4H97A

Candida albicans dihydrofolate reductase complexed with nadph and 5-{3-[3-methoxy-5-(4-methylphenyl)phenyl]but-1-yn-1-yl}-6-methylpyrimidine-2,4-diamine (ucp111d4m)
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
190
structure length
190
Chain Sequence
KPNVAIIVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRPLPDRLNIILSRSYENEIIDDNIIHASSIESSLNLVSDVERVFIIGGAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFLKFPLESWTKQPKSELQKFVGDTVLEDDIKEGDFTYNYTLWTRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural analysis of the active sites of dihydrofolate reductase from two species of Candida uncovers ligand-induced conformational changes shared among species.
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Candida albicans
molecule keywords Dihydrofolate Reductase
total genus 54
structure length 190
sequence length 190
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2012-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4h97A00
4PSSA 1J3IA 4QLFA 3GI2A 4M7UA 3JW3A 1OHKA 2W3VA 4Q67A 3TQ8A 1RE7A 3TQ9A 4QI9A 3OCHA 4HOEA 4KM0A 3S7AA 1U72A 3NRRA 1VJ3A 5HQYA 3SRSX 1AO8A 2DRCA 4XE6X 5HVBA 5ECXA 3QLSA 3F0UX 3IX9A 2GD9A 1RG7A 1U70A 4X5GA 1KMSA 4LAGX 1RX5A 3F91A 1DG7A 1DHIA 4XT4A 3JWFA 3DFRA 3JTWA 3DATA 1IA2A 3FRAX 5HVEA 4XT8A 1RB3A 4FGHA 1KMVA 1DR5A 4Q0EA 1DLSA 5U26A 3QLYA 1BZFA 3SH2A 1HFPA 1AOEA 3SAIA 1RX9A 4PSTA 5CC9A 3FRBX 4KJKA 5E8QA 3JWMA 5HQZA 3NZBX 2H2QA 4H96A 3VCOA 1RA2A 2FZJA 3LG4A 1BOZA 2W9HA 3FY9X 3SA1A 5HT5A 3I8AX 1DDRA 2W3BA 2QK8A 4XT6A 1RH3A 4G8ZX 3FRFX 4HOGA 1ZDRA 1HFRA 4PDJA 4LEKX 2OIPA 2W9SA 4RGCA 3QLZA 3EEMA 3INVA 3FQZA 4HOFA 2AZNA 3EEJA 4ELFA 1RA1A 4Q6AA 3NXVA 2INQA 3F0SX 1M78A 1RX6A 3UM5A 1DR6A 3JWCA 3JWKA 3QYLA 1DYIA 2HXVA 4PTJA 3ROAA 5HSUA 4EIZA 3D80A 1DR3A 4LAHX 3JVXA 3IRNA 3HJ3A 1D1GA 3NZ9X 2O7PA 3FY8X 4XRBA 3UM6A 3NXYA 1SEJA 4P66A 3N0HA 4M7VA 3TQBA 4KNEA 3DG8A 1IA3A 1CZ3A 3Q1HA 4EILA 4Q0DA 4H98A 3QGTA 3SRRX 1DHJA 1RF7A 3FREX 4XECX 3NXOA 3FL9A 4IXFX 4HA7A 2ANOA 1QZFA 1DR7A 4ECKA 2DHFA 1RA8A 4M6KA 3S9UA 4KY4A 3NXTA 5JG0X 1JOMA 3FL8A 3CD2A 3K2HA 2BL9A 3SR5X 3NZCX 5EAJA 2W9TA 4FGGA 4LAEX 1KLKA 1DDSA 1DHFA 1S3VA 2C2SA 3NZAX 1IA1A 1S3YA 1DAJA 4IXED 4DP3A 3SRUX 3EELA 4NX7A 3QLXA 3D84X 3F0VX 4KBNA 1DR2A 4M6JA 1M79A 5DFRA 3F0BX 4KFJA 2L28A 3NXRA 1DRFA 4FHBA 3K74A 1E26A 3FYVX 2LF1A 1PD8A 3KGYA 4ELEA 3QYOA 4G3MA 4I1NA 4HA9A 3IRMA 5HT4A 2FZHA 4P3RA 3KJRA 3EIGA 2KGKA 3UM8A 3HBBA 3QFXA 4OR7A 3JSUA 3FQCA 4CD2A 3FQ0A 4XT7A 1OHJA 3ZPGA 4KY8A 3GHCA 1RD7A 1DG8A 1DYRA 2P4GA 5CCCA 4H97A 1U71A 3EX8A 3NU0A 1VDRA 3SA2A 3NZDA 4KAKA 4PSYA 1DISA 2G6VA 1DF7A 4TU5X 4EJ1A 4H95A 7DFRA 1RX1A 2BLAA 2JYBA 4G95A 5HF2X 4PTHA 4IXGX 1DRHA 1DIUA 1IA4A 3DRCA 3M09A 2B3ZA 2BLBA 3FQOA 1S3UA 6DFRA 1PD9A 1AI9A 4GH8A 1DYHA 1LY4A 3EEKA 4KD7A 3CL9A 1J3JA 1RX3A 2CD2A 4M2XA 4XT5A 3QLRA 1MVTA 1RX4A 4KM2A 4ELGA 2ITHA 4KJJA 1RA9A 4KYAA 5HI6A 2XW7A 1RX7A 2D0KA 4KL9A 2W3MA 1S3WA 3NXXA 4KEBA 5ECCA 3DL6A 4DPDA 3RO9A 3IA5A 4QJZD 4DFRA 1DR4A 3K47A 4X5JA 4QLGA 3F0QX 3SQYX 3GHWA 3GYFA 2HQPA 5HF0X 1DRAA 2BLCA 3SRQX 3KFYA 4ELHA 8DFRA 4QLEA 3TD8A 1PDBA 3FS6A 2CIGA 1J3KA 3TQAA 5DXVA 5HPBA 3RG9A 4M6LA 3DGAA 3FYWX 3SGYA 4P68A 4DPHA 4QHVA 4X5FA 4EIGA 1RX8A 3F8ZA 4X5IA 5HSRA 3F8YA 5FDAA 3DL5A 1RA3A 2W9GA 3SRWX 1DR1A 4DDRA 5JA3A 3DAUA 1RC4A 3FQFA 5U27A 1LUDA 2OBCA 2W3AA 3CLBA 3NZ6X 3R33A 3IROA 1TDRA 1LY3A 3QLWA 3FRDX 4NX6A 3KY8A 2D5NA 2ANQA 3KJSA 2ZZAA 3M08A 1JUVA 4X5HA 4KLXA 1YHOA 1HFQA 3I3RA 3K45A 1DYJA 1RB2A 3IA4A 3CSEA 3S3VA 3GHVA 4I13A 4KJLA 2C2TA 2HM9A 3NTZA 4OSGA 3OAFA 2W3WA 4QJCA 1DLRA 1DG5A 5HUIA 3E0BA 1RX2A 1JOLA 1M7AA 1MVSA 3QL0A 3JW5A 3ZPCA 1DRBA 4P3QA 3FQVA 2FZIA 1DREA 4ELBA 3QG2A 3L3RA 1CD2A 3F0XX 3QL3A
chains in the Genus database with same CATH superfamily
4PSSA 1J3IA 4QLFA 3GI2A 4M7UA 3JW3A 1OHKA 2W3VA 4Q67A 3TQ8A 1RE7A 3TQ9A 4QI9A 3OCHA 4HOEA 4KM0A 3S7AA 1U72A 3NRRA 1VJ3A 5HQYA 3SRSX 1AO8A 2DRCA 4XE6X 5HVBA 5ECXA 3QLSA 3F0UX 3IX9A 2GD9A 1RG7A 1U70A 4X5GA 1KMSA 4LAGX 1RX5A 3F91A 1DG7A 1DHIA 4XT4A 3JWFA 3DFRA 3JTWA 3DATA 1IA2A 3FRAX 5HVEA 4XT8A 1RB3A 4FGHA 1KMVA 1DR5A 4Q0EA 1DLSA 5U26A 3QLYA 1BZFA 3SH2A 1HFPA 1AOEA 3SAIA 1RX9A 4PSTA 5CC9A 3FRBX 4KJKA 5E8QA 3JWMA 5HQZA 3NZBX 2H2QA 4H96A 3VCOA 1RA2A 2FZJA 3LG4A 1BOZA 2W9HA 3FY9X 3SA1A 5HT5A 3I8AX 1DDRA 2W3BA 2QK8A 4XT6A 1RH3A 4G8ZX 3FRFX 4HOGA 1ZDRA 1HFRA 4PDJA 4LEKX 2OIPA 2W9SA 4RGCA 3QLZA 3EEMA 3INVA 3FQZA 4HOFA 2AZNA 3EEJA 4ELFA 1RA1A 4Q6AA 3NXVA 2INQA 3F0SX 1M78A 1RX6A 3UM5A 1DR6A 3JWCA 3JWKA 3QYLA 1DYIA 2HXVA 4PTJA 3ROAA 5HSUA 4EIZA 3D80A 1DR3A 4LAHX 3JVXA 3IRNA 3HJ3A 1D1GA 3NZ9X 2O7PA 3FY8X 4XRBA 3UM6A 3NXYA 1SEJA 4P66A 3N0HA 4M7VA 3TQBA 4KNEA 3DG8A 1IA3A 1CZ3A 3Q1HA 4EILA 4Q0DA 4H98A 3QGTA 3SRRX 1DHJA 1RF7A 3FREX 4XECX 3NXOA 3FL9A 4IXFX 4HA7A 2ANOA 1QZFA 1DR7A 4ECKA 2DHFA 1RA8A 4M6KA 3S9UA 4KY4A 3NXTA 5JG0X 1JOMA 3FL8A 3CD2A 3K2HA 2BL9A 3SR5X 3NZCX 5EAJA 2W9TA 4FGGA 4LAEX 1KLKA 1DDSA 1DHFA 1S3VA 2C2SA 3NZAX 1IA1A 1S3YA 1DAJA 4IXED 4DP3A 3SRUX 3EELA 4NX7A 3QLXA 3D84X 3F0VX 4KBNA 1DR2A 4M6JA 1M79A 5DFRA 3F0BX 4KFJA 2L28A 3NXRA 1DRFA 4FHBA 3K74A 1E26A 3FYVX 2LF1A 1PD8A 3KGYA 4ELEA 3QYOA 4G3MA 4I1NA 4HA9A 3IRMA 5HT4A 2FZHA 4P3RA 3KJRA 3EIGA 2KGKA 3UM8A 3HBBA 3QFXA 4OR7A 3JSUA 3FQCA 4CD2A 3FQ0A 4XT7A 1OHJA 3ZPGA 4KY8A 3GHCA 1RD7A 1DG8A 1DYRA 2P4GA 5CCCA 4H97A 1U71A 3EX8A 3NU0A 1VDRA 3SA2A 3NZDA 4KAKA 4PSYA 1DISA 2G6VA 1DF7A 4TU5X 4EJ1A 4H95A 7DFRA 1RX1A 2BLAA 2JYBA 4G95A 5HF2X 4PTHA 4IXGX 1DRHA 1DIUA 1IA4A 3DRCA 3M09A 2B3ZA 2BLBA 3FQOA 1S3UA 6DFRA 1PD9A 1AI9A 4GH8A 1DYHA 1LY4A 3EEKA 4KD7A 3CL9A 1J3JA 1RX3A 2CD2A 4M2XA 4XT5A 3QLRA 1MVTA 1RX4A 4KM2A 4ELGA 2ITHA 4KJJA 1RA9A 4KYAA 5HI6A 2XW7A 1RX7A 2D0KA 4KL9A 2W3MA 1S3WA 3NXXA 4KEBA 5ECCA 3DL6A 4DPDA 3RO9A 3IA5A 4QJZD 4DFRA 1DR4A 3K47A 4X5JA 4QLGA 3F0QX 3SQYX 3GHWA 3GYFA 2HQPA 5HF0X 1DRAA 2BLCA 3SRQX 3KFYA 4ELHA 8DFRA 4QLEA 3TD8A 1PDBA 3FS6A 2CIGA 1J3KA 3TQAA 5DXVA 5HPBA 3RG9A 4M6LA 3DGAA 3FYWX 3SGYA 4P68A 4DPHA 4QHVA 4X5FA 4EIGA 1RX8A 3F8ZA 4X5IA 5HSRA 3F8YA 5FDAA 3DL5A 1RA3A 2W9GA 3SRWX 1DR1A 4DDRA 5JA3A 3DAUA 1RC4A 3FQFA 5U27A 1LUDA 2OBCA 2W3AA 3CLBA 3NZ6X 3R33A 3IROA 1TDRA 1LY3A 3QLWA 3FRDX 4NX6A 3KY8A 2D5NA 2ANQA 3KJSA 2ZZAA 3M08A 1JUVA 4X5HA 4KLXA 1YHOA 1HFQA 3I3RA 3K45A 1DYJA 1RB2A 3IA4A 3CSEA 3S3VA 3GHVA 4I13A 4KJLA 2C2TA 2HM9A 3NTZA 4OSGA 3OAFA 2W3WA 4QJCA 1DLRA 1DG5A 5HUIA 3E0BA 1RX2A 1JOLA 1M7AA 1MVSA 3QL0A 3JW5A 3ZPCA 1DRBA 4P3QA 3FQVA 2FZIA 1DREA 4ELBA 3QG2A 3L3RA 1CD2A 3F0XX 3QL3A
chains in the Genus database with same CATH topology
4PSSA 1J3IA 4QLFA 3GI2A 4M7UA 3JW3A 1OHKA 2W3VA 4Q67A 3TQ8A 1RE7A 3TQ9A 4QI9A 3OCHA 4HOEA 4KM0A 3S7AA 1U72A 3NRRA 1VJ3A 5HQYA 3SRSX 1AO8A 2DRCA 4XE6X 5HVBA 5ECXA 3QLSA 3F0UX 3IX9A 2GD9A 1RG7A 1U70A 4X5GA 1KMSA 4LAGX 1RX5A 3F91A 1DG7A 1DHIA 4XT4A 3JWFA 3DFRA 3JTWA 3DATA 1IA2A 3FRAX 5HVEA 4XT8A 1RB3A 4FGHA 1KMVA 1DR5A 4Q0EA 1DLSA 5U26A 3QLYA 1BZFA 3SH2A 1HFPA 1AOEA 3SAIA 1RX9A 4PSTA 5CC9A 3FRBX 4KJKA 5E8QA 3JWMA 5HQZA 3NZBX 2H2QA 4H96A 3VCOA 1RA2A 2FZJA 3LG4A 1BOZA 2W9HA 3FY9X 3SA1A 5HT5A 3I8AX 1DDRA 2W3BA 2QK8A 4XT6A 1RH3A 4G8ZX 3FRFX 4HOGA 1ZDRA 1HFRA 4PDJA 4LEKX 2OIPA 2W9SA 4RGCA 3QLZA 3EEMA 3INVA 3FQZA 4HOFA 2AZNA 3EEJA 4ELFA 1RA1A 4Q6AA 3NXVA 2INQA 3F0SX 1M78A 1RX6A 3UM5A 1DR6A 3JWCA 3JWKA 3QYLA 1DYIA 2HXVA 4PTJA 3ROAA 5HSUA 4EIZA 3D80A 1DR3A 4LAHX 3JVXA 3IRNA 3HJ3A 1D1GA 3NZ9X 2O7PA 3FY8X 4XRBA 3UM6A 3NXYA 1SEJA 4P66A 3N0HA 4M7VA 3TQBA 4KNEA 3DG8A 1IA3A 1CZ3A 3Q1HA 4EILA 4Q0DA 4H98A 3QGTA 3SRRX 1DHJA 1RF7A 3FREX 4XECX 3NXOA 3FL9A 4IXFX 4HA7A 2ANOA 1QZFA 1DR7A 4ECKA 2DHFA 1RA8A 4M6KA 3S9UA 4KY4A 3NXTA 5JG0X 1JOMA 3FL8A 3CD2A 3K2HA 2BL9A 3SR5X 3NZCX 5EAJA 2W9TA 4FGGA 4LAEX 1KLKA 1DDSA 1DHFA 1S3VA 2C2SA 3NZAX 1IA1A 1S3YA 1DAJA 4IXED 4DP3A 3SRUX 3EELA 4NX7A 3QLXA 3D84X 3F0VX 4KBNA 1DR2A 4M6JA 1M79A 5DFRA 3F0BX 4KFJA 2L28A 3NXRA 1DRFA 4FHBA 3K74A 1E26A 3FYVX 2LF1A 1PD8A 3KGYA 4ELEA 3QYOA 4G3MA 4I1NA 4HA9A 3IRMA 5HT4A 2FZHA 4P3RA 3KJRA 3EIGA 2KGKA 3UM8A 3HBBA 3QFXA 4OR7A 3JSUA 3FQCA 4CD2A 3FQ0A 4XT7A 1OHJA 3ZPGA 4KY8A 3GHCA 1RD7A 1DG8A 1DYRA 2P4GA 5CCCA 4H97A 1U71A 3EX8A 3NU0A 1VDRA 3SA2A 3NZDA 4KAKA 4PSYA 1DISA 2G6VA 1DF7A 4TU5X 4EJ1A 4H95A 7DFRA 1RX1A 2BLAA 2JYBA 4G95A 5HF2X 4PTHA 4IXGX 1DRHA 1DIUA 1IA4A 3DRCA 3M09A 2B3ZA 2BLBA 3FQOA 1S3UA 6DFRA 1PD9A 1AI9A 4GH8A 1DYHA 1LY4A 3EEKA 4KD7A 3CL9A 1J3JA 1RX3A 2CD2A 4M2XA 4XT5A 3QLRA 1MVTA 1RX4A 4KM2A 4ELGA 2ITHA 4KJJA 1RA9A 4KYAA 5HI6A 2XW7A 1RX7A 2D0KA 4KL9A 2W3MA 1S3WA 3NXXA 4KEBA 5ECCA 3DL6A 4DPDA 3RO9A 3IA5A 4QJZD 4DFRA 1DR4A 3K47A 4X5JA 4QLGA 3F0QX 3SQYX 3GHWA 3GYFA 2HQPA 5HF0X 1DRAA 2BLCA 3SRQX 3KFYA 4ELHA 8DFRA 4QLEA 3TD8A 1PDBA 3FS6A 2CIGA 1J3KA 3TQAA 5DXVA 5HPBA 3RG9A 4M6LA 3DGAA 3FYWX 3SGYA 4P68A 4DPHA 4QHVA 4X5FA 4EIGA 1RX8A 3F8ZA 4X5IA 5HSRA 3F8YA 5FDAA 3DL5A 1RA3A 2W9GA 3SRWX 1DR1A 4DDRA 5JA3A 3DAUA 1RC4A 3FQFA 5U27A 1LUDA 2OBCA 2W3AA 3CLBA 3NZ6X 3R33A 3IROA 1TDRA 1LY3A 3QLWA 3FRDX 4NX6A 3KY8A 2D5NA 2ANQA 3KJSA 2ZZAA 3M08A 1JUVA 4X5HA 4KLXA 1YHOA 1HFQA 3I3RA 3K45A 1DYJA 1RB2A 3IA4A 3CSEA 3S3VA 3GHVA 4I13A 4KJLA 2C2TA 2HM9A 3NTZA 4OSGA 3OAFA 2W3WA 4QJCA 1DLRA 1DG5A 5HUIA 3E0BA 1RX2A 1JOLA 1M7AA 1MVSA 3QL0A 3JW5A 3ZPCA 1DRBA 4P3QA 3FQVA 2FZIA 1DREA 4ELBA 3QG2A 3L3RA 1CD2A 3F0XX 3QL3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PSS A;  1J3I A;  4QLF A;  3GI2 A;  4M7U A;  3JW3 A;  1OHK A;  2W3V A;  4Q67 A;  3TQ8 A;  1RE7 A;  3TQ9 A;  4QI9 A;  3OCH A;  4HOE A;  4KM0 A;  3S7A A;  1U72 A;  3NRR A;  1VJ3 A;  5HQY A;  3SRS X;  1AO8 A;  2DRC A;  4XE6 X;  5HVB A;  5ECX A;  3QLS A;  3F0U X;  3IX9 A;  2GD9 A;  1RG7 A;  1U70 A;  4X5G A;  1KMS A;  4LAG X;  1RX5 A;  3F91 A;  1DG7 A;  1DHI A;  4XT4 A;  3JWF A;  3DFR A;  3JTW A;  3DAT A;  1IA2 A;  3FRA X;  5HVE A;  4XT8 A;  1RB3 A;  4FGH A;  1KMV A;  1DR5 A;  4Q0E A;  1DLS A;  5U26 A;  3QLY A;  1BZF A;  3SH2 A;  1HFP A;  1AOE A;  3SAI A;  1RX9 A;  4PST A;  5CC9 A;  3FRB X;  4KJK A;  5E8Q A;  3JWM A;  5HQZ A;  3NZB X;  2H2Q A;  4H96 A;  3VCO A;  1RA2 A;  2FZJ A;  3LG4 A;  1BOZ A;  2W9H A;  3FY9 X;  3SA1 A;  5HT5 A;  3I8A X;  1DDR A;  2W3B A;  2QK8 A;  4XT6 A;  1RH3 A;  4G8Z X;  3FRF X;  4HOG A;  1ZDR A;  1HFR A;  4PDJ A;  4LEK X;  2OIP A;  2W9S A;  4RGC A;  3QLZ A;  3EEM A;  3INV A;  3FQZ A;  4HOF A;  2AZN A;  3EEJ A;  4ELF A;  1RA1 A;  4Q6A A;  3NXV A;  2INQ A;  3F0S X;  1M78 A;  1RX6 A;  3UM5 A;  1DR6 A;  3JWC A;  3JWK A;  3QYL A;  1DYI A;  2HXV A;  4PTJ A;  3ROA A;  5HSU A;  4EIZ A;  3D80 A;  1DR3 A;  4LAH X;  3JVX A;  3IRN A;  3HJ3 A;  1D1G A;  3NZ9 X;  2O7P A;  3FY8 X;  4XRB A;  3UM6 A;  3NXY A;  1SEJ A;  4P66 A;  3N0H A;  4M7V A;  3TQB A;  4KNE A;  3DG8 A;  1IA3 A;  1CZ3 A;  3Q1H A;  4EIL A;  4Q0D A;  4H98 A;  3QGT A;  3SRR X;  1DHJ A;  1RF7 A;  3FRE X;  4XEC X;  3NXO A;  3FL9 A;  4IXF X;  4HA7 A;  2ANO A;  1QZF A;  1DR7 A;  4ECK A;  2DHF A;  1RA8 A;  4M6K A;  3S9U A;  4KY4 A;  3NXT A;  5JG0 X;  1JOM A;  3FL8 A;  3CD2 A;  3K2H A;  2BL9 A;  3SR5 X;  3NZC X;  5EAJ A;  2W9T A;  4FGG A;  4LAE X;  1KLK A;  1DDS A;  1DHF A;  1S3V A;  2C2S A;  3NZA X;  1IA1 A;  1S3Y A;  1DAJ A;  4IXE D;  4DP3 A;  3SRU X;  3EEL A;  4NX7 A;  3QLX A;  3D84 X;  3F0V X;  4KBN A;  1DR2 A;  4M6J A;  1M79 A;  5DFR A;  3F0B X;  4KFJ A;  2L28 A;  3NXR A;  1DRF A;  4FHB A;  3K74 A;  1E26 A;  3FYV X;  2LF1 A;  1PD8 A;  3KGY A;  4ELE A;  3QYO A;  4G3M A;  4I1N A;  4HA9 A;  3IRM A;  5HT4 A;  2FZH A;  4P3R A;  3KJR A;  3EIG A;  2KGK A;  3UM8 A;  3HBB A;  3QFX A;  4OR7 A;  3JSU A;  3FQC A;  4CD2 A;  3FQ0 A;  4XT7 A;  1OHJ A;  3ZPG A;  4KY8 A;  3GHC A;  1RD7 A;  1DG8 A;  1DYR A;  2P4G A;  5CCC A;  4H97 A;  1U71 A;  3EX8 A;  3NU0 A;  1VDR A;  3SA2 A;  3NZD A;  4KAK A;  4PSY A;  1DIS A;  2G6V A;  1DF7 A;  4TU5 X;  4EJ1 A;  4H95 A;  7DFR A;  1RX1 A;  2BLA A;  2JYB A;  4G95 A;  5HF2 X;  4PTH A;  4IXG X;  1DRH A;  1DIU A;  1IA4 A;  3DRC A;  3M09 A;  2B3Z A;  2BLB A;  3FQO A;  1S3U A;  6DFR A;  1PD9 A;  1AI9 A;  4GH8 A;  1DYH A;  1LY4 A;  3EEK A;  4KD7 A;  3CL9 A;  1J3J A;  1RX3 A;  2CD2 A;  4M2X A;  4XT5 A;  3QLR A;  1MVT A;  1RX4 A;  4KM2 A;  4ELG A;  2ITH A;  4KJJ A;  1RA9 A;  4KYA A;  5HI6 A;  2XW7 A;  1RX7 A;  2D0K A;  4KL9 A;  2W3M A;  1S3W A;  3NXX A;  4KEB A;  5ECC A;  3DL6 A;  4DPD A;  3RO9 A;  3IA5 A;  4QJZ D;  4DFR A;  1DR4 A;  3K47 A;  4X5J A;  4QLG A;  3F0Q X;  3SQY X;  3GHW A;  3GYF A;  2HQP A;  5HF0 X;  1DRA A;  2BLC A;  3SRQ X;  3KFY A;  4ELH A;  8DFR A;  4QLE A;  3TD8 A;  1PDB A;  3FS6 A;  2CIG A;  1J3K A;  3TQA A;  5DXV A;  5HPB A;  3RG9 A;  4M6L A;  3DGA A;  3FYW X;  3SGY A;  4P68 A;  4DPH A;  4QHV A;  4X5F A;  4EIG A;  1RX8 A;  3F8Z A;  4X5I A;  5HSR A;  3F8Y A;  5FDA A;  3DL5 A;  1RA3 A;  2W9G A;  3SRW X;  1DR1 A;  4DDR A;  5JA3 A;  3DAU A;  1RC4 A;  3FQF A;  5U27 A;  1LUD A;  2OBC A;  2W3A A;  3CLB A;  3NZ6 X;  3R33 A;  3IRO A;  1TDR A;  1LY3 A;  3QLW A;  3FRD X;  4NX6 A;  3KY8 A;  2D5N A;  2ANQ A;  3KJS A;  2ZZA A;  3M08 A;  1JUV A;  4X5H A;  4KLX A;  1YHO A;  1HFQ A;  3I3R A;  3K45 A;  1DYJ A;  1RB2 A;  3IA4 A;  3CSE A;  3S3V A;  3GHV A;  4I13 A;  4KJL A;  2C2T A;  2HM9 A;  3NTZ A;  4OSG A;  3OAF A;  2W3W A;  4QJC A;  1DLR A;  1DG5 A;  5HUI A;  3E0B A;  1RX2 A;  1JOL A;  1M7A A;  1MVS A;  3QL0 A;  3JW5 A;  3ZPC A;  1DRB A;  4P3Q A;  3FQV A;  2FZI A;  1DRE A;  4ELB A;  3QG2 A;  3L3R A;  1CD2 A;  3F0X X;  3QL3 A; 
#chains in the Genus database with same CATH topology
 4PSS A;  1J3I A;  4QLF A;  3GI2 A;  4M7U A;  3JW3 A;  1OHK A;  2W3V A;  4Q67 A;  3TQ8 A;  1RE7 A;  3TQ9 A;  4QI9 A;  3OCH A;  4HOE A;  4KM0 A;  3S7A A;  1U72 A;  3NRR A;  1VJ3 A;  5HQY A;  3SRS X;  1AO8 A;  2DRC A;  4XE6 X;  5HVB A;  5ECX A;  3QLS A;  3F0U X;  3IX9 A;  2GD9 A;  1RG7 A;  1U70 A;  4X5G A;  1KMS A;  4LAG X;  1RX5 A;  3F91 A;  1DG7 A;  1DHI A;  4XT4 A;  3JWF A;  3DFR A;  3JTW A;  3DAT A;  1IA2 A;  3FRA X;  5HVE A;  4XT8 A;  1RB3 A;  4FGH A;  1KMV A;  1DR5 A;  4Q0E A;  1DLS A;  5U26 A;  3QLY A;  1BZF A;  3SH2 A;  1HFP A;  1AOE A;  3SAI A;  1RX9 A;  4PST A;  5CC9 A;  3FRB X;  4KJK A;  5E8Q A;  3JWM A;  5HQZ A;  3NZB X;  2H2Q A;  4H96 A;  3VCO A;  1RA2 A;  2FZJ A;  3LG4 A;  1BOZ A;  2W9H A;  3FY9 X;  3SA1 A;  5HT5 A;  3I8A X;  1DDR A;  2W3B A;  2QK8 A;  4XT6 A;  1RH3 A;  4G8Z X;  3FRF X;  4HOG A;  1ZDR A;  1HFR A;  4PDJ A;  4LEK X;  2OIP A;  2W9S A;  4RGC A;  3QLZ A;  3EEM A;  3INV A;  3FQZ A;  4HOF A;  2AZN A;  3EEJ A;  4ELF A;  1RA1 A;  4Q6A A;  3NXV A;  2INQ A;  3F0S X;  1M78 A;  1RX6 A;  3UM5 A;  1DR6 A;  3JWC A;  3JWK A;  3QYL A;  1DYI A;  2HXV A;  4PTJ A;  3ROA A;  5HSU A;  4EIZ A;  3D80 A;  1DR3 A;  4LAH X;  3JVX A;  3IRN A;  3HJ3 A;  1D1G A;  3NZ9 X;  2O7P A;  3FY8 X;  4XRB A;  3UM6 A;  3NXY A;  1SEJ A;  4P66 A;  3N0H A;  4M7V A;  3TQB A;  4KNE A;  3DG8 A;  1IA3 A;  1CZ3 A;  3Q1H A;  4EIL A;  4Q0D A;  4H98 A;  3QGT A;  3SRR X;  1DHJ A;  1RF7 A;  3FRE X;  4XEC X;  3NXO A;  3FL9 A;  4IXF X;  4HA7 A;  2ANO A;  1QZF A;  1DR7 A;  4ECK A;  2DHF A;  1RA8 A;  4M6K A;  3S9U A;  4KY4 A;  3NXT A;  5JG0 X;  1JOM A;  3FL8 A;  3CD2 A;  3K2H A;  2BL9 A;  3SR5 X;  3NZC X;  5EAJ A;  2W9T A;  4FGG A;  4LAE X;  1KLK A;  1DDS A;  1DHF A;  1S3V A;  2C2S A;  3NZA X;  1IA1 A;  1S3Y A;  1DAJ A;  4IXE D;  4DP3 A;  3SRU X;  3EEL A;  4NX7 A;  3QLX A;  3D84 X;  3F0V X;  4KBN A;  1DR2 A;  4M6J A;  1M79 A;  5DFR A;  3F0B X;  4KFJ A;  2L28 A;  3NXR A;  1DRF A;  4FHB A;  3K74 A;  1E26 A;  3FYV X;  2LF1 A;  1PD8 A;  3KGY A;  4ELE A;  3QYO A;  4G3M A;  4I1N A;  4HA9 A;  3IRM A;  5HT4 A;  2FZH A;  4P3R A;  3KJR A;  3EIG A;  2KGK A;  3UM8 A;  3HBB A;  3QFX A;  4OR7 A;  3JSU A;  3FQC A;  4CD2 A;  3FQ0 A;  4XT7 A;  1OHJ A;  3ZPG A;  4KY8 A;  3GHC A;  1RD7 A;  1DG8 A;  1DYR A;  2P4G A;  5CCC A;  4H97 A;  1U71 A;  3EX8 A;  3NU0 A;  1VDR A;  3SA2 A;  3NZD A;  4KAK A;  4PSY A;  1DIS A;  2G6V A;  1DF7 A;  4TU5 X;  4EJ1 A;  4H95 A;  7DFR A;  1RX1 A;  2BLA A;  2JYB A;  4G95 A;  5HF2 X;  4PTH A;  4IXG X;  1DRH A;  1DIU A;  1IA4 A;  3DRC A;  3M09 A;  2B3Z A;  2BLB A;  3FQO A;  1S3U A;  6DFR A;  1PD9 A;  1AI9 A;  4GH8 A;  1DYH A;  1LY4 A;  3EEK A;  4KD7 A;  3CL9 A;  1J3J A;  1RX3 A;  2CD2 A;  4M2X A;  4XT5 A;  3QLR A;  1MVT A;  1RX4 A;  4KM2 A;  4ELG A;  2ITH A;  4KJJ A;  1RA9 A;  4KYA A;  5HI6 A;  2XW7 A;  1RX7 A;  2D0K A;  4KL9 A;  2W3M A;  1S3W A;  3NXX A;  4KEB A;  5ECC A;  3DL6 A;  4DPD A;  3RO9 A;  3IA5 A;  4QJZ D;  4DFR A;  1DR4 A;  3K47 A;  4X5J A;  4QLG A;  3F0Q X;  3SQY X;  3GHW A;  3GYF A;  2HQP A;  5HF0 X;  1DRA A;  2BLC A;  3SRQ X;  3KFY A;  4ELH A;  8DFR A;  4QLE A;  3TD8 A;  1PDB A;  3FS6 A;  2CIG A;  1J3K A;  3TQA A;  5DXV A;  5HPB A;  3RG9 A;  4M6L A;  3DGA A;  3FYW X;  3SGY A;  4P68 A;  4DPH A;  4QHV A;  4X5F A;  4EIG A;  1RX8 A;  3F8Z A;  4X5I A;  5HSR A;  3F8Y A;  5FDA A;  3DL5 A;  1RA3 A;  2W9G A;  3SRW X;  1DR1 A;  4DDR A;  5JA3 A;  3DAU A;  1RC4 A;  3FQF A;  5U27 A;  1LUD A;  2OBC A;  2W3A A;  3CLB A;  3NZ6 X;  3R33 A;  3IRO A;  1TDR A;  1LY3 A;  3QLW A;  3FRD X;  4NX6 A;  3KY8 A;  2D5N A;  2ANQ A;  3KJS A;  2ZZA A;  3M08 A;  1JUV A;  4X5H A;  4KLX A;  1YHO A;  1HFQ A;  3I3R A;  3K45 A;  1DYJ A;  1RB2 A;  3IA4 A;  3CSE A;  3S3V A;  3GHV A;  4I13 A;  4KJL A;  2C2T A;  2HM9 A;  3NTZ A;  4OSG A;  3OAF A;  2W3W A;  4QJC A;  1DLR A;  1DG5 A;  5HUI A;  3E0B A;  1RX2 A;  1JOL A;  1M7A A;  1MVS A;  3QL0 A;  3JW5 A;  3ZPC A;  1DRB A;  4P3Q A;  3FQV A;  2FZI A;  1DRE A;  4ELB A;  3QG2 A;  3L3R A;  1CD2 A;  3F0X X;  3QL3 A; 
#chains in the Genus database with same CATH homology
 4PSS A;  1J3I A;  4QLF A;  3GI2 A;  4M7U A;  3JW3 A;  1OHK A;  2W3V A;  4Q67 A;  3TQ8 A;  1RE7 A;  3TQ9 A;  4QI9 A;  3OCH A;  4HOE A;  4KM0 A;  3S7A A;  1U72 A;  3NRR A;  1VJ3 A;  5HQY A;  3SRS X;  1AO8 A;  2DRC A;  4XE6 X;  5HVB A;  5ECX A;  3QLS A;  3F0U X;  3IX9 A;  2GD9 A;  1RG7 A;  1U70 A;  4X5G A;  1KMS A;  4LAG X;  1RX5 A;  3F91 A;  1DG7 A;  1DHI A;  4XT4 A;  3JWF A;  3DFR A;  3JTW A;  3DAT A;  1IA2 A;  3FRA X;  5HVE A;  4XT8 A;  1RB3 A;  4FGH A;  1KMV A;  1DR5 A;  4Q0E A;  1DLS A;  5U26 A;  3QLY A;  1BZF A;  3SH2 A;  1HFP A;  1AOE A;  3SAI A;  1RX9 A;  4PST A;  5CC9 A;  3FRB X;  4KJK A;  5E8Q A;  3JWM A;  5HQZ A;  3NZB X;  2H2Q A;  4H96 A;  3VCO A;  1RA2 A;  2FZJ A;  3LG4 A;  1BOZ A;  2W9H A;  3FY9 X;  3SA1 A;  5HT5 A;  3I8A X;  1DDR A;  2W3B A;  2QK8 A;  4XT6 A;  1RH3 A;  4G8Z X;  3FRF X;  4HOG A;  1ZDR A;  1HFR A;  4PDJ A;  4LEK X;  2OIP A;  2W9S A;  4RGC A;  3QLZ A;  3EEM A;  3INV A;  3FQZ A;  4HOF A;  2AZN A;  3EEJ A;  4ELF A;  1RA1 A;  4Q6A A;  3NXV A;  2INQ A;  3F0S X;  1M78 A;  1RX6 A;  3UM5 A;  1DR6 A;  3JWC A;  3JWK A;  3QYL A;  1DYI A;  2HXV A;  4PTJ A;  3ROA A;  5HSU A;  4EIZ A;  3D80 A;  1DR3 A;  4LAH X;  3JVX A;  3IRN A;  3HJ3 A;  1D1G A;  3NZ9 X;  2O7P A;  3FY8 X;  4XRB A;  3UM6 A;  3NXY A;  1SEJ A;  4P66 A;  3N0H A;  4M7V A;  3TQB A;  4KNE A;  3DG8 A;  1IA3 A;  1CZ3 A;  3Q1H A;  4EIL A;  4Q0D A;  4H98 A;  3QGT A;  3SRR X;  1DHJ A;  1RF7 A;  3FRE X;  4XEC X;  3NXO A;  3FL9 A;  4IXF X;  4HA7 A;  2ANO A;  1QZF A;  1DR7 A;  4ECK A;  2DHF A;  1RA8 A;  4M6K A;  3S9U A;  4KY4 A;  3NXT A;  5JG0 X;  1JOM A;  3FL8 A;  3CD2 A;  3K2H A;  2BL9 A;  3SR5 X;  3NZC X;  5EAJ A;  2W9T A;  4FGG A;  4LAE X;  1KLK A;  1DDS A;  1DHF A;  1S3V A;  2C2S A;  3NZA X;  1IA1 A;  1S3Y A;  1DAJ A;  4IXE D;  4DP3 A;  3SRU X;  3EEL A;  4NX7 A;  3QLX A;  3D84 X;  3F0V X;  4KBN A;  1DR2 A;  4M6J A;  1M79 A;  5DFR A;  3F0B X;  4KFJ A;  2L28 A;  3NXR A;  1DRF A;  4FHB A;  3K74 A;  1E26 A;  3FYV X;  2LF1 A;  1PD8 A;  3KGY A;  4ELE A;  3QYO A;  4G3M A;  4I1N A;  4HA9 A;  3IRM A;  5HT4 A;  2FZH A;  4P3R A;  3KJR A;  3EIG A;  2KGK A;  3UM8 A;  3HBB A;  3QFX A;  4OR7 A;  3JSU A;  3FQC A;  4CD2 A;  3FQ0 A;  4XT7 A;  1OHJ A;  3ZPG A;  4KY8 A;  3GHC A;  1RD7 A;  1DG8 A;  1DYR A;  2P4G A;  5CCC A;  4H97 A;  1U71 A;  3EX8 A;  3NU0 A;  1VDR A;  3SA2 A;  3NZD A;  4KAK A;  4PSY A;  1DIS A;  2G6V A;  1DF7 A;  4TU5 X;  4EJ1 A;  4H95 A;  7DFR A;  1RX1 A;  2BLA A;  2JYB A;  4G95 A;  5HF2 X;  4PTH A;  4IXG X;  1DRH A;  1DIU A;  1IA4 A;  3DRC A;  3M09 A;  2B3Z A;  2BLB A;  3FQO A;  1S3U A;  6DFR A;  1PD9 A;  1AI9 A;  4GH8 A;  1DYH A;  1LY4 A;  3EEK A;  4KD7 A;  3CL9 A;  1J3J A;  1RX3 A;  2CD2 A;  4M2X A;  4XT5 A;  3QLR A;  1MVT A;  1RX4 A;  4KM2 A;  4ELG A;  2ITH A;  4KJJ A;  1RA9 A;  4KYA A;  5HI6 A;  2XW7 A;  1RX7 A;  2D0K A;  4KL9 A;  2W3M A;  1S3W A;  3NXX A;  4KEB A;  5ECC A;  3DL6 A;  4DPD A;  3RO9 A;  3IA5 A;  4QJZ D;  4DFR A;  1DR4 A;  3K47 A;  4X5J A;  4QLG A;  3F0Q X;  3SQY X;  3GHW A;  3GYF A;  2HQP A;  5HF0 X;  1DRA A;  2BLC A;  3SRQ X;  3KFY A;  4ELH A;  8DFR A;  4QLE A;  3TD8 A;  1PDB A;  3FS6 A;  2CIG A;  1J3K A;  3TQA A;  5DXV A;  5HPB A;  3RG9 A;  4M6L A;  3DGA A;  3FYW X;  3SGY A;  4P68 A;  4DPH A;  4QHV A;  4X5F A;  4EIG A;  1RX8 A;  3F8Z A;  4X5I A;  5HSR A;  3F8Y A;  5FDA A;  3DL5 A;  1RA3 A;  2W9G A;  3SRW X;  1DR1 A;  4DDR A;  5JA3 A;  3DAU A;  1RC4 A;  3FQF A;  5U27 A;  1LUD A;  2OBC A;  2W3A A;  3CLB A;  3NZ6 X;  3R33 A;  3IRO A;  1TDR A;  1LY3 A;  3QLW A;  3FRD X;  4NX6 A;  3KY8 A;  2D5N A;  2ANQ A;  3KJS A;  2ZZA A;  3M08 A;  1JUV A;  4X5H A;  4KLX A;  1YHO A;  1HFQ A;  3I3R A;  3K45 A;  1DYJ A;  1RB2 A;  3IA4 A;  3CSE A;  3S3V A;  3GHV A;  4I13 A;  4KJL A;  2C2T A;  2HM9 A;  3NTZ A;  4OSG A;  3OAF A;  2W3W A;  4QJC A;  1DLR A;  1DG5 A;  5HUI A;  3E0B A;  1RX2 A;  1JOL A;  1M7A A;  1MVS A;  3QL0 A;  3JW5 A;  3ZPC A;  1DRB A;  4P3Q A;  3FQV A;  2FZI A;  1DRE A;  4ELB A;  3QG2 A;  3L3R A;  1CD2 A;  3F0X X;  3QL3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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