4P3QA

Room-temperature wt dhfr, time-averaged ensemble
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Dihydrofolate reductase
publication title Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR.
pubmed doi rcsb
source organism Escherichia coli
total genus 38
structure length 159
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-03-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4p3qA00
4CD2A 5U27A 4XT5A 4PTHA 3CLBA 1DG7A 1DAJA 4PDJA 4M7UA 5HQYA 4Q67A 1TDRA 2FZIA 3EIGA 5HI6A 3EX8A 1RX1A 3I3RA 2DHFA 3QLYA 1KMVA 3K47A 4KAKA 1DR4A 1DDSA 4DFRA 2BLBA 1JOMA 3DG8A 3F0SX 4M2XA 1DYRA 5HF2X 2W3WA 3FRAX 3JSUA 4ELGA 3OCHA 3IROA 1RB2A 3S7AA 5HF0X 5CC9A 4KFJA 3NXTA 3LG4A 5HVEA 3QFXA 2W9TA 1RX3A 3F0BX 4P68A 3JW5A 3UM6A 3SRWX 1S3WA 2QK8A 4KBNA 2W3BA 1DRAA 4FGHA 3FS6A 7DFRA 3JWKA 3INVA 4XT7A 4FHBA 2JYBA 4EIZA 3FQCA 2ZZAA 1DHFA 3FY9X 2CD2A 6DFRA 1LY4A 1IA3A 2W3VA 1D1GA 3FQZA 3QLZA 1RA2A 3NRRA 1RH3A 1DDRA 1RX2A 5HSRA 1KMSA 4H96A 2ANQA 3NZCX 4H98A 3E0BA 2ANOA 2C2SA 2W9HA 3FRDX 3JWFA 5FDAA 3QLSA 1U72A 2P4GA 3NZBX 1RX9A 3FREX 3SA2A 3ZPGA 4QJCA 2INQA 3HJ3A 4KEBA 3JTWA 5U26A 3K74A 4KD7A 3QG2A 1U70A 3JWCA 5HT4A 4PSYA 3GYFA 3DATA 1M79A 2CIGA 4PSTA 3I8AX 1DR3A 1MVTA 4KM0A 1DISA 2DRCA 2KGKA 1RX5A 4XECX 4XRBA 1DHJA 2W9SA 1DLRA 3SAIA 1IA4A 3GHCA 1DF7A 2W3MA 3CL9A 3SGYA 4KYAA 3F0XX 4HOFA 3IX9A 4IXGX 4Q6AA 4DP3A 3FRBX 1RA3A 1CD2A 3CD2A 4IXED 3F8ZA 4KJKA 1RA9A 4QLFA 3JVXA 3QYOA 4DDRA 1PDBA 3EEJA 4GH8A 2W9GA 3FRFX 3FQVA 4ECKA 1DLSA 3QYLA 3EEMA 5CCCA 4G95A 3JW3A 1RE7A 2O7PA 3IA5A 4P3RA 1IA1A 1J3IA 3R33A 5HT5A 1RD7A 1AOEA 3F91A 1DR6A 1JUVA 3TQBA 2G6VA 3FL9A 4H97A 4M6LA 3QGTA 4KY4A 3M08A 3N0HA 3FQOA 3IRNA 3KGYA 4LAGX 4HOEA 4PSSA 3JWMA 2FZJA 2C2TA 1RX4A 1OHJA 4XT8A 3OAFA 3FYVX 3FY8X 1HFPA 1S3VA 3M09A 4KY8A 4M6KA 3ZPCA 4RGCA 3S9UA 3FQFA 2BL9A 4G8ZX 3FQ0A 3NZAX 3UM8A 1RB3A 3D84X 3SQYX 2BLCA 1S3UA 3F0UX 3FL8A 4ELHA 3VCOA 4Q0EA 4QJZD 4Q0DA 4QLEA 3GI2A 1RC4A 4LAEX 4QHVA 1DIUA 3RG9A 1DYJA 3ROAA 2H2QA 1DG8A 1LY3A 3KJSA 2B3ZA 1RX8A 1DYIA 3UM5A 5HVBA 3IRMA 3SA1A 3F8YA 1OHKA 3L3RA 4X5IA 1DRBA 1AO8A 1DR7A 1DG5A 1DRFA 1YHOA 1DREA 3CSEA 5HPBA 2HQPA 1J3KA 3QL0A 5DXVA 3HBBA 4KM2A 4IXFX 5JA3A 8DFRA 3NZ6X 2OBCA 3SRUX 1HFQA 1ZDRA 1DRHA 1E26A 3TQAA 4EIGA 3Q1HA 4XE6X 3SRRX 5EAJA 3RO9A 4EILA 3NZDA 4X5GA 2HM9A 1DR5A 2HXVA 2GD9A 3F0QX 3KY8A 4FGGA 5ECCA 1AI9A 3TD8A 4P66A 5HQZA 1KLKA 4X5HA 2W3AA 4M7VA 1DR1A 4P3QA 3TQ8A 3NXXA 2D5NA 1M7AA 4TU5X 3QLRA 1RA8A 5E8QA 4I1NA 3D80A 3DAUA 2AZNA 4OSGA 3DL6A 3F0VX 4EJ1A 1DHIA 3DRCA 1S3YA 1PD9A 3SRSX 3IA4A 3K45A 3DGAA 3SR5X 3EEKA 4HOGA 3NTZA 1PD8A 3DFRA 5HSUA 4DPDA 2ITHA 4X5FA 2XW7A 1J3JA 4HA7A 4LEKX 1DYHA 4NX7A 1M78A 1LUDA 5ECXA 4G3MA 1IA2A 1BZFA 1VDRA 3K2HA 3NXRA 3QLWA 2BLAA 3KFYA 4I13A 4QLGA 1BOZA 4KJJA 3S3VA 3DL5A 4ELFA 1JOLA 3NXVA 4M6JA 2LF1A 4XT6A 4XT4A 4DPHA 5DFRA 3EELA 1RA1A 3QLXA 3SH2A 1DR2A 2OIPA 3NU0A 4QI9A 3GHVA 3NXOA 4HA9A 4ELEA 3NXYA 3GHWA 4PTJA 4NX6A 1SEJA 1VJ3A 4X5JA 1U71A 1QZFA 1CZ3A 4KL9A 2D0KA 4OR7A 3NZ9X 4ELBA 3KJRA 4KLXA 3TQ9A 1HFRA 2FZHA 4LAHX 3FYWX 5HUIA 1RF7A 2L28A 4KNEA 1RX6A 4H95A 4KJLA 5JG0X 1MVSA 1RG7A 1RX7A 3SRQX 3QL3A
chains in the Genus database with same CATH superfamily
4CD2A 5U27A 4XT5A 4PTHA 3CLBA 1DG7A 1DAJA 4PDJA 4M7UA 5HQYA 4Q67A 1TDRA 2FZIA 3EIGA 5HI6A 3EX8A 1RX1A 3I3RA 2DHFA 3QLYA 1KMVA 3K47A 4KAKA 1DR4A 1DDSA 4DFRA 2BLBA 1JOMA 3DG8A 3F0SX 4M2XA 1DYRA 5HF2X 2W3WA 3FRAX 3JSUA 4ELGA 3OCHA 3IROA 1RB2A 3S7AA 5HF0X 5CC9A 4KFJA 3NXTA 3LG4A 5HVEA 3QFXA 2W9TA 1RX3A 3F0BX 4P68A 3JW5A 3UM6A 3SRWX 1S3WA 2QK8A 4KBNA 2W3BA 1DRAA 4FGHA 3FS6A 7DFRA 3JWKA 3INVA 4XT7A 4FHBA 2JYBA 4EIZA 3FQCA 2ZZAA 1DHFA 3FY9X 2CD2A 6DFRA 1LY4A 1IA3A 2W3VA 1D1GA 3FQZA 3QLZA 1RA2A 3NRRA 1RH3A 1DDRA 1RX2A 5HSRA 1KMSA 4H96A 2ANQA 3NZCX 4H98A 3E0BA 2ANOA 2C2SA 2W9HA 3FRDX 3JWFA 5FDAA 3QLSA 1U72A 2P4GA 3NZBX 1RX9A 3FREX 3SA2A 3ZPGA 4QJCA 2INQA 3HJ3A 4KEBA 3JTWA 5U26A 3K74A 4KD7A 3QG2A 1U70A 3JWCA 5HT4A 4PSYA 3GYFA 3DATA 1M79A 2CIGA 4PSTA 3I8AX 1DR3A 1MVTA 4KM0A 1DISA 2DRCA 2KGKA 1RX5A 4XECX 4XRBA 1DHJA 2W9SA 1DLRA 3SAIA 1IA4A 3GHCA 1DF7A 2W3MA 3CL9A 3SGYA 4KYAA 3F0XX 4HOFA 3IX9A 4IXGX 4Q6AA 4DP3A 3FRBX 1RA3A 1CD2A 3CD2A 4IXED 3F8ZA 4KJKA 1RA9A 4QLFA 3JVXA 3QYOA 4DDRA 1PDBA 3EEJA 4GH8A 2W9GA 3FRFX 3FQVA 4ECKA 1DLSA 3QYLA 3EEMA 5CCCA 4G95A 3JW3A 1RE7A 2O7PA 3IA5A 4P3RA 1IA1A 1J3IA 3R33A 5HT5A 1RD7A 1AOEA 3F91A 1DR6A 1JUVA 3TQBA 2G6VA 3FL9A 4H97A 4M6LA 3QGTA 4KY4A 3M08A 3N0HA 3FQOA 3IRNA 3KGYA 4LAGX 4HOEA 4PSSA 3JWMA 2FZJA 2C2TA 1RX4A 1OHJA 4XT8A 3OAFA 3FYVX 3FY8X 1HFPA 1S3VA 3M09A 4KY8A 4M6KA 3ZPCA 4RGCA 3S9UA 3FQFA 2BL9A 4G8ZX 3FQ0A 3NZAX 3UM8A 1RB3A 3D84X 3SQYX 2BLCA 1S3UA 3F0UX 3FL8A 4ELHA 3VCOA 4Q0EA 4QJZD 4Q0DA 4QLEA 3GI2A 1RC4A 4LAEX 4QHVA 1DIUA 3RG9A 1DYJA 3ROAA 2H2QA 1DG8A 1LY3A 3KJSA 2B3ZA 1RX8A 1DYIA 3UM5A 5HVBA 3IRMA 3SA1A 3F8YA 1OHKA 3L3RA 4X5IA 1DRBA 1AO8A 1DR7A 1DG5A 1DRFA 1YHOA 1DREA 3CSEA 5HPBA 2HQPA 1J3KA 3QL0A 5DXVA 3HBBA 4KM2A 4IXFX 5JA3A 8DFRA 3NZ6X 2OBCA 3SRUX 1HFQA 1ZDRA 1DRHA 1E26A 3TQAA 4EIGA 3Q1HA 4XE6X 3SRRX 5EAJA 3RO9A 4EILA 3NZDA 4X5GA 2HM9A 1DR5A 2HXVA 2GD9A 3F0QX 3KY8A 4FGGA 5ECCA 1AI9A 3TD8A 4P66A 5HQZA 1KLKA 4X5HA 2W3AA 4M7VA 1DR1A 4P3QA 3TQ8A 3NXXA 2D5NA 1M7AA 4TU5X 3QLRA 1RA8A 5E8QA 4I1NA 3D80A 3DAUA 2AZNA 4OSGA 3DL6A 3F0VX 4EJ1A 1DHIA 3DRCA 1S3YA 1PD9A 3SRSX 3IA4A 3K45A 3DGAA 3SR5X 3EEKA 4HOGA 3NTZA 1PD8A 3DFRA 5HSUA 4DPDA 2ITHA 4X5FA 2XW7A 1J3JA 4HA7A 4LEKX 1DYHA 4NX7A 1M78A 1LUDA 5ECXA 4G3MA 1IA2A 1BZFA 1VDRA 3K2HA 3NXRA 3QLWA 2BLAA 3KFYA 4I13A 4QLGA 1BOZA 4KJJA 3S3VA 3DL5A 4ELFA 1JOLA 3NXVA 4M6JA 2LF1A 4XT6A 4XT4A 4DPHA 5DFRA 3EELA 1RA1A 3QLXA 3SH2A 1DR2A 2OIPA 3NU0A 4QI9A 3GHVA 3NXOA 4HA9A 4ELEA 3NXYA 3GHWA 4PTJA 4NX6A 1SEJA 1VJ3A 4X5JA 1U71A 1QZFA 1CZ3A 4KL9A 2D0KA 4OR7A 3NZ9X 4ELBA 3KJRA 4KLXA 3TQ9A 1HFRA 2FZHA 4LAHX 3FYWX 5HUIA 1RF7A 2L28A 4KNEA 1RX6A 4H95A 4KJLA 5JG0X 1MVSA 1RG7A 1RX7A 3SRQX 3QL3A
chains in the Genus database with same CATH topology
4CD2A 5U27A 4XT5A 4PTHA 3CLBA 1DG7A 1DAJA 4PDJA 4M7UA 5HQYA 4Q67A 1TDRA 2FZIA 3EIGA 5HI6A 3EX8A 1RX1A 3I3RA 2DHFA 3QLYA 1KMVA 3K47A 4KAKA 1DR4A 1DDSA 4DFRA 2BLBA 1JOMA 3DG8A 3F0SX 4M2XA 1DYRA 5HF2X 2W3WA 3FRAX 3JSUA 4ELGA 3OCHA 3IROA 1RB2A 3S7AA 5HF0X 5CC9A 4KFJA 3NXTA 3LG4A 5HVEA 3QFXA 2W9TA 1RX3A 3F0BX 4P68A 3JW5A 3UM6A 3SRWX 1S3WA 2QK8A 4KBNA 2W3BA 1DRAA 4FGHA 3FS6A 7DFRA 3JWKA 3INVA 4XT7A 4FHBA 2JYBA 4EIZA 3FQCA 2ZZAA 1DHFA 3FY9X 2CD2A 6DFRA 1LY4A 1IA3A 2W3VA 1D1GA 3FQZA 3QLZA 1RA2A 3NRRA 1RH3A 1DDRA 1RX2A 5HSRA 1KMSA 4H96A 2ANQA 3NZCX 4H98A 3E0BA 2ANOA 2C2SA 2W9HA 3FRDX 3JWFA 5FDAA 3QLSA 1U72A 2P4GA 3NZBX 1RX9A 3FREX 3SA2A 3ZPGA 4QJCA 2INQA 3HJ3A 4KEBA 3JTWA 5U26A 3K74A 4KD7A 3QG2A 1U70A 3JWCA 5HT4A 4PSYA 3GYFA 3DATA 1M79A 2CIGA 4PSTA 3I8AX 1DR3A 1MVTA 4KM0A 1DISA 2DRCA 2KGKA 1RX5A 4XECX 4XRBA 1DHJA 2W9SA 1DLRA 3SAIA 1IA4A 3GHCA 1DF7A 2W3MA 3CL9A 3SGYA 4KYAA 3F0XX 4HOFA 3IX9A 4IXGX 4Q6AA 4DP3A 3FRBX 1RA3A 1CD2A 3CD2A 4IXED 3F8ZA 4KJKA 1RA9A 4QLFA 3JVXA 3QYOA 4DDRA 1PDBA 3EEJA 4GH8A 2W9GA 3FRFX 3FQVA 4ECKA 1DLSA 3QYLA 3EEMA 5CCCA 4G95A 3JW3A 1RE7A 2O7PA 3IA5A 4P3RA 1IA1A 1J3IA 3R33A 5HT5A 1RD7A 1AOEA 3F91A 1DR6A 1JUVA 3TQBA 2G6VA 3FL9A 4H97A 4M6LA 3QGTA 4KY4A 3M08A 3N0HA 3FQOA 3IRNA 3KGYA 4LAGX 4HOEA 4PSSA 3JWMA 2FZJA 2C2TA 1RX4A 1OHJA 4XT8A 3OAFA 3FYVX 3FY8X 1HFPA 1S3VA 3M09A 4KY8A 4M6KA 3ZPCA 4RGCA 3S9UA 3FQFA 2BL9A 4G8ZX 3FQ0A 3NZAX 3UM8A 1RB3A 3D84X 3SQYX 2BLCA 1S3UA 3F0UX 3FL8A 4ELHA 3VCOA 4Q0EA 4QJZD 4Q0DA 4QLEA 3GI2A 1RC4A 4LAEX 4QHVA 1DIUA 3RG9A 1DYJA 3ROAA 2H2QA 1DG8A 1LY3A 3KJSA 2B3ZA 1RX8A 1DYIA 3UM5A 5HVBA 3IRMA 3SA1A 3F8YA 1OHKA 3L3RA 4X5IA 1DRBA 1AO8A 1DR7A 1DG5A 1DRFA 1YHOA 1DREA 3CSEA 5HPBA 2HQPA 1J3KA 3QL0A 5DXVA 3HBBA 4KM2A 4IXFX 5JA3A 8DFRA 3NZ6X 2OBCA 3SRUX 1HFQA 1ZDRA 1DRHA 1E26A 3TQAA 4EIGA 3Q1HA 4XE6X 3SRRX 5EAJA 3RO9A 4EILA 3NZDA 4X5GA 2HM9A 1DR5A 2HXVA 2GD9A 3F0QX 3KY8A 4FGGA 5ECCA 1AI9A 3TD8A 4P66A 5HQZA 1KLKA 4X5HA 2W3AA 4M7VA 1DR1A 4P3QA 3TQ8A 3NXXA 2D5NA 1M7AA 4TU5X 3QLRA 1RA8A 5E8QA 4I1NA 3D80A 3DAUA 2AZNA 4OSGA 3DL6A 3F0VX 4EJ1A 1DHIA 3DRCA 1S3YA 1PD9A 3SRSX 3IA4A 3K45A 3DGAA 3SR5X 3EEKA 4HOGA 3NTZA 1PD8A 3DFRA 5HSUA 4DPDA 2ITHA 4X5FA 2XW7A 1J3JA 4HA7A 4LEKX 1DYHA 4NX7A 1M78A 1LUDA 5ECXA 4G3MA 1IA2A 1BZFA 1VDRA 3K2HA 3NXRA 3QLWA 2BLAA 3KFYA 4I13A 4QLGA 1BOZA 4KJJA 3S3VA 3DL5A 4ELFA 1JOLA 3NXVA 4M6JA 2LF1A 4XT6A 4XT4A 4DPHA 5DFRA 3EELA 1RA1A 3QLXA 3SH2A 1DR2A 2OIPA 3NU0A 4QI9A 3GHVA 3NXOA 4HA9A 4ELEA 3NXYA 3GHWA 4PTJA 4NX6A 1SEJA 1VJ3A 4X5JA 1U71A 1QZFA 1CZ3A 4KL9A 2D0KA 4OR7A 3NZ9X 4ELBA 3KJRA 4KLXA 3TQ9A 1HFRA 2FZHA 4LAHX 3FYWX 5HUIA 1RF7A 2L28A 4KNEA 1RX6A 4H95A 4KJLA 5JG0X 1MVSA 1RG7A 1RX7A 3SRQX 3QL3A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4CD2 A;  5U27 A;  4XT5 A;  4PTH A;  3CLB A;  1DG7 A;  1DAJ A;  4PDJ A;  4M7U A;  5HQY A;  4Q67 A;  1TDR A;  2FZI A;  3EIG A;  5HI6 A;  3EX8 A;  1RX1 A;  3I3R A;  2DHF A;  3QLY A;  1KMV A;  3K47 A;  4KAK A;  1DR4 A;  1DDS A;  4DFR A;  2BLB A;  1JOM A;  3DG8 A;  3F0S X;  4M2X A;  1DYR A;  5HF2 X;  2W3W A;  3FRA X;  3JSU A;  4ELG A;  3OCH A;  3IRO A;  1RB2 A;  3S7A A;  5HF0 X;  5CC9 A;  4KFJ A;  3NXT A;  3LG4 A;  5HVE A;  3QFX A;  2W9T A;  1RX3 A;  3F0B X;  4P68 A;  3JW5 A;  3UM6 A;  3SRW X;  1S3W A;  2QK8 A;  4KBN A;  2W3B A;  1DRA A;  4FGH A;  3FS6 A;  7DFR A;  3JWK A;  3INV A;  4XT7 A;  4FHB A;  2JYB A;  4EIZ A;  3FQC A;  2ZZA A;  1DHF A;  3FY9 X;  2CD2 A;  6DFR A;  1LY4 A;  1IA3 A;  2W3V A;  1D1G A;  3FQZ A;  3QLZ A;  1RA2 A;  3NRR A;  1RH3 A;  1DDR A;  1RX2 A;  5HSR A;  1KMS A;  4H96 A;  2ANQ A;  3NZC X;  4H98 A;  3E0B A;  2ANO A;  2C2S A;  2W9H A;  3FRD X;  3JWF A;  5FDA A;  3QLS A;  1U72 A;  2P4G A;  3NZB X;  1RX9 A;  3FRE X;  3SA2 A;  3ZPG A;  4QJC A;  2INQ A;  3HJ3 A;  4KEB A;  3JTW A;  5U26 A;  3K74 A;  4KD7 A;  3QG2 A;  1U70 A;  3JWC A;  5HT4 A;  4PSY A;  3GYF A;  3DAT A;  1M79 A;  2CIG A;  4PST A;  3I8A X;  1DR3 A;  1MVT A;  4KM0 A;  1DIS A;  2DRC A;  2KGK A;  1RX5 A;  4XEC X;  4XRB A;  1DHJ A;  2W9S A;  1DLR A;  3SAI A;  1IA4 A;  3GHC A;  1DF7 A;  2W3M A;  3CL9 A;  3SGY A;  4KYA A;  3F0X X;  4HOF A;  3IX9 A;  4IXG X;  4Q6A A;  4DP3 A;  3FRB X;  1RA3 A;  1CD2 A;  3CD2 A;  4IXE D;  3F8Z A;  4KJK A;  1RA9 A;  4QLF A;  3JVX A;  3QYO A;  4DDR A;  1PDB A;  3EEJ A;  4GH8 A;  2W9G A;  3FRF X;  3FQV A;  4ECK A;  1DLS A;  3QYL A;  3EEM A;  5CCC A;  4G95 A;  3JW3 A;  1RE7 A;  2O7P A;  3IA5 A;  4P3R A;  1IA1 A;  1J3I A;  3R33 A;  5HT5 A;  1RD7 A;  1AOE A;  3F91 A;  1DR6 A;  1JUV A;  3TQB A;  2G6V A;  3FL9 A;  4H97 A;  4M6L A;  3QGT A;  4KY4 A;  3M08 A;  3N0H A;  3FQO A;  3IRN A;  3KGY A;  4LAG X;  4HOE A;  4PSS A;  3JWM A;  2FZJ A;  2C2T A;  1RX4 A;  1OHJ A;  4XT8 A;  3OAF A;  3FYV X;  3FY8 X;  1HFP A;  1S3V A;  3M09 A;  4KY8 A;  4M6K A;  3ZPC A;  4RGC A;  3S9U A;  3FQF A;  2BL9 A;  4G8Z X;  3FQ0 A;  3NZA X;  3UM8 A;  1RB3 A;  3D84 X;  3SQY X;  2BLC A;  1S3U A;  3F0U X;  3FL8 A;  4ELH A;  3VCO A;  4Q0E A;  4QJZ D;  4Q0D A;  4QLE A;  3GI2 A;  1RC4 A;  4LAE X;  4QHV A;  1DIU A;  3RG9 A;  1DYJ A;  3ROA A;  2H2Q A;  1DG8 A;  1LY3 A;  3KJS A;  2B3Z A;  1RX8 A;  1DYI A;  3UM5 A;  5HVB A;  3IRM A;  3SA1 A;  3F8Y A;  1OHK A;  3L3R A;  4X5I A;  1DRB A;  1AO8 A;  1DR7 A;  1DG5 A;  1DRF A;  1YHO A;  1DRE A;  3CSE A;  5HPB A;  2HQP A;  1J3K A;  3QL0 A;  5DXV A;  3HBB A;  4KM2 A;  4IXF X;  5JA3 A;  8DFR A;  3NZ6 X;  2OBC A;  3SRU X;  1HFQ A;  1ZDR A;  1DRH A;  1E26 A;  3TQA A;  4EIG A;  3Q1H A;  4XE6 X;  3SRR X;  5EAJ A;  3RO9 A;  4EIL A;  3NZD A;  4X5G A;  2HM9 A;  1DR5 A;  2HXV A;  2GD9 A;  3F0Q X;  3KY8 A;  4FGG A;  5ECC A;  1AI9 A;  3TD8 A;  4P66 A;  5HQZ A;  1KLK A;  4X5H A;  2W3A A;  4M7V A;  1DR1 A;  4P3Q A;  3TQ8 A;  3NXX A;  2D5N A;  1M7A A;  4TU5 X;  3QLR A;  1RA8 A;  5E8Q A;  4I1N A;  3D80 A;  3DAU A;  2AZN A;  4OSG A;  3DL6 A;  3F0V X;  4EJ1 A;  1DHI A;  3DRC A;  1S3Y A;  1PD9 A;  3SRS X;  3IA4 A;  3K45 A;  3DGA A;  3SR5 X;  3EEK A;  4HOG A;  3NTZ A;  1PD8 A;  3DFR A;  5HSU A;  4DPD A;  2ITH A;  4X5F A;  2XW7 A;  1J3J A;  4HA7 A;  4LEK X;  1DYH A;  4NX7 A;  1M78 A;  1LUD A;  5ECX A;  4G3M A;  1IA2 A;  1BZF A;  1VDR A;  3K2H A;  3NXR A;  3QLW A;  2BLA A;  3KFY A;  4I13 A;  4QLG A;  1BOZ A;  4KJJ A;  3S3V A;  3DL5 A;  4ELF A;  1JOL A;  3NXV A;  4M6J A;  2LF1 A;  4XT6 A;  4XT4 A;  4DPH A;  5DFR A;  3EEL A;  1RA1 A;  3QLX A;  3SH2 A;  1DR2 A;  2OIP A;  3NU0 A;  4QI9 A;  3GHV A;  3NXO A;  4HA9 A;  4ELE A;  3NXY A;  3GHW A;  4PTJ A;  4NX6 A;  1SEJ A;  1VJ3 A;  4X5J A;  1U71 A;  1QZF A;  1CZ3 A;  4KL9 A;  2D0K A;  4OR7 A;  3NZ9 X;  4ELB A;  3KJR A;  4KLX A;  3TQ9 A;  1HFR A;  2FZH A;  4LAH X;  3FYW X;  5HUI A;  1RF7 A;  2L28 A;  4KNE A;  1RX6 A;  4H95 A;  4KJL A;  5JG0 X;  1MVS A;  1RG7 A;  1RX7 A;  3SRQ X;  3QL3 A; 
#chains in the Genus database with same CATH topology
 4CD2 A;  5U27 A;  4XT5 A;  4PTH A;  3CLB A;  1DG7 A;  1DAJ A;  4PDJ A;  4M7U A;  5HQY A;  4Q67 A;  1TDR A;  2FZI A;  3EIG A;  5HI6 A;  3EX8 A;  1RX1 A;  3I3R A;  2DHF A;  3QLY A;  1KMV A;  3K47 A;  4KAK A;  1DR4 A;  1DDS A;  4DFR A;  2BLB A;  1JOM A;  3DG8 A;  3F0S X;  4M2X A;  1DYR A;  5HF2 X;  2W3W A;  3FRA X;  3JSU A;  4ELG A;  3OCH A;  3IRO A;  1RB2 A;  3S7A A;  5HF0 X;  5CC9 A;  4KFJ A;  3NXT A;  3LG4 A;  5HVE A;  3QFX A;  2W9T A;  1RX3 A;  3F0B X;  4P68 A;  3JW5 A;  3UM6 A;  3SRW X;  1S3W A;  2QK8 A;  4KBN A;  2W3B A;  1DRA A;  4FGH A;  3FS6 A;  7DFR A;  3JWK A;  3INV A;  4XT7 A;  4FHB A;  2JYB A;  4EIZ A;  3FQC A;  2ZZA A;  1DHF A;  3FY9 X;  2CD2 A;  6DFR A;  1LY4 A;  1IA3 A;  2W3V A;  1D1G A;  3FQZ A;  3QLZ A;  1RA2 A;  3NRR A;  1RH3 A;  1DDR A;  1RX2 A;  5HSR A;  1KMS A;  4H96 A;  2ANQ A;  3NZC X;  4H98 A;  3E0B A;  2ANO A;  2C2S A;  2W9H A;  3FRD X;  3JWF A;  5FDA A;  3QLS A;  1U72 A;  2P4G A;  3NZB X;  1RX9 A;  3FRE X;  3SA2 A;  3ZPG A;  4QJC A;  2INQ A;  3HJ3 A;  4KEB A;  3JTW A;  5U26 A;  3K74 A;  4KD7 A;  3QG2 A;  1U70 A;  3JWC A;  5HT4 A;  4PSY A;  3GYF A;  3DAT A;  1M79 A;  2CIG A;  4PST A;  3I8A X;  1DR3 A;  1MVT A;  4KM0 A;  1DIS A;  2DRC A;  2KGK A;  1RX5 A;  4XEC X;  4XRB A;  1DHJ A;  2W9S A;  1DLR A;  3SAI A;  1IA4 A;  3GHC A;  1DF7 A;  2W3M A;  3CL9 A;  3SGY A;  4KYA A;  3F0X X;  4HOF A;  3IX9 A;  4IXG X;  4Q6A A;  4DP3 A;  3FRB X;  1RA3 A;  1CD2 A;  3CD2 A;  4IXE D;  3F8Z A;  4KJK A;  1RA9 A;  4QLF A;  3JVX A;  3QYO A;  4DDR A;  1PDB A;  3EEJ A;  4GH8 A;  2W9G A;  3FRF X;  3FQV A;  4ECK A;  1DLS A;  3QYL A;  3EEM A;  5CCC A;  4G95 A;  3JW3 A;  1RE7 A;  2O7P A;  3IA5 A;  4P3R A;  1IA1 A;  1J3I A;  3R33 A;  5HT5 A;  1RD7 A;  1AOE A;  3F91 A;  1DR6 A;  1JUV A;  3TQB A;  2G6V A;  3FL9 A;  4H97 A;  4M6L A;  3QGT A;  4KY4 A;  3M08 A;  3N0H A;  3FQO A;  3IRN A;  3KGY A;  4LAG X;  4HOE A;  4PSS A;  3JWM A;  2FZJ A;  2C2T A;  1RX4 A;  1OHJ A;  4XT8 A;  3OAF A;  3FYV X;  3FY8 X;  1HFP A;  1S3V A;  3M09 A;  4KY8 A;  4M6K A;  3ZPC A;  4RGC A;  3S9U A;  3FQF A;  2BL9 A;  4G8Z X;  3FQ0 A;  3NZA X;  3UM8 A;  1RB3 A;  3D84 X;  3SQY X;  2BLC A;  1S3U A;  3F0U X;  3FL8 A;  4ELH A;  3VCO A;  4Q0E A;  4QJZ D;  4Q0D A;  4QLE A;  3GI2 A;  1RC4 A;  4LAE X;  4QHV A;  1DIU A;  3RG9 A;  1DYJ A;  3ROA A;  2H2Q A;  1DG8 A;  1LY3 A;  3KJS A;  2B3Z A;  1RX8 A;  1DYI A;  3UM5 A;  5HVB A;  3IRM A;  3SA1 A;  3F8Y A;  1OHK A;  3L3R A;  4X5I A;  1DRB A;  1AO8 A;  1DR7 A;  1DG5 A;  1DRF A;  1YHO A;  1DRE A;  3CSE A;  5HPB A;  2HQP A;  1J3K A;  3QL0 A;  5DXV A;  3HBB A;  4KM2 A;  4IXF X;  5JA3 A;  8DFR A;  3NZ6 X;  2OBC A;  3SRU X;  1HFQ A;  1ZDR A;  1DRH A;  1E26 A;  3TQA A;  4EIG A;  3Q1H A;  4XE6 X;  3SRR X;  5EAJ A;  3RO9 A;  4EIL A;  3NZD A;  4X5G A;  2HM9 A;  1DR5 A;  2HXV A;  2GD9 A;  3F0Q X;  3KY8 A;  4FGG A;  5ECC A;  1AI9 A;  3TD8 A;  4P66 A;  5HQZ A;  1KLK A;  4X5H A;  2W3A A;  4M7V A;  1DR1 A;  4P3Q A;  3TQ8 A;  3NXX A;  2D5N A;  1M7A A;  4TU5 X;  3QLR A;  1RA8 A;  5E8Q A;  4I1N A;  3D80 A;  3DAU A;  2AZN A;  4OSG A;  3DL6 A;  3F0V X;  4EJ1 A;  1DHI A;  3DRC A;  1S3Y A;  1PD9 A;  3SRS X;  3IA4 A;  3K45 A;  3DGA A;  3SR5 X;  3EEK A;  4HOG A;  3NTZ A;  1PD8 A;  3DFR A;  5HSU A;  4DPD A;  2ITH A;  4X5F A;  2XW7 A;  1J3J A;  4HA7 A;  4LEK X;  1DYH A;  4NX7 A;  1M78 A;  1LUD A;  5ECX A;  4G3M A;  1IA2 A;  1BZF A;  1VDR A;  3K2H A;  3NXR A;  3QLW A;  2BLA A;  3KFY A;  4I13 A;  4QLG A;  1BOZ A;  4KJJ A;  3S3V A;  3DL5 A;  4ELF A;  1JOL A;  3NXV A;  4M6J A;  2LF1 A;  4XT6 A;  4XT4 A;  4DPH A;  5DFR A;  3EEL A;  1RA1 A;  3QLX A;  3SH2 A;  1DR2 A;  2OIP A;  3NU0 A;  4QI9 A;  3GHV A;  3NXO A;  4HA9 A;  4ELE A;  3NXY A;  3GHW A;  4PTJ A;  4NX6 A;  1SEJ A;  1VJ3 A;  4X5J A;  1U71 A;  1QZF A;  1CZ3 A;  4KL9 A;  2D0K A;  4OR7 A;  3NZ9 X;  4ELB A;  3KJR A;  4KLX A;  3TQ9 A;  1HFR A;  2FZH A;  4LAH X;  3FYW X;  5HUI A;  1RF7 A;  2L28 A;  4KNE A;  1RX6 A;  4H95 A;  4KJL A;  5JG0 X;  1MVS A;  1RG7 A;  1RX7 A;  3SRQ X;  3QL3 A; 
#chains in the Genus database with same CATH homology
 4CD2 A;  5U27 A;  4XT5 A;  4PTH A;  3CLB A;  1DG7 A;  1DAJ A;  4PDJ A;  4M7U A;  5HQY A;  4Q67 A;  1TDR A;  2FZI A;  3EIG A;  5HI6 A;  3EX8 A;  1RX1 A;  3I3R A;  2DHF A;  3QLY A;  1KMV A;  3K47 A;  4KAK A;  1DR4 A;  1DDS A;  4DFR A;  2BLB A;  1JOM A;  3DG8 A;  3F0S X;  4M2X A;  1DYR A;  5HF2 X;  2W3W A;  3FRA X;  3JSU A;  4ELG A;  3OCH A;  3IRO A;  1RB2 A;  3S7A A;  5HF0 X;  5CC9 A;  4KFJ A;  3NXT A;  3LG4 A;  5HVE A;  3QFX A;  2W9T A;  1RX3 A;  3F0B X;  4P68 A;  3JW5 A;  3UM6 A;  3SRW X;  1S3W A;  2QK8 A;  4KBN A;  2W3B A;  1DRA A;  4FGH A;  3FS6 A;  7DFR A;  3JWK A;  3INV A;  4XT7 A;  4FHB A;  2JYB A;  4EIZ A;  3FQC A;  2ZZA A;  1DHF A;  3FY9 X;  2CD2 A;  6DFR A;  1LY4 A;  1IA3 A;  2W3V A;  1D1G A;  3FQZ A;  3QLZ A;  1RA2 A;  3NRR A;  1RH3 A;  1DDR A;  1RX2 A;  5HSR A;  1KMS A;  4H96 A;  2ANQ A;  3NZC X;  4H98 A;  3E0B A;  2ANO A;  2C2S A;  2W9H A;  3FRD X;  3JWF A;  5FDA A;  3QLS A;  1U72 A;  2P4G A;  3NZB X;  1RX9 A;  3FRE X;  3SA2 A;  3ZPG A;  4QJC A;  2INQ A;  3HJ3 A;  4KEB A;  3JTW A;  5U26 A;  3K74 A;  4KD7 A;  3QG2 A;  1U70 A;  3JWC A;  5HT4 A;  4PSY A;  3GYF A;  3DAT A;  1M79 A;  2CIG A;  4PST A;  3I8A X;  1DR3 A;  1MVT A;  4KM0 A;  1DIS A;  2DRC A;  2KGK A;  1RX5 A;  4XEC X;  4XRB A;  1DHJ A;  2W9S A;  1DLR A;  3SAI A;  1IA4 A;  3GHC A;  1DF7 A;  2W3M A;  3CL9 A;  3SGY A;  4KYA A;  3F0X X;  4HOF A;  3IX9 A;  4IXG X;  4Q6A A;  4DP3 A;  3FRB X;  1RA3 A;  1CD2 A;  3CD2 A;  4IXE D;  3F8Z A;  4KJK A;  1RA9 A;  4QLF A;  3JVX A;  3QYO A;  4DDR A;  1PDB A;  3EEJ A;  4GH8 A;  2W9G A;  3FRF X;  3FQV A;  4ECK A;  1DLS A;  3QYL A;  3EEM A;  5CCC A;  4G95 A;  3JW3 A;  1RE7 A;  2O7P A;  3IA5 A;  4P3R A;  1IA1 A;  1J3I A;  3R33 A;  5HT5 A;  1RD7 A;  1AOE A;  3F91 A;  1DR6 A;  1JUV A;  3TQB A;  2G6V A;  3FL9 A;  4H97 A;  4M6L A;  3QGT A;  4KY4 A;  3M08 A;  3N0H A;  3FQO A;  3IRN A;  3KGY A;  4LAG X;  4HOE A;  4PSS A;  3JWM A;  2FZJ A;  2C2T A;  1RX4 A;  1OHJ A;  4XT8 A;  3OAF A;  3FYV X;  3FY8 X;  1HFP A;  1S3V A;  3M09 A;  4KY8 A;  4M6K A;  3ZPC A;  4RGC A;  3S9U A;  3FQF A;  2BL9 A;  4G8Z X;  3FQ0 A;  3NZA X;  3UM8 A;  1RB3 A;  3D84 X;  3SQY X;  2BLC A;  1S3U A;  3F0U X;  3FL8 A;  4ELH A;  3VCO A;  4Q0E A;  4QJZ D;  4Q0D A;  4QLE A;  3GI2 A;  1RC4 A;  4LAE X;  4QHV A;  1DIU A;  3RG9 A;  1DYJ A;  3ROA A;  2H2Q A;  1DG8 A;  1LY3 A;  3KJS A;  2B3Z A;  1RX8 A;  1DYI A;  3UM5 A;  5HVB A;  3IRM A;  3SA1 A;  3F8Y A;  1OHK A;  3L3R A;  4X5I A;  1DRB A;  1AO8 A;  1DR7 A;  1DG5 A;  1DRF A;  1YHO A;  1DRE A;  3CSE A;  5HPB A;  2HQP A;  1J3K A;  3QL0 A;  5DXV A;  3HBB A;  4KM2 A;  4IXF X;  5JA3 A;  8DFR A;  3NZ6 X;  2OBC A;  3SRU X;  1HFQ A;  1ZDR A;  1DRH A;  1E26 A;  3TQA A;  4EIG A;  3Q1H A;  4XE6 X;  3SRR X;  5EAJ A;  3RO9 A;  4EIL A;  3NZD A;  4X5G A;  2HM9 A;  1DR5 A;  2HXV A;  2GD9 A;  3F0Q X;  3KY8 A;  4FGG A;  5ECC A;  1AI9 A;  3TD8 A;  4P66 A;  5HQZ A;  1KLK A;  4X5H A;  2W3A A;  4M7V A;  1DR1 A;  4P3Q A;  3TQ8 A;  3NXX A;  2D5N A;  1M7A A;  4TU5 X;  3QLR A;  1RA8 A;  5E8Q A;  4I1N A;  3D80 A;  3DAU A;  2AZN A;  4OSG A;  3DL6 A;  3F0V X;  4EJ1 A;  1DHI A;  3DRC A;  1S3Y A;  1PD9 A;  3SRS X;  3IA4 A;  3K45 A;  3DGA A;  3SR5 X;  3EEK A;  4HOG A;  3NTZ A;  1PD8 A;  3DFR A;  5HSU A;  4DPD A;  2ITH A;  4X5F A;  2XW7 A;  1J3J A;  4HA7 A;  4LEK X;  1DYH A;  4NX7 A;  1M78 A;  1LUD A;  5ECX A;  4G3M A;  1IA2 A;  1BZF A;  1VDR A;  3K2H A;  3NXR A;  3QLW A;  2BLA A;  3KFY A;  4I13 A;  4QLG A;  1BOZ A;  4KJJ A;  3S3V A;  3DL5 A;  4ELF A;  1JOL A;  3NXV A;  4M6J A;  2LF1 A;  4XT6 A;  4XT4 A;  4DPH A;  5DFR A;  3EEL A;  1RA1 A;  3QLX A;  3SH2 A;  1DR2 A;  2OIP A;  3NU0 A;  4QI9 A;  3GHV A;  3NXO A;  4HA9 A;  4ELE A;  3NXY A;  3GHW A;  4PTJ A;  4NX6 A;  1SEJ A;  1VJ3 A;  4X5J A;  1U71 A;  1QZF A;  1CZ3 A;  4KL9 A;  2D0K A;  4OR7 A;  3NZ9 X;  4ELB A;  3KJR A;  4KLX A;  3TQ9 A;  1HFR A;  2FZH A;  4LAH X;  3FYW X;  5HUI A;  1RF7 A;  2L28 A;  4KNE A;  1RX6 A;  4H95 A;  4KJL A;  5JG0 X;  1MVS A;  1RG7 A;  1RX7 A;  3SRQ X;  3QL3 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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