4H95A

Candida albicans dihydrofolate reductase complexed with nadph and 6-ethyl-5-{3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine (ucp1006)
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
189
structure length
189
Chain Sequence
PNVAIIVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHASSIESSLNLVSDVERVFIIGGAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFLKFPLESWTKQPKSELQKFVGDTVLEDDIKEGDFTYNYTLWTRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species.
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Candida albicans
molecule keywords Dihydrofolate Reductase
total genus 51
structure length 189
sequence length 189
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2012-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4h95A00
1S3UA 2P4GA 5HVBA 4ELGA 1PDBA 3F0XX 4KBNA 4PTJA 4ELEA 2C2TA 1DYJA 3DAUA 3SA2A 4QLEA 1RX4A 3GHWA 4KLXA 3I8AX 3NZDA 7DFRA 2ITHA 3JWCA 3FRFX 1DR7A 3L3RA 2OBCA 4HOFA 2DRCA 4P68A 3NZAX 1QZFA 1E26A 2CD2A 2GD9A 1J3JA 4KEBA 3RO9A 3EEKA 5U26A 5HT4A 4M6KA 4XT5A 4M7UA 2B3ZA 3HBBA 4LAHX 1RX6A 3EX8A 1RB3A 3KJRA 2W9GA 3SR5X 1RB2A 5CC9A 1BZFA 1TDRA 5ECCA 1RD7A 3UM5A 1M78A 4QI9A 5HUIA 3FY8X 5CCCA 1DR3A 4M2XA 3S9UA 3NXOA 3FL9A 3SRWX 3JW5A 3SRRX 1DG8A 1DRFA 1PD9A 3QL3A 1DHIA 4DPDA 1J3IA 1RG7A 1S3WA 2H2QA 3FQZA 3FRDX 3KJSA 1AI9A 4Q67A 4PSYA 4KJLA 2FZHA 3S3VA 3IROA 3QLRA 3OCHA 3IA4A 4G8ZX 1DHJA 4PDJA 3JW3A 3GHVA 4XE6X 1RX9A 3E0BA 4QLGA 3UM8A 4M6LA 1OHKA 2BLBA 3JVXA 2ANOA 3QYLA 1DIUA 3D80A 1DYIA 1RX5A 3FQOA 4M6JA 4X5FA 3F0SX 1KMVA 3UM6A 2W9TA 2CIGA 1IA4A 5HQZA 4Q0DA 3F8YA 2BL9A 4HOGA 3JWKA 1SEJA 4ECKA 1BOZA 3FQCA 4QJZD 2G6VA 1CD2A 4QLFA 4XT8A 1MVTA 4IXGX 2D5NA 4Q0EA 3JTWA 4X5IA 5HSRA 3QGTA 5HSUA 4KM0A 5HPBA 3FL8A 1KLKA 5EAJA 1DR6A 1DHFA 3LG4A 1RA9A 2HXVA 2AZNA 1S3VA 3DL5A 4XT7A 1AO8A 3F0BX 3EEMA 1RH3A 4DDRA 1DAJA 2W9HA 1RX3A 3F91A 5HF2X 2L28A 4FGGA 3CLBA 5JG0X 2W3AA 3EELA 3NZCX 1DG5A 4X5JA 3IRMA 3I3RA 3QLSA 4ELFA 3QLYA 3IX9A 4KFJA 4H95A 1HFRA 5HF0X 1HFQA 3DGAA 6DFRA 4ELBA 1S3YA 2W3BA 4HA7A 4CD2A 4OR7A 1DF7A 1RX8A 1LY4A 3K47A 1OHJA 4KNEA 1VJ3A 4LEKX 5HT5A 4P3RA 1RA1A 4HOEA 4G3MA 1IA1A 3SGYA 1DREA 3F0QX 4P3QA 3SQYX 4M7VA 1DYHA 1KMSA 3CD2A 4DFRA 3SH2A 4LAGX 2KGKA 1U70A 4QHVA 1RA3A 3FRBX 3NZBX 3ZPGA 5HVEA 1RA2A 3QFXA 2QK8A 3HJ3A 3DFRA 4QJCA 3S7AA 4NX6A 3DG8A 1IA2A 3NXTA 1DR2A 1U72A 2D0KA 4KYAA 3F0VX 3NXVA 3GYFA 2ANQA 1JOLA 1DRBA 4OSGA 4KL9A 5U27A 1LUDA 1RC4A 3SRUX 1VDRA 1M79A 4H98A 2DHFA 3DRCA 1M7AA 2HM9A 4PSTA 2FZJA 1HFPA 3QG2A 4IXED 1D1GA 3FS6A 3JWMA 1DLRA 3FQ0A 3GHCA 5HI6A 1JOMA 1LY3A 3EIGA 3NZ9X 5HQYA 3NXYA 1DR5A 3CSEA 3IA5A 4DP3A 4H96A 3QL0A 3FYVX 5JA3A 4G95A 3VCOA 4KJKA 3FQVA 4EIZA 1DG7A 1MVSA 3M08A 3NRRA 3K45A 4KAKA 2W3WA 3FYWX 4HA9A 4XRBA 4XT4A 3NXRA 3SRSX 1DRAA 3QLWA 3SRQX 2W9SA 4DPHA 3ROAA 3OAFA 4Q6AA 3TQBA 3F8ZA 3NU0A 4LAEX 2O7PA 4PSSA 2ZZAA 5E8QA 3KFYA 3K2HA 3SA1A 1DDRA 3QLZA 4EILA 4KY8A 1RF7A 2JYBA 1YHOA 2BLCA 2BLAA 1DISA 3INVA 2INQA 3QLXA 4KJJA 3M09A 1RX1A 2XW7A 3EEJA 3NZ6X 1RA8A 1RX7A 3NXXA 5FDAA 3FY9X 3N0HA 4I13A 3IRNA 1DDSA 5DFRA 1J3KA 2W3MA 3DATA 3JWFA 3FREX 1DLSA 4X5HA 2OIPA 4KD7A 4X5GA 1DRHA 4NX7A 1PD8A 3CL9A 2W3VA 1DYRA 2HQPA 4FGHA 4FHBA 3NTZA 3FRAX 4P66A 3GI2A 1AOEA 8DFRA 1CZ3A 1RX2A 3D84X 3FQFA 3TQAA 4ELHA 4H97A 4KY4A 2C2SA 2LF1A 1DR4A 3TQ8A 3TQ9A 4KM2A 1JUVA 4I1NA 3K74A 3RG9A 3SAIA 5DXVA 3TD8A 1RE7A 3QYOA 3R33A 4XECX 3ZPCA 4TU5X 4EJ1A 5ECXA 1DR1A 2FZIA 3Q1HA 4RGCA 3DL6A 4GH8A 3JSUA 3F0UX 4XT6A 4EIGA 1ZDRA 4IXFX 1U71A 3KGYA 4PTHA 3KY8A 1IA3A
chains in the Genus database with same CATH superfamily
1S3UA 2P4GA 5HVBA 4ELGA 1PDBA 3F0XX 4KBNA 4PTJA 4ELEA 2C2TA 1DYJA 3DAUA 3SA2A 4QLEA 1RX4A 3GHWA 4KLXA 3I8AX 3NZDA 7DFRA 2ITHA 3JWCA 3FRFX 1DR7A 3L3RA 2OBCA 4HOFA 2DRCA 4P68A 3NZAX 1QZFA 1E26A 2CD2A 2GD9A 1J3JA 4KEBA 3RO9A 3EEKA 5U26A 5HT4A 4M6KA 4XT5A 4M7UA 2B3ZA 3HBBA 4LAHX 1RX6A 3EX8A 1RB3A 3KJRA 2W9GA 3SR5X 1RB2A 5CC9A 1BZFA 1TDRA 5ECCA 1RD7A 3UM5A 1M78A 4QI9A 5HUIA 3FY8X 5CCCA 1DR3A 4M2XA 3S9UA 3NXOA 3FL9A 3SRWX 3JW5A 3SRRX 1DG8A 1DRFA 1PD9A 3QL3A 1DHIA 4DPDA 1J3IA 1RG7A 1S3WA 2H2QA 3FQZA 3FRDX 3KJSA 1AI9A 4Q67A 4PSYA 4KJLA 2FZHA 3S3VA 3IROA 3QLRA 3OCHA 3IA4A 4G8ZX 1DHJA 4PDJA 3JW3A 3GHVA 4XE6X 1RX9A 3E0BA 4QLGA 3UM8A 4M6LA 1OHKA 2BLBA 3JVXA 2ANOA 3QYLA 1DIUA 3D80A 1DYIA 1RX5A 3FQOA 4M6JA 4X5FA 3F0SX 1KMVA 3UM6A 2W9TA 2CIGA 1IA4A 5HQZA 4Q0DA 3F8YA 2BL9A 4HOGA 3JWKA 1SEJA 4ECKA 1BOZA 3FQCA 4QJZD 2G6VA 1CD2A 4QLFA 4XT8A 1MVTA 4IXGX 2D5NA 4Q0EA 3JTWA 4X5IA 5HSRA 3QGTA 5HSUA 4KM0A 5HPBA 3FL8A 1KLKA 5EAJA 1DR6A 1DHFA 3LG4A 1RA9A 2HXVA 2AZNA 1S3VA 3DL5A 4XT7A 1AO8A 3F0BX 3EEMA 1RH3A 4DDRA 1DAJA 2W9HA 1RX3A 3F91A 5HF2X 2L28A 4FGGA 3CLBA 5JG0X 2W3AA 3EELA 3NZCX 1DG5A 4X5JA 3IRMA 3I3RA 3QLSA 4ELFA 3QLYA 3IX9A 4KFJA 4H95A 1HFRA 5HF0X 1HFQA 3DGAA 6DFRA 4ELBA 1S3YA 2W3BA 4HA7A 4CD2A 4OR7A 1DF7A 1RX8A 1LY4A 3K47A 1OHJA 4KNEA 1VJ3A 4LEKX 5HT5A 4P3RA 1RA1A 4HOEA 4G3MA 1IA1A 3SGYA 1DREA 3F0QX 4P3QA 3SQYX 4M7VA 1DYHA 1KMSA 3CD2A 4DFRA 3SH2A 4LAGX 2KGKA 1U70A 4QHVA 1RA3A 3FRBX 3NZBX 3ZPGA 5HVEA 1RA2A 3QFXA 2QK8A 3HJ3A 3DFRA 4QJCA 3S7AA 4NX6A 3DG8A 1IA2A 3NXTA 1DR2A 1U72A 2D0KA 4KYAA 3F0VX 3NXVA 3GYFA 2ANQA 1JOLA 1DRBA 4OSGA 4KL9A 5U27A 1LUDA 1RC4A 3SRUX 1VDRA 1M79A 4H98A 2DHFA 3DRCA 1M7AA 2HM9A 4PSTA 2FZJA 1HFPA 3QG2A 4IXED 1D1GA 3FS6A 3JWMA 1DLRA 3FQ0A 3GHCA 5HI6A 1JOMA 1LY3A 3EIGA 3NZ9X 5HQYA 3NXYA 1DR5A 3CSEA 3IA5A 4DP3A 4H96A 3QL0A 3FYVX 5JA3A 4G95A 3VCOA 4KJKA 3FQVA 4EIZA 1DG7A 1MVSA 3M08A 3NRRA 3K45A 4KAKA 2W3WA 3FYWX 4HA9A 4XRBA 4XT4A 3NXRA 3SRSX 1DRAA 3QLWA 3SRQX 2W9SA 4DPHA 3ROAA 3OAFA 4Q6AA 3TQBA 3F8ZA 3NU0A 4LAEX 2O7PA 4PSSA 2ZZAA 5E8QA 3KFYA 3K2HA 3SA1A 1DDRA 3QLZA 4EILA 4KY8A 1RF7A 2JYBA 1YHOA 2BLCA 2BLAA 1DISA 3INVA 2INQA 3QLXA 4KJJA 3M09A 1RX1A 2XW7A 3EEJA 3NZ6X 1RA8A 1RX7A 3NXXA 5FDAA 3FY9X 3N0HA 4I13A 3IRNA 1DDSA 5DFRA 1J3KA 2W3MA 3DATA 3JWFA 3FREX 1DLSA 4X5HA 2OIPA 4KD7A 4X5GA 1DRHA 4NX7A 1PD8A 3CL9A 2W3VA 1DYRA 2HQPA 4FGHA 4FHBA 3NTZA 3FRAX 4P66A 3GI2A 1AOEA 8DFRA 1CZ3A 1RX2A 3D84X 3FQFA 3TQAA 4ELHA 4H97A 4KY4A 2C2SA 2LF1A 1DR4A 3TQ8A 3TQ9A 4KM2A 1JUVA 4I1NA 3K74A 3RG9A 3SAIA 5DXVA 3TD8A 1RE7A 3QYOA 3R33A 4XECX 3ZPCA 4TU5X 4EJ1A 5ECXA 1DR1A 2FZIA 3Q1HA 4RGCA 3DL6A 4GH8A 3JSUA 3F0UX 4XT6A 4EIGA 1ZDRA 4IXFX 1U71A 3KGYA 4PTHA 3KY8A 1IA3A
chains in the Genus database with same CATH topology
1S3UA 2P4GA 5HVBA 4ELGA 1PDBA 3F0XX 4KBNA 4PTJA 4ELEA 2C2TA 1DYJA 3DAUA 3SA2A 4QLEA 1RX4A 3GHWA 4KLXA 3I8AX 3NZDA 7DFRA 2ITHA 3JWCA 3FRFX 1DR7A 3L3RA 2OBCA 4HOFA 2DRCA 4P68A 3NZAX 1QZFA 1E26A 2CD2A 2GD9A 1J3JA 4KEBA 3RO9A 3EEKA 5U26A 5HT4A 4M6KA 4XT5A 4M7UA 2B3ZA 3HBBA 4LAHX 1RX6A 3EX8A 1RB3A 3KJRA 2W9GA 3SR5X 1RB2A 5CC9A 1BZFA 1TDRA 5ECCA 1RD7A 3UM5A 1M78A 4QI9A 5HUIA 3FY8X 5CCCA 1DR3A 4M2XA 3S9UA 3NXOA 3FL9A 3SRWX 3JW5A 3SRRX 1DG8A 1DRFA 1PD9A 3QL3A 1DHIA 4DPDA 1J3IA 1RG7A 1S3WA 2H2QA 3FQZA 3FRDX 3KJSA 1AI9A 4Q67A 4PSYA 4KJLA 2FZHA 3S3VA 3IROA 3QLRA 3OCHA 3IA4A 4G8ZX 1DHJA 4PDJA 3JW3A 3GHVA 4XE6X 1RX9A 3E0BA 4QLGA 3UM8A 4M6LA 1OHKA 2BLBA 3JVXA 2ANOA 3QYLA 1DIUA 3D80A 1DYIA 1RX5A 3FQOA 4M6JA 4X5FA 3F0SX 1KMVA 3UM6A 2W9TA 2CIGA 1IA4A 5HQZA 4Q0DA 3F8YA 2BL9A 4HOGA 3JWKA 1SEJA 4ECKA 1BOZA 3FQCA 4QJZD 2G6VA 1CD2A 4QLFA 4XT8A 1MVTA 4IXGX 2D5NA 4Q0EA 3JTWA 4X5IA 5HSRA 3QGTA 5HSUA 4KM0A 5HPBA 3FL8A 1KLKA 5EAJA 1DR6A 1DHFA 3LG4A 1RA9A 2HXVA 2AZNA 1S3VA 3DL5A 4XT7A 1AO8A 3F0BX 3EEMA 1RH3A 4DDRA 1DAJA 2W9HA 1RX3A 3F91A 5HF2X 2L28A 4FGGA 3CLBA 5JG0X 2W3AA 3EELA 3NZCX 1DG5A 4X5JA 3IRMA 3I3RA 3QLSA 4ELFA 3QLYA 3IX9A 4KFJA 4H95A 1HFRA 5HF0X 1HFQA 3DGAA 6DFRA 4ELBA 1S3YA 2W3BA 4HA7A 4CD2A 4OR7A 1DF7A 1RX8A 1LY4A 3K47A 1OHJA 4KNEA 1VJ3A 4LEKX 5HT5A 4P3RA 1RA1A 4HOEA 4G3MA 1IA1A 3SGYA 1DREA 3F0QX 4P3QA 3SQYX 4M7VA 1DYHA 1KMSA 3CD2A 4DFRA 3SH2A 4LAGX 2KGKA 1U70A 4QHVA 1RA3A 3FRBX 3NZBX 3ZPGA 5HVEA 1RA2A 3QFXA 2QK8A 3HJ3A 3DFRA 4QJCA 3S7AA 4NX6A 3DG8A 1IA2A 3NXTA 1DR2A 1U72A 2D0KA 4KYAA 3F0VX 3NXVA 3GYFA 2ANQA 1JOLA 1DRBA 4OSGA 4KL9A 5U27A 1LUDA 1RC4A 3SRUX 1VDRA 1M79A 4H98A 2DHFA 3DRCA 1M7AA 2HM9A 4PSTA 2FZJA 1HFPA 3QG2A 4IXED 1D1GA 3FS6A 3JWMA 1DLRA 3FQ0A 3GHCA 5HI6A 1JOMA 1LY3A 3EIGA 3NZ9X 5HQYA 3NXYA 1DR5A 3CSEA 3IA5A 4DP3A 4H96A 3QL0A 3FYVX 5JA3A 4G95A 3VCOA 4KJKA 3FQVA 4EIZA 1DG7A 1MVSA 3M08A 3NRRA 3K45A 4KAKA 2W3WA 3FYWX 4HA9A 4XRBA 4XT4A 3NXRA 3SRSX 1DRAA 3QLWA 3SRQX 2W9SA 4DPHA 3ROAA 3OAFA 4Q6AA 3TQBA 3F8ZA 3NU0A 4LAEX 2O7PA 4PSSA 2ZZAA 5E8QA 3KFYA 3K2HA 3SA1A 1DDRA 3QLZA 4EILA 4KY8A 1RF7A 2JYBA 1YHOA 2BLCA 2BLAA 1DISA 3INVA 2INQA 3QLXA 4KJJA 3M09A 1RX1A 2XW7A 3EEJA 3NZ6X 1RA8A 1RX7A 3NXXA 5FDAA 3FY9X 3N0HA 4I13A 3IRNA 1DDSA 5DFRA 1J3KA 2W3MA 3DATA 3JWFA 3FREX 1DLSA 4X5HA 2OIPA 4KD7A 4X5GA 1DRHA 4NX7A 1PD8A 3CL9A 2W3VA 1DYRA 2HQPA 4FGHA 4FHBA 3NTZA 3FRAX 4P66A 3GI2A 1AOEA 8DFRA 1CZ3A 1RX2A 3D84X 3FQFA 3TQAA 4ELHA 4H97A 4KY4A 2C2SA 2LF1A 1DR4A 3TQ8A 3TQ9A 4KM2A 1JUVA 4I1NA 3K74A 3RG9A 3SAIA 5DXVA 3TD8A 1RE7A 3QYOA 3R33A 4XECX 3ZPCA 4TU5X 4EJ1A 5ECXA 1DR1A 2FZIA 3Q1HA 4RGCA 3DL6A 4GH8A 3JSUA 3F0UX 4XT6A 4EIGA 1ZDRA 4IXFX 1U71A 3KGYA 4PTHA 3KY8A 1IA3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S3U A;  2P4G A;  5HVB A;  4ELG A;  1PDB A;  3F0X X;  4KBN A;  4PTJ A;  4ELE A;  2C2T A;  1DYJ A;  3DAU A;  3SA2 A;  4QLE A;  1RX4 A;  3GHW A;  4KLX A;  3I8A X;  3NZD A;  7DFR A;  2ITH A;  3JWC A;  3FRF X;  1DR7 A;  3L3R A;  2OBC A;  4HOF A;  2DRC A;  4P68 A;  3NZA X;  1QZF A;  1E26 A;  2CD2 A;  2GD9 A;  1J3J A;  4KEB A;  3RO9 A;  3EEK A;  5U26 A;  5HT4 A;  4M6K A;  4XT5 A;  4M7U A;  2B3Z A;  3HBB A;  4LAH X;  1RX6 A;  3EX8 A;  1RB3 A;  3KJR A;  2W9G A;  3SR5 X;  1RB2 A;  5CC9 A;  1BZF A;  1TDR A;  5ECC A;  1RD7 A;  3UM5 A;  1M78 A;  4QI9 A;  5HUI A;  3FY8 X;  5CCC A;  1DR3 A;  4M2X A;  3S9U A;  3NXO A;  3FL9 A;  3SRW X;  3JW5 A;  3SRR X;  1DG8 A;  1DRF A;  1PD9 A;  3QL3 A;  1DHI A;  4DPD A;  1J3I A;  1RG7 A;  1S3W A;  2H2Q A;  3FQZ A;  3FRD X;  3KJS A;  1AI9 A;  4Q67 A;  4PSY A;  4KJL A;  2FZH A;  3S3V A;  3IRO A;  3QLR A;  3OCH A;  3IA4 A;  4G8Z X;  1DHJ A;  4PDJ A;  3JW3 A;  3GHV A;  4XE6 X;  1RX9 A;  3E0B A;  4QLG A;  3UM8 A;  4M6L A;  1OHK A;  2BLB A;  3JVX A;  2ANO A;  3QYL A;  1DIU A;  3D80 A;  1DYI A;  1RX5 A;  3FQO A;  4M6J A;  4X5F A;  3F0S X;  1KMV A;  3UM6 A;  2W9T A;  2CIG A;  1IA4 A;  5HQZ A;  4Q0D A;  3F8Y A;  2BL9 A;  4HOG A;  3JWK A;  1SEJ A;  4ECK A;  1BOZ A;  3FQC A;  4QJZ D;  2G6V A;  1CD2 A;  4QLF A;  4XT8 A;  1MVT A;  4IXG X;  2D5N A;  4Q0E A;  3JTW A;  4X5I A;  5HSR A;  3QGT A;  5HSU A;  4KM0 A;  5HPB A;  3FL8 A;  1KLK A;  5EAJ A;  1DR6 A;  1DHF A;  3LG4 A;  1RA9 A;  2HXV A;  2AZN A;  1S3V A;  3DL5 A;  4XT7 A;  1AO8 A;  3F0B X;  3EEM A;  1RH3 A;  4DDR A;  1DAJ A;  2W9H A;  1RX3 A;  3F91 A;  5HF2 X;  2L28 A;  4FGG A;  3CLB A;  5JG0 X;  2W3A A;  3EEL A;  3NZC X;  1DG5 A;  4X5J A;  3IRM A;  3I3R A;  3QLS A;  4ELF A;  3QLY A;  3IX9 A;  4KFJ A;  4H95 A;  1HFR A;  5HF0 X;  1HFQ A;  3DGA A;  6DFR A;  4ELB A;  1S3Y A;  2W3B A;  4HA7 A;  4CD2 A;  4OR7 A;  1DF7 A;  1RX8 A;  1LY4 A;  3K47 A;  1OHJ A;  4KNE A;  1VJ3 A;  4LEK X;  5HT5 A;  4P3R A;  1RA1 A;  4HOE A;  4G3M A;  1IA1 A;  3SGY A;  1DRE A;  3F0Q X;  4P3Q A;  3SQY X;  4M7V A;  1DYH A;  1KMS A;  3CD2 A;  4DFR A;  3SH2 A;  4LAG X;  2KGK A;  1U70 A;  4QHV A;  1RA3 A;  3FRB X;  3NZB X;  3ZPG A;  5HVE A;  1RA2 A;  3QFX A;  2QK8 A;  3HJ3 A;  3DFR A;  4QJC A;  3S7A A;  4NX6 A;  3DG8 A;  1IA2 A;  3NXT A;  1DR2 A;  1U72 A;  2D0K A;  4KYA A;  3F0V X;  3NXV A;  3GYF A;  2ANQ A;  1JOL A;  1DRB A;  4OSG A;  4KL9 A;  5U27 A;  1LUD A;  1RC4 A;  3SRU X;  1VDR A;  1M79 A;  4H98 A;  2DHF A;  3DRC A;  1M7A A;  2HM9 A;  4PST A;  2FZJ A;  1HFP A;  3QG2 A;  4IXE D;  1D1G A;  3FS6 A;  3JWM A;  1DLR A;  3FQ0 A;  3GHC A;  5HI6 A;  1JOM A;  1LY3 A;  3EIG A;  3NZ9 X;  5HQY A;  3NXY A;  1DR5 A;  3CSE A;  3IA5 A;  4DP3 A;  4H96 A;  3QL0 A;  3FYV X;  5JA3 A;  4G95 A;  3VCO A;  4KJK A;  3FQV A;  4EIZ A;  1DG7 A;  1MVS A;  3M08 A;  3NRR A;  3K45 A;  4KAK A;  2W3W A;  3FYW X;  4HA9 A;  4XRB A;  4XT4 A;  3NXR A;  3SRS X;  1DRA A;  3QLW A;  3SRQ X;  2W9S A;  4DPH A;  3ROA A;  3OAF A;  4Q6A A;  3TQB A;  3F8Z A;  3NU0 A;  4LAE X;  2O7P A;  4PSS A;  2ZZA A;  5E8Q A;  3KFY A;  3K2H A;  3SA1 A;  1DDR A;  3QLZ A;  4EIL A;  4KY8 A;  1RF7 A;  2JYB A;  1YHO A;  2BLC A;  2BLA A;  1DIS A;  3INV A;  2INQ A;  3QLX A;  4KJJ A;  3M09 A;  1RX1 A;  2XW7 A;  3EEJ A;  3NZ6 X;  1RA8 A;  1RX7 A;  3NXX A;  5FDA A;  3FY9 X;  3N0H A;  4I13 A;  3IRN A;  1DDS A;  5DFR A;  1J3K A;  2W3M A;  3DAT A;  3JWF A;  3FRE X;  1DLS A;  4X5H A;  2OIP A;  4KD7 A;  4X5G A;  1DRH A;  4NX7 A;  1PD8 A;  3CL9 A;  2W3V A;  1DYR A;  2HQP A;  4FGH A;  4FHB A;  3NTZ A;  3FRA X;  4P66 A;  3GI2 A;  1AOE A;  8DFR A;  1CZ3 A;  1RX2 A;  3D84 X;  3FQF A;  3TQA A;  4ELH A;  4H97 A;  4KY4 A;  2C2S A;  2LF1 A;  1DR4 A;  3TQ8 A;  3TQ9 A;  4KM2 A;  1JUV A;  4I1N A;  3K74 A;  3RG9 A;  3SAI A;  5DXV A;  3TD8 A;  1RE7 A;  3QYO A;  3R33 A;  4XEC X;  3ZPC A;  4TU5 X;  4EJ1 A;  5ECX A;  1DR1 A;  2FZI A;  3Q1H A;  4RGC A;  3DL6 A;  4GH8 A;  3JSU A;  3F0U X;  4XT6 A;  4EIG A;  1ZDR A;  4IXF X;  1U71 A;  3KGY A;  4PTH A;  3KY8 A;  1IA3 A; 
#chains in the Genus database with same CATH topology
 1S3U A;  2P4G A;  5HVB A;  4ELG A;  1PDB A;  3F0X X;  4KBN A;  4PTJ A;  4ELE A;  2C2T A;  1DYJ A;  3DAU A;  3SA2 A;  4QLE A;  1RX4 A;  3GHW A;  4KLX A;  3I8A X;  3NZD A;  7DFR A;  2ITH A;  3JWC A;  3FRF X;  1DR7 A;  3L3R A;  2OBC A;  4HOF A;  2DRC A;  4P68 A;  3NZA X;  1QZF A;  1E26 A;  2CD2 A;  2GD9 A;  1J3J A;  4KEB A;  3RO9 A;  3EEK A;  5U26 A;  5HT4 A;  4M6K A;  4XT5 A;  4M7U A;  2B3Z A;  3HBB A;  4LAH X;  1RX6 A;  3EX8 A;  1RB3 A;  3KJR A;  2W9G A;  3SR5 X;  1RB2 A;  5CC9 A;  1BZF A;  1TDR A;  5ECC A;  1RD7 A;  3UM5 A;  1M78 A;  4QI9 A;  5HUI A;  3FY8 X;  5CCC A;  1DR3 A;  4M2X A;  3S9U A;  3NXO A;  3FL9 A;  3SRW X;  3JW5 A;  3SRR X;  1DG8 A;  1DRF A;  1PD9 A;  3QL3 A;  1DHI A;  4DPD A;  1J3I A;  1RG7 A;  1S3W A;  2H2Q A;  3FQZ A;  3FRD X;  3KJS A;  1AI9 A;  4Q67 A;  4PSY A;  4KJL A;  2FZH A;  3S3V A;  3IRO A;  3QLR A;  3OCH A;  3IA4 A;  4G8Z X;  1DHJ A;  4PDJ A;  3JW3 A;  3GHV A;  4XE6 X;  1RX9 A;  3E0B A;  4QLG A;  3UM8 A;  4M6L A;  1OHK A;  2BLB A;  3JVX A;  2ANO A;  3QYL A;  1DIU A;  3D80 A;  1DYI A;  1RX5 A;  3FQO A;  4M6J A;  4X5F A;  3F0S X;  1KMV A;  3UM6 A;  2W9T A;  2CIG A;  1IA4 A;  5HQZ A;  4Q0D A;  3F8Y A;  2BL9 A;  4HOG A;  3JWK A;  1SEJ A;  4ECK A;  1BOZ A;  3FQC A;  4QJZ D;  2G6V A;  1CD2 A;  4QLF A;  4XT8 A;  1MVT A;  4IXG X;  2D5N A;  4Q0E A;  3JTW A;  4X5I A;  5HSR A;  3QGT A;  5HSU A;  4KM0 A;  5HPB A;  3FL8 A;  1KLK A;  5EAJ A;  1DR6 A;  1DHF A;  3LG4 A;  1RA9 A;  2HXV A;  2AZN A;  1S3V A;  3DL5 A;  4XT7 A;  1AO8 A;  3F0B X;  3EEM A;  1RH3 A;  4DDR A;  1DAJ A;  2W9H A;  1RX3 A;  3F91 A;  5HF2 X;  2L28 A;  4FGG A;  3CLB A;  5JG0 X;  2W3A A;  3EEL A;  3NZC X;  1DG5 A;  4X5J A;  3IRM A;  3I3R A;  3QLS A;  4ELF A;  3QLY A;  3IX9 A;  4KFJ A;  4H95 A;  1HFR A;  5HF0 X;  1HFQ A;  3DGA A;  6DFR A;  4ELB A;  1S3Y A;  2W3B A;  4HA7 A;  4CD2 A;  4OR7 A;  1DF7 A;  1RX8 A;  1LY4 A;  3K47 A;  1OHJ A;  4KNE A;  1VJ3 A;  4LEK X;  5HT5 A;  4P3R A;  1RA1 A;  4HOE A;  4G3M A;  1IA1 A;  3SGY A;  1DRE A;  3F0Q X;  4P3Q A;  3SQY X;  4M7V A;  1DYH A;  1KMS A;  3CD2 A;  4DFR A;  3SH2 A;  4LAG X;  2KGK A;  1U70 A;  4QHV A;  1RA3 A;  3FRB X;  3NZB X;  3ZPG A;  5HVE A;  1RA2 A;  3QFX A;  2QK8 A;  3HJ3 A;  3DFR A;  4QJC A;  3S7A A;  4NX6 A;  3DG8 A;  1IA2 A;  3NXT A;  1DR2 A;  1U72 A;  2D0K A;  4KYA A;  3F0V X;  3NXV A;  3GYF A;  2ANQ A;  1JOL A;  1DRB A;  4OSG A;  4KL9 A;  5U27 A;  1LUD A;  1RC4 A;  3SRU X;  1VDR A;  1M79 A;  4H98 A;  2DHF A;  3DRC A;  1M7A A;  2HM9 A;  4PST A;  2FZJ A;  1HFP A;  3QG2 A;  4IXE D;  1D1G A;  3FS6 A;  3JWM A;  1DLR A;  3FQ0 A;  3GHC A;  5HI6 A;  1JOM A;  1LY3 A;  3EIG A;  3NZ9 X;  5HQY A;  3NXY A;  1DR5 A;  3CSE A;  3IA5 A;  4DP3 A;  4H96 A;  3QL0 A;  3FYV X;  5JA3 A;  4G95 A;  3VCO A;  4KJK A;  3FQV A;  4EIZ A;  1DG7 A;  1MVS A;  3M08 A;  3NRR A;  3K45 A;  4KAK A;  2W3W A;  3FYW X;  4HA9 A;  4XRB A;  4XT4 A;  3NXR A;  3SRS X;  1DRA A;  3QLW A;  3SRQ X;  2W9S A;  4DPH A;  3ROA A;  3OAF A;  4Q6A A;  3TQB A;  3F8Z A;  3NU0 A;  4LAE X;  2O7P A;  4PSS A;  2ZZA A;  5E8Q A;  3KFY A;  3K2H A;  3SA1 A;  1DDR A;  3QLZ A;  4EIL A;  4KY8 A;  1RF7 A;  2JYB A;  1YHO A;  2BLC A;  2BLA A;  1DIS A;  3INV A;  2INQ A;  3QLX A;  4KJJ A;  3M09 A;  1RX1 A;  2XW7 A;  3EEJ A;  3NZ6 X;  1RA8 A;  1RX7 A;  3NXX A;  5FDA A;  3FY9 X;  3N0H A;  4I13 A;  3IRN A;  1DDS A;  5DFR A;  1J3K A;  2W3M A;  3DAT A;  3JWF A;  3FRE X;  1DLS A;  4X5H A;  2OIP A;  4KD7 A;  4X5G A;  1DRH A;  4NX7 A;  1PD8 A;  3CL9 A;  2W3V A;  1DYR A;  2HQP A;  4FGH A;  4FHB A;  3NTZ A;  3FRA X;  4P66 A;  3GI2 A;  1AOE A;  8DFR A;  1CZ3 A;  1RX2 A;  3D84 X;  3FQF A;  3TQA A;  4ELH A;  4H97 A;  4KY4 A;  2C2S A;  2LF1 A;  1DR4 A;  3TQ8 A;  3TQ9 A;  4KM2 A;  1JUV A;  4I1N A;  3K74 A;  3RG9 A;  3SAI A;  5DXV A;  3TD8 A;  1RE7 A;  3QYO A;  3R33 A;  4XEC X;  3ZPC A;  4TU5 X;  4EJ1 A;  5ECX A;  1DR1 A;  2FZI A;  3Q1H A;  4RGC A;  3DL6 A;  4GH8 A;  3JSU A;  3F0U X;  4XT6 A;  4EIG A;  1ZDR A;  4IXF X;  1U71 A;  3KGY A;  4PTH A;  3KY8 A;  1IA3 A; 
#chains in the Genus database with same CATH homology
 1S3U A;  2P4G A;  5HVB A;  4ELG A;  1PDB A;  3F0X X;  4KBN A;  4PTJ A;  4ELE A;  2C2T A;  1DYJ A;  3DAU A;  3SA2 A;  4QLE A;  1RX4 A;  3GHW A;  4KLX A;  3I8A X;  3NZD A;  7DFR A;  2ITH A;  3JWC A;  3FRF X;  1DR7 A;  3L3R A;  2OBC A;  4HOF A;  2DRC A;  4P68 A;  3NZA X;  1QZF A;  1E26 A;  2CD2 A;  2GD9 A;  1J3J A;  4KEB A;  3RO9 A;  3EEK A;  5U26 A;  5HT4 A;  4M6K A;  4XT5 A;  4M7U A;  2B3Z A;  3HBB A;  4LAH X;  1RX6 A;  3EX8 A;  1RB3 A;  3KJR A;  2W9G A;  3SR5 X;  1RB2 A;  5CC9 A;  1BZF A;  1TDR A;  5ECC A;  1RD7 A;  3UM5 A;  1M78 A;  4QI9 A;  5HUI A;  3FY8 X;  5CCC A;  1DR3 A;  4M2X A;  3S9U A;  3NXO A;  3FL9 A;  3SRW X;  3JW5 A;  3SRR X;  1DG8 A;  1DRF A;  1PD9 A;  3QL3 A;  1DHI A;  4DPD A;  1J3I A;  1RG7 A;  1S3W A;  2H2Q A;  3FQZ A;  3FRD X;  3KJS A;  1AI9 A;  4Q67 A;  4PSY A;  4KJL A;  2FZH A;  3S3V A;  3IRO A;  3QLR A;  3OCH A;  3IA4 A;  4G8Z X;  1DHJ A;  4PDJ A;  3JW3 A;  3GHV A;  4XE6 X;  1RX9 A;  3E0B A;  4QLG A;  3UM8 A;  4M6L A;  1OHK A;  2BLB A;  3JVX A;  2ANO A;  3QYL A;  1DIU A;  3D80 A;  1DYI A;  1RX5 A;  3FQO A;  4M6J A;  4X5F A;  3F0S X;  1KMV A;  3UM6 A;  2W9T A;  2CIG A;  1IA4 A;  5HQZ A;  4Q0D A;  3F8Y A;  2BL9 A;  4HOG A;  3JWK A;  1SEJ A;  4ECK A;  1BOZ A;  3FQC A;  4QJZ D;  2G6V A;  1CD2 A;  4QLF A;  4XT8 A;  1MVT A;  4IXG X;  2D5N A;  4Q0E A;  3JTW A;  4X5I A;  5HSR A;  3QGT A;  5HSU A;  4KM0 A;  5HPB A;  3FL8 A;  1KLK A;  5EAJ A;  1DR6 A;  1DHF A;  3LG4 A;  1RA9 A;  2HXV A;  2AZN A;  1S3V A;  3DL5 A;  4XT7 A;  1AO8 A;  3F0B X;  3EEM A;  1RH3 A;  4DDR A;  1DAJ A;  2W9H A;  1RX3 A;  3F91 A;  5HF2 X;  2L28 A;  4FGG A;  3CLB A;  5JG0 X;  2W3A A;  3EEL A;  3NZC X;  1DG5 A;  4X5J A;  3IRM A;  3I3R A;  3QLS A;  4ELF A;  3QLY A;  3IX9 A;  4KFJ A;  4H95 A;  1HFR A;  5HF0 X;  1HFQ A;  3DGA A;  6DFR A;  4ELB A;  1S3Y A;  2W3B A;  4HA7 A;  4CD2 A;  4OR7 A;  1DF7 A;  1RX8 A;  1LY4 A;  3K47 A;  1OHJ A;  4KNE A;  1VJ3 A;  4LEK X;  5HT5 A;  4P3R A;  1RA1 A;  4HOE A;  4G3M A;  1IA1 A;  3SGY A;  1DRE A;  3F0Q X;  4P3Q A;  3SQY X;  4M7V A;  1DYH A;  1KMS A;  3CD2 A;  4DFR A;  3SH2 A;  4LAG X;  2KGK A;  1U70 A;  4QHV A;  1RA3 A;  3FRB X;  3NZB X;  3ZPG A;  5HVE A;  1RA2 A;  3QFX A;  2QK8 A;  3HJ3 A;  3DFR A;  4QJC A;  3S7A A;  4NX6 A;  3DG8 A;  1IA2 A;  3NXT A;  1DR2 A;  1U72 A;  2D0K A;  4KYA A;  3F0V X;  3NXV A;  3GYF A;  2ANQ A;  1JOL A;  1DRB A;  4OSG A;  4KL9 A;  5U27 A;  1LUD A;  1RC4 A;  3SRU X;  1VDR A;  1M79 A;  4H98 A;  2DHF A;  3DRC A;  1M7A A;  2HM9 A;  4PST A;  2FZJ A;  1HFP A;  3QG2 A;  4IXE D;  1D1G A;  3FS6 A;  3JWM A;  1DLR A;  3FQ0 A;  3GHC A;  5HI6 A;  1JOM A;  1LY3 A;  3EIG A;  3NZ9 X;  5HQY A;  3NXY A;  1DR5 A;  3CSE A;  3IA5 A;  4DP3 A;  4H96 A;  3QL0 A;  3FYV X;  5JA3 A;  4G95 A;  3VCO A;  4KJK A;  3FQV A;  4EIZ A;  1DG7 A;  1MVS A;  3M08 A;  3NRR A;  3K45 A;  4KAK A;  2W3W A;  3FYW X;  4HA9 A;  4XRB A;  4XT4 A;  3NXR A;  3SRS X;  1DRA A;  3QLW A;  3SRQ X;  2W9S A;  4DPH A;  3ROA A;  3OAF A;  4Q6A A;  3TQB A;  3F8Z A;  3NU0 A;  4LAE X;  2O7P A;  4PSS A;  2ZZA A;  5E8Q A;  3KFY A;  3K2H A;  3SA1 A;  1DDR A;  3QLZ A;  4EIL A;  4KY8 A;  1RF7 A;  2JYB A;  1YHO A;  2BLC A;  2BLA A;  1DIS A;  3INV A;  2INQ A;  3QLX A;  4KJJ A;  3M09 A;  1RX1 A;  2XW7 A;  3EEJ A;  3NZ6 X;  1RA8 A;  1RX7 A;  3NXX A;  5FDA A;  3FY9 X;  3N0H A;  4I13 A;  3IRN A;  1DDS A;  5DFR A;  1J3K A;  2W3M A;  3DAT A;  3JWF A;  3FRE X;  1DLS A;  4X5H A;  2OIP A;  4KD7 A;  4X5G A;  1DRH A;  4NX7 A;  1PD8 A;  3CL9 A;  2W3V A;  1DYR A;  2HQP A;  4FGH A;  4FHB A;  3NTZ A;  3FRA X;  4P66 A;  3GI2 A;  1AOE A;  8DFR A;  1CZ3 A;  1RX2 A;  3D84 X;  3FQF A;  3TQA A;  4ELH A;  4H97 A;  4KY4 A;  2C2S A;  2LF1 A;  1DR4 A;  3TQ8 A;  3TQ9 A;  4KM2 A;  1JUV A;  4I1N A;  3K74 A;  3RG9 A;  3SAI A;  5DXV A;  3TD8 A;  1RE7 A;  3QYO A;  3R33 A;  4XEC X;  3ZPC A;  4TU5 X;  4EJ1 A;  5ECX A;  1DR1 A;  2FZI A;  3Q1H A;  4RGC A;  3DL6 A;  4GH8 A;  3JSU A;  3F0U X;  4XT6 A;  4EIG A;  1ZDR A;  4IXF X;  1U71 A;  3KGY A;  4PTH A;  3KY8 A;  1IA3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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