4DDRA

Human dihydrofolate reductase complexed with nadph and p218
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
186
structure length
186
Chain Sequence
VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Homo sapiens
molecule keywords Dihydrofolate reductase
total genus 56
structure length 186
sequence length 186
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2012-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4ddrA00
3Q1HA 5DXVA 3QLXA 2OBCA 3TD8A 4PTJA 1M78A 1JOLA 1DREA 1RX6A 4HOEA 4IXED 2W3AA 1CZ3A 4PDJA 3JW3A 2FZHA 4EIZA 1PD8A 3JW5A 3KFYA 3SRQX 4H96A 5HSRA 2P4GA 5HT5A 3UM6A 1PD9A 4QLGA 2HM9A 1VDRA 4H97A 2W9GA 3RG9A 2C2SA 7DFRA 1RX9A 5CCCA 3NZAX 3CSEA 3NRRA 3NZCX 1VJ3A 4KY8A 3QYLA 4TU5X 1BZFA 3SRWX 3QLRA 4KEBA 3NXTA 4PSYA 1IA1A 1DHJA 3QLSA 3QLZA 3SQYX 1RX5A 3NXOA 5HVBA 4HOGA 4ELFA 4FGHA 2AZNA 3FRAX 4KNEA 3DL6A 3EIGA 1DG5A 3FRBX 1J3KA 1J3IA 2HXVA 4Q0EA 4M7UA 3S9UA 3F0VX 5HQYA 4OSGA 1DISA 3FYWX 2CD2A 4ELEA 3EELA 4DDRA 1RX3A 4PSTA 2W9HA 3FQCA 1DLSA 1RX2A 1RC4A 4I1NA 4M6LA 3SRRX 4KAKA 2ZZAA 3NZ6X 1KMVA 2C2TA 5DFRA 1IA3A 2D0KA 4IXGX 4M2XA 4KFJA 1DYIA 1TDRA 3NXVA 4KD7A 3FQ0A 1DR2A 3DL5A 5JA3A 2FZIA 1DRAA 4QJCA 1DIUA 1RD7A 1RA1A 1RA3A 4XT5A 2CIGA 2W3VA 4XRBA 3HBBA 1ZDRA 3F0SX 2O7PA 3FYVX 1IA2A 3INVA 3TQ8A 4X5GA 4IXFX 1OHJA 2ANQA 4KM2A 1DYHA 6DFRA 4P66A 3SRSX 3N0HA 4QLFA 2W9SA 3NU0A 2DRCA 4FHBA 3GYFA 1DRFA 4EIGA 2W3WA 4ELBA 1YHOA 1JOMA 2W9TA 5HQZA 3I3RA 3FRFX 1DR4A 5ECCA 3UM8A 1RX7A 1J3JA 3NXXA 3IROA 3GHCA 3R33A 4QJZD 3FRDX 2BL9A 3DATA 3GI2A 1RB3A 4ELGA 1S3VA 3QYOA 3FQVA 1RB2A 4KBNA 4OR7A 1BOZA 1DRHA 4QI9A 3S3VA 1DDSA 3F91A 1U72A 4M7VA 4XT8A 1SEJA 3M08A 1RA2A 1HFRA 2INQA 2BLBA 3QFXA 3S7AA 4M6JA 1DR7A 4G3MA 5EAJA 2B3ZA 3DRCA 1JUVA 3NZDA 5CC9A 3CL9A 3QL0A 3DFRA 3JWKA 4HA7A 1AI9A 3TQAA 1LY3A 2H2QA 3ROAA 1DR6A 1KMSA 3KY8A 3SAIA 5U26A 3GHWA 3QLYA 1RF7A 3JSUA 5HI6A 1DR5A 2G6VA 5HSUA 3EEKA 3TQBA 2ITHA 3SH2A 4DPDA 5HF0X 4KY4A 2DHFA 1DAJA 4Q6AA 1DHIA 1DRBA 2XW7A 1PDBA 3QL3A 1AOEA 4PSSA 1DYJA 3FL9A 3IX9A 4QLEA 4KM0A 4P3RA 1RG7A 1U70A 1DDRA 3I8AX 5HPBA 2FZJA 2ANOA 1M79A 1DG7A 4M6KA 3FY9X 4H98A 3F0XX 4KJJA 4X5JA 4NX6A 4DP3A 3NZBX 1RX8A 3FQFA 3IA4A 1CD2A 5FDAA 3NXYA 3SRUX 4HOFA 5ECXA 3EX8A 1U71A 4KYAA 3SA2A 3F8YA 3IA5A 3F0BX 1MVSA 3CD2A 4KLXA 3UM5A 3JVXA 4Q67A 3NZ9X 3GHVA 4QHVA 3QLWA 3HJ3A 2JYBA 4HA9A 3SR5X 3QG2A 3TQ9A 3ZPCA 4P68A 3F8ZA 1HFPA 3F0QX 1S3WA 3FREX 5JG0X 3D80A 4I13A 2HQPA 3JWMA 4LEKX 1AO8A 3JWFA 1DG8A 4G95A 5E8QA 4XT6A 4ECKA 4XE6X 1RA9A 3DG8A 1IA4A 2KGKA 4ELHA 3FQZA 3K47A 1LY4A 3OCHA 1OHKA 1LUDA 4PTHA 2QK8A 4GH8A 1DR1A 3FS6A 3NTZA 4H95A 3D84X 2BLAA 4KJLA 3F0UX 1DYRA 4EJ1A 3SA1A 4KJKA 2L28A 4X5HA 5HF2X 3JTWA 4LAHX 4XT7A 5HT4A 5HUIA 3OAFA 2GD9A 4RGCA 2LF1A 4P3QA 1S3UA 4XT4A 3IRNA 3FY8X 3M09A 3SGYA 3KJSA 1MVTA 2OIPA 1RE7A 3LG4A 3CLBA 5U27A 4XECX 4CD2A 3KJRA 1RH3A 4X5FA 3K74A 1DR3A 5HVEA 4LAEX 1E26A 1D1GA 4EILA 3E0BA 4FGGA 4DPHA 3JWCA 4X5IA 1M7AA 1QZFA 3FL8A 1RX4A 3VCOA 1KLKA 4LAGX 4G8ZX 2D5NA 3EEJA 2BLCA 1DF7A 1RX1A 4NX7A 3K45A 8DFRA 3EEMA 3KGYA 3DGAA 3ZPGA 3FQOA 1S3YA 3IRMA 3RO9A 2W3BA 1RA8A 3NXRA 2W3MA 3DAUA 4Q0DA 4DFRA 1HFQA 3K2HA 1DHFA 3QGTA 3L3RA 1DLRA 4KL9A
chains in the Genus database with same CATH superfamily
3Q1HA 5DXVA 3QLXA 2OBCA 3TD8A 4PTJA 1M78A 1JOLA 1DREA 1RX6A 4HOEA 4IXED 2W3AA 1CZ3A 4PDJA 3JW3A 2FZHA 4EIZA 1PD8A 3JW5A 3KFYA 3SRQX 4H96A 5HSRA 2P4GA 5HT5A 3UM6A 1PD9A 4QLGA 2HM9A 1VDRA 4H97A 2W9GA 3RG9A 2C2SA 7DFRA 1RX9A 5CCCA 3NZAX 3CSEA 3NRRA 3NZCX 1VJ3A 4KY8A 3QYLA 4TU5X 1BZFA 3SRWX 3QLRA 4KEBA 3NXTA 4PSYA 1IA1A 1DHJA 3QLSA 3QLZA 3SQYX 1RX5A 3NXOA 5HVBA 4HOGA 4ELFA 4FGHA 2AZNA 3FRAX 4KNEA 3DL6A 3EIGA 1DG5A 3FRBX 1J3KA 1J3IA 2HXVA 4Q0EA 4M7UA 3S9UA 3F0VX 5HQYA 4OSGA 1DISA 3FYWX 2CD2A 4ELEA 3EELA 4DDRA 1RX3A 4PSTA 2W9HA 3FQCA 1DLSA 1RX2A 1RC4A 4I1NA 4M6LA 3SRRX 4KAKA 2ZZAA 3NZ6X 1KMVA 2C2TA 5DFRA 1IA3A 2D0KA 4IXGX 4M2XA 4KFJA 1DYIA 1TDRA 3NXVA 4KD7A 3FQ0A 1DR2A 3DL5A 5JA3A 2FZIA 1DRAA 4QJCA 1DIUA 1RD7A 1RA1A 1RA3A 4XT5A 2CIGA 2W3VA 4XRBA 3HBBA 1ZDRA 3F0SX 2O7PA 3FYVX 1IA2A 3INVA 3TQ8A 4X5GA 4IXFX 1OHJA 2ANQA 4KM2A 1DYHA 6DFRA 4P66A 3SRSX 3N0HA 4QLFA 2W9SA 3NU0A 2DRCA 4FHBA 3GYFA 1DRFA 4EIGA 2W3WA 4ELBA 1YHOA 1JOMA 2W9TA 5HQZA 3I3RA 3FRFX 1DR4A 5ECCA 3UM8A 1RX7A 1J3JA 3NXXA 3IROA 3GHCA 3R33A 4QJZD 3FRDX 2BL9A 3DATA 3GI2A 1RB3A 4ELGA 1S3VA 3QYOA 3FQVA 1RB2A 4KBNA 4OR7A 1BOZA 1DRHA 4QI9A 3S3VA 1DDSA 3F91A 1U72A 4M7VA 4XT8A 1SEJA 3M08A 1RA2A 1HFRA 2INQA 2BLBA 3QFXA 3S7AA 4M6JA 1DR7A 4G3MA 5EAJA 2B3ZA 3DRCA 1JUVA 3NZDA 5CC9A 3CL9A 3QL0A 3DFRA 3JWKA 4HA7A 1AI9A 3TQAA 1LY3A 2H2QA 3ROAA 1DR6A 1KMSA 3KY8A 3SAIA 5U26A 3GHWA 3QLYA 1RF7A 3JSUA 5HI6A 1DR5A 2G6VA 5HSUA 3EEKA 3TQBA 2ITHA 3SH2A 4DPDA 5HF0X 4KY4A 2DHFA 1DAJA 4Q6AA 1DHIA 1DRBA 2XW7A 1PDBA 3QL3A 1AOEA 4PSSA 1DYJA 3FL9A 3IX9A 4QLEA 4KM0A 4P3RA 1RG7A 1U70A 1DDRA 3I8AX 5HPBA 2FZJA 2ANOA 1M79A 1DG7A 4M6KA 3FY9X 4H98A 3F0XX 4KJJA 4X5JA 4NX6A 4DP3A 3NZBX 1RX8A 3FQFA 3IA4A 1CD2A 5FDAA 3NXYA 3SRUX 4HOFA 5ECXA 3EX8A 1U71A 4KYAA 3SA2A 3F8YA 3IA5A 3F0BX 1MVSA 3CD2A 4KLXA 3UM5A 3JVXA 4Q67A 3NZ9X 3GHVA 4QHVA 3QLWA 3HJ3A 2JYBA 4HA9A 3SR5X 3QG2A 3TQ9A 3ZPCA 4P68A 3F8ZA 1HFPA 3F0QX 1S3WA 3FREX 5JG0X 3D80A 4I13A 2HQPA 3JWMA 4LEKX 1AO8A 3JWFA 1DG8A 4G95A 5E8QA 4XT6A 4ECKA 4XE6X 1RA9A 3DG8A 1IA4A 2KGKA 4ELHA 3FQZA 3K47A 1LY4A 3OCHA 1OHKA 1LUDA 4PTHA 2QK8A 4GH8A 1DR1A 3FS6A 3NTZA 4H95A 3D84X 2BLAA 4KJLA 3F0UX 1DYRA 4EJ1A 3SA1A 4KJKA 2L28A 4X5HA 5HF2X 3JTWA 4LAHX 4XT7A 5HT4A 5HUIA 3OAFA 2GD9A 4RGCA 2LF1A 4P3QA 1S3UA 4XT4A 3IRNA 3FY8X 3M09A 3SGYA 3KJSA 1MVTA 2OIPA 1RE7A 3LG4A 3CLBA 5U27A 4XECX 4CD2A 3KJRA 1RH3A 4X5FA 3K74A 1DR3A 5HVEA 4LAEX 1E26A 1D1GA 4EILA 3E0BA 4FGGA 4DPHA 3JWCA 4X5IA 1M7AA 1QZFA 3FL8A 1RX4A 3VCOA 1KLKA 4LAGX 4G8ZX 2D5NA 3EEJA 2BLCA 1DF7A 1RX1A 4NX7A 3K45A 8DFRA 3EEMA 3KGYA 3DGAA 3ZPGA 3FQOA 1S3YA 3IRMA 3RO9A 2W3BA 1RA8A 3NXRA 2W3MA 3DAUA 4Q0DA 4DFRA 1HFQA 3K2HA 1DHFA 3QGTA 3L3RA 1DLRA 4KL9A
chains in the Genus database with same CATH topology
3Q1HA 5DXVA 3QLXA 2OBCA 3TD8A 4PTJA 1M78A 1JOLA 1DREA 1RX6A 4HOEA 4IXED 2W3AA 1CZ3A 4PDJA 3JW3A 2FZHA 4EIZA 1PD8A 3JW5A 3KFYA 3SRQX 4H96A 5HSRA 2P4GA 5HT5A 3UM6A 1PD9A 4QLGA 2HM9A 1VDRA 4H97A 2W9GA 3RG9A 2C2SA 7DFRA 1RX9A 5CCCA 3NZAX 3CSEA 3NRRA 3NZCX 1VJ3A 4KY8A 3QYLA 4TU5X 1BZFA 3SRWX 3QLRA 4KEBA 3NXTA 4PSYA 1IA1A 1DHJA 3QLSA 3QLZA 3SQYX 1RX5A 3NXOA 5HVBA 4HOGA 4ELFA 4FGHA 2AZNA 3FRAX 4KNEA 3DL6A 3EIGA 1DG5A 3FRBX 1J3KA 1J3IA 2HXVA 4Q0EA 4M7UA 3S9UA 3F0VX 5HQYA 4OSGA 1DISA 3FYWX 2CD2A 4ELEA 3EELA 4DDRA 1RX3A 4PSTA 2W9HA 3FQCA 1DLSA 1RX2A 1RC4A 4I1NA 4M6LA 3SRRX 4KAKA 2ZZAA 3NZ6X 1KMVA 2C2TA 5DFRA 1IA3A 2D0KA 4IXGX 4M2XA 4KFJA 1DYIA 1TDRA 3NXVA 4KD7A 3FQ0A 1DR2A 3DL5A 5JA3A 2FZIA 1DRAA 4QJCA 1DIUA 1RD7A 1RA1A 1RA3A 4XT5A 2CIGA 2W3VA 4XRBA 3HBBA 1ZDRA 3F0SX 2O7PA 3FYVX 1IA2A 3INVA 3TQ8A 4X5GA 4IXFX 1OHJA 2ANQA 4KM2A 1DYHA 6DFRA 4P66A 3SRSX 3N0HA 4QLFA 2W9SA 3NU0A 2DRCA 4FHBA 3GYFA 1DRFA 4EIGA 2W3WA 4ELBA 1YHOA 1JOMA 2W9TA 5HQZA 3I3RA 3FRFX 1DR4A 5ECCA 3UM8A 1RX7A 1J3JA 3NXXA 3IROA 3GHCA 3R33A 4QJZD 3FRDX 2BL9A 3DATA 3GI2A 1RB3A 4ELGA 1S3VA 3QYOA 3FQVA 1RB2A 4KBNA 4OR7A 1BOZA 1DRHA 4QI9A 3S3VA 1DDSA 3F91A 1U72A 4M7VA 4XT8A 1SEJA 3M08A 1RA2A 1HFRA 2INQA 2BLBA 3QFXA 3S7AA 4M6JA 1DR7A 4G3MA 5EAJA 2B3ZA 3DRCA 1JUVA 3NZDA 5CC9A 3CL9A 3QL0A 3DFRA 3JWKA 4HA7A 1AI9A 3TQAA 1LY3A 2H2QA 3ROAA 1DR6A 1KMSA 3KY8A 3SAIA 5U26A 3GHWA 3QLYA 1RF7A 3JSUA 5HI6A 1DR5A 2G6VA 5HSUA 3EEKA 3TQBA 2ITHA 3SH2A 4DPDA 5HF0X 4KY4A 2DHFA 1DAJA 4Q6AA 1DHIA 1DRBA 2XW7A 1PDBA 3QL3A 1AOEA 4PSSA 1DYJA 3FL9A 3IX9A 4QLEA 4KM0A 4P3RA 1RG7A 1U70A 1DDRA 3I8AX 5HPBA 2FZJA 2ANOA 1M79A 1DG7A 4M6KA 3FY9X 4H98A 3F0XX 4KJJA 4X5JA 4NX6A 4DP3A 3NZBX 1RX8A 3FQFA 3IA4A 1CD2A 5FDAA 3NXYA 3SRUX 4HOFA 5ECXA 3EX8A 1U71A 4KYAA 3SA2A 3F8YA 3IA5A 3F0BX 1MVSA 3CD2A 4KLXA 3UM5A 3JVXA 4Q67A 3NZ9X 3GHVA 4QHVA 3QLWA 3HJ3A 2JYBA 4HA9A 3SR5X 3QG2A 3TQ9A 3ZPCA 4P68A 3F8ZA 1HFPA 3F0QX 1S3WA 3FREX 5JG0X 3D80A 4I13A 2HQPA 3JWMA 4LEKX 1AO8A 3JWFA 1DG8A 4G95A 5E8QA 4XT6A 4ECKA 4XE6X 1RA9A 3DG8A 1IA4A 2KGKA 4ELHA 3FQZA 3K47A 1LY4A 3OCHA 1OHKA 1LUDA 4PTHA 2QK8A 4GH8A 1DR1A 3FS6A 3NTZA 4H95A 3D84X 2BLAA 4KJLA 3F0UX 1DYRA 4EJ1A 3SA1A 4KJKA 2L28A 4X5HA 5HF2X 3JTWA 4LAHX 4XT7A 5HT4A 5HUIA 3OAFA 2GD9A 4RGCA 2LF1A 4P3QA 1S3UA 4XT4A 3IRNA 3FY8X 3M09A 3SGYA 3KJSA 1MVTA 2OIPA 1RE7A 3LG4A 3CLBA 5U27A 4XECX 4CD2A 3KJRA 1RH3A 4X5FA 3K74A 1DR3A 5HVEA 4LAEX 1E26A 1D1GA 4EILA 3E0BA 4FGGA 4DPHA 3JWCA 4X5IA 1M7AA 1QZFA 3FL8A 1RX4A 3VCOA 1KLKA 4LAGX 4G8ZX 2D5NA 3EEJA 2BLCA 1DF7A 1RX1A 4NX7A 3K45A 8DFRA 3EEMA 3KGYA 3DGAA 3ZPGA 3FQOA 1S3YA 3IRMA 3RO9A 2W3BA 1RA8A 3NXRA 2W3MA 3DAUA 4Q0DA 4DFRA 1HFQA 3K2HA 1DHFA 3QGTA 3L3RA 1DLRA 4KL9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q1H A;  5DXV A;  3QLX A;  2OBC A;  3TD8 A;  4PTJ A;  1M78 A;  1JOL A;  1DRE A;  1RX6 A;  4HOE A;  4IXE D;  2W3A A;  1CZ3 A;  4PDJ A;  3JW3 A;  2FZH A;  4EIZ A;  1PD8 A;  3JW5 A;  3KFY A;  3SRQ X;  4H96 A;  5HSR A;  2P4G A;  5HT5 A;  3UM6 A;  1PD9 A;  4QLG A;  2HM9 A;  1VDR A;  4H97 A;  2W9G A;  3RG9 A;  2C2S A;  7DFR A;  1RX9 A;  5CCC A;  3NZA X;  3CSE A;  3NRR A;  3NZC X;  1VJ3 A;  4KY8 A;  3QYL A;  4TU5 X;  1BZF A;  3SRW X;  3QLR A;  4KEB A;  3NXT A;  4PSY A;  1IA1 A;  1DHJ A;  3QLS A;  3QLZ A;  3SQY X;  1RX5 A;  3NXO A;  5HVB A;  4HOG A;  4ELF A;  4FGH A;  2AZN A;  3FRA X;  4KNE A;  3DL6 A;  3EIG A;  1DG5 A;  3FRB X;  1J3K A;  1J3I A;  2HXV A;  4Q0E A;  4M7U A;  3S9U A;  3F0V X;  5HQY A;  4OSG A;  1DIS A;  3FYW X;  2CD2 A;  4ELE A;  3EEL A;  4DDR A;  1RX3 A;  4PST A;  2W9H A;  3FQC A;  1DLS A;  1RX2 A;  1RC4 A;  4I1N A;  4M6L A;  3SRR X;  4KAK A;  2ZZA A;  3NZ6 X;  1KMV A;  2C2T A;  5DFR A;  1IA3 A;  2D0K A;  4IXG X;  4M2X A;  4KFJ A;  1DYI A;  1TDR A;  3NXV A;  4KD7 A;  3FQ0 A;  1DR2 A;  3DL5 A;  5JA3 A;  2FZI A;  1DRA A;  4QJC A;  1DIU A;  1RD7 A;  1RA1 A;  1RA3 A;  4XT5 A;  2CIG A;  2W3V A;  4XRB A;  3HBB A;  1ZDR A;  3F0S X;  2O7P A;  3FYV X;  1IA2 A;  3INV A;  3TQ8 A;  4X5G A;  4IXF X;  1OHJ A;  2ANQ A;  4KM2 A;  1DYH A;  6DFR A;  4P66 A;  3SRS X;  3N0H A;  4QLF A;  2W9S A;  3NU0 A;  2DRC A;  4FHB A;  3GYF A;  1DRF A;  4EIG A;  2W3W A;  4ELB A;  1YHO A;  1JOM A;  2W9T A;  5HQZ A;  3I3R A;  3FRF X;  1DR4 A;  5ECC A;  3UM8 A;  1RX7 A;  1J3J A;  3NXX A;  3IRO A;  3GHC A;  3R33 A;  4QJZ D;  3FRD X;  2BL9 A;  3DAT A;  3GI2 A;  1RB3 A;  4ELG A;  1S3V A;  3QYO A;  3FQV A;  1RB2 A;  4KBN A;  4OR7 A;  1BOZ A;  1DRH A;  4QI9 A;  3S3V A;  1DDS A;  3F91 A;  1U72 A;  4M7V A;  4XT8 A;  1SEJ A;  3M08 A;  1RA2 A;  1HFR A;  2INQ A;  2BLB A;  3QFX A;  3S7A A;  4M6J A;  1DR7 A;  4G3M A;  5EAJ A;  2B3Z A;  3DRC A;  1JUV A;  3NZD A;  5CC9 A;  3CL9 A;  3QL0 A;  3DFR A;  3JWK A;  4HA7 A;  1AI9 A;  3TQA A;  1LY3 A;  2H2Q A;  3ROA A;  1DR6 A;  1KMS A;  3KY8 A;  3SAI A;  5U26 A;  3GHW A;  3QLY A;  1RF7 A;  3JSU A;  5HI6 A;  1DR5 A;  2G6V A;  5HSU A;  3EEK A;  3TQB A;  2ITH A;  3SH2 A;  4DPD A;  5HF0 X;  4KY4 A;  2DHF A;  1DAJ A;  4Q6A A;  1DHI A;  1DRB A;  2XW7 A;  1PDB A;  3QL3 A;  1AOE A;  4PSS A;  1DYJ A;  3FL9 A;  3IX9 A;  4QLE A;  4KM0 A;  4P3R A;  1RG7 A;  1U70 A;  1DDR A;  3I8A X;  5HPB A;  2FZJ A;  2ANO A;  1M79 A;  1DG7 A;  4M6K A;  3FY9 X;  4H98 A;  3F0X X;  4KJJ A;  4X5J A;  4NX6 A;  4DP3 A;  3NZB X;  1RX8 A;  3FQF A;  3IA4 A;  1CD2 A;  5FDA A;  3NXY A;  3SRU X;  4HOF A;  5ECX A;  3EX8 A;  1U71 A;  4KYA A;  3SA2 A;  3F8Y A;  3IA5 A;  3F0B X;  1MVS A;  3CD2 A;  4KLX A;  3UM5 A;  3JVX A;  4Q67 A;  3NZ9 X;  3GHV A;  4QHV A;  3QLW A;  3HJ3 A;  2JYB A;  4HA9 A;  3SR5 X;  3QG2 A;  3TQ9 A;  3ZPC A;  4P68 A;  3F8Z A;  1HFP A;  3F0Q X;  1S3W A;  3FRE X;  5JG0 X;  3D80 A;  4I13 A;  2HQP A;  3JWM A;  4LEK X;  1AO8 A;  3JWF A;  1DG8 A;  4G95 A;  5E8Q A;  4XT6 A;  4ECK A;  4XE6 X;  1RA9 A;  3DG8 A;  1IA4 A;  2KGK A;  4ELH A;  3FQZ A;  3K47 A;  1LY4 A;  3OCH A;  1OHK A;  1LUD A;  4PTH A;  2QK8 A;  4GH8 A;  1DR1 A;  3FS6 A;  3NTZ A;  4H95 A;  3D84 X;  2BLA A;  4KJL A;  3F0U X;  1DYR A;  4EJ1 A;  3SA1 A;  4KJK A;  2L28 A;  4X5H A;  5HF2 X;  3JTW A;  4LAH X;  4XT7 A;  5HT4 A;  5HUI A;  3OAF A;  2GD9 A;  4RGC A;  2LF1 A;  4P3Q A;  1S3U A;  4XT4 A;  3IRN A;  3FY8 X;  3M09 A;  3SGY A;  3KJS A;  1MVT A;  2OIP A;  1RE7 A;  3LG4 A;  3CLB A;  5U27 A;  4XEC X;  4CD2 A;  3KJR A;  1RH3 A;  4X5F A;  3K74 A;  1DR3 A;  5HVE A;  4LAE X;  1E26 A;  1D1G A;  4EIL A;  3E0B A;  4FGG A;  4DPH A;  3JWC A;  4X5I A;  1M7A A;  1QZF A;  3FL8 A;  1RX4 A;  3VCO A;  1KLK A;  4LAG X;  4G8Z X;  2D5N A;  3EEJ A;  2BLC A;  1DF7 A;  1RX1 A;  4NX7 A;  3K45 A;  8DFR A;  3EEM A;  3KGY A;  3DGA A;  3ZPG A;  3FQO A;  1S3Y A;  3IRM A;  3RO9 A;  2W3B A;  1RA8 A;  3NXR A;  2W3M A;  3DAU A;  4Q0D A;  4DFR A;  1HFQ A;  3K2H A;  1DHF A;  3QGT A;  3L3R A;  1DLR A;  4KL9 A; 
#chains in the Genus database with same CATH topology
 3Q1H A;  5DXV A;  3QLX A;  2OBC A;  3TD8 A;  4PTJ A;  1M78 A;  1JOL A;  1DRE A;  1RX6 A;  4HOE A;  4IXE D;  2W3A A;  1CZ3 A;  4PDJ A;  3JW3 A;  2FZH A;  4EIZ A;  1PD8 A;  3JW5 A;  3KFY A;  3SRQ X;  4H96 A;  5HSR A;  2P4G A;  5HT5 A;  3UM6 A;  1PD9 A;  4QLG A;  2HM9 A;  1VDR A;  4H97 A;  2W9G A;  3RG9 A;  2C2S A;  7DFR A;  1RX9 A;  5CCC A;  3NZA X;  3CSE A;  3NRR A;  3NZC X;  1VJ3 A;  4KY8 A;  3QYL A;  4TU5 X;  1BZF A;  3SRW X;  3QLR A;  4KEB A;  3NXT A;  4PSY A;  1IA1 A;  1DHJ A;  3QLS A;  3QLZ A;  3SQY X;  1RX5 A;  3NXO A;  5HVB A;  4HOG A;  4ELF A;  4FGH A;  2AZN A;  3FRA X;  4KNE A;  3DL6 A;  3EIG A;  1DG5 A;  3FRB X;  1J3K A;  1J3I A;  2HXV A;  4Q0E A;  4M7U A;  3S9U A;  3F0V X;  5HQY A;  4OSG A;  1DIS A;  3FYW X;  2CD2 A;  4ELE A;  3EEL A;  4DDR A;  1RX3 A;  4PST A;  2W9H A;  3FQC A;  1DLS A;  1RX2 A;  1RC4 A;  4I1N A;  4M6L A;  3SRR X;  4KAK A;  2ZZA A;  3NZ6 X;  1KMV A;  2C2T A;  5DFR A;  1IA3 A;  2D0K A;  4IXG X;  4M2X A;  4KFJ A;  1DYI A;  1TDR A;  3NXV A;  4KD7 A;  3FQ0 A;  1DR2 A;  3DL5 A;  5JA3 A;  2FZI A;  1DRA A;  4QJC A;  1DIU A;  1RD7 A;  1RA1 A;  1RA3 A;  4XT5 A;  2CIG A;  2W3V A;  4XRB A;  3HBB A;  1ZDR A;  3F0S X;  2O7P A;  3FYV X;  1IA2 A;  3INV A;  3TQ8 A;  4X5G A;  4IXF X;  1OHJ A;  2ANQ A;  4KM2 A;  1DYH A;  6DFR A;  4P66 A;  3SRS X;  3N0H A;  4QLF A;  2W9S A;  3NU0 A;  2DRC A;  4FHB A;  3GYF A;  1DRF A;  4EIG A;  2W3W A;  4ELB A;  1YHO A;  1JOM A;  2W9T A;  5HQZ A;  3I3R A;  3FRF X;  1DR4 A;  5ECC A;  3UM8 A;  1RX7 A;  1J3J A;  3NXX A;  3IRO A;  3GHC A;  3R33 A;  4QJZ D;  3FRD X;  2BL9 A;  3DAT A;  3GI2 A;  1RB3 A;  4ELG A;  1S3V A;  3QYO A;  3FQV A;  1RB2 A;  4KBN A;  4OR7 A;  1BOZ A;  1DRH A;  4QI9 A;  3S3V A;  1DDS A;  3F91 A;  1U72 A;  4M7V A;  4XT8 A;  1SEJ A;  3M08 A;  1RA2 A;  1HFR A;  2INQ A;  2BLB A;  3QFX A;  3S7A A;  4M6J A;  1DR7 A;  4G3M A;  5EAJ A;  2B3Z A;  3DRC A;  1JUV A;  3NZD A;  5CC9 A;  3CL9 A;  3QL0 A;  3DFR A;  3JWK A;  4HA7 A;  1AI9 A;  3TQA A;  1LY3 A;  2H2Q A;  3ROA A;  1DR6 A;  1KMS A;  3KY8 A;  3SAI A;  5U26 A;  3GHW A;  3QLY A;  1RF7 A;  3JSU A;  5HI6 A;  1DR5 A;  2G6V A;  5HSU A;  3EEK A;  3TQB A;  2ITH A;  3SH2 A;  4DPD A;  5HF0 X;  4KY4 A;  2DHF A;  1DAJ A;  4Q6A A;  1DHI A;  1DRB A;  2XW7 A;  1PDB A;  3QL3 A;  1AOE A;  4PSS A;  1DYJ A;  3FL9 A;  3IX9 A;  4QLE A;  4KM0 A;  4P3R A;  1RG7 A;  1U70 A;  1DDR A;  3I8A X;  5HPB A;  2FZJ A;  2ANO A;  1M79 A;  1DG7 A;  4M6K A;  3FY9 X;  4H98 A;  3F0X X;  4KJJ A;  4X5J A;  4NX6 A;  4DP3 A;  3NZB X;  1RX8 A;  3FQF A;  3IA4 A;  1CD2 A;  5FDA A;  3NXY A;  3SRU X;  4HOF A;  5ECX A;  3EX8 A;  1U71 A;  4KYA A;  3SA2 A;  3F8Y A;  3IA5 A;  3F0B X;  1MVS A;  3CD2 A;  4KLX A;  3UM5 A;  3JVX A;  4Q67 A;  3NZ9 X;  3GHV A;  4QHV A;  3QLW A;  3HJ3 A;  2JYB A;  4HA9 A;  3SR5 X;  3QG2 A;  3TQ9 A;  3ZPC A;  4P68 A;  3F8Z A;  1HFP A;  3F0Q X;  1S3W A;  3FRE X;  5JG0 X;  3D80 A;  4I13 A;  2HQP A;  3JWM A;  4LEK X;  1AO8 A;  3JWF A;  1DG8 A;  4G95 A;  5E8Q A;  4XT6 A;  4ECK A;  4XE6 X;  1RA9 A;  3DG8 A;  1IA4 A;  2KGK A;  4ELH A;  3FQZ A;  3K47 A;  1LY4 A;  3OCH A;  1OHK A;  1LUD A;  4PTH A;  2QK8 A;  4GH8 A;  1DR1 A;  3FS6 A;  3NTZ A;  4H95 A;  3D84 X;  2BLA A;  4KJL A;  3F0U X;  1DYR A;  4EJ1 A;  3SA1 A;  4KJK A;  2L28 A;  4X5H A;  5HF2 X;  3JTW A;  4LAH X;  4XT7 A;  5HT4 A;  5HUI A;  3OAF A;  2GD9 A;  4RGC A;  2LF1 A;  4P3Q A;  1S3U A;  4XT4 A;  3IRN A;  3FY8 X;  3M09 A;  3SGY A;  3KJS A;  1MVT A;  2OIP A;  1RE7 A;  3LG4 A;  3CLB A;  5U27 A;  4XEC X;  4CD2 A;  3KJR A;  1RH3 A;  4X5F A;  3K74 A;  1DR3 A;  5HVE A;  4LAE X;  1E26 A;  1D1G A;  4EIL A;  3E0B A;  4FGG A;  4DPH A;  3JWC A;  4X5I A;  1M7A A;  1QZF A;  3FL8 A;  1RX4 A;  3VCO A;  1KLK A;  4LAG X;  4G8Z X;  2D5N A;  3EEJ A;  2BLC A;  1DF7 A;  1RX1 A;  4NX7 A;  3K45 A;  8DFR A;  3EEM A;  3KGY A;  3DGA A;  3ZPG A;  3FQO A;  1S3Y A;  3IRM A;  3RO9 A;  2W3B A;  1RA8 A;  3NXR A;  2W3M A;  3DAU A;  4Q0D A;  4DFR A;  1HFQ A;  3K2H A;  1DHF A;  3QGT A;  3L3R A;  1DLR A;  4KL9 A; 
#chains in the Genus database with same CATH homology
 3Q1H A;  5DXV A;  3QLX A;  2OBC A;  3TD8 A;  4PTJ A;  1M78 A;  1JOL A;  1DRE A;  1RX6 A;  4HOE A;  4IXE D;  2W3A A;  1CZ3 A;  4PDJ A;  3JW3 A;  2FZH A;  4EIZ A;  1PD8 A;  3JW5 A;  3KFY A;  3SRQ X;  4H96 A;  5HSR A;  2P4G A;  5HT5 A;  3UM6 A;  1PD9 A;  4QLG A;  2HM9 A;  1VDR A;  4H97 A;  2W9G A;  3RG9 A;  2C2S A;  7DFR A;  1RX9 A;  5CCC A;  3NZA X;  3CSE A;  3NRR A;  3NZC X;  1VJ3 A;  4KY8 A;  3QYL A;  4TU5 X;  1BZF A;  3SRW X;  3QLR A;  4KEB A;  3NXT A;  4PSY A;  1IA1 A;  1DHJ A;  3QLS A;  3QLZ A;  3SQY X;  1RX5 A;  3NXO A;  5HVB A;  4HOG A;  4ELF A;  4FGH A;  2AZN A;  3FRA X;  4KNE A;  3DL6 A;  3EIG A;  1DG5 A;  3FRB X;  1J3K A;  1J3I A;  2HXV A;  4Q0E A;  4M7U A;  3S9U A;  3F0V X;  5HQY A;  4OSG A;  1DIS A;  3FYW X;  2CD2 A;  4ELE A;  3EEL A;  4DDR A;  1RX3 A;  4PST A;  2W9H A;  3FQC A;  1DLS A;  1RX2 A;  1RC4 A;  4I1N A;  4M6L A;  3SRR X;  4KAK A;  2ZZA A;  3NZ6 X;  1KMV A;  2C2T A;  5DFR A;  1IA3 A;  2D0K A;  4IXG X;  4M2X A;  4KFJ A;  1DYI A;  1TDR A;  3NXV A;  4KD7 A;  3FQ0 A;  1DR2 A;  3DL5 A;  5JA3 A;  2FZI A;  1DRA A;  4QJC A;  1DIU A;  1RD7 A;  1RA1 A;  1RA3 A;  4XT5 A;  2CIG A;  2W3V A;  4XRB A;  3HBB A;  1ZDR A;  3F0S X;  2O7P A;  3FYV X;  1IA2 A;  3INV A;  3TQ8 A;  4X5G A;  4IXF X;  1OHJ A;  2ANQ A;  4KM2 A;  1DYH A;  6DFR A;  4P66 A;  3SRS X;  3N0H A;  4QLF A;  2W9S A;  3NU0 A;  2DRC A;  4FHB A;  3GYF A;  1DRF A;  4EIG A;  2W3W A;  4ELB A;  1YHO A;  1JOM A;  2W9T A;  5HQZ A;  3I3R A;  3FRF X;  1DR4 A;  5ECC A;  3UM8 A;  1RX7 A;  1J3J A;  3NXX A;  3IRO A;  3GHC A;  3R33 A;  4QJZ D;  3FRD X;  2BL9 A;  3DAT A;  3GI2 A;  1RB3 A;  4ELG A;  1S3V A;  3QYO A;  3FQV A;  1RB2 A;  4KBN A;  4OR7 A;  1BOZ A;  1DRH A;  4QI9 A;  3S3V A;  1DDS A;  3F91 A;  1U72 A;  4M7V A;  4XT8 A;  1SEJ A;  3M08 A;  1RA2 A;  1HFR A;  2INQ A;  2BLB A;  3QFX A;  3S7A A;  4M6J A;  1DR7 A;  4G3M A;  5EAJ A;  2B3Z A;  3DRC A;  1JUV A;  3NZD A;  5CC9 A;  3CL9 A;  3QL0 A;  3DFR A;  3JWK A;  4HA7 A;  1AI9 A;  3TQA A;  1LY3 A;  2H2Q A;  3ROA A;  1DR6 A;  1KMS A;  3KY8 A;  3SAI A;  5U26 A;  3GHW A;  3QLY A;  1RF7 A;  3JSU A;  5HI6 A;  1DR5 A;  2G6V A;  5HSU A;  3EEK A;  3TQB A;  2ITH A;  3SH2 A;  4DPD A;  5HF0 X;  4KY4 A;  2DHF A;  1DAJ A;  4Q6A A;  1DHI A;  1DRB A;  2XW7 A;  1PDB A;  3QL3 A;  1AOE A;  4PSS A;  1DYJ A;  3FL9 A;  3IX9 A;  4QLE A;  4KM0 A;  4P3R A;  1RG7 A;  1U70 A;  1DDR A;  3I8A X;  5HPB A;  2FZJ A;  2ANO A;  1M79 A;  1DG7 A;  4M6K A;  3FY9 X;  4H98 A;  3F0X X;  4KJJ A;  4X5J A;  4NX6 A;  4DP3 A;  3NZB X;  1RX8 A;  3FQF A;  3IA4 A;  1CD2 A;  5FDA A;  3NXY A;  3SRU X;  4HOF A;  5ECX A;  3EX8 A;  1U71 A;  4KYA A;  3SA2 A;  3F8Y A;  3IA5 A;  3F0B X;  1MVS A;  3CD2 A;  4KLX A;  3UM5 A;  3JVX A;  4Q67 A;  3NZ9 X;  3GHV A;  4QHV A;  3QLW A;  3HJ3 A;  2JYB A;  4HA9 A;  3SR5 X;  3QG2 A;  3TQ9 A;  3ZPC A;  4P68 A;  3F8Z A;  1HFP A;  3F0Q X;  1S3W A;  3FRE X;  5JG0 X;  3D80 A;  4I13 A;  2HQP A;  3JWM A;  4LEK X;  1AO8 A;  3JWF A;  1DG8 A;  4G95 A;  5E8Q A;  4XT6 A;  4ECK A;  4XE6 X;  1RA9 A;  3DG8 A;  1IA4 A;  2KGK A;  4ELH A;  3FQZ A;  3K47 A;  1LY4 A;  3OCH A;  1OHK A;  1LUD A;  4PTH A;  2QK8 A;  4GH8 A;  1DR1 A;  3FS6 A;  3NTZ A;  4H95 A;  3D84 X;  2BLA A;  4KJL A;  3F0U X;  1DYR A;  4EJ1 A;  3SA1 A;  4KJK A;  2L28 A;  4X5H A;  5HF2 X;  3JTW A;  4LAH X;  4XT7 A;  5HT4 A;  5HUI A;  3OAF A;  2GD9 A;  4RGC A;  2LF1 A;  4P3Q A;  1S3U A;  4XT4 A;  3IRN A;  3FY8 X;  3M09 A;  3SGY A;  3KJS A;  1MVT A;  2OIP A;  1RE7 A;  3LG4 A;  3CLB A;  5U27 A;  4XEC X;  4CD2 A;  3KJR A;  1RH3 A;  4X5F A;  3K74 A;  1DR3 A;  5HVE A;  4LAE X;  1E26 A;  1D1G A;  4EIL A;  3E0B A;  4FGG A;  4DPH A;  3JWC A;  4X5I A;  1M7A A;  1QZF A;  3FL8 A;  1RX4 A;  3VCO A;  1KLK A;  4LAG X;  4G8Z X;  2D5N A;  3EEJ A;  2BLC A;  1DF7 A;  1RX1 A;  4NX7 A;  3K45 A;  8DFR A;  3EEM A;  3KGY A;  3DGA A;  3ZPG A;  3FQO A;  1S3Y A;  3IRM A;  3RO9 A;  2W3B A;  1RA8 A;  3NXR A;  2W3M A;  3DAU A;  4Q0D A;  4DFR A;  1HFQ A;  3K2H A;  1DHF A;  3QGT A;  3L3R A;  1DLR A;  4KL9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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