4JW2B

Selection of specific protein binders for pre-defined targets from an optimized library of artificial helicoidal repeat proteins (alpharep)
Total Genus 73
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
190
structure length
190
Chain Sequence
HHHHTDPEKVEMYIKNLQDDSYYVRRAAAYALGKIGDERAVEPLIKALKDEDAWVRRAAADALGQIGDERAVEPLIKALKDEDGWVRQSAAVALGQIGDERAVEPLIKALKDEDWFVRIAAAFALGEIGDERAVEPLIKALKDEDGWVRQSAADALGEIGGERVRAAMEKLAETGTGFARKVAVNYLETH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep).
pubmed doi rcsb
molecule tags De novo protein/protein binding
source organism Synthetic construct
molecule keywords A3 artificial protein
total genus 73
structure length 190
sequence length 190
ec nomenclature
pdb deposition date 2013-03-27
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.25.10.10 Mainly Alpha Alpha Horseshoe Leucine-rich Repeat Variant Leucine-rich Repeat Variant 4jw2B00
1LRVA 1W63A 3Q0NA 2JKRB 4MFUA 4EVTA 4HNMA 2IWHA 2DB0A 5EKFA 3A6PA 1WA5C 4U5SA 3K61A 4CT7B 4KZGA 2Z5NA 4JLQA 3OUWA 4UWXA 2VGLB 5HHGE 2X1GF 4WV6A 4YJEA 4YI0C 4RXHB 1IBRB 3VE6A 2NYMA 2H4MA 1W63B 1I7XA 4UQIA 5B56A 1IQ1C 1XM9A 3TJZB 4R0ZA 4OO6A 3GB8A 3UL0B 2XA7A 5SWFA 4YK6A 4UADA 3GVTA 3UVUA 3H3DX 3ND2A 3UKYB 5K6SA 4CT6B 2QK1A 4PLRA 1UKLA 2NYMB 4D4EA 5H2XA 3LWWA 3ZINA 4I5LA 4MFVA 1Q1TC 5BZ1A 4I2ZA 3IBVA 1M8WA 4B8OA 1BK6A 3FGAA 4O27A 4ADYA 4A0CA 4U3JC 4EVAA 3QG9A 4I2WA 3WOYA 2Z6HA 4IMJA 4EVPA 1EE4A 1IALA 3Q5UA 2QMRA 5SVZA 4RZPA 3OUXA 3K49A 1M5NS 2PF4A 5KL8A 5J3VA 4OIHA 5KL1A 1JDHA 4K92A 3OQSA 3K5QA 3FEYC 4CV5B 4HTVA 3FGAB 2Z6GA 4PLQA 3WYFC 3ZHPA 3Q0MA 5CTTA 1JPWA 1OYZA 2W3CA 4U5LA 4V3OA 2IE4A 4Y5JA 4JW2B 3O2QA 4CRUB 2QK2A 2JKRA 2RU4A 3WOZA 1U6GC 3TPMA 1UN0A 3ZIPA 2QNAA 4BPLA 4GMOA 3K62A 4FZAA 3OPBA 2YNSA 1B3UA 3NOWA 1M1EA 2IW3A 2F31A 3QHEA 2FV2A 4V3RA 2RU4B 1BK5A 4IMIA 1GCJA 3Q0OA 1UPLA 5KLTB 3ZKVA 1XQSA 3NMXA 4H3HA 3QMLC 3KNDA 2JDQA 1O6OA 3GAEA 4B8JA 3ZIRA 3GVOA 2NYLB 3ODRA 3PSTA 3VWAA 3ZIOA 1Z2CB 3GNIA 3GS3A 2Z5KA 3K5YA 5LSWA 3BCTA 3BTRC 4BQKA 3UL1B 1M8XA 1TH1A 3TX7A 2IX3A 2GL7A 4NEEA 3L3FX 1QBKB 2IE3A 4UAFB 3BX2A 5DN7A 1T08A 5EKGA 3IFQA 4P6ZB 4PLSA 3ZIQA 3EBBA 3QGBA 3UKWB 3K64A 4YJLA 3V6YA 4QMHA 2YNRA 5HUWC 4D49A 4CBAA 3Q0LA 4U5NA 4ZDUA 3O2SA 2Z5OA 1I7WA 3EA5B 5AEIA 3Q0QA 4DJSA 3O2TA 4CRVB 4NZWA 1O6PA 3UKZB 3Q0RA 4U54A 4FFBC 2OF3A 5HUYC 1Q1SC 4U5UA 3TJ3A 3RZXA 3K5ZA 4FZDA 3L6XA 2JKTA 3TT9A 3LTJA 2X19B 3PSPA 4PVZA 1PJNB 4BA3A 4CB8A 5SW9A 3T7UA 3C2GA 5BZVA 1M8ZA 4E4VA 1JPPA 3ODSA 3DW8A 2NYLA 1G3JA 3O4XA 1LUJA 2NPPB 5BZUA 4HXTA 2C1MA 3C5WA 4V3QA 4EV9A 3C2HA 3NMWA 2JKTB 3K7WA 4GMNA 1EJYI 4XZRB 3DADA 2BAPA 5H2WA 5E6QB 1M8YA 4K6JA 1IB2A 3BSXA 4U5OA 1QZ7A 1QGRA 1HO8A 4EV8A 3NMZA 3V71A 4LACA 3FEXC 2IAEA 4L7MA 2P8QA 4FDDA 4DZSA 4R10A 3Q0SA 1V18A 4R11A 4H3KA 4DB6A 3UKXB 2JAKA 4UAEA 2C1TA 1PJMB 4DBAA 1XQRA 5D5KC 2IAEB 2WTKA 4QMIA 3W3UA 1Y2AC 4HM9A 5JJAA 2Q5DA 1F59A 3V74A 3BWTA 4G3AA 3K4EA 4YGXA 5EWPA 3BSBA 3TPOA 1W9CA 4UQIB 3K7VA 3WPTA 3RZ9A 5BZ5A 4DB9A 3LTMA 2BNXA 4FZFA 2XA7B 3L6YA 3L3QA 2Z5MA 1EE5A 5KLRB 4MZ5E 2OT8A 4RV1A 5KLAA 5K9SA 3GQ2A 5BYMA 2BKUB 3BX3A 4DVGB 2BCTA 4P6ZG 2NPPA 4TNMA 4CB9A 3GRLA 4I5NA 4QMJA 5FC8E 3AU3A 1WA5B 4B18A 4U58A 3Q0PA 4MZ6E 1QGKA 3QGCA 2Z5JA 2YJYA 3EG5B 1UPKA 2PKGA 4FQ3A 3OBVA 2VGLA 4U5VA 4DB8A 4B8PA 1EJLI
chains in the Genus database with same CATH superfamily
1LRVA 1W63A 3Q0NA 2JKRB 4MFUA 4EVTA 4HNMA 2IWHA 2DB0A 5EKFA 3A6PA 2XOAA 1WA5C 4U5SA 3K61A 4CT7B 4KZGA 3JXYA 2Z5NA 4JLQA 3OUWA 5CL4A 4UWXA 5CL6A 4I37A 2VGLB 5HHGE 2X1GF 4WV6A 4YJEA 5KUBA 3JY1A 4YI0C 4RXHB 1IBRB 3VE6A 2NYMA 2H4MA 1W63B 1I7XA 4UQIA 5B56A 1IQ1C 1XM9A 3TJZB 4R0ZA 4OO6A 3GB8A 3UL0B 2XA7A 3VLDA 5SWFA 4YK6A 5CLBA 4UADA 3GVTA 3UVUA 3H3DX 3ND2A 3UKYB 5K6SA 4CT6B 2QK1A 4PLRA 1UKLA 2NYMB 4D4EA 5H2XA 3LWWA 3ZINA 4I5LA 4MFVA 1Q1TC 5BZ1A 4I2ZA 3IBVA 1M8WA 4B8OA 1BK6A 3FGAA 4O27A 4ADYA 4A0CA 4U3JC 4EVAA 3QG9A 4I2WA 3WOYA 2Z6HA 4IMJA 4EVPA 1EE4A 1IALA 3Q5UA 2QMRA 5SVZA 4JW2A 4RZPA 3OUXA 3K49A 1M5NS 2PF4A 5KL8A 5J3VA 4OIHA 5CL5A 5KL1A 1JDHA 4K92A 3OQSA 3K5QA 3FEYC 4CV5B 4I0YA 4HTVA 3FGAB 2Z6GA 4PLQA 3WYFC 3ZHPA 3Q0MA 5CTTA 1JPWA 1OYZA 2W3CA 4U5LA 4V3OA 2IE4A 4Y5JA 4JW2B 3O2QA 4CRUB 2QK2A 2JKRA 5CLAA 2RU4A 4U2XD 3WOZA 1U6GC 4L4IA 3TPMA 1LSHA 1UN0A 3ZIPA 2QNAA 4GMOA 4BPLA 3K62A 3SL9A 4FZAA 3OPBA 2YNSA 1B3UA 3NOWA 4FP7A 1M1EA 2IW3A 2F31A 3QHEA 2FV2A 4V3RA 2RU4B 1BK5A 4IMIA 3JXZA 1GCJA 3Q0OA 1UPLA 5KLTB 3ZKVA 4I7IA 1XQSA 3ZILA 3BVSA 3UJ4A 3NMXA 4H3HA 3QMLC 3KNDA 2JDQA 1O6OA 3GAEA 4B8JA 3ZIRA 3GVOA 2NYLB 3ODRA 5CL3A 3PSTA 3UJ0A 3VWAA 3ZIOA 5CL7A 1Z2CB 5CL8A 3GNIA 3GS3A 2Z5KA 4I3NA 3K5YA 5LSWA 3BCTA 3BTRC 4I2SA 4BQKA 3UL1B 4I1EA 1M8XA 1TH1A 3TX7A 2IX3A 2GL7A 4NEEA 3L3FX 1QBKB 2IE3A 4UAFB 3BX2A 4JKQA 5DN7A 1T08A 5EKGA 3IFQA 4P6ZB 4PLSA 3ZIQA 3EBBA 3QGBA 3UKWB 3K64A 4YJLA 3ZIKA 3V6YA 4QMHA 2YNRA 5HUWC 4D49A 4CBAA 3Q0LA 1TE4A 4U5NA 4ZDUA 3O2SA 2Z5OA 1I7WA 3EA5B 5AEIA 3Q0QA 4DJSA 3O2TA 4CRVB 4NZWA 1O6PA 3UKZB 3Q0RA 4U54A 1EJLI 4FFBC 2OF3A 5HUYC 5CLEA 1Q1SC 4U5UA 3TJ3A 3RZXA 3K5ZA 4FZDA 3L6XA 4A3TA 2JKTA 3TT9A 3LTJA 2X19B 3PSPA 4PVZA 1PJNB 4BA3A 4CB8A 5SW9A 4I8MA 3T7UA 3C2GA 5BZVA 1M8ZA 4E4VA 1JPPA 3ODSA 3DW8A 2NYLA 1G3JA 3O4XA 1LUJA 2NPPB 5BZUA 4HXTA 2C1MA 3C5WA 4V3QA 3T8SA 4EV9A 3C2HA 3NMWA 2JKTB 3K7WA 4GMNA 1EJYI 4XZRB 3DADA 5CLDA 2BAPA 5H2WA 5E6QB 1M8YA 4K6JA 1IB2A 3BSXA 4U5OA 1QZ7A 1QGRA 1HO8A 4EV8A 3NMZA 3V71A 4LACA 3FEXC 2IAEA 4L7MA 2P8QA 4FDDA 4DZSA 4L4HA 4R10A 3Q0SA 1V18A 4R11A 4H3KA 4DB6A 4I96A 3UKXB 2JAKA 4UAEA 2C1TA 3VLEA 1PJMB 4DBAA 1XQRA 5D5KC 2IAEB 2WTKA 4QMIA 3W3UA 1Y2AC 4HM9A 5JJAA 2Q5DA 1F59A 3JX7A 3V74A 3BWTA 4G3AA 3K4EA 4YGXA 5EWPA 3BSBA 3TPOA 1W9CA 4UQIB 3K7VA 3WPTA 3RZ9A 5BZ5A 5CL9A 4DB9A 3LTMA 2BNXA 4FZFA 2XA7B 3L6YA 3L3QA 2Z5MA 1EE5A 5KLRB 4MZ5E 2OT8A 3VLFA 4RV1A 5KLAA 5K9SA 3GQ2A 5BYMA 3SLAA 2BKUB 3BX3A 4DVGB 2BCTA 4P6ZG 2NPPA 4TNMA 1N4KA 4CB9A 3GRLA 4I5NA 4QMJA 5FC8E 3AU3A 1WA5B 4B18A 4U58A 3Q0PA 4I6IA 4MZ6E 1QGKA 3QGCA 2Z5JA 2YJYA 3EG5B 1UPKA 2PKGA 4FQ3A 4A3VA 3OBVA 2VGLA 4U5VA 4DB8A 5CLCA 4B8PA 4JW3C
chains in the Genus database with same CATH topology
1LRVA 1W63A 3Q0NA 2JKRB 4MFUA 4EVTA 4HNMA 2IWHA 2DB0A 5EKFA 3A6PA 2XOAA 1WA5C 4U5SA 3K61A 4CT7B 4KZGA 3JXYA 2Z5NA 4JLQA 3OUWA 5CL4A 4UWXA 5CL6A 4I37A 2VGLB 5HHGE 2X1GF 4WV6A 4YJEA 5KUBA 3JY1A 4YI0C 4RXHB 1IBRB 3VE6A 2NYMA 2H4MA 1W63B 1I7XA 4UQIA 5B56A 1IQ1C 1XM9A 3TJZB 4R0ZA 4OO6A 3GB8A 3UL0B 2XA7A 3VLDA 5SWFA 4YK6A 5CLBA 4UADA 3GVTA 3UVUA 3H3DX 3ND2A 3UKYB 5K6SA 4CT6B 2QK1A 4PLRA 1UKLA 2NYMB 4D4EA 5H2XA 3LWWA 3ZINA 4I5LA 4MFVA 1Q1TC 5BZ1A 4I2ZA 3IBVA 1M8WA 4B8OA 1BK6A 3FGAA 4O27A 4ADYA 4A0CA 4U3JC 4EVAA 3QG9A 4I2WA 3WOYA 2Z6HA 4IMJA 4EVPA 1EE4A 1IALA 3Q5UA 2QMRA 5SVZA 4JW2A 4RZPA 3OUXA 3K49A 1M5NS 2PF4A 5KL8A 5J3VA 4OIHA 5CL5A 5KL1A 1JDHA 4K92A 3OQSA 3K5QA 3FEYC 4CV5B 4I0YA 4HTVA 3FGAB 2Z6GA 4PLQA 3WYFC 3ZHPA 3Q0MA 5CTTA 1JPWA 1OYZA 2W3CA 4U5LA 4V3OA 2IE4A 4Y5JA 4JW2B 3O2QA 4CRUB 2QK2A 2JKRA 5CLAA 2RU4A 4U2XD 3WOZA 1U6GC 4L4IA 3TPMA 1UN0A 3ZIPA 2QNAA 4GMOA 4BPLA 3K62A 3SL9A 4FZAA 3OPBA 2YNSA 1B3UA 3NOWA 4FP7A 1M1EA 2IW3A 2F31A 3QHEA 2FV2A 4V3RA 2RU4B 1BK5A 4IMIA 3JXZA 1GCJA 3Q0OA 1UPLA 5KLTB 3ZKVA 4I7IA 1XQSA 3ZILA 3BVSA 3NMXA 4H3HA 3QMLC 3KNDA 2JDQA 1O6OA 3GAEA 4B8JA 3ZIRA 3GVOA 2NYLB 3ODRA 5CL3A 3PSTA 3VWAA 3ZIOA 5CL7A 1Z2CB 5CL8A 3GNIA 3GS3A 2Z5KA 4I3NA 3K5YA 5LSWA 3BCTA 3BTRC 4I2SA 4BQKA 3UL1B 4I1EA 1M8XA 1TH1A 3TX7A 2IX3A 2GL7A 4NEEA 3L3FX 1QBKB 2IE3A 4UAFB 3BX2A 4JKQA 5DN7A 1T08A 5EKGA 3IFQA 4P6ZB 4PLSA 3ZIQA 3EBBA 3QGBA 3UKWB 3K64A 4YJLA 3ZIKA 3V6YA 4QMHA 2YNRA 5HUWC 4D49A 4CBAA 3Q0LA 1TE4A 4U5NA 4ZDUA 3O2SA 2Z5OA 1I7WA 3EA5B 5AEIA 3Q0QA 4DJSA 3O2TA 4CRVB 4NZWA 1O6PA 3UKZB 3Q0RA 4U54A 1EJLI 4FFBC 2OF3A 5HUYC 5CLEA 1Q1SC 4U5UA 3TJ3A 3RZXA 3K5ZA 4FZDA 3L6XA 4A3TA 2JKTA 3TT9A 3LTJA 2X19B 3PSPA 4PVZA 1PJNB 4BA3A 4CB8A 5SW9A 4I8MA 3T7UA 3C2GA 5BZVA 1M8ZA 4E4VA 1JPPA 3ODSA 3DW8A 2NYLA 1G3JA 3O4XA 1LUJA 2NPPB 5BZUA 4HXTA 2C1MA 3C5WA 4V3QA 4EV9A 3C2HA 3NMWA 2JKTB 3K7WA 4GMNA 1EJYI 4XZRB 3DADA 5CLDA 2BAPA 5H2WA 5E6QB 1M8YA 4K6JA 1IB2A 3BSXA 4U5OA 1QZ7A 1QGRA 1HO8A 4EV8A 3NMZA 3V71A 4LACA 3FEXC 2IAEA 4L7MA 2P8QA 4FDDA 4DZSA 4L4HA 4R10A 3Q0SA 1V18A 4R11A 4H3KA 4DB6A 4I96A 3UKXB 2JAKA 4UAEA 2C1TA 3VLEA 1PJMB 4DBAA 1XQRA 5D5KC 2IAEB 2WTKA 4QMIA 3W3UA 1Y2AC 4HM9A 5JJAA 2Q5DA 1F59A 3JX7A 3V74A 3BWTA 4G3AA 3K4EA 4YGXA 5EWPA 3BSBA 3TPOA 1W9CA 4UQIB 3K7VA 3WPTA 3RZ9A 5BZ5A 5CL9A 4DB9A 3LTMA 2BNXA 4FZFA 2XA7B 3L6YA 3L3QA 2Z5MA 1EE5A 5KLRB 4MZ5E 2OT8A 3VLFA 4RV1A 5KLAA 5K9SA 3GQ2A 5BYMA 3SLAA 2BKUB 3BX3A 4DVGB 2BCTA 4P6ZG 2NPPA 4TNMA 4CB9A 3GRLA 4I5NA 4QMJA 5FC8E 3AU3A 1WA5B 4B18A 4U58A 3Q0PA 4I6IA 4MZ6E 1QGKA 3QGCA 2Z5JA 2YJYA 3EG5B 1UPKA 2PKGA 4FQ3A 4A3VA 3OBVA 2VGLA 4U5VA 4DB8A 5CLCA 4B8PA 4JW3C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LRV A;  1W63 A;  3Q0N A;  2JKR B;  4MFU A;  4EVT A;  4HNM A;  2IWH A;  2DB0 A;  5EKF A;  3A6P A;  1WA5 C;  4U5S A;  3K61 A;  4CT7 B;  4KZG A;  2Z5N A;  4JLQ A;  3OUW A;  4UWX A;  2VGL B;  5HHG E;  2X1G F;  4WV6 A;  4YJE A;  4YI0 C;  4RXH B;  1IBR B;  3VE6 A;  2NYM A;  2H4M A;  1W63 B;  1I7X A;  4UQI A;  5B56 A;  1IQ1 C;  1XM9 A;  3TJZ B;  4R0Z A;  4OO6 A;  3GB8 A;  3UL0 B;  2XA7 A;  5SWF A;  4YK6 A;  4UAD A;  3GVT A;  3UVU A;  3H3D X;  3ND2 A;  3UKY B;  5K6S A;  4CT6 B;  2QK1 A;  4PLR A;  1UKL A;  2NYM B;  4D4E A;  5H2X A;  3LWW A;  3ZIN A;  4I5L A;  4MFV A;  1Q1T C;  5BZ1 A;  4I2Z A;  3IBV A;  1M8W A;  4B8O A;  1BK6 A;  3FGA A;  4O27 A;  4ADY A;  4A0C A;  4U3J C;  4EVA A;  3QG9 A;  4I2W A;  3WOY A;  2Z6H A;  4IMJ A;  4EVP A;  1EE4 A;  1IAL A;  3Q5U A;  2QMR A;  5SVZ A;  4RZP A;  3OUX A;  3K49 A;  1M5N S;  2PF4 A;  5KL8 A;  5J3V A;  4OIH A;  5KL1 A;  1JDH A;  4K92 A;  3OQS A;  3K5Q A;  3FEY C;  4CV5 B;  4HTV A;  3FGA B;  2Z6G A;  4PLQ A;  3WYF C;  3ZHP A;  3Q0M A;  5CTT A;  1JPW A;  1OYZ A;  2W3C A;  4U5L A;  4V3O A;  2IE4 A;  4Y5J A;  4JW2 B;  3O2Q A;  4CRU B;  2QK2 A;  2JKR A;  2RU4 A;  3WOZ A;  1U6G C;  3TPM A;  1UN0 A;  3ZIP A;  2QNA A;  4BPL A;  4GMO A;  3K62 A;  4FZA A;  3OPB A;  2YNS A;  1B3U A;  3NOW A;  1M1E A;  2IW3 A;  2F31 A;  3QHE A;  2FV2 A;  4V3R A;  2RU4 B;  1BK5 A;  4IMI A;  1GCJ A;  3Q0O A;  1UPL A;  5KLT B;  3ZKV A;  1XQS A;  3NMX A;  4H3H A;  3QML C;  3KND A;  2JDQ A;  1O6O A;  3GAE A;  4B8J A;  3ZIR A;  3GVO A;  2NYL B;  3ODR A;  3PST A;  3VWA A;  3ZIO A;  1Z2C B;  3GNI A;  3GS3 A;  2Z5K A;  3K5Y A;  5LSW A;  3BCT A;  3BTR C;  4BQK A;  3UL1 B;  1M8X A;  1TH1 A;  3TX7 A;  2IX3 A;  2GL7 A;  4NEE A;  3L3F X;  1QBK B;  2IE3 A;  4UAF B;  3BX2 A;  5DN7 A;  1T08 A;  5EKG A;  3IFQ A;  4P6Z B;  4PLS A;  3ZIQ A;  3EBB A;  3QGB A;  3UKW B;  3K64 A;  4YJL A;  3V6Y A;  4QMH A;  2YNR A;  5HUW C;  4D49 A;  4CBA A;  3Q0L A;  4U5N A;  4ZDU A;  3O2S A;  2Z5O A;  1I7W A;  3EA5 B;  5AEI A;  3Q0Q A;  4DJS A;  3O2T A;  4CRV B;  4NZW A;  1O6P A;  3UKZ B;  3Q0R A;  4U54 A;  4FFB C;  2OF3 A;  5HUY C;  1Q1S C;  4U5U A;  3TJ3 A;  3RZX A;  3K5Z A;  4FZD A;  3L6X A;  2JKT A;  3TT9 A;  3LTJ A;  2X19 B;  3PSP A;  4PVZ A;  1PJN B;  4BA3 A;  4CB8 A;  5SW9 A;  3T7U A;  3C2G A;  5BZV A;  1M8Z A;  4E4V A;  1JPP A;  3ODS A;  3DW8 A;  2NYL A;  1G3J A;  3O4X A;  1LUJ A;  2NPP B;  5BZU A;  4HXT A;  2C1M A;  3C5W A;  4V3Q A;  4EV9 A;  3C2H A;  3NMW A;  2JKT B;  3K7W A;  4GMN A;  1EJY I;  4XZR B;  3DAD A;  2BAP A;  5H2W A;  5E6Q B;  1M8Y A;  4K6J A;  1IB2 A;  3BSX A;  4U5O A;  1QZ7 A;  1QGR A;  1HO8 A;  4EV8 A;  3NMZ A;  3V71 A;  4LAC A;  3FEX C;  2IAE A;  4L7M A;  2P8Q A;  4FDD A;  4DZS A;  4R10 A;  3Q0S A;  1V18 A;  4R11 A;  4H3K A;  4DB6 A;  3UKX B;  2JAK A;  4UAE A;  2C1T A;  1PJM B;  4DBA A;  1XQR A;  5D5K C;  2IAE B;  2WTK A;  4QMI A;  3W3U A;  1Y2A C;  4HM9 A;  5JJA A;  2Q5D A;  1F59 A;  3V74 A;  3BWT A;  4G3A A;  3K4E A;  4YGX A;  5EWP A;  3BSB A;  3TPO A;  1W9C A;  4UQI B;  3K7V A;  3WPT A;  3RZ9 A;  5BZ5 A;  4DB9 A;  3LTM A;  2BNX A;  4FZF A;  2XA7 B;  3L6Y A;  3L3Q A;  2Z5M A;  1EE5 A;  5KLR B;  4MZ5 E;  2OT8 A;  4RV1 A;  5KLA A;  5K9S A;  3GQ2 A;  5BYM A;  2BKU B;  3BX3 A;  4DVG B;  2BCT A;  4P6Z G;  2NPP A;  4TNM A;  4CB9 A;  3GRL A;  4I5N A;  4QMJ A;  5FC8 E;  3AU3 A;  1WA5 B;  4B18 A;  4U58 A;  3Q0P A;  4MZ6 E;  1QGK A;  3QGC A;  2Z5J A;  2YJY A;  3EG5 B;  1UPK A;  2PKG A;  4FQ3 A;  3OBV A;  2VGL A;  4U5V A;  4DB8 A;  4B8P A;  1EJL I; 
#chains in the Genus database with same CATH topology
 1LRV A;  1W63 A;  3Q0N A;  2JKR B;  4MFU A;  4EVT A;  4HNM A;  2IWH A;  2DB0 A;  5EKF A;  3A6P A;  2XOA A;  1WA5 C;  4U5S A;  3K61 A;  4CT7 B;  4KZG A;  3JXY A;  2Z5N A;  4JLQ A;  3OUW A;  5CL4 A;  4UWX A;  5CL6 A;  4I37 A;  2VGL B;  5HHG E;  2X1G F;  4WV6 A;  4YJE A;  5KUB A;  3JY1 A;  4YI0 C;  4RXH B;  1IBR B;  3VE6 A;  2NYM A;  2H4M A;  1W63 B;  1I7X A;  4UQI A;  5B56 A;  1IQ1 C;  1XM9 A;  3TJZ B;  4R0Z A;  4OO6 A;  3GB8 A;  3UL0 B;  2XA7 A;  3VLD A;  5SWF A;  4YK6 A;  5CLB A;  4UAD A;  3GVT A;  3UVU A;  3H3D X;  3ND2 A;  3UKY B;  5K6S A;  4CT6 B;  2QK1 A;  4PLR A;  1UKL A;  2NYM B;  4D4E A;  5H2X A;  3LWW A;  3ZIN A;  4I5L A;  4MFV A;  1Q1T C;  5BZ1 A;  4I2Z A;  3IBV A;  1M8W A;  4B8O A;  1BK6 A;  3FGA A;  4O27 A;  4ADY A;  4A0C A;  4U3J C;  4EVA A;  3QG9 A;  4I2W A;  3WOY A;  2Z6H A;  4IMJ A;  4EVP A;  1EE4 A;  1IAL A;  3Q5U A;  2QMR A;  5SVZ A;  4JW2 A;  4RZP A;  3OUX A;  3K49 A;  1M5N S;  2PF4 A;  5KL8 A;  5J3V A;  4OIH A;  5CL5 A;  5KL1 A;  1JDH A;  4K92 A;  3OQS A;  3K5Q A;  3FEY C;  4CV5 B;  4I0Y A;  4HTV A;  3FGA B;  2Z6G A;  4PLQ A;  3WYF C;  3ZHP A;  3Q0M A;  5CTT A;  1JPW A;  1OYZ A;  2W3C A;  4U5L A;  4V3O A;  2IE4 A;  4Y5J A;  4JW2 B;  3O2Q A;  4CRU B;  2QK2 A;  2JKR A;  5CLA A;  2RU4 A;  4U2X D;  3WOZ A;  1U6G C;  4L4I A;  3TPM A;  1LSH A;  1UN0 A;  3ZIP A;  2QNA A;  4GMO A;  4BPL A;  3K62 A;  3SL9 A;  4FZA A;  3OPB A;  2YNS A;  1B3U A;  3NOW A;  4FP7 A;  1M1E A;  2IW3 A;  2F31 A;  3QHE A;  2FV2 A;  4V3R A;  2RU4 B;  1BK5 A;  4IMI A;  3JXZ A;  1GCJ A;  3Q0O A;  1UPL A;  5KLT B;  3ZKV A;  4I7I A;  1XQS A;  3ZIL A;  3BVS A;  3UJ4 A;  3NMX A;  4H3H A;  3QML C;  3KND A;  2JDQ A;  1O6O A;  3GAE A;  4B8J A;  3ZIR A;  3GVO A;  2NYL B;  3ODR A;  5CL3 A;  3PST A;  3UJ0 A;  3VWA A;  3ZIO A;  5CL7 A;  1Z2C B;  5CL8 A;  3GNI A;  3GS3 A;  2Z5K A;  4I3N A;  3K5Y A;  5LSW A;  3BCT A;  3BTR C;  4I2S A;  4BQK A;  3UL1 B;  4I1E A;  1M8X A;  1TH1 A;  3TX7 A;  2IX3 A;  2GL7 A;  4NEE A;  3L3F X;  1QBK B;  2IE3 A;  4UAF B;  3BX2 A;  4JKQ A;  5DN7 A;  1T08 A;  5EKG A;  3IFQ A;  4P6Z B;  4PLS A;  3ZIQ A;  3EBB A;  3QGB A;  3UKW B;  3K64 A;  4YJL A;  3ZIK A;  3V6Y A;  4QMH A;  2YNR A;  5HUW C;  4D49 A;  4CBA A;  3Q0L A;  1TE4 A;  4U5N A;  4ZDU A;  3O2S A;  2Z5O A;  1I7W A;  3EA5 B;  5AEI A;  3Q0Q A;  4DJS A;  3O2T A;  4CRV B;  4NZW A;  1O6P A;  3UKZ B;  3Q0R A;  4U54 A;  1EJL I;  4FFB C;  2OF3 A;  5HUY C;  5CLE A;  1Q1S C;  4U5U A;  3TJ3 A;  3RZX A;  3K5Z A;  4FZD A;  3L6X A;  4A3T A;  2JKT A;  3TT9 A;  3LTJ A;  2X19 B;  3PSP A;  4PVZ A;  1PJN B;  4BA3 A;  4CB8 A;  5SW9 A;  4I8M A;  3T7U A;  3C2G A;  5BZV A;  1M8Z A;  4E4V A;  1JPP A;  3ODS A;  3DW8 A;  2NYL A;  1G3J A;  3O4X A;  1LUJ A;  2NPP B;  5BZU A;  4HXT A;  2C1M A;  3C5W A;  4V3Q A;  3T8S A;  4EV9 A;  3C2H A;  3NMW A;  2JKT B;  3K7W A;  4GMN A;  1EJY I;  4XZR B;  3DAD A;  5CLD A;  2BAP A;  5H2W A;  5E6Q B;  1M8Y A;  4K6J A;  1IB2 A;  3BSX A;  4U5O A;  1QZ7 A;  1QGR A;  1HO8 A;  4EV8 A;  3NMZ A;  3V71 A;  4LAC A;  3FEX C;  2IAE A;  4L7M A;  2P8Q A;  4FDD A;  4DZS A;  4L4H A;  4R10 A;  3Q0S A;  1V18 A;  4R11 A;  4H3K A;  4DB6 A;  4I96 A;  3UKX B;  2JAK A;  4UAE A;  2C1T A;  3VLE A;  1PJM B;  4DBA A;  1XQR A;  5D5K C;  2IAE B;  2WTK A;  4QMI A;  3W3U A;  1Y2A C;  4HM9 A;  5JJA A;  2Q5D A;  1F59 A;  3JX7 A;  3V74 A;  3BWT A;  4G3A A;  3K4E A;  4YGX A;  5EWP A;  3BSB A;  3TPO A;  1W9C A;  4UQI B;  3K7V A;  3WPT A;  3RZ9 A;  5BZ5 A;  5CL9 A;  4DB9 A;  3LTM A;  2BNX A;  4FZF A;  2XA7 B;  3L6Y A;  3L3Q A;  2Z5M A;  1EE5 A;  5KLR B;  4MZ5 E;  2OT8 A;  3VLF A;  4RV1 A;  5KLA A;  5K9S A;  3GQ2 A;  5BYM A;  3SLA A;  2BKU B;  3BX3 A;  4DVG B;  2BCT A;  4P6Z G;  2NPP A;  4TNM A;  1N4K A;  4CB9 A;  3GRL A;  4I5N A;  4QMJ A;  5FC8 E;  3AU3 A;  1WA5 B;  4B18 A;  4U58 A;  3Q0P A;  4I6I A;  4MZ6 E;  1QGK A;  3QGC A;  2Z5J A;  2YJY A;  3EG5 B;  1UPK A;  2PKG A;  4FQ3 A;  4A3V A;  3OBV A;  2VGL A;  4U5V A;  4DB8 A;  5CLC A;  4B8P A;  4JW3 C; 
#chains in the Genus database with same CATH homology
 1LRV A;  1W63 A;  3Q0N A;  2JKR B;  4MFU A;  4EVT A;  4HNM A;  2IWH A;  2DB0 A;  5EKF A;  3A6P A;  2XOA A;  1WA5 C;  4U5S A;  3K61 A;  4CT7 B;  4KZG A;  3JXY A;  2Z5N A;  4JLQ A;  3OUW A;  5CL4 A;  4UWX A;  5CL6 A;  4I37 A;  2VGL B;  5HHG E;  2X1G F;  4WV6 A;  4YJE A;  5KUB A;  3JY1 A;  4YI0 C;  4RXH B;  1IBR B;  3VE6 A;  2NYM A;  2H4M A;  1W63 B;  1I7X A;  4UQI A;  5B56 A;  1IQ1 C;  1XM9 A;  3TJZ B;  4R0Z A;  4OO6 A;  3GB8 A;  3UL0 B;  2XA7 A;  3VLD A;  5SWF A;  4YK6 A;  5CLB A;  4UAD A;  3GVT A;  3UVU A;  3H3D X;  3ND2 A;  3UKY B;  5K6S A;  4CT6 B;  2QK1 A;  4PLR A;  1UKL A;  2NYM B;  4D4E A;  5H2X A;  3LWW A;  3ZIN A;  4I5L A;  4MFV A;  1Q1T C;  5BZ1 A;  4I2Z A;  3IBV A;  1M8W A;  4B8O A;  1BK6 A;  3FGA A;  4O27 A;  4ADY A;  4A0C A;  4U3J C;  4EVA A;  3QG9 A;  4I2W A;  3WOY A;  2Z6H A;  4IMJ A;  4EVP A;  1EE4 A;  1IAL A;  3Q5U A;  2QMR A;  5SVZ A;  4JW2 A;  4RZP A;  3OUX A;  3K49 A;  1M5N S;  2PF4 A;  5KL8 A;  5J3V A;  4OIH A;  5CL5 A;  5KL1 A;  1JDH A;  4K92 A;  3OQS A;  3K5Q A;  3FEY C;  4CV5 B;  4I0Y A;  4HTV A;  3FGA B;  2Z6G A;  4PLQ A;  3WYF C;  3ZHP A;  3Q0M A;  5CTT A;  1JPW A;  1OYZ A;  2W3C A;  4U5L A;  4V3O A;  2IE4 A;  4Y5J A;  4JW2 B;  3O2Q A;  4CRU B;  2QK2 A;  2JKR A;  5CLA A;  2RU4 A;  4U2X D;  3WOZ A;  1U6G C;  4L4I A;  3TPM A;  1UN0 A;  3ZIP A;  2QNA A;  4GMO A;  4BPL A;  3K62 A;  3SL9 A;  4FZA A;  3OPB A;  2YNS A;  1B3U A;  3NOW A;  4FP7 A;  1M1E A;  2IW3 A;  2F31 A;  3QHE A;  2FV2 A;  4V3R A;  2RU4 B;  1BK5 A;  4IMI A;  3JXZ A;  1GCJ A;  3Q0O A;  1UPL A;  5KLT B;  3ZKV A;  4I7I A;  1XQS A;  3ZIL A;  3BVS A;  3NMX A;  4H3H A;  3QML C;  3KND A;  2JDQ A;  1O6O A;  3GAE A;  4B8J A;  3ZIR A;  3GVO A;  2NYL B;  3ODR A;  5CL3 A;  3PST A;  3VWA A;  3ZIO A;  5CL7 A;  1Z2C B;  5CL8 A;  3GNI A;  3GS3 A;  2Z5K A;  4I3N A;  3K5Y A;  5LSW A;  3BCT A;  3BTR C;  4I2S A;  4BQK A;  3UL1 B;  4I1E A;  1M8X A;  1TH1 A;  3TX7 A;  2IX3 A;  2GL7 A;  4NEE A;  3L3F X;  1QBK B;  2IE3 A;  4UAF B;  3BX2 A;  4JKQ A;  5DN7 A;  1T08 A;  5EKG A;  3IFQ A;  4P6Z B;  4PLS A;  3ZIQ A;  3EBB A;  3QGB A;  3UKW B;  3K64 A;  4YJL A;  3ZIK A;  3V6Y A;  4QMH A;  2YNR A;  5HUW C;  4D49 A;  4CBA A;  3Q0L A;  1TE4 A;  4U5N A;  4ZDU A;  3O2S A;  2Z5O A;  1I7W A;  3EA5 B;  5AEI A;  3Q0Q A;  4DJS A;  3O2T A;  4CRV B;  4NZW A;  1O6P A;  3UKZ B;  3Q0R A;  4U54 A;  1EJL I;  4FFB C;  2OF3 A;  5HUY C;  5CLE A;  1Q1S C;  4U5U A;  3TJ3 A;  3RZX A;  3K5Z A;  4FZD A;  3L6X A;  4A3T A;  2JKT A;  3TT9 A;  3LTJ A;  2X19 B;  3PSP A;  4PVZ A;  1PJN B;  4BA3 A;  4CB8 A;  5SW9 A;  4I8M A;  3T7U A;  3C2G A;  5BZV A;  1M8Z A;  4E4V A;  1JPP A;  3ODS A;  3DW8 A;  2NYL A;  1G3J A;  3O4X A;  1LUJ A;  2NPP B;  5BZU A;  4HXT A;  2C1M A;  3C5W A;  4V3Q A;  4EV9 A;  3C2H A;  3NMW A;  2JKT B;  3K7W A;  4GMN A;  1EJY I;  4XZR B;  3DAD A;  5CLD A;  2BAP A;  5H2W A;  5E6Q B;  1M8Y A;  4K6J A;  1IB2 A;  3BSX A;  4U5O A;  1QZ7 A;  1QGR A;  1HO8 A;  4EV8 A;  3NMZ A;  3V71 A;  4LAC A;  3FEX C;  2IAE A;  4L7M A;  2P8Q A;  4FDD A;  4DZS A;  4L4H A;  4R10 A;  3Q0S A;  1V18 A;  4R11 A;  4H3K A;  4DB6 A;  4I96 A;  3UKX B;  2JAK A;  4UAE A;  2C1T A;  3VLE A;  1PJM B;  4DBA A;  1XQR A;  5D5K C;  2IAE B;  2WTK A;  4QMI A;  3W3U A;  1Y2A C;  4HM9 A;  5JJA A;  2Q5D A;  1F59 A;  3JX7 A;  3V74 A;  3BWT A;  4G3A A;  3K4E A;  4YGX A;  5EWP A;  3BSB A;  3TPO A;  1W9C A;  4UQI B;  3K7V A;  3WPT A;  3RZ9 A;  5BZ5 A;  5CL9 A;  4DB9 A;  3LTM A;  2BNX A;  4FZF A;  2XA7 B;  3L6Y A;  3L3Q A;  2Z5M A;  1EE5 A;  5KLR B;  4MZ5 E;  2OT8 A;  3VLF A;  4RV1 A;  5KLA A;  5K9S A;  3GQ2 A;  5BYM A;  3SLA A;  2BKU B;  3BX3 A;  4DVG B;  2BCT A;  4P6Z G;  2NPP A;  4TNM A;  4CB9 A;  3GRL A;  4I5N A;  4QMJ A;  5FC8 E;  3AU3 A;  1WA5 B;  4B18 A;  4U58 A;  3Q0P A;  4I6I A;  4MZ6 E;  1QGK A;  3QGC A;  2Z5J A;  2YJY A;  3EG5 B;  1UPK A;  2PKG A;  4FQ3 A;  4A3V A;  3OBV A;  2VGL A;  4U5V A;  4DB8 A;  5CLC A;  4B8P A;  4JW3 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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