4P3QA

Room-temperature wt dhfr, time-averaged ensemble
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Dihydrofolate reductase
total genus 38
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-03-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4p3qA00
3S7AA 3NXRA 1IA2A 1KMVA 4EILA 3GI2A 3K74A 4M7UA 3FRFX 3SA2A 1IA1A 3IRNA 3IA4A 1E26A 4NX7A 1DISA 1RF7A 3QLSA 3ROAA 3JW5A 3IX9A 4ELEA 1DR4A 1DR2A 4OSGA 3SGYA 5DXVA 3KJSA 3RG9A 3NRRA 3FQZA 1DLRA 3CD2A 4XT5A 5JA3A 4P66A 1U72A 4GH8A 1LY3A 2GD9A 4EJ1A 3QLRA 1CZ3A 1DIUA 1YHOA 2CIGA 2C2SA 4DDRA 3SRSX 5HT4A 3JW3A 4PSYA 4EIZA 4X5FA 1DR5A 2DRCA 4PSSA 4QLFA 3FYVX 3F8ZA 3NZDA 3INVA 1S3VA 4IXFX 4KLXA 3OAFA 3FL8A 1DHIA 1CD2A 4DPHA 3FQFA 1DYRA 3Q1HA 1HFPA 2HQPA 1DDRA 3F0QX 5ECCA 3CLBA 3I3RA 5HF0X 4HOEA 2BL9A 4M6JA 4M6KA 1S3YA 4KL9A 3FREX 4KY4A 1DRHA 2W3VA 3FYWX 5DFRA 3EEJA 4OR7A 3NTZA 4I1NA 1DR3A 1RX3A 5HVBA 3FQ0A 7DFRA 4KJJA 3TQBA 1LUDA 3RO9A 3GHWA 3VCOA 4PTJA 2HM9A 4X5GA 4LAGX 3JSUA 2FZIA 2HXVA 1OHJA 4DPDA 3NXOA 3F0BX 4P3QA 3GHCA 4IXED 4PTHA 3TQAA 1RB2A 1JOMA 4Q0EA 5HSRA 4FGHA 1KLKA 3DG8A 4XT7A 3JTWA 3NZ6X 1ZDRA 1S3WA 5HF2X 2W3WA 4KD7A 3FQVA 4KEBA 5HPBA 3JWKA 4XE6X 3EEKA 1RA3A 4M2XA 4HA9A 3M08A 4X5IA 4I13A 2INQA 1VDRA 1JUVA 3DGAA 1AI9A 1RA2A 2OBCA 3UM6A 4IXGX 3QL0A 1RA1A 4ELBA 1RA9A 4M6LA 3NXTA 4QI9A 2W3BA 1RD7A 3FS6A 1IA3A 4Q6AA 1QZFA 4Q0DA 5E8QA 3DL5A 3K45A 1BZFA 3L3RA 4Q67A 2H2QA 3SRRX 1S3UA 3JWCA 5CC9A 2QK8A 1RE7A 4EIGA 3F0XX 4DP3A 1RX7A 1MVTA 4KAKA 5HI6A 1SEJA 5HVEA 3UM5A 1RX8A 3QYOA 4ECKA 5HQZA 4X5JA 3SH2A 5CCCA 4H95A 1RX4A 2ANQA 3IROA 4HA7A 3SRQX 2L28A 4G3MA 5HT5A 4XT8A 3NXXA 3OCHA 3IA5A 1DREA 3DATA 3I8AX 4G95A 4KBNA 3HBBA 2W9GA 4XECX 4P68A 4XT4A 1DF7A 3QLWA 2OIPA 3FRBX 3JVXA 4CD2A 1U70A 3NXVA 2AZNA 2XW7A 1DHJA 1IA4A 4XRBA 1AOEA 3SA1A 5EAJA 1HFRA 1VJ3A 2ITHA 2W9TA 3M09A 2CD2A 2O7PA 1PDBA 5ECXA 4QLEA 4HOGA 1M79A 3CSEA 1RX1A 3FY8X 4KJLA 5HUIA 5HSUA 4KYAA 3QLYA 3F0VX 1TDRA 1DDSA 1BOZA 1DG5A 4TU5X 2B3ZA 3D84X 4KY8A 3NZCX 4KJKA 3FRAX 3DAUA 3EIGA 2FZHA 3FQOA 3S9UA 3SQYX 3F0SX 3DFRA 1DR7A 3QLXA 3SAIA 3QG2A 2DHFA 3LG4A 4FHBA 4QHVA 1PD9A 3F91A 3NZ9X 1M7AA 4NX6A 4LAEX 1M78A 3D80A 3QGTA 3DRCA 4X5HA 5JG0X 2P4GA 3KJRA 1DYJA 4LEKX 1DYHA 2W9SA 2ZZAA 4KFJA 2KGKA 2W3MA 3EX8A 1KMSA 4QLGA 1RX6A 3ZPGA 1J3JA 1RC4A 1DG8A 1MVSA 1JOLA 3FL9A 3UM8A 3QFXA 3TQ8A 3IRMA 3CL9A 3QLZA 3EELA 1AO8A 2LF1A 3N0HA 3K47A 4M7VA 2G6VA 4KM0A 3NU0A 3NZBX 4ELFA 1DRFA 3HJ3A 3F8YA 1RB3A 3FY9X 5U26A 1DR1A 4FGGA 1HFQA 2D0KA 4H97A 3FQCA 3DL6A 3KGYA 1U71A 2BLBA 4RGCA 1RX9A 2BLCA 1DG7A 3SR5X 8DFRA 2FZJA 1DRBA 1RG7A 4H96A 2D5NA 3QL3A 3S3VA 3TQ9A 1PD8A 3SRWX 1LY4A 2ANOA 2W3AA 1RH3A 4PDJA 1RX2A 3KY8A 3FRDX 4P3RA 5U27A 4XT6A 4ELHA 5FDAA 1DAJA 2JYBA 1D1GA 4QJCA 4KNEA 3NXYA 4KM2A 3NZAX 1DHFA 3QYLA 4H98A 4DFRA 6DFRA 1J3KA 2C2TA 3GHVA 3JWMA 1DLSA 3TD8A 1DR6A 1OHKA 3R33A 3EEMA 4HOFA 2W9HA 5HQYA 3GYFA 1RX5A 4QJZD 4ELGA 1J3IA 2BLAA 1RA8A 1DYIA 3KFYA 4LAHX 1DRAA 3SRUX 3K2HA 3F0UX 4PSTA 4G8ZX 3E0BA 3ZPCA 3JWFA
chains in the Genus database with same CATH superfamily
3S7AA 3NXRA 1IA2A 1KMVA 4EILA 3GI2A 3K74A 4M7UA 3FRFX 3SA2A 1IA1A 3IRNA 3IA4A 1E26A 4NX7A 1DISA 1RF7A 3QLSA 3ROAA 3JW5A 3IX9A 4ELEA 1DR4A 1DR2A 4OSGA 3SGYA 5DXVA 3KJSA 3RG9A 3NRRA 3FQZA 1DLRA 3CD2A 4XT5A 5JA3A 4P66A 1U72A 4GH8A 1LY3A 2GD9A 4EJ1A 3QLRA 1CZ3A 1DIUA 1YHOA 2CIGA 2C2SA 4DDRA 3SRSX 5HT4A 3JW3A 4PSYA 4EIZA 4X5FA 1DR5A 2DRCA 4PSSA 4QLFA 3FYVX 3F8ZA 3NZDA 3INVA 1S3VA 4IXFX 4KLXA 3OAFA 3FL8A 1DHIA 1CD2A 4DPHA 3FQFA 1DYRA 3Q1HA 1HFPA 2HQPA 1DDRA 3F0QX 5ECCA 3CLBA 3I3RA 5HF0X 4HOEA 2BL9A 4M6JA 4M6KA 1S3YA 4KL9A 3FREX 4KY4A 1DRHA 2W3VA 3FYWX 5DFRA 3EEJA 4OR7A 3NTZA 4I1NA 1DR3A 1RX3A 5HVBA 3FQ0A 7DFRA 4KJJA 3TQBA 1LUDA 3RO9A 3GHWA 3VCOA 4PTJA 2HM9A 4X5GA 4LAGX 3JSUA 2FZIA 2HXVA 1OHJA 4DPDA 3NXOA 3F0BX 4P3QA 3GHCA 4IXED 4PTHA 3TQAA 1RB2A 1JOMA 4Q0EA 5HSRA 4FGHA 1KLKA 3DG8A 4XT7A 3JTWA 3NZ6X 1ZDRA 1S3WA 5HF2X 2W3WA 4KD7A 3FQVA 4KEBA 5HPBA 3JWKA 4XE6X 3EEKA 1RA3A 4M2XA 4HA9A 3M08A 4X5IA 4I13A 2INQA 1VDRA 1JUVA 3DGAA 1AI9A 1RA2A 2OBCA 3UM6A 4IXGX 3QL0A 1RA1A 4ELBA 1RA9A 4M6LA 3NXTA 4QI9A 2W3BA 1RD7A 3FS6A 1IA3A 4Q6AA 1QZFA 4Q0DA 5E8QA 3DL5A 3K45A 1BZFA 3L3RA 4Q67A 2H2QA 3SRRX 1S3UA 3JWCA 5CC9A 2QK8A 1RE7A 4EIGA 3F0XX 4DP3A 1RX7A 1MVTA 4KAKA 5HI6A 1SEJA 5HVEA 3UM5A 1RX8A 3QYOA 4ECKA 5HQZA 4X5JA 3SH2A 5CCCA 4H95A 1RX4A 2ANQA 3IROA 4HA7A 3SRQX 2L28A 4G3MA 5HT5A 4XT8A 3NXXA 3OCHA 3IA5A 1DREA 3DATA 3I8AX 4G95A 4KBNA 3HBBA 2W9GA 4XECX 4P68A 4XT4A 1DF7A 3QLWA 2OIPA 3FRBX 3JVXA 4CD2A 1U70A 3NXVA 2AZNA 2XW7A 1DHJA 1IA4A 4XRBA 1AOEA 3SA1A 5EAJA 1HFRA 1VJ3A 2ITHA 2W9TA 3M09A 2CD2A 2O7PA 1PDBA 5ECXA 4QLEA 4HOGA 1M79A 3CSEA 1RX1A 3FY8X 4KJLA 5HUIA 5HSUA 4KYAA 3QLYA 3F0VX 1TDRA 1DDSA 1BOZA 1DG5A 4TU5X 2B3ZA 3D84X 4KY8A 3NZCX 4KJKA 3FRAX 3DAUA 3EIGA 2FZHA 3FQOA 3S9UA 3SQYX 3F0SX 3DFRA 1DR7A 3QLXA 3SAIA 3QG2A 2DHFA 3LG4A 4FHBA 4QHVA 1PD9A 3F91A 3NZ9X 1M7AA 4NX6A 4LAEX 1M78A 3D80A 3QGTA 3DRCA 4X5HA 5JG0X 2P4GA 3KJRA 1DYJA 4LEKX 1DYHA 2W9SA 2ZZAA 4KFJA 2KGKA 2W3MA 3EX8A 1KMSA 4QLGA 1RX6A 3ZPGA 1J3JA 1RC4A 1DG8A 1MVSA 1JOLA 3FL9A 3UM8A 3QFXA 3TQ8A 3IRMA 3CL9A 3QLZA 3EELA 1AO8A 2LF1A 3N0HA 3K47A 4M7VA 2G6VA 4KM0A 3NU0A 3NZBX 4ELFA 1DRFA 3HJ3A 3F8YA 1RB3A 3FY9X 5U26A 1DR1A 4FGGA 1HFQA 2D0KA 4H97A 3FQCA 3DL6A 3KGYA 1U71A 2BLBA 4RGCA 1RX9A 2BLCA 1DG7A 3SR5X 8DFRA 2FZJA 1DRBA 1RG7A 4H96A 2D5NA 3QL3A 3S3VA 3TQ9A 1PD8A 3SRWX 1LY4A 2ANOA 2W3AA 1RH3A 4PDJA 1RX2A 3KY8A 3FRDX 4P3RA 5U27A 4XT6A 4ELHA 5FDAA 1DAJA 2JYBA 1D1GA 4QJCA 4KNEA 3NXYA 4KM2A 3NZAX 1DHFA 3QYLA 4H98A 4DFRA 6DFRA 1J3KA 2C2TA 3GHVA 3JWMA 1DLSA 3TD8A 1DR6A 1OHKA 3R33A 3EEMA 4HOFA 2W9HA 5HQYA 3GYFA 1RX5A 4QJZD 4ELGA 1J3IA 2BLAA 1RA8A 1DYIA 3KFYA 4LAHX 1DRAA 3SRUX 3K2HA 3F0UX 4PSTA 4G8ZX 3E0BA 3ZPCA 3JWFA
chains in the Genus database with same CATH topology
3S7AA 3NXRA 1IA2A 1KMVA 4EILA 3GI2A 3K74A 4M7UA 3FRFX 3SA2A 1IA1A 3IRNA 3IA4A 1E26A 4NX7A 1DISA 1RF7A 3QLSA 3ROAA 3JW5A 3IX9A 4ELEA 1DR4A 1DR2A 4OSGA 3SGYA 5DXVA 3KJSA 3RG9A 3NRRA 3FQZA 1DLRA 3CD2A 4XT5A 5JA3A 4P66A 1U72A 4GH8A 1LY3A 2GD9A 4EJ1A 3QLRA 1CZ3A 1DIUA 1YHOA 2CIGA 2C2SA 4DDRA 3SRSX 5HT4A 3JW3A 4PSYA 4EIZA 4X5FA 1DR5A 2DRCA 4PSSA 4QLFA 3FYVX 3F8ZA 3NZDA 3INVA 1S3VA 4IXFX 4KLXA 3OAFA 3FL8A 1DHIA 1CD2A 4DPHA 3FQFA 1DYRA 3Q1HA 1HFPA 2HQPA 1DDRA 3F0QX 5ECCA 3CLBA 3I3RA 5HF0X 4HOEA 2BL9A 4M6JA 4M6KA 1S3YA 4KL9A 3FREX 4KY4A 1DRHA 2W3VA 3FYWX 5DFRA 3EEJA 4OR7A 3NTZA 4I1NA 1DR3A 1RX3A 5HVBA 3FQ0A 7DFRA 4KJJA 3TQBA 1LUDA 3RO9A 3GHWA 3VCOA 4PTJA 2HM9A 4X5GA 4LAGX 3JSUA 2FZIA 2HXVA 1OHJA 4DPDA 3NXOA 3F0BX 4P3QA 3GHCA 4IXED 4PTHA 3TQAA 1RB2A 1JOMA 4Q0EA 5HSRA 4FGHA 1KLKA 3DG8A 4XT7A 3JTWA 3NZ6X 1ZDRA 1S3WA 5HF2X 2W3WA 4KD7A 3FQVA 4KEBA 5HPBA 3JWKA 4XE6X 3EEKA 1RA3A 4M2XA 4HA9A 3M08A 4X5IA 4I13A 2INQA 1VDRA 1JUVA 3DGAA 1AI9A 1RA2A 2OBCA 3UM6A 4IXGX 3QL0A 1RA1A 4ELBA 1RA9A 4M6LA 3NXTA 4QI9A 2W3BA 1RD7A 3FS6A 1IA3A 4Q6AA 1QZFA 4Q0DA 5E8QA 3DL5A 3K45A 1BZFA 3L3RA 4Q67A 2H2QA 3SRRX 1S3UA 3JWCA 5CC9A 2QK8A 1RE7A 4EIGA 3F0XX 4DP3A 1RX7A 1MVTA 4KAKA 5HI6A 1SEJA 5HVEA 3UM5A 1RX8A 3QYOA 4ECKA 5HQZA 4X5JA 3SH2A 5CCCA 4H95A 1RX4A 2ANQA 3IROA 4HA7A 3SRQX 2L28A 4G3MA 5HT5A 4XT8A 3NXXA 3OCHA 3IA5A 1DREA 3DATA 3I8AX 4G95A 4KBNA 3HBBA 2W9GA 4XECX 4P68A 4XT4A 1DF7A 3QLWA 2OIPA 3FRBX 3JVXA 4CD2A 1U70A 3NXVA 2AZNA 2XW7A 1DHJA 1IA4A 4XRBA 1AOEA 3SA1A 5EAJA 1HFRA 1VJ3A 2ITHA 2W9TA 3M09A 2CD2A 2O7PA 1PDBA 5ECXA 4QLEA 4HOGA 1M79A 3CSEA 1RX1A 3FY8X 4KJLA 5HUIA 5HSUA 4KYAA 3QLYA 3F0VX 1TDRA 1DDSA 1BOZA 1DG5A 4TU5X 2B3ZA 3D84X 4KY8A 3NZCX 4KJKA 3FRAX 3DAUA 3EIGA 2FZHA 3FQOA 3S9UA 3SQYX 3F0SX 3DFRA 1DR7A 3QLXA 3SAIA 3QG2A 2DHFA 3LG4A 4FHBA 4QHVA 1PD9A 3F91A 3NZ9X 1M7AA 4NX6A 4LAEX 1M78A 3D80A 3QGTA 3DRCA 4X5HA 5JG0X 2P4GA 3KJRA 1DYJA 4LEKX 1DYHA 2W9SA 2ZZAA 4KFJA 2KGKA 2W3MA 3EX8A 1KMSA 4QLGA 1RX6A 3ZPGA 1J3JA 1RC4A 1DG8A 1MVSA 1JOLA 3FL9A 3UM8A 3QFXA 3TQ8A 3IRMA 3CL9A 3QLZA 3EELA 1AO8A 2LF1A 3N0HA 3K47A 4M7VA 2G6VA 4KM0A 3NU0A 3NZBX 4ELFA 1DRFA 3HJ3A 3F8YA 1RB3A 3FY9X 5U26A 1DR1A 4FGGA 1HFQA 2D0KA 4H97A 3FQCA 3DL6A 3KGYA 1U71A 2BLBA 4RGCA 1RX9A 2BLCA 1DG7A 3SR5X 8DFRA 2FZJA 1DRBA 1RG7A 4H96A 2D5NA 3QL3A 3S3VA 3TQ9A 1PD8A 3SRWX 1LY4A 2ANOA 2W3AA 1RH3A 4PDJA 1RX2A 3KY8A 3FRDX 4P3RA 5U27A 4XT6A 4ELHA 5FDAA 1DAJA 2JYBA 1D1GA 4QJCA 4KNEA 3NXYA 4KM2A 3NZAX 1DHFA 3QYLA 4H98A 4DFRA 6DFRA 1J3KA 2C2TA 3GHVA 3JWMA 1DLSA 3TD8A 1DR6A 1OHKA 3R33A 3EEMA 4HOFA 2W9HA 5HQYA 3GYFA 1RX5A 4QJZD 4ELGA 1J3IA 2BLAA 1RA8A 1DYIA 3KFYA 4LAHX 1DRAA 3SRUX 3K2HA 3F0UX 4PSTA 4G8ZX 3E0BA 3ZPCA 3JWFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S7A A;  3NXR A;  1IA2 A;  1KMV A;  4EIL A;  3GI2 A;  3K74 A;  4M7U A;  3FRF X;  3SA2 A;  1IA1 A;  3IRN A;  3IA4 A;  1E26 A;  4NX7 A;  1DIS A;  1RF7 A;  3QLS A;  3ROA A;  3JW5 A;  3IX9 A;  4ELE A;  1DR4 A;  1DR2 A;  4OSG A;  3SGY A;  5DXV A;  3KJS A;  3RG9 A;  3NRR A;  3FQZ A;  1DLR A;  3CD2 A;  4XT5 A;  5JA3 A;  4P66 A;  1U72 A;  4GH8 A;  1LY3 A;  2GD9 A;  4EJ1 A;  3QLR A;  1CZ3 A;  1DIU A;  1YHO A;  2CIG A;  2C2S A;  4DDR A;  3SRS X;  5HT4 A;  3JW3 A;  4PSY A;  4EIZ A;  4X5F A;  1DR5 A;  2DRC A;  4PSS A;  4QLF A;  3FYV X;  3F8Z A;  3NZD A;  3INV A;  1S3V A;  4IXF X;  4KLX A;  3OAF A;  3FL8 A;  1DHI A;  1CD2 A;  4DPH A;  3FQF A;  1DYR A;  3Q1H A;  1HFP A;  2HQP A;  1DDR A;  3F0Q X;  5ECC A;  3CLB A;  3I3R A;  5HF0 X;  4HOE A;  2BL9 A;  4M6J A;  4M6K A;  1S3Y A;  4KL9 A;  3FRE X;  4KY4 A;  1DRH A;  2W3V A;  3FYW X;  5DFR A;  3EEJ A;  4OR7 A;  3NTZ A;  4I1N A;  1DR3 A;  1RX3 A;  5HVB A;  3FQ0 A;  7DFR A;  4KJJ A;  3TQB A;  1LUD A;  3RO9 A;  3GHW A;  3VCO A;  4PTJ A;  2HM9 A;  4X5G A;  4LAG X;  3JSU A;  2FZI A;  2HXV A;  1OHJ A;  4DPD A;  3NXO A;  3F0B X;  4P3Q A;  3GHC A;  4IXE D;  4PTH A;  3TQA A;  1RB2 A;  1JOM A;  4Q0E A;  5HSR A;  4FGH A;  1KLK A;  3DG8 A;  4XT7 A;  3JTW A;  3NZ6 X;  1ZDR A;  1S3W A;  5HF2 X;  2W3W A;  4KD7 A;  3FQV A;  4KEB A;  5HPB A;  3JWK A;  4XE6 X;  3EEK A;  1RA3 A;  4M2X A;  4HA9 A;  3M08 A;  4X5I A;  4I13 A;  2INQ A;  1VDR A;  1JUV A;  3DGA A;  1AI9 A;  1RA2 A;  2OBC A;  3UM6 A;  4IXG X;  3QL0 A;  1RA1 A;  4ELB A;  1RA9 A;  4M6L A;  3NXT A;  4QI9 A;  2W3B A;  1RD7 A;  3FS6 A;  1IA3 A;  4Q6A A;  1QZF A;  4Q0D A;  5E8Q A;  3DL5 A;  3K45 A;  1BZF A;  3L3R A;  4Q67 A;  2H2Q A;  3SRR X;  1S3U A;  3JWC A;  5CC9 A;  2QK8 A;  1RE7 A;  4EIG A;  3F0X X;  4DP3 A;  1RX7 A;  1MVT A;  4KAK A;  5HI6 A;  1SEJ A;  5HVE A;  3UM5 A;  1RX8 A;  3QYO A;  4ECK A;  5HQZ A;  4X5J A;  3SH2 A;  5CCC A;  4H95 A;  1RX4 A;  2ANQ A;  3IRO A;  4HA7 A;  3SRQ X;  2L28 A;  4G3M A;  5HT5 A;  4XT8 A;  3NXX A;  3OCH A;  3IA5 A;  1DRE A;  3DAT A;  3I8A X;  4G95 A;  4KBN A;  3HBB A;  2W9G A;  4XEC X;  4P68 A;  4XT4 A;  1DF7 A;  3QLW A;  2OIP A;  3FRB X;  3JVX A;  4CD2 A;  1U70 A;  3NXV A;  2AZN A;  2XW7 A;  1DHJ A;  1IA4 A;  4XRB A;  1AOE A;  3SA1 A;  5EAJ A;  1HFR A;  1VJ3 A;  2ITH A;  2W9T A;  3M09 A;  2CD2 A;  2O7P A;  1PDB A;  5ECX A;  4QLE A;  4HOG A;  1M79 A;  3CSE A;  1RX1 A;  3FY8 X;  4KJL A;  5HUI A;  5HSU A;  4KYA A;  3QLY A;  3F0V X;  1TDR A;  1DDS A;  1BOZ A;  1DG5 A;  4TU5 X;  2B3Z A;  3D84 X;  4KY8 A;  3NZC X;  4KJK A;  3FRA X;  3DAU A;  3EIG A;  2FZH A;  3FQO A;  3S9U A;  3SQY X;  3F0S X;  3DFR A;  1DR7 A;  3QLX A;  3SAI A;  3QG2 A;  2DHF A;  3LG4 A;  4FHB A;  4QHV A;  1PD9 A;  3F91 A;  3NZ9 X;  1M7A A;  4NX6 A;  4LAE X;  1M78 A;  3D80 A;  3QGT A;  3DRC A;  4X5H A;  5JG0 X;  2P4G A;  3KJR A;  1DYJ A;  4LEK X;  1DYH A;  2W9S A;  2ZZA A;  4KFJ A;  2KGK A;  2W3M A;  3EX8 A;  1KMS A;  4QLG A;  1RX6 A;  3ZPG A;  1J3J A;  1RC4 A;  1DG8 A;  1MVS A;  1JOL A;  3FL9 A;  3UM8 A;  3QFX A;  3TQ8 A;  3IRM A;  3CL9 A;  3QLZ A;  3EEL A;  1AO8 A;  2LF1 A;  3N0H A;  3K47 A;  4M7V A;  2G6V A;  4KM0 A;  3NU0 A;  3NZB X;  4ELF A;  1DRF A;  3HJ3 A;  3F8Y A;  1RB3 A;  3FY9 X;  5U26 A;  1DR1 A;  4FGG A;  1HFQ A;  2D0K A;  4H97 A;  3FQC A;  3DL6 A;  3KGY A;  1U71 A;  2BLB A;  4RGC A;  1RX9 A;  2BLC A;  1DG7 A;  3SR5 X;  8DFR A;  2FZJ A;  1DRB A;  1RG7 A;  4H96 A;  2D5N A;  3QL3 A;  3S3V A;  3TQ9 A;  1PD8 A;  3SRW X;  1LY4 A;  2ANO A;  2W3A A;  1RH3 A;  4PDJ A;  1RX2 A;  3KY8 A;  3FRD X;  4P3R A;  5U27 A;  4XT6 A;  4ELH A;  5FDA A;  1DAJ A;  2JYB A;  1D1G A;  4QJC A;  4KNE A;  3NXY A;  4KM2 A;  3NZA X;  1DHF A;  3QYL A;  4H98 A;  4DFR A;  6DFR A;  1J3K A;  2C2T A;  3GHV A;  3JWM A;  1DLS A;  3TD8 A;  1DR6 A;  1OHK A;  3R33 A;  3EEM A;  4HOF A;  2W9H A;  5HQY A;  3GYF A;  1RX5 A;  4QJZ D;  4ELG A;  1J3I A;  2BLA A;  1RA8 A;  1DYI A;  3KFY A;  4LAH X;  1DRA A;  3SRU X;  3K2H A;  3F0U X;  4PST A;  4G8Z X;  3E0B A;  3ZPC A;  3JWF A; 
#chains in the Genus database with same CATH topology
 3S7A A;  3NXR A;  1IA2 A;  1KMV A;  4EIL A;  3GI2 A;  3K74 A;  4M7U A;  3FRF X;  3SA2 A;  1IA1 A;  3IRN A;  3IA4 A;  1E26 A;  4NX7 A;  1DIS A;  1RF7 A;  3QLS A;  3ROA A;  3JW5 A;  3IX9 A;  4ELE A;  1DR4 A;  1DR2 A;  4OSG A;  3SGY A;  5DXV A;  3KJS A;  3RG9 A;  3NRR A;  3FQZ A;  1DLR A;  3CD2 A;  4XT5 A;  5JA3 A;  4P66 A;  1U72 A;  4GH8 A;  1LY3 A;  2GD9 A;  4EJ1 A;  3QLR A;  1CZ3 A;  1DIU A;  1YHO A;  2CIG A;  2C2S A;  4DDR A;  3SRS X;  5HT4 A;  3JW3 A;  4PSY A;  4EIZ A;  4X5F A;  1DR5 A;  2DRC A;  4PSS A;  4QLF A;  3FYV X;  3F8Z A;  3NZD A;  3INV A;  1S3V A;  4IXF X;  4KLX A;  3OAF A;  3FL8 A;  1DHI A;  1CD2 A;  4DPH A;  3FQF A;  1DYR A;  3Q1H A;  1HFP A;  2HQP A;  1DDR A;  3F0Q X;  5ECC A;  3CLB A;  3I3R A;  5HF0 X;  4HOE A;  2BL9 A;  4M6J A;  4M6K A;  1S3Y A;  4KL9 A;  3FRE X;  4KY4 A;  1DRH A;  2W3V A;  3FYW X;  5DFR A;  3EEJ A;  4OR7 A;  3NTZ A;  4I1N A;  1DR3 A;  1RX3 A;  5HVB A;  3FQ0 A;  7DFR A;  4KJJ A;  3TQB A;  1LUD A;  3RO9 A;  3GHW A;  3VCO A;  4PTJ A;  2HM9 A;  4X5G A;  4LAG X;  3JSU A;  2FZI A;  2HXV A;  1OHJ A;  4DPD A;  3NXO A;  3F0B X;  4P3Q A;  3GHC A;  4IXE D;  4PTH A;  3TQA A;  1RB2 A;  1JOM A;  4Q0E A;  5HSR A;  4FGH A;  1KLK A;  3DG8 A;  4XT7 A;  3JTW A;  3NZ6 X;  1ZDR A;  1S3W A;  5HF2 X;  2W3W A;  4KD7 A;  3FQV A;  4KEB A;  5HPB A;  3JWK A;  4XE6 X;  3EEK A;  1RA3 A;  4M2X A;  4HA9 A;  3M08 A;  4X5I A;  4I13 A;  2INQ A;  1VDR A;  1JUV A;  3DGA A;  1AI9 A;  1RA2 A;  2OBC A;  3UM6 A;  4IXG X;  3QL0 A;  1RA1 A;  4ELB A;  1RA9 A;  4M6L A;  3NXT A;  4QI9 A;  2W3B A;  1RD7 A;  3FS6 A;  1IA3 A;  4Q6A A;  1QZF A;  4Q0D A;  5E8Q A;  3DL5 A;  3K45 A;  1BZF A;  3L3R A;  4Q67 A;  2H2Q A;  3SRR X;  1S3U A;  3JWC A;  5CC9 A;  2QK8 A;  1RE7 A;  4EIG A;  3F0X X;  4DP3 A;  1RX7 A;  1MVT A;  4KAK A;  5HI6 A;  1SEJ A;  5HVE A;  3UM5 A;  1RX8 A;  3QYO A;  4ECK A;  5HQZ A;  4X5J A;  3SH2 A;  5CCC A;  4H95 A;  1RX4 A;  2ANQ A;  3IRO A;  4HA7 A;  3SRQ X;  2L28 A;  4G3M A;  5HT5 A;  4XT8 A;  3NXX A;  3OCH A;  3IA5 A;  1DRE A;  3DAT A;  3I8A X;  4G95 A;  4KBN A;  3HBB A;  2W9G A;  4XEC X;  4P68 A;  4XT4 A;  1DF7 A;  3QLW A;  2OIP A;  3FRB X;  3JVX A;  4CD2 A;  1U70 A;  3NXV A;  2AZN A;  2XW7 A;  1DHJ A;  1IA4 A;  4XRB A;  1AOE A;  3SA1 A;  5EAJ A;  1HFR A;  1VJ3 A;  2ITH A;  2W9T A;  3M09 A;  2CD2 A;  2O7P A;  1PDB A;  5ECX A;  4QLE A;  4HOG A;  1M79 A;  3CSE A;  1RX1 A;  3FY8 X;  4KJL A;  5HUI A;  5HSU A;  4KYA A;  3QLY A;  3F0V X;  1TDR A;  1DDS A;  1BOZ A;  1DG5 A;  4TU5 X;  2B3Z A;  3D84 X;  4KY8 A;  3NZC X;  4KJK A;  3FRA X;  3DAU A;  3EIG A;  2FZH A;  3FQO A;  3S9U A;  3SQY X;  3F0S X;  3DFR A;  1DR7 A;  3QLX A;  3SAI A;  3QG2 A;  2DHF A;  3LG4 A;  4FHB A;  4QHV A;  1PD9 A;  3F91 A;  3NZ9 X;  1M7A A;  4NX6 A;  4LAE X;  1M78 A;  3D80 A;  3QGT A;  3DRC A;  4X5H A;  5JG0 X;  2P4G A;  3KJR A;  1DYJ A;  4LEK X;  1DYH A;  2W9S A;  2ZZA A;  4KFJ A;  2KGK A;  2W3M A;  3EX8 A;  1KMS A;  4QLG A;  1RX6 A;  3ZPG A;  1J3J A;  1RC4 A;  1DG8 A;  1MVS A;  1JOL A;  3FL9 A;  3UM8 A;  3QFX A;  3TQ8 A;  3IRM A;  3CL9 A;  3QLZ A;  3EEL A;  1AO8 A;  2LF1 A;  3N0H A;  3K47 A;  4M7V A;  2G6V A;  4KM0 A;  3NU0 A;  3NZB X;  4ELF A;  1DRF A;  3HJ3 A;  3F8Y A;  1RB3 A;  3FY9 X;  5U26 A;  1DR1 A;  4FGG A;  1HFQ A;  2D0K A;  4H97 A;  3FQC A;  3DL6 A;  3KGY A;  1U71 A;  2BLB A;  4RGC A;  1RX9 A;  2BLC A;  1DG7 A;  3SR5 X;  8DFR A;  2FZJ A;  1DRB A;  1RG7 A;  4H96 A;  2D5N A;  3QL3 A;  3S3V A;  3TQ9 A;  1PD8 A;  3SRW X;  1LY4 A;  2ANO A;  2W3A A;  1RH3 A;  4PDJ A;  1RX2 A;  3KY8 A;  3FRD X;  4P3R A;  5U27 A;  4XT6 A;  4ELH A;  5FDA A;  1DAJ A;  2JYB A;  1D1G A;  4QJC A;  4KNE A;  3NXY A;  4KM2 A;  3NZA X;  1DHF A;  3QYL A;  4H98 A;  4DFR A;  6DFR A;  1J3K A;  2C2T A;  3GHV A;  3JWM A;  1DLS A;  3TD8 A;  1DR6 A;  1OHK A;  3R33 A;  3EEM A;  4HOF A;  2W9H A;  5HQY A;  3GYF A;  1RX5 A;  4QJZ D;  4ELG A;  1J3I A;  2BLA A;  1RA8 A;  1DYI A;  3KFY A;  4LAH X;  1DRA A;  3SRU X;  3K2H A;  3F0U X;  4PST A;  4G8Z X;  3E0B A;  3ZPC A;  3JWF A; 
#chains in the Genus database with same CATH homology
 3S7A A;  3NXR A;  1IA2 A;  1KMV A;  4EIL A;  3GI2 A;  3K74 A;  4M7U A;  3FRF X;  3SA2 A;  1IA1 A;  3IRN A;  3IA4 A;  1E26 A;  4NX7 A;  1DIS A;  1RF7 A;  3QLS A;  3ROA A;  3JW5 A;  3IX9 A;  4ELE A;  1DR4 A;  1DR2 A;  4OSG A;  3SGY A;  5DXV A;  3KJS A;  3RG9 A;  3NRR A;  3FQZ A;  1DLR A;  3CD2 A;  4XT5 A;  5JA3 A;  4P66 A;  1U72 A;  4GH8 A;  1LY3 A;  2GD9 A;  4EJ1 A;  3QLR A;  1CZ3 A;  1DIU A;  1YHO A;  2CIG A;  2C2S A;  4DDR A;  3SRS X;  5HT4 A;  3JW3 A;  4PSY A;  4EIZ A;  4X5F A;  1DR5 A;  2DRC A;  4PSS A;  4QLF A;  3FYV X;  3F8Z A;  3NZD A;  3INV A;  1S3V A;  4IXF X;  4KLX A;  3OAF A;  3FL8 A;  1DHI A;  1CD2 A;  4DPH A;  3FQF A;  1DYR A;  3Q1H A;  1HFP A;  2HQP A;  1DDR A;  3F0Q X;  5ECC A;  3CLB A;  3I3R A;  5HF0 X;  4HOE A;  2BL9 A;  4M6J A;  4M6K A;  1S3Y A;  4KL9 A;  3FRE X;  4KY4 A;  1DRH A;  2W3V A;  3FYW X;  5DFR A;  3EEJ A;  4OR7 A;  3NTZ A;  4I1N A;  1DR3 A;  1RX3 A;  5HVB A;  3FQ0 A;  7DFR A;  4KJJ A;  3TQB A;  1LUD A;  3RO9 A;  3GHW A;  3VCO A;  4PTJ A;  2HM9 A;  4X5G A;  4LAG X;  3JSU A;  2FZI A;  2HXV A;  1OHJ A;  4DPD A;  3NXO A;  3F0B X;  4P3Q A;  3GHC A;  4IXE D;  4PTH A;  3TQA A;  1RB2 A;  1JOM A;  4Q0E A;  5HSR A;  4FGH A;  1KLK A;  3DG8 A;  4XT7 A;  3JTW A;  3NZ6 X;  1ZDR A;  1S3W A;  5HF2 X;  2W3W A;  4KD7 A;  3FQV A;  4KEB A;  5HPB A;  3JWK A;  4XE6 X;  3EEK A;  1RA3 A;  4M2X A;  4HA9 A;  3M08 A;  4X5I A;  4I13 A;  2INQ A;  1VDR A;  1JUV A;  3DGA A;  1AI9 A;  1RA2 A;  2OBC A;  3UM6 A;  4IXG X;  3QL0 A;  1RA1 A;  4ELB A;  1RA9 A;  4M6L A;  3NXT A;  4QI9 A;  2W3B A;  1RD7 A;  3FS6 A;  1IA3 A;  4Q6A A;  1QZF A;  4Q0D A;  5E8Q A;  3DL5 A;  3K45 A;  1BZF A;  3L3R A;  4Q67 A;  2H2Q A;  3SRR X;  1S3U A;  3JWC A;  5CC9 A;  2QK8 A;  1RE7 A;  4EIG A;  3F0X X;  4DP3 A;  1RX7 A;  1MVT A;  4KAK A;  5HI6 A;  1SEJ A;  5HVE A;  3UM5 A;  1RX8 A;  3QYO A;  4ECK A;  5HQZ A;  4X5J A;  3SH2 A;  5CCC A;  4H95 A;  1RX4 A;  2ANQ A;  3IRO A;  4HA7 A;  3SRQ X;  2L28 A;  4G3M A;  5HT5 A;  4XT8 A;  3NXX A;  3OCH A;  3IA5 A;  1DRE A;  3DAT A;  3I8A X;  4G95 A;  4KBN A;  3HBB A;  2W9G A;  4XEC X;  4P68 A;  4XT4 A;  1DF7 A;  3QLW A;  2OIP A;  3FRB X;  3JVX A;  4CD2 A;  1U70 A;  3NXV A;  2AZN A;  2XW7 A;  1DHJ A;  1IA4 A;  4XRB A;  1AOE A;  3SA1 A;  5EAJ A;  1HFR A;  1VJ3 A;  2ITH A;  2W9T A;  3M09 A;  2CD2 A;  2O7P A;  1PDB A;  5ECX A;  4QLE A;  4HOG A;  1M79 A;  3CSE A;  1RX1 A;  3FY8 X;  4KJL A;  5HUI A;  5HSU A;  4KYA A;  3QLY A;  3F0V X;  1TDR A;  1DDS A;  1BOZ A;  1DG5 A;  4TU5 X;  2B3Z A;  3D84 X;  4KY8 A;  3NZC X;  4KJK A;  3FRA X;  3DAU A;  3EIG A;  2FZH A;  3FQO A;  3S9U A;  3SQY X;  3F0S X;  3DFR A;  1DR7 A;  3QLX A;  3SAI A;  3QG2 A;  2DHF A;  3LG4 A;  4FHB A;  4QHV A;  1PD9 A;  3F91 A;  3NZ9 X;  1M7A A;  4NX6 A;  4LAE X;  1M78 A;  3D80 A;  3QGT A;  3DRC A;  4X5H A;  5JG0 X;  2P4G A;  3KJR A;  1DYJ A;  4LEK X;  1DYH A;  2W9S A;  2ZZA A;  4KFJ A;  2KGK A;  2W3M A;  3EX8 A;  1KMS A;  4QLG A;  1RX6 A;  3ZPG A;  1J3J A;  1RC4 A;  1DG8 A;  1MVS A;  1JOL A;  3FL9 A;  3UM8 A;  3QFX A;  3TQ8 A;  3IRM A;  3CL9 A;  3QLZ A;  3EEL A;  1AO8 A;  2LF1 A;  3N0H A;  3K47 A;  4M7V A;  2G6V A;  4KM0 A;  3NU0 A;  3NZB X;  4ELF A;  1DRF A;  3HJ3 A;  3F8Y A;  1RB3 A;  3FY9 X;  5U26 A;  1DR1 A;  4FGG A;  1HFQ A;  2D0K A;  4H97 A;  3FQC A;  3DL6 A;  3KGY A;  1U71 A;  2BLB A;  4RGC A;  1RX9 A;  2BLC A;  1DG7 A;  3SR5 X;  8DFR A;  2FZJ A;  1DRB A;  1RG7 A;  4H96 A;  2D5N A;  3QL3 A;  3S3V A;  3TQ9 A;  1PD8 A;  3SRW X;  1LY4 A;  2ANO A;  2W3A A;  1RH3 A;  4PDJ A;  1RX2 A;  3KY8 A;  3FRD X;  4P3R A;  5U27 A;  4XT6 A;  4ELH A;  5FDA A;  1DAJ A;  2JYB A;  1D1G A;  4QJC A;  4KNE A;  3NXY A;  4KM2 A;  3NZA X;  1DHF A;  3QYL A;  4H98 A;  4DFR A;  6DFR A;  1J3K A;  2C2T A;  3GHV A;  3JWM A;  1DLS A;  3TD8 A;  1DR6 A;  1OHK A;  3R33 A;  3EEM A;  4HOF A;  2W9H A;  5HQY A;  3GYF A;  1RX5 A;  4QJZ D;  4ELG A;  1J3I A;  2BLA A;  1RA8 A;  1DYI A;  3KFY A;  4LAH X;  1DRA A;  3SRU X;  3K2H A;  3F0U X;  4PST A;  4G8Z X;  3E0B A;  3ZPC A;  3JWF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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