4KLXA

Crystal structure of dihydrofolate reductase from mycobacterium tuberculosis in an open conformation.
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
161
structure length
161
Chain Sequence
SHMVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mycobacterium tuberculosis Dihydrofolate Reductase Reveals Two Conformational States and a Possible Low Affinity Mechanism to Antifolate Drugs.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mycobacterium tuberculosis
molecule keywords Dihydrofolate reductase
total genus 43
structure length 161
sequence length 161
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2013-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4klxA00
3DRCA 2QK8A 3FQCA 3EIGA 5HVBA 4KAKA 1RH3A 3FQFA 1DYJA 1HFQA 2CD2A 2FZIA 3F0XX 4ECKA 1AOEA 3K74A 3OAFA 4IXGX 1HFRA 3QGTA 3I3RA 2C2SA 1KLKA 3FQVA 4X5HA 4HA7A 3QYOA 5HT4A 3NZDA 1MVTA 4H98A 3KJRA 4IXED 3HJ3A 3FRAX 5U26A 1KMSA 5EAJA 3D80A 3KY8A 4KM0A 4LAHX 1YHOA 4FHBA 3NXYA 3EEKA 3GHVA 3DATA 4LAGX 2W3WA 4H97A 4KYAA 4XE6X 1OHJA 1AI9A 1SEJA 1KMVA 3QLXA 2W9HA 3FL9A 3QLWA 4FGHA 5HSRA 4M7VA 1DIUA 4NX7A 3Q1HA 3CLBA 1DR2A 1IA4A 1TDRA 5HQZA 3UM8A 4M6KA 1PD8A 3JTWA 4P66A 3NZ6X 4M2XA 3FY9X 3KJSA 3SR5X 4DPDA 3N0HA 4CD2A 1ZDRA 3EX8A 5HUIA 1E26A 4G3MA 3K47A 4EIZA 4HOGA 4KEBA 5CC9A 3NXVA 3FYWX 1DRBA 1RB2A 1DR5A 3UM6A 4XT8A 1RA3A 1BZFA 3NRRA 3K45A 5HVEA 8DFRA 1DRAA 3FRFX 4OSGA 4KFJA 4Q67A 3INVA 1RD7A 1JOMA 3EELA 1LUDA 3ZPCA 1DDSA 2W3AA 3QLZA 5HF0X 1RA9A 1DDRA 3JWFA 1LY3A 1RX6A 3F8ZA 2W9GA 3TQBA 1DHIA 3GHCA 3L3RA 3CL9A 2INQA 3NXOA 4KJJA 4M7UA 3SH2A 2DRCA 4XT4A 5HT5A 2FZJA 1DLSA 3R33A 4KY4A 4PTHA 1M7AA 3NZAX 3EEJA 1DR1A 1DYIA 3IRNA 3FRBX 1RX1A 3NZBX 3IX9A 4OR7A 4QLFA 1D1GA 1BOZA 1DISA 4HOEA 3GHWA 2HQPA 2FZHA 5E8QA 1DR3A 2P4GA 4ELGA 4KM2A 1DLRA 4EILA 2ANQA 4KNEA 3FL8A 1IA1A 4PSYA 1DRHA 1M79A 3JSUA 1VDRA 3KFYA 3S9UA 2D0KA 3QL0A 4X5FA 2W3VA 2W9TA 3CD2A 5ECCA 1RA1A 3F8YA 3IA5A 3FQZA 3VCOA 1DG5A 3FS6A 3M09A 1RX3A 3JW3A 2HM9A 1DYRA 3FREX 3SRSX 4H95A 3EEMA 5HSUA 1DYHA 4GH8A 1DF7A 4KJKA 1J3JA 4IXFX 4PSTA 3S7AA 1DG7A 3TQ8A 4Q6AA 3QFXA 3QLRA 1DAJA 4XECX 3K2HA 3RG9A 4QLEA 3GYFA 1QZFA 2BLAA 3TQAA 4ELBA 2G6VA 3DL6A 1PDBA 4P68A 3NU0A 4XT5A 2OIPA 3JW5A 4ELHA 1U70A 3DG8A 1J3IA 5JA3A 1DRFA 3NXRA 3RO9A 3QG2A 3NXTA 3DL5A 4H96A 3F0UX 5ECXA 1HFPA 4FGGA 4I13A 4EIGA 3DGAA 1M78A 1RF7A 4HA9A 4PTJA 3LG4A 1DG8A 3NTZA 1RX2A 2L28A 4KL9A 3I8AX 3FQOA 3F0VX 1RA2A 2XW7A 2AZNA 5HI6A 1U71A 2D5NA 4X5IA 4ELEA 3HBBA 4M6JA 3ZPGA 4G95A 1DR7A 4M6LA 4DPHA 4XT6A 3SRUX 4X5GA 5HQYA 3D84X 1RB3A 1DR6A 2GD9A 2LF1A 2JYBA 4ELFA 1RX9A 5CCCA 1PD9A 4PSSA 3NZCX 3FRDX 2CIGA 3UM5A 3JVXA 5DFRA 1RX8A 1DHJA 3QYLA 4KLXA 1LY4A 2W9SA 3M08A 1J3KA 3DFRA 2ZZAA 1RX7A 4Q0EA 4P3QA 4Q0DA 4QLGA 2OBCA 4QJCA 3JWMA 3QL3A 2C2TA 3FQ0A 1VJ3A 2HXVA 2H2QA 3F0BX 3QLSA 3SRQX 3FYVX 4PDJA 4X5JA 2ITHA 4LEKX 4EJ1A 4TU5X 3TQ9A 1RC4A 1U72A 4P3RA 2W3MA 1IA2A 3JWKA 3DAUA 5HF2X 3F0QX 3SA2A 3NZ9X 2BLCA 1S3WA 1S3YA 1CD2A 3FY8X 1RX5A 4DDRA 2KGKA 4KBNA 4LAEX 4QJZD 2BLBA 7DFRA 1DHFA 1DREA 1S3UA 4DP3A 4KY8A 3SGYA 3SRRX 1RG7A 4G8ZX 3CSEA 3SA1A 1DR4A 5HPBA 3IRMA 4KD7A 2BL9A 4I1NA 3IA4A 5JG0X 3GI2A 2DHFA 3OCHA 3SAIA 1MVSA 1S3VA 4XT7A 4QI9A 5DXVA 1RX4A 6DFRA 4HOFA 3KGYA 3S3VA 4XRBA 1JOLA 3SRWX 4RGCA 4QHVA 1IA3A 2W3BA 1AO8A 1RA8A 3F0SX 4DFRA 1RE7A 3QLYA 2B3ZA 3JWCA 1OHKA 5U27A 2ANOA 1CZ3A 1JUVA 4KJLA 3F91A 2O7PA 5FDAA 3NXXA 3ROAA 3SQYX 4NX6A 3IROA 3TD8A 3E0BA
chains in the Genus database with same CATH superfamily
3DRCA 2QK8A 3FQCA 3EIGA 5HVBA 4KAKA 1RH3A 3FQFA 1DYJA 1HFQA 2CD2A 2FZIA 3F0XX 4ECKA 1AOEA 3K74A 3OAFA 4IXGX 1HFRA 3QGTA 3I3RA 2C2SA 1KLKA 3FQVA 4X5HA 4HA7A 3QYOA 5HT4A 3NZDA 1MVTA 4H98A 3KJRA 4IXED 3HJ3A 3FRAX 5U26A 1KMSA 5EAJA 3D80A 3KY8A 4KM0A 4LAHX 1YHOA 4FHBA 3NXYA 3EEKA 3GHVA 3DATA 4LAGX 2W3WA 4H97A 4KYAA 4XE6X 1OHJA 1AI9A 1SEJA 1KMVA 3QLXA 2W9HA 3FL9A 3QLWA 4FGHA 5HSRA 4M7VA 1DIUA 4NX7A 3Q1HA 3CLBA 1DR2A 1IA4A 1TDRA 5HQZA 3UM8A 4M6KA 1PD8A 3JTWA 4P66A 3NZ6X 4M2XA 3FY9X 3KJSA 3SR5X 4DPDA 3N0HA 4CD2A 1ZDRA 3EX8A 5HUIA 1E26A 4G3MA 3K47A 4EIZA 4HOGA 4KEBA 5CC9A 3NXVA 3FYWX 1DRBA 1RB2A 1DR5A 3UM6A 4XT8A 1RA3A 1BZFA 3NRRA 3K45A 5HVEA 8DFRA 1DRAA 3FRFX 4OSGA 4KFJA 4Q67A 3INVA 1RD7A 1JOMA 3EELA 1LUDA 3ZPCA 1DDSA 2W3AA 3QLZA 5HF0X 1RA9A 1DDRA 3JWFA 1LY3A 1RX6A 3F8ZA 2W9GA 3TQBA 1DHIA 3GHCA 3L3RA 3CL9A 2INQA 3NXOA 4KJJA 4M7UA 3SH2A 2DRCA 4XT4A 5HT5A 2FZJA 1DLSA 3R33A 4KY4A 4PTHA 1M7AA 3NZAX 3EEJA 1DR1A 1DYIA 3IRNA 3FRBX 1RX1A 3NZBX 3IX9A 4OR7A 4QLFA 1D1GA 1BOZA 1DISA 4HOEA 3GHWA 2HQPA 2FZHA 5E8QA 1DR3A 2P4GA 4ELGA 4KM2A 1DLRA 4EILA 2ANQA 4KNEA 3FL8A 1IA1A 4PSYA 1DRHA 1M79A 3JSUA 1VDRA 3KFYA 3S9UA 2D0KA 3QL0A 4X5FA 2W3VA 2W9TA 3CD2A 5ECCA 1RA1A 3F8YA 3IA5A 3FQZA 3VCOA 1DG5A 3FS6A 3M09A 1RX3A 3JW3A 2HM9A 1DYRA 3FREX 3SRSX 4H95A 3EEMA 5HSUA 1DYHA 4GH8A 1DF7A 4KJKA 1J3JA 4IXFX 4PSTA 3S7AA 1DG7A 3TQ8A 4Q6AA 3QFXA 3QLRA 1DAJA 4XECX 3K2HA 3RG9A 4QLEA 3GYFA 1QZFA 2BLAA 3TQAA 4ELBA 2G6VA 3DL6A 1PDBA 4P68A 3NU0A 4XT5A 2OIPA 3JW5A 4ELHA 1U70A 3DG8A 1J3IA 5JA3A 1DRFA 3NXRA 3RO9A 3QG2A 3NXTA 3DL5A 4H96A 3F0UX 5ECXA 1HFPA 4FGGA 4I13A 4EIGA 3DGAA 1M78A 1RF7A 4HA9A 4PTJA 3LG4A 1DG8A 3NTZA 1RX2A 2L28A 4KL9A 3I8AX 3FQOA 3F0VX 1RA2A 2XW7A 2AZNA 5HI6A 1U71A 2D5NA 4X5IA 4ELEA 3HBBA 4M6JA 3ZPGA 4G95A 1DR7A 4M6LA 4DPHA 4XT6A 3SRUX 4X5GA 5HQYA 3D84X 1RB3A 1DR6A 2GD9A 2LF1A 2JYBA 4ELFA 1RX9A 5CCCA 1PD9A 4PSSA 3NZCX 3FRDX 2CIGA 3UM5A 3JVXA 5DFRA 1RX8A 1DHJA 3QYLA 4KLXA 1LY4A 2W9SA 3M08A 1J3KA 3DFRA 2ZZAA 1RX7A 4Q0EA 4P3QA 4Q0DA 4QLGA 2OBCA 4QJCA 3JWMA 3QL3A 2C2TA 3FQ0A 1VJ3A 2HXVA 2H2QA 3F0BX 3QLSA 3SRQX 3FYVX 4PDJA 4X5JA 2ITHA 4LEKX 4EJ1A 4TU5X 3TQ9A 1RC4A 1U72A 4P3RA 2W3MA 1IA2A 3JWKA 3DAUA 5HF2X 3F0QX 3SA2A 3NZ9X 2BLCA 1S3WA 1S3YA 1CD2A 3FY8X 1RX5A 4DDRA 2KGKA 4KBNA 4LAEX 4QJZD 2BLBA 7DFRA 1DHFA 1DREA 1S3UA 4DP3A 4KY8A 3SGYA 3SRRX 1RG7A 4G8ZX 3CSEA 3SA1A 1DR4A 5HPBA 3IRMA 4KD7A 2BL9A 4I1NA 3IA4A 5JG0X 3GI2A 2DHFA 3OCHA 3SAIA 1MVSA 1S3VA 4XT7A 4QI9A 5DXVA 1RX4A 6DFRA 4HOFA 3KGYA 3S3VA 4XRBA 1JOLA 3SRWX 4RGCA 4QHVA 1IA3A 2W3BA 1AO8A 1RA8A 3F0SX 4DFRA 1RE7A 3QLYA 2B3ZA 3JWCA 1OHKA 5U27A 2ANOA 1CZ3A 1JUVA 4KJLA 3F91A 2O7PA 5FDAA 3NXXA 3ROAA 3SQYX 4NX6A 3IROA 3TD8A 3E0BA
chains in the Genus database with same CATH topology
3DRCA 2QK8A 3FQCA 3EIGA 5HVBA 4KAKA 1RH3A 3FQFA 1DYJA 1HFQA 2CD2A 2FZIA 3F0XX 4ECKA 1AOEA 3K74A 3OAFA 4IXGX 1HFRA 3QGTA 3I3RA 2C2SA 1KLKA 3FQVA 4X5HA 4HA7A 3QYOA 5HT4A 3NZDA 1MVTA 4H98A 3KJRA 4IXED 3HJ3A 3FRAX 5U26A 1KMSA 5EAJA 3D80A 3KY8A 4KM0A 4LAHX 1YHOA 4FHBA 3NXYA 3EEKA 3GHVA 3DATA 4LAGX 2W3WA 4H97A 4KYAA 4XE6X 1OHJA 1AI9A 1SEJA 1KMVA 3QLXA 2W9HA 3FL9A 3QLWA 4FGHA 5HSRA 4M7VA 1DIUA 4NX7A 3Q1HA 3CLBA 1DR2A 1IA4A 1TDRA 5HQZA 3UM8A 4M6KA 1PD8A 3JTWA 4P66A 3NZ6X 4M2XA 3FY9X 3KJSA 3SR5X 4DPDA 3N0HA 4CD2A 1ZDRA 3EX8A 5HUIA 1E26A 4G3MA 3K47A 4EIZA 4HOGA 4KEBA 5CC9A 3NXVA 3FYWX 1DRBA 1RB2A 1DR5A 3UM6A 4XT8A 1RA3A 1BZFA 3NRRA 3K45A 5HVEA 8DFRA 1DRAA 3FRFX 4OSGA 4KFJA 4Q67A 3INVA 1RD7A 1JOMA 3EELA 1LUDA 3ZPCA 1DDSA 2W3AA 3QLZA 5HF0X 1RA9A 1DDRA 3JWFA 1LY3A 1RX6A 3F8ZA 2W9GA 3TQBA 1DHIA 3GHCA 3L3RA 3CL9A 2INQA 3NXOA 4KJJA 4M7UA 3SH2A 2DRCA 4XT4A 5HT5A 2FZJA 1DLSA 3R33A 4KY4A 4PTHA 1M7AA 3NZAX 3EEJA 1DR1A 1DYIA 3IRNA 3FRBX 1RX1A 3NZBX 3IX9A 4OR7A 4QLFA 1D1GA 1BOZA 1DISA 4HOEA 3GHWA 2HQPA 2FZHA 5E8QA 1DR3A 2P4GA 4ELGA 4KM2A 1DLRA 4EILA 2ANQA 4KNEA 3FL8A 1IA1A 4PSYA 1DRHA 1M79A 3JSUA 1VDRA 3KFYA 3S9UA 2D0KA 3QL0A 4X5FA 2W3VA 2W9TA 3CD2A 5ECCA 1RA1A 3F8YA 3IA5A 3FQZA 3VCOA 1DG5A 3FS6A 3M09A 1RX3A 3JW3A 2HM9A 1DYRA 3FREX 3SRSX 4H95A 3EEMA 5HSUA 1DYHA 4GH8A 1DF7A 4KJKA 1J3JA 4IXFX 4PSTA 3S7AA 1DG7A 3TQ8A 4Q6AA 3QFXA 3QLRA 1DAJA 4XECX 3K2HA 3RG9A 4QLEA 3GYFA 1QZFA 2BLAA 3TQAA 4ELBA 2G6VA 3DL6A 1PDBA 4P68A 3NU0A 4XT5A 2OIPA 3JW5A 4ELHA 1U70A 3DG8A 1J3IA 5JA3A 1DRFA 3NXRA 3RO9A 3QG2A 3NXTA 3DL5A 4H96A 3F0UX 5ECXA 1HFPA 4FGGA 4I13A 4EIGA 3DGAA 1M78A 1RF7A 4HA9A 4PTJA 3LG4A 1DG8A 3NTZA 1RX2A 2L28A 4KL9A 3I8AX 3FQOA 3F0VX 1RA2A 2XW7A 2AZNA 5HI6A 1U71A 2D5NA 4X5IA 4ELEA 3HBBA 4M6JA 3ZPGA 4G95A 1DR7A 4M6LA 4DPHA 4XT6A 3SRUX 4X5GA 5HQYA 3D84X 1RB3A 1DR6A 2GD9A 2LF1A 2JYBA 4ELFA 1RX9A 5CCCA 1PD9A 4PSSA 3NZCX 3FRDX 2CIGA 3UM5A 3JVXA 5DFRA 1RX8A 1DHJA 3QYLA 4KLXA 1LY4A 2W9SA 3M08A 1J3KA 3DFRA 2ZZAA 1RX7A 4Q0EA 4P3QA 4Q0DA 4QLGA 2OBCA 4QJCA 3JWMA 3QL3A 2C2TA 3FQ0A 1VJ3A 2HXVA 2H2QA 3F0BX 3QLSA 3SRQX 3FYVX 4PDJA 4X5JA 2ITHA 4LEKX 4EJ1A 4TU5X 3TQ9A 1RC4A 1U72A 4P3RA 2W3MA 1IA2A 3JWKA 3DAUA 5HF2X 3F0QX 3SA2A 3NZ9X 2BLCA 1S3WA 1S3YA 1CD2A 3FY8X 1RX5A 4DDRA 2KGKA 4KBNA 4LAEX 4QJZD 2BLBA 7DFRA 1DHFA 1DREA 1S3UA 4DP3A 4KY8A 3SGYA 3SRRX 1RG7A 4G8ZX 3CSEA 3SA1A 1DR4A 5HPBA 3IRMA 4KD7A 2BL9A 4I1NA 3IA4A 5JG0X 3GI2A 2DHFA 3OCHA 3SAIA 1MVSA 1S3VA 4XT7A 4QI9A 5DXVA 1RX4A 6DFRA 4HOFA 3KGYA 3S3VA 4XRBA 1JOLA 3SRWX 4RGCA 4QHVA 1IA3A 2W3BA 1AO8A 1RA8A 3F0SX 4DFRA 1RE7A 3QLYA 2B3ZA 3JWCA 1OHKA 5U27A 2ANOA 1CZ3A 1JUVA 4KJLA 3F91A 2O7PA 5FDAA 3NXXA 3ROAA 3SQYX 4NX6A 3IROA 3TD8A 3E0BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DRC A;  2QK8 A;  3FQC A;  3EIG A;  5HVB A;  4KAK A;  1RH3 A;  3FQF A;  1DYJ A;  1HFQ A;  2CD2 A;  2FZI A;  3F0X X;  4ECK A;  1AOE A;  3K74 A;  3OAF A;  4IXG X;  1HFR A;  3QGT A;  3I3R A;  2C2S A;  1KLK A;  3FQV A;  4X5H A;  4HA7 A;  3QYO A;  5HT4 A;  3NZD A;  1MVT A;  4H98 A;  3KJR A;  4IXE D;  3HJ3 A;  3FRA X;  5U26 A;  1KMS A;  5EAJ A;  3D80 A;  3KY8 A;  4KM0 A;  4LAH X;  1YHO A;  4FHB A;  3NXY A;  3EEK A;  3GHV A;  3DAT A;  4LAG X;  2W3W A;  4H97 A;  4KYA A;  4XE6 X;  1OHJ A;  1AI9 A;  1SEJ A;  1KMV A;  3QLX A;  2W9H A;  3FL9 A;  3QLW A;  4FGH A;  5HSR A;  4M7V A;  1DIU A;  4NX7 A;  3Q1H A;  3CLB A;  1DR2 A;  1IA4 A;  1TDR A;  5HQZ A;  3UM8 A;  4M6K A;  1PD8 A;  3JTW A;  4P66 A;  3NZ6 X;  4M2X A;  3FY9 X;  3KJS A;  3SR5 X;  4DPD A;  3N0H A;  4CD2 A;  1ZDR A;  3EX8 A;  5HUI A;  1E26 A;  4G3M A;  3K47 A;  4EIZ A;  4HOG A;  4KEB A;  5CC9 A;  3NXV A;  3FYW X;  1DRB A;  1RB2 A;  1DR5 A;  3UM6 A;  4XT8 A;  1RA3 A;  1BZF A;  3NRR A;  3K45 A;  5HVE A;  8DFR A;  1DRA A;  3FRF X;  4OSG A;  4KFJ A;  4Q67 A;  3INV A;  1RD7 A;  1JOM A;  3EEL A;  1LUD A;  3ZPC A;  1DDS A;  2W3A A;  3QLZ A;  5HF0 X;  1RA9 A;  1DDR A;  3JWF A;  1LY3 A;  1RX6 A;  3F8Z A;  2W9G A;  3TQB A;  1DHI A;  3GHC A;  3L3R A;  3CL9 A;  2INQ A;  3NXO A;  4KJJ A;  4M7U A;  3SH2 A;  2DRC A;  4XT4 A;  5HT5 A;  2FZJ A;  1DLS A;  3R33 A;  4KY4 A;  4PTH A;  1M7A A;  3NZA X;  3EEJ A;  1DR1 A;  1DYI A;  3IRN A;  3FRB X;  1RX1 A;  3NZB X;  3IX9 A;  4OR7 A;  4QLF A;  1D1G A;  1BOZ A;  1DIS A;  4HOE A;  3GHW A;  2HQP A;  2FZH A;  5E8Q A;  1DR3 A;  2P4G A;  4ELG A;  4KM2 A;  1DLR A;  4EIL A;  2ANQ A;  4KNE A;  3FL8 A;  1IA1 A;  4PSY A;  1DRH A;  1M79 A;  3JSU A;  1VDR A;  3KFY A;  3S9U A;  2D0K A;  3QL0 A;  4X5F A;  2W3V A;  2W9T A;  3CD2 A;  5ECC A;  1RA1 A;  3F8Y A;  3IA5 A;  3FQZ A;  3VCO A;  1DG5 A;  3FS6 A;  3M09 A;  1RX3 A;  3JW3 A;  2HM9 A;  1DYR A;  3FRE X;  3SRS X;  4H95 A;  3EEM A;  5HSU A;  1DYH A;  4GH8 A;  1DF7 A;  4KJK A;  1J3J A;  4IXF X;  4PST A;  3S7A A;  1DG7 A;  3TQ8 A;  4Q6A A;  3QFX A;  3QLR A;  1DAJ A;  4XEC X;  3K2H A;  3RG9 A;  4QLE A;  3GYF A;  1QZF A;  2BLA A;  3TQA A;  4ELB A;  2G6V A;  3DL6 A;  1PDB A;  4P68 A;  3NU0 A;  4XT5 A;  2OIP A;  3JW5 A;  4ELH A;  1U70 A;  3DG8 A;  1J3I A;  5JA3 A;  1DRF A;  3NXR A;  3RO9 A;  3QG2 A;  3NXT A;  3DL5 A;  4H96 A;  3F0U X;  5ECX A;  1HFP A;  4FGG A;  4I13 A;  4EIG A;  3DGA A;  1M78 A;  1RF7 A;  4HA9 A;  4PTJ A;  3LG4 A;  1DG8 A;  3NTZ A;  1RX2 A;  2L28 A;  4KL9 A;  3I8A X;  3FQO A;  3F0V X;  1RA2 A;  2XW7 A;  2AZN A;  5HI6 A;  1U71 A;  2D5N A;  4X5I A;  4ELE A;  3HBB A;  4M6J A;  3ZPG A;  4G95 A;  1DR7 A;  4M6L A;  4DPH A;  4XT6 A;  3SRU X;  4X5G A;  5HQY A;  3D84 X;  1RB3 A;  1DR6 A;  2GD9 A;  2LF1 A;  2JYB A;  4ELF A;  1RX9 A;  5CCC A;  1PD9 A;  4PSS A;  3NZC X;  3FRD X;  2CIG A;  3UM5 A;  3JVX A;  5DFR A;  1RX8 A;  1DHJ A;  3QYL A;  4KLX A;  1LY4 A;  2W9S A;  3M08 A;  1J3K A;  3DFR A;  2ZZA A;  1RX7 A;  4Q0E A;  4P3Q A;  4Q0D A;  4QLG A;  2OBC A;  4QJC A;  3JWM A;  3QL3 A;  2C2T A;  3FQ0 A;  1VJ3 A;  2HXV A;  2H2Q A;  3F0B X;  3QLS A;  3SRQ X;  3FYV X;  4PDJ A;  4X5J A;  2ITH A;  4LEK X;  4EJ1 A;  4TU5 X;  3TQ9 A;  1RC4 A;  1U72 A;  4P3R A;  2W3M A;  1IA2 A;  3JWK A;  3DAU A;  5HF2 X;  3F0Q X;  3SA2 A;  3NZ9 X;  2BLC A;  1S3W A;  1S3Y A;  1CD2 A;  3FY8 X;  1RX5 A;  4DDR A;  2KGK A;  4KBN A;  4LAE X;  4QJZ D;  2BLB A;  7DFR A;  1DHF A;  1DRE A;  1S3U A;  4DP3 A;  4KY8 A;  3SGY A;  3SRR X;  1RG7 A;  4G8Z X;  3CSE A;  3SA1 A;  1DR4 A;  5HPB A;  3IRM A;  4KD7 A;  2BL9 A;  4I1N A;  3IA4 A;  5JG0 X;  3GI2 A;  2DHF A;  3OCH A;  3SAI A;  1MVS A;  1S3V A;  4XT7 A;  4QI9 A;  5DXV A;  1RX4 A;  6DFR A;  4HOF A;  3KGY A;  3S3V A;  4XRB A;  1JOL A;  3SRW X;  4RGC A;  4QHV A;  1IA3 A;  2W3B A;  1AO8 A;  1RA8 A;  3F0S X;  4DFR A;  1RE7 A;  3QLY A;  2B3Z A;  3JWC A;  1OHK A;  5U27 A;  2ANO A;  1CZ3 A;  1JUV A;  4KJL A;  3F91 A;  2O7P A;  5FDA A;  3NXX A;  3ROA A;  3SQY X;  4NX6 A;  3IRO A;  3TD8 A;  3E0B A; 
#chains in the Genus database with same CATH topology
 3DRC A;  2QK8 A;  3FQC A;  3EIG A;  5HVB A;  4KAK A;  1RH3 A;  3FQF A;  1DYJ A;  1HFQ A;  2CD2 A;  2FZI A;  3F0X X;  4ECK A;  1AOE A;  3K74 A;  3OAF A;  4IXG X;  1HFR A;  3QGT A;  3I3R A;  2C2S A;  1KLK A;  3FQV A;  4X5H A;  4HA7 A;  3QYO A;  5HT4 A;  3NZD A;  1MVT A;  4H98 A;  3KJR A;  4IXE D;  3HJ3 A;  3FRA X;  5U26 A;  1KMS A;  5EAJ A;  3D80 A;  3KY8 A;  4KM0 A;  4LAH X;  1YHO A;  4FHB A;  3NXY A;  3EEK A;  3GHV A;  3DAT A;  4LAG X;  2W3W A;  4H97 A;  4KYA A;  4XE6 X;  1OHJ A;  1AI9 A;  1SEJ A;  1KMV A;  3QLX A;  2W9H A;  3FL9 A;  3QLW A;  4FGH A;  5HSR A;  4M7V A;  1DIU A;  4NX7 A;  3Q1H A;  3CLB A;  1DR2 A;  1IA4 A;  1TDR A;  5HQZ A;  3UM8 A;  4M6K A;  1PD8 A;  3JTW A;  4P66 A;  3NZ6 X;  4M2X A;  3FY9 X;  3KJS A;  3SR5 X;  4DPD A;  3N0H A;  4CD2 A;  1ZDR A;  3EX8 A;  5HUI A;  1E26 A;  4G3M A;  3K47 A;  4EIZ A;  4HOG A;  4KEB A;  5CC9 A;  3NXV A;  3FYW X;  1DRB A;  1RB2 A;  1DR5 A;  3UM6 A;  4XT8 A;  1RA3 A;  1BZF A;  3NRR A;  3K45 A;  5HVE A;  8DFR A;  1DRA A;  3FRF X;  4OSG A;  4KFJ A;  4Q67 A;  3INV A;  1RD7 A;  1JOM A;  3EEL A;  1LUD A;  3ZPC A;  1DDS A;  2W3A A;  3QLZ A;  5HF0 X;  1RA9 A;  1DDR A;  3JWF A;  1LY3 A;  1RX6 A;  3F8Z A;  2W9G A;  3TQB A;  1DHI A;  3GHC A;  3L3R A;  3CL9 A;  2INQ A;  3NXO A;  4KJJ A;  4M7U A;  3SH2 A;  2DRC A;  4XT4 A;  5HT5 A;  2FZJ A;  1DLS A;  3R33 A;  4KY4 A;  4PTH A;  1M7A A;  3NZA X;  3EEJ A;  1DR1 A;  1DYI A;  3IRN A;  3FRB X;  1RX1 A;  3NZB X;  3IX9 A;  4OR7 A;  4QLF A;  1D1G A;  1BOZ A;  1DIS A;  4HOE A;  3GHW A;  2HQP A;  2FZH A;  5E8Q A;  1DR3 A;  2P4G A;  4ELG A;  4KM2 A;  1DLR A;  4EIL A;  2ANQ A;  4KNE A;  3FL8 A;  1IA1 A;  4PSY A;  1DRH A;  1M79 A;  3JSU A;  1VDR A;  3KFY A;  3S9U A;  2D0K A;  3QL0 A;  4X5F A;  2W3V A;  2W9T A;  3CD2 A;  5ECC A;  1RA1 A;  3F8Y A;  3IA5 A;  3FQZ A;  3VCO A;  1DG5 A;  3FS6 A;  3M09 A;  1RX3 A;  3JW3 A;  2HM9 A;  1DYR A;  3FRE X;  3SRS X;  4H95 A;  3EEM A;  5HSU A;  1DYH A;  4GH8 A;  1DF7 A;  4KJK A;  1J3J A;  4IXF X;  4PST A;  3S7A A;  1DG7 A;  3TQ8 A;  4Q6A A;  3QFX A;  3QLR A;  1DAJ A;  4XEC X;  3K2H A;  3RG9 A;  4QLE A;  3GYF A;  1QZF A;  2BLA A;  3TQA A;  4ELB A;  2G6V A;  3DL6 A;  1PDB A;  4P68 A;  3NU0 A;  4XT5 A;  2OIP A;  3JW5 A;  4ELH A;  1U70 A;  3DG8 A;  1J3I A;  5JA3 A;  1DRF A;  3NXR A;  3RO9 A;  3QG2 A;  3NXT A;  3DL5 A;  4H96 A;  3F0U X;  5ECX A;  1HFP A;  4FGG A;  4I13 A;  4EIG A;  3DGA A;  1M78 A;  1RF7 A;  4HA9 A;  4PTJ A;  3LG4 A;  1DG8 A;  3NTZ A;  1RX2 A;  2L28 A;  4KL9 A;  3I8A X;  3FQO A;  3F0V X;  1RA2 A;  2XW7 A;  2AZN A;  5HI6 A;  1U71 A;  2D5N A;  4X5I A;  4ELE A;  3HBB A;  4M6J A;  3ZPG A;  4G95 A;  1DR7 A;  4M6L A;  4DPH A;  4XT6 A;  3SRU X;  4X5G A;  5HQY A;  3D84 X;  1RB3 A;  1DR6 A;  2GD9 A;  2LF1 A;  2JYB A;  4ELF A;  1RX9 A;  5CCC A;  1PD9 A;  4PSS A;  3NZC X;  3FRD X;  2CIG A;  3UM5 A;  3JVX A;  5DFR A;  1RX8 A;  1DHJ A;  3QYL A;  4KLX A;  1LY4 A;  2W9S A;  3M08 A;  1J3K A;  3DFR A;  2ZZA A;  1RX7 A;  4Q0E A;  4P3Q A;  4Q0D A;  4QLG A;  2OBC A;  4QJC A;  3JWM A;  3QL3 A;  2C2T A;  3FQ0 A;  1VJ3 A;  2HXV A;  2H2Q A;  3F0B X;  3QLS A;  3SRQ X;  3FYV X;  4PDJ A;  4X5J A;  2ITH A;  4LEK X;  4EJ1 A;  4TU5 X;  3TQ9 A;  1RC4 A;  1U72 A;  4P3R A;  2W3M A;  1IA2 A;  3JWK A;  3DAU A;  5HF2 X;  3F0Q X;  3SA2 A;  3NZ9 X;  2BLC A;  1S3W A;  1S3Y A;  1CD2 A;  3FY8 X;  1RX5 A;  4DDR A;  2KGK A;  4KBN A;  4LAE X;  4QJZ D;  2BLB A;  7DFR A;  1DHF A;  1DRE A;  1S3U A;  4DP3 A;  4KY8 A;  3SGY A;  3SRR X;  1RG7 A;  4G8Z X;  3CSE A;  3SA1 A;  1DR4 A;  5HPB A;  3IRM A;  4KD7 A;  2BL9 A;  4I1N A;  3IA4 A;  5JG0 X;  3GI2 A;  2DHF A;  3OCH A;  3SAI A;  1MVS A;  1S3V A;  4XT7 A;  4QI9 A;  5DXV A;  1RX4 A;  6DFR A;  4HOF A;  3KGY A;  3S3V A;  4XRB A;  1JOL A;  3SRW X;  4RGC A;  4QHV A;  1IA3 A;  2W3B A;  1AO8 A;  1RA8 A;  3F0S X;  4DFR A;  1RE7 A;  3QLY A;  2B3Z A;  3JWC A;  1OHK A;  5U27 A;  2ANO A;  1CZ3 A;  1JUV A;  4KJL A;  3F91 A;  2O7P A;  5FDA A;  3NXX A;  3ROA A;  3SQY X;  4NX6 A;  3IRO A;  3TD8 A;  3E0B A; 
#chains in the Genus database with same CATH homology
 3DRC A;  2QK8 A;  3FQC A;  3EIG A;  5HVB A;  4KAK A;  1RH3 A;  3FQF A;  1DYJ A;  1HFQ A;  2CD2 A;  2FZI A;  3F0X X;  4ECK A;  1AOE A;  3K74 A;  3OAF A;  4IXG X;  1HFR A;  3QGT A;  3I3R A;  2C2S A;  1KLK A;  3FQV A;  4X5H A;  4HA7 A;  3QYO A;  5HT4 A;  3NZD A;  1MVT A;  4H98 A;  3KJR A;  4IXE D;  3HJ3 A;  3FRA X;  5U26 A;  1KMS A;  5EAJ A;  3D80 A;  3KY8 A;  4KM0 A;  4LAH X;  1YHO A;  4FHB A;  3NXY A;  3EEK A;  3GHV A;  3DAT A;  4LAG X;  2W3W A;  4H97 A;  4KYA A;  4XE6 X;  1OHJ A;  1AI9 A;  1SEJ A;  1KMV A;  3QLX A;  2W9H A;  3FL9 A;  3QLW A;  4FGH A;  5HSR A;  4M7V A;  1DIU A;  4NX7 A;  3Q1H A;  3CLB A;  1DR2 A;  1IA4 A;  1TDR A;  5HQZ A;  3UM8 A;  4M6K A;  1PD8 A;  3JTW A;  4P66 A;  3NZ6 X;  4M2X A;  3FY9 X;  3KJS A;  3SR5 X;  4DPD A;  3N0H A;  4CD2 A;  1ZDR A;  3EX8 A;  5HUI A;  1E26 A;  4G3M A;  3K47 A;  4EIZ A;  4HOG A;  4KEB A;  5CC9 A;  3NXV A;  3FYW X;  1DRB A;  1RB2 A;  1DR5 A;  3UM6 A;  4XT8 A;  1RA3 A;  1BZF A;  3NRR A;  3K45 A;  5HVE A;  8DFR A;  1DRA A;  3FRF X;  4OSG A;  4KFJ A;  4Q67 A;  3INV A;  1RD7 A;  1JOM A;  3EEL A;  1LUD A;  3ZPC A;  1DDS A;  2W3A A;  3QLZ A;  5HF0 X;  1RA9 A;  1DDR A;  3JWF A;  1LY3 A;  1RX6 A;  3F8Z A;  2W9G A;  3TQB A;  1DHI A;  3GHC A;  3L3R A;  3CL9 A;  2INQ A;  3NXO A;  4KJJ A;  4M7U A;  3SH2 A;  2DRC A;  4XT4 A;  5HT5 A;  2FZJ A;  1DLS A;  3R33 A;  4KY4 A;  4PTH A;  1M7A A;  3NZA X;  3EEJ A;  1DR1 A;  1DYI A;  3IRN A;  3FRB X;  1RX1 A;  3NZB X;  3IX9 A;  4OR7 A;  4QLF A;  1D1G A;  1BOZ A;  1DIS A;  4HOE A;  3GHW A;  2HQP A;  2FZH A;  5E8Q A;  1DR3 A;  2P4G A;  4ELG A;  4KM2 A;  1DLR A;  4EIL A;  2ANQ A;  4KNE A;  3FL8 A;  1IA1 A;  4PSY A;  1DRH A;  1M79 A;  3JSU A;  1VDR A;  3KFY A;  3S9U A;  2D0K A;  3QL0 A;  4X5F A;  2W3V A;  2W9T A;  3CD2 A;  5ECC A;  1RA1 A;  3F8Y A;  3IA5 A;  3FQZ A;  3VCO A;  1DG5 A;  3FS6 A;  3M09 A;  1RX3 A;  3JW3 A;  2HM9 A;  1DYR A;  3FRE X;  3SRS X;  4H95 A;  3EEM A;  5HSU A;  1DYH A;  4GH8 A;  1DF7 A;  4KJK A;  1J3J A;  4IXF X;  4PST A;  3S7A A;  1DG7 A;  3TQ8 A;  4Q6A A;  3QFX A;  3QLR A;  1DAJ A;  4XEC X;  3K2H A;  3RG9 A;  4QLE A;  3GYF A;  1QZF A;  2BLA A;  3TQA A;  4ELB A;  2G6V A;  3DL6 A;  1PDB A;  4P68 A;  3NU0 A;  4XT5 A;  2OIP A;  3JW5 A;  4ELH A;  1U70 A;  3DG8 A;  1J3I A;  5JA3 A;  1DRF A;  3NXR A;  3RO9 A;  3QG2 A;  3NXT A;  3DL5 A;  4H96 A;  3F0U X;  5ECX A;  1HFP A;  4FGG A;  4I13 A;  4EIG A;  3DGA A;  1M78 A;  1RF7 A;  4HA9 A;  4PTJ A;  3LG4 A;  1DG8 A;  3NTZ A;  1RX2 A;  2L28 A;  4KL9 A;  3I8A X;  3FQO A;  3F0V X;  1RA2 A;  2XW7 A;  2AZN A;  5HI6 A;  1U71 A;  2D5N A;  4X5I A;  4ELE A;  3HBB A;  4M6J A;  3ZPG A;  4G95 A;  1DR7 A;  4M6L A;  4DPH A;  4XT6 A;  3SRU X;  4X5G A;  5HQY A;  3D84 X;  1RB3 A;  1DR6 A;  2GD9 A;  2LF1 A;  2JYB A;  4ELF A;  1RX9 A;  5CCC A;  1PD9 A;  4PSS A;  3NZC X;  3FRD X;  2CIG A;  3UM5 A;  3JVX A;  5DFR A;  1RX8 A;  1DHJ A;  3QYL A;  4KLX A;  1LY4 A;  2W9S A;  3M08 A;  1J3K A;  3DFR A;  2ZZA A;  1RX7 A;  4Q0E A;  4P3Q A;  4Q0D A;  4QLG A;  2OBC A;  4QJC A;  3JWM A;  3QL3 A;  2C2T A;  3FQ0 A;  1VJ3 A;  2HXV A;  2H2Q A;  3F0B X;  3QLS A;  3SRQ X;  3FYV X;  4PDJ A;  4X5J A;  2ITH A;  4LEK X;  4EJ1 A;  4TU5 X;  3TQ9 A;  1RC4 A;  1U72 A;  4P3R A;  2W3M A;  1IA2 A;  3JWK A;  3DAU A;  5HF2 X;  3F0Q X;  3SA2 A;  3NZ9 X;  2BLC A;  1S3W A;  1S3Y A;  1CD2 A;  3FY8 X;  1RX5 A;  4DDR A;  2KGK A;  4KBN A;  4LAE X;  4QJZ D;  2BLB A;  7DFR A;  1DHF A;  1DRE A;  1S3U A;  4DP3 A;  4KY8 A;  3SGY A;  3SRR X;  1RG7 A;  4G8Z X;  3CSE A;  3SA1 A;  1DR4 A;  5HPB A;  3IRM A;  4KD7 A;  2BL9 A;  4I1N A;  3IA4 A;  5JG0 X;  3GI2 A;  2DHF A;  3OCH A;  3SAI A;  1MVS A;  1S3V A;  4XT7 A;  4QI9 A;  5DXV A;  1RX4 A;  6DFR A;  4HOF A;  3KGY A;  3S3V A;  4XRB A;  1JOL A;  3SRW X;  4RGC A;  4QHV A;  1IA3 A;  2W3B A;  1AO8 A;  1RA8 A;  3F0S X;  4DFR A;  1RE7 A;  3QLY A;  2B3Z A;  3JWC A;  1OHK A;  5U27 A;  2ANO A;  1CZ3 A;  1JUV A;  4KJL A;  3F91 A;  2O7P A;  5FDA A;  3NXX A;  3ROA A;  3SQY X;  4NX6 A;  3IRO A;  3TD8 A;  3E0B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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