  4ECK A;  3SRS X;  3F0S X;  1DR4 A;  1DG8 A;  3VCO A;  3F0V X;  4FHB A;  1DYH A;  4NX6 A;  3JW3 A;  4LAE X;  3NXR A;  2DRC A;  4ELB A;  3DGA A;  3SA2 A;  2W3W A;  1IA2 A;  3EX8 A;  4PTJ A;  4KM2 A;  4H95 A;  3S9U A;  4KJL A;  1RA9 A;  4XEC X;  1S3W A;  1LY4 A;  1RH3 A;  3NZ9 X;  1S3Y A;  1CZ3 A;  4XT5 A;  3SA1 A;  6DFR A;  3SGY A;  2W9H A;  3F8Y A;  3RO9 A;  3FQO A;  3JW5 A;  4I1N A;  1DLS A;  1IA4 A;  4PSY A;  4Q0E A;  1QZF A;  3K74 A;  1DG5 A;  1J3J A;  1RX3 A;  4QHV A;  4QI9 A;  5CCC A;  3GHV A;  5U27 A;  3KY8 A;  5HSU A;  4M7U A;  4DFR A;  1U72 A;  2QK8 A;  3NXT A;  1JOL A;  3QLY A;  3F0X X;  4IXF X;  3HJ3 A;  3E0B A;  4KNE A;  3IA5 A;  1JUV A;  3KFY A;  4KLX A;  3GHW A;  4EIZ A;  3IX9 A;  3KJR A;  3S7A A;  2CIG A;  4HA9 A;  3EIG A;  3JWK A;  3F0Q X;  4P3R A;  3QFX A;  3TD8 A;  2G6V A;  3FRD X;  1DYR A;  3QLZ A;  2CD2 A;  1DYI A;  3IRN A;  3QYL A;  3QLW A;  3RG9 A;  1KMS A;  3GI2 A;  3EEK A;  4LAH X;  3OCH A;  1VJ3 A;  3D84 X;  2KGK A;  2FZI A;  3CD2 A;  1KLK A;  2H2Q A;  3F8Z A;  3TQ8 A;  2LF1 A;  3I8A X;  1RB3 A;  3OAF A;  3Q1H A;  4KBN A;  4ELF A;  1DDR A;  1DDS A;  1RB2 A;  2W3M A;  3IRO A;  3INV A;  2AZN A;  3DAT A;  1DRA A;  4KEB A;  3KGY A;  4IXE D;  2L28 A;  1RA8 A;  3F91 A;  4DPH A;  3DL5 A;  1SEJ A;  2ANO A;  4KYA A;  3FRB X;  1S3V A;  3EEM A;  4M6L A;  4KL9 A;  5HVB A;  3R33 A;  5HF2 X;  5HT4 A;  3FS6 A;  4P3Q A;  1DRE A;  3NTZ A;  3ZPG A;  5DXV A;  4EIL A;  1D1G A;  4H98 A;  2D0K A;  1DIU A;  1LUD A;  4TU5 X;  4Q67 A;  2W3V A;  3KJS A;  2W3A A;  3NZC X;  3D80 A;  1J3K A;  3TQ9 A;  1HFQ A;  4HOF A;  5ECC A;  1RF7 A;  2BLA A;  4XT8 A;  4QJC A;  4ELE A;  1RX8 A;  3FY8 X;  1LY3 A;  1DAJ A;  1J3I A;  1IA1 A;  3JWM A;  2JYB A;  3F0U X;  4XT6 A;  2W9G A;  4OR7 A;  1E26 A;  5HPB A;  4H97 A;  1YHO A;  4M6J A;  4I13 A;  4NX7 A;  1PD8 A;  3QL3 A;  1TDR A;  2BLB A;  1DRB A;  2OIP A;  1RX2 A;  4KM0 A;  3EEJ A;  1DR7 A;  4QLE A;  2C2S A;  3FRF X;  4FGG A;  4HOE A;  2P4G A;  1RX4 A;  1OHJ A;  3M08 A;  3QG2 A;  1DHJ A;  3FYV X;  1DG7 A;  3DFR A;  8DFR A;  3UM8 A;  1DRF A;  1PDB A;  4QJZ D;  1M7A A;  3FQC A;  1BOZ A;  4XT7 A;  3JWF A;  4KJJ A;  1U71 A;  2HQP A;  4G95 A;  1RD7 A;  5HF0 X;  4LEK X;  5CC9 A;  1RC4 A;  5HQY A;  1MVT A;  4EIG A;  3HBB A;  1DR5 A;  1RG7 A;  3DG8 A;  3M09 A;  3TQA A;  1RX5 A;  2XW7 A;  1RA2 A;  1RX1 A;  3DL6 A;  4RGC A;  4M7V A;  3K47 A;  3LG4 A;  1CD2 A;  3NXX A;  4DP3 A;  3NRR A;  4KAK A;  3QL0 A;  3FYW X;  3K2H A;  3FQV A;  3FL8 A;  2B3Z A;  3NZA X;  4H96 A;  3SQY X;  4X5J A;  2O7P A;  2ANQ A;  3SRW X;  1DRH A;  4IXG X;  2OBC A;  4M6K A;  1IA3 A;  4X5G A;  3SRU X;  5HVE A;  1PD9 A;  1U70 A;  3ZPC A;  4X5F A;  3CSE A;  5HT5 A;  3FQ0 A;  3L3R A;  1RA1 A;  1HFR A;  2BLC A;  3K45 A;  1AI9 A;  4QLG A;  1JOM A;  3FL9 A;  4GH8 A;  2HM9 A;  1BZF A;  4M2X A;  1M78 A;  1RA3 A;  5E8Q A;  1DLR A;  3DAU A;  4ELG A;  4DPD A;  3QGT A;  3TQB A;  1RX9 A;  3GYF A;  2HXV A;  3FRE X;  4KD7 A;  1S3U A;  4KY8 A;  4XRB A;  3NZB X;  3F0B X;  3SRQ X;  4P68 A;  3NU0 A;  3ROA A;  1AO8 A;  3FQZ A;  5U26 A;  2W3B A;  2FZH A;  5HUI A;  3NZD A;  4Q6A A;  4EJ1 A;  1DR1 A;  5HSR A;  3FY9 X;  3NXO A;  2DHF A;  5JA3 A;  4CD2 A;  5EAJ A;  3CLB A;  2W9S A; 
#chains in the Genus database with same CATH homology
 3NXV A;  2GD9 A;  1RX7 A;  3GHC A;  1DHF A;  4ELH A;  3NXY A;  4DDR A;  4PST A;  1AOE A;  1RE7 A;  2W9T A;  2C2T A;  4PDJ A;  2ITH A;  7DFR A;  1ZDR A;  4PTH A;  1DR6 A;  4P66 A;  4Q0D A;  4KY4 A;  1MVS A;  3JSU A;  3QLS A;  5DFR A;  3JWC A;  5HI6 A;  3CL9 A;  1KMV A;  1RX6 A;  3QLR A;  1OHK A;  4X5I A;  2INQ A;  1DYJ A;  3UM5 A;  1DHI A;  2BL9 A;  3EEL A;  5HQZ A;  3IA4 A;  4G8Z X;  3SH2 A;  3I3R A;  3IRM A;  1DR2 A;  1M79 A;  1DF7 A;  4XE6 X;  3UM6 A;  4G3M A;  1DIS A;  1HFP A;  2D5N A;  4X5H A;  4QLF A;  4PSS A;  3SRR X;  5JG0 X;  3S3V A;  4HA7 A;  3SR5 X;  3DRC A;  3FRA X;  4OSG A;  4LAG X;  4KFJ A;  2ZZA A;  3N0H A;  4FGH A;  5ECX A;  3SAI A;  3QYO A;  3QLX A;  4HOG A;  4KJK A;  3JTW A;  5FDA A;  1VDR A;  3FQF A;  3JVX A;  3NZ6 X;  1DR3 A;  2FZJ A;  4XT4 A;  4ECK A;  3SRS X;  3F0S X;  1DR4 A;  1DG8 A;  3VCO A;  3F0V X;  4FHB A;  1DYH A;  4NX6 A;  3JW3 A;  4LAE X;  3NXR A;  2DRC A;  4ELB A;  3DGA A;  3SA2 A;  2W3W A;  1IA2 A;  3EX8 A;  4PTJ A;  4KM2 A;  4H95 A;  3S9U A;  4KJL A;  1RA9 A;  4XEC X;  1S3W A;  1LY4 A;  1RH3 A;  3NZ9 X;  1S3Y A;  1CZ3 A;  4XT5 A;  3SA1 A;  6DFR A;  3SGY A;  2W9H A;  3F8Y A;  3RO9 A;  3FQO A;  3JW5 A;  4I1N A;  1DLS A;  1IA4 A;  4PSY A;  4Q0E A;  1QZF A;  3K74 A;  1DG5 A;  1J3J A;  1RX3 A;  4QHV A;  4QI9 A;  5CCC A;  3GHV A;  5U27 A;  3KY8 A;  5HSU A;  4M7U A;  4DFR A;  1U72 A;  2QK8 A;  3NXT A;  1JOL A;  3QLY A;  3F0X X;  4IXF X;  3HJ3 A;  3E0B A;  4KNE A;  3IA5 A;  1JUV A;  3KFY A;  4KLX A;  3GHW A;  4EIZ A;  3IX9 A;  3KJR A;  3S7A A;  2CIG A;  4HA9 A;  3EIG A;  3JWK A;  3F0Q X;  4P3R A;  3QFX A;  3TD8 A;  2G6V A;  3FRD X;  1DYR A;  3QLZ A;  2CD2 A;  1DYI A;  3IRN A;  3QYL A;  3QLW A;  3RG9 A;  1KMS A;  3GI2 A;  3EEK A;  4LAH X;  3OCH A;  1VJ3 A;  3D84 X;  2KGK A;  2FZI A;  3CD2 A;  1KLK A;  2H2Q A;  3F8Z A;  3TQ8 A;  2LF1 A;  3I8A X;  1RB3 A;  3OAF A;  3Q1H A;  4KBN A;  4ELF A;  1DDR A;  1DDS A;  1RB2 A;  2W3M A;  3IRO A;  3INV A;  2AZN A;  3DAT A;  1DRA A;  4KEB A;  3KGY A;  4IXE D;  2L28 A;  1RA8 A;  3F91 A;  4DPH A;  3DL5 A;  1SEJ A;  2ANO A;  4KYA A;  3FRB X;  1S3V A;  3EEM A;  4M6L A;  4KL9 A;  5HVB A;  3R33 A;  5HF2 X;  5HT4 A;  3FS6 A;  4P3Q A;  1DRE A;  3NTZ A;  3ZPG A;  5DXV A;  4EIL A;  1D1G A;  4H98 A;  2D0K A;  1DIU A;  1LUD A;  4TU5 X;  4Q67 A;  2W3V A;  3KJS A;  2W3A A;  3NZC X;  3D80 A;  1J3K A;  3TQ9 A;  1HFQ A;  4HOF A;  5ECC A;  1RF7 A;  2BLA A;  4XT8 A;  4QJC A;  4ELE A;  1RX8 A;  3FY8 X;  1LY3 A;  1DAJ A;  1J3I A;  1IA1 A;  3JWM A;  2JYB A;  3F0U X;  4XT6 A;  2W9G A;  4OR7 A;  1E26 A;  5HPB A;  4H97 A;  1YHO A;  4M6J A;  4I13 A;  4NX7 A;  1PD8 A;  3QL3 A;  1TDR A;  2BLB A;  1DRB A;  2OIP A;  1RX2 A;  4KM0 A;  3EEJ A;  1DR7 A;  4QLE A;  2C2S A;  3FRF X;  4FGG A;  4HOE A;  2P4G A;  1RX4 A;  1OHJ A;  3M08 A;  3QG2 A;  1DHJ A;  3FYV X;  1DG7 A;  3DFR A;  8DFR A;  3UM8 A;  1DRF A;  1PDB A;  4QJZ D;  1M7A A;  3FQC A;  1BOZ A;  4XT7 A;  3JWF A;  4KJJ A;  1U71 A;  2HQP A;  4G95 A;  1RD7 A;  5HF0 X;  4LEK X;  5CC9 A;  1RC4 A;  5HQY A;  1MVT A;  4EIG A;  3HBB A;  1DR5 A;  1RG7 A;  3DG8 A;  3M09 A;  3TQA A;  1RX5 A;  2XW7 A;  1RA2 A;  1RX1 A;  3DL6 A;  4RGC A;  4M7V A;  3K47 A;  3LG4 A;  1CD2 A;  3NXX A;  4DP3 A;  3NRR A;  4KAK A;  3QL0 A;  3FYW X;  3K2H A;  3FQV A;  3FL8 A;  2B3Z A;  3NZA X;  4H96 A;  3SQY X;  4X5J A;  2O7P A;  2ANQ A;  3SRW X;  1DRH A;  4IXG X;  2OBC A;  4M6K A;  1IA3 A;  4X5G A;  3SRU X;  5HVE A;  1PD9 A;  1U70 A;  3ZPC A;  4X5F A;  3CSE A;  5HT5 A;  3FQ0 A;  3L3R A;  1RA1 A;  1HFR A;  2BLC A;  3K45 A;  1AI9 A;  4QLG A;  1JOM A;  3FL9 A;  4GH8 A;  2HM9 A;  1BZF A;  4M2X A;  1M78 A;  1RA3 A;  5E8Q A;  1DLR A;  3DAU A;  4ELG A;  4DPD A;  3QGT A;  3TQB A;  1RX9 A;  3GYF A;  2HXV A;  3FRE X;  4KD7 A;  1S3U A;  4KY8 A;  4XRB A;  3NZB X;  3F0B X;  3SRQ X;  4P68 A;  3NU0 A;  3ROA A;  1AO8 A;  3FQZ A;  5U26 A;  2W3B A;  2FZH A;  5HUI A;  3NZD A;  4Q6A A;  4EJ1 A;  1DR1 A;  5HSR A;  3FY9 X;  3NXO A;  2DHF A;  5JA3 A;  4CD2 A;  5EAJ A;  3CLB A;  2W9S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

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