4I1NA

R104a-ca1697 nanobody binding to the binary dhfr.folate complex
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring an alternative antibody interaction mechanism
rcsb
molecule tags Oxidoreductase/immune system
source organism Escherichia coli
molecule keywords Dihydrofolate reductase
total genus 47
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2012-11-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4i1nA00
3DFRA 1DDRA 1JUVA 3SA1A 2HM9A 1DYIA 3FQOA 4I1NA 4Q0DA 5U27A 1IA2A 1D1GA 1DIUA 1DDSA 1JOLA 1RA2A 4G3MA 5HQYA 3FQCA 1CZ3A 1DREA 3RO9A 1HFPA 4IXGX 4ELGA 1AO8A 3F0VX 4QI9A 4KBNA 5HSUA 4XT5A 1DRBA 2OBCA 2HXVA 3GHVA 3NXOA 4LAHX 4PSYA 4PTHA 3TQ9A 3ZPGA 3F0UX 4NX7A 3NXTA 3VCOA 3QG2A 3EX8A 3F0SX 2ANOA 4Q67A 2BLCA 3L3RA 1DR5A 1U71A 5HPBA 1AI9A 1DHFA 1U70A 4P66A 4KD7A 1DR2A 1RB3A 1J3IA 4DPDA 4X5JA 1PD8A 3HJ3A 1AOEA 4HA7A 4QJCA 1DR3A 3EEJA 3QGTA 4M6KA 2KGKA 3M09A 3DRCA 4M6JA 1DG8A 3INVA 4KJLA 4ELEA 4HOGA 1U72A 3JTWA 1IA4A 4M7VA 4KLXA 3SA2A 3SAIA 3KJRA 1CD2A 1M79A 1DRHA 5CCCA 3QYOA 2W9HA 1ZDRA 2BLBA 2FZJA 3ZPCA 1J3JA 1HFQA 1MVSA 1RX6A 5HT4A 2ZZAA 3FREX 3SRWX 3F0BX 3NXYA 3TQAA 3F0QX 1M78A 4FHBA 2W3WA 1S3YA 4EIZA 3NZ6X 1RC4A 4OSGA 3FY9X 1RX4A 3UM8A 4M6LA 4X5IA 5HI6A 3QLSA 3IRNA 3CL9A 5HUIA 2D5NA 3FRFX 4KY8A 2W3VA 1BZFA 4KNEA 1DR1A 3DGAA 3SRUX 1RX5A 4H95A 2L28A 2D0KA 2CD2A 1PDBA 4FGGA 3ROAA 1VDRA 3DAUA 4XT6A 4KY4A 3F91A 3GI2A 5DFRA 1LUDA 3QLYA 2OIPA 7DFRA 3FRAX 1DHIA 3F8YA 4PSSA 2W3MA 3FQFA 5HT5A 1RX7A 2BL9A 3QYLA 4HA9A 5U26A 3NZDA 5FDAA 3FL8A 3I8AX 1IA3A 5HQZA 3JVXA 1DF7A 3NXXA 1RA1A 3KJSA 3QLXA 2W9SA 3CD2A 3EEKA 4G95A 1LY4A 4HOFA 2FZHA 1JOMA 1E26A 4DPHA 3FL9A 2AZNA 3IA4A 1RA9A 4PTJA 3TQBA 5EAJA 4P3QA 3NZAX 2C2SA 1DAJA 3QLZA 4KJJA 3DG8A 3TQ8A 1KMVA 3K45A 1RE7A 2P4GA 3JSUA 4P3RA 3NXVA 4KM0A 3JWFA 6DFRA 3OCHA 2W3AA 3SRQX 1DR6A 4KFJA 3HBBA 1RD7A 3GHCA 1YHOA 5E8QA 1RX2A 3NTZA 1KLKA 3D80A 2HQPA 4XECX 4ECKA 1IA1A 1DHJA 1RG7A 2INQA 4Q6AA 3SQYX 3Q1HA 5HVBA 1RH3A 3QLWA 3UM5A 3FS6A 3M08A 4X5GA 1RA8A 1S3UA 3F8ZA 1DG7A 3FQVA 1DYHA 3OAFA 3SH2A 4QLFA 3EELA 1DG5A 3FRBX 1DRFA 3LG4A 2LF1A 4X5FA 3KFYA 3QLRA 3R33A 5HVEA 3SGYA 3KY8A 1VJ3A 3FYWX 3QL0A 4DDRA 1DYJA 4OR7A 5ECCA 2CIGA 4LEKX 3I3RA 1RX1A 3S7AA 3JWMA 5JG0X 2C2TA 2ITHA 3JWCA 4P68A 4KJKA 3NU0A 1DR4A 3E0BA 4XT4A 3K47A 2JYBA 4ELBA 1DLSA 4QHVA 1RX8A 2BLAA 4PDJA 3CLBA 2DHFA 3GYFA 3IA5A 4M2XA 2B3ZA 3FQZA 1MVTA 4NX6A 2FZIA 3JW5A 1DLRA 3K2HA 2DRCA 4XT7A 3UM6A 3NXRA 4I13A 4LAGX 3IX9A 3FQ0A 5JA3A 2ANQA 4EIGA 1PD9A 2O7PA 3S3VA 4X5HA 3RG9A 4EILA 1KMSA 4FGHA 1RA3A 5HF2X 1RX9A 1DR7A 1DISA 3FY8X 1LY3A 3CSEA 4KEBA 1BOZA 4EJ1A 4GH8A 4H96A 4IXED 5HF0X 3NRRA 3DATA 1HFRA 4QJZD 3SRSX 1OHKA 4H97A 4XRBA 5DXVA 4XT8A 4H98A 3JWKA 3SRRX 1RX3A 4LAEX 3IROA 3JW3A 4ELFA 2W9GA 2W9TA 3IRMA 4CD2A 3D84X 4DP3A 1DRAA 4RGCA 4G8ZX 1SEJA 1TDRA 1RF7A 5CC9A 3N0HA 3EEMA 2W3BA 4M7UA 3DL5A 3KGYA 1QZFA 4QLGA 4KYAA 4XE6X 4QLEA 3QL3A 4DFRA 1RB2A 1S3VA 1S3WA 3NZ9X 8DFRA 4ELHA 1DYRA 4Q0EA 3SR5X 4KM2A 3DL6A 2G6VA 3NZBX 4PSTA 2H2QA 3QFXA 3EIGA 4IXFX 4HOEA 2QK8A 1OHJA 3F0XX 3TD8A 3S9UA 1M7AA 4KL9A 3FYVX 3K74A 3GHWA 1J3KA 5HSRA 5ECXA 2XW7A 2GD9A 3NZCX 3FRDX 4TU5X 4KAKA
chains in the Genus database with same CATH superfamily
3DFRA 1DDRA 1JUVA 3SA1A 2HM9A 1DYIA 3FQOA 4I1NA 4Q0DA 5U27A 1IA2A 1D1GA 1DIUA 1DDSA 1JOLA 1RA2A 4G3MA 5HQYA 3FQCA 1CZ3A 1DREA 3RO9A 1HFPA 4IXGX 4ELGA 1AO8A 3F0VX 4QI9A 4KBNA 5HSUA 4XT5A 1DRBA 2OBCA 2HXVA 3GHVA 3NXOA 4LAHX 4PSYA 4PTHA 3TQ9A 3ZPGA 3F0UX 4NX7A 3NXTA 3VCOA 3QG2A 3EX8A 3F0SX 2ANOA 4Q67A 2BLCA 3L3RA 1DR5A 1U71A 5HPBA 1AI9A 1DHFA 1U70A 4P66A 4KD7A 1DR2A 1RB3A 1J3IA 4DPDA 4X5JA 1PD8A 3HJ3A 1AOEA 4HA7A 4QJCA 1DR3A 3EEJA 3QGTA 4M6KA 2KGKA 3M09A 3DRCA 4M6JA 1DG8A 3INVA 4KJLA 4ELEA 4HOGA 1U72A 3JTWA 1IA4A 4M7VA 4KLXA 3SA2A 3SAIA 3KJRA 1CD2A 1M79A 1DRHA 5CCCA 3QYOA 2W9HA 1ZDRA 2BLBA 2FZJA 3ZPCA 1J3JA 1HFQA 1MVSA 1RX6A 5HT4A 2ZZAA 3FREX 3SRWX 3F0BX 3NXYA 3TQAA 3F0QX 1M78A 4FHBA 2W3WA 1S3YA 4EIZA 3NZ6X 1RC4A 4OSGA 3FY9X 1RX4A 3UM8A 4M6LA 4X5IA 5HI6A 3QLSA 3IRNA 3CL9A 5HUIA 2D5NA 3FRFX 4KY8A 2W3VA 1BZFA 4KNEA 1DR1A 3DGAA 3SRUX 1RX5A 4H95A 2L28A 2D0KA 2CD2A 1PDBA 4FGGA 3ROAA 1VDRA 3DAUA 4XT6A 4KY4A 3F91A 3GI2A 5DFRA 1LUDA 3QLYA 2OIPA 7DFRA 3FRAX 1DHIA 3F8YA 4PSSA 2W3MA 3FQFA 5HT5A 1RX7A 2BL9A 3QYLA 4HA9A 5U26A 3NZDA 5FDAA 3FL8A 3I8AX 1IA3A 5HQZA 3JVXA 1DF7A 3NXXA 1RA1A 3KJSA 3QLXA 2W9SA 3CD2A 3EEKA 4G95A 1LY4A 4HOFA 2FZHA 1JOMA 1E26A 4DPHA 3FL9A 2AZNA 3IA4A 1RA9A 4PTJA 3TQBA 5EAJA 4P3QA 3NZAX 2C2SA 1DAJA 3QLZA 4KJJA 3DG8A 3TQ8A 1KMVA 3K45A 1RE7A 2P4GA 3JSUA 4P3RA 3NXVA 4KM0A 3JWFA 6DFRA 3OCHA 2W3AA 3SRQX 1DR6A 4KFJA 3HBBA 1RD7A 3GHCA 1YHOA 5E8QA 1RX2A 3NTZA 1KLKA 3D80A 2HQPA 4XECX 4ECKA 1IA1A 1DHJA 1RG7A 2INQA 4Q6AA 3SQYX 3Q1HA 5HVBA 1RH3A 3QLWA 3UM5A 3FS6A 3M08A 4X5GA 1RA8A 1S3UA 3F8ZA 1DG7A 3FQVA 1DYHA 3OAFA 3SH2A 4QLFA 3EELA 1DG5A 3FRBX 1DRFA 3LG4A 2LF1A 4X5FA 3KFYA 3QLRA 3R33A 5HVEA 3SGYA 3KY8A 1VJ3A 3FYWX 3QL0A 4DDRA 1DYJA 4OR7A 5ECCA 2CIGA 4LEKX 3I3RA 1RX1A 3S7AA 3JWMA 5JG0X 2C2TA 2ITHA 3JWCA 4P68A 4KJKA 3NU0A 1DR4A 3E0BA 4XT4A 3K47A 2JYBA 4ELBA 1DLSA 4QHVA 1RX8A 2BLAA 4PDJA 3CLBA 2DHFA 3GYFA 3IA5A 4M2XA 2B3ZA 3FQZA 1MVTA 4NX6A 2FZIA 3JW5A 1DLRA 3K2HA 2DRCA 4XT7A 3UM6A 3NXRA 4I13A 4LAGX 3IX9A 3FQ0A 5JA3A 2ANQA 4EIGA 1PD9A 2O7PA 3S3VA 4X5HA 3RG9A 4EILA 1KMSA 4FGHA 1RA3A 5HF2X 1RX9A 1DR7A 1DISA 3FY8X 1LY3A 3CSEA 4KEBA 1BOZA 4EJ1A 4GH8A 4H96A 4IXED 5HF0X 3NRRA 3DATA 1HFRA 4QJZD 3SRSX 1OHKA 4H97A 4XRBA 5DXVA 4XT8A 4H98A 3JWKA 3SRRX 1RX3A 4LAEX 3IROA 3JW3A 4ELFA 2W9GA 2W9TA 3IRMA 4CD2A 3D84X 4DP3A 1DRAA 4RGCA 4G8ZX 1SEJA 1TDRA 1RF7A 5CC9A 3N0HA 3EEMA 2W3BA 4M7UA 3DL5A 3KGYA 1QZFA 4QLGA 4KYAA 4XE6X 4QLEA 3QL3A 4DFRA 1RB2A 1S3VA 1S3WA 3NZ9X 8DFRA 4ELHA 1DYRA 4Q0EA 3SR5X 4KM2A 3DL6A 2G6VA 3NZBX 4PSTA 2H2QA 3QFXA 3EIGA 4IXFX 4HOEA 2QK8A 1OHJA 3F0XX 3TD8A 3S9UA 1M7AA 4KL9A 3FYVX 3K74A 3GHWA 1J3KA 5HSRA 5ECXA 2XW7A 2GD9A 3NZCX 3FRDX 4TU5X 4KAKA
chains in the Genus database with same CATH topology
3DFRA 1DDRA 1JUVA 3SA1A 2HM9A 1DYIA 3FQOA 4I1NA 4Q0DA 5U27A 1IA2A 1D1GA 1DIUA 1DDSA 1JOLA 1RA2A 4G3MA 5HQYA 3FQCA 1CZ3A 1DREA 3RO9A 1HFPA 4IXGX 4ELGA 1AO8A 3F0VX 4QI9A 4KBNA 5HSUA 4XT5A 1DRBA 2OBCA 2HXVA 3GHVA 3NXOA 4LAHX 4PSYA 4PTHA 3TQ9A 3ZPGA 3F0UX 4NX7A 3NXTA 3VCOA 3QG2A 3EX8A 3F0SX 2ANOA 4Q67A 2BLCA 3L3RA 1DR5A 1U71A 5HPBA 1AI9A 1DHFA 1U70A 4P66A 4KD7A 1DR2A 1RB3A 1J3IA 4DPDA 4X5JA 1PD8A 3HJ3A 1AOEA 4HA7A 4QJCA 1DR3A 3EEJA 3QGTA 4M6KA 2KGKA 3M09A 3DRCA 4M6JA 1DG8A 3INVA 4KJLA 4ELEA 4HOGA 1U72A 3JTWA 1IA4A 4M7VA 4KLXA 3SA2A 3SAIA 3KJRA 1CD2A 1M79A 1DRHA 5CCCA 3QYOA 2W9HA 1ZDRA 2BLBA 2FZJA 3ZPCA 1J3JA 1HFQA 1MVSA 1RX6A 5HT4A 2ZZAA 3FREX 3SRWX 3F0BX 3NXYA 3TQAA 3F0QX 1M78A 4FHBA 2W3WA 1S3YA 4EIZA 3NZ6X 1RC4A 4OSGA 3FY9X 1RX4A 3UM8A 4M6LA 4X5IA 5HI6A 3QLSA 3IRNA 3CL9A 5HUIA 2D5NA 3FRFX 4KY8A 2W3VA 1BZFA 4KNEA 1DR1A 3DGAA 3SRUX 1RX5A 4H95A 2L28A 2D0KA 2CD2A 1PDBA 4FGGA 3ROAA 1VDRA 3DAUA 4XT6A 4KY4A 3F91A 3GI2A 5DFRA 1LUDA 3QLYA 2OIPA 7DFRA 3FRAX 1DHIA 3F8YA 4PSSA 2W3MA 3FQFA 5HT5A 1RX7A 2BL9A 3QYLA 4HA9A 5U26A 3NZDA 5FDAA 3FL8A 3I8AX 1IA3A 5HQZA 3JVXA 1DF7A 3NXXA 1RA1A 3KJSA 3QLXA 2W9SA 3CD2A 3EEKA 4G95A 1LY4A 4HOFA 2FZHA 1JOMA 1E26A 4DPHA 3FL9A 2AZNA 3IA4A 1RA9A 4PTJA 3TQBA 5EAJA 4P3QA 3NZAX 2C2SA 1DAJA 3QLZA 4KJJA 3DG8A 3TQ8A 1KMVA 3K45A 1RE7A 2P4GA 3JSUA 4P3RA 3NXVA 4KM0A 3JWFA 6DFRA 3OCHA 2W3AA 3SRQX 1DR6A 4KFJA 3HBBA 1RD7A 3GHCA 1YHOA 5E8QA 1RX2A 3NTZA 1KLKA 3D80A 2HQPA 4XECX 4ECKA 1IA1A 1DHJA 1RG7A 2INQA 4Q6AA 3SQYX 3Q1HA 5HVBA 1RH3A 3QLWA 3UM5A 3FS6A 3M08A 4X5GA 1RA8A 1S3UA 3F8ZA 1DG7A 3FQVA 1DYHA 3OAFA 3SH2A 4QLFA 3EELA 1DG5A 3FRBX 1DRFA 3LG4A 2LF1A 4X5FA 3KFYA 3QLRA 3R33A 5HVEA 3SGYA 3KY8A 1VJ3A 3FYWX 3QL0A 4DDRA 1DYJA 4OR7A 5ECCA 2CIGA 4LEKX 3I3RA 1RX1A 3S7AA 3JWMA 5JG0X 2C2TA 2ITHA 3JWCA 4P68A 4KJKA 3NU0A 1DR4A 3E0BA 4XT4A 3K47A 2JYBA 4ELBA 1DLSA 4QHVA 1RX8A 2BLAA 4PDJA 3CLBA 2DHFA 3GYFA 3IA5A 4M2XA 2B3ZA 3FQZA 1MVTA 4NX6A 2FZIA 3JW5A 1DLRA 3K2HA 2DRCA 4XT7A 3UM6A 3NXRA 4I13A 4LAGX 3IX9A 3FQ0A 5JA3A 2ANQA 4EIGA 1PD9A 2O7PA 3S3VA 4X5HA 3RG9A 4EILA 1KMSA 4FGHA 1RA3A 5HF2X 1RX9A 1DR7A 1DISA 3FY8X 1LY3A 3CSEA 4KEBA 1BOZA 4EJ1A 4GH8A 4H96A 4IXED 5HF0X 3NRRA 3DATA 1HFRA 4QJZD 3SRSX 1OHKA 4H97A 4XRBA 5DXVA 4XT8A 4H98A 3JWKA 3SRRX 1RX3A 4LAEX 3IROA 3JW3A 4ELFA 2W9GA 2W9TA 3IRMA 4CD2A 3D84X 4DP3A 1DRAA 4RGCA 4G8ZX 1SEJA 1TDRA 1RF7A 5CC9A 3N0HA 3EEMA 2W3BA 4M7UA 3DL5A 3KGYA 1QZFA 4QLGA 4KYAA 4XE6X 4QLEA 3QL3A 4DFRA 1RB2A 1S3VA 1S3WA 3NZ9X 8DFRA 4ELHA 1DYRA 4Q0EA 3SR5X 4KM2A 3DL6A 2G6VA 3NZBX 4PSTA 2H2QA 3QFXA 3EIGA 4IXFX 4HOEA 2QK8A 1OHJA 3F0XX 3TD8A 3S9UA 1M7AA 4KL9A 3FYVX 3K74A 3GHWA 1J3KA 5HSRA 5ECXA 2XW7A 2GD9A 3NZCX 3FRDX 4TU5X 4KAKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DFR A;  1DDR A;  1JUV A;  3SA1 A;  2HM9 A;  1DYI A;  3FQO A;  4I1N A;  4Q0D A;  5U27 A;  1IA2 A;  1D1G A;  1DIU A;  1DDS A;  1JOL A;  1RA2 A;  4G3M A;  5HQY A;  3FQC A;  1CZ3 A;  1DRE A;  3RO9 A;  1HFP A;  4IXG X;  4ELG A;  1AO8 A;  3F0V X;  4QI9 A;  4KBN A;  5HSU A;  4XT5 A;  1DRB A;  2OBC A;  2HXV A;  3GHV A;  3NXO A;  4LAH X;  4PSY A;  4PTH A;  3TQ9 A;  3ZPG A;  3F0U X;  4NX7 A;  3NXT A;  3VCO A;  3QG2 A;  3EX8 A;  3F0S X;  2ANO A;  4Q67 A;  2BLC A;  3L3R A;  1DR5 A;  1U71 A;  5HPB A;  1AI9 A;  1DHF A;  1U70 A;  4P66 A;  4KD7 A;  1DR2 A;  1RB3 A;  1J3I A;  4DPD A;  4X5J A;  1PD8 A;  3HJ3 A;  1AOE A;  4HA7 A;  4QJC A;  1DR3 A;  3EEJ A;  3QGT A;  4M6K A;  2KGK A;  3M09 A;  3DRC A;  4M6J A;  1DG8 A;  3INV A;  4KJL A;  4ELE A;  4HOG A;  1U72 A;  3JTW A;  1IA4 A;  4M7V A;  4KLX A;  3SA2 A;  3SAI A;  3KJR A;  1CD2 A;  1M79 A;  1DRH A;  5CCC A;  3QYO A;  2W9H A;  1ZDR A;  2BLB A;  2FZJ A;  3ZPC A;  1J3J A;  1HFQ A;  1MVS A;  1RX6 A;  5HT4 A;  2ZZA A;  3FRE X;  3SRW X;  3F0B X;  3NXY A;  3TQA A;  3F0Q X;  1M78 A;  4FHB A;  2W3W A;  1S3Y A;  4EIZ A;  3NZ6 X;  1RC4 A;  4OSG A;  3FY9 X;  1RX4 A;  3UM8 A;  4M6L A;  4X5I A;  5HI6 A;  3QLS A;  3IRN A;  3CL9 A;  5HUI A;  2D5N A;  3FRF X;  4KY8 A;  2W3V A;  1BZF A;  4KNE A;  1DR1 A;  3DGA A;  3SRU X;  1RX5 A;  4H95 A;  2L28 A;  2D0K A;  2CD2 A;  1PDB A;  4FGG A;  3ROA A;  1VDR A;  3DAU A;  4XT6 A;  4KY4 A;  3F91 A;  3GI2 A;  5DFR A;  1LUD A;  3QLY A;  2OIP A;  7DFR A;  3FRA X;  1DHI A;  3F8Y A;  4PSS A;  2W3M A;  3FQF A;  5HT5 A;  1RX7 A;  2BL9 A;  3QYL A;  4HA9 A;  5U26 A;  3NZD A;  5FDA A;  3FL8 A;  3I8A X;  1IA3 A;  5HQZ A;  3JVX A;  1DF7 A;  3NXX A;  1RA1 A;  3KJS A;  3QLX A;  2W9S A;  3CD2 A;  3EEK A;  4G95 A;  1LY4 A;  4HOF A;  2FZH A;  1JOM A;  1E26 A;  4DPH A;  3FL9 A;  2AZN A;  3IA4 A;  1RA9 A;  4PTJ A;  3TQB A;  5EAJ A;  4P3Q A;  3NZA X;  2C2S A;  1DAJ A;  3QLZ A;  4KJJ A;  3DG8 A;  3TQ8 A;  1KMV A;  3K45 A;  1RE7 A;  2P4G A;  3JSU A;  4P3R A;  3NXV A;  4KM0 A;  3JWF A;  6DFR A;  3OCH A;  2W3A A;  3SRQ X;  1DR6 A;  4KFJ A;  3HBB A;  1RD7 A;  3GHC A;  1YHO A;  5E8Q A;  1RX2 A;  3NTZ A;  1KLK A;  3D80 A;  2HQP A;  4XEC X;  4ECK A;  1IA1 A;  1DHJ A;  1RG7 A;  2INQ A;  4Q6A A;  3SQY X;  3Q1H A;  5HVB A;  1RH3 A;  3QLW A;  3UM5 A;  3FS6 A;  3M08 A;  4X5G A;  1RA8 A;  1S3U A;  3F8Z A;  1DG7 A;  3FQV A;  1DYH A;  3OAF A;  3SH2 A;  4QLF A;  3EEL A;  1DG5 A;  3FRB X;  1DRF A;  3LG4 A;  2LF1 A;  4X5F A;  3KFY A;  3QLR A;  3R33 A;  5HVE A;  3SGY A;  3KY8 A;  1VJ3 A;  3FYW X;  3QL0 A;  4DDR A;  1DYJ A;  4OR7 A;  5ECC A;  2CIG A;  4LEK X;  3I3R A;  1RX1 A;  3S7A A;  3JWM A;  5JG0 X;  2C2T A;  2ITH A;  3JWC A;  4P68 A;  4KJK A;  3NU0 A;  1DR4 A;  3E0B A;  4XT4 A;  3K47 A;  2JYB A;  4ELB A;  1DLS A;  4QHV A;  1RX8 A;  2BLA A;  4PDJ A;  3CLB A;  2DHF A;  3GYF A;  3IA5 A;  4M2X A;  2B3Z A;  3FQZ A;  1MVT A;  4NX6 A;  2FZI A;  3JW5 A;  1DLR A;  3K2H A;  2DRC A;  4XT7 A;  3UM6 A;  3NXR A;  4I13 A;  4LAG X;  3IX9 A;  3FQ0 A;  5JA3 A;  2ANQ A;  4EIG A;  1PD9 A;  2O7P A;  3S3V A;  4X5H A;  3RG9 A;  4EIL A;  1KMS A;  4FGH A;  1RA3 A;  5HF2 X;  1RX9 A;  1DR7 A;  1DIS A;  3FY8 X;  1LY3 A;  3CSE A;  4KEB A;  1BOZ A;  4EJ1 A;  4GH8 A;  4H96 A;  4IXE D;  5HF0 X;  3NRR A;  3DAT A;  1HFR A;  4QJZ D;  3SRS X;  1OHK A;  4H97 A;  4XRB A;  5DXV A;  4XT8 A;  4H98 A;  3JWK A;  3SRR X;  1RX3 A;  4LAE X;  3IRO A;  3JW3 A;  4ELF A;  2W9G A;  2W9T A;  3IRM A;  4CD2 A;  3D84 X;  4DP3 A;  1DRA A;  4RGC A;  4G8Z X;  1SEJ A;  1TDR A;  1RF7 A;  5CC9 A;  3N0H A;  3EEM A;  2W3B A;  4M7U A;  3DL5 A;  3KGY A;  1QZF A;  4QLG A;  4KYA A;  4XE6 X;  4QLE A;  3QL3 A;  4DFR A;  1RB2 A;  1S3V A;  1S3W A;  3NZ9 X;  8DFR A;  4ELH A;  1DYR A;  4Q0E A;  3SR5 X;  4KM2 A;  3DL6 A;  2G6V A;  3NZB X;  4PST A;  2H2Q A;  3QFX A;  3EIG A;  4IXF X;  4HOE A;  2QK8 A;  1OHJ A;  3F0X X;  3TD8 A;  3S9U A;  1M7A A;  4KL9 A;  3FYV X;  3K74 A;  3GHW A;  1J3K A;  5HSR A;  5ECX A;  2XW7 A;  2GD9 A;  3NZC X;  3FRD X;  4TU5 X;  4KAK A; 
#chains in the Genus database with same CATH topology
 3DFR A;  1DDR A;  1JUV A;  3SA1 A;  2HM9 A;  1DYI A;  3FQO A;  4I1N A;  4Q0D A;  5U27 A;  1IA2 A;  1D1G A;  1DIU A;  1DDS A;  1JOL A;  1RA2 A;  4G3M A;  5HQY A;  3FQC A;  1CZ3 A;  1DRE A;  3RO9 A;  1HFP A;  4IXG X;  4ELG A;  1AO8 A;  3F0V X;  4QI9 A;  4KBN A;  5HSU A;  4XT5 A;  1DRB A;  2OBC A;  2HXV A;  3GHV A;  3NXO A;  4LAH X;  4PSY A;  4PTH A;  3TQ9 A;  3ZPG A;  3F0U X;  4NX7 A;  3NXT A;  3VCO A;  3QG2 A;  3EX8 A;  3F0S X;  2ANO A;  4Q67 A;  2BLC A;  3L3R A;  1DR5 A;  1U71 A;  5HPB A;  1AI9 A;  1DHF A;  1U70 A;  4P66 A;  4KD7 A;  1DR2 A;  1RB3 A;  1J3I A;  4DPD A;  4X5J A;  1PD8 A;  3HJ3 A;  1AOE A;  4HA7 A;  4QJC A;  1DR3 A;  3EEJ A;  3QGT A;  4M6K A;  2KGK A;  3M09 A;  3DRC A;  4M6J A;  1DG8 A;  3INV A;  4KJL A;  4ELE A;  4HOG A;  1U72 A;  3JTW A;  1IA4 A;  4M7V A;  4KLX A;  3SA2 A;  3SAI A;  3KJR A;  1CD2 A;  1M79 A;  1DRH A;  5CCC A;  3QYO A;  2W9H A;  1ZDR A;  2BLB A;  2FZJ A;  3ZPC A;  1J3J A;  1HFQ A;  1MVS A;  1RX6 A;  5HT4 A;  2ZZA A;  3FRE X;  3SRW X;  3F0B X;  3NXY A;  3TQA A;  3F0Q X;  1M78 A;  4FHB A;  2W3W A;  1S3Y A;  4EIZ A;  3NZ6 X;  1RC4 A;  4OSG A;  3FY9 X;  1RX4 A;  3UM8 A;  4M6L A;  4X5I A;  5HI6 A;  3QLS A;  3IRN A;  3CL9 A;  5HUI A;  2D5N A;  3FRF X;  4KY8 A;  2W3V A;  1BZF A;  4KNE A;  1DR1 A;  3DGA A;  3SRU X;  1RX5 A;  4H95 A;  2L28 A;  2D0K A;  2CD2 A;  1PDB A;  4FGG A;  3ROA A;  1VDR A;  3DAU A;  4XT6 A;  4KY4 A;  3F91 A;  3GI2 A;  5DFR A;  1LUD A;  3QLY A;  2OIP A;  7DFR A;  3FRA X;  1DHI A;  3F8Y A;  4PSS A;  2W3M A;  3FQF A;  5HT5 A;  1RX7 A;  2BL9 A;  3QYL A;  4HA9 A;  5U26 A;  3NZD A;  5FDA A;  3FL8 A;  3I8A X;  1IA3 A;  5HQZ A;  3JVX A;  1DF7 A;  3NXX A;  1RA1 A;  3KJS A;  3QLX A;  2W9S A;  3CD2 A;  3EEK A;  4G95 A;  1LY4 A;  4HOF A;  2FZH A;  1JOM A;  1E26 A;  4DPH A;  3FL9 A;  2AZN A;  3IA4 A;  1RA9 A;  4PTJ A;  3TQB A;  5EAJ A;  4P3Q A;  3NZA X;  2C2S A;  1DAJ A;  3QLZ A;  4KJJ A;  3DG8 A;  3TQ8 A;  1KMV A;  3K45 A;  1RE7 A;  2P4G A;  3JSU A;  4P3R A;  3NXV A;  4KM0 A;  3JWF A;  6DFR A;  3OCH A;  2W3A A;  3SRQ X;  1DR6 A;  4KFJ A;  3HBB A;  1RD7 A;  3GHC A;  1YHO A;  5E8Q A;  1RX2 A;  3NTZ A;  1KLK A;  3D80 A;  2HQP A;  4XEC X;  4ECK A;  1IA1 A;  1DHJ A;  1RG7 A;  2INQ A;  4Q6A A;  3SQY X;  3Q1H A;  5HVB A;  1RH3 A;  3QLW A;  3UM5 A;  3FS6 A;  3M08 A;  4X5G A;  1RA8 A;  1S3U A;  3F8Z A;  1DG7 A;  3FQV A;  1DYH A;  3OAF A;  3SH2 A;  4QLF A;  3EEL A;  1DG5 A;  3FRB X;  1DRF A;  3LG4 A;  2LF1 A;  4X5F A;  3KFY A;  3QLR A;  3R33 A;  5HVE A;  3SGY A;  3KY8 A;  1VJ3 A;  3FYW X;  3QL0 A;  4DDR A;  1DYJ A;  4OR7 A;  5ECC A;  2CIG A;  4LEK X;  3I3R A;  1RX1 A;  3S7A A;  3JWM A;  5JG0 X;  2C2T A;  2ITH A;  3JWC A;  4P68 A;  4KJK A;  3NU0 A;  1DR4 A;  3E0B A;  4XT4 A;  3K47 A;  2JYB A;  4ELB A;  1DLS A;  4QHV A;  1RX8 A;  2BLA A;  4PDJ A;  3CLB A;  2DHF A;  3GYF A;  3IA5 A;  4M2X A;  2B3Z A;  3FQZ A;  1MVT A;  4NX6 A;  2FZI A;  3JW5 A;  1DLR A;  3K2H A;  2DRC A;  4XT7 A;  3UM6 A;  3NXR A;  4I13 A;  4LAG X;  3IX9 A;  3FQ0 A;  5JA3 A;  2ANQ A;  4EIG A;  1PD9 A;  2O7P A;  3S3V A;  4X5H A;  3RG9 A;  4EIL A;  1KMS A;  4FGH A;  1RA3 A;  5HF2 X;  1RX9 A;  1DR7 A;  1DIS A;  3FY8 X;  1LY3 A;  3CSE A;  4KEB A;  1BOZ A;  4EJ1 A;  4GH8 A;  4H96 A;  4IXE D;  5HF0 X;  3NRR A;  3DAT A;  1HFR A;  4QJZ D;  3SRS X;  1OHK A;  4H97 A;  4XRB A;  5DXV A;  4XT8 A;  4H98 A;  3JWK A;  3SRR X;  1RX3 A;  4LAE X;  3IRO A;  3JW3 A;  4ELF A;  2W9G A;  2W9T A;  3IRM A;  4CD2 A;  3D84 X;  4DP3 A;  1DRA A;  4RGC A;  4G8Z X;  1SEJ A;  1TDR A;  1RF7 A;  5CC9 A;  3N0H A;  3EEM A;  2W3B A;  4M7U A;  3DL5 A;  3KGY A;  1QZF A;  4QLG A;  4KYA A;  4XE6 X;  4QLE A;  3QL3 A;  4DFR A;  1RB2 A;  1S3V A;  1S3W A;  3NZ9 X;  8DFR A;  4ELH A;  1DYR A;  4Q0E A;  3SR5 X;  4KM2 A;  3DL6 A;  2G6V A;  3NZB X;  4PST A;  2H2Q A;  3QFX A;  3EIG A;  4IXF X;  4HOE A;  2QK8 A;  1OHJ A;  3F0X X;  3TD8 A;  3S9U A;  1M7A A;  4KL9 A;  3FYV X;  3K74 A;  3GHW A;  1J3K A;  5HSR A;  5ECX A;  2XW7 A;  2GD9 A;  3NZC X;  3FRD X;  4TU5 X;  4KAK A; 
#chains in the Genus database with same CATH homology
 3DFR A;  1DDR A;  1JUV A;  3SA1 A;  2HM9 A;  1DYI A;  3FQO A;  4I1N A;  4Q0D A;  5U27 A;  1IA2 A;  1D1G A;  1DIU A;  1DDS A;  1JOL A;  1RA2 A;  4G3M A;  5HQY A;  3FQC A;  1CZ3 A;  1DRE A;  3RO9 A;  1HFP A;  4IXG X;  4ELG A;  1AO8 A;  3F0V X;  4QI9 A;  4KBN A;  5HSU A;  4XT5 A;  1DRB A;  2OBC A;  2HXV A;  3GHV A;  3NXO A;  4LAH X;  4PSY A;  4PTH A;  3TQ9 A;  3ZPG A;  3F0U X;  4NX7 A;  3NXT A;  3VCO A;  3QG2 A;  3EX8 A;  3F0S X;  2ANO A;  4Q67 A;  2BLC A;  3L3R A;  1DR5 A;  1U71 A;  5HPB A;  1AI9 A;  1DHF A;  1U70 A;  4P66 A;  4KD7 A;  1DR2 A;  1RB3 A;  1J3I A;  4DPD A;  4X5J A;  1PD8 A;  3HJ3 A;  1AOE A;  4HA7 A;  4QJC A;  1DR3 A;  3EEJ A;  3QGT A;  4M6K A;  2KGK A;  3M09 A;  3DRC A;  4M6J A;  1DG8 A;  3INV A;  4KJL A;  4ELE A;  4HOG A;  1U72 A;  3JTW A;  1IA4 A;  4M7V A;  4KLX A;  3SA2 A;  3SAI A;  3KJR A;  1CD2 A;  1M79 A;  1DRH A;  5CCC A;  3QYO A;  2W9H A;  1ZDR A;  2BLB A;  2FZJ A;  3ZPC A;  1J3J A;  1HFQ A;  1MVS A;  1RX6 A;  5HT4 A;  2ZZA A;  3FRE X;  3SRW X;  3F0B X;  3NXY A;  3TQA A;  3F0Q X;  1M78 A;  4FHB A;  2W3W A;  1S3Y A;  4EIZ A;  3NZ6 X;  1RC4 A;  4OSG A;  3FY9 X;  1RX4 A;  3UM8 A;  4M6L A;  4X5I A;  5HI6 A;  3QLS A;  3IRN A;  3CL9 A;  5HUI A;  2D5N A;  3FRF X;  4KY8 A;  2W3V A;  1BZF A;  4KNE A;  1DR1 A;  3DGA A;  3SRU X;  1RX5 A;  4H95 A;  2L28 A;  2D0K A;  2CD2 A;  1PDB A;  4FGG A;  3ROA A;  1VDR A;  3DAU A;  4XT6 A;  4KY4 A;  3F91 A;  3GI2 A;  5DFR A;  1LUD A;  3QLY A;  2OIP A;  7DFR A;  3FRA X;  1DHI A;  3F8Y A;  4PSS A;  2W3M A;  3FQF A;  5HT5 A;  1RX7 A;  2BL9 A;  3QYL A;  4HA9 A;  5U26 A;  3NZD A;  5FDA A;  3FL8 A;  3I8A X;  1IA3 A;  5HQZ A;  3JVX A;  1DF7 A;  3NXX A;  1RA1 A;  3KJS A;  3QLX A;  2W9S A;  3CD2 A;  3EEK A;  4G95 A;  1LY4 A;  4HOF A;  2FZH A;  1JOM A;  1E26 A;  4DPH A;  3FL9 A;  2AZN A;  3IA4 A;  1RA9 A;  4PTJ A;  3TQB A;  5EAJ A;  4P3Q A;  3NZA X;  2C2S A;  1DAJ A;  3QLZ A;  4KJJ A;  3DG8 A;  3TQ8 A;  1KMV A;  3K45 A;  1RE7 A;  2P4G A;  3JSU A;  4P3R A;  3NXV A;  4KM0 A;  3JWF A;  6DFR A;  3OCH A;  2W3A A;  3SRQ X;  1DR6 A;  4KFJ A;  3HBB A;  1RD7 A;  3GHC A;  1YHO A;  5E8Q A;  1RX2 A;  3NTZ A;  1KLK A;  3D80 A;  2HQP A;  4XEC X;  4ECK A;  1IA1 A;  1DHJ A;  1RG7 A;  2INQ A;  4Q6A A;  3SQY X;  3Q1H A;  5HVB A;  1RH3 A;  3QLW A;  3UM5 A;  3FS6 A;  3M08 A;  4X5G A;  1RA8 A;  1S3U A;  3F8Z A;  1DG7 A;  3FQV A;  1DYH A;  3OAF A;  3SH2 A;  4QLF A;  3EEL A;  1DG5 A;  3FRB X;  1DRF A;  3LG4 A;  2LF1 A;  4X5F A;  3KFY A;  3QLR A;  3R33 A;  5HVE A;  3SGY A;  3KY8 A;  1VJ3 A;  3FYW X;  3QL0 A;  4DDR A;  1DYJ A;  4OR7 A;  5ECC A;  2CIG A;  4LEK X;  3I3R A;  1RX1 A;  3S7A A;  3JWM A;  5JG0 X;  2C2T A;  2ITH A;  3JWC A;  4P68 A;  4KJK A;  3NU0 A;  1DR4 A;  3E0B A;  4XT4 A;  3K47 A;  2JYB A;  4ELB A;  1DLS A;  4QHV A;  1RX8 A;  2BLA A;  4PDJ A;  3CLB A;  2DHF A;  3GYF A;  3IA5 A;  4M2X A;  2B3Z A;  3FQZ A;  1MVT A;  4NX6 A;  2FZI A;  3JW5 A;  1DLR A;  3K2H A;  2DRC A;  4XT7 A;  3UM6 A;  3NXR A;  4I13 A;  4LAG X;  3IX9 A;  3FQ0 A;  5JA3 A;  2ANQ A;  4EIG A;  1PD9 A;  2O7P A;  3S3V A;  4X5H A;  3RG9 A;  4EIL A;  1KMS A;  4FGH A;  1RA3 A;  5HF2 X;  1RX9 A;  1DR7 A;  1DIS A;  3FY8 X;  1LY3 A;  3CSE A;  4KEB A;  1BOZ A;  4EJ1 A;  4GH8 A;  4H96 A;  4IXE D;  5HF0 X;  3NRR A;  3DAT A;  1HFR A;  4QJZ D;  3SRS X;  1OHK A;  4H97 A;  4XRB A;  5DXV A;  4XT8 A;  4H98 A;  3JWK A;  3SRR X;  1RX3 A;  4LAE X;  3IRO A;  3JW3 A;  4ELF A;  2W9G A;  2W9T A;  3IRM A;  4CD2 A;  3D84 X;  4DP3 A;  1DRA A;  4RGC A;  4G8Z X;  1SEJ A;  1TDR A;  1RF7 A;  5CC9 A;  3N0H A;  3EEM A;  2W3B A;  4M7U A;  3DL5 A;  3KGY A;  1QZF A;  4QLG A;  4KYA A;  4XE6 X;  4QLE A;  3QL3 A;  4DFR A;  1RB2 A;  1S3V A;  1S3W A;  3NZ9 X;  8DFR A;  4ELH A;  1DYR A;  4Q0E A;  3SR5 X;  4KM2 A;  3DL6 A;  2G6V A;  3NZB X;  4PST A;  2H2Q A;  3QFX A;  3EIG A;  4IXF X;  4HOE A;  2QK8 A;  1OHJ A;  3F0X X;  3TD8 A;  3S9U A;  1M7A A;  4KL9 A;  3FYV X;  3K74 A;  3GHW A;  1J3K A;  5HSR A;  5ECX A;  2XW7 A;  2GD9 A;  3NZC X;  3FRD X;  4TU5 X;  4KAK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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