4PTHA

Ensemble model for escherichia coli dihydrofolate reductase at 100k
Total Genus 44
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
158
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Dihydrofolate reductase
total genus 44
structure length 158
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-03-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4pthA00
4H97A 3DG8A 3TQBA 3CSEA 3DATA 4HOEA 5HUIA 2CIGA 3F0VX 3GI2A 3SH2A 3NXTA 1OHKA 5EAJA 2W9TA 5ECXA 3KJSA 4X5FA 1LUDA 3EEKA 4PSYA 4GH8A 3N0HA 3KJRA 4X5HA 3HBBA 4EIGA 3S3VA 4ELGA 1RC4A 1BZFA 3QL0A 3INVA 3TQAA 1DG5A 3QLRA 2C2TA 7DFRA 3UM8A 3NZDA 5HVBA 3JW3A 2AZNA 3FY9X 4QJCA 4XT4A 4P3RA 3DL5A 2W9GA 4XT6A 4QLFA 4QLEA 3NZAX 4IXGX 4X5IA 3DAUA 2FZHA 4XT8A 1DRBA 4FGGA 3JW5A 1DHJA 1RX7A 4DDRA 4PSSA 8DFRA 3IRMA 3LG4A 4ELFA 5HT4A 2ZZAA 2ANOA 3IRNA 2L28A 1DR3A 1IA2A 4DP3A 3IA4A 3SA2A 3QLZA 1DYRA 3GHWA 1J3JA 1DR5A 1AI9A 4KYAA 3F0XX 2C2SA 2GD9A 3JWMA 4Q0EA 3FRBX 3ZPGA 3TQ9A 4DFRA 4PTHA 3Q1HA 4XE6X 1DRAA 3NXRA 2BL9A 4LEKX 2QK8A 1J3KA 3QLYA 3EX8A 4NX7A 2D0KA 5DFRA 3IX9A 5U27A 3IROA 3KY8A 2LF1A 1RX2A 4Q6AA 3F8ZA 2BLCA 4FHBA 4QJZD 3NXXA 3SRUX 1AOEA 1U70A 3ZPCA 1D1GA 1PD9A 4XT7A 4KFJA 1IA1A 3NZ6X 2W3WA 1RX6A 3EELA 1MVTA 1RX1A 1RA9A 1OHJA 3UM6A 1DR2A 4KLXA 4RGCA 3KFYA 4CD2A 1ZDRA 3SAIA 3FRAX 2ITHA 5HI6A 1S3YA 4Q67A 4M6LA 1VDRA 3S9UA 3EIGA 4XECX 1S3VA 1DF7A 3NZ9X 1JOMA 3JWKA 4P3QA 4G95A 3FQZA 2FZIA 5HPBA 1LY4A 4EJ1A 3OAFA 1IA3A 4HOGA 1RA3A 3GYFA 2B3ZA 3GHCA 3UM5A 1PD8A 2FZJA 5HSRA 2W9SA 4M7VA 4KBNA 2DHFA 2W9HA 2DRCA 3SRRX 4M2XA 3NZCX 5JA3A 4KEBA 5HQYA 3NXYA 3JWFA 3QLWA 2O7PA 1RX4A 3ROAA 3F0UX 1MVSA 3NU0A 1M78A 4KJKA 1E26A 2OIPA 1DAJA 4LAEX 4H95A 3JVXA 1RE7A 3CL9A 3VCOA 1CZ3A 3FQCA 1DR4A 3RG9A 1DRHA 3FYVX 1RX5A 3FREX 3CD2A 5E8QA 2INQA 4OSGA 3FL9A 1SEJA 4KM2A 1JUVA 3M08A 3F0QX 1KLKA 1PDBA 2BLAA 3FQ0A 2G6VA 4QHVA 4XT5A 3QLXA 5FDAA 1U72A 4P66A 4EILA 4HA7A 4IXED 3R33A 5U26A 3QYLA 4ELHA 3SRSX 3TD8A 4EIZA 3D80A 5CCCA 4Q0DA 4ECKA 3NXOA 3F91A 3FQFA 1RB3A 4DPDA 4H96A 1KMSA 1RX9A 4G3MA 3FQOA 1DR1A 1DLSA 5HVEA 3DGAA 1RX8A 3NXVA 1DR7A 1U71A 2HXVA 1RF7A 4M7UA 5HF2X 3F0SX 3K47A 3QL3A 5HF0X 1DYJA 6DFRA 4PDJA 1M7AA 1RD7A 1DG8A 1DYIA 4I13A 4HA9A 1RG7A 4IXFX 4KJLA 2JYBA 4P68A 3EEMA 4TU5X 3DL6A 4PSTA 5JG0X 4DPHA 3D84X 1QZFA 2KGKA 3FRDX 5HSUA 4I1NA 4X5JA 5ECCA 3OCHA 2HQPA 2W3BA 2P4GA 1LY3A 2ANQA 3I8AX 3SGYA 4KL9A 1JOLA 3JTWA 4KY4A 1RA8A 1DDRA 1RA1A 3QGTA 3SA1A 1VJ3A 4ELEA 3M09A 1HFRA 3CLBA 3HJ3A 4KAKA 1HFPA 1AO8A 3K2HA 2H2QA 1DYHA 2OBCA 3FQVA 3FRFX 5CC9A 1DREA 1RH3A 2W3MA 4KD7A 4M6KA 3RO9A 1M79A 4X5GA 5HQZA 1DIUA 3K45A 4XRBA 3K74A 4ELBA 3QG2A 3GHVA 3FYWX 4QLGA 4NX6A 1J3IA 4M6JA 4KJJA 2CD2A 3FL8A 3NZBX 4KNEA 1S3WA 3FS6A 3S7AA 4LAGX 3E0BA 3SQYX 1YHOA 4PTJA 1DDSA 3SRQX 4QI9A 3JWCA 2XW7A 4OR7A 5DXVA 1HFQA 3KGYA 3DRCA 1RA2A 2W3AA 1DG7A 4H98A 1CD2A 3QLSA 4G8ZX 4LAHX 1TDRA 1DR6A 4FGHA 3I3RA 3JSUA 2HM9A 1IA4A 4HOFA 3SRWX 1DLRA 3QFXA 1BOZA 3FY8X 2BLBA 3QYOA 3TQ8A 3F0BX 2D5NA 2W3VA 1DRFA 3NRRA 3F8YA 3NTZA 1RX3A 3EEJA 3DFRA 3L3RA 5HT5A 3SR5X 1KMVA 4KM0A 1RB2A 1S3UA 1DHFA 3IA5A 4KY8A 1DISA 1DHIA
chains in the Genus database with same CATH superfamily
4H97A 3DG8A 3TQBA 3CSEA 3DATA 4HOEA 5HUIA 2CIGA 3F0VX 3GI2A 3SH2A 3NXTA 1OHKA 5EAJA 2W9TA 5ECXA 3KJSA 4X5FA 1LUDA 3EEKA 4PSYA 4GH8A 3N0HA 3KJRA 4X5HA 3HBBA 4EIGA 3S3VA 4ELGA 1RC4A 1BZFA 3QL0A 3INVA 3TQAA 1DG5A 3QLRA 2C2TA 7DFRA 3UM8A 3NZDA 5HVBA 3JW3A 2AZNA 3FY9X 4QJCA 4XT4A 4P3RA 3DL5A 2W9GA 4XT6A 4QLFA 4QLEA 3NZAX 4IXGX 4X5IA 3DAUA 2FZHA 4XT8A 1DRBA 4FGGA 3JW5A 1DHJA 1RX7A 4DDRA 4PSSA 8DFRA 3IRMA 3LG4A 4ELFA 5HT4A 2ZZAA 2ANOA 3IRNA 2L28A 1DR3A 1IA2A 4DP3A 3IA4A 3SA2A 3QLZA 1DYRA 3GHWA 1J3JA 1DR5A 1AI9A 4KYAA 3F0XX 2C2SA 2GD9A 3JWMA 4Q0EA 3FRBX 3ZPGA 3TQ9A 4DFRA 4PTHA 3Q1HA 4XE6X 1DRAA 3NXRA 2BL9A 4LEKX 2QK8A 1J3KA 3QLYA 3EX8A 4NX7A 2D0KA 5DFRA 3IX9A 5U27A 3IROA 3KY8A 2LF1A 1RX2A 4Q6AA 3F8ZA 2BLCA 4FHBA 4QJZD 3NXXA 3SRUX 1AOEA 1U70A 3ZPCA 1D1GA 1PD9A 4XT7A 4KFJA 1IA1A 3NZ6X 2W3WA 1RX6A 3EELA 1MVTA 1RX1A 1RA9A 1OHJA 3UM6A 1DR2A 4KLXA 4RGCA 3KFYA 4CD2A 1ZDRA 3SAIA 3FRAX 2ITHA 5HI6A 1S3YA 4Q67A 4M6LA 1VDRA 3S9UA 3EIGA 4XECX 1S3VA 1DF7A 3NZ9X 1JOMA 3JWKA 4P3QA 4G95A 3FQZA 2FZIA 5HPBA 1LY4A 4EJ1A 3OAFA 1IA3A 4HOGA 1RA3A 3GYFA 2B3ZA 3GHCA 3UM5A 1PD8A 2FZJA 5HSRA 2W9SA 4M7VA 4KBNA 2DHFA 2W9HA 2DRCA 3SRRX 4M2XA 3NZCX 5JA3A 4KEBA 5HQYA 3NXYA 3JWFA 3QLWA 2O7PA 1RX4A 3ROAA 3F0UX 1MVSA 3NU0A 1M78A 4KJKA 1E26A 2OIPA 1DAJA 4LAEX 4H95A 3JVXA 1RE7A 3CL9A 3VCOA 1CZ3A 3FQCA 1DR4A 3RG9A 1DRHA 3FYVX 1RX5A 3FREX 3CD2A 5E8QA 2INQA 4OSGA 3FL9A 1SEJA 4KM2A 1JUVA 3M08A 3F0QX 1KLKA 1PDBA 2BLAA 3FQ0A 2G6VA 4QHVA 4XT5A 3QLXA 5FDAA 1U72A 4P66A 4EILA 4HA7A 4IXED 3R33A 5U26A 3QYLA 4ELHA 3SRSX 3TD8A 4EIZA 3D80A 5CCCA 4Q0DA 4ECKA 3NXOA 3F91A 3FQFA 1RB3A 4DPDA 4H96A 1KMSA 1RX9A 4G3MA 3FQOA 1DR1A 1DLSA 5HVEA 3DGAA 1RX8A 3NXVA 1DR7A 1U71A 2HXVA 1RF7A 4M7UA 5HF2X 3F0SX 3K47A 3QL3A 5HF0X 1DYJA 6DFRA 4PDJA 1M7AA 1RD7A 1DG8A 1DYIA 4I13A 4HA9A 1RG7A 4IXFX 4KJLA 2JYBA 4P68A 3EEMA 4TU5X 3DL6A 4PSTA 5JG0X 4DPHA 3D84X 1QZFA 2KGKA 3FRDX 5HSUA 4I1NA 4X5JA 5ECCA 3OCHA 2HQPA 2W3BA 2P4GA 1LY3A 2ANQA 3I8AX 3SGYA 4KL9A 1JOLA 3JTWA 4KY4A 1RA8A 1DDRA 1RA1A 3QGTA 3SA1A 1VJ3A 4ELEA 3M09A 1HFRA 3CLBA 3HJ3A 4KAKA 1HFPA 1AO8A 3K2HA 2H2QA 1DYHA 2OBCA 3FQVA 3FRFX 5CC9A 1DREA 1RH3A 2W3MA 4KD7A 4M6KA 3RO9A 1M79A 4X5GA 5HQZA 1DIUA 3K45A 4XRBA 3K74A 4ELBA 3QG2A 3GHVA 3FYWX 4QLGA 4NX6A 1J3IA 4M6JA 4KJJA 2CD2A 3FL8A 3NZBX 4KNEA 1S3WA 3FS6A 3S7AA 4LAGX 3E0BA 3SQYX 1YHOA 4PTJA 1DDSA 3SRQX 4QI9A 3JWCA 2XW7A 4OR7A 5DXVA 1HFQA 3KGYA 3DRCA 1RA2A 2W3AA 1DG7A 4H98A 1CD2A 3QLSA 4G8ZX 4LAHX 1TDRA 1DR6A 4FGHA 3I3RA 3JSUA 2HM9A 1IA4A 4HOFA 3SRWX 1DLRA 3QFXA 1BOZA 3FY8X 2BLBA 3QYOA 3TQ8A 3F0BX 2D5NA 2W3VA 1DRFA 3NRRA 3F8YA 3NTZA 1RX3A 3EEJA 3DFRA 3L3RA 5HT5A 3SR5X 1KMVA 4KM0A 1RB2A 1S3UA 1DHFA 3IA5A 4KY8A 1DISA 1DHIA
chains in the Genus database with same CATH topology
4H97A 3DG8A 3TQBA 3CSEA 3DATA 4HOEA 5HUIA 2CIGA 3F0VX 3GI2A 3SH2A 3NXTA 1OHKA 5EAJA 2W9TA 5ECXA 3KJSA 4X5FA 1LUDA 3EEKA 4PSYA 4GH8A 3N0HA 3KJRA 4X5HA 3HBBA 4EIGA 3S3VA 4ELGA 1RC4A 1BZFA 3QL0A 3INVA 3TQAA 1DG5A 3QLRA 2C2TA 7DFRA 3UM8A 3NZDA 5HVBA 3JW3A 2AZNA 3FY9X 4QJCA 4XT4A 4P3RA 3DL5A 2W9GA 4XT6A 4QLFA 4QLEA 3NZAX 4IXGX 4X5IA 3DAUA 2FZHA 4XT8A 1DRBA 4FGGA 3JW5A 1DHJA 1RX7A 4DDRA 4PSSA 8DFRA 3IRMA 3LG4A 4ELFA 5HT4A 2ZZAA 2ANOA 3IRNA 2L28A 1DR3A 1IA2A 4DP3A 3IA4A 3SA2A 3QLZA 1DYRA 3GHWA 1J3JA 1DR5A 1AI9A 4KYAA 3F0XX 2C2SA 2GD9A 3JWMA 4Q0EA 3FRBX 3ZPGA 3TQ9A 4DFRA 4PTHA 3Q1HA 4XE6X 1DRAA 3NXRA 2BL9A 4LEKX 2QK8A 1J3KA 3QLYA 3EX8A 4NX7A 2D0KA 5DFRA 3IX9A 5U27A 3IROA 3KY8A 2LF1A 1RX2A 4Q6AA 3F8ZA 2BLCA 4FHBA 4QJZD 3NXXA 3SRUX 1AOEA 1U70A 3ZPCA 1D1GA 1PD9A 4XT7A 4KFJA 1IA1A 3NZ6X 2W3WA 1RX6A 3EELA 1MVTA 1RX1A 1RA9A 1OHJA 3UM6A 1DR2A 4KLXA 4RGCA 3KFYA 4CD2A 1ZDRA 3SAIA 3FRAX 2ITHA 5HI6A 1S3YA 4Q67A 4M6LA 1VDRA 3S9UA 3EIGA 4XECX 1S3VA 1DF7A 3NZ9X 1JOMA 3JWKA 4P3QA 4G95A 3FQZA 2FZIA 5HPBA 1LY4A 4EJ1A 3OAFA 1IA3A 4HOGA 1RA3A 3GYFA 2B3ZA 3GHCA 3UM5A 1PD8A 2FZJA 5HSRA 2W9SA 4M7VA 4KBNA 2DHFA 2W9HA 2DRCA 3SRRX 4M2XA 3NZCX 5JA3A 4KEBA 5HQYA 3NXYA 3JWFA 3QLWA 2O7PA 1RX4A 3ROAA 3F0UX 1MVSA 3NU0A 1M78A 4KJKA 1E26A 2OIPA 1DAJA 4LAEX 4H95A 3JVXA 1RE7A 3CL9A 3VCOA 1CZ3A 3FQCA 1DR4A 3RG9A 1DRHA 3FYVX 1RX5A 3FREX 3CD2A 5E8QA 2INQA 4OSGA 3FL9A 1SEJA 4KM2A 1JUVA 3M08A 3F0QX 1KLKA 1PDBA 2BLAA 3FQ0A 2G6VA 4QHVA 4XT5A 3QLXA 5FDAA 1U72A 4P66A 4EILA 4HA7A 4IXED 3R33A 5U26A 3QYLA 4ELHA 3SRSX 3TD8A 4EIZA 3D80A 5CCCA 4Q0DA 4ECKA 3NXOA 3F91A 3FQFA 1RB3A 4DPDA 4H96A 1KMSA 1RX9A 4G3MA 3FQOA 1DR1A 1DLSA 5HVEA 3DGAA 1RX8A 3NXVA 1DR7A 1U71A 2HXVA 1RF7A 4M7UA 5HF2X 3F0SX 3K47A 3QL3A 5HF0X 1DYJA 6DFRA 4PDJA 1M7AA 1RD7A 1DG8A 1DYIA 4I13A 4HA9A 1RG7A 4IXFX 4KJLA 2JYBA 4P68A 3EEMA 4TU5X 3DL6A 4PSTA 5JG0X 4DPHA 3D84X 1QZFA 2KGKA 3FRDX 5HSUA 4I1NA 4X5JA 5ECCA 3OCHA 2HQPA 2W3BA 2P4GA 1LY3A 2ANQA 3I8AX 3SGYA 4KL9A 1JOLA 3JTWA 4KY4A 1RA8A 1DDRA 1RA1A 3QGTA 3SA1A 1VJ3A 4ELEA 3M09A 1HFRA 3CLBA 3HJ3A 4KAKA 1HFPA 1AO8A 3K2HA 2H2QA 1DYHA 2OBCA 3FQVA 3FRFX 5CC9A 1DREA 1RH3A 2W3MA 4KD7A 4M6KA 3RO9A 1M79A 4X5GA 5HQZA 1DIUA 3K45A 4XRBA 3K74A 4ELBA 3QG2A 3GHVA 3FYWX 4QLGA 4NX6A 1J3IA 4M6JA 4KJJA 2CD2A 3FL8A 3NZBX 4KNEA 1S3WA 3FS6A 3S7AA 4LAGX 3E0BA 3SQYX 1YHOA 4PTJA 1DDSA 3SRQX 4QI9A 3JWCA 2XW7A 4OR7A 5DXVA 1HFQA 3KGYA 3DRCA 1RA2A 2W3AA 1DG7A 4H98A 1CD2A 3QLSA 4G8ZX 4LAHX 1TDRA 1DR6A 4FGHA 3I3RA 3JSUA 2HM9A 1IA4A 4HOFA 3SRWX 1DLRA 3QFXA 1BOZA 3FY8X 2BLBA 3QYOA 3TQ8A 3F0BX 2D5NA 2W3VA 1DRFA 3NRRA 3F8YA 3NTZA 1RX3A 3EEJA 3DFRA 3L3RA 5HT5A 3SR5X 1KMVA 4KM0A 1RB2A 1S3UA 1DHFA 3IA5A 4KY8A 1DISA 1DHIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H97 A;  3DG8 A;  3TQB A;  3CSE A;  3DAT A;  4HOE A;  5HUI A;  2CIG A;  3F0V X;  3GI2 A;  3SH2 A;  3NXT A;  1OHK A;  5EAJ A;  2W9T A;  5ECX A;  3KJS A;  4X5F A;  1LUD A;  3EEK A;  4PSY A;  4GH8 A;  3N0H A;  3KJR A;  4X5H A;  3HBB A;  4EIG A;  3S3V A;  4ELG A;  1RC4 A;  1BZF A;  3QL0 A;  3INV A;  3TQA A;  1DG5 A;  3QLR A;  2C2T A;  7DFR A;  3UM8 A;  3NZD A;  5HVB A;  3JW3 A;  2AZN A;  3FY9 X;  4QJC A;  4XT4 A;  4P3R A;  3DL5 A;  2W9G A;  4XT6 A;  4QLF A;  4QLE A;  3NZA X;  4IXG X;  4X5I A;  3DAU A;  2FZH A;  4XT8 A;  1DRB A;  4FGG A;  3JW5 A;  1DHJ A;  1RX7 A;  4DDR A;  4PSS A;  8DFR A;  3IRM A;  3LG4 A;  4ELF A;  5HT4 A;  2ZZA A;  2ANO A;  3IRN A;  2L28 A;  1DR3 A;  1IA2 A;  4DP3 A;  3IA4 A;  3SA2 A;  3QLZ A;  1DYR A;  3GHW A;  1J3J A;  1DR5 A;  1AI9 A;  4KYA A;  3F0X X;  2C2S A;  2GD9 A;  3JWM A;  4Q0E A;  3FRB X;  3ZPG A;  3TQ9 A;  4DFR A;  4PTH A;  3Q1H A;  4XE6 X;  1DRA A;  3NXR A;  2BL9 A;  4LEK X;  2QK8 A;  1J3K A;  3QLY A;  3EX8 A;  4NX7 A;  2D0K A;  5DFR A;  3IX9 A;  5U27 A;  3IRO A;  3KY8 A;  2LF1 A;  1RX2 A;  4Q6A A;  3F8Z A;  2BLC A;  4FHB A;  4QJZ D;  3NXX A;  3SRU X;  1AOE A;  1U70 A;  3ZPC A;  1D1G A;  1PD9 A;  4XT7 A;  4KFJ A;  1IA1 A;  3NZ6 X;  2W3W A;  1RX6 A;  3EEL A;  1MVT A;  1RX1 A;  1RA9 A;  1OHJ A;  3UM6 A;  1DR2 A;  4KLX A;  4RGC A;  3KFY A;  4CD2 A;  1ZDR A;  3SAI A;  3FRA X;  2ITH A;  5HI6 A;  1S3Y A;  4Q67 A;  4M6L A;  1VDR A;  3S9U A;  3EIG A;  4XEC X;  1S3V A;  1DF7 A;  3NZ9 X;  1JOM A;  3JWK A;  4P3Q A;  4G95 A;  3FQZ A;  2FZI A;  5HPB A;  1LY4 A;  4EJ1 A;  3OAF A;  1IA3 A;  4HOG A;  1RA3 A;  3GYF A;  2B3Z A;  3GHC A;  3UM5 A;  1PD8 A;  2FZJ A;  5HSR A;  2W9S A;  4M7V A;  4KBN A;  2DHF A;  2W9H A;  2DRC A;  3SRR X;  4M2X A;  3NZC X;  5JA3 A;  4KEB A;  5HQY A;  3NXY A;  3JWF A;  3QLW A;  2O7P A;  1RX4 A;  3ROA A;  3F0U X;  1MVS A;  3NU0 A;  1M78 A;  4KJK A;  1E26 A;  2OIP A;  1DAJ A;  4LAE X;  4H95 A;  3JVX A;  1RE7 A;  3CL9 A;  3VCO A;  1CZ3 A;  3FQC A;  1DR4 A;  3RG9 A;  1DRH A;  3FYV X;  1RX5 A;  3FRE X;  3CD2 A;  5E8Q A;  2INQ A;  4OSG A;  3FL9 A;  1SEJ A;  4KM2 A;  1JUV A;  3M08 A;  3F0Q X;  1KLK A;  1PDB A;  2BLA A;  3FQ0 A;  2G6V A;  4QHV A;  4XT5 A;  3QLX A;  5FDA A;  1U72 A;  4P66 A;  4EIL A;  4HA7 A;  4IXE D;  3R33 A;  5U26 A;  3QYL A;  4ELH A;  3SRS X;  3TD8 A;  4EIZ A;  3D80 A;  5CCC A;  4Q0D A;  4ECK A;  3NXO A;  3F91 A;  3FQF A;  1RB3 A;  4DPD A;  4H96 A;  1KMS A;  1RX9 A;  4G3M A;  3FQO A;  1DR1 A;  1DLS A;  5HVE A;  3DGA A;  1RX8 A;  3NXV A;  1DR7 A;  1U71 A;  2HXV A;  1RF7 A;  4M7U A;  5HF2 X;  3F0S X;  3K47 A;  3QL3 A;  5HF0 X;  1DYJ A;  6DFR A;  4PDJ A;  1M7A A;  1RD7 A;  1DG8 A;  1DYI A;  4I13 A;  4HA9 A;  1RG7 A;  4IXF X;  4KJL A;  2JYB A;  4P68 A;  3EEM A;  4TU5 X;  3DL6 A;  4PST A;  5JG0 X;  4DPH A;  3D84 X;  1QZF A;  2KGK A;  3FRD X;  5HSU A;  4I1N A;  4X5J A;  5ECC A;  3OCH A;  2HQP A;  2W3B A;  2P4G A;  1LY3 A;  2ANQ A;  3I8A X;  3SGY A;  4KL9 A;  1JOL A;  3JTW A;  4KY4 A;  1RA8 A;  1DDR A;  1RA1 A;  3QGT A;  3SA1 A;  1VJ3 A;  4ELE A;  3M09 A;  1HFR A;  3CLB A;  3HJ3 A;  4KAK A;  1HFP A;  1AO8 A;  3K2H A;  2H2Q A;  1DYH A;  2OBC A;  3FQV A;  3FRF X;  5CC9 A;  1DRE A;  1RH3 A;  2W3M A;  4KD7 A;  4M6K A;  3RO9 A;  1M79 A;  4X5G A;  5HQZ A;  1DIU A;  3K45 A;  4XRB A;  3K74 A;  4ELB A;  3QG2 A;  3GHV A;  3FYW X;  4QLG A;  4NX6 A;  1J3I A;  4M6J A;  4KJJ A;  2CD2 A;  3FL8 A;  3NZB X;  4KNE A;  1S3W A;  3FS6 A;  3S7A A;  4LAG X;  3E0B A;  3SQY X;  1YHO A;  4PTJ A;  1DDS A;  3SRQ X;  4QI9 A;  3JWC A;  2XW7 A;  4OR7 A;  5DXV A;  1HFQ A;  3KGY A;  3DRC A;  1RA2 A;  2W3A A;  1DG7 A;  4H98 A;  1CD2 A;  3QLS A;  4G8Z X;  4LAH X;  1TDR A;  1DR6 A;  4FGH A;  3I3R A;  3JSU A;  2HM9 A;  1IA4 A;  4HOF A;  3SRW X;  1DLR A;  3QFX A;  1BOZ A;  3FY8 X;  2BLB A;  3QYO A;  3TQ8 A;  3F0B X;  2D5N A;  2W3V A;  1DRF A;  3NRR A;  3F8Y A;  3NTZ A;  1RX3 A;  3EEJ A;  3DFR A;  3L3R A;  5HT5 A;  3SR5 X;  1KMV A;  4KM0 A;  1RB2 A;  1S3U A;  1DHF A;  3IA5 A;  4KY8 A;  1DIS A;  1DHI A; 
#chains in the Genus database with same CATH topology
 4H97 A;  3DG8 A;  3TQB A;  3CSE A;  3DAT A;  4HOE A;  5HUI A;  2CIG A;  3F0V X;  3GI2 A;  3SH2 A;  3NXT A;  1OHK A;  5EAJ A;  2W9T A;  5ECX A;  3KJS A;  4X5F A;  1LUD A;  3EEK A;  4PSY A;  4GH8 A;  3N0H A;  3KJR A;  4X5H A;  3HBB A;  4EIG A;  3S3V A;  4ELG A;  1RC4 A;  1BZF A;  3QL0 A;  3INV A;  3TQA A;  1DG5 A;  3QLR A;  2C2T A;  7DFR A;  3UM8 A;  3NZD A;  5HVB A;  3JW3 A;  2AZN A;  3FY9 X;  4QJC A;  4XT4 A;  4P3R A;  3DL5 A;  2W9G A;  4XT6 A;  4QLF A;  4QLE A;  3NZA X;  4IXG X;  4X5I A;  3DAU A;  2FZH A;  4XT8 A;  1DRB A;  4FGG A;  3JW5 A;  1DHJ A;  1RX7 A;  4DDR A;  4PSS A;  8DFR A;  3IRM A;  3LG4 A;  4ELF A;  5HT4 A;  2ZZA A;  2ANO A;  3IRN A;  2L28 A;  1DR3 A;  1IA2 A;  4DP3 A;  3IA4 A;  3SA2 A;  3QLZ A;  1DYR A;  3GHW A;  1J3J A;  1DR5 A;  1AI9 A;  4KYA A;  3F0X X;  2C2S A;  2GD9 A;  3JWM A;  4Q0E A;  3FRB X;  3ZPG A;  3TQ9 A;  4DFR A;  4PTH A;  3Q1H A;  4XE6 X;  1DRA A;  3NXR A;  2BL9 A;  4LEK X;  2QK8 A;  1J3K A;  3QLY A;  3EX8 A;  4NX7 A;  2D0K A;  5DFR A;  3IX9 A;  5U27 A;  3IRO A;  3KY8 A;  2LF1 A;  1RX2 A;  4Q6A A;  3F8Z A;  2BLC A;  4FHB A;  4QJZ D;  3NXX A;  3SRU X;  1AOE A;  1U70 A;  3ZPC A;  1D1G A;  1PD9 A;  4XT7 A;  4KFJ A;  1IA1 A;  3NZ6 X;  2W3W A;  1RX6 A;  3EEL A;  1MVT A;  1RX1 A;  1RA9 A;  1OHJ A;  3UM6 A;  1DR2 A;  4KLX A;  4RGC A;  3KFY A;  4CD2 A;  1ZDR A;  3SAI A;  3FRA X;  2ITH A;  5HI6 A;  1S3Y A;  4Q67 A;  4M6L A;  1VDR A;  3S9U A;  3EIG A;  4XEC X;  1S3V A;  1DF7 A;  3NZ9 X;  1JOM A;  3JWK A;  4P3Q A;  4G95 A;  3FQZ A;  2FZI A;  5HPB A;  1LY4 A;  4EJ1 A;  3OAF A;  1IA3 A;  4HOG A;  1RA3 A;  3GYF A;  2B3Z A;  3GHC A;  3UM5 A;  1PD8 A;  2FZJ A;  5HSR A;  2W9S A;  4M7V A;  4KBN A;  2DHF A;  2W9H A;  2DRC A;  3SRR X;  4M2X A;  3NZC X;  5JA3 A;  4KEB A;  5HQY A;  3NXY A;  3JWF A;  3QLW A;  2O7P A;  1RX4 A;  3ROA A;  3F0U X;  1MVS A;  3NU0 A;  1M78 A;  4KJK A;  1E26 A;  2OIP A;  1DAJ A;  4LAE X;  4H95 A;  3JVX A;  1RE7 A;  3CL9 A;  3VCO A;  1CZ3 A;  3FQC A;  1DR4 A;  3RG9 A;  1DRH A;  3FYV X;  1RX5 A;  3FRE X;  3CD2 A;  5E8Q A;  2INQ A;  4OSG A;  3FL9 A;  1SEJ A;  4KM2 A;  1JUV A;  3M08 A;  3F0Q X;  1KLK A;  1PDB A;  2BLA A;  3FQ0 A;  2G6V A;  4QHV A;  4XT5 A;  3QLX A;  5FDA A;  1U72 A;  4P66 A;  4EIL A;  4HA7 A;  4IXE D;  3R33 A;  5U26 A;  3QYL A;  4ELH A;  3SRS X;  3TD8 A;  4EIZ A;  3D80 A;  5CCC A;  4Q0D A;  4ECK A;  3NXO A;  3F91 A;  3FQF A;  1RB3 A;  4DPD A;  4H96 A;  1KMS A;  1RX9 A;  4G3M A;  3FQO A;  1DR1 A;  1DLS A;  5HVE A;  3DGA A;  1RX8 A;  3NXV A;  1DR7 A;  1U71 A;  2HXV A;  1RF7 A;  4M7U A;  5HF2 X;  3F0S X;  3K47 A;  3QL3 A;  5HF0 X;  1DYJ A;  6DFR A;  4PDJ A;  1M7A A;  1RD7 A;  1DG8 A;  1DYI A;  4I13 A;  4HA9 A;  1RG7 A;  4IXF X;  4KJL A;  2JYB A;  4P68 A;  3EEM A;  4TU5 X;  3DL6 A;  4PST A;  5JG0 X;  4DPH A;  3D84 X;  1QZF A;  2KGK A;  3FRD X;  5HSU A;  4I1N A;  4X5J A;  5ECC A;  3OCH A;  2HQP A;  2W3B A;  2P4G A;  1LY3 A;  2ANQ A;  3I8A X;  3SGY A;  4KL9 A;  1JOL A;  3JTW A;  4KY4 A;  1RA8 A;  1DDR A;  1RA1 A;  3QGT A;  3SA1 A;  1VJ3 A;  4ELE A;  3M09 A;  1HFR A;  3CLB A;  3HJ3 A;  4KAK A;  1HFP A;  1AO8 A;  3K2H A;  2H2Q A;  1DYH A;  2OBC A;  3FQV A;  3FRF X;  5CC9 A;  1DRE A;  1RH3 A;  2W3M A;  4KD7 A;  4M6K A;  3RO9 A;  1M79 A;  4X5G A;  5HQZ A;  1DIU A;  3K45 A;  4XRB A;  3K74 A;  4ELB A;  3QG2 A;  3GHV A;  3FYW X;  4QLG A;  4NX6 A;  1J3I A;  4M6J A;  4KJJ A;  2CD2 A;  3FL8 A;  3NZB X;  4KNE A;  1S3W A;  3FS6 A;  3S7A A;  4LAG X;  3E0B A;  3SQY X;  1YHO A;  4PTJ A;  1DDS A;  3SRQ X;  4QI9 A;  3JWC A;  2XW7 A;  4OR7 A;  5DXV A;  1HFQ A;  3KGY A;  3DRC A;  1RA2 A;  2W3A A;  1DG7 A;  4H98 A;  1CD2 A;  3QLS A;  4G8Z X;  4LAH X;  1TDR A;  1DR6 A;  4FGH A;  3I3R A;  3JSU A;  2HM9 A;  1IA4 A;  4HOF A;  3SRW X;  1DLR A;  3QFX A;  1BOZ A;  3FY8 X;  2BLB A;  3QYO A;  3TQ8 A;  3F0B X;  2D5N A;  2W3V A;  1DRF A;  3NRR A;  3F8Y A;  3NTZ A;  1RX3 A;  3EEJ A;  3DFR A;  3L3R A;  5HT5 A;  3SR5 X;  1KMV A;  4KM0 A;  1RB2 A;  1S3U A;  1DHF A;  3IA5 A;  4KY8 A;  1DIS A;  1DHI A; 
#chains in the Genus database with same CATH homology
 4H97 A;  3DG8 A;  3TQB A;  3CSE A;  3DAT A;  4HOE A;  5HUI A;  2CIG A;  3F0V X;  3GI2 A;  3SH2 A;  3NXT A;  1OHK A;  5EAJ A;  2W9T A;  5ECX A;  3KJS A;  4X5F A;  1LUD A;  3EEK A;  4PSY A;  4GH8 A;  3N0H A;  3KJR A;  4X5H A;  3HBB A;  4EIG A;  3S3V A;  4ELG A;  1RC4 A;  1BZF A;  3QL0 A;  3INV A;  3TQA A;  1DG5 A;  3QLR A;  2C2T A;  7DFR A;  3UM8 A;  3NZD A;  5HVB A;  3JW3 A;  2AZN A;  3FY9 X;  4QJC A;  4XT4 A;  4P3R A;  3DL5 A;  2W9G A;  4XT6 A;  4QLF A;  4QLE A;  3NZA X;  4IXG X;  4X5I A;  3DAU A;  2FZH A;  4XT8 A;  1DRB A;  4FGG A;  3JW5 A;  1DHJ A;  1RX7 A;  4DDR A;  4PSS A;  8DFR A;  3IRM A;  3LG4 A;  4ELF A;  5HT4 A;  2ZZA A;  2ANO A;  3IRN A;  2L28 A;  1DR3 A;  1IA2 A;  4DP3 A;  3IA4 A;  3SA2 A;  3QLZ A;  1DYR A;  3GHW A;  1J3J A;  1DR5 A;  1AI9 A;  4KYA A;  3F0X X;  2C2S A;  2GD9 A;  3JWM A;  4Q0E A;  3FRB X;  3ZPG A;  3TQ9 A;  4DFR A;  4PTH A;  3Q1H A;  4XE6 X;  1DRA A;  3NXR A;  2BL9 A;  4LEK X;  2QK8 A;  1J3K A;  3QLY A;  3EX8 A;  4NX7 A;  2D0K A;  5DFR A;  3IX9 A;  5U27 A;  3IRO A;  3KY8 A;  2LF1 A;  1RX2 A;  4Q6A A;  3F8Z A;  2BLC A;  4FHB A;  4QJZ D;  3NXX A;  3SRU X;  1AOE A;  1U70 A;  3ZPC A;  1D1G A;  1PD9 A;  4XT7 A;  4KFJ A;  1IA1 A;  3NZ6 X;  2W3W A;  1RX6 A;  3EEL A;  1MVT A;  1RX1 A;  1RA9 A;  1OHJ A;  3UM6 A;  1DR2 A;  4KLX A;  4RGC A;  3KFY A;  4CD2 A;  1ZDR A;  3SAI A;  3FRA X;  2ITH A;  5HI6 A;  1S3Y A;  4Q67 A;  4M6L A;  1VDR A;  3S9U A;  3EIG A;  4XEC X;  1S3V A;  1DF7 A;  3NZ9 X;  1JOM A;  3JWK A;  4P3Q A;  4G95 A;  3FQZ A;  2FZI A;  5HPB A;  1LY4 A;  4EJ1 A;  3OAF A;  1IA3 A;  4HOG A;  1RA3 A;  3GYF A;  2B3Z A;  3GHC A;  3UM5 A;  1PD8 A;  2FZJ A;  5HSR A;  2W9S A;  4M7V A;  4KBN A;  2DHF A;  2W9H A;  2DRC A;  3SRR X;  4M2X A;  3NZC X;  5JA3 A;  4KEB A;  5HQY A;  3NXY A;  3JWF A;  3QLW A;  2O7P A;  1RX4 A;  3ROA A;  3F0U X;  1MVS A;  3NU0 A;  1M78 A;  4KJK A;  1E26 A;  2OIP A;  1DAJ A;  4LAE X;  4H95 A;  3JVX A;  1RE7 A;  3CL9 A;  3VCO A;  1CZ3 A;  3FQC A;  1DR4 A;  3RG9 A;  1DRH A;  3FYV X;  1RX5 A;  3FRE X;  3CD2 A;  5E8Q A;  2INQ A;  4OSG A;  3FL9 A;  1SEJ A;  4KM2 A;  1JUV A;  3M08 A;  3F0Q X;  1KLK A;  1PDB A;  2BLA A;  3FQ0 A;  2G6V A;  4QHV A;  4XT5 A;  3QLX A;  5FDA A;  1U72 A;  4P66 A;  4EIL A;  4HA7 A;  4IXE D;  3R33 A;  5U26 A;  3QYL A;  4ELH A;  3SRS X;  3TD8 A;  4EIZ A;  3D80 A;  5CCC A;  4Q0D A;  4ECK A;  3NXO A;  3F91 A;  3FQF A;  1RB3 A;  4DPD A;  4H96 A;  1KMS A;  1RX9 A;  4G3M A;  3FQO A;  1DR1 A;  1DLS A;  5HVE A;  3DGA A;  1RX8 A;  3NXV A;  1DR7 A;  1U71 A;  2HXV A;  1RF7 A;  4M7U A;  5HF2 X;  3F0S X;  3K47 A;  3QL3 A;  5HF0 X;  1DYJ A;  6DFR A;  4PDJ A;  1M7A A;  1RD7 A;  1DG8 A;  1DYI A;  4I13 A;  4HA9 A;  1RG7 A;  4IXF X;  4KJL A;  2JYB A;  4P68 A;  3EEM A;  4TU5 X;  3DL6 A;  4PST A;  5JG0 X;  4DPH A;  3D84 X;  1QZF A;  2KGK A;  3FRD X;  5HSU A;  4I1N A;  4X5J A;  5ECC A;  3OCH A;  2HQP A;  2W3B A;  2P4G A;  1LY3 A;  2ANQ A;  3I8A X;  3SGY A;  4KL9 A;  1JOL A;  3JTW A;  4KY4 A;  1RA8 A;  1DDR A;  1RA1 A;  3QGT A;  3SA1 A;  1VJ3 A;  4ELE A;  3M09 A;  1HFR A;  3CLB A;  3HJ3 A;  4KAK A;  1HFP A;  1AO8 A;  3K2H A;  2H2Q A;  1DYH A;  2OBC A;  3FQV A;  3FRF X;  5CC9 A;  1DRE A;  1RH3 A;  2W3M A;  4KD7 A;  4M6K A;  3RO9 A;  1M79 A;  4X5G A;  5HQZ A;  1DIU A;  3K45 A;  4XRB A;  3K74 A;  4ELB A;  3QG2 A;  3GHV A;  3FYW X;  4QLG A;  4NX6 A;  1J3I A;  4M6J A;  4KJJ A;  2CD2 A;  3FL8 A;  3NZB X;  4KNE A;  1S3W A;  3FS6 A;  3S7A A;  4LAG X;  3E0B A;  3SQY X;  1YHO A;  4PTJ A;  1DDS A;  3SRQ X;  4QI9 A;  3JWC A;  2XW7 A;  4OR7 A;  5DXV A;  1HFQ A;  3KGY A;  3DRC A;  1RA2 A;  2W3A A;  1DG7 A;  4H98 A;  1CD2 A;  3QLS A;  4G8Z X;  4LAH X;  1TDR A;  1DR6 A;  4FGH A;  3I3R A;  3JSU A;  2HM9 A;  1IA4 A;  4HOF A;  3SRW X;  1DLR A;  3QFX A;  1BOZ A;  3FY8 X;  2BLB A;  3QYO A;  3TQ8 A;  3F0B X;  2D5N A;  2W3V A;  1DRF A;  3NRR A;  3F8Y A;  3NTZ A;  1RX3 A;  3EEJ A;  3DFR A;  3L3R A;  5HT5 A;  3SR5 X;  1KMV A;  4KM0 A;  1RB2 A;  1S3U A;  1DHF A;  3IA5 A;  4KY8 A;  1DIS A;  1DHI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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