4G8ZX

Pcdhfr k37s/f69n double mutant tmp nadph ternary complex
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
204
structure length
204
Chain Sequence
QQKSLTLIVALTTSYGIGRSNSLPWKLKKEISYFSRVTSFVPTFDSFESMNVVLMGRKTWESIPLQNRPLKGRINVVITRNAAAAAAAAIHSAKSLDHALELLYRTYGSESSVQINRIFVIGGAQLYKAAMDHPKLDRIMATIIYKDIHCDVFFPLKFRDKEWSSVWKKEKHSDLESWVGTKVPHGKINEDGFDYEFEMWTRDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Kinetic and Structural Analysis for Potent Antifolate Inhibition of Pneumocystis jirovecii, Pneumocystis carinii, and Human Dihydrofolate Reductases and Their Active-Site Variants.
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Pneumocystis jirovecii
molecule keywords Dihydrofolate reductase
total genus 56
structure length 204
sequence length 204
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2012-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4g8zX00
1PD9A 3QFXA 3VCOA 3JW5A 3N0HA 3KGYA 1DR1A 1KMSA 3FRAX 1SEJA 2OIPA 5HUIA 2C2TA 1RX1A 4ELFA 2BLCA 2W3WA 3NZDA 4M7VA 3NZBX 1IA3A 3KY8A 2CD2A 3FQVA 5EAJA 3GHCA 3FS6A 1J3IA 4X5HA 3SAIA 2H2QA 3NRRA 4NX7A 3D84X 4Q0EA 1LY3A 3QLWA 3GYFA 2ZZAA 4DPHA 2BLBA 3TQ8A 1S3WA 4XT8A 1IA1A 2INQA 3QGTA 1DRFA 4TU5X 1DISA 1CD2A 3OCHA 2FZHA 4IXGX 5JA3A 4QLGA 3SH2A 1MVTA 3R33A 5HSRA 2QK8A 2JYBA 3GI2A 4GH8A 5DXVA 1JOLA 3SRQX 3NZ6X 4H97A 3EELA 1S3YA 5DFRA 4QI9A 2FZIA 3DL6A 3FY9X 2DHFA 4X5JA 5ECXA 3TQBA 3D80A 5CCCA 3NXOA 4KD7A 4KL9A 2P4GA 5HF2X 5FDAA 4P66A 2L28A 2W9HA 3M09A 5JG0X 1KMVA 1VJ3A 1DDRA 2W3BA 3NZAX 3NZ9X 1RX5A 5HI6A 2DRCA 5HVEA 1RX3A 3JSUA 3OAFA 4ELGA 3DRCA 4EILA 3UM8A 1DG8A 3TQAA 3KFYA 4HA7A 2LF1A 3SRUX 4KYAA 3EEJA 5ECCA 2W9TA 3GHWA 8DFRA 3JTWA 3F0QX 4LAEX 1KLKA 3FRDX 4M6LA 4KY8A 3FRBX 4P68A 2G6VA 2W9GA 4KEBA 4PSTA 4I1NA 1DR2A 4FHBA 4DFRA 2KGKA 3K74A 1DYJA 1RE7A 1RX2A 4M6KA 4ECKA 1DG5A 3SRRX 3SRSX 3INVA 3FL9A 3FY8X 3K2HA 3NZCX 1RA9A 1HFQA 1U71A 3FQOA 3Q1HA 1DYIA 4DP3A 4OSGA 3IRMA 1DLRA 1RC4A 4G3MA 3ZPGA 3SA2A 3F0UX 3QLYA 3QYOA 3K45A 1JUVA 4X5IA 1E26A 3M08A 4PSYA 1DRBA 2W3VA 1DF7A 1RG7A 4LAHX 2HXVA 4KJJA 3UM6A 1JOMA 4KAKA 3RO9A 3NXXA 1BOZA 1M78A 4KNEA 4HA9A 2BL9A 4XT5A 1DREA 7DFRA 3QLSA 3QYLA 3F91A 1IA2A 3IA5A 1DIUA 4KY4A 4KJLA 3FRFX 2W9SA 3I8AX 3FREX 4H96A 1DR5A 1RX4A 3FQCA 4Q6AA 1VDRA 4NX6A 2HM9A 4HOGA 1DRHA 1DYHA 2D5NA 3QL3A 1RH3A 2OBCA 1RB3A 3IA4A 2O7PA 4IXED 3CSEA 4KBNA 4XT6A 3FYVX 3QLRA 1BZFA 3KJSA 4P3RA 3NXRA 4ELHA 3FQZA 3E0BA 1M7AA 1PDBA 3JWKA 3DGAA 5HT5A 1OHJA 3QLXA 1PD8A 3SGYA 4X5GA 2C2SA 1ZDRA 1RX9A 3F0BX 1DR6A 1J3JA 4RGCA 4EIZA 4Q67A 5HT4A 1HFRA 3SA1A 1M79A 3QL0A 4LEKX 1U70A 4QHVA 3DFRA 3SRWX 1RX6A 4QLFA 1AI9A 1RD7A 4LAGX 4CD2A 3EEKA 2AZNA 3NXVA 2CIGA 3DG8A 2ANQA 4PDJA 5HF0X 3F0VX 6DFRA 5HQZA 5HQYA 1CZ3A 2ITHA 3JWMA 4P3QA 4QJCA 3NU0A 3SQYX 2ANOA 1DRAA 3TQ9A 3S9UA 3DAUA 1RX8A 1DHIA 4PTHA 4EIGA 1DG7A 1U72A 1J3KA 1DR3A 2W3MA 4ELBA 1LY4A 3JVXA 4G95A 3UM5A 1QZFA 3LG4A 3QLZA 3FL8A 5U27A 5U26A 3FQFA 4DDRA 1OHKA 3F0XX 3K47A 1D1GA 4I13A 4HOFA 1DR7A 4FGHA 1YHOA 3S7AA 5HSUA 3F8YA 3HJ3A 4M2XA 1DAJA 4KLXA 1DDSA 4KM0A 4G8ZX 4FGGA 4HOEA 3JWCA 5E8QA 4H98A 4XRBA 3CD2A 1RF7A 4X5FA 4PTJA 3CLBA 4OR7A 3KJRA 1RA8A 1IA4A 1RB2A 2W3AA 3JWFA 4XT7A 4M6JA 1AOEA 5HVBA 5CC9A 4KFJA 4QJZD 1RA2A 3FYWX 1DLSA 4IXFX 1RA1A 3IRNA 1TDRA 3IROA 2BLAA 3F8ZA 3EEMA 3F0SX 3IX9A 4PSSA 3I3RA 3S3VA 5HPBA 1DR4A 1MVSA 4XECX 3GHVA 1AO8A 3RG9A 2XW7A 4QLEA 1DYRA 3L3RA 1RX7A 3CL9A 2HQPA 4XE6X 1S3UA 3QG2A 2GD9A 3DATA 4EJ1A 4M7UA 2D0KA 3SR5X 3DL5A 3NXTA 3EX8A 4XT4A 3FQ0A 2FZJA 3TD8A 4KJKA 4Q0DA 1RA3A 1DHFA 3HBBA 3JW3A 4DPDA 1LUDA 1HFPA 3NTZA 4KM2A 3NXYA 3EIGA 1S3VA 3ROAA 4H95A 3ZPCA 4ELEA 1DHJA 2B3ZA
chains in the Genus database with same CATH superfamily
1PD9A 3QFXA 3VCOA 3JW5A 3N0HA 3KGYA 1DR1A 1KMSA 3FRAX 1SEJA 2OIPA 5HUIA 2C2TA 1RX1A 4ELFA 2BLCA 2W3WA 3NZDA 4M7VA 3NZBX 1IA3A 3KY8A 2CD2A 3FQVA 5EAJA 3GHCA 3FS6A 1J3IA 4X5HA 3SAIA 2H2QA 3NRRA 4NX7A 3D84X 4Q0EA 1LY3A 3QLWA 3GYFA 2ZZAA 4DPHA 2BLBA 3TQ8A 1S3WA 4XT8A 1IA1A 2INQA 3QGTA 1DRFA 4TU5X 1DISA 1CD2A 3OCHA 2FZHA 4IXGX 5JA3A 4QLGA 3SH2A 1MVTA 3R33A 5HSRA 2QK8A 2JYBA 3GI2A 4GH8A 5DXVA 1JOLA 3SRQX 3NZ6X 4H97A 3EELA 1S3YA 5DFRA 4QI9A 2FZIA 3DL6A 3FY9X 2DHFA 4X5JA 5ECXA 3TQBA 3D80A 5CCCA 3NXOA 4KD7A 4KL9A 2P4GA 5HF2X 5FDAA 4P66A 2L28A 2W9HA 3M09A 5JG0X 1KMVA 1VJ3A 1DDRA 2W3BA 3NZAX 3NZ9X 1RX5A 5HI6A 2DRCA 5HVEA 1RX3A 3JSUA 3OAFA 4ELGA 3DRCA 4EILA 3UM8A 1DG8A 3TQAA 3KFYA 4HA7A 2LF1A 3SRUX 4KYAA 3EEJA 5ECCA 2W9TA 3GHWA 8DFRA 3JTWA 3F0QX 4LAEX 1KLKA 3FRDX 4M6LA 4KY8A 3FRBX 4P68A 2G6VA 2W9GA 4KEBA 4PSTA 4I1NA 1DR2A 4FHBA 4DFRA 2KGKA 3K74A 1DYJA 1RE7A 1RX2A 4M6KA 4ECKA 1DG5A 3SRRX 3SRSX 3INVA 3FL9A 3FY8X 3K2HA 3NZCX 1RA9A 1HFQA 1U71A 3FQOA 3Q1HA 1DYIA 4DP3A 4OSGA 3IRMA 1DLRA 1RC4A 4G3MA 3ZPGA 3SA2A 3F0UX 3QLYA 3QYOA 3K45A 1JUVA 4X5IA 1E26A 3M08A 4PSYA 1DRBA 2W3VA 1DF7A 1RG7A 4LAHX 2HXVA 4KJJA 3UM6A 1JOMA 4KAKA 3RO9A 3NXXA 1BOZA 1M78A 4KNEA 4HA9A 2BL9A 4XT5A 1DREA 7DFRA 3QLSA 3QYLA 3F91A 1IA2A 3IA5A 1DIUA 4KY4A 4KJLA 3FRFX 2W9SA 3I8AX 3FREX 4H96A 1DR5A 1RX4A 3FQCA 4Q6AA 1VDRA 4NX6A 2HM9A 4HOGA 1DRHA 1DYHA 2D5NA 3QL3A 1RH3A 2OBCA 1RB3A 3IA4A 2O7PA 4IXED 3CSEA 4KBNA 4XT6A 3FYVX 3QLRA 1BZFA 3KJSA 4P3RA 3NXRA 4ELHA 3FQZA 3E0BA 1M7AA 1PDBA 3JWKA 3DGAA 5HT5A 1OHJA 3QLXA 1PD8A 3SGYA 4X5GA 2C2SA 1ZDRA 1RX9A 3F0BX 1DR6A 1J3JA 4RGCA 4EIZA 4Q67A 5HT4A 1HFRA 3SA1A 1M79A 3QL0A 4LEKX 1U70A 4QHVA 3DFRA 3SRWX 1RX6A 4QLFA 1AI9A 1RD7A 4LAGX 4CD2A 3EEKA 2AZNA 3NXVA 2CIGA 3DG8A 2ANQA 4PDJA 5HF0X 3F0VX 6DFRA 5HQZA 5HQYA 1CZ3A 2ITHA 3JWMA 4P3QA 4QJCA 3NU0A 3SQYX 2ANOA 1DRAA 3TQ9A 3S9UA 3DAUA 1RX8A 1DHIA 4PTHA 4EIGA 1DG7A 1U72A 1J3KA 1DR3A 2W3MA 4ELBA 1LY4A 3JVXA 4G95A 3UM5A 1QZFA 3LG4A 3QLZA 3FL8A 5U27A 5U26A 3FQFA 4DDRA 1OHKA 3F0XX 3K47A 1D1GA 4I13A 4HOFA 1DR7A 4FGHA 1YHOA 3S7AA 5HSUA 3F8YA 3HJ3A 4M2XA 1DAJA 4KLXA 1DDSA 4KM0A 4G8ZX 4FGGA 4HOEA 3JWCA 5E8QA 4H98A 4XRBA 3CD2A 1RF7A 4X5FA 4PTJA 3CLBA 4OR7A 3KJRA 1RA8A 1IA4A 1RB2A 2W3AA 3JWFA 4XT7A 4M6JA 1AOEA 5HVBA 5CC9A 4KFJA 4QJZD 1RA2A 3FYWX 1DLSA 4IXFX 1RA1A 3IRNA 1TDRA 3IROA 2BLAA 3F8ZA 3EEMA 3F0SX 3IX9A 4PSSA 3I3RA 3S3VA 5HPBA 1DR4A 1MVSA 4XECX 3GHVA 1AO8A 3RG9A 2XW7A 4QLEA 1DYRA 3L3RA 1RX7A 3CL9A 2HQPA 4XE6X 1S3UA 3QG2A 2GD9A 3DATA 4EJ1A 4M7UA 2D0KA 3SR5X 3DL5A 3NXTA 3EX8A 4XT4A 3FQ0A 2FZJA 3TD8A 4KJKA 4Q0DA 1RA3A 1DHFA 3HBBA 3JW3A 4DPDA 1LUDA 1HFPA 3NTZA 4KM2A 3NXYA 3EIGA 1S3VA 3ROAA 4H95A 3ZPCA 4ELEA 1DHJA 2B3ZA
chains in the Genus database with same CATH topology
1PD9A 3QFXA 3VCOA 3JW5A 3N0HA 3KGYA 1DR1A 1KMSA 3FRAX 1SEJA 2OIPA 5HUIA 2C2TA 1RX1A 4ELFA 2BLCA 2W3WA 3NZDA 4M7VA 3NZBX 1IA3A 3KY8A 2CD2A 3FQVA 5EAJA 3GHCA 3FS6A 1J3IA 4X5HA 3SAIA 2H2QA 3NRRA 4NX7A 3D84X 4Q0EA 1LY3A 3QLWA 3GYFA 2ZZAA 4DPHA 2BLBA 3TQ8A 1S3WA 4XT8A 1IA1A 2INQA 3QGTA 1DRFA 4TU5X 1DISA 1CD2A 3OCHA 2FZHA 4IXGX 5JA3A 4QLGA 3SH2A 1MVTA 3R33A 5HSRA 2QK8A 2JYBA 3GI2A 4GH8A 5DXVA 1JOLA 3SRQX 3NZ6X 4H97A 3EELA 1S3YA 5DFRA 4QI9A 2FZIA 3DL6A 3FY9X 2DHFA 4X5JA 5ECXA 3TQBA 3D80A 5CCCA 3NXOA 4KD7A 4KL9A 2P4GA 5HF2X 5FDAA 4P66A 2L28A 2W9HA 3M09A 5JG0X 1KMVA 1VJ3A 1DDRA 2W3BA 3NZAX 3NZ9X 1RX5A 5HI6A 2DRCA 5HVEA 1RX3A 3JSUA 3OAFA 4ELGA 3DRCA 4EILA 3UM8A 1DG8A 3TQAA 3KFYA 4HA7A 2LF1A 3SRUX 4KYAA 3EEJA 5ECCA 2W9TA 3GHWA 8DFRA 3JTWA 3F0QX 4LAEX 1KLKA 3FRDX 4M6LA 4KY8A 3FRBX 4P68A 2G6VA 2W9GA 4KEBA 4PSTA 4I1NA 1DR2A 4FHBA 4DFRA 2KGKA 3K74A 1DYJA 1RE7A 1RX2A 4M6KA 4ECKA 1DG5A 3SRRX 3SRSX 3INVA 3FL9A 3FY8X 3K2HA 3NZCX 1RA9A 1HFQA 1U71A 3FQOA 3Q1HA 1DYIA 4DP3A 4OSGA 3IRMA 1DLRA 1RC4A 4G3MA 3ZPGA 3SA2A 3F0UX 3QLYA 3QYOA 3K45A 1JUVA 4X5IA 1E26A 3M08A 4PSYA 1DRBA 2W3VA 1DF7A 1RG7A 4LAHX 2HXVA 4KJJA 3UM6A 1JOMA 4KAKA 3RO9A 3NXXA 1BOZA 1M78A 4KNEA 4HA9A 2BL9A 4XT5A 1DREA 7DFRA 3QLSA 3QYLA 3F91A 1IA2A 3IA5A 1DIUA 4KY4A 4KJLA 3FRFX 2W9SA 3I8AX 3FREX 4H96A 1DR5A 1RX4A 3FQCA 4Q6AA 1VDRA 4NX6A 2HM9A 4HOGA 1DRHA 1DYHA 2D5NA 3QL3A 1RH3A 2OBCA 1RB3A 3IA4A 2O7PA 4IXED 3CSEA 4KBNA 4XT6A 3FYVX 3QLRA 1BZFA 3KJSA 4P3RA 3NXRA 4ELHA 3FQZA 3E0BA 1M7AA 1PDBA 3JWKA 3DGAA 5HT5A 1OHJA 3QLXA 1PD8A 3SGYA 4X5GA 2C2SA 1ZDRA 1RX9A 3F0BX 1DR6A 1J3JA 4RGCA 4EIZA 4Q67A 5HT4A 1HFRA 3SA1A 1M79A 3QL0A 4LEKX 1U70A 4QHVA 3DFRA 3SRWX 1RX6A 4QLFA 1AI9A 1RD7A 4LAGX 4CD2A 3EEKA 2AZNA 3NXVA 2CIGA 3DG8A 2ANQA 4PDJA 5HF0X 3F0VX 6DFRA 5HQZA 5HQYA 1CZ3A 2ITHA 3JWMA 4P3QA 4QJCA 3NU0A 3SQYX 2ANOA 1DRAA 3TQ9A 3S9UA 3DAUA 1RX8A 1DHIA 4PTHA 4EIGA 1DG7A 1U72A 1J3KA 1DR3A 2W3MA 4ELBA 1LY4A 3JVXA 4G95A 3UM5A 1QZFA 3LG4A 3QLZA 3FL8A 5U27A 5U26A 3FQFA 4DDRA 1OHKA 3F0XX 3K47A 1D1GA 4I13A 4HOFA 1DR7A 4FGHA 1YHOA 3S7AA 5HSUA 3F8YA 3HJ3A 4M2XA 1DAJA 4KLXA 1DDSA 4KM0A 4G8ZX 4FGGA 4HOEA 3JWCA 5E8QA 4H98A 4XRBA 3CD2A 1RF7A 4X5FA 4PTJA 3CLBA 4OR7A 3KJRA 1RA8A 1IA4A 1RB2A 2W3AA 3JWFA 4XT7A 4M6JA 1AOEA 5HVBA 5CC9A 4KFJA 4QJZD 1RA2A 3FYWX 1DLSA 4IXFX 1RA1A 3IRNA 1TDRA 3IROA 2BLAA 3F8ZA 3EEMA 3F0SX 3IX9A 4PSSA 3I3RA 3S3VA 5HPBA 1DR4A 1MVSA 4XECX 3GHVA 1AO8A 3RG9A 2XW7A 4QLEA 1DYRA 3L3RA 1RX7A 3CL9A 2HQPA 4XE6X 1S3UA 3QG2A 2GD9A 3DATA 4EJ1A 4M7UA 2D0KA 3SR5X 3DL5A 3NXTA 3EX8A 4XT4A 3FQ0A 2FZJA 3TD8A 4KJKA 4Q0DA 1RA3A 1DHFA 3HBBA 3JW3A 4DPDA 1LUDA 1HFPA 3NTZA 4KM2A 3NXYA 3EIGA 1S3VA 3ROAA 4H95A 3ZPCA 4ELEA 1DHJA 2B3ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PD9 A;  3QFX A;  3VCO A;  3JW5 A;  3N0H A;  3KGY A;  1DR1 A;  1KMS A;  3FRA X;  1SEJ A;  2OIP A;  5HUI A;  2C2T A;  1RX1 A;  4ELF A;  2BLC A;  2W3W A;  3NZD A;  4M7V A;  3NZB X;  1IA3 A;  3KY8 A;  2CD2 A;  3FQV A;  5EAJ A;  3GHC A;  3FS6 A;  1J3I A;  4X5H A;  3SAI A;  2H2Q A;  3NRR A;  4NX7 A;  3D84 X;  4Q0E A;  1LY3 A;  3QLW A;  3GYF A;  2ZZA A;  4DPH A;  2BLB A;  3TQ8 A;  1S3W A;  4XT8 A;  1IA1 A;  2INQ A;  3QGT A;  1DRF A;  4TU5 X;  1DIS A;  1CD2 A;  3OCH A;  2FZH A;  4IXG X;  5JA3 A;  4QLG A;  3SH2 A;  1MVT A;  3R33 A;  5HSR A;  2QK8 A;  2JYB A;  3GI2 A;  4GH8 A;  5DXV A;  1JOL A;  3SRQ X;  3NZ6 X;  4H97 A;  3EEL A;  1S3Y A;  5DFR A;  4QI9 A;  2FZI A;  3DL6 A;  3FY9 X;  2DHF A;  4X5J A;  5ECX A;  3TQB A;  3D80 A;  5CCC A;  3NXO A;  4KD7 A;  4KL9 A;  2P4G A;  5HF2 X;  5FDA A;  4P66 A;  2L28 A;  2W9H A;  3M09 A;  5JG0 X;  1KMV A;  1VJ3 A;  1DDR A;  2W3B A;  3NZA X;  3NZ9 X;  1RX5 A;  5HI6 A;  2DRC A;  5HVE A;  1RX3 A;  3JSU A;  3OAF A;  4ELG A;  3DRC A;  4EIL A;  3UM8 A;  1DG8 A;  3TQA A;  3KFY A;  4HA7 A;  2LF1 A;  3SRU X;  4KYA A;  3EEJ A;  5ECC A;  2W9T A;  3GHW A;  8DFR A;  3JTW A;  3F0Q X;  4LAE X;  1KLK A;  3FRD X;  4M6L A;  4KY8 A;  3FRB X;  4P68 A;  2G6V A;  2W9G A;  4KEB A;  4PST A;  4I1N A;  1DR2 A;  4FHB A;  4DFR A;  2KGK A;  3K74 A;  1DYJ A;  1RE7 A;  1RX2 A;  4M6K A;  4ECK A;  1DG5 A;  3SRR X;  3SRS X;  3INV A;  3FL9 A;  3FY8 X;  3K2H A;  3NZC X;  1RA9 A;  1HFQ A;  1U71 A;  3FQO A;  3Q1H A;  1DYI A;  4DP3 A;  4OSG A;  3IRM A;  1DLR A;  1RC4 A;  4G3M A;  3ZPG A;  3SA2 A;  3F0U X;  3QLY A;  3QYO A;  3K45 A;  1JUV A;  4X5I A;  1E26 A;  3M08 A;  4PSY A;  1DRB A;  2W3V A;  1DF7 A;  1RG7 A;  4LAH X;  2HXV A;  4KJJ A;  3UM6 A;  1JOM A;  4KAK A;  3RO9 A;  3NXX A;  1BOZ A;  1M78 A;  4KNE A;  4HA9 A;  2BL9 A;  4XT5 A;  1DRE A;  7DFR A;  3QLS A;  3QYL A;  3F91 A;  1IA2 A;  3IA5 A;  1DIU A;  4KY4 A;  4KJL A;  3FRF X;  2W9S A;  3I8A X;  3FRE X;  4H96 A;  1DR5 A;  1RX4 A;  3FQC A;  4Q6A A;  1VDR A;  4NX6 A;  2HM9 A;  4HOG A;  1DRH A;  1DYH A;  2D5N A;  3QL3 A;  1RH3 A;  2OBC A;  1RB3 A;  3IA4 A;  2O7P A;  4IXE D;  3CSE A;  4KBN A;  4XT6 A;  3FYV X;  3QLR A;  1BZF A;  3KJS A;  4P3R A;  3NXR A;  4ELH A;  3FQZ A;  3E0B A;  1M7A A;  1PDB A;  3JWK A;  3DGA A;  5HT5 A;  1OHJ A;  3QLX A;  1PD8 A;  3SGY A;  4X5G A;  2C2S A;  1ZDR A;  1RX9 A;  3F0B X;  1DR6 A;  1J3J A;  4RGC A;  4EIZ A;  4Q67 A;  5HT4 A;  1HFR A;  3SA1 A;  1M79 A;  3QL0 A;  4LEK X;  1U70 A;  4QHV A;  3DFR A;  3SRW X;  1RX6 A;  4QLF A;  1AI9 A;  1RD7 A;  4LAG X;  4CD2 A;  3EEK A;  2AZN A;  3NXV A;  2CIG A;  3DG8 A;  2ANQ A;  4PDJ A;  5HF0 X;  3F0V X;  6DFR A;  5HQZ A;  5HQY A;  1CZ3 A;  2ITH A;  3JWM A;  4P3Q A;  4QJC A;  3NU0 A;  3SQY X;  2ANO A;  1DRA A;  3TQ9 A;  3S9U A;  3DAU A;  1RX8 A;  1DHI A;  4PTH A;  4EIG A;  1DG7 A;  1U72 A;  1J3K A;  1DR3 A;  2W3M A;  4ELB A;  1LY4 A;  3JVX A;  4G95 A;  3UM5 A;  1QZF A;  3LG4 A;  3QLZ A;  3FL8 A;  5U27 A;  5U26 A;  3FQF A;  4DDR A;  1OHK A;  3F0X X;  3K47 A;  1D1G A;  4I13 A;  4HOF A;  1DR7 A;  4FGH A;  1YHO A;  3S7A A;  5HSU A;  3F8Y A;  3HJ3 A;  4M2X A;  1DAJ A;  4KLX A;  1DDS A;  4KM0 A;  4G8Z X;  4FGG A;  4HOE A;  3JWC A;  5E8Q A;  4H98 A;  4XRB A;  3CD2 A;  1RF7 A;  4X5F A;  4PTJ A;  3CLB A;  4OR7 A;  3KJR A;  1RA8 A;  1IA4 A;  1RB2 A;  2W3A A;  3JWF A;  4XT7 A;  4M6J A;  1AOE A;  5HVB A;  5CC9 A;  4KFJ A;  4QJZ D;  1RA2 A;  3FYW X;  1DLS A;  4IXF X;  1RA1 A;  3IRN A;  1TDR A;  3IRO A;  2BLA A;  3F8Z A;  3EEM A;  3F0S X;  3IX9 A;  4PSS A;  3I3R A;  3S3V A;  5HPB A;  1DR4 A;  1MVS A;  4XEC X;  3GHV A;  1AO8 A;  3RG9 A;  2XW7 A;  4QLE A;  1DYR A;  3L3R A;  1RX7 A;  3CL9 A;  2HQP A;  4XE6 X;  1S3U A;  3QG2 A;  2GD9 A;  3DAT A;  4EJ1 A;  4M7U A;  2D0K A;  3SR5 X;  3DL5 A;  3NXT A;  3EX8 A;  4XT4 A;  3FQ0 A;  2FZJ A;  3TD8 A;  4KJK A;  4Q0D A;  1RA3 A;  1DHF A;  3HBB A;  3JW3 A;  4DPD A;  1LUD A;  1HFP A;  3NTZ A;  4KM2 A;  3NXY A;  3EIG A;  1S3V A;  3ROA A;  4H95 A;  3ZPC A;  4ELE A;  1DHJ A;  2B3Z A; 
#chains in the Genus database with same CATH topology
 1PD9 A;  3QFX A;  3VCO A;  3JW5 A;  3N0H A;  3KGY A;  1DR1 A;  1KMS A;  3FRA X;  1SEJ A;  2OIP A;  5HUI A;  2C2T A;  1RX1 A;  4ELF A;  2BLC A;  2W3W A;  3NZD A;  4M7V A;  3NZB X;  1IA3 A;  3KY8 A;  2CD2 A;  3FQV A;  5EAJ A;  3GHC A;  3FS6 A;  1J3I A;  4X5H A;  3SAI A;  2H2Q A;  3NRR A;  4NX7 A;  3D84 X;  4Q0E A;  1LY3 A;  3QLW A;  3GYF A;  2ZZA A;  4DPH A;  2BLB A;  3TQ8 A;  1S3W A;  4XT8 A;  1IA1 A;  2INQ A;  3QGT A;  1DRF A;  4TU5 X;  1DIS A;  1CD2 A;  3OCH A;  2FZH A;  4IXG X;  5JA3 A;  4QLG A;  3SH2 A;  1MVT A;  3R33 A;  5HSR A;  2QK8 A;  2JYB A;  3GI2 A;  4GH8 A;  5DXV A;  1JOL A;  3SRQ X;  3NZ6 X;  4H97 A;  3EEL A;  1S3Y A;  5DFR A;  4QI9 A;  2FZI A;  3DL6 A;  3FY9 X;  2DHF A;  4X5J A;  5ECX A;  3TQB A;  3D80 A;  5CCC A;  3NXO A;  4KD7 A;  4KL9 A;  2P4G A;  5HF2 X;  5FDA A;  4P66 A;  2L28 A;  2W9H A;  3M09 A;  5JG0 X;  1KMV A;  1VJ3 A;  1DDR A;  2W3B A;  3NZA X;  3NZ9 X;  1RX5 A;  5HI6 A;  2DRC A;  5HVE A;  1RX3 A;  3JSU A;  3OAF A;  4ELG A;  3DRC A;  4EIL A;  3UM8 A;  1DG8 A;  3TQA A;  3KFY A;  4HA7 A;  2LF1 A;  3SRU X;  4KYA A;  3EEJ A;  5ECC A;  2W9T A;  3GHW A;  8DFR A;  3JTW A;  3F0Q X;  4LAE X;  1KLK A;  3FRD X;  4M6L A;  4KY8 A;  3FRB X;  4P68 A;  2G6V A;  2W9G A;  4KEB A;  4PST A;  4I1N A;  1DR2 A;  4FHB A;  4DFR A;  2KGK A;  3K74 A;  1DYJ A;  1RE7 A;  1RX2 A;  4M6K A;  4ECK A;  1DG5 A;  3SRR X;  3SRS X;  3INV A;  3FL9 A;  3FY8 X;  3K2H A;  3NZC X;  1RA9 A;  1HFQ A;  1U71 A;  3FQO A;  3Q1H A;  1DYI A;  4DP3 A;  4OSG A;  3IRM A;  1DLR A;  1RC4 A;  4G3M A;  3ZPG A;  3SA2 A;  3F0U X;  3QLY A;  3QYO A;  3K45 A;  1JUV A;  4X5I A;  1E26 A;  3M08 A;  4PSY A;  1DRB A;  2W3V A;  1DF7 A;  1RG7 A;  4LAH X;  2HXV A;  4KJJ A;  3UM6 A;  1JOM A;  4KAK A;  3RO9 A;  3NXX A;  1BOZ A;  1M78 A;  4KNE A;  4HA9 A;  2BL9 A;  4XT5 A;  1DRE A;  7DFR A;  3QLS A;  3QYL A;  3F91 A;  1IA2 A;  3IA5 A;  1DIU A;  4KY4 A;  4KJL A;  3FRF X;  2W9S A;  3I8A X;  3FRE X;  4H96 A;  1DR5 A;  1RX4 A;  3FQC A;  4Q6A A;  1VDR A;  4NX6 A;  2HM9 A;  4HOG A;  1DRH A;  1DYH A;  2D5N A;  3QL3 A;  1RH3 A;  2OBC A;  1RB3 A;  3IA4 A;  2O7P A;  4IXE D;  3CSE A;  4KBN A;  4XT6 A;  3FYV X;  3QLR A;  1BZF A;  3KJS A;  4P3R A;  3NXR A;  4ELH A;  3FQZ A;  3E0B A;  1M7A A;  1PDB A;  3JWK A;  3DGA A;  5HT5 A;  1OHJ A;  3QLX A;  1PD8 A;  3SGY A;  4X5G A;  2C2S A;  1ZDR A;  1RX9 A;  3F0B X;  1DR6 A;  1J3J A;  4RGC A;  4EIZ A;  4Q67 A;  5HT4 A;  1HFR A;  3SA1 A;  1M79 A;  3QL0 A;  4LEK X;  1U70 A;  4QHV A;  3DFR A;  3SRW X;  1RX6 A;  4QLF A;  1AI9 A;  1RD7 A;  4LAG X;  4CD2 A;  3EEK A;  2AZN A;  3NXV A;  2CIG A;  3DG8 A;  2ANQ A;  4PDJ A;  5HF0 X;  3F0V X;  6DFR A;  5HQZ A;  5HQY A;  1CZ3 A;  2ITH A;  3JWM A;  4P3Q A;  4QJC A;  3NU0 A;  3SQY X;  2ANO A;  1DRA A;  3TQ9 A;  3S9U A;  3DAU A;  1RX8 A;  1DHI A;  4PTH A;  4EIG A;  1DG7 A;  1U72 A;  1J3K A;  1DR3 A;  2W3M A;  4ELB A;  1LY4 A;  3JVX A;  4G95 A;  3UM5 A;  1QZF A;  3LG4 A;  3QLZ A;  3FL8 A;  5U27 A;  5U26 A;  3FQF A;  4DDR A;  1OHK A;  3F0X X;  3K47 A;  1D1G A;  4I13 A;  4HOF A;  1DR7 A;  4FGH A;  1YHO A;  3S7A A;  5HSU A;  3F8Y A;  3HJ3 A;  4M2X A;  1DAJ A;  4KLX A;  1DDS A;  4KM0 A;  4G8Z X;  4FGG A;  4HOE A;  3JWC A;  5E8Q A;  4H98 A;  4XRB A;  3CD2 A;  1RF7 A;  4X5F A;  4PTJ A;  3CLB A;  4OR7 A;  3KJR A;  1RA8 A;  1IA4 A;  1RB2 A;  2W3A A;  3JWF A;  4XT7 A;  4M6J A;  1AOE A;  5HVB A;  5CC9 A;  4KFJ A;  4QJZ D;  1RA2 A;  3FYW X;  1DLS A;  4IXF X;  1RA1 A;  3IRN A;  1TDR A;  3IRO A;  2BLA A;  3F8Z A;  3EEM A;  3F0S X;  3IX9 A;  4PSS A;  3I3R A;  3S3V A;  5HPB A;  1DR4 A;  1MVS A;  4XEC X;  3GHV A;  1AO8 A;  3RG9 A;  2XW7 A;  4QLE A;  1DYR A;  3L3R A;  1RX7 A;  3CL9 A;  2HQP A;  4XE6 X;  1S3U A;  3QG2 A;  2GD9 A;  3DAT A;  4EJ1 A;  4M7U A;  2D0K A;  3SR5 X;  3DL5 A;  3NXT A;  3EX8 A;  4XT4 A;  3FQ0 A;  2FZJ A;  3TD8 A;  4KJK A;  4Q0D A;  1RA3 A;  1DHF A;  3HBB A;  3JW3 A;  4DPD A;  1LUD A;  1HFP A;  3NTZ A;  4KM2 A;  3NXY A;  3EIG A;  1S3V A;  3ROA A;  4H95 A;  3ZPC A;  4ELE A;  1DHJ A;  2B3Z A; 
#chains in the Genus database with same CATH homology
 1PD9 A;  3QFX A;  3VCO A;  3JW5 A;  3N0H A;  3KGY A;  1DR1 A;  1KMS A;  3FRA X;  1SEJ A;  2OIP A;  5HUI A;  2C2T A;  1RX1 A;  4ELF A;  2BLC A;  2W3W A;  3NZD A;  4M7V A;  3NZB X;  1IA3 A;  3KY8 A;  2CD2 A;  3FQV A;  5EAJ A;  3GHC A;  3FS6 A;  1J3I A;  4X5H A;  3SAI A;  2H2Q A;  3NRR A;  4NX7 A;  3D84 X;  4Q0E A;  1LY3 A;  3QLW A;  3GYF A;  2ZZA A;  4DPH A;  2BLB A;  3TQ8 A;  1S3W A;  4XT8 A;  1IA1 A;  2INQ A;  3QGT A;  1DRF A;  4TU5 X;  1DIS A;  1CD2 A;  3OCH A;  2FZH A;  4IXG X;  5JA3 A;  4QLG A;  3SH2 A;  1MVT A;  3R33 A;  5HSR A;  2QK8 A;  2JYB A;  3GI2 A;  4GH8 A;  5DXV A;  1JOL A;  3SRQ X;  3NZ6 X;  4H97 A;  3EEL A;  1S3Y A;  5DFR A;  4QI9 A;  2FZI A;  3DL6 A;  3FY9 X;  2DHF A;  4X5J A;  5ECX A;  3TQB A;  3D80 A;  5CCC A;  3NXO A;  4KD7 A;  4KL9 A;  2P4G A;  5HF2 X;  5FDA A;  4P66 A;  2L28 A;  2W9H A;  3M09 A;  5JG0 X;  1KMV A;  1VJ3 A;  1DDR A;  2W3B A;  3NZA X;  3NZ9 X;  1RX5 A;  5HI6 A;  2DRC A;  5HVE A;  1RX3 A;  3JSU A;  3OAF A;  4ELG A;  3DRC A;  4EIL A;  3UM8 A;  1DG8 A;  3TQA A;  3KFY A;  4HA7 A;  2LF1 A;  3SRU X;  4KYA A;  3EEJ A;  5ECC A;  2W9T A;  3GHW A;  8DFR A;  3JTW A;  3F0Q X;  4LAE X;  1KLK A;  3FRD X;  4M6L A;  4KY8 A;  3FRB X;  4P68 A;  2G6V A;  2W9G A;  4KEB A;  4PST A;  4I1N A;  1DR2 A;  4FHB A;  4DFR A;  2KGK A;  3K74 A;  1DYJ A;  1RE7 A;  1RX2 A;  4M6K A;  4ECK A;  1DG5 A;  3SRR X;  3SRS X;  3INV A;  3FL9 A;  3FY8 X;  3K2H A;  3NZC X;  1RA9 A;  1HFQ A;  1U71 A;  3FQO A;  3Q1H A;  1DYI A;  4DP3 A;  4OSG A;  3IRM A;  1DLR A;  1RC4 A;  4G3M A;  3ZPG A;  3SA2 A;  3F0U X;  3QLY A;  3QYO A;  3K45 A;  1JUV A;  4X5I A;  1E26 A;  3M08 A;  4PSY A;  1DRB A;  2W3V A;  1DF7 A;  1RG7 A;  4LAH X;  2HXV A;  4KJJ A;  3UM6 A;  1JOM A;  4KAK A;  3RO9 A;  3NXX A;  1BOZ A;  1M78 A;  4KNE A;  4HA9 A;  2BL9 A;  4XT5 A;  1DRE A;  7DFR A;  3QLS A;  3QYL A;  3F91 A;  1IA2 A;  3IA5 A;  1DIU A;  4KY4 A;  4KJL A;  3FRF X;  2W9S A;  3I8A X;  3FRE X;  4H96 A;  1DR5 A;  1RX4 A;  3FQC A;  4Q6A A;  1VDR A;  4NX6 A;  2HM9 A;  4HOG A;  1DRH A;  1DYH A;  2D5N A;  3QL3 A;  1RH3 A;  2OBC A;  1RB3 A;  3IA4 A;  2O7P A;  4IXE D;  3CSE A;  4KBN A;  4XT6 A;  3FYV X;  3QLR A;  1BZF A;  3KJS A;  4P3R A;  3NXR A;  4ELH A;  3FQZ A;  3E0B A;  1M7A A;  1PDB A;  3JWK A;  3DGA A;  5HT5 A;  1OHJ A;  3QLX A;  1PD8 A;  3SGY A;  4X5G A;  2C2S A;  1ZDR A;  1RX9 A;  3F0B X;  1DR6 A;  1J3J A;  4RGC A;  4EIZ A;  4Q67 A;  5HT4 A;  1HFR A;  3SA1 A;  1M79 A;  3QL0 A;  4LEK X;  1U70 A;  4QHV A;  3DFR A;  3SRW X;  1RX6 A;  4QLF A;  1AI9 A;  1RD7 A;  4LAG X;  4CD2 A;  3EEK A;  2AZN A;  3NXV A;  2CIG A;  3DG8 A;  2ANQ A;  4PDJ A;  5HF0 X;  3F0V X;  6DFR A;  5HQZ A;  5HQY A;  1CZ3 A;  2ITH A;  3JWM A;  4P3Q A;  4QJC A;  3NU0 A;  3SQY X;  2ANO A;  1DRA A;  3TQ9 A;  3S9U A;  3DAU A;  1RX8 A;  1DHI A;  4PTH A;  4EIG A;  1DG7 A;  1U72 A;  1J3K A;  1DR3 A;  2W3M A;  4ELB A;  1LY4 A;  3JVX A;  4G95 A;  3UM5 A;  1QZF A;  3LG4 A;  3QLZ A;  3FL8 A;  5U27 A;  5U26 A;  3FQF A;  4DDR A;  1OHK A;  3F0X X;  3K47 A;  1D1G A;  4I13 A;  4HOF A;  1DR7 A;  4FGH A;  1YHO A;  3S7A A;  5HSU A;  3F8Y A;  3HJ3 A;  4M2X A;  1DAJ A;  4KLX A;  1DDS A;  4KM0 A;  4G8Z X;  4FGG A;  4HOE A;  3JWC A;  5E8Q A;  4H98 A;  4XRB A;  3CD2 A;  1RF7 A;  4X5F A;  4PTJ A;  3CLB A;  4OR7 A;  3KJR A;  1RA8 A;  1IA4 A;  1RB2 A;  2W3A A;  3JWF A;  4XT7 A;  4M6J A;  1AOE A;  5HVB A;  5CC9 A;  4KFJ A;  4QJZ D;  1RA2 A;  3FYW X;  1DLS A;  4IXF X;  1RA1 A;  3IRN A;  1TDR A;  3IRO A;  2BLA A;  3F8Z A;  3EEM A;  3F0S X;  3IX9 A;  4PSS A;  3I3R A;  3S3V A;  5HPB A;  1DR4 A;  1MVS A;  4XEC X;  3GHV A;  1AO8 A;  3RG9 A;  2XW7 A;  4QLE A;  1DYR A;  3L3R A;  1RX7 A;  3CL9 A;  2HQP A;  4XE6 X;  1S3U A;  3QG2 A;  2GD9 A;  3DAT A;  4EJ1 A;  4M7U A;  2D0K A;  3SR5 X;  3DL5 A;  3NXT A;  3EX8 A;  4XT4 A;  3FQ0 A;  2FZJ A;  3TD8 A;  4KJK A;  4Q0D A;  1RA3 A;  1DHF A;  3HBB A;  3JW3 A;  4DPD A;  1LUD A;  1HFP A;  3NTZ A;  4KM2 A;  3NXY A;  3EIG A;  1S3V A;  3ROA A;  4H95 A;  3ZPC A;  4ELE A;  1DHJ A;  2B3Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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