4PDJA

Neutron crystal structure of e.coli dihydrofolate reductase complexed with folate and nadp+
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Dihydrofolate reductase
total genus 45
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-04-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4pdjA00
2D0KA 1HFRA 3DATA 1RX4A 3FRAX 2C2TA 3GYFA 1VDRA 3NZCX 2OBCA 1MVTA 3VCOA 1DR2A 4QLFA 3JW5A 7DFRA 4PSYA 4XT5A 3NXXA 5CCCA 4IXFX 1BZFA 1DYJA 3KY8A 1HFPA 3FYVX 3SRSX 2BL9A 3F0BX 2W3WA 4PSSA 1DF7A 3TQ8A 5HF2X 2HM9A 4EIGA 2W3MA 3EEKA 4PDJA 1DREA 2LF1A 1LY3A 5HVEA 2BLCA 4CD2A 1RA2A 1BOZA 5HVBA 3FS6A 4DPHA 3KGYA 3IA5A 3IX9A 3K45A 2OIPA 1HFQA 3QLWA 4XT6A 4G3MA 5HQYA 4QLEA 4P3QA 3TQBA 2H2QA 5CC9A 4LAEX 5ECXA 4G95A 4RGCA 1PD9A 2JYBA 2W9GA 4Q0EA 5ECCA 3NZBX 2XW7A 3M09A 1DLRA 3ZPGA 1DIUA 8DFRA 3F8YA 1RX1A 5HI6A 3IROA 1RB3A 1U72A 1RD7A 1AO8A 3D84X 4PTJA 1RB2A 3IRNA 4HOGA 2P4GA 1DR6A 4FGGA 3Q1HA 3SRWX 1E26A 1QZFA 2O7PA 1RE7A 5HSUA 4M2XA 3FYWX 4KY4A 3L3RA 3FRDX 1J3JA 2HXVA 4FHBA 1OHKA 4I1NA 4KJJA 4XECX 4H97A 1RA9A 3JWKA 3LG4A 4LEKX 4KJLA 3DL6A 2HQPA 4KBNA 1ZDRA 3F0VX 2W3BA 3QL3A 1JOMA 4QJCA 3DL5A 4P68A 5HT5A 1DR1A 3NXOA 5HUIA 3QGTA 1DR5A 2AZNA 1RH3A 3M08A 1JOLA 3UM6A 3F8ZA 4KM2A 3TQAA 3K2HA 1DLSA 1IA2A 3INVA 5DFRA 2BLAA 3UM8A 4X5GA 2GD9A 1PDBA 2DHFA 4KJKA 2KGKA 3ROAA 3JWCA 3QLSA 4M6LA 4KLXA 2BLBA 4OSGA 4FGHA 1RX8A 3D80A 3SA1A 4IXGX 3N0HA 5FDAA 1DDRA 3NU0A 2CIGA 4HA7A 1U71A 3K74A 4IXED 3SR5X 5EAJA 1DHIA 4QHVA 1CD2A 1AI9A 2FZHA 1RX9A 3F0UX 3QL0A 2W3VA 3FQCA 5E8QA 4X5JA 4ELBA 4GH8A 3K47A 4X5FA 1PD8A 3KJRA 1TDRA 3SH2A 3SRUX 1DR3A 1LUDA 1U70A 3GHWA 3FRBX 4NX7A 2L28A 1IA3A 1RX7A 5U26A 4KL9A 3EIGA 1AOEA 3GHCA 3EX8A 4Q67A 3NXVA 1J3KA 1IA1A 3S7AA 4QLGA 3SAIA 4P3RA 1DRBA 3TQ9A 3JWMA 4M6KA 3OAFA 5U27A 3CSEA 1M78A 1RA8A 3GHVA 4XE6X 2C2SA 4H98A 3NXYA 1RX3A 3FY8X 3NXRA 2INQA 1DRHA 3QLRA 2CD2A 3JWFA 1KMSA 2W9HA 5DXVA 4TU5X 4KNEA 4EILA 4KM0A 3DGAA 1IA4A 3I8AX 1KMVA 2ZZAA 3QYLA 4DDRA 3SRRX 4HOEA 3NRRA 3RO9A 1DG7A 2B3ZA 3EELA 4Q6AA 3ZPCA 3FRFX 5HF0X 4ELGA 1S3VA 2W9TA 1DYHA 3QYOA 3FL8A 3NZAX 4QJZD 4PTHA 4KAKA 3JSUA 1CZ3A 3QLXA 4XT7A 1DYRA 2W9SA 4M7UA 4DPDA 1DG8A 3NXTA 2FZJA 1RC4A 3S3VA 4EIZA 4KEBA 4KY8A 3S9UA 1DAJA 3R33A 3F91A 1DHFA 4H96A 1DG5A 3SA2A 4ELEA 1RA1A 3QLZA 3FQ0A 1RX6A 1DR4A 4DFRA 4PSTA 3HBBA 3NTZA 3UM5A 4G8ZX 4DP3A 3SRQX 5HQZA 2FZIA 3JTWA 4ELFA 5HT4A 1MVSA 3NZ6X 3IRMA 4XRBA 3SGYA 3FQZA 4HOFA 1OHJA 2ANOA 1S3YA 4EJ1A 3NZDA 2D5NA 3E0BA 3QG2A 3EEMA 4X5IA 3NZ9X 3SQYX 3QFXA 5HSRA 4XT8A 2ANQA 1S3WA 3F0SX 3FQFA 1DRFA 4XT4A 4M6JA 3CL9A 3DRCA 3KJSA 3F0XX 4HA9A 3GI2A 3FREX 3DG8A 1VJ3A 1S3UA 4KFJA 1KLKA 1M79A 1RF7A 4Q0DA 3DFRA 3HJ3A 4KD7A 3CLBA 4ELHA 4H95A 4I13A 1RX5A 4OR7A 3KFYA 1SEJA 1DYIA 4KYAA 3FQVA 3JW3A 3DAUA 4QI9A 1D1GA 2ITHA 2DRCA 4M7VA 1DRAA 3EEJA 3RG9A 4P66A 5JA3A 1LY4A 3IA4A 1M7AA 1YHOA 3TD8A 1DISA 2W3AA 1DR7A 3FL9A 1RX2A 4X5HA 5HPBA 1RA3A 3I3RA 3CD2A 3JVXA 1J3IA 6DFRA 3F0QX 1DHJA 2G6VA 4NX6A 2QK8A 5JG0X 1RG7A 4LAGX 4LAHX 3QLYA 4ECKA 1JUVA 3FY9X 1DDSA 3FQOA 3OCHA
chains in the Genus database with same CATH superfamily
2D0KA 1HFRA 3DATA 1RX4A 3FRAX 2C2TA 3GYFA 1VDRA 3NZCX 2OBCA 1MVTA 3VCOA 1DR2A 4QLFA 3JW5A 7DFRA 4PSYA 4XT5A 3NXXA 5CCCA 4IXFX 1BZFA 1DYJA 3KY8A 1HFPA 3FYVX 3SRSX 2BL9A 3F0BX 2W3WA 4PSSA 1DF7A 3TQ8A 5HF2X 2HM9A 4EIGA 2W3MA 3EEKA 4PDJA 1DREA 2LF1A 1LY3A 5HVEA 2BLCA 4CD2A 1RA2A 1BOZA 5HVBA 3FS6A 4DPHA 3KGYA 3IA5A 3IX9A 3K45A 2OIPA 1HFQA 3QLWA 4XT6A 4G3MA 5HQYA 4QLEA 4P3QA 3TQBA 2H2QA 5CC9A 4LAEX 5ECXA 4G95A 4RGCA 1PD9A 2JYBA 2W9GA 4Q0EA 5ECCA 3NZBX 2XW7A 3M09A 1DLRA 3ZPGA 1DIUA 8DFRA 3F8YA 1RX1A 5HI6A 3IROA 1RB3A 1U72A 1RD7A 1AO8A 3D84X 4PTJA 1RB2A 3IRNA 4HOGA 2P4GA 1DR6A 4FGGA 3Q1HA 3SRWX 1E26A 1QZFA 2O7PA 1RE7A 5HSUA 4M2XA 3FYWX 4KY4A 3L3RA 3FRDX 1J3JA 2HXVA 4FHBA 1OHKA 4I1NA 4KJJA 4XECX 4H97A 1RA9A 3JWKA 3LG4A 4LEKX 4KJLA 3DL6A 2HQPA 4KBNA 1ZDRA 3F0VX 2W3BA 3QL3A 1JOMA 4QJCA 3DL5A 4P68A 5HT5A 1DR1A 3NXOA 5HUIA 3QGTA 1DR5A 2AZNA 1RH3A 3M08A 1JOLA 3UM6A 3F8ZA 4KM2A 3TQAA 3K2HA 1DLSA 1IA2A 3INVA 5DFRA 2BLAA 3UM8A 4X5GA 2GD9A 1PDBA 2DHFA 4KJKA 2KGKA 3ROAA 3JWCA 3QLSA 4M6LA 4KLXA 2BLBA 4OSGA 4FGHA 1RX8A 3D80A 3SA1A 4IXGX 3N0HA 5FDAA 1DDRA 3NU0A 2CIGA 4HA7A 1U71A 3K74A 4IXED 3SR5X 5EAJA 1DHIA 4QHVA 1CD2A 1AI9A 2FZHA 1RX9A 3F0UX 3QL0A 2W3VA 3FQCA 5E8QA 4X5JA 4ELBA 4GH8A 3K47A 4X5FA 1PD8A 3KJRA 1TDRA 3SH2A 3SRUX 1DR3A 1LUDA 1U70A 3GHWA 3FRBX 4NX7A 2L28A 1IA3A 1RX7A 5U26A 4KL9A 3EIGA 1AOEA 3GHCA 3EX8A 4Q67A 3NXVA 1J3KA 1IA1A 3S7AA 4QLGA 3SAIA 4P3RA 1DRBA 3TQ9A 3JWMA 4M6KA 3OAFA 5U27A 3CSEA 1M78A 1RA8A 3GHVA 4XE6X 2C2SA 4H98A 3NXYA 1RX3A 3FY8X 3NXRA 2INQA 1DRHA 3QLRA 2CD2A 3JWFA 1KMSA 2W9HA 5DXVA 4TU5X 4KNEA 4EILA 4KM0A 3DGAA 1IA4A 3I8AX 1KMVA 2ZZAA 3QYLA 4DDRA 3SRRX 4HOEA 3NRRA 3RO9A 1DG7A 2B3ZA 3EELA 4Q6AA 3ZPCA 3FRFX 5HF0X 4ELGA 1S3VA 2W9TA 1DYHA 3QYOA 3FL8A 3NZAX 4QJZD 4PTHA 4KAKA 3JSUA 1CZ3A 3QLXA 4XT7A 1DYRA 2W9SA 4M7UA 4DPDA 1DG8A 3NXTA 2FZJA 1RC4A 3S3VA 4EIZA 4KEBA 4KY8A 3S9UA 1DAJA 3R33A 3F91A 1DHFA 4H96A 1DG5A 3SA2A 4ELEA 1RA1A 3QLZA 3FQ0A 1RX6A 1DR4A 4DFRA 4PSTA 3HBBA 3NTZA 3UM5A 4G8ZX 4DP3A 3SRQX 5HQZA 2FZIA 3JTWA 4ELFA 5HT4A 1MVSA 3NZ6X 3IRMA 4XRBA 3SGYA 3FQZA 4HOFA 1OHJA 2ANOA 1S3YA 4EJ1A 3NZDA 2D5NA 3E0BA 3QG2A 3EEMA 4X5IA 3NZ9X 3SQYX 3QFXA 5HSRA 4XT8A 2ANQA 1S3WA 3F0SX 3FQFA 1DRFA 4XT4A 4M6JA 3CL9A 3DRCA 3KJSA 3F0XX 4HA9A 3GI2A 3FREX 3DG8A 1VJ3A 1S3UA 4KFJA 1KLKA 1M79A 1RF7A 4Q0DA 3DFRA 3HJ3A 4KD7A 3CLBA 4ELHA 4H95A 4I13A 1RX5A 4OR7A 3KFYA 1SEJA 1DYIA 4KYAA 3FQVA 3JW3A 3DAUA 4QI9A 1D1GA 2ITHA 2DRCA 4M7VA 1DRAA 3EEJA 3RG9A 4P66A 5JA3A 1LY4A 3IA4A 1M7AA 1YHOA 3TD8A 1DISA 2W3AA 1DR7A 3FL9A 1RX2A 4X5HA 5HPBA 1RA3A 3I3RA 3CD2A 3JVXA 1J3IA 6DFRA 3F0QX 1DHJA 2G6VA 4NX6A 2QK8A 5JG0X 1RG7A 4LAGX 4LAHX 3QLYA 4ECKA 1JUVA 3FY9X 1DDSA 3FQOA 3OCHA
chains in the Genus database with same CATH topology
2D0KA 1HFRA 3DATA 1RX4A 3FRAX 2C2TA 3GYFA 1VDRA 3NZCX 2OBCA 1MVTA 3VCOA 1DR2A 4QLFA 3JW5A 7DFRA 4PSYA 4XT5A 3NXXA 5CCCA 4IXFX 1BZFA 1DYJA 3KY8A 1HFPA 3FYVX 3SRSX 2BL9A 3F0BX 2W3WA 4PSSA 1DF7A 3TQ8A 5HF2X 2HM9A 4EIGA 2W3MA 3EEKA 4PDJA 1DREA 2LF1A 1LY3A 5HVEA 2BLCA 4CD2A 1RA2A 1BOZA 5HVBA 3FS6A 4DPHA 3KGYA 3IA5A 3IX9A 3K45A 2OIPA 1HFQA 3QLWA 4XT6A 4G3MA 5HQYA 4QLEA 4P3QA 3TQBA 2H2QA 5CC9A 4LAEX 5ECXA 4G95A 4RGCA 1PD9A 2JYBA 2W9GA 4Q0EA 5ECCA 3NZBX 2XW7A 3M09A 1DLRA 3ZPGA 1DIUA 8DFRA 3F8YA 1RX1A 5HI6A 3IROA 1RB3A 1U72A 1RD7A 1AO8A 3D84X 4PTJA 1RB2A 3IRNA 4HOGA 2P4GA 1DR6A 4FGGA 3Q1HA 3SRWX 1E26A 1QZFA 2O7PA 1RE7A 5HSUA 4M2XA 3FYWX 4KY4A 3L3RA 3FRDX 1J3JA 2HXVA 4FHBA 1OHKA 4I1NA 4KJJA 4XECX 4H97A 1RA9A 3JWKA 3LG4A 4LEKX 4KJLA 3DL6A 2HQPA 4KBNA 1ZDRA 3F0VX 2W3BA 3QL3A 1JOMA 4QJCA 3DL5A 4P68A 5HT5A 1DR1A 3NXOA 5HUIA 3QGTA 1DR5A 2AZNA 1RH3A 3M08A 1JOLA 3UM6A 3F8ZA 4KM2A 3TQAA 3K2HA 1DLSA 1IA2A 3INVA 5DFRA 2BLAA 3UM8A 4X5GA 2GD9A 1PDBA 2DHFA 4KJKA 2KGKA 3ROAA 3JWCA 3QLSA 4M6LA 4KLXA 2BLBA 4OSGA 4FGHA 1RX8A 3D80A 3SA1A 4IXGX 3N0HA 5FDAA 1DDRA 3NU0A 2CIGA 4HA7A 1U71A 3K74A 4IXED 3SR5X 5EAJA 1DHIA 4QHVA 1CD2A 1AI9A 2FZHA 1RX9A 3F0UX 3QL0A 2W3VA 3FQCA 5E8QA 4X5JA 4ELBA 4GH8A 3K47A 4X5FA 1PD8A 3KJRA 1TDRA 3SH2A 3SRUX 1DR3A 1LUDA 1U70A 3GHWA 3FRBX 4NX7A 2L28A 1IA3A 1RX7A 5U26A 4KL9A 3EIGA 1AOEA 3GHCA 3EX8A 4Q67A 3NXVA 1J3KA 1IA1A 3S7AA 4QLGA 3SAIA 4P3RA 1DRBA 3TQ9A 3JWMA 4M6KA 3OAFA 5U27A 3CSEA 1M78A 1RA8A 3GHVA 4XE6X 2C2SA 4H98A 3NXYA 1RX3A 3FY8X 3NXRA 2INQA 1DRHA 3QLRA 2CD2A 3JWFA 1KMSA 2W9HA 5DXVA 4TU5X 4KNEA 4EILA 4KM0A 3DGAA 1IA4A 3I8AX 1KMVA 2ZZAA 3QYLA 4DDRA 3SRRX 4HOEA 3NRRA 3RO9A 1DG7A 2B3ZA 3EELA 4Q6AA 3ZPCA 3FRFX 5HF0X 4ELGA 1S3VA 2W9TA 1DYHA 3QYOA 3FL8A 3NZAX 4QJZD 4PTHA 4KAKA 3JSUA 1CZ3A 3QLXA 4XT7A 1DYRA 2W9SA 4M7UA 4DPDA 1DG8A 3NXTA 2FZJA 1RC4A 3S3VA 4EIZA 4KEBA 4KY8A 3S9UA 1DAJA 3R33A 3F91A 1DHFA 4H96A 1DG5A 3SA2A 4ELEA 1RA1A 3QLZA 3FQ0A 1RX6A 1DR4A 4DFRA 4PSTA 3HBBA 3NTZA 3UM5A 4G8ZX 4DP3A 3SRQX 5HQZA 2FZIA 3JTWA 4ELFA 5HT4A 1MVSA 3NZ6X 3IRMA 4XRBA 3SGYA 3FQZA 4HOFA 1OHJA 2ANOA 1S3YA 4EJ1A 3NZDA 2D5NA 3E0BA 3QG2A 3EEMA 4X5IA 3NZ9X 3SQYX 3QFXA 5HSRA 4XT8A 2ANQA 1S3WA 3F0SX 3FQFA 1DRFA 4XT4A 4M6JA 3CL9A 3DRCA 3KJSA 3F0XX 4HA9A 3GI2A 3FREX 3DG8A 1VJ3A 1S3UA 4KFJA 1KLKA 1M79A 1RF7A 4Q0DA 3DFRA 3HJ3A 4KD7A 3CLBA 4ELHA 4H95A 4I13A 1RX5A 4OR7A 3KFYA 1SEJA 1DYIA 4KYAA 3FQVA 3JW3A 3DAUA 4QI9A 1D1GA 2ITHA 2DRCA 4M7VA 1DRAA 3EEJA 3RG9A 4P66A 5JA3A 1LY4A 3IA4A 1M7AA 1YHOA 3TD8A 1DISA 2W3AA 1DR7A 3FL9A 1RX2A 4X5HA 5HPBA 1RA3A 3I3RA 3CD2A 3JVXA 1J3IA 6DFRA 3F0QX 1DHJA 2G6VA 4NX6A 2QK8A 5JG0X 1RG7A 4LAGX 4LAHX 3QLYA 4ECKA 1JUVA 3FY9X 1DDSA 3FQOA 3OCHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D0K A;  1HFR A;  3DAT A;  1RX4 A;  3FRA X;  2C2T A;  3GYF A;  1VDR A;  3NZC X;  2OBC A;  1MVT A;  3VCO A;  1DR2 A;  4QLF A;  3JW5 A;  7DFR A;  4PSY A;  4XT5 A;  3NXX A;  5CCC A;  4IXF X;  1BZF A;  1DYJ A;  3KY8 A;  1HFP A;  3FYV X;  3SRS X;  2BL9 A;  3F0B X;  2W3W A;  4PSS A;  1DF7 A;  3TQ8 A;  5HF2 X;  2HM9 A;  4EIG A;  2W3M A;  3EEK A;  4PDJ A;  1DRE A;  2LF1 A;  1LY3 A;  5HVE A;  2BLC A;  4CD2 A;  1RA2 A;  1BOZ A;  5HVB A;  3FS6 A;  4DPH A;  3KGY A;  3IA5 A;  3IX9 A;  3K45 A;  2OIP A;  1HFQ A;  3QLW A;  4XT6 A;  4G3M A;  5HQY A;  4QLE A;  4P3Q A;  3TQB A;  2H2Q A;  5CC9 A;  4LAE X;  5ECX A;  4G95 A;  4RGC A;  1PD9 A;  2JYB A;  2W9G A;  4Q0E A;  5ECC A;  3NZB X;  2XW7 A;  3M09 A;  1DLR A;  3ZPG A;  1DIU A;  8DFR A;  3F8Y A;  1RX1 A;  5HI6 A;  3IRO A;  1RB3 A;  1U72 A;  1RD7 A;  1AO8 A;  3D84 X;  4PTJ A;  1RB2 A;  3IRN A;  4HOG A;  2P4G A;  1DR6 A;  4FGG A;  3Q1H A;  3SRW X;  1E26 A;  1QZF A;  2O7P A;  1RE7 A;  5HSU A;  4M2X A;  3FYW X;  4KY4 A;  3L3R A;  3FRD X;  1J3J A;  2HXV A;  4FHB A;  1OHK A;  4I1N A;  4KJJ A;  4XEC X;  4H97 A;  1RA9 A;  3JWK A;  3LG4 A;  4LEK X;  4KJL A;  3DL6 A;  2HQP A;  4KBN A;  1ZDR A;  3F0V X;  2W3B A;  3QL3 A;  1JOM A;  4QJC A;  3DL5 A;  4P68 A;  5HT5 A;  1DR1 A;  3NXO A;  5HUI A;  3QGT A;  1DR5 A;  2AZN A;  1RH3 A;  3M08 A;  1JOL A;  3UM6 A;  3F8Z A;  4KM2 A;  3TQA A;  3K2H A;  1DLS A;  1IA2 A;  3INV A;  5DFR A;  2BLA A;  3UM8 A;  4X5G A;  2GD9 A;  1PDB A;  2DHF A;  4KJK A;  2KGK A;  3ROA A;  3JWC A;  3QLS A;  4M6L A;  4KLX A;  2BLB A;  4OSG A;  4FGH A;  1RX8 A;  3D80 A;  3SA1 A;  4IXG X;  3N0H A;  5FDA A;  1DDR A;  3NU0 A;  2CIG A;  4HA7 A;  1U71 A;  3K74 A;  4IXE D;  3SR5 X;  5EAJ A;  1DHI A;  4QHV A;  1CD2 A;  1AI9 A;  2FZH A;  1RX9 A;  3F0U X;  3QL0 A;  2W3V A;  3FQC A;  5E8Q A;  4X5J A;  4ELB A;  4GH8 A;  3K47 A;  4X5F A;  1PD8 A;  3KJR A;  1TDR A;  3SH2 A;  3SRU X;  1DR3 A;  1LUD A;  1U70 A;  3GHW A;  3FRB X;  4NX7 A;  2L28 A;  1IA3 A;  1RX7 A;  5U26 A;  4KL9 A;  3EIG A;  1AOE A;  3GHC A;  3EX8 A;  4Q67 A;  3NXV A;  1J3K A;  1IA1 A;  3S7A A;  4QLG A;  3SAI A;  4P3R A;  1DRB A;  3TQ9 A;  3JWM A;  4M6K A;  3OAF A;  5U27 A;  3CSE A;  1M78 A;  1RA8 A;  3GHV A;  4XE6 X;  2C2S A;  4H98 A;  3NXY A;  1RX3 A;  3FY8 X;  3NXR A;  2INQ A;  1DRH A;  3QLR A;  2CD2 A;  3JWF A;  1KMS A;  2W9H A;  5DXV A;  4TU5 X;  4KNE A;  4EIL A;  4KM0 A;  3DGA A;  1IA4 A;  3I8A X;  1KMV A;  2ZZA A;  3QYL A;  4DDR A;  3SRR X;  4HOE A;  3NRR A;  3RO9 A;  1DG7 A;  2B3Z A;  3EEL A;  4Q6A A;  3ZPC A;  3FRF X;  5HF0 X;  4ELG A;  1S3V A;  2W9T A;  1DYH A;  3QYO A;  3FL8 A;  3NZA X;  4QJZ D;  4PTH A;  4KAK A;  3JSU A;  1CZ3 A;  3QLX A;  4XT7 A;  1DYR A;  2W9S A;  4M7U A;  4DPD A;  1DG8 A;  3NXT A;  2FZJ A;  1RC4 A;  3S3V A;  4EIZ A;  4KEB A;  4KY8 A;  3S9U A;  1DAJ A;  3R33 A;  3F91 A;  1DHF A;  4H96 A;  1DG5 A;  3SA2 A;  4ELE A;  1RA1 A;  3QLZ A;  3FQ0 A;  1RX6 A;  1DR4 A;  4DFR A;  4PST A;  3HBB A;  3NTZ A;  3UM5 A;  4G8Z X;  4DP3 A;  3SRQ X;  5HQZ A;  2FZI A;  3JTW A;  4ELF A;  5HT4 A;  1MVS A;  3NZ6 X;  3IRM A;  4XRB A;  3SGY A;  3FQZ A;  4HOF A;  1OHJ A;  2ANO A;  1S3Y A;  4EJ1 A;  3NZD A;  2D5N A;  3E0B A;  3QG2 A;  3EEM A;  4X5I A;  3NZ9 X;  3SQY X;  3QFX A;  5HSR A;  4XT8 A;  2ANQ A;  1S3W A;  3F0S X;  3FQF A;  1DRF A;  4XT4 A;  4M6J A;  3CL9 A;  3DRC A;  3KJS A;  3F0X X;  4HA9 A;  3GI2 A;  3FRE X;  3DG8 A;  1VJ3 A;  1S3U A;  4KFJ A;  1KLK A;  1M79 A;  1RF7 A;  4Q0D A;  3DFR A;  3HJ3 A;  4KD7 A;  3CLB A;  4ELH A;  4H95 A;  4I13 A;  1RX5 A;  4OR7 A;  3KFY A;  1SEJ A;  1DYI A;  4KYA A;  3FQV A;  3JW3 A;  3DAU A;  4QI9 A;  1D1G A;  2ITH A;  2DRC A;  4M7V A;  1DRA A;  3EEJ A;  3RG9 A;  4P66 A;  5JA3 A;  1LY4 A;  3IA4 A;  1M7A A;  1YHO A;  3TD8 A;  1DIS A;  2W3A A;  1DR7 A;  3FL9 A;  1RX2 A;  4X5H A;  5HPB A;  1RA3 A;  3I3R A;  3CD2 A;  3JVX A;  1J3I A;  6DFR A;  3F0Q X;  1DHJ A;  2G6V A;  4NX6 A;  2QK8 A;  5JG0 X;  1RG7 A;  4LAG X;  4LAH X;  3QLY A;  4ECK A;  1JUV A;  3FY9 X;  1DDS A;  3FQO A;  3OCH A; 
#chains in the Genus database with same CATH topology
 2D0K A;  1HFR A;  3DAT A;  1RX4 A;  3FRA X;  2C2T A;  3GYF A;  1VDR A;  3NZC X;  2OBC A;  1MVT A;  3VCO A;  1DR2 A;  4QLF A;  3JW5 A;  7DFR A;  4PSY A;  4XT5 A;  3NXX A;  5CCC A;  4IXF X;  1BZF A;  1DYJ A;  3KY8 A;  1HFP A;  3FYV X;  3SRS X;  2BL9 A;  3F0B X;  2W3W A;  4PSS A;  1DF7 A;  3TQ8 A;  5HF2 X;  2HM9 A;  4EIG A;  2W3M A;  3EEK A;  4PDJ A;  1DRE A;  2LF1 A;  1LY3 A;  5HVE A;  2BLC A;  4CD2 A;  1RA2 A;  1BOZ A;  5HVB A;  3FS6 A;  4DPH A;  3KGY A;  3IA5 A;  3IX9 A;  3K45 A;  2OIP A;  1HFQ A;  3QLW A;  4XT6 A;  4G3M A;  5HQY A;  4QLE A;  4P3Q A;  3TQB A;  2H2Q A;  5CC9 A;  4LAE X;  5ECX A;  4G95 A;  4RGC A;  1PD9 A;  2JYB A;  2W9G A;  4Q0E A;  5ECC A;  3NZB X;  2XW7 A;  3M09 A;  1DLR A;  3ZPG A;  1DIU A;  8DFR A;  3F8Y A;  1RX1 A;  5HI6 A;  3IRO A;  1RB3 A;  1U72 A;  1RD7 A;  1AO8 A;  3D84 X;  4PTJ A;  1RB2 A;  3IRN A;  4HOG A;  2P4G A;  1DR6 A;  4FGG A;  3Q1H A;  3SRW X;  1E26 A;  1QZF A;  2O7P A;  1RE7 A;  5HSU A;  4M2X A;  3FYW X;  4KY4 A;  3L3R A;  3FRD X;  1J3J A;  2HXV A;  4FHB A;  1OHK A;  4I1N A;  4KJJ A;  4XEC X;  4H97 A;  1RA9 A;  3JWK A;  3LG4 A;  4LEK X;  4KJL A;  3DL6 A;  2HQP A;  4KBN A;  1ZDR A;  3F0V X;  2W3B A;  3QL3 A;  1JOM A;  4QJC A;  3DL5 A;  4P68 A;  5HT5 A;  1DR1 A;  3NXO A;  5HUI A;  3QGT A;  1DR5 A;  2AZN A;  1RH3 A;  3M08 A;  1JOL A;  3UM6 A;  3F8Z A;  4KM2 A;  3TQA A;  3K2H A;  1DLS A;  1IA2 A;  3INV A;  5DFR A;  2BLA A;  3UM8 A;  4X5G A;  2GD9 A;  1PDB A;  2DHF A;  4KJK A;  2KGK A;  3ROA A;  3JWC A;  3QLS A;  4M6L A;  4KLX A;  2BLB A;  4OSG A;  4FGH A;  1RX8 A;  3D80 A;  3SA1 A;  4IXG X;  3N0H A;  5FDA A;  1DDR A;  3NU0 A;  2CIG A;  4HA7 A;  1U71 A;  3K74 A;  4IXE D;  3SR5 X;  5EAJ A;  1DHI A;  4QHV A;  1CD2 A;  1AI9 A;  2FZH A;  1RX9 A;  3F0U X;  3QL0 A;  2W3V A;  3FQC A;  5E8Q A;  4X5J A;  4ELB A;  4GH8 A;  3K47 A;  4X5F A;  1PD8 A;  3KJR A;  1TDR A;  3SH2 A;  3SRU X;  1DR3 A;  1LUD A;  1U70 A;  3GHW A;  3FRB X;  4NX7 A;  2L28 A;  1IA3 A;  1RX7 A;  5U26 A;  4KL9 A;  3EIG A;  1AOE A;  3GHC A;  3EX8 A;  4Q67 A;  3NXV A;  1J3K A;  1IA1 A;  3S7A A;  4QLG A;  3SAI A;  4P3R A;  1DRB A;  3TQ9 A;  3JWM A;  4M6K A;  3OAF A;  5U27 A;  3CSE A;  1M78 A;  1RA8 A;  3GHV A;  4XE6 X;  2C2S A;  4H98 A;  3NXY A;  1RX3 A;  3FY8 X;  3NXR A;  2INQ A;  1DRH A;  3QLR A;  2CD2 A;  3JWF A;  1KMS A;  2W9H A;  5DXV A;  4TU5 X;  4KNE A;  4EIL A;  4KM0 A;  3DGA A;  1IA4 A;  3I8A X;  1KMV A;  2ZZA A;  3QYL A;  4DDR A;  3SRR X;  4HOE A;  3NRR A;  3RO9 A;  1DG7 A;  2B3Z A;  3EEL A;  4Q6A A;  3ZPC A;  3FRF X;  5HF0 X;  4ELG A;  1S3V A;  2W9T A;  1DYH A;  3QYO A;  3FL8 A;  3NZA X;  4QJZ D;  4PTH A;  4KAK A;  3JSU A;  1CZ3 A;  3QLX A;  4XT7 A;  1DYR A;  2W9S A;  4M7U A;  4DPD A;  1DG8 A;  3NXT A;  2FZJ A;  1RC4 A;  3S3V A;  4EIZ A;  4KEB A;  4KY8 A;  3S9U A;  1DAJ A;  3R33 A;  3F91 A;  1DHF A;  4H96 A;  1DG5 A;  3SA2 A;  4ELE A;  1RA1 A;  3QLZ A;  3FQ0 A;  1RX6 A;  1DR4 A;  4DFR A;  4PST A;  3HBB A;  3NTZ A;  3UM5 A;  4G8Z X;  4DP3 A;  3SRQ X;  5HQZ A;  2FZI A;  3JTW A;  4ELF A;  5HT4 A;  1MVS A;  3NZ6 X;  3IRM A;  4XRB A;  3SGY A;  3FQZ A;  4HOF A;  1OHJ A;  2ANO A;  1S3Y A;  4EJ1 A;  3NZD A;  2D5N A;  3E0B A;  3QG2 A;  3EEM A;  4X5I A;  3NZ9 X;  3SQY X;  3QFX A;  5HSR A;  4XT8 A;  2ANQ A;  1S3W A;  3F0S X;  3FQF A;  1DRF A;  4XT4 A;  4M6J A;  3CL9 A;  3DRC A;  3KJS A;  3F0X X;  4HA9 A;  3GI2 A;  3FRE X;  3DG8 A;  1VJ3 A;  1S3U A;  4KFJ A;  1KLK A;  1M79 A;  1RF7 A;  4Q0D A;  3DFR A;  3HJ3 A;  4KD7 A;  3CLB A;  4ELH A;  4H95 A;  4I13 A;  1RX5 A;  4OR7 A;  3KFY A;  1SEJ A;  1DYI A;  4KYA A;  3FQV A;  3JW3 A;  3DAU A;  4QI9 A;  1D1G A;  2ITH A;  2DRC A;  4M7V A;  1DRA A;  3EEJ A;  3RG9 A;  4P66 A;  5JA3 A;  1LY4 A;  3IA4 A;  1M7A A;  1YHO A;  3TD8 A;  1DIS A;  2W3A A;  1DR7 A;  3FL9 A;  1RX2 A;  4X5H A;  5HPB A;  1RA3 A;  3I3R A;  3CD2 A;  3JVX A;  1J3I A;  6DFR A;  3F0Q X;  1DHJ A;  2G6V A;  4NX6 A;  2QK8 A;  5JG0 X;  1RG7 A;  4LAG X;  4LAH X;  3QLY A;  4ECK A;  1JUV A;  3FY9 X;  1DDS A;  3FQO A;  3OCH A; 
#chains in the Genus database with same CATH homology
 2D0K A;  1HFR A;  3DAT A;  1RX4 A;  3FRA X;  2C2T A;  3GYF A;  1VDR A;  3NZC X;  2OBC A;  1MVT A;  3VCO A;  1DR2 A;  4QLF A;  3JW5 A;  7DFR A;  4PSY A;  4XT5 A;  3NXX A;  5CCC A;  4IXF X;  1BZF A;  1DYJ A;  3KY8 A;  1HFP A;  3FYV X;  3SRS X;  2BL9 A;  3F0B X;  2W3W A;  4PSS A;  1DF7 A;  3TQ8 A;  5HF2 X;  2HM9 A;  4EIG A;  2W3M A;  3EEK A;  4PDJ A;  1DRE A;  2LF1 A;  1LY3 A;  5HVE A;  2BLC A;  4CD2 A;  1RA2 A;  1BOZ A;  5HVB A;  3FS6 A;  4DPH A;  3KGY A;  3IA5 A;  3IX9 A;  3K45 A;  2OIP A;  1HFQ A;  3QLW A;  4XT6 A;  4G3M A;  5HQY A;  4QLE A;  4P3Q A;  3TQB A;  2H2Q A;  5CC9 A;  4LAE X;  5ECX A;  4G95 A;  4RGC A;  1PD9 A;  2JYB A;  2W9G A;  4Q0E A;  5ECC A;  3NZB X;  2XW7 A;  3M09 A;  1DLR A;  3ZPG A;  1DIU A;  8DFR A;  3F8Y A;  1RX1 A;  5HI6 A;  3IRO A;  1RB3 A;  1U72 A;  1RD7 A;  1AO8 A;  3D84 X;  4PTJ A;  1RB2 A;  3IRN A;  4HOG A;  2P4G A;  1DR6 A;  4FGG A;  3Q1H A;  3SRW X;  1E26 A;  1QZF A;  2O7P A;  1RE7 A;  5HSU A;  4M2X A;  3FYW X;  4KY4 A;  3L3R A;  3FRD X;  1J3J A;  2HXV A;  4FHB A;  1OHK A;  4I1N A;  4KJJ A;  4XEC X;  4H97 A;  1RA9 A;  3JWK A;  3LG4 A;  4LEK X;  4KJL A;  3DL6 A;  2HQP A;  4KBN A;  1ZDR A;  3F0V X;  2W3B A;  3QL3 A;  1JOM A;  4QJC A;  3DL5 A;  4P68 A;  5HT5 A;  1DR1 A;  3NXO A;  5HUI A;  3QGT A;  1DR5 A;  2AZN A;  1RH3 A;  3M08 A;  1JOL A;  3UM6 A;  3F8Z A;  4KM2 A;  3TQA A;  3K2H A;  1DLS A;  1IA2 A;  3INV A;  5DFR A;  2BLA A;  3UM8 A;  4X5G A;  2GD9 A;  1PDB A;  2DHF A;  4KJK A;  2KGK A;  3ROA A;  3JWC A;  3QLS A;  4M6L A;  4KLX A;  2BLB A;  4OSG A;  4FGH A;  1RX8 A;  3D80 A;  3SA1 A;  4IXG X;  3N0H A;  5FDA A;  1DDR A;  3NU0 A;  2CIG A;  4HA7 A;  1U71 A;  3K74 A;  4IXE D;  3SR5 X;  5EAJ A;  1DHI A;  4QHV A;  1CD2 A;  1AI9 A;  2FZH A;  1RX9 A;  3F0U X;  3QL0 A;  2W3V A;  3FQC A;  5E8Q A;  4X5J A;  4ELB A;  4GH8 A;  3K47 A;  4X5F A;  1PD8 A;  3KJR A;  1TDR A;  3SH2 A;  3SRU X;  1DR3 A;  1LUD A;  1U70 A;  3GHW A;  3FRB X;  4NX7 A;  2L28 A;  1IA3 A;  1RX7 A;  5U26 A;  4KL9 A;  3EIG A;  1AOE A;  3GHC A;  3EX8 A;  4Q67 A;  3NXV A;  1J3K A;  1IA1 A;  3S7A A;  4QLG A;  3SAI A;  4P3R A;  1DRB A;  3TQ9 A;  3JWM A;  4M6K A;  3OAF A;  5U27 A;  3CSE A;  1M78 A;  1RA8 A;  3GHV A;  4XE6 X;  2C2S A;  4H98 A;  3NXY A;  1RX3 A;  3FY8 X;  3NXR A;  2INQ A;  1DRH A;  3QLR A;  2CD2 A;  3JWF A;  1KMS A;  2W9H A;  5DXV A;  4TU5 X;  4KNE A;  4EIL A;  4KM0 A;  3DGA A;  1IA4 A;  3I8A X;  1KMV A;  2ZZA A;  3QYL A;  4DDR A;  3SRR X;  4HOE A;  3NRR A;  3RO9 A;  1DG7 A;  2B3Z A;  3EEL A;  4Q6A A;  3ZPC A;  3FRF X;  5HF0 X;  4ELG A;  1S3V A;  2W9T A;  1DYH A;  3QYO A;  3FL8 A;  3NZA X;  4QJZ D;  4PTH A;  4KAK A;  3JSU A;  1CZ3 A;  3QLX A;  4XT7 A;  1DYR A;  2W9S A;  4M7U A;  4DPD A;  1DG8 A;  3NXT A;  2FZJ A;  1RC4 A;  3S3V A;  4EIZ A;  4KEB A;  4KY8 A;  3S9U A;  1DAJ A;  3R33 A;  3F91 A;  1DHF A;  4H96 A;  1DG5 A;  3SA2 A;  4ELE A;  1RA1 A;  3QLZ A;  3FQ0 A;  1RX6 A;  1DR4 A;  4DFR A;  4PST A;  3HBB A;  3NTZ A;  3UM5 A;  4G8Z X;  4DP3 A;  3SRQ X;  5HQZ A;  2FZI A;  3JTW A;  4ELF A;  5HT4 A;  1MVS A;  3NZ6 X;  3IRM A;  4XRB A;  3SGY A;  3FQZ A;  4HOF A;  1OHJ A;  2ANO A;  1S3Y A;  4EJ1 A;  3NZD A;  2D5N A;  3E0B A;  3QG2 A;  3EEM A;  4X5I A;  3NZ9 X;  3SQY X;  3QFX A;  5HSR A;  4XT8 A;  2ANQ A;  1S3W A;  3F0S X;  3FQF A;  1DRF A;  4XT4 A;  4M6J A;  3CL9 A;  3DRC A;  3KJS A;  3F0X X;  4HA9 A;  3GI2 A;  3FRE X;  3DG8 A;  1VJ3 A;  1S3U A;  4KFJ A;  1KLK A;  1M79 A;  1RF7 A;  4Q0D A;  3DFR A;  3HJ3 A;  4KD7 A;  3CLB A;  4ELH A;  4H95 A;  4I13 A;  1RX5 A;  4OR7 A;  3KFY A;  1SEJ A;  1DYI A;  4KYA A;  3FQV A;  3JW3 A;  3DAU A;  4QI9 A;  1D1G A;  2ITH A;  2DRC A;  4M7V A;  1DRA A;  3EEJ A;  3RG9 A;  4P66 A;  5JA3 A;  1LY4 A;  3IA4 A;  1M7A A;  1YHO A;  3TD8 A;  1DIS A;  2W3A A;  1DR7 A;  3FL9 A;  1RX2 A;  4X5H A;  5HPB A;  1RA3 A;  3I3R A;  3CD2 A;  3JVX A;  1J3I A;  6DFR A;  3F0Q X;  1DHJ A;  2G6V A;  4NX6 A;  2QK8 A;  5JG0 X;  1RG7 A;  4LAG X;  4LAH X;  3QLY A;  4ECK A;  1JUV A;  3FY9 X;  1DDS A;  3FQO A;  3OCH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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