4OR7A

Klebsiella pneumoniae dihydrofolate reductase complexed with nadph and 6-ethyl-5-{3-[3-(pyrimidin-5-yl)phenyl]prop-1-yn-1-yl}pyrimidine-2,4-diamine
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
165
structure length
165
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGRLTWESIGRPLPGRKNIVISSKPGSDDRVQWVSSVEEAIAACGDVEEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYDPDEWESVFSEFHDADAQNSHSYCFEILERRHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Klebsiella pneumoniae Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal Features for Potency and Selectivity.
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Klebsiella pneumoniae cg43
molecule keywords Dihydrofolate reductase
total genus 45
structure length 165
sequence length 165
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-02-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4or7A00
4KM0A 4QLEA 1PDBA 2FZIA 4OSGA 3NZ9X 1DRBA 3SRQX 4Q0EA 4X5GA 4KBNA 2DHFA 3F0BX 3JVXA 3F0VX 3IA5A 4ELBA 1HFPA 4I13A 3EEKA 3RG9A 3NZAX 3UM8A 3QLZA 3DAUA 4LEKX 3FRDX 2W9HA 5HUIA 3TD8A 3QLWA 3TQ9A 3LG4A 3UM5A 3QL3A 3FQVA 4EILA 4IXED 3JWCA 3NZBX 3QLYA 2KGKA 3FL8A 3K47A 3NRRA 3S7AA 3DFRA 2BLCA 4HOFA 4HA9A 3IRNA 1DRHA 2CIGA 3EEJA 2W9SA 4DPHA 3QG2A 3EELA 4KAKA 3ZPCA 5HF0X 1DYHA 2JYBA 4KL9A 1LY4A 4QLGA 1M7AA 1DREA 4X5HA 4KJLA 3SQYX 3FRFX 1DR4A 3FY9X 4FGHA 4EJ1A 3NXRA 1VJ3A 4G3MA 2B3ZA 4PTHA 1DRFA 5DFRA 3SAIA 3F0SX 3OCHA 2QK8A 3FYWX 4LAGX 4P66A 4CD2A 5E8QA 1LY3A 1J3IA 4H95A 1RX8A 3QLSA 3FRBX 2ZZAA 3NZCX 3KGYA 4KY4A 5JA3A 3FQ0A 1JOMA 4XRBA 1DDSA 1JOLA 3DRCA 1AI9A 3F0UX 1U70A 1S3YA 3F91A 3VCOA 1PD9A 1S3VA 3QLXA 4ELEA 3JSUA 4NX7A 2ITHA 1DR5A 1RG7A 3OAFA 3M08A 3HJ3A 3M09A 1D1GA 1M78A 3K2HA 1DR2A 4QJCA 1MVTA 3FQZA 2OBCA 5HI6A 1RX5A 2GD9A 3QYLA 1IA4A 3CLBA 1RH3A 2BLBA 1J3KA 4H97A 3CL9A 1VDRA 3GHVA 1RX4A 4XT6A 2HXVA 3SH2A 3NXXA 1DHIA 1OHKA 3TQBA 3F8ZA 1RD7A 4OR7A 1CD2A 3IROA 3K45A 5HQYA 1DR6A 3N0HA 3NXTA 4M6JA 1QZFA 2D5NA 4QI9A 4EIZA 3D84X 3NXYA 1DR3A 4XECX 2AZNA 3F8YA 1DYRA 2HQPA 3F0QX 2ANOA 5ECXA 2G6VA 3SRRX 3QL0A 3SR5X 1AOEA 1TDRA 4KFJA 3TQ8A 4FGGA 5DXVA 4XT7A 4ELFA 3Q1HA 2W9TA 5U27A 3K74A 3CD2A 4FHBA 5HT4A 1RA1A 3ROAA 3QGTA 1IA1A 3DATA 2INQA 2W3WA 3DL5A 3NZDA 2BLAA 4KNEA 2W3VA 1RX7A 3I8AX 4PSYA 3D80A 3E0BA 3NXOA 1SEJA 4RGCA 4XE6X 3R33A 1DR7A 1U71A 2P4GA 4LAEX 3FQOA 4H96A 3EX8A 1KLKA 3FREX 5HF2X 1DISA 5HSUA 3JWMA 3KJSA 3FQCA 4P68A 3F0XX 1RA3A 4KM2A 3TQAA 4M6LA 4KJKA 3IA4A 3NU0A 4IXFX 3KY8A 1E26A 3S9UA 1DHJA 1YHOA 4P3QA 3IRMA 4HA7A 5EAJA 5FDAA 5CCCA 4Q0DA 4KLXA 4KEBA 1OHJA 1MVSA 3UM6A 2H2QA 2D0KA 2CD2A 2ANQA 4X5JA 3SRUX 3QLRA 3QYOA 5JG0X 1DLSA 2C2SA 4ELHA 2L28A 3GYFA 1DG5A 1ZDRA 7DFRA 1DYIA 5HPBA 4PSSA 1RX1A 1PD8A 4PDJA 1AO8A 3JW5A 3NXVA 4TU5X 4KYAA 1BZFA 3JWKA 3GHCA 1RX2A 3FS6A 1DG8A 3KFYA 3RO9A 1HFQA 1IA3A 3INVA 2OIPA 1RA9A 1DG7A 2W3BA 5ECCA 3IX9A 2LF1A 1BOZA 4LAHX 5HT5A 6DFRA 1DIUA 1S3WA 4IXGX 3GI2A 4KJJA 3DG8A 3DL6A 3I3RA 5CC9A 4DP3A 1U72A 1RC4A 4QHVA 3SA2A 4ECKA 3FRAX 3FL9A 1IA2A 2FZHA 3FQFA 4DPDA 1DR1A 8DFRA 4PTJA 3L3RA 3HBBA 4H98A 2DRCA 2HM9A 2FZJA 4GH8A 1RX9A 4Q67A 2W3AA 1CZ3A 3NZ6X 1S3UA 4HOEA 3JTWA 4M6KA 4ELGA 4P3RA 4DFRA 2BL9A 1HFRA 3QFXA 1DRAA 3EEMA 1RB3A 1DF7A 3GHWA 1RA8A 3JW3A 3SA1A 3SRWX 4M7VA 1DDRA 3S3VA 4XT4A 1M79A 3NTZA 3SRSX 3EIGA 2W9GA 4X5FA 1RX6A 1DHFA 2W3MA 1RX3A 3DGAA 3KJRA 1DLRA 4G95A 3CSEA 3ZPGA 1RB2A 1LUDA 4M2XA 4KY8A 2XW7A 4I1NA 4NX6A 3FYVX 3FY8X 1JUVA 4X5IA 1KMVA 5U26A 2C2TA 4HOGA 4Q6AA 4PSTA 3SGYA 4XT5A 1RF7A 4QLFA 4G8ZX 1DAJA 5HSRA 5HQZA 4M7UA 4XT8A 5HVBA 1DYJA 2O7PA 1KMSA 1RE7A 4EIGA 1RA2A 1J3JA 3JWFA 4KD7A 5HVEA 4DDRA 4QJZD
chains in the Genus database with same CATH superfamily
4KM0A 4QLEA 1PDBA 2FZIA 4OSGA 3NZ9X 1DRBA 3SRQX 4Q0EA 4X5GA 4KBNA 2DHFA 3F0BX 3JVXA 3F0VX 3IA5A 4ELBA 1HFPA 4I13A 3EEKA 3RG9A 3NZAX 3UM8A 3QLZA 3DAUA 4LEKX 3FRDX 2W9HA 5HUIA 3TD8A 3QLWA 3TQ9A 3LG4A 3UM5A 3QL3A 3FQVA 4EILA 4IXED 3JWCA 3NZBX 3QLYA 2KGKA 3FL8A 3K47A 3NRRA 3S7AA 3DFRA 2BLCA 4HOFA 4HA9A 3IRNA 1DRHA 2CIGA 3EEJA 2W9SA 4DPHA 3QG2A 3EELA 4KAKA 3ZPCA 5HF0X 1DYHA 2JYBA 4KL9A 1LY4A 4QLGA 1M7AA 1DREA 4X5HA 4KJLA 3SQYX 3FRFX 1DR4A 3FY9X 4FGHA 4EJ1A 3NXRA 1VJ3A 4G3MA 2B3ZA 4PTHA 1DRFA 5DFRA 3SAIA 3F0SX 3OCHA 2QK8A 3FYWX 4LAGX 4P66A 4CD2A 5E8QA 1LY3A 1J3IA 4H95A 1RX8A 3QLSA 3FRBX 2ZZAA 3NZCX 3KGYA 4KY4A 5JA3A 3FQ0A 1JOMA 4XRBA 1DDSA 1JOLA 3DRCA 1AI9A 3F0UX 1U70A 1S3YA 3F91A 3VCOA 1PD9A 1S3VA 3QLXA 4ELEA 3JSUA 4NX7A 2ITHA 1DR5A 1RG7A 3OAFA 3M08A 3HJ3A 3M09A 1D1GA 1M78A 3K2HA 1DR2A 4QJCA 1MVTA 3FQZA 2OBCA 5HI6A 1RX5A 2GD9A 3QYLA 1IA4A 3CLBA 1RH3A 2BLBA 1J3KA 4H97A 3CL9A 1VDRA 3GHVA 1RX4A 4XT6A 2HXVA 3SH2A 3NXXA 1DHIA 1OHKA 3TQBA 3F8ZA 1RD7A 4OR7A 1CD2A 3IROA 3K45A 5HQYA 1DR6A 3N0HA 3NXTA 4M6JA 1QZFA 2D5NA 4QI9A 4EIZA 3D84X 3NXYA 1DR3A 4XECX 2AZNA 3F8YA 1DYRA 2HQPA 3F0QX 2ANOA 5ECXA 2G6VA 3SRRX 3QL0A 3SR5X 1AOEA 1TDRA 4KFJA 3TQ8A 4FGGA 5DXVA 4XT7A 4ELFA 3Q1HA 2W9TA 5U27A 3K74A 3CD2A 4FHBA 5HT4A 1RA1A 3ROAA 3QGTA 1IA1A 3DATA 2INQA 2W3WA 3DL5A 3NZDA 2BLAA 4KNEA 2W3VA 1RX7A 3I8AX 4PSYA 3D80A 3E0BA 3NXOA 1SEJA 4RGCA 4XE6X 3R33A 1DR7A 1U71A 2P4GA 4LAEX 3FQOA 4H96A 3EX8A 1KLKA 3FREX 5HF2X 1DISA 5HSUA 3JWMA 3KJSA 3FQCA 4P68A 3F0XX 1RA3A 4KM2A 3TQAA 4M6LA 4KJKA 3IA4A 3NU0A 4IXFX 3KY8A 1E26A 3S9UA 1DHJA 1YHOA 4P3QA 3IRMA 4HA7A 5EAJA 5FDAA 5CCCA 4Q0DA 4KLXA 4KEBA 1OHJA 1MVSA 3UM6A 2H2QA 2D0KA 2CD2A 2ANQA 4X5JA 3SRUX 3QLRA 3QYOA 5JG0X 1DLSA 2C2SA 4ELHA 2L28A 3GYFA 1DG5A 1ZDRA 7DFRA 1DYIA 5HPBA 4PSSA 1RX1A 1PD8A 4PDJA 1AO8A 3JW5A 3NXVA 4TU5X 4KYAA 1BZFA 3JWKA 3GHCA 1RX2A 3FS6A 1DG8A 3KFYA 3RO9A 1HFQA 1IA3A 3INVA 2OIPA 1RA9A 1DG7A 2W3BA 5ECCA 3IX9A 2LF1A 1BOZA 4LAHX 5HT5A 6DFRA 1DIUA 1S3WA 4IXGX 3GI2A 4KJJA 3DG8A 3DL6A 3I3RA 5CC9A 4DP3A 1U72A 1RC4A 4QHVA 3SA2A 4ECKA 3FRAX 3FL9A 1IA2A 2FZHA 3FQFA 4DPDA 1DR1A 8DFRA 4PTJA 3L3RA 3HBBA 4H98A 2DRCA 2HM9A 2FZJA 4GH8A 1RX9A 4Q67A 2W3AA 1CZ3A 3NZ6X 1S3UA 4HOEA 3JTWA 4M6KA 4ELGA 4P3RA 4DFRA 2BL9A 1HFRA 3QFXA 1DRAA 3EEMA 1RB3A 1DF7A 3GHWA 1RA8A 3JW3A 3SA1A 3SRWX 4M7VA 1DDRA 3S3VA 4XT4A 1M79A 3NTZA 3SRSX 3EIGA 2W9GA 4X5FA 1RX6A 1DHFA 2W3MA 1RX3A 3DGAA 3KJRA 1DLRA 4G95A 3CSEA 3ZPGA 1RB2A 1LUDA 4M2XA 4KY8A 2XW7A 4I1NA 4NX6A 3FYVX 3FY8X 1JUVA 4X5IA 1KMVA 5U26A 2C2TA 4HOGA 4Q6AA 4PSTA 3SGYA 4XT5A 1RF7A 4QLFA 4G8ZX 1DAJA 5HSRA 5HQZA 4M7UA 4XT8A 5HVBA 1DYJA 2O7PA 1KMSA 1RE7A 4EIGA 1RA2A 1J3JA 3JWFA 4KD7A 5HVEA 4DDRA 4QJZD
chains in the Genus database with same CATH topology
4KM0A 4QLEA 1PDBA 2FZIA 4OSGA 3NZ9X 1DRBA 3SRQX 4Q0EA 4X5GA 4KBNA 2DHFA 3F0BX 3JVXA 3F0VX 3IA5A 4ELBA 1HFPA 4I13A 3EEKA 3RG9A 3NZAX 3UM8A 3QLZA 3DAUA 4LEKX 3FRDX 2W9HA 5HUIA 3TD8A 3QLWA 3TQ9A 3LG4A 3UM5A 3QL3A 3FQVA 4EILA 4IXED 3JWCA 3NZBX 3QLYA 2KGKA 3FL8A 3K47A 3NRRA 3S7AA 3DFRA 2BLCA 4HOFA 4HA9A 3IRNA 1DRHA 2CIGA 3EEJA 2W9SA 4DPHA 3QG2A 3EELA 4KAKA 3ZPCA 5HF0X 1DYHA 2JYBA 4KL9A 1LY4A 4QLGA 1M7AA 1DREA 4X5HA 4KJLA 3SQYX 3FRFX 1DR4A 3FY9X 4FGHA 4EJ1A 3NXRA 1VJ3A 4G3MA 2B3ZA 4PTHA 1DRFA 5DFRA 3SAIA 3F0SX 3OCHA 2QK8A 3FYWX 4LAGX 4P66A 4CD2A 5E8QA 1LY3A 1J3IA 4H95A 1RX8A 3QLSA 3FRBX 2ZZAA 3NZCX 3KGYA 4KY4A 5JA3A 3FQ0A 1JOMA 4XRBA 1DDSA 1JOLA 3DRCA 1AI9A 3F0UX 1U70A 1S3YA 3F91A 3VCOA 1PD9A 1S3VA 3QLXA 4ELEA 3JSUA 4NX7A 2ITHA 1DR5A 1RG7A 3OAFA 3M08A 3HJ3A 3M09A 1D1GA 1M78A 3K2HA 1DR2A 4QJCA 1MVTA 3FQZA 2OBCA 5HI6A 1RX5A 2GD9A 3QYLA 1IA4A 3CLBA 1RH3A 2BLBA 1J3KA 4H97A 3CL9A 1VDRA 3GHVA 1RX4A 4XT6A 2HXVA 3SH2A 3NXXA 1DHIA 1OHKA 3TQBA 3F8ZA 1RD7A 4OR7A 1CD2A 3IROA 3K45A 5HQYA 1DR6A 3N0HA 3NXTA 4M6JA 1QZFA 2D5NA 4QI9A 4EIZA 3D84X 3NXYA 1DR3A 4XECX 2AZNA 3F8YA 1DYRA 2HQPA 3F0QX 2ANOA 5ECXA 2G6VA 3SRRX 3QL0A 3SR5X 1AOEA 1TDRA 4KFJA 3TQ8A 4FGGA 5DXVA 4XT7A 4ELFA 3Q1HA 2W9TA 5U27A 3K74A 3CD2A 4FHBA 5HT4A 1RA1A 3ROAA 3QGTA 1IA1A 3DATA 2INQA 2W3WA 3DL5A 3NZDA 2BLAA 4KNEA 2W3VA 1RX7A 3I8AX 4PSYA 3D80A 3E0BA 3NXOA 1SEJA 4RGCA 4XE6X 3R33A 1DR7A 1U71A 2P4GA 4LAEX 3FQOA 4H96A 3EX8A 1KLKA 3FREX 5HF2X 1DISA 5HSUA 3JWMA 3KJSA 3FQCA 4P68A 3F0XX 1RA3A 4KM2A 3TQAA 4M6LA 4KJKA 3IA4A 3NU0A 4IXFX 3KY8A 1E26A 3S9UA 1DHJA 1YHOA 4P3QA 3IRMA 4HA7A 5EAJA 5FDAA 5CCCA 4Q0DA 4KLXA 4KEBA 1OHJA 1MVSA 3UM6A 2H2QA 2D0KA 2CD2A 2ANQA 4X5JA 3SRUX 3QLRA 3QYOA 5JG0X 1DLSA 2C2SA 4ELHA 2L28A 3GYFA 1DG5A 1ZDRA 7DFRA 1DYIA 5HPBA 4PSSA 1RX1A 1PD8A 4PDJA 1AO8A 3JW5A 3NXVA 4TU5X 4KYAA 1BZFA 3JWKA 3GHCA 1RX2A 3FS6A 1DG8A 3KFYA 3RO9A 1HFQA 1IA3A 3INVA 2OIPA 1RA9A 1DG7A 2W3BA 5ECCA 3IX9A 2LF1A 1BOZA 4LAHX 5HT5A 6DFRA 1DIUA 1S3WA 4IXGX 3GI2A 4KJJA 3DG8A 3DL6A 3I3RA 5CC9A 4DP3A 1U72A 1RC4A 4QHVA 3SA2A 4ECKA 3FRAX 3FL9A 1IA2A 2FZHA 3FQFA 4DPDA 1DR1A 8DFRA 4PTJA 3L3RA 3HBBA 4H98A 2DRCA 2HM9A 2FZJA 4GH8A 1RX9A 4Q67A 2W3AA 1CZ3A 3NZ6X 1S3UA 4HOEA 3JTWA 4M6KA 4ELGA 4P3RA 4DFRA 2BL9A 1HFRA 3QFXA 1DRAA 3EEMA 1RB3A 1DF7A 3GHWA 1RA8A 3JW3A 3SA1A 3SRWX 4M7VA 1DDRA 3S3VA 4XT4A 1M79A 3NTZA 3SRSX 3EIGA 2W9GA 4X5FA 1RX6A 1DHFA 2W3MA 1RX3A 3DGAA 3KJRA 1DLRA 4G95A 3CSEA 3ZPGA 1RB2A 1LUDA 4M2XA 4KY8A 2XW7A 4I1NA 4NX6A 3FYVX 3FY8X 1JUVA 4X5IA 1KMVA 5U26A 2C2TA 4HOGA 4Q6AA 4PSTA 3SGYA 4XT5A 1RF7A 4QLFA 4G8ZX 1DAJA 5HSRA 5HQZA 4M7UA 4XT8A 5HVBA 1DYJA 2O7PA 1KMSA 1RE7A 4EIGA 1RA2A 1J3JA 3JWFA 4KD7A 5HVEA 4DDRA 4QJZD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KM0 A;  4QLE A;  1PDB A;  2FZI A;  4OSG A;  3NZ9 X;  1DRB A;  3SRQ X;  4Q0E A;  4X5G A;  4KBN A;  2DHF A;  3F0B X;  3JVX A;  3F0V X;  3IA5 A;  4ELB A;  1HFP A;  4I13 A;  3EEK A;  3RG9 A;  3NZA X;  3UM8 A;  3QLZ A;  3DAU A;  4LEK X;  3FRD X;  2W9H A;  5HUI A;  3TD8 A;  3QLW A;  3TQ9 A;  3LG4 A;  3UM5 A;  3QL3 A;  3FQV A;  4EIL A;  4IXE D;  3JWC A;  3NZB X;  3QLY A;  2KGK A;  3FL8 A;  3K47 A;  3NRR A;  3S7A A;  3DFR A;  2BLC A;  4HOF A;  4HA9 A;  3IRN A;  1DRH A;  2CIG A;  3EEJ A;  2W9S A;  4DPH A;  3QG2 A;  3EEL A;  4KAK A;  3ZPC A;  5HF0 X;  1DYH A;  2JYB A;  4KL9 A;  1LY4 A;  4QLG A;  1M7A A;  1DRE A;  4X5H A;  4KJL A;  3SQY X;  3FRF X;  1DR4 A;  3FY9 X;  4FGH A;  4EJ1 A;  3NXR A;  1VJ3 A;  4G3M A;  2B3Z A;  4PTH A;  1DRF A;  5DFR A;  3SAI A;  3F0S X;  3OCH A;  2QK8 A;  3FYW X;  4LAG X;  4P66 A;  4CD2 A;  5E8Q A;  1LY3 A;  1J3I A;  4H95 A;  1RX8 A;  3QLS A;  3FRB X;  2ZZA A;  3NZC X;  3KGY A;  4KY4 A;  5JA3 A;  3FQ0 A;  1JOM A;  4XRB A;  1DDS A;  1JOL A;  3DRC A;  1AI9 A;  3F0U X;  1U70 A;  1S3Y A;  3F91 A;  3VCO A;  1PD9 A;  1S3V A;  3QLX A;  4ELE A;  3JSU A;  4NX7 A;  2ITH A;  1DR5 A;  1RG7 A;  3OAF A;  3M08 A;  3HJ3 A;  3M09 A;  1D1G A;  1M78 A;  3K2H A;  1DR2 A;  4QJC A;  1MVT A;  3FQZ A;  2OBC A;  5HI6 A;  1RX5 A;  2GD9 A;  3QYL A;  1IA4 A;  3CLB A;  1RH3 A;  2BLB A;  1J3K A;  4H97 A;  3CL9 A;  1VDR A;  3GHV A;  1RX4 A;  4XT6 A;  2HXV A;  3SH2 A;  3NXX A;  1DHI A;  1OHK A;  3TQB A;  3F8Z A;  1RD7 A;  4OR7 A;  1CD2 A;  3IRO A;  3K45 A;  5HQY A;  1DR6 A;  3N0H A;  3NXT A;  4M6J A;  1QZF A;  2D5N A;  4QI9 A;  4EIZ A;  3D84 X;  3NXY A;  1DR3 A;  4XEC X;  2AZN A;  3F8Y A;  1DYR A;  2HQP A;  3F0Q X;  2ANO A;  5ECX A;  2G6V A;  3SRR X;  3QL0 A;  3SR5 X;  1AOE A;  1TDR A;  4KFJ A;  3TQ8 A;  4FGG A;  5DXV A;  4XT7 A;  4ELF A;  3Q1H A;  2W9T A;  5U27 A;  3K74 A;  3CD2 A;  4FHB A;  5HT4 A;  1RA1 A;  3ROA A;  3QGT A;  1IA1 A;  3DAT A;  2INQ A;  2W3W A;  3DL5 A;  3NZD A;  2BLA A;  4KNE A;  2W3V A;  1RX7 A;  3I8A X;  4PSY A;  3D80 A;  3E0B A;  3NXO A;  1SEJ A;  4RGC A;  4XE6 X;  3R33 A;  1DR7 A;  1U71 A;  2P4G A;  4LAE X;  3FQO A;  4H96 A;  3EX8 A;  1KLK A;  3FRE X;  5HF2 X;  1DIS A;  5HSU A;  3JWM A;  3KJS A;  3FQC A;  4P68 A;  3F0X X;  1RA3 A;  4KM2 A;  3TQA A;  4M6L A;  4KJK A;  3IA4 A;  3NU0 A;  4IXF X;  3KY8 A;  1E26 A;  3S9U A;  1DHJ A;  1YHO A;  4P3Q A;  3IRM A;  4HA7 A;  5EAJ A;  5FDA A;  5CCC A;  4Q0D A;  4KLX A;  4KEB A;  1OHJ A;  1MVS A;  3UM6 A;  2H2Q A;  2D0K A;  2CD2 A;  2ANQ A;  4X5J A;  3SRU X;  3QLR A;  3QYO A;  5JG0 X;  1DLS A;  2C2S A;  4ELH A;  2L28 A;  3GYF A;  1DG5 A;  1ZDR A;  7DFR A;  1DYI A;  5HPB A;  4PSS A;  1RX1 A;  1PD8 A;  4PDJ A;  1AO8 A;  3JW5 A;  3NXV A;  4TU5 X;  4KYA A;  1BZF A;  3JWK A;  3GHC A;  1RX2 A;  3FS6 A;  1DG8 A;  3KFY A;  3RO9 A;  1HFQ A;  1IA3 A;  3INV A;  2OIP A;  1RA9 A;  1DG7 A;  2W3B A;  5ECC A;  3IX9 A;  2LF1 A;  1BOZ A;  4LAH X;  5HT5 A;  6DFR A;  1DIU A;  1S3W A;  4IXG X;  3GI2 A;  4KJJ A;  3DG8 A;  3DL6 A;  3I3R A;  5CC9 A;  4DP3 A;  1U72 A;  1RC4 A;  4QHV A;  3SA2 A;  4ECK A;  3FRA X;  3FL9 A;  1IA2 A;  2FZH A;  3FQF A;  4DPD A;  1DR1 A;  8DFR A;  4PTJ A;  3L3R A;  3HBB A;  4H98 A;  2DRC A;  2HM9 A;  2FZJ A;  4GH8 A;  1RX9 A;  4Q67 A;  2W3A A;  1CZ3 A;  3NZ6 X;  1S3U A;  4HOE A;  3JTW A;  4M6K A;  4ELG A;  4P3R A;  4DFR A;  2BL9 A;  1HFR A;  3QFX A;  1DRA A;  3EEM A;  1RB3 A;  1DF7 A;  3GHW A;  1RA8 A;  3JW3 A;  3SA1 A;  3SRW X;  4M7V A;  1DDR A;  3S3V A;  4XT4 A;  1M79 A;  3NTZ A;  3SRS X;  3EIG A;  2W9G A;  4X5F A;  1RX6 A;  1DHF A;  2W3M A;  1RX3 A;  3DGA A;  3KJR A;  1DLR A;  4G95 A;  3CSE A;  3ZPG A;  1RB2 A;  1LUD A;  4M2X A;  4KY8 A;  2XW7 A;  4I1N A;  4NX6 A;  3FYV X;  3FY8 X;  1JUV A;  4X5I A;  1KMV A;  5U26 A;  2C2T A;  4HOG A;  4Q6A A;  4PST A;  3SGY A;  4XT5 A;  1RF7 A;  4QLF A;  4G8Z X;  1DAJ A;  5HSR A;  5HQZ A;  4M7U A;  4XT8 A;  5HVB A;  1DYJ A;  2O7P A;  1KMS A;  1RE7 A;  4EIG A;  1RA2 A;  1J3J A;  3JWF A;  4KD7 A;  5HVE A;  4DDR A;  4QJZ D; 
#chains in the Genus database with same CATH topology
 4KM0 A;  4QLE A;  1PDB A;  2FZI A;  4OSG A;  3NZ9 X;  1DRB A;  3SRQ X;  4Q0E A;  4X5G A;  4KBN A;  2DHF A;  3F0B X;  3JVX A;  3F0V X;  3IA5 A;  4ELB A;  1HFP A;  4I13 A;  3EEK A;  3RG9 A;  3NZA X;  3UM8 A;  3QLZ A;  3DAU A;  4LEK X;  3FRD X;  2W9H A;  5HUI A;  3TD8 A;  3QLW A;  3TQ9 A;  3LG4 A;  3UM5 A;  3QL3 A;  3FQV A;  4EIL A;  4IXE D;  3JWC A;  3NZB X;  3QLY A;  2KGK A;  3FL8 A;  3K47 A;  3NRR A;  3S7A A;  3DFR A;  2BLC A;  4HOF A;  4HA9 A;  3IRN A;  1DRH A;  2CIG A;  3EEJ A;  2W9S A;  4DPH A;  3QG2 A;  3EEL A;  4KAK A;  3ZPC A;  5HF0 X;  1DYH A;  2JYB A;  4KL9 A;  1LY4 A;  4QLG A;  1M7A A;  1DRE A;  4X5H A;  4KJL A;  3SQY X;  3FRF X;  1DR4 A;  3FY9 X;  4FGH A;  4EJ1 A;  3NXR A;  1VJ3 A;  4G3M A;  2B3Z A;  4PTH A;  1DRF A;  5DFR A;  3SAI A;  3F0S X;  3OCH A;  2QK8 A;  3FYW X;  4LAG X;  4P66 A;  4CD2 A;  5E8Q A;  1LY3 A;  1J3I A;  4H95 A;  1RX8 A;  3QLS A;  3FRB X;  2ZZA A;  3NZC X;  3KGY A;  4KY4 A;  5JA3 A;  3FQ0 A;  1JOM A;  4XRB A;  1DDS A;  1JOL A;  3DRC A;  1AI9 A;  3F0U X;  1U70 A;  1S3Y A;  3F91 A;  3VCO A;  1PD9 A;  1S3V A;  3QLX A;  4ELE A;  3JSU A;  4NX7 A;  2ITH A;  1DR5 A;  1RG7 A;  3OAF A;  3M08 A;  3HJ3 A;  3M09 A;  1D1G A;  1M78 A;  3K2H A;  1DR2 A;  4QJC A;  1MVT A;  3FQZ A;  2OBC A;  5HI6 A;  1RX5 A;  2GD9 A;  3QYL A;  1IA4 A;  3CLB A;  1RH3 A;  2BLB A;  1J3K A;  4H97 A;  3CL9 A;  1VDR A;  3GHV A;  1RX4 A;  4XT6 A;  2HXV A;  3SH2 A;  3NXX A;  1DHI A;  1OHK A;  3TQB A;  3F8Z A;  1RD7 A;  4OR7 A;  1CD2 A;  3IRO A;  3K45 A;  5HQY A;  1DR6 A;  3N0H A;  3NXT A;  4M6J A;  1QZF A;  2D5N A;  4QI9 A;  4EIZ A;  3D84 X;  3NXY A;  1DR3 A;  4XEC X;  2AZN A;  3F8Y A;  1DYR A;  2HQP A;  3F0Q X;  2ANO A;  5ECX A;  2G6V A;  3SRR X;  3QL0 A;  3SR5 X;  1AOE A;  1TDR A;  4KFJ A;  3TQ8 A;  4FGG A;  5DXV A;  4XT7 A;  4ELF A;  3Q1H A;  2W9T A;  5U27 A;  3K74 A;  3CD2 A;  4FHB A;  5HT4 A;  1RA1 A;  3ROA A;  3QGT A;  1IA1 A;  3DAT A;  2INQ A;  2W3W A;  3DL5 A;  3NZD A;  2BLA A;  4KNE A;  2W3V A;  1RX7 A;  3I8A X;  4PSY A;  3D80 A;  3E0B A;  3NXO A;  1SEJ A;  4RGC A;  4XE6 X;  3R33 A;  1DR7 A;  1U71 A;  2P4G A;  4LAE X;  3FQO A;  4H96 A;  3EX8 A;  1KLK A;  3FRE X;  5HF2 X;  1DIS A;  5HSU A;  3JWM A;  3KJS A;  3FQC A;  4P68 A;  3F0X X;  1RA3 A;  4KM2 A;  3TQA A;  4M6L A;  4KJK A;  3IA4 A;  3NU0 A;  4IXF X;  3KY8 A;  1E26 A;  3S9U A;  1DHJ A;  1YHO A;  4P3Q A;  3IRM A;  4HA7 A;  5EAJ A;  5FDA A;  5CCC A;  4Q0D A;  4KLX A;  4KEB A;  1OHJ A;  1MVS A;  3UM6 A;  2H2Q A;  2D0K A;  2CD2 A;  2ANQ A;  4X5J A;  3SRU X;  3QLR A;  3QYO A;  5JG0 X;  1DLS A;  2C2S A;  4ELH A;  2L28 A;  3GYF A;  1DG5 A;  1ZDR A;  7DFR A;  1DYI A;  5HPB A;  4PSS A;  1RX1 A;  1PD8 A;  4PDJ A;  1AO8 A;  3JW5 A;  3NXV A;  4TU5 X;  4KYA A;  1BZF A;  3JWK A;  3GHC A;  1RX2 A;  3FS6 A;  1DG8 A;  3KFY A;  3RO9 A;  1HFQ A;  1IA3 A;  3INV A;  2OIP A;  1RA9 A;  1DG7 A;  2W3B A;  5ECC A;  3IX9 A;  2LF1 A;  1BOZ A;  4LAH X;  5HT5 A;  6DFR A;  1DIU A;  1S3W A;  4IXG X;  3GI2 A;  4KJJ A;  3DG8 A;  3DL6 A;  3I3R A;  5CC9 A;  4DP3 A;  1U72 A;  1RC4 A;  4QHV A;  3SA2 A;  4ECK A;  3FRA X;  3FL9 A;  1IA2 A;  2FZH A;  3FQF A;  4DPD A;  1DR1 A;  8DFR A;  4PTJ A;  3L3R A;  3HBB A;  4H98 A;  2DRC A;  2HM9 A;  2FZJ A;  4GH8 A;  1RX9 A;  4Q67 A;  2W3A A;  1CZ3 A;  3NZ6 X;  1S3U A;  4HOE A;  3JTW A;  4M6K A;  4ELG A;  4P3R A;  4DFR A;  2BL9 A;  1HFR A;  3QFX A;  1DRA A;  3EEM A;  1RB3 A;  1DF7 A;  3GHW A;  1RA8 A;  3JW3 A;  3SA1 A;  3SRW X;  4M7V A;  1DDR A;  3S3V A;  4XT4 A;  1M79 A;  3NTZ A;  3SRS X;  3EIG A;  2W9G A;  4X5F A;  1RX6 A;  1DHF A;  2W3M A;  1RX3 A;  3DGA A;  3KJR A;  1DLR A;  4G95 A;  3CSE A;  3ZPG A;  1RB2 A;  1LUD A;  4M2X A;  4KY8 A;  2XW7 A;  4I1N A;  4NX6 A;  3FYV X;  3FY8 X;  1JUV A;  4X5I A;  1KMV A;  5U26 A;  2C2T A;  4HOG A;  4Q6A A;  4PST A;  3SGY A;  4XT5 A;  1RF7 A;  4QLF A;  4G8Z X;  1DAJ A;  5HSR A;  5HQZ A;  4M7U A;  4XT8 A;  5HVB A;  1DYJ A;  2O7P A;  1KMS A;  1RE7 A;  4EIG A;  1RA2 A;  1J3J A;  3JWF A;  4KD7 A;  5HVE A;  4DDR A;  4QJZ D; 
#chains in the Genus database with same CATH homology
 4KM0 A;  4QLE A;  1PDB A;  2FZI A;  4OSG A;  3NZ9 X;  1DRB A;  3SRQ X;  4Q0E A;  4X5G A;  4KBN A;  2DHF A;  3F0B X;  3JVX A;  3F0V X;  3IA5 A;  4ELB A;  1HFP A;  4I13 A;  3EEK A;  3RG9 A;  3NZA X;  3UM8 A;  3QLZ A;  3DAU A;  4LEK X;  3FRD X;  2W9H A;  5HUI A;  3TD8 A;  3QLW A;  3TQ9 A;  3LG4 A;  3UM5 A;  3QL3 A;  3FQV A;  4EIL A;  4IXE D;  3JWC A;  3NZB X;  3QLY A;  2KGK A;  3FL8 A;  3K47 A;  3NRR A;  3S7A A;  3DFR A;  2BLC A;  4HOF A;  4HA9 A;  3IRN A;  1DRH A;  2CIG A;  3EEJ A;  2W9S A;  4DPH A;  3QG2 A;  3EEL A;  4KAK A;  3ZPC A;  5HF0 X;  1DYH A;  2JYB A;  4KL9 A;  1LY4 A;  4QLG A;  1M7A A;  1DRE A;  4X5H A;  4KJL A;  3SQY X;  3FRF X;  1DR4 A;  3FY9 X;  4FGH A;  4EJ1 A;  3NXR A;  1VJ3 A;  4G3M A;  2B3Z A;  4PTH A;  1DRF A;  5DFR A;  3SAI A;  3F0S X;  3OCH A;  2QK8 A;  3FYW X;  4LAG X;  4P66 A;  4CD2 A;  5E8Q A;  1LY3 A;  1J3I A;  4H95 A;  1RX8 A;  3QLS A;  3FRB X;  2ZZA A;  3NZC X;  3KGY A;  4KY4 A;  5JA3 A;  3FQ0 A;  1JOM A;  4XRB A;  1DDS A;  1JOL A;  3DRC A;  1AI9 A;  3F0U X;  1U70 A;  1S3Y A;  3F91 A;  3VCO A;  1PD9 A;  1S3V A;  3QLX A;  4ELE A;  3JSU A;  4NX7 A;  2ITH A;  1DR5 A;  1RG7 A;  3OAF A;  3M08 A;  3HJ3 A;  3M09 A;  1D1G A;  1M78 A;  3K2H A;  1DR2 A;  4QJC A;  1MVT A;  3FQZ A;  2OBC A;  5HI6 A;  1RX5 A;  2GD9 A;  3QYL A;  1IA4 A;  3CLB A;  1RH3 A;  2BLB A;  1J3K A;  4H97 A;  3CL9 A;  1VDR A;  3GHV A;  1RX4 A;  4XT6 A;  2HXV A;  3SH2 A;  3NXX A;  1DHI A;  1OHK A;  3TQB A;  3F8Z A;  1RD7 A;  4OR7 A;  1CD2 A;  3IRO A;  3K45 A;  5HQY A;  1DR6 A;  3N0H A;  3NXT A;  4M6J A;  1QZF A;  2D5N A;  4QI9 A;  4EIZ A;  3D84 X;  3NXY A;  1DR3 A;  4XEC X;  2AZN A;  3F8Y A;  1DYR A;  2HQP A;  3F0Q X;  2ANO A;  5ECX A;  2G6V A;  3SRR X;  3QL0 A;  3SR5 X;  1AOE A;  1TDR A;  4KFJ A;  3TQ8 A;  4FGG A;  5DXV A;  4XT7 A;  4ELF A;  3Q1H A;  2W9T A;  5U27 A;  3K74 A;  3CD2 A;  4FHB A;  5HT4 A;  1RA1 A;  3ROA A;  3QGT A;  1IA1 A;  3DAT A;  2INQ A;  2W3W A;  3DL5 A;  3NZD A;  2BLA A;  4KNE A;  2W3V A;  1RX7 A;  3I8A X;  4PSY A;  3D80 A;  3E0B A;  3NXO A;  1SEJ A;  4RGC A;  4XE6 X;  3R33 A;  1DR7 A;  1U71 A;  2P4G A;  4LAE X;  3FQO A;  4H96 A;  3EX8 A;  1KLK A;  3FRE X;  5HF2 X;  1DIS A;  5HSU A;  3JWM A;  3KJS A;  3FQC A;  4P68 A;  3F0X X;  1RA3 A;  4KM2 A;  3TQA A;  4M6L A;  4KJK A;  3IA4 A;  3NU0 A;  4IXF X;  3KY8 A;  1E26 A;  3S9U A;  1DHJ A;  1YHO A;  4P3Q A;  3IRM A;  4HA7 A;  5EAJ A;  5FDA A;  5CCC A;  4Q0D A;  4KLX A;  4KEB A;  1OHJ A;  1MVS A;  3UM6 A;  2H2Q A;  2D0K A;  2CD2 A;  2ANQ A;  4X5J A;  3SRU X;  3QLR A;  3QYO A;  5JG0 X;  1DLS A;  2C2S A;  4ELH A;  2L28 A;  3GYF A;  1DG5 A;  1ZDR A;  7DFR A;  1DYI A;  5HPB A;  4PSS A;  1RX1 A;  1PD8 A;  4PDJ A;  1AO8 A;  3JW5 A;  3NXV A;  4TU5 X;  4KYA A;  1BZF A;  3JWK A;  3GHC A;  1RX2 A;  3FS6 A;  1DG8 A;  3KFY A;  3RO9 A;  1HFQ A;  1IA3 A;  3INV A;  2OIP A;  1RA9 A;  1DG7 A;  2W3B A;  5ECC A;  3IX9 A;  2LF1 A;  1BOZ A;  4LAH X;  5HT5 A;  6DFR A;  1DIU A;  1S3W A;  4IXG X;  3GI2 A;  4KJJ A;  3DG8 A;  3DL6 A;  3I3R A;  5CC9 A;  4DP3 A;  1U72 A;  1RC4 A;  4QHV A;  3SA2 A;  4ECK A;  3FRA X;  3FL9 A;  1IA2 A;  2FZH A;  3FQF A;  4DPD A;  1DR1 A;  8DFR A;  4PTJ A;  3L3R A;  3HBB A;  4H98 A;  2DRC A;  2HM9 A;  2FZJ A;  4GH8 A;  1RX9 A;  4Q67 A;  2W3A A;  1CZ3 A;  3NZ6 X;  1S3U A;  4HOE A;  3JTW A;  4M6K A;  4ELG A;  4P3R A;  4DFR A;  2BL9 A;  1HFR A;  3QFX A;  1DRA A;  3EEM A;  1RB3 A;  1DF7 A;  3GHW A;  1RA8 A;  3JW3 A;  3SA1 A;  3SRW X;  4M7V A;  1DDR A;  3S3V A;  4XT4 A;  1M79 A;  3NTZ A;  3SRS X;  3EIG A;  2W9G A;  4X5F A;  1RX6 A;  1DHF A;  2W3M A;  1RX3 A;  3DGA A;  3KJR A;  1DLR A;  4G95 A;  3CSE A;  3ZPG A;  1RB2 A;  1LUD A;  4M2X A;  4KY8 A;  2XW7 A;  4I1N A;  4NX6 A;  3FYV X;  3FY8 X;  1JUV A;  4X5I A;  1KMV A;  5U26 A;  2C2T A;  4HOG A;  4Q6A A;  4PST A;  3SGY A;  4XT5 A;  1RF7 A;  4QLF A;  4G8Z X;  1DAJ A;  5HSR A;  5HQZ A;  4M7U A;  4XT8 A;  5HVB A;  1DYJ A;  2O7P A;  1KMS A;  1RE7 A;  4EIG A;  1RA2 A;  1J3J A;  3JWF A;  4KD7 A;  5HVE A;  4DDR A;  4QJZ D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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