4P66A

Electrostatics of active site microenvironments of e. coli dhfr
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
159
structure length
158
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAAAGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYSFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the electrostatics of active site microenvironments along the catalytic cycle for Escherichia coli dihydrofolate reductase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Dihydrofolate reductase
total genus 41
structure length 158
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-03-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4p66A00
3OCHA 1QZFA 2DHFA 3NXXA 5ECXA 3NXTA 2W9HA 4QLEA 3SA2A 1DYRA 4HOGA 3F0UX 4XT6A 3S9UA 1DRAA 2B3ZA 3IRNA 2ZZAA 1D1GA 4KD7A 1DR4A 3SRUX 3FYVX 1J3IA 3QFXA 4XT4A 4P68A 3KY8A 3QLYA 4G3MA 3EEMA 3FRAX 3DG8A 3JW5A 8DFRA 3JTWA 1U72A 5HVEA 4ELGA 1S3YA 3QLWA 4KNEA 1DHFA 1JOMA 1DRFA 4OR7A 3FL8A 3EX8A 3N0HA 2D0KA 2O7PA 3IA5A 3NZDA 4KL9A 1DLRA 1DRHA 1RX2A 4M6JA 3SRQX 4X5HA 3FYWX 3GHVA 3NZAX 1DR7A 3F91A 1DRBA 4RGCA 1IA3A 3FREX 1BZFA 4KM2A 3SA1A 4XT5A 1JUVA 2BLCA 3DRCA 1S3VA 2GD9A 1TDRA 2W9GA 3FQFA 1RX1A 1IA1A 4LAGX 5DFRA 3ZPGA 5DXVA 4PSYA 1M78A 2FZHA 1ZDRA 1DYIA 5HI6A 1PDBA 2OBCA 5E8QA 4XT8A 1RX9A 4FGGA 3EIGA 3NRRA 1AOEA 5HF2X 3QLZA 5FDAA 1OHJA 3NZ6X 3NZBX 4EIZA 3TQBA 3EELA 4P3QA 4FHBA 3I8AX 4KJLA 1DR1A 3JWMA 3FL9A 3JVXA 3RO9A 3CL9A 3FQVA 3M09A 3FQZA 1DYHA 3KJRA 2H2QA 1RX3A 1RB2A 3EEKA 3DAUA 1DR5A 2C2TA 4X5FA 1VJ3A 4EJ1A 1RA9A 1HFRA 2W3VA 3GHWA 3GI2A 1YHOA 1SEJA 3SRWX 3IROA 4CD2A 3L3RA 3SAIA 1DF7A 3KFYA 4QLFA 4IXGX 3SR5X 4M2XA 3E0BA 1RB3A 1RX6A 1S3UA 4ELFA 4M6LA 4P3RA 2XW7A 1RA1A 3QL0A 3TQ8A 4QI9A 3JW3A 2ANOA 5JG0X 3CD2A 3SH2A 3DL6A 4IXED 1DG8A 4ELBA 4DDRA 1U71A 4FGHA 5HQYA 2ITHA 2BLBA 2HQPA 4H98A 4G8ZX 3TQAA 3HBBA 2CIGA 3Q1HA 2BL9A 1KMVA 1CD2A 1IA2A 5CC9A 4M7UA 3D84X 2C2SA 3VCOA 3IRMA 4DP3A 1RA3A 4KEBA 4HOFA 1DREA 1J3JA 3FS6A 2P4GA 4PTJA 3D80A 4I13A 3FRDX 4H95A 1MVTA 4I1NA 3DATA 3F0VX 4PSTA 4Q67A 3JWCA 4X5JA 1DISA 3LG4A 2HM9A 3SRSX 2W3MA 2BLAA 3NZCX 1LY3A 4QJCA 3QG2A 3DFRA 4GH8A 4OSGA 4XRBA 4XECX 3IA4A 3EEJA 1RX5A 3DL5A 1RD7A 3NU0A 2OIPA 5HT5A 3DGAA 3OAFA 5EAJA 5U27A 1DAJA 4HOEA 5HUIA 3NXOA 3QGTA 1J3KA 1DLSA 2CD2A 5HT4A 1RG7A 3JWFA 4KJKA 2INQA 5ECCA 1RH3A 3UM5A 1E26A 1DDRA 5HQZA 4DPHA 3KJSA 4PSSA 1VDRA 3FRBX 3QLXA 2W9TA 3NXYA 3INVA 1LY4A 1OHKA 3UM6A 4Q6AA 1JOLA 4IXFX 1M79A 4G95A 6DFRA 1IA4A 3IX9A 4NX6A 4X5IA 2KGKA 4H96A 4P66A 2JYBA 1DG7A 1PD8A 4NX7A 5HPBA 2W3WA 1DR3A 3CSEA 3R33A 1RX7A 3QL3A 2HXVA 1AO8A 4TU5X 3F8YA 1LUDA 3K47A 3QLRA 4Q0DA 4ELHA 1DIUA 4LAEX 1DR6A 1CZ3A 3GYFA 4DPDA 7DFRA 1MVSA 4XE6X 4KM0A 4QJZD 1S3WA 3I3RA 4H97A 2G6VA 2D5NA 3F0XX 4PDJA 3S7AA 4XT7A 2L28A 4PTHA 4M6KA 4QLGA 5JA3A 4HA7A 2QK8A 5HVBA 2DRCA 2FZIA 3KGYA 4KBNA 3QLSA 2FZJA 1DG5A 3ZPCA 1RX4A 1RX8A 4LAHX 4ELEA 3NZ9X 2ANQA 3TQ9A 1BOZA 3SGYA 4KJJA 4KY8A 1RC4A 1DR2A 4KY4A 3NTZA 2W3AA 1RA8A 2LF1A 4KYAA 1M7AA 4HA9A 3F0BX 5HF0X 4ECKA 1RF7A 4M7VA 3SRRX 1AI9A 4KAKA 4KFJA 3GHCA 3FQOA 3ROAA 3HJ3A 1U70A 1RE7A 3CLBA 3JWKA 3NXRA 3F0SX 3JSUA 3UM8A 1DHIA 3K2HA 3FQCA 4EILA 2W9SA 4KLXA 2W3BA 3K45A 5HSRA 2AZNA 3QYLA 4Q0EA 3FRFX 1PD9A 3NXVA 1DHJA 5HSUA 1DYJA 3S3VA 3FY8X 1HFQA 3TD8A 3FQ0A 4X5GA 4DFRA 1RA2A 1HFPA 4EIGA 1KMSA 3K74A 5CCCA 1KLKA 3QYOA 3RG9A 3SQYX 1DDSA 3F0QX 5U26A 4QHVA 4LEKX 3F8ZA 3FY9X 3M08A
chains in the Genus database with same CATH superfamily
3OCHA 1QZFA 2DHFA 3NXXA 5ECXA 3NXTA 2W9HA 4QLEA 3SA2A 1DYRA 4HOGA 3F0UX 4XT6A 3S9UA 1DRAA 2B3ZA 3IRNA 2ZZAA 1D1GA 4KD7A 1DR4A 3SRUX 3FYVX 1J3IA 3QFXA 4XT4A 4P68A 3KY8A 3QLYA 4G3MA 3EEMA 3FRAX 3DG8A 3JW5A 8DFRA 3JTWA 1U72A 5HVEA 4ELGA 1S3YA 3QLWA 4KNEA 1DHFA 1JOMA 1DRFA 4OR7A 3FL8A 3EX8A 3N0HA 2D0KA 2O7PA 3IA5A 3NZDA 4KL9A 1DLRA 1DRHA 1RX2A 4M6JA 3SRQX 4X5HA 3FYWX 3GHVA 3NZAX 1DR7A 3F91A 1DRBA 4RGCA 1IA3A 3FREX 1BZFA 4KM2A 3SA1A 4XT5A 1JUVA 2BLCA 3DRCA 1S3VA 2GD9A 1TDRA 2W9GA 3FQFA 1RX1A 1IA1A 4LAGX 5DFRA 3ZPGA 5DXVA 4PSYA 1M78A 2FZHA 1ZDRA 1DYIA 5HI6A 1PDBA 2OBCA 5E8QA 4XT8A 1RX9A 4FGGA 3EIGA 3NRRA 1AOEA 5HF2X 3QLZA 5FDAA 1OHJA 3NZ6X 3NZBX 4EIZA 3TQBA 3EELA 4P3QA 4FHBA 3I8AX 4KJLA 1DR1A 3JWMA 3FL9A 3JVXA 3RO9A 3CL9A 3FQVA 3M09A 3FQZA 1DYHA 3KJRA 2H2QA 1RX3A 1RB2A 3EEKA 3DAUA 1DR5A 2C2TA 4X5FA 1VJ3A 4EJ1A 1RA9A 1HFRA 2W3VA 3GHWA 3GI2A 1YHOA 1SEJA 3SRWX 3IROA 4CD2A 3L3RA 3SAIA 1DF7A 3KFYA 4QLFA 4IXGX 3SR5X 4M2XA 3E0BA 1RB3A 1RX6A 1S3UA 4ELFA 4M6LA 4P3RA 2XW7A 1RA1A 3QL0A 3TQ8A 4QI9A 3JW3A 2ANOA 5JG0X 3CD2A 3SH2A 3DL6A 4IXED 1DG8A 4ELBA 4DDRA 1U71A 4FGHA 5HQYA 2ITHA 2BLBA 2HQPA 4H98A 4G8ZX 3TQAA 3HBBA 2CIGA 3Q1HA 2BL9A 1KMVA 1CD2A 1IA2A 5CC9A 4M7UA 3D84X 2C2SA 3VCOA 3IRMA 4DP3A 1RA3A 4KEBA 4HOFA 1DREA 1J3JA 3FS6A 2P4GA 4PTJA 3D80A 4I13A 3FRDX 4H95A 1MVTA 4I1NA 3DATA 3F0VX 4PSTA 4Q67A 3JWCA 4X5JA 1DISA 3LG4A 2HM9A 3SRSX 2W3MA 2BLAA 3NZCX 1LY3A 4QJCA 3QG2A 3DFRA 4GH8A 4OSGA 4XRBA 4XECX 3IA4A 3EEJA 1RX5A 3DL5A 1RD7A 3NU0A 2OIPA 5HT5A 3DGAA 3OAFA 5EAJA 5U27A 1DAJA 4HOEA 5HUIA 3NXOA 3QGTA 1J3KA 1DLSA 2CD2A 5HT4A 1RG7A 3JWFA 4KJKA 2INQA 5ECCA 1RH3A 3UM5A 1E26A 1DDRA 5HQZA 4DPHA 3KJSA 4PSSA 1VDRA 3FRBX 3QLXA 2W9TA 3NXYA 3INVA 1LY4A 1OHKA 3UM6A 4Q6AA 1JOLA 4IXFX 1M79A 4G95A 6DFRA 1IA4A 3IX9A 4NX6A 4X5IA 2KGKA 4H96A 4P66A 2JYBA 1DG7A 1PD8A 4NX7A 5HPBA 2W3WA 1DR3A 3CSEA 3R33A 1RX7A 3QL3A 2HXVA 1AO8A 4TU5X 3F8YA 1LUDA 3K47A 3QLRA 4Q0DA 4ELHA 1DIUA 4LAEX 1DR6A 1CZ3A 3GYFA 4DPDA 7DFRA 1MVSA 4XE6X 4KM0A 4QJZD 1S3WA 3I3RA 4H97A 2G6VA 2D5NA 3F0XX 4PDJA 3S7AA 4XT7A 2L28A 4PTHA 4M6KA 4QLGA 5JA3A 4HA7A 2QK8A 5HVBA 2DRCA 2FZIA 3KGYA 4KBNA 3QLSA 2FZJA 1DG5A 3ZPCA 1RX4A 1RX8A 4LAHX 4ELEA 3NZ9X 2ANQA 3TQ9A 1BOZA 3SGYA 4KJJA 4KY8A 1RC4A 1DR2A 4KY4A 3NTZA 2W3AA 1RA8A 2LF1A 4KYAA 1M7AA 4HA9A 3F0BX 5HF0X 4ECKA 1RF7A 4M7VA 3SRRX 1AI9A 4KAKA 4KFJA 3GHCA 3FQOA 3ROAA 3HJ3A 1U70A 1RE7A 3CLBA 3JWKA 3NXRA 3F0SX 3JSUA 3UM8A 1DHIA 3K2HA 3FQCA 4EILA 2W9SA 4KLXA 2W3BA 3K45A 5HSRA 2AZNA 3QYLA 4Q0EA 3FRFX 1PD9A 3NXVA 1DHJA 5HSUA 1DYJA 3S3VA 3FY8X 1HFQA 3TD8A 3FQ0A 4X5GA 4DFRA 1RA2A 1HFPA 4EIGA 1KMSA 3K74A 5CCCA 1KLKA 3QYOA 3RG9A 3SQYX 1DDSA 3F0QX 5U26A 4QHVA 4LEKX 3F8ZA 3FY9X 3M08A
chains in the Genus database with same CATH topology
3OCHA 1QZFA 2DHFA 3NXXA 5ECXA 3NXTA 2W9HA 4QLEA 3SA2A 1DYRA 4HOGA 3F0UX 4XT6A 3S9UA 1DRAA 2B3ZA 3IRNA 2ZZAA 1D1GA 4KD7A 1DR4A 3SRUX 3FYVX 1J3IA 3QFXA 4XT4A 4P68A 3KY8A 3QLYA 4G3MA 3EEMA 3FRAX 3DG8A 3JW5A 8DFRA 3JTWA 1U72A 5HVEA 4ELGA 1S3YA 3QLWA 4KNEA 1DHFA 1JOMA 1DRFA 4OR7A 3FL8A 3EX8A 3N0HA 2D0KA 2O7PA 3IA5A 3NZDA 4KL9A 1DLRA 1DRHA 1RX2A 4M6JA 3SRQX 4X5HA 3FYWX 3GHVA 3NZAX 1DR7A 3F91A 1DRBA 4RGCA 1IA3A 3FREX 1BZFA 4KM2A 3SA1A 4XT5A 1JUVA 2BLCA 3DRCA 1S3VA 2GD9A 1TDRA 2W9GA 3FQFA 1RX1A 1IA1A 4LAGX 5DFRA 3ZPGA 5DXVA 4PSYA 1M78A 2FZHA 1ZDRA 1DYIA 5HI6A 1PDBA 2OBCA 5E8QA 4XT8A 1RX9A 4FGGA 3EIGA 3NRRA 1AOEA 5HF2X 3QLZA 5FDAA 1OHJA 3NZ6X 3NZBX 4EIZA 3TQBA 3EELA 4P3QA 4FHBA 3I8AX 4KJLA 1DR1A 3JWMA 3FL9A 3JVXA 3RO9A 3CL9A 3FQVA 3M09A 3FQZA 1DYHA 3KJRA 2H2QA 1RX3A 1RB2A 3EEKA 3DAUA 1DR5A 2C2TA 4X5FA 1VJ3A 4EJ1A 1RA9A 1HFRA 2W3VA 3GHWA 3GI2A 1YHOA 1SEJA 3SRWX 3IROA 4CD2A 3L3RA 3SAIA 1DF7A 3KFYA 4QLFA 4IXGX 3SR5X 4M2XA 3E0BA 1RB3A 1RX6A 1S3UA 4ELFA 4M6LA 4P3RA 2XW7A 1RA1A 3QL0A 3TQ8A 4QI9A 3JW3A 2ANOA 5JG0X 3CD2A 3SH2A 3DL6A 4IXED 1DG8A 4ELBA 4DDRA 1U71A 4FGHA 5HQYA 2ITHA 2BLBA 2HQPA 4H98A 4G8ZX 3TQAA 3HBBA 2CIGA 3Q1HA 2BL9A 1KMVA 1CD2A 1IA2A 5CC9A 4M7UA 3D84X 2C2SA 3VCOA 3IRMA 4DP3A 1RA3A 4KEBA 4HOFA 1DREA 1J3JA 3FS6A 2P4GA 4PTJA 3D80A 4I13A 3FRDX 4H95A 1MVTA 4I1NA 3DATA 3F0VX 4PSTA 4Q67A 3JWCA 4X5JA 1DISA 3LG4A 2HM9A 3SRSX 2W3MA 2BLAA 3NZCX 1LY3A 4QJCA 3QG2A 3DFRA 4GH8A 4OSGA 4XRBA 4XECX 3IA4A 3EEJA 1RX5A 3DL5A 1RD7A 3NU0A 2OIPA 5HT5A 3DGAA 3OAFA 5EAJA 5U27A 1DAJA 4HOEA 5HUIA 3NXOA 3QGTA 1J3KA 1DLSA 2CD2A 5HT4A 1RG7A 3JWFA 4KJKA 2INQA 5ECCA 1RH3A 3UM5A 1E26A 1DDRA 5HQZA 4DPHA 3KJSA 4PSSA 1VDRA 3FRBX 3QLXA 2W9TA 3NXYA 3INVA 1LY4A 1OHKA 3UM6A 4Q6AA 1JOLA 4IXFX 1M79A 4G95A 6DFRA 1IA4A 3IX9A 4NX6A 4X5IA 2KGKA 4H96A 4P66A 2JYBA 1DG7A 1PD8A 4NX7A 5HPBA 2W3WA 1DR3A 3CSEA 3R33A 1RX7A 3QL3A 2HXVA 1AO8A 4TU5X 3F8YA 1LUDA 3K47A 3QLRA 4Q0DA 4ELHA 1DIUA 4LAEX 1DR6A 1CZ3A 3GYFA 4DPDA 7DFRA 1MVSA 4XE6X 4KM0A 4QJZD 1S3WA 3I3RA 4H97A 2G6VA 2D5NA 3F0XX 4PDJA 3S7AA 4XT7A 2L28A 4PTHA 4M6KA 4QLGA 5JA3A 4HA7A 2QK8A 5HVBA 2DRCA 2FZIA 3KGYA 4KBNA 3QLSA 2FZJA 1DG5A 3ZPCA 1RX4A 1RX8A 4LAHX 4ELEA 3NZ9X 2ANQA 3TQ9A 1BOZA 3SGYA 4KJJA 4KY8A 1RC4A 1DR2A 4KY4A 3NTZA 2W3AA 1RA8A 2LF1A 4KYAA 1M7AA 4HA9A 3F0BX 5HF0X 4ECKA 1RF7A 4M7VA 3SRRX 1AI9A 4KAKA 4KFJA 3GHCA 3FQOA 3ROAA 3HJ3A 1U70A 1RE7A 3CLBA 3JWKA 3NXRA 3F0SX 3JSUA 3UM8A 1DHIA 3K2HA 3FQCA 4EILA 2W9SA 4KLXA 2W3BA 3K45A 5HSRA 2AZNA 3QYLA 4Q0EA 3FRFX 1PD9A 3NXVA 1DHJA 5HSUA 1DYJA 3S3VA 3FY8X 1HFQA 3TD8A 3FQ0A 4X5GA 4DFRA 1RA2A 1HFPA 4EIGA 1KMSA 3K74A 5CCCA 1KLKA 3QYOA 3RG9A 3SQYX 1DDSA 3F0QX 5U26A 4QHVA 4LEKX 3F8ZA 3FY9X 3M08A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OCH A;  1QZF A;  2DHF A;  3NXX A;  5ECX A;  3NXT A;  2W9H A;  4QLE A;  3SA2 A;  1DYR A;  4HOG A;  3F0U X;  4XT6 A;  3S9U A;  1DRA A;  2B3Z A;  3IRN A;  2ZZA A;  1D1G A;  4KD7 A;  1DR4 A;  3SRU X;  3FYV X;  1J3I A;  3QFX A;  4XT4 A;  4P68 A;  3KY8 A;  3QLY A;  4G3M A;  3EEM A;  3FRA X;  3DG8 A;  3JW5 A;  8DFR A;  3JTW A;  1U72 A;  5HVE A;  4ELG A;  1S3Y A;  3QLW A;  4KNE A;  1DHF A;  1JOM A;  1DRF A;  4OR7 A;  3FL8 A;  3EX8 A;  3N0H A;  2D0K A;  2O7P A;  3IA5 A;  3NZD A;  4KL9 A;  1DLR A;  1DRH A;  1RX2 A;  4M6J A;  3SRQ X;  4X5H A;  3FYW X;  3GHV A;  3NZA X;  1DR7 A;  3F91 A;  1DRB A;  4RGC A;  1IA3 A;  3FRE X;  1BZF A;  4KM2 A;  3SA1 A;  4XT5 A;  1JUV A;  2BLC A;  3DRC A;  1S3V A;  2GD9 A;  1TDR A;  2W9G A;  3FQF A;  1RX1 A;  1IA1 A;  4LAG X;  5DFR A;  3ZPG A;  5DXV A;  4PSY A;  1M78 A;  2FZH A;  1ZDR A;  1DYI A;  5HI6 A;  1PDB A;  2OBC A;  5E8Q A;  4XT8 A;  1RX9 A;  4FGG A;  3EIG A;  3NRR A;  1AOE A;  5HF2 X;  3QLZ A;  5FDA A;  1OHJ A;  3NZ6 X;  3NZB X;  4EIZ A;  3TQB A;  3EEL A;  4P3Q A;  4FHB A;  3I8A X;  4KJL A;  1DR1 A;  3JWM A;  3FL9 A;  3JVX A;  3RO9 A;  3CL9 A;  3FQV A;  3M09 A;  3FQZ A;  1DYH A;  3KJR A;  2H2Q A;  1RX3 A;  1RB2 A;  3EEK A;  3DAU A;  1DR5 A;  2C2T A;  4X5F A;  1VJ3 A;  4EJ1 A;  1RA9 A;  1HFR A;  2W3V A;  3GHW A;  3GI2 A;  1YHO A;  1SEJ A;  3SRW X;  3IRO A;  4CD2 A;  3L3R A;  3SAI A;  1DF7 A;  3KFY A;  4QLF A;  4IXG X;  3SR5 X;  4M2X A;  3E0B A;  1RB3 A;  1RX6 A;  1S3U A;  4ELF A;  4M6L A;  4P3R A;  2XW7 A;  1RA1 A;  3QL0 A;  3TQ8 A;  4QI9 A;  3JW3 A;  2ANO A;  5JG0 X;  3CD2 A;  3SH2 A;  3DL6 A;  4IXE D;  1DG8 A;  4ELB A;  4DDR A;  1U71 A;  4FGH A;  5HQY A;  2ITH A;  2BLB A;  2HQP A;  4H98 A;  4G8Z X;  3TQA A;  3HBB A;  2CIG A;  3Q1H A;  2BL9 A;  1KMV A;  1CD2 A;  1IA2 A;  5CC9 A;  4M7U A;  3D84 X;  2C2S A;  3VCO A;  3IRM A;  4DP3 A;  1RA3 A;  4KEB A;  4HOF A;  1DRE A;  1J3J A;  3FS6 A;  2P4G A;  4PTJ A;  3D80 A;  4I13 A;  3FRD X;  4H95 A;  1MVT A;  4I1N A;  3DAT A;  3F0V X;  4PST A;  4Q67 A;  3JWC A;  4X5J A;  1DIS A;  3LG4 A;  2HM9 A;  3SRS X;  2W3M A;  2BLA A;  3NZC X;  1LY3 A;  4QJC A;  3QG2 A;  3DFR A;  4GH8 A;  4OSG A;  4XRB A;  4XEC X;  3IA4 A;  3EEJ A;  1RX5 A;  3DL5 A;  1RD7 A;  3NU0 A;  2OIP A;  5HT5 A;  3DGA A;  3OAF A;  5EAJ A;  5U27 A;  1DAJ A;  4HOE A;  5HUI A;  3NXO A;  3QGT A;  1J3K A;  1DLS A;  2CD2 A;  5HT4 A;  1RG7 A;  3JWF A;  4KJK A;  2INQ A;  5ECC A;  1RH3 A;  3UM5 A;  1E26 A;  1DDR A;  5HQZ A;  4DPH A;  3KJS A;  4PSS A;  1VDR A;  3FRB X;  3QLX A;  2W9T A;  3NXY A;  3INV A;  1LY4 A;  1OHK A;  3UM6 A;  4Q6A A;  1JOL A;  4IXF X;  1M79 A;  4G95 A;  6DFR A;  1IA4 A;  3IX9 A;  4NX6 A;  4X5I A;  2KGK A;  4H96 A;  4P66 A;  2JYB A;  1DG7 A;  1PD8 A;  4NX7 A;  5HPB A;  2W3W A;  1DR3 A;  3CSE A;  3R33 A;  1RX7 A;  3QL3 A;  2HXV A;  1AO8 A;  4TU5 X;  3F8Y A;  1LUD A;  3K47 A;  3QLR A;  4Q0D A;  4ELH A;  1DIU A;  4LAE X;  1DR6 A;  1CZ3 A;  3GYF A;  4DPD A;  7DFR A;  1MVS A;  4XE6 X;  4KM0 A;  4QJZ D;  1S3W A;  3I3R A;  4H97 A;  2G6V A;  2D5N A;  3F0X X;  4PDJ A;  3S7A A;  4XT7 A;  2L28 A;  4PTH A;  4M6K A;  4QLG A;  5JA3 A;  4HA7 A;  2QK8 A;  5HVB A;  2DRC A;  2FZI A;  3KGY A;  4KBN A;  3QLS A;  2FZJ A;  1DG5 A;  3ZPC A;  1RX4 A;  1RX8 A;  4LAH X;  4ELE A;  3NZ9 X;  2ANQ A;  3TQ9 A;  1BOZ A;  3SGY A;  4KJJ A;  4KY8 A;  1RC4 A;  1DR2 A;  4KY4 A;  3NTZ A;  2W3A A;  1RA8 A;  2LF1 A;  4KYA A;  1M7A A;  4HA9 A;  3F0B X;  5HF0 X;  4ECK A;  1RF7 A;  4M7V A;  3SRR X;  1AI9 A;  4KAK A;  4KFJ A;  3GHC A;  3FQO A;  3ROA A;  3HJ3 A;  1U70 A;  1RE7 A;  3CLB A;  3JWK A;  3NXR A;  3F0S X;  3JSU A;  3UM8 A;  1DHI A;  3K2H A;  3FQC A;  4EIL A;  2W9S A;  4KLX A;  2W3B A;  3K45 A;  5HSR A;  2AZN A;  3QYL A;  4Q0E A;  3FRF X;  1PD9 A;  3NXV A;  1DHJ A;  5HSU A;  1DYJ A;  3S3V A;  3FY8 X;  1HFQ A;  3TD8 A;  3FQ0 A;  4X5G A;  4DFR A;  1RA2 A;  1HFP A;  4EIG A;  1KMS A;  3K74 A;  5CCC A;  1KLK A;  3QYO A;  3RG9 A;  3SQY X;  1DDS A;  3F0Q X;  5U26 A;  4QHV A;  4LEK X;  3F8Z A;  3FY9 X;  3M08 A; 
#chains in the Genus database with same CATH topology
 3OCH A;  1QZF A;  2DHF A;  3NXX A;  5ECX A;  3NXT A;  2W9H A;  4QLE A;  3SA2 A;  1DYR A;  4HOG A;  3F0U X;  4XT6 A;  3S9U A;  1DRA A;  2B3Z A;  3IRN A;  2ZZA A;  1D1G A;  4KD7 A;  1DR4 A;  3SRU X;  3FYV X;  1J3I A;  3QFX A;  4XT4 A;  4P68 A;  3KY8 A;  3QLY A;  4G3M A;  3EEM A;  3FRA X;  3DG8 A;  3JW5 A;  8DFR A;  3JTW A;  1U72 A;  5HVE A;  4ELG A;  1S3Y A;  3QLW A;  4KNE A;  1DHF A;  1JOM A;  1DRF A;  4OR7 A;  3FL8 A;  3EX8 A;  3N0H A;  2D0K A;  2O7P A;  3IA5 A;  3NZD A;  4KL9 A;  1DLR A;  1DRH A;  1RX2 A;  4M6J A;  3SRQ X;  4X5H A;  3FYW X;  3GHV A;  3NZA X;  1DR7 A;  3F91 A;  1DRB A;  4RGC A;  1IA3 A;  3FRE X;  1BZF A;  4KM2 A;  3SA1 A;  4XT5 A;  1JUV A;  2BLC A;  3DRC A;  1S3V A;  2GD9 A;  1TDR A;  2W9G A;  3FQF A;  1RX1 A;  1IA1 A;  4LAG X;  5DFR A;  3ZPG A;  5DXV A;  4PSY A;  1M78 A;  2FZH A;  1ZDR A;  1DYI A;  5HI6 A;  1PDB A;  2OBC A;  5E8Q A;  4XT8 A;  1RX9 A;  4FGG A;  3EIG A;  3NRR A;  1AOE A;  5HF2 X;  3QLZ A;  5FDA A;  1OHJ A;  3NZ6 X;  3NZB X;  4EIZ A;  3TQB A;  3EEL A;  4P3Q A;  4FHB A;  3I8A X;  4KJL A;  1DR1 A;  3JWM A;  3FL9 A;  3JVX A;  3RO9 A;  3CL9 A;  3FQV A;  3M09 A;  3FQZ A;  1DYH A;  3KJR A;  2H2Q A;  1RX3 A;  1RB2 A;  3EEK A;  3DAU A;  1DR5 A;  2C2T A;  4X5F A;  1VJ3 A;  4EJ1 A;  1RA9 A;  1HFR A;  2W3V A;  3GHW A;  3GI2 A;  1YHO A;  1SEJ A;  3SRW X;  3IRO A;  4CD2 A;  3L3R A;  3SAI A;  1DF7 A;  3KFY A;  4QLF A;  4IXG X;  3SR5 X;  4M2X A;  3E0B A;  1RB3 A;  1RX6 A;  1S3U A;  4ELF A;  4M6L A;  4P3R A;  2XW7 A;  1RA1 A;  3QL0 A;  3TQ8 A;  4QI9 A;  3JW3 A;  2ANO A;  5JG0 X;  3CD2 A;  3SH2 A;  3DL6 A;  4IXE D;  1DG8 A;  4ELB A;  4DDR A;  1U71 A;  4FGH A;  5HQY A;  2ITH A;  2BLB A;  2HQP A;  4H98 A;  4G8Z X;  3TQA A;  3HBB A;  2CIG A;  3Q1H A;  2BL9 A;  1KMV A;  1CD2 A;  1IA2 A;  5CC9 A;  4M7U A;  3D84 X;  2C2S A;  3VCO A;  3IRM A;  4DP3 A;  1RA3 A;  4KEB A;  4HOF A;  1DRE A;  1J3J A;  3FS6 A;  2P4G A;  4PTJ A;  3D80 A;  4I13 A;  3FRD X;  4H95 A;  1MVT A;  4I1N A;  3DAT A;  3F0V X;  4PST A;  4Q67 A;  3JWC A;  4X5J A;  1DIS A;  3LG4 A;  2HM9 A;  3SRS X;  2W3M A;  2BLA A;  3NZC X;  1LY3 A;  4QJC A;  3QG2 A;  3DFR A;  4GH8 A;  4OSG A;  4XRB A;  4XEC X;  3IA4 A;  3EEJ A;  1RX5 A;  3DL5 A;  1RD7 A;  3NU0 A;  2OIP A;  5HT5 A;  3DGA A;  3OAF A;  5EAJ A;  5U27 A;  1DAJ A;  4HOE A;  5HUI A;  3NXO A;  3QGT A;  1J3K A;  1DLS A;  2CD2 A;  5HT4 A;  1RG7 A;  3JWF A;  4KJK A;  2INQ A;  5ECC A;  1RH3 A;  3UM5 A;  1E26 A;  1DDR A;  5HQZ A;  4DPH A;  3KJS A;  4PSS A;  1VDR A;  3FRB X;  3QLX A;  2W9T A;  3NXY A;  3INV A;  1LY4 A;  1OHK A;  3UM6 A;  4Q6A A;  1JOL A;  4IXF X;  1M79 A;  4G95 A;  6DFR A;  1IA4 A;  3IX9 A;  4NX6 A;  4X5I A;  2KGK A;  4H96 A;  4P66 A;  2JYB A;  1DG7 A;  1PD8 A;  4NX7 A;  5HPB A;  2W3W A;  1DR3 A;  3CSE A;  3R33 A;  1RX7 A;  3QL3 A;  2HXV A;  1AO8 A;  4TU5 X;  3F8Y A;  1LUD A;  3K47 A;  3QLR A;  4Q0D A;  4ELH A;  1DIU A;  4LAE X;  1DR6 A;  1CZ3 A;  3GYF A;  4DPD A;  7DFR A;  1MVS A;  4XE6 X;  4KM0 A;  4QJZ D;  1S3W A;  3I3R A;  4H97 A;  2G6V A;  2D5N A;  3F0X X;  4PDJ A;  3S7A A;  4XT7 A;  2L28 A;  4PTH A;  4M6K A;  4QLG A;  5JA3 A;  4HA7 A;  2QK8 A;  5HVB A;  2DRC A;  2FZI A;  3KGY A;  4KBN A;  3QLS A;  2FZJ A;  1DG5 A;  3ZPC A;  1RX4 A;  1RX8 A;  4LAH X;  4ELE A;  3NZ9 X;  2ANQ A;  3TQ9 A;  1BOZ A;  3SGY A;  4KJJ A;  4KY8 A;  1RC4 A;  1DR2 A;  4KY4 A;  3NTZ A;  2W3A A;  1RA8 A;  2LF1 A;  4KYA A;  1M7A A;  4HA9 A;  3F0B X;  5HF0 X;  4ECK A;  1RF7 A;  4M7V A;  3SRR X;  1AI9 A;  4KAK A;  4KFJ A;  3GHC A;  3FQO A;  3ROA A;  3HJ3 A;  1U70 A;  1RE7 A;  3CLB A;  3JWK A;  3NXR A;  3F0S X;  3JSU A;  3UM8 A;  1DHI A;  3K2H A;  3FQC A;  4EIL A;  2W9S A;  4KLX A;  2W3B A;  3K45 A;  5HSR A;  2AZN A;  3QYL A;  4Q0E A;  3FRF X;  1PD9 A;  3NXV A;  1DHJ A;  5HSU A;  1DYJ A;  3S3V A;  3FY8 X;  1HFQ A;  3TD8 A;  3FQ0 A;  4X5G A;  4DFR A;  1RA2 A;  1HFP A;  4EIG A;  1KMS A;  3K74 A;  5CCC A;  1KLK A;  3QYO A;  3RG9 A;  3SQY X;  1DDS A;  3F0Q X;  5U26 A;  4QHV A;  4LEK X;  3F8Z A;  3FY9 X;  3M08 A; 
#chains in the Genus database with same CATH homology
 3OCH A;  1QZF A;  2DHF A;  3NXX A;  5ECX A;  3NXT A;  2W9H A;  4QLE A;  3SA2 A;  1DYR A;  4HOG A;  3F0U X;  4XT6 A;  3S9U A;  1DRA A;  2B3Z A;  3IRN A;  2ZZA A;  1D1G A;  4KD7 A;  1DR4 A;  3SRU X;  3FYV X;  1J3I A;  3QFX A;  4XT4 A;  4P68 A;  3KY8 A;  3QLY A;  4G3M A;  3EEM A;  3FRA X;  3DG8 A;  3JW5 A;  8DFR A;  3JTW A;  1U72 A;  5HVE A;  4ELG A;  1S3Y A;  3QLW A;  4KNE A;  1DHF A;  1JOM A;  1DRF A;  4OR7 A;  3FL8 A;  3EX8 A;  3N0H A;  2D0K A;  2O7P A;  3IA5 A;  3NZD A;  4KL9 A;  1DLR A;  1DRH A;  1RX2 A;  4M6J A;  3SRQ X;  4X5H A;  3FYW X;  3GHV A;  3NZA X;  1DR7 A;  3F91 A;  1DRB A;  4RGC A;  1IA3 A;  3FRE X;  1BZF A;  4KM2 A;  3SA1 A;  4XT5 A;  1JUV A;  2BLC A;  3DRC A;  1S3V A;  2GD9 A;  1TDR A;  2W9G A;  3FQF A;  1RX1 A;  1IA1 A;  4LAG X;  5DFR A;  3ZPG A;  5DXV A;  4PSY A;  1M78 A;  2FZH A;  1ZDR A;  1DYI A;  5HI6 A;  1PDB A;  2OBC A;  5E8Q A;  4XT8 A;  1RX9 A;  4FGG A;  3EIG A;  3NRR A;  1AOE A;  5HF2 X;  3QLZ A;  5FDA A;  1OHJ A;  3NZ6 X;  3NZB X;  4EIZ A;  3TQB A;  3EEL A;  4P3Q A;  4FHB A;  3I8A X;  4KJL A;  1DR1 A;  3JWM A;  3FL9 A;  3JVX A;  3RO9 A;  3CL9 A;  3FQV A;  3M09 A;  3FQZ A;  1DYH A;  3KJR A;  2H2Q A;  1RX3 A;  1RB2 A;  3EEK A;  3DAU A;  1DR5 A;  2C2T A;  4X5F A;  1VJ3 A;  4EJ1 A;  1RA9 A;  1HFR A;  2W3V A;  3GHW A;  3GI2 A;  1YHO A;  1SEJ A;  3SRW X;  3IRO A;  4CD2 A;  3L3R A;  3SAI A;  1DF7 A;  3KFY A;  4QLF A;  4IXG X;  3SR5 X;  4M2X A;  3E0B A;  1RB3 A;  1RX6 A;  1S3U A;  4ELF A;  4M6L A;  4P3R A;  2XW7 A;  1RA1 A;  3QL0 A;  3TQ8 A;  4QI9 A;  3JW3 A;  2ANO A;  5JG0 X;  3CD2 A;  3SH2 A;  3DL6 A;  4IXE D;  1DG8 A;  4ELB A;  4DDR A;  1U71 A;  4FGH A;  5HQY A;  2ITH A;  2BLB A;  2HQP A;  4H98 A;  4G8Z X;  3TQA A;  3HBB A;  2CIG A;  3Q1H A;  2BL9 A;  1KMV A;  1CD2 A;  1IA2 A;  5CC9 A;  4M7U A;  3D84 X;  2C2S A;  3VCO A;  3IRM A;  4DP3 A;  1RA3 A;  4KEB A;  4HOF A;  1DRE A;  1J3J A;  3FS6 A;  2P4G A;  4PTJ A;  3D80 A;  4I13 A;  3FRD X;  4H95 A;  1MVT A;  4I1N A;  3DAT A;  3F0V X;  4PST A;  4Q67 A;  3JWC A;  4X5J A;  1DIS A;  3LG4 A;  2HM9 A;  3SRS X;  2W3M A;  2BLA A;  3NZC X;  1LY3 A;  4QJC A;  3QG2 A;  3DFR A;  4GH8 A;  4OSG A;  4XRB A;  4XEC X;  3IA4 A;  3EEJ A;  1RX5 A;  3DL5 A;  1RD7 A;  3NU0 A;  2OIP A;  5HT5 A;  3DGA A;  3OAF A;  5EAJ A;  5U27 A;  1DAJ A;  4HOE A;  5HUI A;  3NXO A;  3QGT A;  1J3K A;  1DLS A;  2CD2 A;  5HT4 A;  1RG7 A;  3JWF A;  4KJK A;  2INQ A;  5ECC A;  1RH3 A;  3UM5 A;  1E26 A;  1DDR A;  5HQZ A;  4DPH A;  3KJS A;  4PSS A;  1VDR A;  3FRB X;  3QLX A;  2W9T A;  3NXY A;  3INV A;  1LY4 A;  1OHK A;  3UM6 A;  4Q6A A;  1JOL A;  4IXF X;  1M79 A;  4G95 A;  6DFR A;  1IA4 A;  3IX9 A;  4NX6 A;  4X5I A;  2KGK A;  4H96 A;  4P66 A;  2JYB A;  1DG7 A;  1PD8 A;  4NX7 A;  5HPB A;  2W3W A;  1DR3 A;  3CSE A;  3R33 A;  1RX7 A;  3QL3 A;  2HXV A;  1AO8 A;  4TU5 X;  3F8Y A;  1LUD A;  3K47 A;  3QLR A;  4Q0D A;  4ELH A;  1DIU A;  4LAE X;  1DR6 A;  1CZ3 A;  3GYF A;  4DPD A;  7DFR A;  1MVS A;  4XE6 X;  4KM0 A;  4QJZ D;  1S3W A;  3I3R A;  4H97 A;  2G6V A;  2D5N A;  3F0X X;  4PDJ A;  3S7A A;  4XT7 A;  2L28 A;  4PTH A;  4M6K A;  4QLG A;  5JA3 A;  4HA7 A;  2QK8 A;  5HVB A;  2DRC A;  2FZI A;  3KGY A;  4KBN A;  3QLS A;  2FZJ A;  1DG5 A;  3ZPC A;  1RX4 A;  1RX8 A;  4LAH X;  4ELE A;  3NZ9 X;  2ANQ A;  3TQ9 A;  1BOZ A;  3SGY A;  4KJJ A;  4KY8 A;  1RC4 A;  1DR2 A;  4KY4 A;  3NTZ A;  2W3A A;  1RA8 A;  2LF1 A;  4KYA A;  1M7A A;  4HA9 A;  3F0B X;  5HF0 X;  4ECK A;  1RF7 A;  4M7V A;  3SRR X;  1AI9 A;  4KAK A;  4KFJ A;  3GHC A;  3FQO A;  3ROA A;  3HJ3 A;  1U70 A;  1RE7 A;  3CLB A;  3JWK A;  3NXR A;  3F0S X;  3JSU A;  3UM8 A;  1DHI A;  3K2H A;  3FQC A;  4EIL A;  2W9S A;  4KLX A;  2W3B A;  3K45 A;  5HSR A;  2AZN A;  3QYL A;  4Q0E A;  3FRF X;  1PD9 A;  3NXV A;  1DHJ A;  5HSU A;  1DYJ A;  3S3V A;  3FY8 X;  1HFQ A;  3TD8 A;  3FQ0 A;  4X5G A;  4DFR A;  1RA2 A;  1HFP A;  4EIG A;  1KMS A;  3K74 A;  5CCC A;  1KLK A;  3QYO A;  3RG9 A;  3SQY X;  1DDS A;  3F0Q X;  5U26 A;  4QHV A;  4LEK X;  3F8Z A;  3FY9 X;  3M08 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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