4PSYA

100k crystal structure of escherichia coli dihydrofolate reductase
Total Genus 46
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
159
structure length
158
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Dihydrofolate reductase
total genus 46
structure length 158
sequence length 159
ec nomenclature
pdb deposition date 2014-03-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4psyA00
3QLWA 1RB2A 3QL3A 5HF0X 3QYOA 1D1GA 2BLCA 3QL0A 1JOLA 2G6VA 4XE6X 3R33A 2ZZAA 1PD9A 3F8YA 4EILA 3NZ6X 4KNEA 5HVEA 3F0SX 3NZ9X 3IRMA 3QFXA 4NX6A 4TU5X 1DISA 1SEJA 1DRAA 4DFRA 2CD2A 1LY3A 4XT5A 2D0KA 3D80A 3OCHA 4IXFX 2BL9A 1DG7A 1CD2A 3FQOA 1RX4A 4Q6AA 4IXGX 4KY4A 1RE7A 3ZPCA 2ITHA 2BLBA 1CZ3A 4PTJA 4XT8A 2OBCA 4QLGA 4I13A 4DPHA 3M09A 1OHKA 4KBNA 4OR7A 1DYJA 2W3WA 4ELFA 2W9TA 1RF7A 4LAHX 3CLBA 3FY9X 3SA1A 1QZFA 1RX8A 4G95A 3F8ZA 3KY8A 1DRBA 4PTHA 4GH8A 3FQVA 3UM6A 4H96A 3GYFA 3JWKA 3TQ9A 4HOFA 3NRRA 3CD2A 3DFRA 1YHOA 3SR5X 3FYVX 1IA3A 3EEKA 5HSUA 2AZNA 1DYRA 5E8QA 5ECCA 3FS6A 3IROA 1HFRA 3JW5A 3KGYA 3ROAA 2W3BA 2KGKA 4M6KA 3JWMA 3QLZA 1DIUA 3DG8A 3EEJA 3K2HA 4QI9A 8DFRA 4XT7A 4FHBA 3FL8A 3I8AX 3JTWA 1DF7A 1J3KA 1RD7A 3SRRX 2LF1A 1E26A 1RG7A 4HOEA 1S3YA 1S3VA 4LAGX 5JG0X 4H98A 2DHFA 4ELGA 1DHFA 3IX9A 1BZFA 4X5HA 3D84X 4XT4A 3RO9A 3Q1HA 3QLXA 1RA8A 3EIGA 1DLSA 4EIGA 3SA2A 5HPBA 3GI2A 4QLFA 3TQ8A 3JWFA 5CCCA 1DYHA 1LY4A 3FREX 1DG8A 3FQFA 3F0UX 3NZCX 3HJ3A 4X5FA 4XT6A 1OHJA 4KM0A 5HQZA 3TQBA 5HSRA 2C2SA 3M08A 1RX5A 2W9GA 3LG4A 3NXVA 1RH3A 1JUVA 1RX7A 2BLAA 1AI9A 1J3IA 4ELHA 4HA9A 1AO8A 1RX1A 3DL5A 4G3MA 1U70A 1DR4A 2INQA 2FZIA 2W9SA 1IA1A 3JVXA 2XW7A 3NXOA 4KY8A 1DR3A 3K74A 2ANOA 5HVBA 4X5IA 3GHWA 5JA3A 2ANQA 4KJJA 1HFQA 4EIZA 2OIPA 3NU0A 4PDJA 3IRNA 2D5NA 1HFPA 4P66A 4P3QA 1M78A 3SRSX 4FGHA 3VCOA 3QLSA 1RA9A 1DDSA 4H97A 1RA2A 3HBBA 2O7PA 3UM8A 4Q0DA 4KLXA 3TD8A 2W3VA 4QHVA 4FGGA 3CSEA 3DL6A 3INVA 1IA4A 3GHVA 1RX3A 2CIGA 3RG9A 4KM2A 3KJRA 3I3RA 3N0HA 4P68A 1JOMA 1BOZA 1MVTA 5HT4A 3DRCA 3FQ0A 3NTZA 1J3JA 1RX2A 4DDRA 3FRDX 3FQZA 2HXVA 5HF2X 3K47A 4I1NA 3QLYA 5U26A 3QYLA 1AOEA 2FZJA 4KJKA 3KFYA 1KLKA 2W3AA 1VJ3A 1DYIA 4QJCA 4KYAA 4KEBA 1U72A 3GHCA 4KJLA 4DPDA 3FL9A 1KMSA 3FRBX 4HOGA 1DLRA 1DR7A 3NXTA 3OAFA 5FDAA 5HQYA 4M2XA 4XRBA 3S9UA 4LEKX 3SH2A 5DXVA 1DR5A 3F0QX 3JSUA 1S3WA 1DR6A 1DHJA 2DRCA 4NX7A 4HA7A 3DGAA 3ZPGA 1DR1A 3F0BX 1PDBA 2W3MA 1RB3A 5CC9A 4PSSA 2GD9A 2H2QA 3FYWX 3E0BA 1DRHA 4IXED 3DAUA 1RX9A 3QG2A 6DFRA 3QLRA 3K45A 3TQAA 1RA3A 4DP3A 2HM9A 3UM5A 4M6JA 1RX6A 3F0XX 3IA4A 1TDRA 3DATA 4QJZD 3QGTA 2JYBA 1M7AA 1ZDRA 4ELEA 4Q0EA 2QK8A 1KMVA 3SAIA 5ECXA 1DR2A 5U27A 4KD7A 3EEMA 3S3VA 3S7AA 1S3UA 2L28A 3EELA 4RGCA 1VDRA 1RC4A 3SQYX 4KL9A 4Q67A 4X5GA 1DREA 4M7VA 3NXYA 4LAEX 4CD2A 1DRFA 3IA5A 4OSGA 2HQPA 4PSYA 3SRUX 3KJSA 4XECX 4EJ1A 4KAKA 7DFRA 4M6LA 3SRWX 4KFJA 3JW3A 3NXRA 1DDRA 3CL9A 4H95A 1DHIA 3JWCA 5HT5A 3EX8A 3F0VX 4M7UA 1M79A 2W9HA 4QLEA 5EAJA 2C2TA 4ECKA 3SGYA 4G8ZX 3FY8X 5DFRA 1MVSA 1IA2A 4ELBA 1U71A 4P3RA 3NZDA 3FRAX 2P4GA 3FRFX 1DAJA 1LUDA 3SRQX 1RA1A 3NZAX 1DG5A 2FZHA 3FQCA 1PD8A 3L3RA 3NZBX 3F91A 2B3ZA 5HUIA 5HI6A 4X5JA 3NXXA 4PSTA
chains in the Genus database with same CATH superfamily
3QLWA 1RB2A 3QL3A 5HF0X 3QYOA 1D1GA 2BLCA 3QL0A 1JOLA 2G6VA 4XE6X 3R33A 2ZZAA 1PD9A 3F8YA 4EILA 3NZ6X 4KNEA 5HVEA 3F0SX 3NZ9X 3IRMA 3QFXA 4NX6A 4TU5X 1DISA 1SEJA 1DRAA 4DFRA 2CD2A 1LY3A 4XT5A 2D0KA 3D80A 3OCHA 4IXFX 2BL9A 1DG7A 1CD2A 3FQOA 1RX4A 4Q6AA 4IXGX 4KY4A 1RE7A 3ZPCA 2ITHA 2BLBA 1CZ3A 4PTJA 4XT8A 2OBCA 4QLGA 4I13A 4DPHA 3M09A 1OHKA 4KBNA 4OR7A 1DYJA 2W3WA 4ELFA 2W9TA 1RF7A 4LAHX 3CLBA 3FY9X 3SA1A 1QZFA 1RX8A 4G95A 3F8ZA 3KY8A 1DRBA 4PTHA 4GH8A 3FQVA 3UM6A 4H96A 3GYFA 3JWKA 3TQ9A 4HOFA 3NRRA 3CD2A 3DFRA 1YHOA 3SR5X 3FYVX 1IA3A 3EEKA 5HSUA 2AZNA 1DYRA 5E8QA 5ECCA 3FS6A 3IROA 1HFRA 3JW5A 3KGYA 3ROAA 2W3BA 2KGKA 4M6KA 3JWMA 3QLZA 1DIUA 3DG8A 3EEJA 3K2HA 4QI9A 8DFRA 4XT7A 4FHBA 3FL8A 3I8AX 3JTWA 1DF7A 1J3KA 1RD7A 3SRRX 2LF1A 1E26A 1RG7A 4HOEA 1S3YA 1S3VA 4LAGX 5JG0X 4H98A 2DHFA 4ELGA 1DHFA 3IX9A 1BZFA 4X5HA 3D84X 4XT4A 3RO9A 3Q1HA 3QLXA 1RA8A 3EIGA 1DLSA 4EIGA 3SA2A 5HPBA 3GI2A 4QLFA 3TQ8A 3JWFA 5CCCA 1DYHA 1LY4A 3FREX 1DG8A 3FQFA 3F0UX 3NZCX 3HJ3A 4X5FA 4XT6A 1OHJA 4KM0A 5HQZA 3TQBA 5HSRA 2C2SA 3M08A 1RX5A 2W9GA 3LG4A 3NXVA 1RH3A 1JUVA 1RX7A 2BLAA 1AI9A 1J3IA 4ELHA 4HA9A 1AO8A 1RX1A 3DL5A 4G3MA 1U70A 1DR4A 2INQA 2FZIA 2W9SA 1IA1A 3JVXA 2XW7A 3NXOA 4KY8A 1DR3A 3K74A 2ANOA 5HVBA 4X5IA 3GHWA 5JA3A 2ANQA 4KJJA 1HFQA 4EIZA 2OIPA 3NU0A 4PDJA 3IRNA 2D5NA 1HFPA 4P66A 4P3QA 1M78A 3SRSX 4FGHA 3VCOA 3QLSA 1RA9A 1DDSA 4H97A 1RA2A 3HBBA 2O7PA 3UM8A 4Q0DA 4KLXA 3TD8A 2W3VA 4QHVA 4FGGA 3CSEA 3DL6A 3INVA 1IA4A 3GHVA 1RX3A 2CIGA 3RG9A 4KM2A 3KJRA 3I3RA 3N0HA 4P68A 1JOMA 1BOZA 1MVTA 5HT4A 3DRCA 3FQ0A 3NTZA 1J3JA 1RX2A 4DDRA 3FRDX 3FQZA 2HXVA 5HF2X 3K47A 4I1NA 3QLYA 5U26A 3QYLA 1AOEA 2FZJA 4KJKA 3KFYA 1KLKA 2W3AA 1VJ3A 1DYIA 4QJCA 4KYAA 4KEBA 1U72A 3GHCA 4KJLA 4DPDA 3FL9A 1KMSA 3FRBX 4HOGA 1DLRA 1DR7A 3NXTA 3OAFA 5FDAA 5HQYA 4M2XA 4XRBA 3S9UA 4LEKX 3SH2A 5DXVA 1DR5A 3F0QX 3JSUA 1S3WA 1DR6A 1DHJA 2DRCA 4NX7A 4HA7A 3DGAA 3ZPGA 1DR1A 3F0BX 1PDBA 2W3MA 1RB3A 5CC9A 4PSSA 2GD9A 2H2QA 3FYWX 3E0BA 1DRHA 4IXED 3DAUA 1RX9A 3QG2A 6DFRA 3QLRA 3K45A 3TQAA 1RA3A 4DP3A 2HM9A 3UM5A 4M6JA 1RX6A 3F0XX 3IA4A 1TDRA 3DATA 4QJZD 3QGTA 2JYBA 1M7AA 1ZDRA 4ELEA 4Q0EA 2QK8A 1KMVA 3SAIA 5ECXA 1DR2A 5U27A 4KD7A 3EEMA 3S3VA 3S7AA 1S3UA 2L28A 3EELA 4RGCA 1VDRA 1RC4A 3SQYX 4KL9A 4Q67A 4X5GA 1DREA 4M7VA 3NXYA 4LAEX 4CD2A 1DRFA 3IA5A 4OSGA 2HQPA 4PSYA 3SRUX 3KJSA 4XECX 4EJ1A 4KAKA 7DFRA 4M6LA 3SRWX 4KFJA 3JW3A 3NXRA 1DDRA 3CL9A 4H95A 1DHIA 3JWCA 5HT5A 3EX8A 3F0VX 4M7UA 1M79A 2W9HA 4QLEA 5EAJA 2C2TA 4ECKA 3SGYA 4G8ZX 3FY8X 5DFRA 1MVSA 1IA2A 4ELBA 1U71A 4P3RA 3NZDA 3FRAX 2P4GA 3FRFX 1DAJA 1LUDA 3SRQX 1RA1A 3NZAX 1DG5A 2FZHA 3FQCA 1PD8A 3L3RA 3NZBX 3F91A 2B3ZA 5HUIA 5HI6A 4X5JA 3NXXA 4PSTA
chains in the Genus database with same CATH topology
3QLWA 1RB2A 3QL3A 5HF0X 3QYOA 1D1GA 2BLCA 3QL0A 1JOLA 2G6VA 4XE6X 3R33A 2ZZAA 1PD9A 3F8YA 4EILA 3NZ6X 4KNEA 5HVEA 3F0SX 3NZ9X 3IRMA 3QFXA 4NX6A 4TU5X 1DISA 1SEJA 1DRAA 4DFRA 2CD2A 1LY3A 4XT5A 2D0KA 3D80A 3OCHA 4IXFX 2BL9A 1DG7A 1CD2A 3FQOA 1RX4A 4Q6AA 4IXGX 4KY4A 1RE7A 3ZPCA 2ITHA 2BLBA 1CZ3A 4PTJA 4XT8A 2OBCA 4QLGA 4I13A 4DPHA 3M09A 1OHKA 4KBNA 4OR7A 1DYJA 2W3WA 4ELFA 2W9TA 1RF7A 4LAHX 3CLBA 3FY9X 3SA1A 1QZFA 1RX8A 4G95A 3F8ZA 3KY8A 1DRBA 4PTHA 4GH8A 3FQVA 3UM6A 4H96A 3GYFA 3JWKA 3TQ9A 4HOFA 3NRRA 3CD2A 3DFRA 1YHOA 3SR5X 3FYVX 1IA3A 3EEKA 5HSUA 2AZNA 1DYRA 5E8QA 5ECCA 3FS6A 3IROA 1HFRA 3JW5A 3KGYA 3ROAA 2W3BA 2KGKA 4M6KA 3JWMA 3QLZA 1DIUA 3DG8A 3EEJA 3K2HA 4QI9A 8DFRA 4XT7A 4FHBA 3FL8A 3I8AX 3JTWA 1DF7A 1J3KA 1RD7A 3SRRX 2LF1A 1E26A 1RG7A 4HOEA 1S3YA 1S3VA 4LAGX 5JG0X 4H98A 2DHFA 4ELGA 1DHFA 3IX9A 1BZFA 4X5HA 3D84X 4XT4A 3RO9A 3Q1HA 3QLXA 1RA8A 3EIGA 1DLSA 4EIGA 3SA2A 5HPBA 3GI2A 4QLFA 3TQ8A 3JWFA 5CCCA 1DYHA 1LY4A 3FREX 1DG8A 3FQFA 3F0UX 3NZCX 3HJ3A 4X5FA 4XT6A 1OHJA 4KM0A 5HQZA 3TQBA 5HSRA 2C2SA 3M08A 1RX5A 2W9GA 3LG4A 3NXVA 1RH3A 1JUVA 1RX7A 2BLAA 1AI9A 1J3IA 4ELHA 4HA9A 1AO8A 1RX1A 3DL5A 4G3MA 1U70A 1DR4A 2INQA 2FZIA 2W9SA 1IA1A 3JVXA 2XW7A 3NXOA 4KY8A 1DR3A 3K74A 2ANOA 5HVBA 4X5IA 3GHWA 5JA3A 2ANQA 4KJJA 1HFQA 4EIZA 2OIPA 3NU0A 4PDJA 3IRNA 2D5NA 1HFPA 4P66A 4P3QA 1M78A 3SRSX 4FGHA 3VCOA 3QLSA 1RA9A 1DDSA 4H97A 1RA2A 3HBBA 2O7PA 3UM8A 4Q0DA 4KLXA 3TD8A 2W3VA 4QHVA 4FGGA 3CSEA 3DL6A 3INVA 1IA4A 3GHVA 1RX3A 2CIGA 3RG9A 4KM2A 3KJRA 3I3RA 3N0HA 4P68A 1JOMA 1BOZA 1MVTA 5HT4A 3DRCA 3FQ0A 3NTZA 1J3JA 1RX2A 4DDRA 3FRDX 3FQZA 2HXVA 5HF2X 3K47A 4I1NA 3QLYA 5U26A 3QYLA 1AOEA 2FZJA 4KJKA 3KFYA 1KLKA 2W3AA 1VJ3A 1DYIA 4QJCA 4KYAA 4KEBA 1U72A 3GHCA 4KJLA 4DPDA 3FL9A 1KMSA 3FRBX 4HOGA 1DLRA 1DR7A 3NXTA 3OAFA 5FDAA 5HQYA 4M2XA 4XRBA 3S9UA 4LEKX 3SH2A 5DXVA 1DR5A 3F0QX 3JSUA 1S3WA 1DR6A 1DHJA 2DRCA 4NX7A 4HA7A 3DGAA 3ZPGA 1DR1A 3F0BX 1PDBA 2W3MA 1RB3A 5CC9A 4PSSA 2GD9A 2H2QA 3FYWX 3E0BA 1DRHA 4IXED 3DAUA 1RX9A 3QG2A 6DFRA 3QLRA 3K45A 3TQAA 1RA3A 4DP3A 2HM9A 3UM5A 4M6JA 1RX6A 3F0XX 3IA4A 1TDRA 3DATA 4QJZD 3QGTA 2JYBA 1M7AA 1ZDRA 4ELEA 4Q0EA 2QK8A 1KMVA 3SAIA 5ECXA 1DR2A 5U27A 4KD7A 3EEMA 3S3VA 3S7AA 1S3UA 2L28A 3EELA 4RGCA 1VDRA 1RC4A 3SQYX 4KL9A 4Q67A 4X5GA 1DREA 4M7VA 3NXYA 4LAEX 4CD2A 1DRFA 3IA5A 4OSGA 2HQPA 4PSYA 3SRUX 3KJSA 4XECX 4EJ1A 4KAKA 7DFRA 4M6LA 3SRWX 4KFJA 3JW3A 3NXRA 1DDRA 3CL9A 4H95A 1DHIA 3JWCA 5HT5A 3EX8A 3F0VX 4M7UA 1M79A 2W9HA 4QLEA 5EAJA 2C2TA 4ECKA 3SGYA 4G8ZX 3FY8X 5DFRA 1MVSA 1IA2A 4ELBA 1U71A 4P3RA 3NZDA 3FRAX 2P4GA 3FRFX 1DAJA 1LUDA 3SRQX 1RA1A 3NZAX 1DG5A 2FZHA 3FQCA 1PD8A 3L3RA 3NZBX 3F91A 2B3ZA 5HUIA 5HI6A 4X5JA 3NXXA 4PSTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QLW A;  1RB2 A;  3QL3 A;  5HF0 X;  3QYO A;  1D1G A;  2BLC A;  3QL0 A;  1JOL A;  2G6V A;  4XE6 X;  3R33 A;  2ZZA A;  1PD9 A;  3F8Y A;  4EIL A;  3NZ6 X;  4KNE A;  5HVE A;  3F0S X;  3NZ9 X;  3IRM A;  3QFX A;  4NX6 A;  4TU5 X;  1DIS A;  1SEJ A;  1DRA A;  4DFR A;  2CD2 A;  1LY3 A;  4XT5 A;  2D0K A;  3D80 A;  3OCH A;  4IXF X;  2BL9 A;  1DG7 A;  1CD2 A;  3FQO A;  1RX4 A;  4Q6A A;  4IXG X;  4KY4 A;  1RE7 A;  3ZPC A;  2ITH A;  2BLB A;  1CZ3 A;  4PTJ A;  4XT8 A;  2OBC A;  4QLG A;  4I13 A;  4DPH A;  3M09 A;  1OHK A;  4KBN A;  4OR7 A;  1DYJ A;  2W3W A;  4ELF A;  2W9T A;  1RF7 A;  4LAH X;  3CLB A;  3FY9 X;  3SA1 A;  1QZF A;  1RX8 A;  4G95 A;  3F8Z A;  3KY8 A;  1DRB A;  4PTH A;  4GH8 A;  3FQV A;  3UM6 A;  4H96 A;  3GYF A;  3JWK A;  3TQ9 A;  4HOF A;  3NRR A;  3CD2 A;  3DFR A;  1YHO A;  3SR5 X;  3FYV X;  1IA3 A;  3EEK A;  5HSU A;  2AZN A;  1DYR A;  5E8Q A;  5ECC A;  3FS6 A;  3IRO A;  1HFR A;  3JW5 A;  3KGY A;  3ROA A;  2W3B A;  2KGK A;  4M6K A;  3JWM A;  3QLZ A;  1DIU A;  3DG8 A;  3EEJ A;  3K2H A;  4QI9 A;  8DFR A;  4XT7 A;  4FHB A;  3FL8 A;  3I8A X;  3JTW A;  1DF7 A;  1J3K A;  1RD7 A;  3SRR X;  2LF1 A;  1E26 A;  1RG7 A;  4HOE A;  1S3Y A;  1S3V A;  4LAG X;  5JG0 X;  4H98 A;  2DHF A;  4ELG A;  1DHF A;  3IX9 A;  1BZF A;  4X5H A;  3D84 X;  4XT4 A;  3RO9 A;  3Q1H A;  3QLX A;  1RA8 A;  3EIG A;  1DLS A;  4EIG A;  3SA2 A;  5HPB A;  3GI2 A;  4QLF A;  3TQ8 A;  3JWF A;  5CCC A;  1DYH A;  1LY4 A;  3FRE X;  1DG8 A;  3FQF A;  3F0U X;  3NZC X;  3HJ3 A;  4X5F A;  4XT6 A;  1OHJ A;  4KM0 A;  5HQZ A;  3TQB A;  5HSR A;  2C2S A;  3M08 A;  1RX5 A;  2W9G A;  3LG4 A;  3NXV A;  1RH3 A;  1JUV A;  1RX7 A;  2BLA A;  1AI9 A;  1J3I A;  4ELH A;  4HA9 A;  1AO8 A;  1RX1 A;  3DL5 A;  4G3M A;  1U70 A;  1DR4 A;  2INQ A;  2FZI A;  2W9S A;  1IA1 A;  3JVX A;  2XW7 A;  3NXO A;  4KY8 A;  1DR3 A;  3K74 A;  2ANO A;  5HVB A;  4X5I A;  3GHW A;  5JA3 A;  2ANQ A;  4KJJ A;  1HFQ A;  4EIZ A;  2OIP A;  3NU0 A;  4PDJ A;  3IRN A;  2D5N A;  1HFP A;  4P66 A;  4P3Q A;  1M78 A;  3SRS X;  4FGH A;  3VCO A;  3QLS A;  1RA9 A;  1DDS A;  4H97 A;  1RA2 A;  3HBB A;  2O7P A;  3UM8 A;  4Q0D A;  4KLX A;  3TD8 A;  2W3V A;  4QHV A;  4FGG A;  3CSE A;  3DL6 A;  3INV A;  1IA4 A;  3GHV A;  1RX3 A;  2CIG A;  3RG9 A;  4KM2 A;  3KJR A;  3I3R A;  3N0H A;  4P68 A;  1JOM A;  1BOZ A;  1MVT A;  5HT4 A;  3DRC A;  3FQ0 A;  3NTZ A;  1J3J A;  1RX2 A;  4DDR A;  3FRD X;  3FQZ A;  2HXV A;  5HF2 X;  3K47 A;  4I1N A;  3QLY A;  5U26 A;  3QYL A;  1AOE A;  2FZJ A;  4KJK A;  3KFY A;  1KLK A;  2W3A A;  1VJ3 A;  1DYI A;  4QJC A;  4KYA A;  4KEB A;  1U72 A;  3GHC A;  4KJL A;  4DPD A;  3FL9 A;  1KMS A;  3FRB X;  4HOG A;  1DLR A;  1DR7 A;  3NXT A;  3OAF A;  5FDA A;  5HQY A;  4M2X A;  4XRB A;  3S9U A;  4LEK X;  3SH2 A;  5DXV A;  1DR5 A;  3F0Q X;  3JSU A;  1S3W A;  1DR6 A;  1DHJ A;  2DRC A;  4NX7 A;  4HA7 A;  3DGA A;  3ZPG A;  1DR1 A;  3F0B X;  1PDB A;  2W3M A;  1RB3 A;  5CC9 A;  4PSS A;  2GD9 A;  2H2Q A;  3FYW X;  3E0B A;  1DRH A;  4IXE D;  3DAU A;  1RX9 A;  3QG2 A;  6DFR A;  3QLR A;  3K45 A;  3TQA A;  1RA3 A;  4DP3 A;  2HM9 A;  3UM5 A;  4M6J A;  1RX6 A;  3F0X X;  3IA4 A;  1TDR A;  3DAT A;  4QJZ D;  3QGT A;  2JYB A;  1M7A A;  1ZDR A;  4ELE A;  4Q0E A;  2QK8 A;  1KMV A;  3SAI A;  5ECX A;  1DR2 A;  5U27 A;  4KD7 A;  3EEM A;  3S3V A;  3S7A A;  1S3U A;  2L28 A;  3EEL A;  4RGC A;  1VDR A;  1RC4 A;  3SQY X;  4KL9 A;  4Q67 A;  4X5G A;  1DRE A;  4M7V A;  3NXY A;  4LAE X;  4CD2 A;  1DRF A;  3IA5 A;  4OSG A;  2HQP A;  4PSY A;  3SRU X;  3KJS A;  4XEC X;  4EJ1 A;  4KAK A;  7DFR A;  4M6L A;  3SRW X;  4KFJ A;  3JW3 A;  3NXR A;  1DDR A;  3CL9 A;  4H95 A;  1DHI A;  3JWC A;  5HT5 A;  3EX8 A;  3F0V X;  4M7U A;  1M79 A;  2W9H A;  4QLE A;  5EAJ A;  2C2T A;  4ECK A;  3SGY A;  4G8Z X;  3FY8 X;  5DFR A;  1MVS A;  1IA2 A;  4ELB A;  1U71 A;  4P3R A;  3NZD A;  3FRA X;  2P4G A;  3FRF X;  1DAJ A;  1LUD A;  3SRQ X;  1RA1 A;  3NZA X;  1DG5 A;  2FZH A;  3FQC A;  1PD8 A;  3L3R A;  3NZB X;  3F91 A;  2B3Z A;  5HUI A;  5HI6 A;  4X5J A;  3NXX A;  4PST A; 
#chains in the Genus database with same CATH topology
 3QLW A;  1RB2 A;  3QL3 A;  5HF0 X;  3QYO A;  1D1G A;  2BLC A;  3QL0 A;  1JOL A;  2G6V A;  4XE6 X;  3R33 A;  2ZZA A;  1PD9 A;  3F8Y A;  4EIL A;  3NZ6 X;  4KNE A;  5HVE A;  3F0S X;  3NZ9 X;  3IRM A;  3QFX A;  4NX6 A;  4TU5 X;  1DIS A;  1SEJ A;  1DRA A;  4DFR A;  2CD2 A;  1LY3 A;  4XT5 A;  2D0K A;  3D80 A;  3OCH A;  4IXF X;  2BL9 A;  1DG7 A;  1CD2 A;  3FQO A;  1RX4 A;  4Q6A A;  4IXG X;  4KY4 A;  1RE7 A;  3ZPC A;  2ITH A;  2BLB A;  1CZ3 A;  4PTJ A;  4XT8 A;  2OBC A;  4QLG A;  4I13 A;  4DPH A;  3M09 A;  1OHK A;  4KBN A;  4OR7 A;  1DYJ A;  2W3W A;  4ELF A;  2W9T A;  1RF7 A;  4LAH X;  3CLB A;  3FY9 X;  3SA1 A;  1QZF A;  1RX8 A;  4G95 A;  3F8Z A;  3KY8 A;  1DRB A;  4PTH A;  4GH8 A;  3FQV A;  3UM6 A;  4H96 A;  3GYF A;  3JWK A;  3TQ9 A;  4HOF A;  3NRR A;  3CD2 A;  3DFR A;  1YHO A;  3SR5 X;  3FYV X;  1IA3 A;  3EEK A;  5HSU A;  2AZN A;  1DYR A;  5E8Q A;  5ECC A;  3FS6 A;  3IRO A;  1HFR A;  3JW5 A;  3KGY A;  3ROA A;  2W3B A;  2KGK A;  4M6K A;  3JWM A;  3QLZ A;  1DIU A;  3DG8 A;  3EEJ A;  3K2H A;  4QI9 A;  8DFR A;  4XT7 A;  4FHB A;  3FL8 A;  3I8A X;  3JTW A;  1DF7 A;  1J3K A;  1RD7 A;  3SRR X;  2LF1 A;  1E26 A;  1RG7 A;  4HOE A;  1S3Y A;  1S3V A;  4LAG X;  5JG0 X;  4H98 A;  2DHF A;  4ELG A;  1DHF A;  3IX9 A;  1BZF A;  4X5H A;  3D84 X;  4XT4 A;  3RO9 A;  3Q1H A;  3QLX A;  1RA8 A;  3EIG A;  1DLS A;  4EIG A;  3SA2 A;  5HPB A;  3GI2 A;  4QLF A;  3TQ8 A;  3JWF A;  5CCC A;  1DYH A;  1LY4 A;  3FRE X;  1DG8 A;  3FQF A;  3F0U X;  3NZC X;  3HJ3 A;  4X5F A;  4XT6 A;  1OHJ A;  4KM0 A;  5HQZ A;  3TQB A;  5HSR A;  2C2S A;  3M08 A;  1RX5 A;  2W9G A;  3LG4 A;  3NXV A;  1RH3 A;  1JUV A;  1RX7 A;  2BLA A;  1AI9 A;  1J3I A;  4ELH A;  4HA9 A;  1AO8 A;  1RX1 A;  3DL5 A;  4G3M A;  1U70 A;  1DR4 A;  2INQ A;  2FZI A;  2W9S A;  1IA1 A;  3JVX A;  2XW7 A;  3NXO A;  4KY8 A;  1DR3 A;  3K74 A;  2ANO A;  5HVB A;  4X5I A;  3GHW A;  5JA3 A;  2ANQ A;  4KJJ A;  1HFQ A;  4EIZ A;  2OIP A;  3NU0 A;  4PDJ A;  3IRN A;  2D5N A;  1HFP A;  4P66 A;  4P3Q A;  1M78 A;  3SRS X;  4FGH A;  3VCO A;  3QLS A;  1RA9 A;  1DDS A;  4H97 A;  1RA2 A;  3HBB A;  2O7P A;  3UM8 A;  4Q0D A;  4KLX A;  3TD8 A;  2W3V A;  4QHV A;  4FGG A;  3CSE A;  3DL6 A;  3INV A;  1IA4 A;  3GHV A;  1RX3 A;  2CIG A;  3RG9 A;  4KM2 A;  3KJR A;  3I3R A;  3N0H A;  4P68 A;  1JOM A;  1BOZ A;  1MVT A;  5HT4 A;  3DRC A;  3FQ0 A;  3NTZ A;  1J3J A;  1RX2 A;  4DDR A;  3FRD X;  3FQZ A;  2HXV A;  5HF2 X;  3K47 A;  4I1N A;  3QLY A;  5U26 A;  3QYL A;  1AOE A;  2FZJ A;  4KJK A;  3KFY A;  1KLK A;  2W3A A;  1VJ3 A;  1DYI A;  4QJC A;  4KYA A;  4KEB A;  1U72 A;  3GHC A;  4KJL A;  4DPD A;  3FL9 A;  1KMS A;  3FRB X;  4HOG A;  1DLR A;  1DR7 A;  3NXT A;  3OAF A;  5FDA A;  5HQY A;  4M2X A;  4XRB A;  3S9U A;  4LEK X;  3SH2 A;  5DXV A;  1DR5 A;  3F0Q X;  3JSU A;  1S3W A;  1DR6 A;  1DHJ A;  2DRC A;  4NX7 A;  4HA7 A;  3DGA A;  3ZPG A;  1DR1 A;  3F0B X;  1PDB A;  2W3M A;  1RB3 A;  5CC9 A;  4PSS A;  2GD9 A;  2H2Q A;  3FYW X;  3E0B A;  1DRH A;  4IXE D;  3DAU A;  1RX9 A;  3QG2 A;  6DFR A;  3QLR A;  3K45 A;  3TQA A;  1RA3 A;  4DP3 A;  2HM9 A;  3UM5 A;  4M6J A;  1RX6 A;  3F0X X;  3IA4 A;  1TDR A;  3DAT A;  4QJZ D;  3QGT A;  2JYB A;  1M7A A;  1ZDR A;  4ELE A;  4Q0E A;  2QK8 A;  1KMV A;  3SAI A;  5ECX A;  1DR2 A;  5U27 A;  4KD7 A;  3EEM A;  3S3V A;  3S7A A;  1S3U A;  2L28 A;  3EEL A;  4RGC A;  1VDR A;  1RC4 A;  3SQY X;  4KL9 A;  4Q67 A;  4X5G A;  1DRE A;  4M7V A;  3NXY A;  4LAE X;  4CD2 A;  1DRF A;  3IA5 A;  4OSG A;  2HQP A;  4PSY A;  3SRU X;  3KJS A;  4XEC X;  4EJ1 A;  4KAK A;  7DFR A;  4M6L A;  3SRW X;  4KFJ A;  3JW3 A;  3NXR A;  1DDR A;  3CL9 A;  4H95 A;  1DHI A;  3JWC A;  5HT5 A;  3EX8 A;  3F0V X;  4M7U A;  1M79 A;  2W9H A;  4QLE A;  5EAJ A;  2C2T A;  4ECK A;  3SGY A;  4G8Z X;  3FY8 X;  5DFR A;  1MVS A;  1IA2 A;  4ELB A;  1U71 A;  4P3R A;  3NZD A;  3FRA X;  2P4G A;  3FRF X;  1DAJ A;  1LUD A;  3SRQ X;  1RA1 A;  3NZA X;  1DG5 A;  2FZH A;  3FQC A;  1PD8 A;  3L3R A;  3NZB X;  3F91 A;  2B3Z A;  5HUI A;  5HI6 A;  4X5J A;  3NXX A;  4PST A; 
#chains in the Genus database with same CATH homology
 3QLW A;  1RB2 A;  3QL3 A;  5HF0 X;  3QYO A;  1D1G A;  2BLC A;  3QL0 A;  1JOL A;  2G6V A;  4XE6 X;  3R33 A;  2ZZA A;  1PD9 A;  3F8Y A;  4EIL A;  3NZ6 X;  4KNE A;  5HVE A;  3F0S X;  3NZ9 X;  3IRM A;  3QFX A;  4NX6 A;  4TU5 X;  1DIS A;  1SEJ A;  1DRA A;  4DFR A;  2CD2 A;  1LY3 A;  4XT5 A;  2D0K A;  3D80 A;  3OCH A;  4IXF X;  2BL9 A;  1DG7 A;  1CD2 A;  3FQO A;  1RX4 A;  4Q6A A;  4IXG X;  4KY4 A;  1RE7 A;  3ZPC A;  2ITH A;  2BLB A;  1CZ3 A;  4PTJ A;  4XT8 A;  2OBC A;  4QLG A;  4I13 A;  4DPH A;  3M09 A;  1OHK A;  4KBN A;  4OR7 A;  1DYJ A;  2W3W A;  4ELF A;  2W9T A;  1RF7 A;  4LAH X;  3CLB A;  3FY9 X;  3SA1 A;  1QZF A;  1RX8 A;  4G95 A;  3F8Z A;  3KY8 A;  1DRB A;  4PTH A;  4GH8 A;  3FQV A;  3UM6 A;  4H96 A;  3GYF A;  3JWK A;  3TQ9 A;  4HOF A;  3NRR A;  3CD2 A;  3DFR A;  1YHO A;  3SR5 X;  3FYV X;  1IA3 A;  3EEK A;  5HSU A;  2AZN A;  1DYR A;  5E8Q A;  5ECC A;  3FS6 A;  3IRO A;  1HFR A;  3JW5 A;  3KGY A;  3ROA A;  2W3B A;  2KGK A;  4M6K A;  3JWM A;  3QLZ A;  1DIU A;  3DG8 A;  3EEJ A;  3K2H A;  4QI9 A;  8DFR A;  4XT7 A;  4FHB A;  3FL8 A;  3I8A X;  3JTW A;  1DF7 A;  1J3K A;  1RD7 A;  3SRR X;  2LF1 A;  1E26 A;  1RG7 A;  4HOE A;  1S3Y A;  1S3V A;  4LAG X;  5JG0 X;  4H98 A;  2DHF A;  4ELG A;  1DHF A;  3IX9 A;  1BZF A;  4X5H A;  3D84 X;  4XT4 A;  3RO9 A;  3Q1H A;  3QLX A;  1RA8 A;  3EIG A;  1DLS A;  4EIG A;  3SA2 A;  5HPB A;  3GI2 A;  4QLF A;  3TQ8 A;  3JWF A;  5CCC A;  1DYH A;  1LY4 A;  3FRE X;  1DG8 A;  3FQF A;  3F0U X;  3NZC X;  3HJ3 A;  4X5F A;  4XT6 A;  1OHJ A;  4KM0 A;  5HQZ A;  3TQB A;  5HSR A;  2C2S A;  3M08 A;  1RX5 A;  2W9G A;  3LG4 A;  3NXV A;  1RH3 A;  1JUV A;  1RX7 A;  2BLA A;  1AI9 A;  1J3I A;  4ELH A;  4HA9 A;  1AO8 A;  1RX1 A;  3DL5 A;  4G3M A;  1U70 A;  1DR4 A;  2INQ A;  2FZI A;  2W9S A;  1IA1 A;  3JVX A;  2XW7 A;  3NXO A;  4KY8 A;  1DR3 A;  3K74 A;  2ANO A;  5HVB A;  4X5I A;  3GHW A;  5JA3 A;  2ANQ A;  4KJJ A;  1HFQ A;  4EIZ A;  2OIP A;  3NU0 A;  4PDJ A;  3IRN A;  2D5N A;  1HFP A;  4P66 A;  4P3Q A;  1M78 A;  3SRS X;  4FGH A;  3VCO A;  3QLS A;  1RA9 A;  1DDS A;  4H97 A;  1RA2 A;  3HBB A;  2O7P A;  3UM8 A;  4Q0D A;  4KLX A;  3TD8 A;  2W3V A;  4QHV A;  4FGG A;  3CSE A;  3DL6 A;  3INV A;  1IA4 A;  3GHV A;  1RX3 A;  2CIG A;  3RG9 A;  4KM2 A;  3KJR A;  3I3R A;  3N0H A;  4P68 A;  1JOM A;  1BOZ A;  1MVT A;  5HT4 A;  3DRC A;  3FQ0 A;  3NTZ A;  1J3J A;  1RX2 A;  4DDR A;  3FRD X;  3FQZ A;  2HXV A;  5HF2 X;  3K47 A;  4I1N A;  3QLY A;  5U26 A;  3QYL A;  1AOE A;  2FZJ A;  4KJK A;  3KFY A;  1KLK A;  2W3A A;  1VJ3 A;  1DYI A;  4QJC A;  4KYA A;  4KEB A;  1U72 A;  3GHC A;  4KJL A;  4DPD A;  3FL9 A;  1KMS A;  3FRB X;  4HOG A;  1DLR A;  1DR7 A;  3NXT A;  3OAF A;  5FDA A;  5HQY A;  4M2X A;  4XRB A;  3S9U A;  4LEK X;  3SH2 A;  5DXV A;  1DR5 A;  3F0Q X;  3JSU A;  1S3W A;  1DR6 A;  1DHJ A;  2DRC A;  4NX7 A;  4HA7 A;  3DGA A;  3ZPG A;  1DR1 A;  3F0B X;  1PDB A;  2W3M A;  1RB3 A;  5CC9 A;  4PSS A;  2GD9 A;  2H2Q A;  3FYW X;  3E0B A;  1DRH A;  4IXE D;  3DAU A;  1RX9 A;  3QG2 A;  6DFR A;  3QLR A;  3K45 A;  3TQA A;  1RA3 A;  4DP3 A;  2HM9 A;  3UM5 A;  4M6J A;  1RX6 A;  3F0X X;  3IA4 A;  1TDR A;  3DAT A;  4QJZ D;  3QGT A;  2JYB A;  1M7A A;  1ZDR A;  4ELE A;  4Q0E A;  2QK8 A;  1KMV A;  3SAI A;  5ECX A;  1DR2 A;  5U27 A;  4KD7 A;  3EEM A;  3S3V A;  3S7A A;  1S3U A;  2L28 A;  3EEL A;  4RGC A;  1VDR A;  1RC4 A;  3SQY X;  4KL9 A;  4Q67 A;  4X5G A;  1DRE A;  4M7V A;  3NXY A;  4LAE X;  4CD2 A;  1DRF A;  3IA5 A;  4OSG A;  2HQP A;  4PSY A;  3SRU X;  3KJS A;  4XEC X;  4EJ1 A;  4KAK A;  7DFR A;  4M6L A;  3SRW X;  4KFJ A;  3JW3 A;  3NXR A;  1DDR A;  3CL9 A;  4H95 A;  1DHI A;  3JWC A;  5HT5 A;  3EX8 A;  3F0V X;  4M7U A;  1M79 A;  2W9H A;  4QLE A;  5EAJ A;  2C2T A;  4ECK A;  3SGY A;  4G8Z X;  3FY8 X;  5DFR A;  1MVS A;  1IA2 A;  4ELB A;  1U71 A;  4P3R A;  3NZD A;  3FRA X;  2P4G A;  3FRF X;  1DAJ A;  1LUD A;  3SRQ X;  1RA1 A;  3NZA X;  1DG5 A;  2FZH A;  3FQC A;  1PD8 A;  3L3R A;  3NZB X;  3F91 A;  2B3Z A;  5HUI A;  5HI6 A;  4X5J A;  3NXX A;  4PST A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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