5HT4A

6-substituted pyrrolo[2,3-d]pyrimidine 6-thieno-(4-methoxyphenyl)
Total Genus 52
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
186
structure length
186
Chain Sequence
VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Homo sapiens
publication title Human dihydrofolate reductase ternary complex with a series of fluorine substituted 5-methyl-6-(4'-methoxyphenythio)[2,3-d]pyrrolo-7-ethyl-2,4-diamines
rcsb
molecule keywords Dihydrofolate reductase
total genus 52
structure length 186
sequence length 186
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2016-01-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 5ht4A00
1DREA 3SR5X 1DHJA 3FRAX 4P3QA 2W3MA 1DR3A 1DHIA 1RG7A 3SRSX 3QGTA 1E26A 1DYRA 3FQ0A 4KJLA 3IRMA 4X5GA 1RX6A 1JUVA 4H95A 1RH3A 4LEKX 1RX8A 4IXED 4M7VA 1DR1A 3E0BA 3NZ9X 1DISA 2DHFA 4X5IA 4QJCA 1DR5A 3F0UX 1JOLA 1DRFA 1M78A 5HF2X 3ROAA 3EEKA 3SQYX 2B3ZA 5HUIA 1VJ3A 2BLAA 1DR6A 3GYFA 4PTJA 1U70A 4HOGA 2W9SA 4H96A 4M7UA 4IXGX 3DL6A 4H98A 2FZIA 3FRBX 2G6VA 4Q67A 4KY4A 3FL8A 1IA2A 1S3VA 5HT5A 3NXOA 3UM8A 1DG7A 2CD2A 3CD2A 3KFYA 1DLSA 5HSUA 3FQFA 4LAGX 4EIGA 1M7AA 3NXXA 3SAIA 3NRRA 4G8ZX 3FQCA 3F0SX 5U27A 3RO9A 1QZFA 3F0XX 2HXVA 4PSSA 4ELGA 1DDRA 3JTWA 3QL0A 3DGAA 1LY4A 1S3YA 3INVA 5HQZA 2ITHA 4M6KA 4KL9A 4X5FA 4P68A 4XT5A 3FY8X 2BLCA 1RA3A 2ZZAA 1RB3A 4KM0A 2W3WA 4I1NA 2W9GA 4KD7A 3K74A 1MVTA 3FREX 5E8QA 3L3RA 2L28A 3IX9A 2ANOA 2KGKA 2XW7A 5ECXA 2OBCA 1KLKA 1DLRA 5DXVA 3QLYA 2W9HA 5FDAA 3JWMA 5EAJA 5HT4A 3TQAA 3D84X 1RB2A 4ELFA 2D5NA 3NZBX 1J3JA 4DPDA 4HOEA 4PTHA 3JWFA 1RX2A 1LUDA 3JWCA 4KNEA 1RX3A 3FQZA 2QK8A 3KJRA 3I8AX 5ECCA 1BOZA 1RC4A 4KJKA 7DFRA 5DFRA 3F91A 3JW5A 3KY8A 3M09A 2W3BA 4HOFA 1U72A 2C2TA 2GD9A 3NXVA 3Q1HA 4XE6X 3EEJA 3IROA 4NX6A 3TQ8A 4KM2A 3DRCA 3FS6A 1DRAA 2FZJA 3TD8A 3IA4A 1DYHA 4IXFX 3NTZA 1PD8A 1YHOA 3QLRA 2HM9A 1AO8A 4ECKA 2D0KA 1SEJA 1RF7A 3K47A 3FRFX 4QLGA 3F0QX 2O7PA 4X5JA 2INQA 1OHKA 4XRBA 4ELEA 3QFXA 4NX7A 3NXTA 4KEBA 1RX1A 4QI9A 1MVSA 1RX4A 1OHJA 3K2HA 3QLWA 1BZFA 1TDRA 4DDRA 4DPHA 5HVBA 1RA9A 4QLFA 1VDRA 3IRNA 4LAHX 3FYWX 4OR7A 5HVEA 3FRDX 3TQ9A 4H97A 4EILA 4DFRA 3KJSA 3F0VX 4RGCA 3D80A 3GI2A 3FL9A 4Q0EA 3S9UA 3DG8A 5HSRA 1RD7A 5U26A 2HQPA 5HI6A 5CCCA 4PSTA 4M6JA 1D1GA 3RG9A 4KY8A 1ZDRA 1S3UA 1M79A 4G95A 3UM6A 1DYJA 4X5HA 4P3RA 1RX7A 4QLEA 5JA3A 1S3WA 4EJ1A 3DL5A 3EIGA 3QYLA 1DR7A 1DDSA 2H2QA 3QLXA 3EX8A 4KYAA 1AI9A 1U71A 3SRRX 1RA1A 4QHVA 1RX9A 4CD2A 3ZPGA 3SRQX 3DAUA 3NZCX 3OCHA 3GHVA 1DRBA 3SA1A 4GH8A 4KFJA 1AOEA 3QL3A 3SGYA 6DFRA 3QLSA 5CC9A 1IA1A 2JYBA 4ELBA 3IA5A 3FYVX 3KGYA 5HQYA 2ANQA 4ELHA 4P66A 4TU5X 4OSGA 3NU0A 1IA4A 1JOMA 3SRWX 3CSEA 4PSYA 3JWKA 4LAEX 2DRCA 1RA2A 1J3KA 3QYOA 2W9TA 3VCOA 4G3MA 4EIZA 4XECX 1CZ3A 3DATA 3HBBA 3F0BX 3I3RA 4M2XA 4KLXA 3UM5A 4Q6AA 3FQVA 1DR4A 3QLZA 4FGHA 4XT4A 3N0HA 1CD2A 1PDBA 2AZNA 3CL9A 3S3VA 1KMSA 3FQOA 2P4GA 5JG0X 1HFPA 3JVXA 1HFRA 2C2SA 3EELA 5HF0X 4FGGA 3GHCA 3LG4A 3OAFA 1RE7A 2OIPA 3NXRA 1DRHA 4PDJA 1DAJA 8DFRA 3TQBA 2BL9A 3SH2A 3SA2A 4I13A 2CIGA 3F8YA 5HPBA 3S7AA 3NZDA 2FZHA 1J3IA 1DIUA 4M6LA 1DR2A 1DG5A 3F8ZA 4QJZD 1DF7A 1DYIA 3DFRA 3GHWA 4XT7A 4DP3A 3ZPCA 4HA9A 1IA3A 1HFQA 2W3VA 4Q0DA 2W3AA 4FHBA 3JSUA 4XT8A 2BLBA 4XT6A 3CLBA 1PD9A 3M08A 4HA7A 1RX5A 3R33A 1KMVA 1RA8A 3EEMA 3HJ3A 3NXYA 3QG2A 4KBNA 3FY9X 1DHFA 3NZ6X 3NZAX 1LY3A 3JW3A 3SRUX 4KJJA 2LF1A 1DG8A 3K45A 4KAKA
chains in the Genus database with same CATH superfamily
1DREA 3SR5X 1DHJA 3FRAX 4P3QA 2W3MA 1DR3A 1DHIA 1RG7A 3SRSX 3QGTA 1E26A 1DYRA 3FQ0A 4KJLA 3IRMA 4X5GA 1RX6A 1JUVA 4H95A 1RH3A 4LEKX 1RX8A 4IXED 4M7VA 1DR1A 3E0BA 3NZ9X 1DISA 2DHFA 4X5IA 4QJCA 1DR5A 3F0UX 1JOLA 1DRFA 1M78A 5HF2X 3ROAA 3EEKA 3SQYX 2B3ZA 5HUIA 1VJ3A 2BLAA 1DR6A 3GYFA 4PTJA 1U70A 4HOGA 2W9SA 4H96A 4M7UA 4IXGX 3DL6A 4H98A 2FZIA 3FRBX 2G6VA 4Q67A 4KY4A 3FL8A 1IA2A 1S3VA 5HT5A 3NXOA 3UM8A 1DG7A 2CD2A 3CD2A 3KFYA 1DLSA 5HSUA 3FQFA 4LAGX 4EIGA 1M7AA 3NXXA 3SAIA 3NRRA 4G8ZX 3FQCA 3F0SX 5U27A 3RO9A 1QZFA 3F0XX 2HXVA 4PSSA 4ELGA 1DDRA 3JTWA 3QL0A 3DGAA 1LY4A 1S3YA 3INVA 5HQZA 2ITHA 4M6KA 4KL9A 4X5FA 4P68A 4XT5A 3FY8X 2BLCA 1RA3A 2ZZAA 1RB3A 4KM0A 2W3WA 4I1NA 2W9GA 4KD7A 3K74A 1MVTA 3FREX 5E8QA 3L3RA 2L28A 3IX9A 2ANOA 2KGKA 2XW7A 5ECXA 2OBCA 1KLKA 1DLRA 5DXVA 3QLYA 2W9HA 5FDAA 3JWMA 5EAJA 5HT4A 3TQAA 3D84X 1RB2A 4ELFA 2D5NA 3NZBX 1J3JA 4DPDA 4HOEA 4PTHA 3JWFA 1RX2A 1LUDA 3JWCA 4KNEA 1RX3A 3FQZA 2QK8A 3KJRA 3I8AX 5ECCA 1BOZA 1RC4A 4KJKA 7DFRA 5DFRA 3F91A 3JW5A 3KY8A 3M09A 2W3BA 4HOFA 1U72A 2C2TA 2GD9A 3NXVA 3Q1HA 4XE6X 3EEJA 3IROA 4NX6A 3TQ8A 4KM2A 3DRCA 3FS6A 1DRAA 2FZJA 3TD8A 3IA4A 1DYHA 4IXFX 3NTZA 1PD8A 1YHOA 3QLRA 2HM9A 1AO8A 4ECKA 2D0KA 1SEJA 1RF7A 3K47A 3FRFX 4QLGA 3F0QX 2O7PA 4X5JA 2INQA 1OHKA 4XRBA 4ELEA 3QFXA 4NX7A 3NXTA 4KEBA 1RX1A 4QI9A 1MVSA 1RX4A 1OHJA 3K2HA 3QLWA 1BZFA 1TDRA 4DDRA 4DPHA 5HVBA 1RA9A 4QLFA 1VDRA 3IRNA 4LAHX 3FYWX 4OR7A 5HVEA 3FRDX 3TQ9A 4H97A 4EILA 4DFRA 3KJSA 3F0VX 4RGCA 3D80A 3GI2A 3FL9A 4Q0EA 3S9UA 3DG8A 5HSRA 1RD7A 5U26A 2HQPA 5HI6A 5CCCA 4PSTA 4M6JA 1D1GA 3RG9A 4KY8A 1ZDRA 1S3UA 1M79A 4G95A 3UM6A 1DYJA 4X5HA 4P3RA 1RX7A 4QLEA 5JA3A 1S3WA 4EJ1A 3DL5A 3EIGA 3QYLA 1DR7A 1DDSA 2H2QA 3QLXA 3EX8A 4KYAA 1AI9A 1U71A 3SRRX 1RA1A 4QHVA 1RX9A 4CD2A 3ZPGA 3SRQX 3DAUA 3NZCX 3OCHA 3GHVA 1DRBA 3SA1A 4GH8A 4KFJA 1AOEA 3QL3A 3SGYA 6DFRA 3QLSA 5CC9A 1IA1A 2JYBA 4ELBA 3IA5A 3FYVX 3KGYA 5HQYA 2ANQA 4ELHA 4P66A 4TU5X 4OSGA 3NU0A 1IA4A 1JOMA 3SRWX 3CSEA 4PSYA 3JWKA 4LAEX 2DRCA 1RA2A 1J3KA 3QYOA 2W9TA 3VCOA 4G3MA 4EIZA 4XECX 1CZ3A 3DATA 3HBBA 3F0BX 3I3RA 4M2XA 4KLXA 3UM5A 4Q6AA 3FQVA 1DR4A 3QLZA 4FGHA 4XT4A 3N0HA 1CD2A 1PDBA 2AZNA 3CL9A 3S3VA 1KMSA 3FQOA 2P4GA 5JG0X 1HFPA 3JVXA 1HFRA 2C2SA 3EELA 5HF0X 4FGGA 3GHCA 3LG4A 3OAFA 1RE7A 2OIPA 3NXRA 1DRHA 4PDJA 1DAJA 8DFRA 3TQBA 2BL9A 3SH2A 3SA2A 4I13A 2CIGA 3F8YA 5HPBA 3S7AA 3NZDA 2FZHA 1J3IA 1DIUA 4M6LA 1DR2A 1DG5A 3F8ZA 4QJZD 1DF7A 1DYIA 3DFRA 3GHWA 4XT7A 4DP3A 3ZPCA 4HA9A 1IA3A 1HFQA 2W3VA 4Q0DA 2W3AA 4FHBA 3JSUA 4XT8A 2BLBA 4XT6A 3CLBA 1PD9A 3M08A 4HA7A 1RX5A 3R33A 1KMVA 1RA8A 3EEMA 3HJ3A 3NXYA 3QG2A 4KBNA 3FY9X 1DHFA 3NZ6X 3NZAX 1LY3A 3JW3A 3SRUX 4KJJA 2LF1A 1DG8A 3K45A 4KAKA
chains in the Genus database with same CATH topology
1DREA 3SR5X 1DHJA 3FRAX 4P3QA 2W3MA 1DR3A 1DHIA 1RG7A 3SRSX 3QGTA 1E26A 1DYRA 3FQ0A 4KJLA 3IRMA 4X5GA 1RX6A 1JUVA 4H95A 1RH3A 4LEKX 1RX8A 4IXED 4M7VA 1DR1A 3E0BA 3NZ9X 1DISA 2DHFA 4X5IA 4QJCA 1DR5A 3F0UX 1JOLA 1DRFA 1M78A 5HF2X 3ROAA 3EEKA 3SQYX 2B3ZA 5HUIA 1VJ3A 2BLAA 1DR6A 3GYFA 4PTJA 1U70A 4HOGA 2W9SA 4H96A 4M7UA 4IXGX 3DL6A 4H98A 2FZIA 3FRBX 2G6VA 4Q67A 4KY4A 3FL8A 1IA2A 1S3VA 5HT5A 3NXOA 3UM8A 1DG7A 2CD2A 3CD2A 3KFYA 1DLSA 5HSUA 3FQFA 4LAGX 4EIGA 1M7AA 3NXXA 3SAIA 3NRRA 4G8ZX 3FQCA 3F0SX 5U27A 3RO9A 1QZFA 3F0XX 2HXVA 4PSSA 4ELGA 1DDRA 3JTWA 3QL0A 3DGAA 1LY4A 1S3YA 3INVA 5HQZA 2ITHA 4M6KA 4KL9A 4X5FA 4P68A 4XT5A 3FY8X 2BLCA 1RA3A 2ZZAA 1RB3A 4KM0A 2W3WA 4I1NA 2W9GA 4KD7A 3K74A 1MVTA 3FREX 5E8QA 3L3RA 2L28A 3IX9A 2ANOA 2KGKA 2XW7A 5ECXA 2OBCA 1KLKA 1DLRA 5DXVA 3QLYA 2W9HA 5FDAA 3JWMA 5EAJA 5HT4A 3TQAA 3D84X 1RB2A 4ELFA 2D5NA 3NZBX 1J3JA 4DPDA 4HOEA 4PTHA 3JWFA 1RX2A 1LUDA 3JWCA 4KNEA 1RX3A 3FQZA 2QK8A 3KJRA 3I8AX 5ECCA 1BOZA 1RC4A 4KJKA 7DFRA 5DFRA 3F91A 3JW5A 3KY8A 3M09A 2W3BA 4HOFA 1U72A 2C2TA 2GD9A 3NXVA 3Q1HA 4XE6X 3EEJA 3IROA 4NX6A 3TQ8A 4KM2A 3DRCA 3FS6A 1DRAA 2FZJA 3TD8A 3IA4A 1DYHA 4IXFX 3NTZA 1PD8A 1YHOA 3QLRA 2HM9A 1AO8A 4ECKA 2D0KA 1SEJA 1RF7A 3K47A 3FRFX 4QLGA 3F0QX 2O7PA 4X5JA 2INQA 1OHKA 4XRBA 4ELEA 3QFXA 4NX7A 3NXTA 4KEBA 1RX1A 4QI9A 1MVSA 1RX4A 1OHJA 3K2HA 3QLWA 1BZFA 1TDRA 4DDRA 4DPHA 5HVBA 1RA9A 4QLFA 1VDRA 3IRNA 4LAHX 3FYWX 4OR7A 5HVEA 3FRDX 3TQ9A 4H97A 4EILA 4DFRA 3KJSA 3F0VX 4RGCA 3D80A 3GI2A 3FL9A 4Q0EA 3S9UA 3DG8A 5HSRA 1RD7A 5U26A 2HQPA 5HI6A 5CCCA 4PSTA 4M6JA 1D1GA 3RG9A 4KY8A 1ZDRA 1S3UA 1M79A 4G95A 3UM6A 1DYJA 4X5HA 4P3RA 1RX7A 4QLEA 5JA3A 1S3WA 4EJ1A 3DL5A 3EIGA 3QYLA 1DR7A 1DDSA 2H2QA 3QLXA 3EX8A 4KYAA 1AI9A 1U71A 3SRRX 1RA1A 4QHVA 1RX9A 4CD2A 3ZPGA 3SRQX 3DAUA 3NZCX 3OCHA 3GHVA 1DRBA 3SA1A 4GH8A 4KFJA 1AOEA 3QL3A 3SGYA 6DFRA 3QLSA 5CC9A 1IA1A 2JYBA 4ELBA 3IA5A 3FYVX 3KGYA 5HQYA 2ANQA 4ELHA 4P66A 4TU5X 4OSGA 3NU0A 1IA4A 1JOMA 3SRWX 3CSEA 4PSYA 3JWKA 4LAEX 2DRCA 1RA2A 1J3KA 3QYOA 2W9TA 3VCOA 4G3MA 4EIZA 4XECX 1CZ3A 3DATA 3HBBA 3F0BX 3I3RA 4M2XA 4KLXA 3UM5A 4Q6AA 3FQVA 1DR4A 3QLZA 4FGHA 4XT4A 3N0HA 1CD2A 1PDBA 2AZNA 3CL9A 3S3VA 1KMSA 3FQOA 2P4GA 5JG0X 1HFPA 3JVXA 1HFRA 2C2SA 3EELA 5HF0X 4FGGA 3GHCA 3LG4A 3OAFA 1RE7A 2OIPA 3NXRA 1DRHA 4PDJA 1DAJA 8DFRA 3TQBA 2BL9A 3SH2A 3SA2A 4I13A 2CIGA 3F8YA 5HPBA 3S7AA 3NZDA 2FZHA 1J3IA 1DIUA 4M6LA 1DR2A 1DG5A 3F8ZA 4QJZD 1DF7A 1DYIA 3DFRA 3GHWA 4XT7A 4DP3A 3ZPCA 4HA9A 1IA3A 1HFQA 2W3VA 4Q0DA 2W3AA 4FHBA 3JSUA 4XT8A 2BLBA 4XT6A 3CLBA 1PD9A 3M08A 4HA7A 1RX5A 3R33A 1KMVA 1RA8A 3EEMA 3HJ3A 3NXYA 3QG2A 4KBNA 3FY9X 1DHFA 3NZ6X 3NZAX 1LY3A 3JW3A 3SRUX 4KJJA 2LF1A 1DG8A 3K45A 4KAKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DRE A;  3SR5 X;  1DHJ A;  3FRA X;  4P3Q A;  2W3M A;  1DR3 A;  1DHI A;  1RG7 A;  3SRS X;  3QGT A;  1E26 A;  1DYR A;  3FQ0 A;  4KJL A;  3IRM A;  4X5G A;  1RX6 A;  1JUV A;  4H95 A;  1RH3 A;  4LEK X;  1RX8 A;  4IXE D;  4M7V A;  1DR1 A;  3E0B A;  3NZ9 X;  1DIS A;  2DHF A;  4X5I A;  4QJC A;  1DR5 A;  3F0U X;  1JOL A;  1DRF A;  1M78 A;  5HF2 X;  3ROA A;  3EEK A;  3SQY X;  2B3Z A;  5HUI A;  1VJ3 A;  2BLA A;  1DR6 A;  3GYF A;  4PTJ A;  1U70 A;  4HOG A;  2W9S A;  4H96 A;  4M7U A;  4IXG X;  3DL6 A;  4H98 A;  2FZI A;  3FRB X;  2G6V A;  4Q67 A;  4KY4 A;  3FL8 A;  1IA2 A;  1S3V A;  5HT5 A;  3NXO A;  3UM8 A;  1DG7 A;  2CD2 A;  3CD2 A;  3KFY A;  1DLS A;  5HSU A;  3FQF A;  4LAG X;  4EIG A;  1M7A A;  3NXX A;  3SAI A;  3NRR A;  4G8Z X;  3FQC A;  3F0S X;  5U27 A;  3RO9 A;  1QZF A;  3F0X X;  2HXV A;  4PSS A;  4ELG A;  1DDR A;  3JTW A;  3QL0 A;  3DGA A;  1LY4 A;  1S3Y A;  3INV A;  5HQZ A;  2ITH A;  4M6K A;  4KL9 A;  4X5F A;  4P68 A;  4XT5 A;  3FY8 X;  2BLC A;  1RA3 A;  2ZZA A;  1RB3 A;  4KM0 A;  2W3W A;  4I1N A;  2W9G A;  4KD7 A;  3K74 A;  1MVT A;  3FRE X;  5E8Q A;  3L3R A;  2L28 A;  3IX9 A;  2ANO A;  2KGK A;  2XW7 A;  5ECX A;  2OBC A;  1KLK A;  1DLR A;  5DXV A;  3QLY A;  2W9H A;  5FDA A;  3JWM A;  5EAJ A;  5HT4 A;  3TQA A;  3D84 X;  1RB2 A;  4ELF A;  2D5N A;  3NZB X;  1J3J A;  4DPD A;  4HOE A;  4PTH A;  3JWF A;  1RX2 A;  1LUD A;  3JWC A;  4KNE A;  1RX3 A;  3FQZ A;  2QK8 A;  3KJR A;  3I8A X;  5ECC A;  1BOZ A;  1RC4 A;  4KJK A;  7DFR A;  5DFR A;  3F91 A;  3JW5 A;  3KY8 A;  3M09 A;  2W3B A;  4HOF A;  1U72 A;  2C2T A;  2GD9 A;  3NXV A;  3Q1H A;  4XE6 X;  3EEJ A;  3IRO A;  4NX6 A;  3TQ8 A;  4KM2 A;  3DRC A;  3FS6 A;  1DRA A;  2FZJ A;  3TD8 A;  3IA4 A;  1DYH A;  4IXF X;  3NTZ A;  1PD8 A;  1YHO A;  3QLR A;  2HM9 A;  1AO8 A;  4ECK A;  2D0K A;  1SEJ A;  1RF7 A;  3K47 A;  3FRF X;  4QLG A;  3F0Q X;  2O7P A;  4X5J A;  2INQ A;  1OHK A;  4XRB A;  4ELE A;  3QFX A;  4NX7 A;  3NXT A;  4KEB A;  1RX1 A;  4QI9 A;  1MVS A;  1RX4 A;  1OHJ A;  3K2H A;  3QLW A;  1BZF A;  1TDR A;  4DDR A;  4DPH A;  5HVB A;  1RA9 A;  4QLF A;  1VDR A;  3IRN A;  4LAH X;  3FYW X;  4OR7 A;  5HVE A;  3FRD X;  3TQ9 A;  4H97 A;  4EIL A;  4DFR A;  3KJS A;  3F0V X;  4RGC A;  3D80 A;  3GI2 A;  3FL9 A;  4Q0E A;  3S9U A;  3DG8 A;  5HSR A;  1RD7 A;  5U26 A;  2HQP A;  5HI6 A;  5CCC A;  4PST A;  4M6J A;  1D1G A;  3RG9 A;  4KY8 A;  1ZDR A;  1S3U A;  1M79 A;  4G95 A;  3UM6 A;  1DYJ A;  4X5H A;  4P3R A;  1RX7 A;  4QLE A;  5JA3 A;  1S3W A;  4EJ1 A;  3DL5 A;  3EIG A;  3QYL A;  1DR7 A;  1DDS A;  2H2Q A;  3QLX A;  3EX8 A;  4KYA A;  1AI9 A;  1U71 A;  3SRR X;  1RA1 A;  4QHV A;  1RX9 A;  4CD2 A;  3ZPG A;  3SRQ X;  3DAU A;  3NZC X;  3OCH A;  3GHV A;  1DRB A;  3SA1 A;  4GH8 A;  4KFJ A;  1AOE A;  3QL3 A;  3SGY A;  6DFR A;  3QLS A;  5CC9 A;  1IA1 A;  2JYB A;  4ELB A;  3IA5 A;  3FYV X;  3KGY A;  5HQY A;  2ANQ A;  4ELH A;  4P66 A;  4TU5 X;  4OSG A;  3NU0 A;  1IA4 A;  1JOM A;  3SRW X;  3CSE A;  4PSY A;  3JWK A;  4LAE X;  2DRC A;  1RA2 A;  1J3K A;  3QYO A;  2W9T A;  3VCO A;  4G3M A;  4EIZ A;  4XEC X;  1CZ3 A;  3DAT A;  3HBB A;  3F0B X;  3I3R A;  4M2X A;  4KLX A;  3UM5 A;  4Q6A A;  3FQV A;  1DR4 A;  3QLZ A;  4FGH A;  4XT4 A;  3N0H A;  1CD2 A;  1PDB A;  2AZN A;  3CL9 A;  3S3V A;  1KMS A;  3FQO A;  2P4G A;  5JG0 X;  1HFP A;  3JVX A;  1HFR A;  2C2S A;  3EEL A;  5HF0 X;  4FGG A;  3GHC A;  3LG4 A;  3OAF A;  1RE7 A;  2OIP A;  3NXR A;  1DRH A;  4PDJ A;  1DAJ A;  8DFR A;  3TQB A;  2BL9 A;  3SH2 A;  3SA2 A;  4I13 A;  2CIG A;  3F8Y A;  5HPB A;  3S7A A;  3NZD A;  2FZH A;  1J3I A;  1DIU A;  4M6L A;  1DR2 A;  1DG5 A;  3F8Z A;  4QJZ D;  1DF7 A;  1DYI A;  3DFR A;  3GHW A;  4XT7 A;  4DP3 A;  3ZPC A;  4HA9 A;  1IA3 A;  1HFQ A;  2W3V A;  4Q0D A;  2W3A A;  4FHB A;  3JSU A;  4XT8 A;  2BLB A;  4XT6 A;  3CLB A;  1PD9 A;  3M08 A;  4HA7 A;  1RX5 A;  3R33 A;  1KMV A;  1RA8 A;  3EEM A;  3HJ3 A;  3NXY A;  3QG2 A;  4KBN A;  3FY9 X;  1DHF A;  3NZ6 X;  3NZA X;  1LY3 A;  3JW3 A;  3SRU X;  4KJJ A;  2LF1 A;  1DG8 A;  3K45 A;  4KAK A; 
#chains in the Genus database with same CATH topology
 1DRE A;  3SR5 X;  1DHJ A;  3FRA X;  4P3Q A;  2W3M A;  1DR3 A;  1DHI A;  1RG7 A;  3SRS X;  3QGT A;  1E26 A;  1DYR A;  3FQ0 A;  4KJL A;  3IRM A;  4X5G A;  1RX6 A;  1JUV A;  4H95 A;  1RH3 A;  4LEK X;  1RX8 A;  4IXE D;  4M7V A;  1DR1 A;  3E0B A;  3NZ9 X;  1DIS A;  2DHF A;  4X5I A;  4QJC A;  1DR5 A;  3F0U X;  1JOL A;  1DRF A;  1M78 A;  5HF2 X;  3ROA A;  3EEK A;  3SQY X;  2B3Z A;  5HUI A;  1VJ3 A;  2BLA A;  1DR6 A;  3GYF A;  4PTJ A;  1U70 A;  4HOG A;  2W9S A;  4H96 A;  4M7U A;  4IXG X;  3DL6 A;  4H98 A;  2FZI A;  3FRB X;  2G6V A;  4Q67 A;  4KY4 A;  3FL8 A;  1IA2 A;  1S3V A;  5HT5 A;  3NXO A;  3UM8 A;  1DG7 A;  2CD2 A;  3CD2 A;  3KFY A;  1DLS A;  5HSU A;  3FQF A;  4LAG X;  4EIG A;  1M7A A;  3NXX A;  3SAI A;  3NRR A;  4G8Z X;  3FQC A;  3F0S X;  5U27 A;  3RO9 A;  1QZF A;  3F0X X;  2HXV A;  4PSS A;  4ELG A;  1DDR A;  3JTW A;  3QL0 A;  3DGA A;  1LY4 A;  1S3Y A;  3INV A;  5HQZ A;  2ITH A;  4M6K A;  4KL9 A;  4X5F A;  4P68 A;  4XT5 A;  3FY8 X;  2BLC A;  1RA3 A;  2ZZA A;  1RB3 A;  4KM0 A;  2W3W A;  4I1N A;  2W9G A;  4KD7 A;  3K74 A;  1MVT A;  3FRE X;  5E8Q A;  3L3R A;  2L28 A;  3IX9 A;  2ANO A;  2KGK A;  2XW7 A;  5ECX A;  2OBC A;  1KLK A;  1DLR A;  5DXV A;  3QLY A;  2W9H A;  5FDA A;  3JWM A;  5EAJ A;  5HT4 A;  3TQA A;  3D84 X;  1RB2 A;  4ELF A;  2D5N A;  3NZB X;  1J3J A;  4DPD A;  4HOE A;  4PTH A;  3JWF A;  1RX2 A;  1LUD A;  3JWC A;  4KNE A;  1RX3 A;  3FQZ A;  2QK8 A;  3KJR A;  3I8A X;  5ECC A;  1BOZ A;  1RC4 A;  4KJK A;  7DFR A;  5DFR A;  3F91 A;  3JW5 A;  3KY8 A;  3M09 A;  2W3B A;  4HOF A;  1U72 A;  2C2T A;  2GD9 A;  3NXV A;  3Q1H A;  4XE6 X;  3EEJ A;  3IRO A;  4NX6 A;  3TQ8 A;  4KM2 A;  3DRC A;  3FS6 A;  1DRA A;  2FZJ A;  3TD8 A;  3IA4 A;  1DYH A;  4IXF X;  3NTZ A;  1PD8 A;  1YHO A;  3QLR A;  2HM9 A;  1AO8 A;  4ECK A;  2D0K A;  1SEJ A;  1RF7 A;  3K47 A;  3FRF X;  4QLG A;  3F0Q X;  2O7P A;  4X5J A;  2INQ A;  1OHK A;  4XRB A;  4ELE A;  3QFX A;  4NX7 A;  3NXT A;  4KEB A;  1RX1 A;  4QI9 A;  1MVS A;  1RX4 A;  1OHJ A;  3K2H A;  3QLW A;  1BZF A;  1TDR A;  4DDR A;  4DPH A;  5HVB A;  1RA9 A;  4QLF A;  1VDR A;  3IRN A;  4LAH X;  3FYW X;  4OR7 A;  5HVE A;  3FRD X;  3TQ9 A;  4H97 A;  4EIL A;  4DFR A;  3KJS A;  3F0V X;  4RGC A;  3D80 A;  3GI2 A;  3FL9 A;  4Q0E A;  3S9U A;  3DG8 A;  5HSR A;  1RD7 A;  5U26 A;  2HQP A;  5HI6 A;  5CCC A;  4PST A;  4M6J A;  1D1G A;  3RG9 A;  4KY8 A;  1ZDR A;  1S3U A;  1M79 A;  4G95 A;  3UM6 A;  1DYJ A;  4X5H A;  4P3R A;  1RX7 A;  4QLE A;  5JA3 A;  1S3W A;  4EJ1 A;  3DL5 A;  3EIG A;  3QYL A;  1DR7 A;  1DDS A;  2H2Q A;  3QLX A;  3EX8 A;  4KYA A;  1AI9 A;  1U71 A;  3SRR X;  1RA1 A;  4QHV A;  1RX9 A;  4CD2 A;  3ZPG A;  3SRQ X;  3DAU A;  3NZC X;  3OCH A;  3GHV A;  1DRB A;  3SA1 A;  4GH8 A;  4KFJ A;  1AOE A;  3QL3 A;  3SGY A;  6DFR A;  3QLS A;  5CC9 A;  1IA1 A;  2JYB A;  4ELB A;  3IA5 A;  3FYV X;  3KGY A;  5HQY A;  2ANQ A;  4ELH A;  4P66 A;  4TU5 X;  4OSG A;  3NU0 A;  1IA4 A;  1JOM A;  3SRW X;  3CSE A;  4PSY A;  3JWK A;  4LAE X;  2DRC A;  1RA2 A;  1J3K A;  3QYO A;  2W9T A;  3VCO A;  4G3M A;  4EIZ A;  4XEC X;  1CZ3 A;  3DAT A;  3HBB A;  3F0B X;  3I3R A;  4M2X A;  4KLX A;  3UM5 A;  4Q6A A;  3FQV A;  1DR4 A;  3QLZ A;  4FGH A;  4XT4 A;  3N0H A;  1CD2 A;  1PDB A;  2AZN A;  3CL9 A;  3S3V A;  1KMS A;  3FQO A;  2P4G A;  5JG0 X;  1HFP A;  3JVX A;  1HFR A;  2C2S A;  3EEL A;  5HF0 X;  4FGG A;  3GHC A;  3LG4 A;  3OAF A;  1RE7 A;  2OIP A;  3NXR A;  1DRH A;  4PDJ A;  1DAJ A;  8DFR A;  3TQB A;  2BL9 A;  3SH2 A;  3SA2 A;  4I13 A;  2CIG A;  3F8Y A;  5HPB A;  3S7A A;  3NZD A;  2FZH A;  1J3I A;  1DIU A;  4M6L A;  1DR2 A;  1DG5 A;  3F8Z A;  4QJZ D;  1DF7 A;  1DYI A;  3DFR A;  3GHW A;  4XT7 A;  4DP3 A;  3ZPC A;  4HA9 A;  1IA3 A;  1HFQ A;  2W3V A;  4Q0D A;  2W3A A;  4FHB A;  3JSU A;  4XT8 A;  2BLB A;  4XT6 A;  3CLB A;  1PD9 A;  3M08 A;  4HA7 A;  1RX5 A;  3R33 A;  1KMV A;  1RA8 A;  3EEM A;  3HJ3 A;  3NXY A;  3QG2 A;  4KBN A;  3FY9 X;  1DHF A;  3NZ6 X;  3NZA X;  1LY3 A;  3JW3 A;  3SRU X;  4KJJ A;  2LF1 A;  1DG8 A;  3K45 A;  4KAK A; 
#chains in the Genus database with same CATH homology
 1DRE A;  3SR5 X;  1DHJ A;  3FRA X;  4P3Q A;  2W3M A;  1DR3 A;  1DHI A;  1RG7 A;  3SRS X;  3QGT A;  1E26 A;  1DYR A;  3FQ0 A;  4KJL A;  3IRM A;  4X5G A;  1RX6 A;  1JUV A;  4H95 A;  1RH3 A;  4LEK X;  1RX8 A;  4IXE D;  4M7V A;  1DR1 A;  3E0B A;  3NZ9 X;  1DIS A;  2DHF A;  4X5I A;  4QJC A;  1DR5 A;  3F0U X;  1JOL A;  1DRF A;  1M78 A;  5HF2 X;  3ROA A;  3EEK A;  3SQY X;  2B3Z A;  5HUI A;  1VJ3 A;  2BLA A;  1DR6 A;  3GYF A;  4PTJ A;  1U70 A;  4HOG A;  2W9S A;  4H96 A;  4M7U A;  4IXG X;  3DL6 A;  4H98 A;  2FZI A;  3FRB X;  2G6V A;  4Q67 A;  4KY4 A;  3FL8 A;  1IA2 A;  1S3V A;  5HT5 A;  3NXO A;  3UM8 A;  1DG7 A;  2CD2 A;  3CD2 A;  3KFY A;  1DLS A;  5HSU A;  3FQF A;  4LAG X;  4EIG A;  1M7A A;  3NXX A;  3SAI A;  3NRR A;  4G8Z X;  3FQC A;  3F0S X;  5U27 A;  3RO9 A;  1QZF A;  3F0X X;  2HXV A;  4PSS A;  4ELG A;  1DDR A;  3JTW A;  3QL0 A;  3DGA A;  1LY4 A;  1S3Y A;  3INV A;  5HQZ A;  2ITH A;  4M6K A;  4KL9 A;  4X5F A;  4P68 A;  4XT5 A;  3FY8 X;  2BLC A;  1RA3 A;  2ZZA A;  1RB3 A;  4KM0 A;  2W3W A;  4I1N A;  2W9G A;  4KD7 A;  3K74 A;  1MVT A;  3FRE X;  5E8Q A;  3L3R A;  2L28 A;  3IX9 A;  2ANO A;  2KGK A;  2XW7 A;  5ECX A;  2OBC A;  1KLK A;  1DLR A;  5DXV A;  3QLY A;  2W9H A;  5FDA A;  3JWM A;  5EAJ A;  5HT4 A;  3TQA A;  3D84 X;  1RB2 A;  4ELF A;  2D5N A;  3NZB X;  1J3J A;  4DPD A;  4HOE A;  4PTH A;  3JWF A;  1RX2 A;  1LUD A;  3JWC A;  4KNE A;  1RX3 A;  3FQZ A;  2QK8 A;  3KJR A;  3I8A X;  5ECC A;  1BOZ A;  1RC4 A;  4KJK A;  7DFR A;  5DFR A;  3F91 A;  3JW5 A;  3KY8 A;  3M09 A;  2W3B A;  4HOF A;  1U72 A;  2C2T A;  2GD9 A;  3NXV A;  3Q1H A;  4XE6 X;  3EEJ A;  3IRO A;  4NX6 A;  3TQ8 A;  4KM2 A;  3DRC A;  3FS6 A;  1DRA A;  2FZJ A;  3TD8 A;  3IA4 A;  1DYH A;  4IXF X;  3NTZ A;  1PD8 A;  1YHO A;  3QLR A;  2HM9 A;  1AO8 A;  4ECK A;  2D0K A;  1SEJ A;  1RF7 A;  3K47 A;  3FRF X;  4QLG A;  3F0Q X;  2O7P A;  4X5J A;  2INQ A;  1OHK A;  4XRB A;  4ELE A;  3QFX A;  4NX7 A;  3NXT A;  4KEB A;  1RX1 A;  4QI9 A;  1MVS A;  1RX4 A;  1OHJ A;  3K2H A;  3QLW A;  1BZF A;  1TDR A;  4DDR A;  4DPH A;  5HVB A;  1RA9 A;  4QLF A;  1VDR A;  3IRN A;  4LAH X;  3FYW X;  4OR7 A;  5HVE A;  3FRD X;  3TQ9 A;  4H97 A;  4EIL A;  4DFR A;  3KJS A;  3F0V X;  4RGC A;  3D80 A;  3GI2 A;  3FL9 A;  4Q0E A;  3S9U A;  3DG8 A;  5HSR A;  1RD7 A;  5U26 A;  2HQP A;  5HI6 A;  5CCC A;  4PST A;  4M6J A;  1D1G A;  3RG9 A;  4KY8 A;  1ZDR A;  1S3U A;  1M79 A;  4G95 A;  3UM6 A;  1DYJ A;  4X5H A;  4P3R A;  1RX7 A;  4QLE A;  5JA3 A;  1S3W A;  4EJ1 A;  3DL5 A;  3EIG A;  3QYL A;  1DR7 A;  1DDS A;  2H2Q A;  3QLX A;  3EX8 A;  4KYA A;  1AI9 A;  1U71 A;  3SRR X;  1RA1 A;  4QHV A;  1RX9 A;  4CD2 A;  3ZPG A;  3SRQ X;  3DAU A;  3NZC X;  3OCH A;  3GHV A;  1DRB A;  3SA1 A;  4GH8 A;  4KFJ A;  1AOE A;  3QL3 A;  3SGY A;  6DFR A;  3QLS A;  5CC9 A;  1IA1 A;  2JYB A;  4ELB A;  3IA5 A;  3FYV X;  3KGY A;  5HQY A;  2ANQ A;  4ELH A;  4P66 A;  4TU5 X;  4OSG A;  3NU0 A;  1IA4 A;  1JOM A;  3SRW X;  3CSE A;  4PSY A;  3JWK A;  4LAE X;  2DRC A;  1RA2 A;  1J3K A;  3QYO A;  2W9T A;  3VCO A;  4G3M A;  4EIZ A;  4XEC X;  1CZ3 A;  3DAT A;  3HBB A;  3F0B X;  3I3R A;  4M2X A;  4KLX A;  3UM5 A;  4Q6A A;  3FQV A;  1DR4 A;  3QLZ A;  4FGH A;  4XT4 A;  3N0H A;  1CD2 A;  1PDB A;  2AZN A;  3CL9 A;  3S3V A;  1KMS A;  3FQO A;  2P4G A;  5JG0 X;  1HFP A;  3JVX A;  1HFR A;  2C2S A;  3EEL A;  5HF0 X;  4FGG A;  3GHC A;  3LG4 A;  3OAF A;  1RE7 A;  2OIP A;  3NXR A;  1DRH A;  4PDJ A;  1DAJ A;  8DFR A;  3TQB A;  2BL9 A;  3SH2 A;  3SA2 A;  4I13 A;  2CIG A;  3F8Y A;  5HPB A;  3S7A A;  3NZD A;  2FZH A;  1J3I A;  1DIU A;  4M6L A;  1DR2 A;  1DG5 A;  3F8Z A;  4QJZ D;  1DF7 A;  1DYI A;  3DFR A;  3GHW A;  4XT7 A;  4DP3 A;  3ZPC A;  4HA9 A;  1IA3 A;  1HFQ A;  2W3V A;  4Q0D A;  2W3A A;  4FHB A;  3JSU A;  4XT8 A;  2BLB A;  4XT6 A;  3CLB A;  1PD9 A;  3M08 A;  4HA7 A;  1RX5 A;  3R33 A;  1KMV A;  1RA8 A;  3EEM A;  3HJ3 A;  3NXY A;  3QG2 A;  4KBN A;  3FY9 X;  1DHF A;  3NZ6 X;  3NZA X;  1LY3 A;  3JW3 A;  3SRU X;  4KJJ A;  2LF1 A;  1DG8 A;  3K45 A;  4KAK A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...