4Q67A

Staphylococcus aureus f98y mutant dihydrofolate reductase complexed with nadph
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLYEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
source organism Staphylococcus aureus muf168
publication title Protein design algorithms predict viable resistance to an experimental antifolate.
pubmed doi rcsb
molecule keywords Dihydrofolate reductase
total genus 40
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-04-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4q67A00
3HJ3A 1S3YA 2BLBA 3FYWX 1CD2A 3EX8A 3F0UX 3FS6A 1DHIA 4H97A 3D84X 5HPBA 4IXFX 1PD8A 1DLSA 3GHCA 8DFRA 3FRFX 4XE6X 3FQZA 5DXVA 3F91A 3SR5X 3TQ9A 3JWMA 4RGCA 5U26A 1JOMA 3KY8A 1VDRA 4QHVA 4H96A 4PTHA 3SAIA 3LG4A 5DFRA 3TD8A 4DFRA 2CIGA 3DL5A 3DAUA 2AZNA 3HBBA 5HUIA 1DLRA 4ELBA 3IRMA 1ZDRA 4KNEA 3NZ9X 1KLKA 4M7UA 4Q6AA 5HSUA 3Q1HA 5HT4A 4ELEA 4KM2A 4FGGA 3DG8A 3CSEA 2W3BA 1DRFA 4X5GA 2W3VA 1RX2A 3NXYA 4PDJA 3D80A 1RX4A 2HQPA 3FRBX 3FRAX 1DRHA 3FQCA 4M7VA 4XECX 3NTZA 3SRWX 3EELA 3SH2A 2DHFA 4Q0DA 3JTWA 4QJZD 2LF1A 4NX7A 4ELFA 3F8ZA 1RH3A 3INVA 3QLWA 3F0BX 3EEMA 1DYJA 5HI6A 1U71A 4M6LA 5CCCA 3NXOA 2OBCA 1RX1A 4KD7A 2C2SA 4H98A 4CD2A 3M09A 2INQA 3K2HA 4X5JA 3CL9A 1DR2A 3NZCX 3KFYA 1OHJA 1VJ3A 4KY4A 4H95A 3F0XX 4XT6A 4Q67A 4KL9A 4M6JA 1RA8A 4DP3A 2OIPA 2W3WA 4PSSA 4P66A 3FYVX 1RX8A 3SRSX 3DFRA 4ELGA 4FHBA 1DISA 3EEKA 4PSTA 4G8ZX 1RX3A 1PDBA 4KM0A 3ZPGA 2BLAA 2W3AA 3NXRA 4PSYA 3S9UA 3QLYA 2H2QA 2CD2A 3UM5A 4M2XA 2O7PA 3FL9A 1MVSA 6DFRA 3SRRX 5E8QA 3FQVA 4QLFA 2W9SA 4TU5X 1DDSA 1DF7A 3FY9X 3FY8X 2KGKA 5U27A 1OHKA 1DAJA 4DDRA 5HVBA 1IA3A 4G3MA 5HQYA 3JWCA 1RA9A 1RA1A 4FGHA 3ROAA 3RG9A 3OAFA 3QLSA 3S3VA 1DDRA 3RO9A 1TDRA 1DIUA 4KJLA 1DR5A 3QGTA 1JUVA 3QLRA 4IXED 4KBNA 3CD2A 1QZFA 1RB3A 1M78A 3JW5A 2FZHA 4I1NA 7DFRA 3FQOA 3F0SX 1DR1A 3KGYA 1IA1A 2DRCA 1JOLA 5HT5A 4HA9A 3DRCA 1U70A 3IA4A 4DPHA 1LY4A 1BZFA 2HXVA 2ANQA 1BOZA 3JVXA 1DHJA 5EAJA 3DL6A 4OR7A 4KEBA 4PTJA 4XT7A 4QI9A 1RF7A 4KJKA 3F8YA 3IRNA 1RX9A 4LEKX 2QK8A 3GHVA 3SGYA 3KJSA 3JWKA 4KFJA 4P3QA 4ECKA 3ZPCA 2W9HA 1J3IA 3UM6A 2W9GA 2GD9A 4EJ1A 4LAHX 1KMSA 3L3RA 1HFQA 3QL0A 3NZDA 4P68A 1HFRA 4G95A 1RE7A 2XW7A 3M08A 1J3JA 3GI2A 4Q0EA 3TQAA 5HSRA 4EILA 3DATA 1LY3A 3NZBX 4XRBA 3QG2A 1IA4A 3QL3A 3TQBA 4M6KA 3SQYX 1MVTA 3EIGA 3I3RA 1DYRA 1RA2A 4ELHA 3NU0A 1S3WA 3NXVA 2HM9A 3QLZA 3DGAA 3R33A 4HOFA 5HVEA 1J3KA 1RD7A 2JYBA 4DPDA 4XT5A 4KJJA 3N0HA 4QLGA 3F0VX 3SA2A 3E0BA 4LAGX 3NXXA 3QYOA 1RA3A 3VCOA 3FREX 4P3RA 1PD9A 5HF0X 4LAEX 3NRRA 1AO8A 3OCHA 3QFXA 4XT4A 4QJCA 1M79A 1RB2A 4EIGA 3UM8A 3QYLA 4XT8A 3GHWA 1YHOA 4OSGA 3NZAX 1DG5A 1KMVA 3CLBA 2C2TA 3GYFA 3K47A 4HOEA 1RG7A 2BL9A 3FRDX 1E26A 3K45A 4QLEA 1AI9A 5HQZA 5FDAA 4NX6A 1S3VA 2ZZAA 1M7AA 1IA2A 2L28A 3JWFA 2B3ZA 1D1GA 2FZIA 4KLXA 1U72A 4KYAA 3SRUX 1DR4A 3QLXA 3FL8A 3NXTA 1DR7A 1SEJA 3EEJA 1RX6A 1DG7A 4I13A 4X5IA 3JSUA 3NZ6X 1DYHA 2G6VA 4IXGX 1CZ3A 1DYIA 2FZJA 1DRAA 2ANOA 4KAKA 5HF2X 1DREA 3TQ8A 2W3MA 3SRQX 2P4GA 3S7AA 3FQ0A 3JW3A 4X5HA 1HFPA 1DG8A 1RC4A 2ITHA 1DHFA 4HA7A 1RX5A 2W9TA 4EIZA 5JA3A 3SA1A 1DR6A 3K74A 4HOGA 2BLCA 3IX9A 2D0KA 1DRBA 1RX7A 3FQFA 4GH8A 3F0QX 1DR3A 2D5NA 3IA5A 1LUDA 4KY8A 5ECXA 4X5FA 3I8AX 1AOEA 1S3UA 5CC9A 3KJRA 5JG0X 5ECCA 3IROA
chains in the Genus database with same CATH superfamily
3HJ3A 1S3YA 2BLBA 3FYWX 1CD2A 3EX8A 3F0UX 3FS6A 1DHIA 4H97A 3D84X 5HPBA 4IXFX 1PD8A 1DLSA 3GHCA 8DFRA 3FRFX 4XE6X 3FQZA 5DXVA 3F91A 3SR5X 3TQ9A 3JWMA 4RGCA 5U26A 1JOMA 3KY8A 1VDRA 4QHVA 4H96A 4PTHA 3SAIA 3LG4A 5DFRA 3TD8A 4DFRA 2CIGA 3DL5A 3DAUA 2AZNA 3HBBA 5HUIA 1DLRA 4ELBA 3IRMA 1ZDRA 4KNEA 3NZ9X 1KLKA 4M7UA 4Q6AA 5HSUA 3Q1HA 5HT4A 4ELEA 4KM2A 4FGGA 3DG8A 3CSEA 2W3BA 1DRFA 4X5GA 2W3VA 1RX2A 3NXYA 4PDJA 3D80A 1RX4A 2HQPA 3FRBX 3FRAX 1DRHA 3FQCA 4M7VA 4XECX 3NTZA 3SRWX 3EELA 3SH2A 2DHFA 4Q0DA 3JTWA 4QJZD 2LF1A 4NX7A 4ELFA 3F8ZA 1RH3A 3INVA 3QLWA 3F0BX 3EEMA 1DYJA 5HI6A 1U71A 4M6LA 5CCCA 3NXOA 2OBCA 1RX1A 4KD7A 2C2SA 4H98A 4CD2A 3M09A 2INQA 3K2HA 4X5JA 3CL9A 1DR2A 3NZCX 3KFYA 1OHJA 1VJ3A 4KY4A 4H95A 3F0XX 4XT6A 4Q67A 4KL9A 4M6JA 1RA8A 4DP3A 2OIPA 2W3WA 4PSSA 4P66A 3FYVX 1RX8A 3SRSX 3DFRA 4ELGA 4FHBA 1DISA 3EEKA 4PSTA 4G8ZX 1RX3A 1PDBA 4KM0A 3ZPGA 2BLAA 2W3AA 3NXRA 4PSYA 3S9UA 3QLYA 2H2QA 2CD2A 3UM5A 4M2XA 2O7PA 3FL9A 1MVSA 6DFRA 3SRRX 5E8QA 3FQVA 4QLFA 2W9SA 4TU5X 1DDSA 1DF7A 3FY9X 3FY8X 2KGKA 5U27A 1OHKA 1DAJA 4DDRA 5HVBA 1IA3A 4G3MA 5HQYA 3JWCA 1RA9A 1RA1A 4FGHA 3ROAA 3RG9A 3OAFA 3QLSA 3S3VA 1DDRA 3RO9A 1TDRA 1DIUA 4KJLA 1DR5A 3QGTA 1JUVA 3QLRA 4IXED 4KBNA 3CD2A 1QZFA 1RB3A 1M78A 3JW5A 2FZHA 4I1NA 7DFRA 3FQOA 3F0SX 1DR1A 3KGYA 1IA1A 2DRCA 1JOLA 5HT5A 4HA9A 3DRCA 1U70A 3IA4A 4DPHA 1LY4A 1BZFA 2HXVA 2ANQA 1BOZA 3JVXA 1DHJA 5EAJA 3DL6A 4OR7A 4KEBA 4PTJA 4XT7A 4QI9A 1RF7A 4KJKA 3F8YA 3IRNA 1RX9A 4LEKX 2QK8A 3GHVA 3SGYA 3KJSA 3JWKA 4KFJA 4P3QA 4ECKA 3ZPCA 2W9HA 1J3IA 3UM6A 2W9GA 2GD9A 4EJ1A 4LAHX 1KMSA 3L3RA 1HFQA 3QL0A 3NZDA 4P68A 1HFRA 4G95A 1RE7A 2XW7A 3M08A 1J3JA 3GI2A 4Q0EA 3TQAA 5HSRA 4EILA 3DATA 1LY3A 3NZBX 4XRBA 3QG2A 1IA4A 3QL3A 3TQBA 4M6KA 3SQYX 1MVTA 3EIGA 3I3RA 1DYRA 1RA2A 4ELHA 3NU0A 1S3WA 3NXVA 2HM9A 3QLZA 3DGAA 3R33A 4HOFA 5HVEA 1J3KA 1RD7A 2JYBA 4DPDA 4XT5A 4KJJA 3N0HA 4QLGA 3F0VX 3SA2A 3E0BA 4LAGX 3NXXA 3QYOA 1RA3A 3VCOA 3FREX 4P3RA 1PD9A 5HF0X 4LAEX 3NRRA 1AO8A 3OCHA 3QFXA 4XT4A 4QJCA 1M79A 1RB2A 4EIGA 3UM8A 3QYLA 4XT8A 3GHWA 1YHOA 4OSGA 3NZAX 1DG5A 1KMVA 3CLBA 2C2TA 3GYFA 3K47A 4HOEA 1RG7A 2BL9A 3FRDX 1E26A 3K45A 4QLEA 1AI9A 5HQZA 5FDAA 4NX6A 1S3VA 2ZZAA 1M7AA 1IA2A 2L28A 3JWFA 2B3ZA 1D1GA 2FZIA 4KLXA 1U72A 4KYAA 3SRUX 1DR4A 3QLXA 3FL8A 3NXTA 1DR7A 1SEJA 3EEJA 1RX6A 1DG7A 4I13A 4X5IA 3JSUA 3NZ6X 1DYHA 2G6VA 4IXGX 1CZ3A 1DYIA 2FZJA 1DRAA 2ANOA 4KAKA 5HF2X 1DREA 3TQ8A 2W3MA 3SRQX 2P4GA 3S7AA 3FQ0A 3JW3A 4X5HA 1HFPA 1DG8A 1RC4A 2ITHA 1DHFA 4HA7A 1RX5A 2W9TA 4EIZA 5JA3A 3SA1A 1DR6A 3K74A 4HOGA 2BLCA 3IX9A 2D0KA 1DRBA 1RX7A 3FQFA 4GH8A 3F0QX 1DR3A 2D5NA 3IA5A 1LUDA 4KY8A 5ECXA 4X5FA 3I8AX 1AOEA 1S3UA 5CC9A 3KJRA 5JG0X 5ECCA 3IROA
chains in the Genus database with same CATH topology
3HJ3A 1S3YA 2BLBA 3FYWX 1CD2A 3EX8A 3F0UX 3FS6A 1DHIA 4H97A 3D84X 5HPBA 4IXFX 1PD8A 1DLSA 3GHCA 8DFRA 3FRFX 4XE6X 3FQZA 5DXVA 3F91A 3SR5X 3TQ9A 3JWMA 4RGCA 5U26A 1JOMA 3KY8A 1VDRA 4QHVA 4H96A 4PTHA 3SAIA 3LG4A 5DFRA 3TD8A 4DFRA 2CIGA 3DL5A 3DAUA 2AZNA 3HBBA 5HUIA 1DLRA 4ELBA 3IRMA 1ZDRA 4KNEA 3NZ9X 1KLKA 4M7UA 4Q6AA 5HSUA 3Q1HA 5HT4A 4ELEA 4KM2A 4FGGA 3DG8A 3CSEA 2W3BA 1DRFA 4X5GA 2W3VA 1RX2A 3NXYA 4PDJA 3D80A 1RX4A 2HQPA 3FRBX 3FRAX 1DRHA 3FQCA 4M7VA 4XECX 3NTZA 3SRWX 3EELA 3SH2A 2DHFA 4Q0DA 3JTWA 4QJZD 2LF1A 4NX7A 4ELFA 3F8ZA 1RH3A 3INVA 3QLWA 3F0BX 3EEMA 1DYJA 5HI6A 1U71A 4M6LA 5CCCA 3NXOA 2OBCA 1RX1A 4KD7A 2C2SA 4H98A 4CD2A 3M09A 2INQA 3K2HA 4X5JA 3CL9A 1DR2A 3NZCX 3KFYA 1OHJA 1VJ3A 4KY4A 4H95A 3F0XX 4XT6A 4Q67A 4KL9A 4M6JA 1RA8A 4DP3A 2OIPA 2W3WA 4PSSA 4P66A 3FYVX 1RX8A 3SRSX 3DFRA 4ELGA 4FHBA 1DISA 3EEKA 4PSTA 4G8ZX 1RX3A 1PDBA 4KM0A 3ZPGA 2BLAA 2W3AA 3NXRA 4PSYA 3S9UA 3QLYA 2H2QA 2CD2A 3UM5A 4M2XA 2O7PA 3FL9A 1MVSA 6DFRA 3SRRX 5E8QA 3FQVA 4QLFA 2W9SA 4TU5X 1DDSA 1DF7A 3FY9X 3FY8X 2KGKA 5U27A 1OHKA 1DAJA 4DDRA 5HVBA 1IA3A 4G3MA 5HQYA 3JWCA 1RA9A 1RA1A 4FGHA 3ROAA 3RG9A 3OAFA 3QLSA 3S3VA 1DDRA 3RO9A 1TDRA 1DIUA 4KJLA 1DR5A 3QGTA 1JUVA 3QLRA 4IXED 4KBNA 3CD2A 1QZFA 1RB3A 1M78A 3JW5A 2FZHA 4I1NA 7DFRA 3FQOA 3F0SX 1DR1A 3KGYA 1IA1A 2DRCA 1JOLA 5HT5A 4HA9A 3DRCA 1U70A 3IA4A 4DPHA 1LY4A 1BZFA 2HXVA 2ANQA 1BOZA 3JVXA 1DHJA 5EAJA 3DL6A 4OR7A 4KEBA 4PTJA 4XT7A 4QI9A 1RF7A 4KJKA 3F8YA 3IRNA 1RX9A 4LEKX 2QK8A 3GHVA 3SGYA 3KJSA 3JWKA 4KFJA 4P3QA 4ECKA 3ZPCA 2W9HA 1J3IA 3UM6A 2W9GA 2GD9A 4EJ1A 4LAHX 1KMSA 3L3RA 1HFQA 3QL0A 3NZDA 4P68A 1HFRA 4G95A 1RE7A 2XW7A 3M08A 1J3JA 3GI2A 4Q0EA 3TQAA 5HSRA 4EILA 3DATA 1LY3A 3NZBX 4XRBA 3QG2A 1IA4A 3QL3A 3TQBA 4M6KA 3SQYX 1MVTA 3EIGA 3I3RA 1DYRA 1RA2A 4ELHA 3NU0A 1S3WA 3NXVA 2HM9A 3QLZA 3DGAA 3R33A 4HOFA 5HVEA 1J3KA 1RD7A 2JYBA 4DPDA 4XT5A 4KJJA 3N0HA 4QLGA 3F0VX 3SA2A 3E0BA 4LAGX 3NXXA 3QYOA 1RA3A 3VCOA 3FREX 4P3RA 1PD9A 5HF0X 4LAEX 3NRRA 1AO8A 3OCHA 3QFXA 4XT4A 4QJCA 1M79A 1RB2A 4EIGA 3UM8A 3QYLA 4XT8A 3GHWA 1YHOA 4OSGA 3NZAX 1DG5A 1KMVA 3CLBA 2C2TA 3GYFA 3K47A 4HOEA 1RG7A 2BL9A 3FRDX 1E26A 3K45A 4QLEA 1AI9A 5HQZA 5FDAA 4NX6A 1S3VA 2ZZAA 1M7AA 1IA2A 2L28A 3JWFA 2B3ZA 1D1GA 2FZIA 4KLXA 1U72A 4KYAA 3SRUX 1DR4A 3QLXA 3FL8A 3NXTA 1DR7A 1SEJA 3EEJA 1RX6A 1DG7A 4I13A 4X5IA 3JSUA 3NZ6X 1DYHA 2G6VA 4IXGX 1CZ3A 1DYIA 2FZJA 1DRAA 2ANOA 4KAKA 5HF2X 1DREA 3TQ8A 2W3MA 3SRQX 2P4GA 3S7AA 3FQ0A 3JW3A 4X5HA 1HFPA 1DG8A 1RC4A 2ITHA 1DHFA 4HA7A 1RX5A 2W9TA 4EIZA 5JA3A 3SA1A 1DR6A 3K74A 4HOGA 2BLCA 3IX9A 2D0KA 1DRBA 1RX7A 3FQFA 4GH8A 3F0QX 1DR3A 2D5NA 3IA5A 1LUDA 4KY8A 5ECXA 4X5FA 3I8AX 1AOEA 1S3UA 5CC9A 3KJRA 5JG0X 5ECCA 3IROA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HJ3 A;  1S3Y A;  2BLB A;  3FYW X;  1CD2 A;  3EX8 A;  3F0U X;  3FS6 A;  1DHI A;  4H97 A;  3D84 X;  5HPB A;  4IXF X;  1PD8 A;  1DLS A;  3GHC A;  8DFR A;  3FRF X;  4XE6 X;  3FQZ A;  5DXV A;  3F91 A;  3SR5 X;  3TQ9 A;  3JWM A;  4RGC A;  5U26 A;  1JOM A;  3KY8 A;  1VDR A;  4QHV A;  4H96 A;  4PTH A;  3SAI A;  3LG4 A;  5DFR A;  3TD8 A;  4DFR A;  2CIG A;  3DL5 A;  3DAU A;  2AZN A;  3HBB A;  5HUI A;  1DLR A;  4ELB A;  3IRM A;  1ZDR A;  4KNE A;  3NZ9 X;  1KLK A;  4M7U A;  4Q6A A;  5HSU A;  3Q1H A;  5HT4 A;  4ELE A;  4KM2 A;  4FGG A;  3DG8 A;  3CSE A;  2W3B A;  1DRF A;  4X5G A;  2W3V A;  1RX2 A;  3NXY A;  4PDJ A;  3D80 A;  1RX4 A;  2HQP A;  3FRB X;  3FRA X;  1DRH A;  3FQC A;  4M7V A;  4XEC X;  3NTZ A;  3SRW X;  3EEL A;  3SH2 A;  2DHF A;  4Q0D A;  3JTW A;  4QJZ D;  2LF1 A;  4NX7 A;  4ELF A;  3F8Z A;  1RH3 A;  3INV A;  3QLW A;  3F0B X;  3EEM A;  1DYJ A;  5HI6 A;  1U71 A;  4M6L A;  5CCC A;  3NXO A;  2OBC A;  1RX1 A;  4KD7 A;  2C2S A;  4H98 A;  4CD2 A;  3M09 A;  2INQ A;  3K2H A;  4X5J A;  3CL9 A;  1DR2 A;  3NZC X;  3KFY A;  1OHJ A;  1VJ3 A;  4KY4 A;  4H95 A;  3F0X X;  4XT6 A;  4Q67 A;  4KL9 A;  4M6J A;  1RA8 A;  4DP3 A;  2OIP A;  2W3W A;  4PSS A;  4P66 A;  3FYV X;  1RX8 A;  3SRS X;  3DFR A;  4ELG A;  4FHB A;  1DIS A;  3EEK A;  4PST A;  4G8Z X;  1RX3 A;  1PDB A;  4KM0 A;  3ZPG A;  2BLA A;  2W3A A;  3NXR A;  4PSY A;  3S9U A;  3QLY A;  2H2Q A;  2CD2 A;  3UM5 A;  4M2X A;  2O7P A;  3FL9 A;  1MVS A;  6DFR A;  3SRR X;  5E8Q A;  3FQV A;  4QLF A;  2W9S A;  4TU5 X;  1DDS A;  1DF7 A;  3FY9 X;  3FY8 X;  2KGK A;  5U27 A;  1OHK A;  1DAJ A;  4DDR A;  5HVB A;  1IA3 A;  4G3M A;  5HQY A;  3JWC A;  1RA9 A;  1RA1 A;  4FGH A;  3ROA A;  3RG9 A;  3OAF A;  3QLS A;  3S3V A;  1DDR A;  3RO9 A;  1TDR A;  1DIU A;  4KJL A;  1DR5 A;  3QGT A;  1JUV A;  3QLR A;  4IXE D;  4KBN A;  3CD2 A;  1QZF A;  1RB3 A;  1M78 A;  3JW5 A;  2FZH A;  4I1N A;  7DFR A;  3FQO A;  3F0S X;  1DR1 A;  3KGY A;  1IA1 A;  2DRC A;  1JOL A;  5HT5 A;  4HA9 A;  3DRC A;  1U70 A;  3IA4 A;  4DPH A;  1LY4 A;  1BZF A;  2HXV A;  2ANQ A;  1BOZ A;  3JVX A;  1DHJ A;  5EAJ A;  3DL6 A;  4OR7 A;  4KEB A;  4PTJ A;  4XT7 A;  4QI9 A;  1RF7 A;  4KJK A;  3F8Y A;  3IRN A;  1RX9 A;  4LEK X;  2QK8 A;  3GHV A;  3SGY A;  3KJS A;  3JWK A;  4KFJ A;  4P3Q A;  4ECK A;  3ZPC A;  2W9H A;  1J3I A;  3UM6 A;  2W9G A;  2GD9 A;  4EJ1 A;  4LAH X;  1KMS A;  3L3R A;  1HFQ A;  3QL0 A;  3NZD A;  4P68 A;  1HFR A;  4G95 A;  1RE7 A;  2XW7 A;  3M08 A;  1J3J A;  3GI2 A;  4Q0E A;  3TQA A;  5HSR A;  4EIL A;  3DAT A;  1LY3 A;  3NZB X;  4XRB A;  3QG2 A;  1IA4 A;  3QL3 A;  3TQB A;  4M6K A;  3SQY X;  1MVT A;  3EIG A;  3I3R A;  1DYR A;  1RA2 A;  4ELH A;  3NU0 A;  1S3W A;  3NXV A;  2HM9 A;  3QLZ A;  3DGA A;  3R33 A;  4HOF A;  5HVE A;  1J3K A;  1RD7 A;  2JYB A;  4DPD A;  4XT5 A;  4KJJ A;  3N0H A;  4QLG A;  3F0V X;  3SA2 A;  3E0B A;  4LAG X;  3NXX A;  3QYO A;  1RA3 A;  3VCO A;  3FRE X;  4P3R A;  1PD9 A;  5HF0 X;  4LAE X;  3NRR A;  1AO8 A;  3OCH A;  3QFX A;  4XT4 A;  4QJC A;  1M79 A;  1RB2 A;  4EIG A;  3UM8 A;  3QYL A;  4XT8 A;  3GHW A;  1YHO A;  4OSG A;  3NZA X;  1DG5 A;  1KMV A;  3CLB A;  2C2T A;  3GYF A;  3K47 A;  4HOE A;  1RG7 A;  2BL9 A;  3FRD X;  1E26 A;  3K45 A;  4QLE A;  1AI9 A;  5HQZ A;  5FDA A;  4NX6 A;  1S3V A;  2ZZA A;  1M7A A;  1IA2 A;  2L28 A;  3JWF A;  2B3Z A;  1D1G A;  2FZI A;  4KLX A;  1U72 A;  4KYA A;  3SRU X;  1DR4 A;  3QLX A;  3FL8 A;  3NXT A;  1DR7 A;  1SEJ A;  3EEJ A;  1RX6 A;  1DG7 A;  4I13 A;  4X5I A;  3JSU A;  3NZ6 X;  1DYH A;  2G6V A;  4IXG X;  1CZ3 A;  1DYI A;  2FZJ A;  1DRA A;  2ANO A;  4KAK A;  5HF2 X;  1DRE A;  3TQ8 A;  2W3M A;  3SRQ X;  2P4G A;  3S7A A;  3FQ0 A;  3JW3 A;  4X5H A;  1HFP A;  1DG8 A;  1RC4 A;  2ITH A;  1DHF A;  4HA7 A;  1RX5 A;  2W9T A;  4EIZ A;  5JA3 A;  3SA1 A;  1DR6 A;  3K74 A;  4HOG A;  2BLC A;  3IX9 A;  2D0K A;  1DRB A;  1RX7 A;  3FQF A;  4GH8 A;  3F0Q X;  1DR3 A;  2D5N A;  3IA5 A;  1LUD A;  4KY8 A;  5ECX A;  4X5F A;  3I8A X;  1AOE A;  1S3U A;  5CC9 A;  3KJR A;  5JG0 X;  5ECC A;  3IRO A; 
#chains in the Genus database with same CATH topology
 3HJ3 A;  1S3Y A;  2BLB A;  3FYW X;  1CD2 A;  3EX8 A;  3F0U X;  3FS6 A;  1DHI A;  4H97 A;  3D84 X;  5HPB A;  4IXF X;  1PD8 A;  1DLS A;  3GHC A;  8DFR A;  3FRF X;  4XE6 X;  3FQZ A;  5DXV A;  3F91 A;  3SR5 X;  3TQ9 A;  3JWM A;  4RGC A;  5U26 A;  1JOM A;  3KY8 A;  1VDR A;  4QHV A;  4H96 A;  4PTH A;  3SAI A;  3LG4 A;  5DFR A;  3TD8 A;  4DFR A;  2CIG A;  3DL5 A;  3DAU A;  2AZN A;  3HBB A;  5HUI A;  1DLR A;  4ELB A;  3IRM A;  1ZDR A;  4KNE A;  3NZ9 X;  1KLK A;  4M7U A;  4Q6A A;  5HSU A;  3Q1H A;  5HT4 A;  4ELE A;  4KM2 A;  4FGG A;  3DG8 A;  3CSE A;  2W3B A;  1DRF A;  4X5G A;  2W3V A;  1RX2 A;  3NXY A;  4PDJ A;  3D80 A;  1RX4 A;  2HQP A;  3FRB X;  3FRA X;  1DRH A;  3FQC A;  4M7V A;  4XEC X;  3NTZ A;  3SRW X;  3EEL A;  3SH2 A;  2DHF A;  4Q0D A;  3JTW A;  4QJZ D;  2LF1 A;  4NX7 A;  4ELF A;  3F8Z A;  1RH3 A;  3INV A;  3QLW A;  3F0B X;  3EEM A;  1DYJ A;  5HI6 A;  1U71 A;  4M6L A;  5CCC A;  3NXO A;  2OBC A;  1RX1 A;  4KD7 A;  2C2S A;  4H98 A;  4CD2 A;  3M09 A;  2INQ A;  3K2H A;  4X5J A;  3CL9 A;  1DR2 A;  3NZC X;  3KFY A;  1OHJ A;  1VJ3 A;  4KY4 A;  4H95 A;  3F0X X;  4XT6 A;  4Q67 A;  4KL9 A;  4M6J A;  1RA8 A;  4DP3 A;  2OIP A;  2W3W A;  4PSS A;  4P66 A;  3FYV X;  1RX8 A;  3SRS X;  3DFR A;  4ELG A;  4FHB A;  1DIS A;  3EEK A;  4PST A;  4G8Z X;  1RX3 A;  1PDB A;  4KM0 A;  3ZPG A;  2BLA A;  2W3A A;  3NXR A;  4PSY A;  3S9U A;  3QLY A;  2H2Q A;  2CD2 A;  3UM5 A;  4M2X A;  2O7P A;  3FL9 A;  1MVS A;  6DFR A;  3SRR X;  5E8Q A;  3FQV A;  4QLF A;  2W9S A;  4TU5 X;  1DDS A;  1DF7 A;  3FY9 X;  3FY8 X;  2KGK A;  5U27 A;  1OHK A;  1DAJ A;  4DDR A;  5HVB A;  1IA3 A;  4G3M A;  5HQY A;  3JWC A;  1RA9 A;  1RA1 A;  4FGH A;  3ROA A;  3RG9 A;  3OAF A;  3QLS A;  3S3V A;  1DDR A;  3RO9 A;  1TDR A;  1DIU A;  4KJL A;  1DR5 A;  3QGT A;  1JUV A;  3QLR A;  4IXE D;  4KBN A;  3CD2 A;  1QZF A;  1RB3 A;  1M78 A;  3JW5 A;  2FZH A;  4I1N A;  7DFR A;  3FQO A;  3F0S X;  1DR1 A;  3KGY A;  1IA1 A;  2DRC A;  1JOL A;  5HT5 A;  4HA9 A;  3DRC A;  1U70 A;  3IA4 A;  4DPH A;  1LY4 A;  1BZF A;  2HXV A;  2ANQ A;  1BOZ A;  3JVX A;  1DHJ A;  5EAJ A;  3DL6 A;  4OR7 A;  4KEB A;  4PTJ A;  4XT7 A;  4QI9 A;  1RF7 A;  4KJK A;  3F8Y A;  3IRN A;  1RX9 A;  4LEK X;  2QK8 A;  3GHV A;  3SGY A;  3KJS A;  3JWK A;  4KFJ A;  4P3Q A;  4ECK A;  3ZPC A;  2W9H A;  1J3I A;  3UM6 A;  2W9G A;  2GD9 A;  4EJ1 A;  4LAH X;  1KMS A;  3L3R A;  1HFQ A;  3QL0 A;  3NZD A;  4P68 A;  1HFR A;  4G95 A;  1RE7 A;  2XW7 A;  3M08 A;  1J3J A;  3GI2 A;  4Q0E A;  3TQA A;  5HSR A;  4EIL A;  3DAT A;  1LY3 A;  3NZB X;  4XRB A;  3QG2 A;  1IA4 A;  3QL3 A;  3TQB A;  4M6K A;  3SQY X;  1MVT A;  3EIG A;  3I3R A;  1DYR A;  1RA2 A;  4ELH A;  3NU0 A;  1S3W A;  3NXV A;  2HM9 A;  3QLZ A;  3DGA A;  3R33 A;  4HOF A;  5HVE A;  1J3K A;  1RD7 A;  2JYB A;  4DPD A;  4XT5 A;  4KJJ A;  3N0H A;  4QLG A;  3F0V X;  3SA2 A;  3E0B A;  4LAG X;  3NXX A;  3QYO A;  1RA3 A;  3VCO A;  3FRE X;  4P3R A;  1PD9 A;  5HF0 X;  4LAE X;  3NRR A;  1AO8 A;  3OCH A;  3QFX A;  4XT4 A;  4QJC A;  1M79 A;  1RB2 A;  4EIG A;  3UM8 A;  3QYL A;  4XT8 A;  3GHW A;  1YHO A;  4OSG A;  3NZA X;  1DG5 A;  1KMV A;  3CLB A;  2C2T A;  3GYF A;  3K47 A;  4HOE A;  1RG7 A;  2BL9 A;  3FRD X;  1E26 A;  3K45 A;  4QLE A;  1AI9 A;  5HQZ A;  5FDA A;  4NX6 A;  1S3V A;  2ZZA A;  1M7A A;  1IA2 A;  2L28 A;  3JWF A;  2B3Z A;  1D1G A;  2FZI A;  4KLX A;  1U72 A;  4KYA A;  3SRU X;  1DR4 A;  3QLX A;  3FL8 A;  3NXT A;  1DR7 A;  1SEJ A;  3EEJ A;  1RX6 A;  1DG7 A;  4I13 A;  4X5I A;  3JSU A;  3NZ6 X;  1DYH A;  2G6V A;  4IXG X;  1CZ3 A;  1DYI A;  2FZJ A;  1DRA A;  2ANO A;  4KAK A;  5HF2 X;  1DRE A;  3TQ8 A;  2W3M A;  3SRQ X;  2P4G A;  3S7A A;  3FQ0 A;  3JW3 A;  4X5H A;  1HFP A;  1DG8 A;  1RC4 A;  2ITH A;  1DHF A;  4HA7 A;  1RX5 A;  2W9T A;  4EIZ A;  5JA3 A;  3SA1 A;  1DR6 A;  3K74 A;  4HOG A;  2BLC A;  3IX9 A;  2D0K A;  1DRB A;  1RX7 A;  3FQF A;  4GH8 A;  3F0Q X;  1DR3 A;  2D5N A;  3IA5 A;  1LUD A;  4KY8 A;  5ECX A;  4X5F A;  3I8A X;  1AOE A;  1S3U A;  5CC9 A;  3KJR A;  5JG0 X;  5ECC A;  3IRO A; 
#chains in the Genus database with same CATH homology
 3HJ3 A;  1S3Y A;  2BLB A;  3FYW X;  1CD2 A;  3EX8 A;  3F0U X;  3FS6 A;  1DHI A;  4H97 A;  3D84 X;  5HPB A;  4IXF X;  1PD8 A;  1DLS A;  3GHC A;  8DFR A;  3FRF X;  4XE6 X;  3FQZ A;  5DXV A;  3F91 A;  3SR5 X;  3TQ9 A;  3JWM A;  4RGC A;  5U26 A;  1JOM A;  3KY8 A;  1VDR A;  4QHV A;  4H96 A;  4PTH A;  3SAI A;  3LG4 A;  5DFR A;  3TD8 A;  4DFR A;  2CIG A;  3DL5 A;  3DAU A;  2AZN A;  3HBB A;  5HUI A;  1DLR A;  4ELB A;  3IRM A;  1ZDR A;  4KNE A;  3NZ9 X;  1KLK A;  4M7U A;  4Q6A A;  5HSU A;  3Q1H A;  5HT4 A;  4ELE A;  4KM2 A;  4FGG A;  3DG8 A;  3CSE A;  2W3B A;  1DRF A;  4X5G A;  2W3V A;  1RX2 A;  3NXY A;  4PDJ A;  3D80 A;  1RX4 A;  2HQP A;  3FRB X;  3FRA X;  1DRH A;  3FQC A;  4M7V A;  4XEC X;  3NTZ A;  3SRW X;  3EEL A;  3SH2 A;  2DHF A;  4Q0D A;  3JTW A;  4QJZ D;  2LF1 A;  4NX7 A;  4ELF A;  3F8Z A;  1RH3 A;  3INV A;  3QLW A;  3F0B X;  3EEM A;  1DYJ A;  5HI6 A;  1U71 A;  4M6L A;  5CCC A;  3NXO A;  2OBC A;  1RX1 A;  4KD7 A;  2C2S A;  4H98 A;  4CD2 A;  3M09 A;  2INQ A;  3K2H A;  4X5J A;  3CL9 A;  1DR2 A;  3NZC X;  3KFY A;  1OHJ A;  1VJ3 A;  4KY4 A;  4H95 A;  3F0X X;  4XT6 A;  4Q67 A;  4KL9 A;  4M6J A;  1RA8 A;  4DP3 A;  2OIP A;  2W3W A;  4PSS A;  4P66 A;  3FYV X;  1RX8 A;  3SRS X;  3DFR A;  4ELG A;  4FHB A;  1DIS A;  3EEK A;  4PST A;  4G8Z X;  1RX3 A;  1PDB A;  4KM0 A;  3ZPG A;  2BLA A;  2W3A A;  3NXR A;  4PSY A;  3S9U A;  3QLY A;  2H2Q A;  2CD2 A;  3UM5 A;  4M2X A;  2O7P A;  3FL9 A;  1MVS A;  6DFR A;  3SRR X;  5E8Q A;  3FQV A;  4QLF A;  2W9S A;  4TU5 X;  1DDS A;  1DF7 A;  3FY9 X;  3FY8 X;  2KGK A;  5U27 A;  1OHK A;  1DAJ A;  4DDR A;  5HVB A;  1IA3 A;  4G3M A;  5HQY A;  3JWC A;  1RA9 A;  1RA1 A;  4FGH A;  3ROA A;  3RG9 A;  3OAF A;  3QLS A;  3S3V A;  1DDR A;  3RO9 A;  1TDR A;  1DIU A;  4KJL A;  1DR5 A;  3QGT A;  1JUV A;  3QLR A;  4IXE D;  4KBN A;  3CD2 A;  1QZF A;  1RB3 A;  1M78 A;  3JW5 A;  2FZH A;  4I1N A;  7DFR A;  3FQO A;  3F0S X;  1DR1 A;  3KGY A;  1IA1 A;  2DRC A;  1JOL A;  5HT5 A;  4HA9 A;  3DRC A;  1U70 A;  3IA4 A;  4DPH A;  1LY4 A;  1BZF A;  2HXV A;  2ANQ A;  1BOZ A;  3JVX A;  1DHJ A;  5EAJ A;  3DL6 A;  4OR7 A;  4KEB A;  4PTJ A;  4XT7 A;  4QI9 A;  1RF7 A;  4KJK A;  3F8Y A;  3IRN A;  1RX9 A;  4LEK X;  2QK8 A;  3GHV A;  3SGY A;  3KJS A;  3JWK A;  4KFJ A;  4P3Q A;  4ECK A;  3ZPC A;  2W9H A;  1J3I A;  3UM6 A;  2W9G A;  2GD9 A;  4EJ1 A;  4LAH X;  1KMS A;  3L3R A;  1HFQ A;  3QL0 A;  3NZD A;  4P68 A;  1HFR A;  4G95 A;  1RE7 A;  2XW7 A;  3M08 A;  1J3J A;  3GI2 A;  4Q0E A;  3TQA A;  5HSR A;  4EIL A;  3DAT A;  1LY3 A;  3NZB X;  4XRB A;  3QG2 A;  1IA4 A;  3QL3 A;  3TQB A;  4M6K A;  3SQY X;  1MVT A;  3EIG A;  3I3R A;  1DYR A;  1RA2 A;  4ELH A;  3NU0 A;  1S3W A;  3NXV A;  2HM9 A;  3QLZ A;  3DGA A;  3R33 A;  4HOF A;  5HVE A;  1J3K A;  1RD7 A;  2JYB A;  4DPD A;  4XT5 A;  4KJJ A;  3N0H A;  4QLG A;  3F0V X;  3SA2 A;  3E0B A;  4LAG X;  3NXX A;  3QYO A;  1RA3 A;  3VCO A;  3FRE X;  4P3R A;  1PD9 A;  5HF0 X;  4LAE X;  3NRR A;  1AO8 A;  3OCH A;  3QFX A;  4XT4 A;  4QJC A;  1M79 A;  1RB2 A;  4EIG A;  3UM8 A;  3QYL A;  4XT8 A;  3GHW A;  1YHO A;  4OSG A;  3NZA X;  1DG5 A;  1KMV A;  3CLB A;  2C2T A;  3GYF A;  3K47 A;  4HOE A;  1RG7 A;  2BL9 A;  3FRD X;  1E26 A;  3K45 A;  4QLE A;  1AI9 A;  5HQZ A;  5FDA A;  4NX6 A;  1S3V A;  2ZZA A;  1M7A A;  1IA2 A;  2L28 A;  3JWF A;  2B3Z A;  1D1G A;  2FZI A;  4KLX A;  1U72 A;  4KYA A;  3SRU X;  1DR4 A;  3QLX A;  3FL8 A;  3NXT A;  1DR7 A;  1SEJ A;  3EEJ A;  1RX6 A;  1DG7 A;  4I13 A;  4X5I A;  3JSU A;  3NZ6 X;  1DYH A;  2G6V A;  4IXG X;  1CZ3 A;  1DYI A;  2FZJ A;  1DRA A;  2ANO A;  4KAK A;  5HF2 X;  1DRE A;  3TQ8 A;  2W3M A;  3SRQ X;  2P4G A;  3S7A A;  3FQ0 A;  3JW3 A;  4X5H A;  1HFP A;  1DG8 A;  1RC4 A;  2ITH A;  1DHF A;  4HA7 A;  1RX5 A;  2W9T A;  4EIZ A;  5JA3 A;  3SA1 A;  1DR6 A;  3K74 A;  4HOG A;  2BLC A;  3IX9 A;  2D0K A;  1DRB A;  1RX7 A;  3FQF A;  4GH8 A;  3F0Q X;  1DR3 A;  2D5N A;  3IA5 A;  1LUD A;  4KY8 A;  5ECX A;  4X5F A;  3I8A X;  1AOE A;  1S3U A;  5CC9 A;  3KJR A;  5JG0 X;  5ECC A;  3IRO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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