4IXFX

Pcdhfr-269 f69n variant
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
206
structure length
206
Chain Sequence
MNQQKSLTLIVALTTSYGIGRSNSLPWKLKKEISYFKRVTSFVPTFDSFESMNVVLMGRKTWESIPLQNRPLKGRINVVITRNESLDLGNGIHSAKSLDHALELLYRTYGSESSVQINRIFVIGGAQLYKAAMDHPKLDRIMATIIYKDIHCDVFFPLKFRDKEWSSVWKKEKHSDLESWVGTKVPHGKINEDGFDYEFEMWTRDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design, Synthesis, and Molecular Modeling of Novel Pyrido[2,3-d]pyrimidine Analogues As Antifolates; Application of Buchwald-Hartwig Aminations of Heterocycles.
pubmed doi rcsb
molecule tags Oxidoreductase/inhibitor
source organism Pneumocystis carinii
molecule keywords Dihydrofolate reductase
total genus 56
structure length 206
sequence length 206
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2013-01-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4ixfX00
3KJSA 3FQVA 4XT7A 3SA1A 3EEKA 3EELA 4H96A 1IA4A 3FQZA 4DP3A 4EIGA 3DFRA 1RD7A 5DFRA 2W9GA 1HFRA 4HA9A 4Q0DA 5EAJA 4QJCA 1TDRA 2D5NA 1S3UA 3S9UA 3TD8A 4X5GA 1DG5A 5HQZA 1HFQA 2BLAA 2INQA 4KNEA 4ELGA 1DR7A 3IRMA 3SH2A 4KL9A 3GI2A 3QL0A 3JW5A 3F0QX 3CSEA 2ZZAA 3KFYA 4OSGA 4XE6X 4IXED 3IX9A 3EX8A 3FY9X 4X5IA 1DDRA 4QLFA 4HOGA 4ELEA 3I8AX 4G95A 4GH8A 3QLZA 3SRRX 4KJLA 4P3QA 2ITHA 2QK8A 4LEKX 1DRHA 3ZPCA 3EEMA 3FY8X 1J3IA 2OBCA 3JVXA 2C2TA 3RG9A 3JSUA 1RC4A 1RX3A 3Q1HA 3UM6A 4P3RA 1JOLA 1RG7A 1CZ3A 4KLXA 2B3ZA 4I13A 1J3KA 3TQAA 4Q6AA 4DPDA 1M78A 1E26A 3FL9A 4PSYA 2CD2A 4ELFA 1BZFA 1U72A 1IA2A 2HXVA 3SRUX 3KGYA 1U71A 1KMVA 5HVEA 4XRBA 1DR2A 4XECX 4LAEX 2L28A 4X5JA 4XT5A 1AI9A 4KM2A 3F91A 3F8ZA 8DFRA 1U70A 1CD2A 2W9SA 1S3WA 1QZFA 5HI6A 2HQPA 2KGKA 4EILA 5HQYA 1IA1A 3M08A 3NXYA 4KD7A 2W9HA 3FS6A 3SR5X 3FQCA 4DDRA 3GHVA 1RA9A 3RO9A 3NZ9X 2W3BA 2W3AA 5U27A 2LF1A 2G6VA 2CIGA 3NZ6X 4Q67A 4H98A 4HOFA 1DG8A 1DR6A 1DHIA 4EJ1A 1DR5A 2DHFA 5HSUA 1OHKA 4QLEA 1PD9A 4NX6A 3SRQX 1LUDA 3GYFA 1SEJA 3F0UX 4Q0EA 5HUIA 3SRSX 3K47A 4KM0A 2ANQA 2P4GA 2XW7A 1DDSA 1HFPA 4XT4A 3R33A 4KJJA 5HVBA 1JUVA 3UM5A 4G3MA 1VJ3A 1JOMA 1DR3A 1J3JA 1RX2A 4NX7A 4KY8A 4FGGA 1KMSA 1OHJA 4RGCA 1DYHA 3QLXA 3CD2A 2BLCA 1RX9A 1ZDRA 4PSSA 1DRAA 5JG0X 4CD2A 3OAFA 2H2QA 1VDRA 4QHVA 4P68A 1IA3A 2W9TA 4ELHA 4TU5X 4LAHX 1S3VA 4FGHA 3CLBA 4PSTA 3D84X 3D80A 3QL3A 4KYAA 4LAGX 4M6LA 4QJZD 2DRCA 3FRFX 1RA3A 1YHOA 3HBBA 1PDBA 3NXVA 3F0XX 1RA2A 3F0BX 4HA7A 3TQ9A 2BLBA 4KEBA 3K2HA 3DG8A 2FZIA 3QG2A 1RE7A 3QGTA 4QLGA 3KY8A 3NZCX 5CCCA 1KLKA 3NRRA 1PD8A 1RF7A 3ZPGA 4ECKA 3GHCA 2OIPA 4M7VA 1RX4A 3QYOA 1MVSA 3FQOA 3SQYX 1DYIA 3EEJA 4I1NA 1DG7A 3JWCA 4X5HA 3QLWA 3KJRA 3FRDX 3TQBA 1DISA 2FZHA 1DIUA 3N0HA 2W3WA 3QFXA 4M6KA 1DHFA 4XT8A 5HF0X 1RB3A 3VCOA 3QLSA 5DXVA 4P66A 3FYWX 2HM9A 3EIGA 1RA1A 3TQ8A 3IA4A 3DRCA 4M6JA 1RX8A 2O7PA 4PDJA 3FQ0A 3K74A 4IXFX 3NXTA 1RB2A 4ELBA 3NZBX 5JA3A 3JWKA 3I3RA 3NXOA 3GHWA 4HOEA 1AOEA 3LG4A 5ECCA 1DF7A 2C2SA 3JWMA 3DGAA 1LY3A 4XT6A 6DFRA 1AO8A 5HF2X 1RH3A 5E8QA 1DRFA 1DR4A 2AZNA 3M09A 3SRWX 1DYRA 3DL6A 3NZAX 4KFJA 4QI9A 3DL5A 1RX7A 3K45A 1DLRA 2JYBA 4PTHA 3IA5A 4DPHA 5CC9A 3NXXA 4X5FA 3FRBX 3UM8A 3NXRA 5U26A 3HJ3A 3IROA 7DFRA 3F0SX 1DHJA 3FREX 4H95A 4OR7A 1LY4A 4KBNA 3L3RA 2GD9A 5HT5A 1DR1A 2FZJA 2BL9A 4DFRA 4KAKA 1DLSA 1D1GA 3QLYA 1RX5A 5HT4A 3OCHA 4KY4A 3JW3A 3JTWA 1S3YA 3FRAX 3S3VA 4M2XA 3S7AA 1M7AA 1MVTA 1DYJA 3FQFA 3CL9A 4M7UA 4FHBA 3DATA 3SAIA 2W3MA 1RA8A 4IXGX 3ROAA 4PTJA 3NTZA 1M79A 3FYVX 3IRNA 3QLRA 3F8YA 1DRBA 5FDAA 4KJKA 4G8ZX 1DREA 2W3VA 3FL8A 3INVA 3SGYA 3JWFA 3DAUA 1BOZA 1RX1A 5HSRA 3NZDA 4EIZA 2D0KA 3NU0A 5HPBA 3F0VX 3E0BA 1RX6A 3QYLA 3SA2A 5ECXA 4H97A 2ANOA 1DAJA
chains in the Genus database with same CATH superfamily
3KJSA 3FQVA 4XT7A 3SA1A 3EEKA 3EELA 4H96A 1IA4A 3FQZA 4DP3A 4EIGA 3DFRA 1RD7A 5DFRA 2W9GA 1HFRA 4HA9A 4Q0DA 5EAJA 4QJCA 1TDRA 2D5NA 1S3UA 3S9UA 3TD8A 4X5GA 1DG5A 5HQZA 1HFQA 2BLAA 2INQA 4KNEA 4ELGA 1DR7A 3IRMA 3SH2A 4KL9A 3GI2A 3QL0A 3JW5A 3F0QX 3CSEA 2ZZAA 3KFYA 4OSGA 4XE6X 4IXED 3IX9A 3EX8A 3FY9X 4X5IA 1DDRA 4QLFA 4HOGA 4ELEA 3I8AX 4G95A 4GH8A 3QLZA 3SRRX 4KJLA 4P3QA 2ITHA 2QK8A 4LEKX 1DRHA 3ZPCA 3EEMA 3FY8X 1J3IA 2OBCA 3JVXA 2C2TA 3RG9A 3JSUA 1RC4A 1RX3A 3Q1HA 3UM6A 4P3RA 1JOLA 1RG7A 1CZ3A 4KLXA 2B3ZA 4I13A 1J3KA 3TQAA 4Q6AA 4DPDA 1M78A 1E26A 3FL9A 4PSYA 2CD2A 4ELFA 1BZFA 1U72A 1IA2A 2HXVA 3SRUX 3KGYA 1U71A 1KMVA 5HVEA 4XRBA 1DR2A 4XECX 4LAEX 2L28A 4X5JA 4XT5A 1AI9A 4KM2A 3F91A 3F8ZA 8DFRA 1U70A 1CD2A 2W9SA 1S3WA 1QZFA 5HI6A 2HQPA 2KGKA 4EILA 5HQYA 1IA1A 3M08A 3NXYA 4KD7A 2W9HA 3FS6A 3SR5X 3FQCA 4DDRA 3GHVA 1RA9A 3RO9A 3NZ9X 2W3BA 2W3AA 5U27A 2LF1A 2G6VA 2CIGA 3NZ6X 4Q67A 4H98A 4HOFA 1DG8A 1DR6A 1DHIA 4EJ1A 1DR5A 2DHFA 5HSUA 1OHKA 4QLEA 1PD9A 4NX6A 3SRQX 1LUDA 3GYFA 1SEJA 3F0UX 4Q0EA 5HUIA 3SRSX 3K47A 4KM0A 2ANQA 2P4GA 2XW7A 1DDSA 1HFPA 4XT4A 3R33A 4KJJA 5HVBA 1JUVA 3UM5A 4G3MA 1VJ3A 1JOMA 1DR3A 1J3JA 1RX2A 4NX7A 4KY8A 4FGGA 1KMSA 1OHJA 4RGCA 1DYHA 3QLXA 3CD2A 2BLCA 1RX9A 1ZDRA 4PSSA 1DRAA 5JG0X 4CD2A 3OAFA 2H2QA 1VDRA 4QHVA 4P68A 1IA3A 2W9TA 4ELHA 4TU5X 4LAHX 1S3VA 4FGHA 3CLBA 4PSTA 3D84X 3D80A 3QL3A 4KYAA 4LAGX 4M6LA 4QJZD 2DRCA 3FRFX 1RA3A 1YHOA 3HBBA 1PDBA 3NXVA 3F0XX 1RA2A 3F0BX 4HA7A 3TQ9A 2BLBA 4KEBA 3K2HA 3DG8A 2FZIA 3QG2A 1RE7A 3QGTA 4QLGA 3KY8A 3NZCX 5CCCA 1KLKA 3NRRA 1PD8A 1RF7A 3ZPGA 4ECKA 3GHCA 2OIPA 4M7VA 1RX4A 3QYOA 1MVSA 3FQOA 3SQYX 1DYIA 3EEJA 4I1NA 1DG7A 3JWCA 4X5HA 3QLWA 3KJRA 3FRDX 3TQBA 1DISA 2FZHA 1DIUA 3N0HA 2W3WA 3QFXA 4M6KA 1DHFA 4XT8A 5HF0X 1RB3A 3VCOA 3QLSA 5DXVA 4P66A 3FYWX 2HM9A 3EIGA 1RA1A 3TQ8A 3IA4A 3DRCA 4M6JA 1RX8A 2O7PA 4PDJA 3FQ0A 3K74A 4IXFX 3NXTA 1RB2A 4ELBA 3NZBX 5JA3A 3JWKA 3I3RA 3NXOA 3GHWA 4HOEA 1AOEA 3LG4A 5ECCA 1DF7A 2C2SA 3JWMA 3DGAA 1LY3A 4XT6A 6DFRA 1AO8A 5HF2X 1RH3A 5E8QA 1DRFA 1DR4A 2AZNA 3M09A 3SRWX 1DYRA 3DL6A 3NZAX 4KFJA 4QI9A 3DL5A 1RX7A 3K45A 1DLRA 2JYBA 4PTHA 3IA5A 4DPHA 5CC9A 3NXXA 4X5FA 3FRBX 3UM8A 3NXRA 5U26A 3HJ3A 3IROA 7DFRA 3F0SX 1DHJA 3FREX 4H95A 4OR7A 1LY4A 4KBNA 3L3RA 2GD9A 5HT5A 1DR1A 2FZJA 2BL9A 4DFRA 4KAKA 1DLSA 1D1GA 3QLYA 1RX5A 5HT4A 3OCHA 4KY4A 3JW3A 3JTWA 1S3YA 3FRAX 3S3VA 4M2XA 3S7AA 1M7AA 1MVTA 1DYJA 3FQFA 3CL9A 4M7UA 4FHBA 3DATA 3SAIA 2W3MA 1RA8A 4IXGX 3ROAA 4PTJA 3NTZA 1M79A 3FYVX 3IRNA 3QLRA 3F8YA 1DRBA 5FDAA 4KJKA 4G8ZX 1DREA 2W3VA 3FL8A 3INVA 3SGYA 3JWFA 3DAUA 1BOZA 1RX1A 5HSRA 3NZDA 4EIZA 2D0KA 3NU0A 5HPBA 3F0VX 3E0BA 1RX6A 3QYLA 3SA2A 5ECXA 4H97A 2ANOA 1DAJA
chains in the Genus database with same CATH topology
3KJSA 3FQVA 4XT7A 3SA1A 3EEKA 3EELA 4H96A 1IA4A 3FQZA 4DP3A 4EIGA 3DFRA 1RD7A 5DFRA 2W9GA 1HFRA 4HA9A 4Q0DA 5EAJA 4QJCA 1TDRA 2D5NA 1S3UA 3S9UA 3TD8A 4X5GA 1DG5A 5HQZA 1HFQA 2BLAA 2INQA 4KNEA 4ELGA 1DR7A 3IRMA 3SH2A 4KL9A 3GI2A 3QL0A 3JW5A 3F0QX 3CSEA 2ZZAA 3KFYA 4OSGA 4XE6X 4IXED 3IX9A 3EX8A 3FY9X 4X5IA 1DDRA 4QLFA 4HOGA 4ELEA 3I8AX 4G95A 4GH8A 3QLZA 3SRRX 4KJLA 4P3QA 2ITHA 2QK8A 4LEKX 1DRHA 3ZPCA 3EEMA 3FY8X 1J3IA 2OBCA 3JVXA 2C2TA 3RG9A 3JSUA 1RC4A 1RX3A 3Q1HA 3UM6A 4P3RA 1JOLA 1RG7A 1CZ3A 4KLXA 2B3ZA 4I13A 1J3KA 3TQAA 4Q6AA 4DPDA 1M78A 1E26A 3FL9A 4PSYA 2CD2A 4ELFA 1BZFA 1U72A 1IA2A 2HXVA 3SRUX 3KGYA 1U71A 1KMVA 5HVEA 4XRBA 1DR2A 4XECX 4LAEX 2L28A 4X5JA 4XT5A 1AI9A 4KM2A 3F91A 3F8ZA 8DFRA 1U70A 1CD2A 2W9SA 1S3WA 1QZFA 5HI6A 2HQPA 2KGKA 4EILA 5HQYA 1IA1A 3M08A 3NXYA 4KD7A 2W9HA 3FS6A 3SR5X 3FQCA 4DDRA 3GHVA 1RA9A 3RO9A 3NZ9X 2W3BA 2W3AA 5U27A 2LF1A 2G6VA 2CIGA 3NZ6X 4Q67A 4H98A 4HOFA 1DG8A 1DR6A 1DHIA 4EJ1A 1DR5A 2DHFA 5HSUA 1OHKA 4QLEA 1PD9A 4NX6A 3SRQX 1LUDA 3GYFA 1SEJA 3F0UX 4Q0EA 5HUIA 3SRSX 3K47A 4KM0A 2ANQA 2P4GA 2XW7A 1DDSA 1HFPA 4XT4A 3R33A 4KJJA 5HVBA 1JUVA 3UM5A 4G3MA 1VJ3A 1JOMA 1DR3A 1J3JA 1RX2A 4NX7A 4KY8A 4FGGA 1KMSA 1OHJA 4RGCA 1DYHA 3QLXA 3CD2A 2BLCA 1RX9A 1ZDRA 4PSSA 1DRAA 5JG0X 4CD2A 3OAFA 2H2QA 1VDRA 4QHVA 4P68A 1IA3A 2W9TA 4ELHA 4TU5X 4LAHX 1S3VA 4FGHA 3CLBA 4PSTA 3D84X 3D80A 3QL3A 4KYAA 4LAGX 4M6LA 4QJZD 2DRCA 3FRFX 1RA3A 1YHOA 3HBBA 1PDBA 3NXVA 3F0XX 1RA2A 3F0BX 4HA7A 3TQ9A 2BLBA 4KEBA 3K2HA 3DG8A 2FZIA 3QG2A 1RE7A 3QGTA 4QLGA 3KY8A 3NZCX 5CCCA 1KLKA 3NRRA 1PD8A 1RF7A 3ZPGA 4ECKA 3GHCA 2OIPA 4M7VA 1RX4A 3QYOA 1MVSA 3FQOA 3SQYX 1DYIA 3EEJA 4I1NA 1DG7A 3JWCA 4X5HA 3QLWA 3KJRA 3FRDX 3TQBA 1DISA 2FZHA 1DIUA 3N0HA 2W3WA 3QFXA 4M6KA 1DHFA 4XT8A 5HF0X 1RB3A 3VCOA 3QLSA 5DXVA 4P66A 3FYWX 2HM9A 3EIGA 1RA1A 3TQ8A 3IA4A 3DRCA 4M6JA 1RX8A 2O7PA 4PDJA 3FQ0A 3K74A 4IXFX 3NXTA 1RB2A 4ELBA 3NZBX 5JA3A 3JWKA 3I3RA 3NXOA 3GHWA 4HOEA 1AOEA 3LG4A 5ECCA 1DF7A 2C2SA 3JWMA 3DGAA 1LY3A 4XT6A 6DFRA 1AO8A 5HF2X 1RH3A 5E8QA 1DRFA 1DR4A 2AZNA 3M09A 3SRWX 1DYRA 3DL6A 3NZAX 4KFJA 4QI9A 3DL5A 1RX7A 3K45A 1DLRA 2JYBA 4PTHA 3IA5A 4DPHA 5CC9A 3NXXA 4X5FA 3FRBX 3UM8A 3NXRA 5U26A 3HJ3A 3IROA 7DFRA 3F0SX 1DHJA 3FREX 4H95A 4OR7A 1LY4A 4KBNA 3L3RA 2GD9A 5HT5A 1DR1A 2FZJA 2BL9A 4DFRA 4KAKA 1DLSA 1D1GA 3QLYA 1RX5A 5HT4A 3OCHA 4KY4A 3JW3A 3JTWA 1S3YA 3FRAX 3S3VA 4M2XA 3S7AA 1M7AA 1MVTA 1DYJA 3FQFA 3CL9A 4M7UA 4FHBA 3DATA 3SAIA 2W3MA 1RA8A 4IXGX 3ROAA 4PTJA 3NTZA 1M79A 3FYVX 3IRNA 3QLRA 3F8YA 1DRBA 5FDAA 4KJKA 4G8ZX 1DREA 2W3VA 3FL8A 3INVA 3SGYA 3JWFA 3DAUA 1BOZA 1RX1A 5HSRA 3NZDA 4EIZA 2D0KA 3NU0A 5HPBA 3F0VX 3E0BA 1RX6A 3QYLA 3SA2A 5ECXA 4H97A 2ANOA 1DAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KJS A;  3FQV A;  4XT7 A;  3SA1 A;  3EEK A;  3EEL A;  4H96 A;  1IA4 A;  3FQZ A;  4DP3 A;  4EIG A;  3DFR A;  1RD7 A;  5DFR A;  2W9G A;  1HFR A;  4HA9 A;  4Q0D A;  5EAJ A;  4QJC A;  1TDR A;  2D5N A;  1S3U A;  3S9U A;  3TD8 A;  4X5G A;  1DG5 A;  5HQZ A;  1HFQ A;  2BLA A;  2INQ A;  4KNE A;  4ELG A;  1DR7 A;  3IRM A;  3SH2 A;  4KL9 A;  3GI2 A;  3QL0 A;  3JW5 A;  3F0Q X;  3CSE A;  2ZZA A;  3KFY A;  4OSG A;  4XE6 X;  4IXE D;  3IX9 A;  3EX8 A;  3FY9 X;  4X5I A;  1DDR A;  4QLF A;  4HOG A;  4ELE A;  3I8A X;  4G95 A;  4GH8 A;  3QLZ A;  3SRR X;  4KJL A;  4P3Q A;  2ITH A;  2QK8 A;  4LEK X;  1DRH A;  3ZPC A;  3EEM A;  3FY8 X;  1J3I A;  2OBC A;  3JVX A;  2C2T A;  3RG9 A;  3JSU A;  1RC4 A;  1RX3 A;  3Q1H A;  3UM6 A;  4P3R A;  1JOL A;  1RG7 A;  1CZ3 A;  4KLX A;  2B3Z A;  4I13 A;  1J3K A;  3TQA A;  4Q6A A;  4DPD A;  1M78 A;  1E26 A;  3FL9 A;  4PSY A;  2CD2 A;  4ELF A;  1BZF A;  1U72 A;  1IA2 A;  2HXV A;  3SRU X;  3KGY A;  1U71 A;  1KMV A;  5HVE A;  4XRB A;  1DR2 A;  4XEC X;  4LAE X;  2L28 A;  4X5J A;  4XT5 A;  1AI9 A;  4KM2 A;  3F91 A;  3F8Z A;  8DFR A;  1U70 A;  1CD2 A;  2W9S A;  1S3W A;  1QZF A;  5HI6 A;  2HQP A;  2KGK A;  4EIL A;  5HQY A;  1IA1 A;  3M08 A;  3NXY A;  4KD7 A;  2W9H A;  3FS6 A;  3SR5 X;  3FQC A;  4DDR A;  3GHV A;  1RA9 A;  3RO9 A;  3NZ9 X;  2W3B A;  2W3A A;  5U27 A;  2LF1 A;  2G6V A;  2CIG A;  3NZ6 X;  4Q67 A;  4H98 A;  4HOF A;  1DG8 A;  1DR6 A;  1DHI A;  4EJ1 A;  1DR5 A;  2DHF A;  5HSU A;  1OHK A;  4QLE A;  1PD9 A;  4NX6 A;  3SRQ X;  1LUD A;  3GYF A;  1SEJ A;  3F0U X;  4Q0E A;  5HUI A;  3SRS X;  3K47 A;  4KM0 A;  2ANQ A;  2P4G A;  2XW7 A;  1DDS A;  1HFP A;  4XT4 A;  3R33 A;  4KJJ A;  5HVB A;  1JUV A;  3UM5 A;  4G3M A;  1VJ3 A;  1JOM A;  1DR3 A;  1J3J A;  1RX2 A;  4NX7 A;  4KY8 A;  4FGG A;  1KMS A;  1OHJ A;  4RGC A;  1DYH A;  3QLX A;  3CD2 A;  2BLC A;  1RX9 A;  1ZDR A;  4PSS A;  1DRA A;  5JG0 X;  4CD2 A;  3OAF A;  2H2Q A;  1VDR A;  4QHV A;  4P68 A;  1IA3 A;  2W9T A;  4ELH A;  4TU5 X;  4LAH X;  1S3V A;  4FGH A;  3CLB A;  4PST A;  3D84 X;  3D80 A;  3QL3 A;  4KYA A;  4LAG X;  4M6L A;  4QJZ D;  2DRC A;  3FRF X;  1RA3 A;  1YHO A;  3HBB A;  1PDB A;  3NXV A;  3F0X X;  1RA2 A;  3F0B X;  4HA7 A;  3TQ9 A;  2BLB A;  4KEB A;  3K2H A;  3DG8 A;  2FZI A;  3QG2 A;  1RE7 A;  3QGT A;  4QLG A;  3KY8 A;  3NZC X;  5CCC A;  1KLK A;  3NRR A;  1PD8 A;  1RF7 A;  3ZPG A;  4ECK A;  3GHC A;  2OIP A;  4M7V A;  1RX4 A;  3QYO A;  1MVS A;  3FQO A;  3SQY X;  1DYI A;  3EEJ A;  4I1N A;  1DG7 A;  3JWC A;  4X5H A;  3QLW A;  3KJR A;  3FRD X;  3TQB A;  1DIS A;  2FZH A;  1DIU A;  3N0H A;  2W3W A;  3QFX A;  4M6K A;  1DHF A;  4XT8 A;  5HF0 X;  1RB3 A;  3VCO A;  3QLS A;  5DXV A;  4P66 A;  3FYW X;  2HM9 A;  3EIG A;  1RA1 A;  3TQ8 A;  3IA4 A;  3DRC A;  4M6J A;  1RX8 A;  2O7P A;  4PDJ A;  3FQ0 A;  3K74 A;  4IXF X;  3NXT A;  1RB2 A;  4ELB A;  3NZB X;  5JA3 A;  3JWK A;  3I3R A;  3NXO A;  3GHW A;  4HOE A;  1AOE A;  3LG4 A;  5ECC A;  1DF7 A;  2C2S A;  3JWM A;  3DGA A;  1LY3 A;  4XT6 A;  6DFR A;  1AO8 A;  5HF2 X;  1RH3 A;  5E8Q A;  1DRF A;  1DR4 A;  2AZN A;  3M09 A;  3SRW X;  1DYR A;  3DL6 A;  3NZA X;  4KFJ A;  4QI9 A;  3DL5 A;  1RX7 A;  3K45 A;  1DLR A;  2JYB A;  4PTH A;  3IA5 A;  4DPH A;  5CC9 A;  3NXX A;  4X5F A;  3FRB X;  3UM8 A;  3NXR A;  5U26 A;  3HJ3 A;  3IRO A;  7DFR A;  3F0S X;  1DHJ A;  3FRE X;  4H95 A;  4OR7 A;  1LY4 A;  4KBN A;  3L3R A;  2GD9 A;  5HT5 A;  1DR1 A;  2FZJ A;  2BL9 A;  4DFR A;  4KAK A;  1DLS A;  1D1G A;  3QLY A;  1RX5 A;  5HT4 A;  3OCH A;  4KY4 A;  3JW3 A;  3JTW A;  1S3Y A;  3FRA X;  3S3V A;  4M2X A;  3S7A A;  1M7A A;  1MVT A;  1DYJ A;  3FQF A;  3CL9 A;  4M7U A;  4FHB A;  3DAT A;  3SAI A;  2W3M A;  1RA8 A;  4IXG X;  3ROA A;  4PTJ A;  3NTZ A;  1M79 A;  3FYV X;  3IRN A;  3QLR A;  3F8Y A;  1DRB A;  5FDA A;  4KJK A;  4G8Z X;  1DRE A;  2W3V A;  3FL8 A;  3INV A;  3SGY A;  3JWF A;  3DAU A;  1BOZ A;  1RX1 A;  5HSR A;  3NZD A;  4EIZ A;  2D0K A;  3NU0 A;  5HPB A;  3F0V X;  3E0B A;  1RX6 A;  3QYL A;  3SA2 A;  5ECX A;  4H97 A;  2ANO A;  1DAJ A; 
#chains in the Genus database with same CATH topology
 3KJS A;  3FQV A;  4XT7 A;  3SA1 A;  3EEK A;  3EEL A;  4H96 A;  1IA4 A;  3FQZ A;  4DP3 A;  4EIG A;  3DFR A;  1RD7 A;  5DFR A;  2W9G A;  1HFR A;  4HA9 A;  4Q0D A;  5EAJ A;  4QJC A;  1TDR A;  2D5N A;  1S3U A;  3S9U A;  3TD8 A;  4X5G A;  1DG5 A;  5HQZ A;  1HFQ A;  2BLA A;  2INQ A;  4KNE A;  4ELG A;  1DR7 A;  3IRM A;  3SH2 A;  4KL9 A;  3GI2 A;  3QL0 A;  3JW5 A;  3F0Q X;  3CSE A;  2ZZA A;  3KFY A;  4OSG A;  4XE6 X;  4IXE D;  3IX9 A;  3EX8 A;  3FY9 X;  4X5I A;  1DDR A;  4QLF A;  4HOG A;  4ELE A;  3I8A X;  4G95 A;  4GH8 A;  3QLZ A;  3SRR X;  4KJL A;  4P3Q A;  2ITH A;  2QK8 A;  4LEK X;  1DRH A;  3ZPC A;  3EEM A;  3FY8 X;  1J3I A;  2OBC A;  3JVX A;  2C2T A;  3RG9 A;  3JSU A;  1RC4 A;  1RX3 A;  3Q1H A;  3UM6 A;  4P3R A;  1JOL A;  1RG7 A;  1CZ3 A;  4KLX A;  2B3Z A;  4I13 A;  1J3K A;  3TQA A;  4Q6A A;  4DPD A;  1M78 A;  1E26 A;  3FL9 A;  4PSY A;  2CD2 A;  4ELF A;  1BZF A;  1U72 A;  1IA2 A;  2HXV A;  3SRU X;  3KGY A;  1U71 A;  1KMV A;  5HVE A;  4XRB A;  1DR2 A;  4XEC X;  4LAE X;  2L28 A;  4X5J A;  4XT5 A;  1AI9 A;  4KM2 A;  3F91 A;  3F8Z A;  8DFR A;  1U70 A;  1CD2 A;  2W9S A;  1S3W A;  1QZF A;  5HI6 A;  2HQP A;  2KGK A;  4EIL A;  5HQY A;  1IA1 A;  3M08 A;  3NXY A;  4KD7 A;  2W9H A;  3FS6 A;  3SR5 X;  3FQC A;  4DDR A;  3GHV A;  1RA9 A;  3RO9 A;  3NZ9 X;  2W3B A;  2W3A A;  5U27 A;  2LF1 A;  2G6V A;  2CIG A;  3NZ6 X;  4Q67 A;  4H98 A;  4HOF A;  1DG8 A;  1DR6 A;  1DHI A;  4EJ1 A;  1DR5 A;  2DHF A;  5HSU A;  1OHK A;  4QLE A;  1PD9 A;  4NX6 A;  3SRQ X;  1LUD A;  3GYF A;  1SEJ A;  3F0U X;  4Q0E A;  5HUI A;  3SRS X;  3K47 A;  4KM0 A;  2ANQ A;  2P4G A;  2XW7 A;  1DDS A;  1HFP A;  4XT4 A;  3R33 A;  4KJJ A;  5HVB A;  1JUV A;  3UM5 A;  4G3M A;  1VJ3 A;  1JOM A;  1DR3 A;  1J3J A;  1RX2 A;  4NX7 A;  4KY8 A;  4FGG A;  1KMS A;  1OHJ A;  4RGC A;  1DYH A;  3QLX A;  3CD2 A;  2BLC A;  1RX9 A;  1ZDR A;  4PSS A;  1DRA A;  5JG0 X;  4CD2 A;  3OAF A;  2H2Q A;  1VDR A;  4QHV A;  4P68 A;  1IA3 A;  2W9T A;  4ELH A;  4TU5 X;  4LAH X;  1S3V A;  4FGH A;  3CLB A;  4PST A;  3D84 X;  3D80 A;  3QL3 A;  4KYA A;  4LAG X;  4M6L A;  4QJZ D;  2DRC A;  3FRF X;  1RA3 A;  1YHO A;  3HBB A;  1PDB A;  3NXV A;  3F0X X;  1RA2 A;  3F0B X;  4HA7 A;  3TQ9 A;  2BLB A;  4KEB A;  3K2H A;  3DG8 A;  2FZI A;  3QG2 A;  1RE7 A;  3QGT A;  4QLG A;  3KY8 A;  3NZC X;  5CCC A;  1KLK A;  3NRR A;  1PD8 A;  1RF7 A;  3ZPG A;  4ECK A;  3GHC A;  2OIP A;  4M7V A;  1RX4 A;  3QYO A;  1MVS A;  3FQO A;  3SQY X;  1DYI A;  3EEJ A;  4I1N A;  1DG7 A;  3JWC A;  4X5H A;  3QLW A;  3KJR A;  3FRD X;  3TQB A;  1DIS A;  2FZH A;  1DIU A;  3N0H A;  2W3W A;  3QFX A;  4M6K A;  1DHF A;  4XT8 A;  5HF0 X;  1RB3 A;  3VCO A;  3QLS A;  5DXV A;  4P66 A;  3FYW X;  2HM9 A;  3EIG A;  1RA1 A;  3TQ8 A;  3IA4 A;  3DRC A;  4M6J A;  1RX8 A;  2O7P A;  4PDJ A;  3FQ0 A;  3K74 A;  4IXF X;  3NXT A;  1RB2 A;  4ELB A;  3NZB X;  5JA3 A;  3JWK A;  3I3R A;  3NXO A;  3GHW A;  4HOE A;  1AOE A;  3LG4 A;  5ECC A;  1DF7 A;  2C2S A;  3JWM A;  3DGA A;  1LY3 A;  4XT6 A;  6DFR A;  1AO8 A;  5HF2 X;  1RH3 A;  5E8Q A;  1DRF A;  1DR4 A;  2AZN A;  3M09 A;  3SRW X;  1DYR A;  3DL6 A;  3NZA X;  4KFJ A;  4QI9 A;  3DL5 A;  1RX7 A;  3K45 A;  1DLR A;  2JYB A;  4PTH A;  3IA5 A;  4DPH A;  5CC9 A;  3NXX A;  4X5F A;  3FRB X;  3UM8 A;  3NXR A;  5U26 A;  3HJ3 A;  3IRO A;  7DFR A;  3F0S X;  1DHJ A;  3FRE X;  4H95 A;  4OR7 A;  1LY4 A;  4KBN A;  3L3R A;  2GD9 A;  5HT5 A;  1DR1 A;  2FZJ A;  2BL9 A;  4DFR A;  4KAK A;  1DLS A;  1D1G A;  3QLY A;  1RX5 A;  5HT4 A;  3OCH A;  4KY4 A;  3JW3 A;  3JTW A;  1S3Y A;  3FRA X;  3S3V A;  4M2X A;  3S7A A;  1M7A A;  1MVT A;  1DYJ A;  3FQF A;  3CL9 A;  4M7U A;  4FHB A;  3DAT A;  3SAI A;  2W3M A;  1RA8 A;  4IXG X;  3ROA A;  4PTJ A;  3NTZ A;  1M79 A;  3FYV X;  3IRN A;  3QLR A;  3F8Y A;  1DRB A;  5FDA A;  4KJK A;  4G8Z X;  1DRE A;  2W3V A;  3FL8 A;  3INV A;  3SGY A;  3JWF A;  3DAU A;  1BOZ A;  1RX1 A;  5HSR A;  3NZD A;  4EIZ A;  2D0K A;  3NU0 A;  5HPB A;  3F0V X;  3E0B A;  1RX6 A;  3QYL A;  3SA2 A;  5ECX A;  4H97 A;  2ANO A;  1DAJ A; 
#chains in the Genus database with same CATH homology
 3KJS A;  3FQV A;  4XT7 A;  3SA1 A;  3EEK A;  3EEL A;  4H96 A;  1IA4 A;  3FQZ A;  4DP3 A;  4EIG A;  3DFR A;  1RD7 A;  5DFR A;  2W9G A;  1HFR A;  4HA9 A;  4Q0D A;  5EAJ A;  4QJC A;  1TDR A;  2D5N A;  1S3U A;  3S9U A;  3TD8 A;  4X5G A;  1DG5 A;  5HQZ A;  1HFQ A;  2BLA A;  2INQ A;  4KNE A;  4ELG A;  1DR7 A;  3IRM A;  3SH2 A;  4KL9 A;  3GI2 A;  3QL0 A;  3JW5 A;  3F0Q X;  3CSE A;  2ZZA A;  3KFY A;  4OSG A;  4XE6 X;  4IXE D;  3IX9 A;  3EX8 A;  3FY9 X;  4X5I A;  1DDR A;  4QLF A;  4HOG A;  4ELE A;  3I8A X;  4G95 A;  4GH8 A;  3QLZ A;  3SRR X;  4KJL A;  4P3Q A;  2ITH A;  2QK8 A;  4LEK X;  1DRH A;  3ZPC A;  3EEM A;  3FY8 X;  1J3I A;  2OBC A;  3JVX A;  2C2T A;  3RG9 A;  3JSU A;  1RC4 A;  1RX3 A;  3Q1H A;  3UM6 A;  4P3R A;  1JOL A;  1RG7 A;  1CZ3 A;  4KLX A;  2B3Z A;  4I13 A;  1J3K A;  3TQA A;  4Q6A A;  4DPD A;  1M78 A;  1E26 A;  3FL9 A;  4PSY A;  2CD2 A;  4ELF A;  1BZF A;  1U72 A;  1IA2 A;  2HXV A;  3SRU X;  3KGY A;  1U71 A;  1KMV A;  5HVE A;  4XRB A;  1DR2 A;  4XEC X;  4LAE X;  2L28 A;  4X5J A;  4XT5 A;  1AI9 A;  4KM2 A;  3F91 A;  3F8Z A;  8DFR A;  1U70 A;  1CD2 A;  2W9S A;  1S3W A;  1QZF A;  5HI6 A;  2HQP A;  2KGK A;  4EIL A;  5HQY A;  1IA1 A;  3M08 A;  3NXY A;  4KD7 A;  2W9H A;  3FS6 A;  3SR5 X;  3FQC A;  4DDR A;  3GHV A;  1RA9 A;  3RO9 A;  3NZ9 X;  2W3B A;  2W3A A;  5U27 A;  2LF1 A;  2G6V A;  2CIG A;  3NZ6 X;  4Q67 A;  4H98 A;  4HOF A;  1DG8 A;  1DR6 A;  1DHI A;  4EJ1 A;  1DR5 A;  2DHF A;  5HSU A;  1OHK A;  4QLE A;  1PD9 A;  4NX6 A;  3SRQ X;  1LUD A;  3GYF A;  1SEJ A;  3F0U X;  4Q0E A;  5HUI A;  3SRS X;  3K47 A;  4KM0 A;  2ANQ A;  2P4G A;  2XW7 A;  1DDS A;  1HFP A;  4XT4 A;  3R33 A;  4KJJ A;  5HVB A;  1JUV A;  3UM5 A;  4G3M A;  1VJ3 A;  1JOM A;  1DR3 A;  1J3J A;  1RX2 A;  4NX7 A;  4KY8 A;  4FGG A;  1KMS A;  1OHJ A;  4RGC A;  1DYH A;  3QLX A;  3CD2 A;  2BLC A;  1RX9 A;  1ZDR A;  4PSS A;  1DRA A;  5JG0 X;  4CD2 A;  3OAF A;  2H2Q A;  1VDR A;  4QHV A;  4P68 A;  1IA3 A;  2W9T A;  4ELH A;  4TU5 X;  4LAH X;  1S3V A;  4FGH A;  3CLB A;  4PST A;  3D84 X;  3D80 A;  3QL3 A;  4KYA A;  4LAG X;  4M6L A;  4QJZ D;  2DRC A;  3FRF X;  1RA3 A;  1YHO A;  3HBB A;  1PDB A;  3NXV A;  3F0X X;  1RA2 A;  3F0B X;  4HA7 A;  3TQ9 A;  2BLB A;  4KEB A;  3K2H A;  3DG8 A;  2FZI A;  3QG2 A;  1RE7 A;  3QGT A;  4QLG A;  3KY8 A;  3NZC X;  5CCC A;  1KLK A;  3NRR A;  1PD8 A;  1RF7 A;  3ZPG A;  4ECK A;  3GHC A;  2OIP A;  4M7V A;  1RX4 A;  3QYO A;  1MVS A;  3FQO A;  3SQY X;  1DYI A;  3EEJ A;  4I1N A;  1DG7 A;  3JWC A;  4X5H A;  3QLW A;  3KJR A;  3FRD X;  3TQB A;  1DIS A;  2FZH A;  1DIU A;  3N0H A;  2W3W A;  3QFX A;  4M6K A;  1DHF A;  4XT8 A;  5HF0 X;  1RB3 A;  3VCO A;  3QLS A;  5DXV A;  4P66 A;  3FYW X;  2HM9 A;  3EIG A;  1RA1 A;  3TQ8 A;  3IA4 A;  3DRC A;  4M6J A;  1RX8 A;  2O7P A;  4PDJ A;  3FQ0 A;  3K74 A;  4IXF X;  3NXT A;  1RB2 A;  4ELB A;  3NZB X;  5JA3 A;  3JWK A;  3I3R A;  3NXO A;  3GHW A;  4HOE A;  1AOE A;  3LG4 A;  5ECC A;  1DF7 A;  2C2S A;  3JWM A;  3DGA A;  1LY3 A;  4XT6 A;  6DFR A;  1AO8 A;  5HF2 X;  1RH3 A;  5E8Q A;  1DRF A;  1DR4 A;  2AZN A;  3M09 A;  3SRW X;  1DYR A;  3DL6 A;  3NZA X;  4KFJ A;  4QI9 A;  3DL5 A;  1RX7 A;  3K45 A;  1DLR A;  2JYB A;  4PTH A;  3IA5 A;  4DPH A;  5CC9 A;  3NXX A;  4X5F A;  3FRB X;  3UM8 A;  3NXR A;  5U26 A;  3HJ3 A;  3IRO A;  7DFR A;  3F0S X;  1DHJ A;  3FRE X;  4H95 A;  4OR7 A;  1LY4 A;  4KBN A;  3L3R A;  2GD9 A;  5HT5 A;  1DR1 A;  2FZJ A;  2BL9 A;  4DFR A;  4KAK A;  1DLS A;  1D1G A;  3QLY A;  1RX5 A;  5HT4 A;  3OCH A;  4KY4 A;  3JW3 A;  3JTW A;  1S3Y A;  3FRA X;  3S3V A;  4M2X A;  3S7A A;  1M7A A;  1MVT A;  1DYJ A;  3FQF A;  3CL9 A;  4M7U A;  4FHB A;  3DAT A;  3SAI A;  2W3M A;  1RA8 A;  4IXG X;  3ROA A;  4PTJ A;  3NTZ A;  1M79 A;  3FYV X;  3IRN A;  3QLR A;  3F8Y A;  1DRB A;  5FDA A;  4KJK A;  4G8Z X;  1DRE A;  2W3V A;  3FL8 A;  3INV A;  3SGY A;  3JWF A;  3DAU A;  1BOZ A;  1RX1 A;  5HSR A;  3NZD A;  4EIZ A;  2D0K A;  3NU0 A;  5HPB A;  3F0V X;  3E0B A;  1RX6 A;  3QYL A;  3SA2 A;  5ECX A;  4H97 A;  2ANO A;  1DAJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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