4XE6X

Staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3r)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl]pyrimidine-2,4-diamine (ucp1061)
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
157
structure length
157
Chain Sequence
TLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Stereo-selectively Induced Cofactor Switching Provides Insight into Cofactor Site Plasticity as a Possible Mechanism of Antifolate Resistance
rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Staphylococcus aureus
molecule keywords Dihydrofolate reductase
total genus 40
structure length 157
sequence length 157
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-12-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4xe6X00
1DLRA 1S3WA 2GD9A 4FGHA 5DFRA 1U72A 4Q0EA 2ITHA 5U27A 3NZDA 3SAIA 3N0HA 3QYOA 4TU5X 1J3JA 1RX5A 4X5GA 2HQPA 2W3VA 3NU0A 4M7VA 3NXOA 1DR1A 3KGYA 4ELGA 3D84X 1CD2A 3D80A 3JWCA 1AO8A 1TDRA 4EIGA 4XT8A 1DYIA 2D0KA 4M2XA 3F0VX 5HF2X 1DR6A 3CL9A 3FQZA 3UM8A 2BL9A 3QYLA 1RC4A 5HQYA 5HVEA 3EIGA 4KJKA 3CD2A 3SR5X 3Q1HA 3SA1A 3SRSX 3DAUA 5HVBA 2ANQA 1AI9A 1ZDRA 4ELEA 4LAHX 3NZAX 3NZBX 3FL9A 1LY4A 3KJSA 1DR2A 5JA3A 1RF7A 1DLSA 3EEKA 3JSUA 1S3VA 2FZIA 3FL8A 3IA5A 4PSTA 1DR7A 1HFRA 1JUVA 3KJRA 3NZ6X 2W9TA 2W9SA 1VDRA 3IA4A 3FYVX 4CD2A 3SRQX 3HJ3A 4PSYA 4G3MA 2QK8A 1RA2A 7DFRA 3FS6A 2O7PA 3SRUX 4ECKA 4H95A 4X5IA 4OSGA 4XT6A 1RX6A 4QJCA 2L28A 3F0SX 1RX8A 4KY8A 1U71A 1J3IA 3VCOA 4KYAA 4LAGX 2ZZAA 3QGTA 4DPHA 3DRCA 1RA9A 3NZ9X 2AZNA 4OR7A 1DISA 1LY3A 2OIPA 4QI9A 3JWMA 3F91A 5HT5A 4XECX 3OAFA 4KY4A 3SQYX 1OHJA 4GH8A 4KJLA 1DAJA 1JOLA 1DHJA 3FYWX 1MVSA 5EAJA 3LG4A 1OHKA 1KMSA 3M08A 4M6JA 3DGAA 3K2HA 3NRRA 4QHVA 3S3VA 3UM6A 5U26A 4P3RA 3GI2A 1DIUA 2DHFA 3NXYA 1E26A 2BLBA 2H2QA 2B3ZA 3JW3A 3DATA 5JG0X 4X5FA 3DG8A 2INQA 1DDSA 1BZFA 3EELA 2HXVA 1IA1A 1RX7A 5ECXA 2G6VA 1PDBA 2W3AA 3IRNA 1RX2A 4KAKA 3TQBA 4M6LA 3SRWX 4G95A 4HOFA 4EIZA 1DRFA 4Q67A 1M7AA 5CC9A 4RGCA 1RX1A 4KJJA 3TD8A 3TQ9A 1DHFA 1DG5A 2FZHA 3TQAA 1DREA 3IRMA 5HT4A 2OBCA 1HFQA 1DRBA 4H97A 4NX6A 2JYBA 3FY8X 1DRAA 3F0UX 2DRCA 5CCCA 3DL5A 3F8ZA 2XW7A 3HBBA 3UM5A 1HFPA 1RA8A 5HSRA 4LEKX 3NXRA 1KMVA 3F0QX 4PTHA 5HF0X 3SGYA 4EJ1A 1U70A 3F0BX 1RX9A 1D1GA 3E0BA 3NXXA 3ROAA 3QL0A 1RB3A 3NZCX 3QG2A 3K47A 4Q0DA 1PD8A 1RE7A 1IA2A 3FQVA 2W3BA 4FHBA 2KGKA 3SH2A 2CIGA 3FRFX 4KM0A 4KLXA 3FQOA 3GHCA 1DYJA 4DFRA 4H98A 3IX9A 4X5HA 4PDJA 1IA3A 4EILA 4PSSA 4ELBA 3QLYA 4XT4A 3FQ0A 4XRBA 4KD7A 4QLGA 4DDRA 4FGGA 5HPBA 3R33A 3SA2A 1SEJA 3EEMA 2BLCA 3F8YA 4LAEX 1DR4A 1DG8A 3L3RA 3CLBA 3S7AA 3DFRA 3OCHA 3QL3A 3ZPCA 2FZJA 3JWKA 4IXFX 4ELFA 1VJ3A 1RB2A 5FDAA 3JVXA 3I3RA 4X5JA 4DP3A 4G8ZX 2W9HA 4HA7A 1RH3A 1DG7A 1RX4A 4QLFA 3M09A 4KM2A 4XE6X 3SRRX 5HQZA 4DPDA 3RG9A 1RD7A 4M7UA 1JOMA 1DDRA 2C2TA 2W3WA 1RA1A 1DF7A 4HOEA 3KY8A 4NX7A 1MVTA 2CD2A 5E8QA 4Q6AA 4QLEA 4KL9A 3JTWA 2C2SA 4I13A 3K45A 3EEJA 5HSUA 3FQFA 4KNEA 1IA4A 5HI6A 4XT7A 3FRBX 3S9UA 3FQCA 1DRHA 1S3UA 1DYHA 4M6KA 5ECCA 3F0XX 3QLSA 4HA9A 1DYRA 3CSEA 1M78A 1KLKA 1RA3A 3QFXA 3NXTA 3GYFA 4HOGA 1BOZA 1DR3A 4P3QA 3QLZA 3INVA 3RO9A 4P68A 3FRAX 3NXVA 1S3YA 3ZPGA 3IROA 4H96A 2HM9A 3JWFA 1CZ3A 5HUIA 4PTJA 2LF1A 3QLRA 1RG7A 2D5NA 1LUDA 1PD9A 1J3KA 3TQ8A 3DL6A 4IXED 3FY9X 2P4GA 6DFRA 1YHOA 2W3MA 4XT5A 1M79A 3EX8A 5DXVA 4KBNA 4KEBA 3GHWA 1DHIA 2BLAA 3QLXA 2W9GA 3GHVA 3QLWA 1DR5A 3FREX 3K74A 4ELHA 1QZFA 3JW5A 2ANOA 4KFJA 4P66A 1AOEA 4IXGX 4QJZD 8DFRA 3I8AX 3KFYA 4I1NA 3NTZA 1RX3A 3FRDX
chains in the Genus database with same CATH superfamily
1DLRA 1S3WA 2GD9A 4FGHA 5DFRA 1U72A 4Q0EA 2ITHA 5U27A 3NZDA 3SAIA 3N0HA 3QYOA 4TU5X 1J3JA 1RX5A 4X5GA 2HQPA 2W3VA 3NU0A 4M7VA 3NXOA 1DR1A 3KGYA 4ELGA 3D84X 1CD2A 3D80A 3JWCA 1AO8A 1TDRA 4EIGA 4XT8A 1DYIA 2D0KA 4M2XA 3F0VX 5HF2X 1DR6A 3CL9A 3FQZA 3UM8A 2BL9A 3QYLA 1RC4A 5HQYA 5HVEA 3EIGA 4KJKA 3CD2A 3SR5X 3Q1HA 3SA1A 3SRSX 3DAUA 5HVBA 2ANQA 1AI9A 1ZDRA 4ELEA 4LAHX 3NZAX 3NZBX 3FL9A 1LY4A 3KJSA 1DR2A 5JA3A 1RF7A 1DLSA 3EEKA 3JSUA 1S3VA 2FZIA 3FL8A 3IA5A 4PSTA 1DR7A 1HFRA 1JUVA 3KJRA 3NZ6X 2W9TA 2W9SA 1VDRA 3IA4A 3FYVX 4CD2A 3SRQX 3HJ3A 4PSYA 4G3MA 2QK8A 1RA2A 7DFRA 3FS6A 2O7PA 3SRUX 4ECKA 4H95A 4X5IA 4OSGA 4XT6A 1RX6A 4QJCA 2L28A 3F0SX 1RX8A 4KY8A 1U71A 1J3IA 3VCOA 4KYAA 4LAGX 2ZZAA 3QGTA 4DPHA 3DRCA 1RA9A 3NZ9X 2AZNA 4OR7A 1DISA 1LY3A 2OIPA 4QI9A 3JWMA 3F91A 5HT5A 4XECX 3OAFA 4KY4A 3SQYX 1OHJA 4GH8A 4KJLA 1DAJA 1JOLA 1DHJA 3FYWX 1MVSA 5EAJA 3LG4A 1OHKA 1KMSA 3M08A 4M6JA 3DGAA 3K2HA 3NRRA 4QHVA 3S3VA 3UM6A 5U26A 4P3RA 3GI2A 1DIUA 2DHFA 3NXYA 1E26A 2BLBA 2H2QA 2B3ZA 3JW3A 3DATA 5JG0X 4X5FA 3DG8A 2INQA 1DDSA 1BZFA 3EELA 2HXVA 1IA1A 1RX7A 5ECXA 2G6VA 1PDBA 2W3AA 3IRNA 1RX2A 4KAKA 3TQBA 4M6LA 3SRWX 4G95A 4HOFA 4EIZA 1DRFA 4Q67A 1M7AA 5CC9A 4RGCA 1RX1A 4KJJA 3TD8A 3TQ9A 1DHFA 1DG5A 2FZHA 3TQAA 1DREA 3IRMA 5HT4A 2OBCA 1HFQA 1DRBA 4H97A 4NX6A 2JYBA 3FY8X 1DRAA 3F0UX 2DRCA 5CCCA 3DL5A 3F8ZA 2XW7A 3HBBA 3UM5A 1HFPA 1RA8A 5HSRA 4LEKX 3NXRA 1KMVA 3F0QX 4PTHA 5HF0X 3SGYA 4EJ1A 1U70A 3F0BX 1RX9A 1D1GA 3E0BA 3NXXA 3ROAA 3QL0A 1RB3A 3NZCX 3QG2A 3K47A 4Q0DA 1PD8A 1RE7A 1IA2A 3FQVA 2W3BA 4FHBA 2KGKA 3SH2A 2CIGA 3FRFX 4KM0A 4KLXA 3FQOA 3GHCA 1DYJA 4DFRA 4H98A 3IX9A 4X5HA 4PDJA 1IA3A 4EILA 4PSSA 4ELBA 3QLYA 4XT4A 3FQ0A 4XRBA 4KD7A 4QLGA 4DDRA 4FGGA 5HPBA 3R33A 3SA2A 1SEJA 3EEMA 2BLCA 3F8YA 4LAEX 1DR4A 1DG8A 3L3RA 3CLBA 3S7AA 3DFRA 3OCHA 3QL3A 3ZPCA 2FZJA 3JWKA 4IXFX 4ELFA 1VJ3A 1RB2A 5FDAA 3JVXA 3I3RA 4X5JA 4DP3A 4G8ZX 2W9HA 4HA7A 1RH3A 1DG7A 1RX4A 4QLFA 3M09A 4KM2A 4XE6X 3SRRX 5HQZA 4DPDA 3RG9A 1RD7A 4M7UA 1JOMA 1DDRA 2C2TA 2W3WA 1RA1A 1DF7A 4HOEA 3KY8A 4NX7A 1MVTA 2CD2A 5E8QA 4Q6AA 4QLEA 4KL9A 3JTWA 2C2SA 4I13A 3K45A 3EEJA 5HSUA 3FQFA 4KNEA 1IA4A 5HI6A 4XT7A 3FRBX 3S9UA 3FQCA 1DRHA 1S3UA 1DYHA 4M6KA 5ECCA 3F0XX 3QLSA 4HA9A 1DYRA 3CSEA 1M78A 1KLKA 1RA3A 3QFXA 3NXTA 3GYFA 4HOGA 1BOZA 1DR3A 4P3QA 3QLZA 3INVA 3RO9A 4P68A 3FRAX 3NXVA 1S3YA 3ZPGA 3IROA 4H96A 2HM9A 3JWFA 1CZ3A 5HUIA 4PTJA 2LF1A 3QLRA 1RG7A 2D5NA 1LUDA 1PD9A 1J3KA 3TQ8A 3DL6A 4IXED 3FY9X 2P4GA 6DFRA 1YHOA 2W3MA 4XT5A 1M79A 3EX8A 5DXVA 4KBNA 4KEBA 3GHWA 1DHIA 2BLAA 3QLXA 2W9GA 3GHVA 3QLWA 1DR5A 3FREX 3K74A 4ELHA 1QZFA 3JW5A 2ANOA 4KFJA 4P66A 1AOEA 4IXGX 4QJZD 8DFRA 3I8AX 3KFYA 4I1NA 3NTZA 1RX3A 3FRDX
chains in the Genus database with same CATH topology
1DLRA 1S3WA 2GD9A 4FGHA 5DFRA 1U72A 4Q0EA 2ITHA 5U27A 3NZDA 3SAIA 3N0HA 3QYOA 4TU5X 1J3JA 1RX5A 4X5GA 2HQPA 2W3VA 3NU0A 4M7VA 3NXOA 1DR1A 3KGYA 4ELGA 3D84X 1CD2A 3D80A 3JWCA 1AO8A 1TDRA 4EIGA 4XT8A 1DYIA 2D0KA 4M2XA 3F0VX 5HF2X 1DR6A 3CL9A 3FQZA 3UM8A 2BL9A 3QYLA 1RC4A 5HQYA 5HVEA 3EIGA 4KJKA 3CD2A 3SR5X 3Q1HA 3SA1A 3SRSX 3DAUA 5HVBA 2ANQA 1AI9A 1ZDRA 4ELEA 4LAHX 3NZAX 3NZBX 3FL9A 1LY4A 3KJSA 1DR2A 5JA3A 1RF7A 1DLSA 3EEKA 3JSUA 1S3VA 2FZIA 3FL8A 3IA5A 4PSTA 1DR7A 1HFRA 1JUVA 3KJRA 3NZ6X 2W9TA 2W9SA 1VDRA 3IA4A 3FYVX 4CD2A 3SRQX 3HJ3A 4PSYA 4G3MA 2QK8A 1RA2A 7DFRA 3FS6A 2O7PA 3SRUX 4ECKA 4H95A 4X5IA 4OSGA 4XT6A 1RX6A 4QJCA 2L28A 3F0SX 1RX8A 4KY8A 1U71A 1J3IA 3VCOA 4KYAA 4LAGX 2ZZAA 3QGTA 4DPHA 3DRCA 1RA9A 3NZ9X 2AZNA 4OR7A 1DISA 1LY3A 2OIPA 4QI9A 3JWMA 3F91A 5HT5A 4XECX 3OAFA 4KY4A 3SQYX 1OHJA 4GH8A 4KJLA 1DAJA 1JOLA 1DHJA 3FYWX 1MVSA 5EAJA 3LG4A 1OHKA 1KMSA 3M08A 4M6JA 3DGAA 3K2HA 3NRRA 4QHVA 3S3VA 3UM6A 5U26A 4P3RA 3GI2A 1DIUA 2DHFA 3NXYA 1E26A 2BLBA 2H2QA 2B3ZA 3JW3A 3DATA 5JG0X 4X5FA 3DG8A 2INQA 1DDSA 1BZFA 3EELA 2HXVA 1IA1A 1RX7A 5ECXA 2G6VA 1PDBA 2W3AA 3IRNA 1RX2A 4KAKA 3TQBA 4M6LA 3SRWX 4G95A 4HOFA 4EIZA 1DRFA 4Q67A 1M7AA 5CC9A 4RGCA 1RX1A 4KJJA 3TD8A 3TQ9A 1DHFA 1DG5A 2FZHA 3TQAA 1DREA 3IRMA 5HT4A 2OBCA 1HFQA 1DRBA 4H97A 4NX6A 2JYBA 3FY8X 1DRAA 3F0UX 2DRCA 5CCCA 3DL5A 3F8ZA 2XW7A 3HBBA 3UM5A 1HFPA 1RA8A 5HSRA 4LEKX 3NXRA 1KMVA 3F0QX 4PTHA 5HF0X 3SGYA 4EJ1A 1U70A 3F0BX 1RX9A 1D1GA 3E0BA 3NXXA 3ROAA 3QL0A 1RB3A 3NZCX 3QG2A 3K47A 4Q0DA 1PD8A 1RE7A 1IA2A 3FQVA 2W3BA 4FHBA 2KGKA 3SH2A 2CIGA 3FRFX 4KM0A 4KLXA 3FQOA 3GHCA 1DYJA 4DFRA 4H98A 3IX9A 4X5HA 4PDJA 1IA3A 4EILA 4PSSA 4ELBA 3QLYA 4XT4A 3FQ0A 4XRBA 4KD7A 4QLGA 4DDRA 4FGGA 5HPBA 3R33A 3SA2A 1SEJA 3EEMA 2BLCA 3F8YA 4LAEX 1DR4A 1DG8A 3L3RA 3CLBA 3S7AA 3DFRA 3OCHA 3QL3A 3ZPCA 2FZJA 3JWKA 4IXFX 4ELFA 1VJ3A 1RB2A 5FDAA 3JVXA 3I3RA 4X5JA 4DP3A 4G8ZX 2W9HA 4HA7A 1RH3A 1DG7A 1RX4A 4QLFA 3M09A 4KM2A 4XE6X 3SRRX 5HQZA 4DPDA 3RG9A 1RD7A 4M7UA 1JOMA 1DDRA 2C2TA 2W3WA 1RA1A 1DF7A 4HOEA 3KY8A 4NX7A 1MVTA 2CD2A 5E8QA 4Q6AA 4QLEA 4KL9A 3JTWA 2C2SA 4I13A 3K45A 3EEJA 5HSUA 3FQFA 4KNEA 1IA4A 5HI6A 4XT7A 3FRBX 3S9UA 3FQCA 1DRHA 1S3UA 1DYHA 4M6KA 5ECCA 3F0XX 3QLSA 4HA9A 1DYRA 3CSEA 1M78A 1KLKA 1RA3A 3QFXA 3NXTA 3GYFA 4HOGA 1BOZA 1DR3A 4P3QA 3QLZA 3INVA 3RO9A 4P68A 3FRAX 3NXVA 1S3YA 3ZPGA 3IROA 4H96A 2HM9A 3JWFA 1CZ3A 5HUIA 4PTJA 2LF1A 3QLRA 1RG7A 2D5NA 1LUDA 1PD9A 1J3KA 3TQ8A 3DL6A 4IXED 3FY9X 2P4GA 6DFRA 1YHOA 2W3MA 4XT5A 1M79A 3EX8A 5DXVA 4KBNA 4KEBA 3GHWA 1DHIA 2BLAA 3QLXA 2W9GA 3GHVA 3QLWA 1DR5A 3FREX 3K74A 4ELHA 1QZFA 3JW5A 2ANOA 4KFJA 4P66A 1AOEA 4IXGX 4QJZD 8DFRA 3I8AX 3KFYA 4I1NA 3NTZA 1RX3A 3FRDX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DLR A;  1S3W A;  2GD9 A;  4FGH A;  5DFR A;  1U72 A;  4Q0E A;  2ITH A;  5U27 A;  3NZD A;  3SAI A;  3N0H A;  3QYO A;  4TU5 X;  1J3J A;  1RX5 A;  4X5G A;  2HQP A;  2W3V A;  3NU0 A;  4M7V A;  3NXO A;  1DR1 A;  3KGY A;  4ELG A;  3D84 X;  1CD2 A;  3D80 A;  3JWC A;  1AO8 A;  1TDR A;  4EIG A;  4XT8 A;  1DYI A;  2D0K A;  4M2X A;  3F0V X;  5HF2 X;  1DR6 A;  3CL9 A;  3FQZ A;  3UM8 A;  2BL9 A;  3QYL A;  1RC4 A;  5HQY A;  5HVE A;  3EIG A;  4KJK A;  3CD2 A;  3SR5 X;  3Q1H A;  3SA1 A;  3SRS X;  3DAU A;  5HVB A;  2ANQ A;  1AI9 A;  1ZDR A;  4ELE A;  4LAH X;  3NZA X;  3NZB X;  3FL9 A;  1LY4 A;  3KJS A;  1DR2 A;  5JA3 A;  1RF7 A;  1DLS A;  3EEK A;  3JSU A;  1S3V A;  2FZI A;  3FL8 A;  3IA5 A;  4PST A;  1DR7 A;  1HFR A;  1JUV A;  3KJR A;  3NZ6 X;  2W9T A;  2W9S A;  1VDR A;  3IA4 A;  3FYV X;  4CD2 A;  3SRQ X;  3HJ3 A;  4PSY A;  4G3M A;  2QK8 A;  1RA2 A;  7DFR A;  3FS6 A;  2O7P A;  3SRU X;  4ECK A;  4H95 A;  4X5I A;  4OSG A;  4XT6 A;  1RX6 A;  4QJC A;  2L28 A;  3F0S X;  1RX8 A;  4KY8 A;  1U71 A;  1J3I A;  3VCO A;  4KYA A;  4LAG X;  2ZZA A;  3QGT A;  4DPH A;  3DRC A;  1RA9 A;  3NZ9 X;  2AZN A;  4OR7 A;  1DIS A;  1LY3 A;  2OIP A;  4QI9 A;  3JWM A;  3F91 A;  5HT5 A;  4XEC X;  3OAF A;  4KY4 A;  3SQY X;  1OHJ A;  4GH8 A;  4KJL A;  1DAJ A;  1JOL A;  1DHJ A;  3FYW X;  1MVS A;  5EAJ A;  3LG4 A;  1OHK A;  1KMS A;  3M08 A;  4M6J A;  3DGA A;  3K2H A;  3NRR A;  4QHV A;  3S3V A;  3UM6 A;  5U26 A;  4P3R A;  3GI2 A;  1DIU A;  2DHF A;  3NXY A;  1E26 A;  2BLB A;  2H2Q A;  2B3Z A;  3JW3 A;  3DAT A;  5JG0 X;  4X5F A;  3DG8 A;  2INQ A;  1DDS A;  1BZF A;  3EEL A;  2HXV A;  1IA1 A;  1RX7 A;  5ECX A;  2G6V A;  1PDB A;  2W3A A;  3IRN A;  1RX2 A;  4KAK A;  3TQB A;  4M6L A;  3SRW X;  4G95 A;  4HOF A;  4EIZ A;  1DRF A;  4Q67 A;  1M7A A;  5CC9 A;  4RGC A;  1RX1 A;  4KJJ A;  3TD8 A;  3TQ9 A;  1DHF A;  1DG5 A;  2FZH A;  3TQA A;  1DRE A;  3IRM A;  5HT4 A;  2OBC A;  1HFQ A;  1DRB A;  4H97 A;  4NX6 A;  2JYB A;  3FY8 X;  1DRA A;  3F0U X;  2DRC A;  5CCC A;  3DL5 A;  3F8Z A;  2XW7 A;  3HBB A;  3UM5 A;  1HFP A;  1RA8 A;  5HSR A;  4LEK X;  3NXR A;  1KMV A;  3F0Q X;  4PTH A;  5HF0 X;  3SGY A;  4EJ1 A;  1U70 A;  3F0B X;  1RX9 A;  1D1G A;  3E0B A;  3NXX A;  3ROA A;  3QL0 A;  1RB3 A;  3NZC X;  3QG2 A;  3K47 A;  4Q0D A;  1PD8 A;  1RE7 A;  1IA2 A;  3FQV A;  2W3B A;  4FHB A;  2KGK A;  3SH2 A;  2CIG A;  3FRF X;  4KM0 A;  4KLX A;  3FQO A;  3GHC A;  1DYJ A;  4DFR A;  4H98 A;  3IX9 A;  4X5H A;  4PDJ A;  1IA3 A;  4EIL A;  4PSS A;  4ELB A;  3QLY A;  4XT4 A;  3FQ0 A;  4XRB A;  4KD7 A;  4QLG A;  4DDR A;  4FGG A;  5HPB A;  3R33 A;  3SA2 A;  1SEJ A;  3EEM A;  2BLC A;  3F8Y A;  4LAE X;  1DR4 A;  1DG8 A;  3L3R A;  3CLB A;  3S7A A;  3DFR A;  3OCH A;  3QL3 A;  3ZPC A;  2FZJ A;  3JWK A;  4IXF X;  4ELF A;  1VJ3 A;  1RB2 A;  5FDA A;  3JVX A;  3I3R A;  4X5J A;  4DP3 A;  4G8Z X;  2W9H A;  4HA7 A;  1RH3 A;  1DG7 A;  1RX4 A;  4QLF A;  3M09 A;  4KM2 A;  4XE6 X;  3SRR X;  5HQZ A;  4DPD A;  3RG9 A;  1RD7 A;  4M7U A;  1JOM A;  1DDR A;  2C2T A;  2W3W A;  1RA1 A;  1DF7 A;  4HOE A;  3KY8 A;  4NX7 A;  1MVT A;  2CD2 A;  5E8Q A;  4Q6A A;  4QLE A;  4KL9 A;  3JTW A;  2C2S A;  4I13 A;  3K45 A;  3EEJ A;  5HSU A;  3FQF A;  4KNE A;  1IA4 A;  5HI6 A;  4XT7 A;  3FRB X;  3S9U A;  3FQC A;  1DRH A;  1S3U A;  1DYH A;  4M6K A;  5ECC A;  3F0X X;  3QLS A;  4HA9 A;  1DYR A;  3CSE A;  1M78 A;  1KLK A;  1RA3 A;  3QFX A;  3NXT A;  3GYF A;  4HOG A;  1BOZ A;  1DR3 A;  4P3Q A;  3QLZ A;  3INV A;  3RO9 A;  4P68 A;  3FRA X;  3NXV A;  1S3Y A;  3ZPG A;  3IRO A;  4H96 A;  2HM9 A;  3JWF A;  1CZ3 A;  5HUI A;  4PTJ A;  2LF1 A;  3QLR A;  1RG7 A;  2D5N A;  1LUD A;  1PD9 A;  1J3K A;  3TQ8 A;  3DL6 A;  4IXE D;  3FY9 X;  2P4G A;  6DFR A;  1YHO A;  2W3M A;  4XT5 A;  1M79 A;  3EX8 A;  5DXV A;  4KBN A;  4KEB A;  3GHW A;  1DHI A;  2BLA A;  3QLX A;  2W9G A;  3GHV A;  3QLW A;  1DR5 A;  3FRE X;  3K74 A;  4ELH A;  1QZF A;  3JW5 A;  2ANO A;  4KFJ A;  4P66 A;  1AOE A;  4IXG X;  4QJZ D;  8DFR A;  3I8A X;  3KFY A;  4I1N A;  3NTZ A;  1RX3 A;  3FRD X; 
#chains in the Genus database with same CATH topology
 1DLR A;  1S3W A;  2GD9 A;  4FGH A;  5DFR A;  1U72 A;  4Q0E A;  2ITH A;  5U27 A;  3NZD A;  3SAI A;  3N0H A;  3QYO A;  4TU5 X;  1J3J A;  1RX5 A;  4X5G A;  2HQP A;  2W3V A;  3NU0 A;  4M7V A;  3NXO A;  1DR1 A;  3KGY A;  4ELG A;  3D84 X;  1CD2 A;  3D80 A;  3JWC A;  1AO8 A;  1TDR A;  4EIG A;  4XT8 A;  1DYI A;  2D0K A;  4M2X A;  3F0V X;  5HF2 X;  1DR6 A;  3CL9 A;  3FQZ A;  3UM8 A;  2BL9 A;  3QYL A;  1RC4 A;  5HQY A;  5HVE A;  3EIG A;  4KJK A;  3CD2 A;  3SR5 X;  3Q1H A;  3SA1 A;  3SRS X;  3DAU A;  5HVB A;  2ANQ A;  1AI9 A;  1ZDR A;  4ELE A;  4LAH X;  3NZA X;  3NZB X;  3FL9 A;  1LY4 A;  3KJS A;  1DR2 A;  5JA3 A;  1RF7 A;  1DLS A;  3EEK A;  3JSU A;  1S3V A;  2FZI A;  3FL8 A;  3IA5 A;  4PST A;  1DR7 A;  1HFR A;  1JUV A;  3KJR A;  3NZ6 X;  2W9T A;  2W9S A;  1VDR A;  3IA4 A;  3FYV X;  4CD2 A;  3SRQ X;  3HJ3 A;  4PSY A;  4G3M A;  2QK8 A;  1RA2 A;  7DFR A;  3FS6 A;  2O7P A;  3SRU X;  4ECK A;  4H95 A;  4X5I A;  4OSG A;  4XT6 A;  1RX6 A;  4QJC A;  2L28 A;  3F0S X;  1RX8 A;  4KY8 A;  1U71 A;  1J3I A;  3VCO A;  4KYA A;  4LAG X;  2ZZA A;  3QGT A;  4DPH A;  3DRC A;  1RA9 A;  3NZ9 X;  2AZN A;  4OR7 A;  1DIS A;  1LY3 A;  2OIP A;  4QI9 A;  3JWM A;  3F91 A;  5HT5 A;  4XEC X;  3OAF A;  4KY4 A;  3SQY X;  1OHJ A;  4GH8 A;  4KJL A;  1DAJ A;  1JOL A;  1DHJ A;  3FYW X;  1MVS A;  5EAJ A;  3LG4 A;  1OHK A;  1KMS A;  3M08 A;  4M6J A;  3DGA A;  3K2H A;  3NRR A;  4QHV A;  3S3V A;  3UM6 A;  5U26 A;  4P3R A;  3GI2 A;  1DIU A;  2DHF A;  3NXY A;  1E26 A;  2BLB A;  2H2Q A;  2B3Z A;  3JW3 A;  3DAT A;  5JG0 X;  4X5F A;  3DG8 A;  2INQ A;  1DDS A;  1BZF A;  3EEL A;  2HXV A;  1IA1 A;  1RX7 A;  5ECX A;  2G6V A;  1PDB A;  2W3A A;  3IRN A;  1RX2 A;  4KAK A;  3TQB A;  4M6L A;  3SRW X;  4G95 A;  4HOF A;  4EIZ A;  1DRF A;  4Q67 A;  1M7A A;  5CC9 A;  4RGC A;  1RX1 A;  4KJJ A;  3TD8 A;  3TQ9 A;  1DHF A;  1DG5 A;  2FZH A;  3TQA A;  1DRE A;  3IRM A;  5HT4 A;  2OBC A;  1HFQ A;  1DRB A;  4H97 A;  4NX6 A;  2JYB A;  3FY8 X;  1DRA A;  3F0U X;  2DRC A;  5CCC A;  3DL5 A;  3F8Z A;  2XW7 A;  3HBB A;  3UM5 A;  1HFP A;  1RA8 A;  5HSR A;  4LEK X;  3NXR A;  1KMV A;  3F0Q X;  4PTH A;  5HF0 X;  3SGY A;  4EJ1 A;  1U70 A;  3F0B X;  1RX9 A;  1D1G A;  3E0B A;  3NXX A;  3ROA A;  3QL0 A;  1RB3 A;  3NZC X;  3QG2 A;  3K47 A;  4Q0D A;  1PD8 A;  1RE7 A;  1IA2 A;  3FQV A;  2W3B A;  4FHB A;  2KGK A;  3SH2 A;  2CIG A;  3FRF X;  4KM0 A;  4KLX A;  3FQO A;  3GHC A;  1DYJ A;  4DFR A;  4H98 A;  3IX9 A;  4X5H A;  4PDJ A;  1IA3 A;  4EIL A;  4PSS A;  4ELB A;  3QLY A;  4XT4 A;  3FQ0 A;  4XRB A;  4KD7 A;  4QLG A;  4DDR A;  4FGG A;  5HPB A;  3R33 A;  3SA2 A;  1SEJ A;  3EEM A;  2BLC A;  3F8Y A;  4LAE X;  1DR4 A;  1DG8 A;  3L3R A;  3CLB A;  3S7A A;  3DFR A;  3OCH A;  3QL3 A;  3ZPC A;  2FZJ A;  3JWK A;  4IXF X;  4ELF A;  1VJ3 A;  1RB2 A;  5FDA A;  3JVX A;  3I3R A;  4X5J A;  4DP3 A;  4G8Z X;  2W9H A;  4HA7 A;  1RH3 A;  1DG7 A;  1RX4 A;  4QLF A;  3M09 A;  4KM2 A;  4XE6 X;  3SRR X;  5HQZ A;  4DPD A;  3RG9 A;  1RD7 A;  4M7U A;  1JOM A;  1DDR A;  2C2T A;  2W3W A;  1RA1 A;  1DF7 A;  4HOE A;  3KY8 A;  4NX7 A;  1MVT A;  2CD2 A;  5E8Q A;  4Q6A A;  4QLE A;  4KL9 A;  3JTW A;  2C2S A;  4I13 A;  3K45 A;  3EEJ A;  5HSU A;  3FQF A;  4KNE A;  1IA4 A;  5HI6 A;  4XT7 A;  3FRB X;  3S9U A;  3FQC A;  1DRH A;  1S3U A;  1DYH A;  4M6K A;  5ECC A;  3F0X X;  3QLS A;  4HA9 A;  1DYR A;  3CSE A;  1M78 A;  1KLK A;  1RA3 A;  3QFX A;  3NXT A;  3GYF A;  4HOG A;  1BOZ A;  1DR3 A;  4P3Q A;  3QLZ A;  3INV A;  3RO9 A;  4P68 A;  3FRA X;  3NXV A;  1S3Y A;  3ZPG A;  3IRO A;  4H96 A;  2HM9 A;  3JWF A;  1CZ3 A;  5HUI A;  4PTJ A;  2LF1 A;  3QLR A;  1RG7 A;  2D5N A;  1LUD A;  1PD9 A;  1J3K A;  3TQ8 A;  3DL6 A;  4IXE D;  3FY9 X;  2P4G A;  6DFR A;  1YHO A;  2W3M A;  4XT5 A;  1M79 A;  3EX8 A;  5DXV A;  4KBN A;  4KEB A;  3GHW A;  1DHI A;  2BLA A;  3QLX A;  2W9G A;  3GHV A;  3QLW A;  1DR5 A;  3FRE X;  3K74 A;  4ELH A;  1QZF A;  3JW5 A;  2ANO A;  4KFJ A;  4P66 A;  1AOE A;  4IXG X;  4QJZ D;  8DFR A;  3I8A X;  3KFY A;  4I1N A;  3NTZ A;  1RX3 A;  3FRD X; 
#chains in the Genus database with same CATH homology
 1DLR A;  1S3W A;  2GD9 A;  4FGH A;  5DFR A;  1U72 A;  4Q0E A;  2ITH A;  5U27 A;  3NZD A;  3SAI A;  3N0H A;  3QYO A;  4TU5 X;  1J3J A;  1RX5 A;  4X5G A;  2HQP A;  2W3V A;  3NU0 A;  4M7V A;  3NXO A;  1DR1 A;  3KGY A;  4ELG A;  3D84 X;  1CD2 A;  3D80 A;  3JWC A;  1AO8 A;  1TDR A;  4EIG A;  4XT8 A;  1DYI A;  2D0K A;  4M2X A;  3F0V X;  5HF2 X;  1DR6 A;  3CL9 A;  3FQZ A;  3UM8 A;  2BL9 A;  3QYL A;  1RC4 A;  5HQY A;  5HVE A;  3EIG A;  4KJK A;  3CD2 A;  3SR5 X;  3Q1H A;  3SA1 A;  3SRS X;  3DAU A;  5HVB A;  2ANQ A;  1AI9 A;  1ZDR A;  4ELE A;  4LAH X;  3NZA X;  3NZB X;  3FL9 A;  1LY4 A;  3KJS A;  1DR2 A;  5JA3 A;  1RF7 A;  1DLS A;  3EEK A;  3JSU A;  1S3V A;  2FZI A;  3FL8 A;  3IA5 A;  4PST A;  1DR7 A;  1HFR A;  1JUV A;  3KJR A;  3NZ6 X;  2W9T A;  2W9S A;  1VDR A;  3IA4 A;  3FYV X;  4CD2 A;  3SRQ X;  3HJ3 A;  4PSY A;  4G3M A;  2QK8 A;  1RA2 A;  7DFR A;  3FS6 A;  2O7P A;  3SRU X;  4ECK A;  4H95 A;  4X5I A;  4OSG A;  4XT6 A;  1RX6 A;  4QJC A;  2L28 A;  3F0S X;  1RX8 A;  4KY8 A;  1U71 A;  1J3I A;  3VCO A;  4KYA A;  4LAG X;  2ZZA A;  3QGT A;  4DPH A;  3DRC A;  1RA9 A;  3NZ9 X;  2AZN A;  4OR7 A;  1DIS A;  1LY3 A;  2OIP A;  4QI9 A;  3JWM A;  3F91 A;  5HT5 A;  4XEC X;  3OAF A;  4KY4 A;  3SQY X;  1OHJ A;  4GH8 A;  4KJL A;  1DAJ A;  1JOL A;  1DHJ A;  3FYW X;  1MVS A;  5EAJ A;  3LG4 A;  1OHK A;  1KMS A;  3M08 A;  4M6J A;  3DGA A;  3K2H A;  3NRR A;  4QHV A;  3S3V A;  3UM6 A;  5U26 A;  4P3R A;  3GI2 A;  1DIU A;  2DHF A;  3NXY A;  1E26 A;  2BLB A;  2H2Q A;  2B3Z A;  3JW3 A;  3DAT A;  5JG0 X;  4X5F A;  3DG8 A;  2INQ A;  1DDS A;  1BZF A;  3EEL A;  2HXV A;  1IA1 A;  1RX7 A;  5ECX A;  2G6V A;  1PDB A;  2W3A A;  3IRN A;  1RX2 A;  4KAK A;  3TQB A;  4M6L A;  3SRW X;  4G95 A;  4HOF A;  4EIZ A;  1DRF A;  4Q67 A;  1M7A A;  5CC9 A;  4RGC A;  1RX1 A;  4KJJ A;  3TD8 A;  3TQ9 A;  1DHF A;  1DG5 A;  2FZH A;  3TQA A;  1DRE A;  3IRM A;  5HT4 A;  2OBC A;  1HFQ A;  1DRB A;  4H97 A;  4NX6 A;  2JYB A;  3FY8 X;  1DRA A;  3F0U X;  2DRC A;  5CCC A;  3DL5 A;  3F8Z A;  2XW7 A;  3HBB A;  3UM5 A;  1HFP A;  1RA8 A;  5HSR A;  4LEK X;  3NXR A;  1KMV A;  3F0Q X;  4PTH A;  5HF0 X;  3SGY A;  4EJ1 A;  1U70 A;  3F0B X;  1RX9 A;  1D1G A;  3E0B A;  3NXX A;  3ROA A;  3QL0 A;  1RB3 A;  3NZC X;  3QG2 A;  3K47 A;  4Q0D A;  1PD8 A;  1RE7 A;  1IA2 A;  3FQV A;  2W3B A;  4FHB A;  2KGK A;  3SH2 A;  2CIG A;  3FRF X;  4KM0 A;  4KLX A;  3FQO A;  3GHC A;  1DYJ A;  4DFR A;  4H98 A;  3IX9 A;  4X5H A;  4PDJ A;  1IA3 A;  4EIL A;  4PSS A;  4ELB A;  3QLY A;  4XT4 A;  3FQ0 A;  4XRB A;  4KD7 A;  4QLG A;  4DDR A;  4FGG A;  5HPB A;  3R33 A;  3SA2 A;  1SEJ A;  3EEM A;  2BLC A;  3F8Y A;  4LAE X;  1DR4 A;  1DG8 A;  3L3R A;  3CLB A;  3S7A A;  3DFR A;  3OCH A;  3QL3 A;  3ZPC A;  2FZJ A;  3JWK A;  4IXF X;  4ELF A;  1VJ3 A;  1RB2 A;  5FDA A;  3JVX A;  3I3R A;  4X5J A;  4DP3 A;  4G8Z X;  2W9H A;  4HA7 A;  1RH3 A;  1DG7 A;  1RX4 A;  4QLF A;  3M09 A;  4KM2 A;  4XE6 X;  3SRR X;  5HQZ A;  4DPD A;  3RG9 A;  1RD7 A;  4M7U A;  1JOM A;  1DDR A;  2C2T A;  2W3W A;  1RA1 A;  1DF7 A;  4HOE A;  3KY8 A;  4NX7 A;  1MVT A;  2CD2 A;  5E8Q A;  4Q6A A;  4QLE A;  4KL9 A;  3JTW A;  2C2S A;  4I13 A;  3K45 A;  3EEJ A;  5HSU A;  3FQF A;  4KNE A;  1IA4 A;  5HI6 A;  4XT7 A;  3FRB X;  3S9U A;  3FQC A;  1DRH A;  1S3U A;  1DYH A;  4M6K A;  5ECC A;  3F0X X;  3QLS A;  4HA9 A;  1DYR A;  3CSE A;  1M78 A;  1KLK A;  1RA3 A;  3QFX A;  3NXT A;  3GYF A;  4HOG A;  1BOZ A;  1DR3 A;  4P3Q A;  3QLZ A;  3INV A;  3RO9 A;  4P68 A;  3FRA X;  3NXV A;  1S3Y A;  3ZPG A;  3IRO A;  4H96 A;  2HM9 A;  3JWF A;  1CZ3 A;  5HUI A;  4PTJ A;  2LF1 A;  3QLR A;  1RG7 A;  2D5N A;  1LUD A;  1PD9 A;  1J3K A;  3TQ8 A;  3DL6 A;  4IXE D;  3FY9 X;  2P4G A;  6DFR A;  1YHO A;  2W3M A;  4XT5 A;  1M79 A;  3EX8 A;  5DXV A;  4KBN A;  4KEB A;  3GHW A;  1DHI A;  2BLA A;  3QLX A;  2W9G A;  3GHV A;  3QLW A;  1DR5 A;  3FRE X;  3K74 A;  4ELH A;  1QZF A;  3JW5 A;  2ANO A;  4KFJ A;  4P66 A;  1AOE A;  4IXG X;  4QJZ D;  8DFR A;  3I8A X;  3KFY A;  4I1N A;  3NTZ A;  1RX3 A;  3FRD X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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