5E8QA

Crystal structure of dhfr in 20% isopropanol
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLDKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solvent conditions control enzyme dynamics and catalysis
rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Dihydrofolate reductase
total genus 45
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2015-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 5e8qA00
3SA2A 3IA4A 2P4GA 1LY4A 3M09A 2W3VA 1KLKA 3TD8A 4QHVA 4PSTA 3QLYA 4FHBA 2W3MA 3KJRA 3IX9A 1RA3A 5EAJA 3VCOA 1HFRA 1CD2A 1S3VA 5DFRA 3TQ9A 4ELBA 4XT8A 4LAGX 3NZBX 3D80A 3S7AA 5E8QA 1S3WA 3JWFA 3DL6A 4HA9A 1S3UA 4KM0A 1M78A 2B3ZA 1DLRA 1J3JA 1RA2A 4IXGX 3OCHA 2D0KA 3TQAA 3RO9A 3QL0A 4M7UA 3QL3A 4H98A 5ECXA 1MVTA 1RX3A 5U27A 2O7PA 3NZ9X 2W9HA 3ZPCA 4KLXA 2HM9A 3I3RA 2INQA 1RA9A 1KMSA 4PTHA 1DLSA 3KFYA 2W9SA 2DHFA 2W3AA 3FQZA 4IXED 5HT4A 2QK8A 3KJSA 3SAIA 3K47A 1RA8A 3TQBA 3F0VX 3QLWA 1RG7A 4XECX 4IXFX 2W9GA 1U70A 1DYIA 3JW3A 1DYJA 3D84X 3NRRA 3FS6A 3DRCA 5JA3A 2JYBA 3NXRA 3F0SX 4LAEX 4PSYA 4NX7A 5HI6A 3FRDX 1DR7A 2BL9A 3NU0A 3F0UX 3FY9X 4QI9A 3S9UA 3GHVA 4FGHA 4QLEA 2H2QA 2W9TA 2KGKA 4PSSA 1RD7A 2D5NA 1IA2A 4DPDA 4FGGA 1U71A 2CD2A 1CZ3A 4XT7A 3S3VA 1DR2A 3JSUA 3GHCA 1DIUA 5HPBA 3FRAX 3QFXA 4KJJA 2ANQA 1DF7A 4QLFA 3SRQX 3FRBX 1JOLA 1RX5A 4XE6X 3KGYA 4P3RA 1DG5A 1OHJA 3CLBA 3FQFA 3NTZA 1DISA 1LY3A 4KY8A 3JWMA 3K2HA 2GD9A 4KFJA 1DHFA 2ANOA 3SRRX 1DDSA 4NX6A 2G6VA 1M79A 1E26A 4QJCA 3ZPGA 1RH3A 4QJZD 3M08A 4LAHX 5HF2X 1HFQA 4DDRA 2ITHA 3DFRA 2W3WA 4KL9A 3NXXA 3FQVA 3L3RA 2FZHA 1RX8A 3QLZA 1OHKA 1JOMA 4Q0DA 3QGTA 1RX9A 3F8YA 3JWCA 1DRBA 1DR6A 1RX4A 3FL9A 2OIPA 2C2TA 2LF1A 1KMVA 3FQOA 1VJ3A 5HQYA 1AOEA 3EEJA 2HXVA 4QLGA 1TDRA 3FY8X 3EELA 3GI2A 1DHJA 3SQYX 3HBBA 5DXVA 5ECCA 3F8ZA 4M6LA 4HOFA 4PDJA 5HSUA 2BLCA 1RB2A 4P3QA 2FZJA 4X5JA 1QZFA 4LEKX 3QLRA 4GH8A 8DFRA 3DG8A 3Q1HA 3EEKA 3F0QX 1DRFA 3HJ3A 1DYRA 3DATA 5HUIA 3KY8A 4ECKA 4KJLA 1AO8A 3FQ0A 3IROA 4KNEA 3DL5A 3F0BX 3FYWX 3JVXA 4X5FA 1RF7A 3QLSA 4Q6AA 3NZCX 1BZFA 4ELFA 4HOGA 4G8ZX 1D1GA 3SH2A 3QG2A 3GYFA 4EIZA 1DR5A 4G95A 3ROAA 6DFRA 1HFPA 3CD2A 1IA4A 3EX8A 5FDAA 4KAKA 1DRAA 3NZAX 3E0BA 3NXYA 1DR3A 1U72A 1S3YA 3NZDA 4XRBA 5CC9A 1VDRA 4I13A 5HSRA 4KYAA 3FRFX 3DGAA 4KJKA 3DAUA 4M6JA 4EILA 3GHWA 2BLBA 3SA1A 2OBCA 1IA3A 2C2SA 3R33A 4Q67A 3JW5A 4OSGA 3SRSX 3K74A 1DG8A 4X5IA 2XW7A 3SRUX 4ELEA 1SEJA 4XT4A 2AZNA 2ZZAA 1M7AA 3NXVA 1RX1A 3F0XX 2DRCA 5HT5A 1DDRA 1J3KA 1RX6A 4DP3A 3UM5A 3EEMA 2FZIA 4H95A 5JG0X 5HQZA 1PDBA 1RX7A 1ZDRA 1DG7A 1AI9A 3IRMA 1RC4A 4HA7A 4DFRA 5HF0X 2W3BA 3IA5A 4KBNA 4PTJA 3CSEA 3QYLA 1RE7A 3OAFA 3QLXA 4KY4A 4ELHA 3NXOA 4H97A 2HQPA 3RG9A 3SGYA 3SRWX 3JWKA 1BOZA 3EIGA 1DR1A 4P68A 5U26A 1YHOA 4H96A 4KM2A 1MVSA 1RA1A 3FREX 1JUVA 4KD7A 3CL9A 3NZ6X 3N0HA 4P66A 4ELGA 4G3MA 2CIGA 2BLAA 4RGCA 3I8AX 3SR5X 1IA1A 1DRHA 4CD2A 3FYVX 4HOEA 4I1NA 3UM8A 3JTWA 3FQCA 1DHIA 4Q0EA 1RB3A 3LG4A 4OR7A 4EIGA 5CCCA 3NXTA 4XT6A 4EJ1A 4KEBA 4M7VA 3F91A 3INVA 1DR4A 4X5GA 1LUDA 4TU5X 1DAJA 1DYHA 3QYOA 4XT5A 4X5HA 3TQ8A 1PD8A 1J3IA 5HVEA 1PD9A 1RX2A 4M2XA 3IRNA 4M6KA 3K45A 7DFRA 4DPHA 2L28A 5HVBA 1DREA 3UM6A 3FL8A
chains in the Genus database with same CATH superfamily
3SA2A 3IA4A 2P4GA 1LY4A 3M09A 2W3VA 1KLKA 3TD8A 4QHVA 4PSTA 3QLYA 4FHBA 2W3MA 3KJRA 3IX9A 1RA3A 5EAJA 3VCOA 1HFRA 1CD2A 1S3VA 5DFRA 3TQ9A 4ELBA 4XT8A 4LAGX 3NZBX 3D80A 3S7AA 5E8QA 1S3WA 3JWFA 3DL6A 4HA9A 1S3UA 4KM0A 1M78A 2B3ZA 1DLRA 1J3JA 1RA2A 4IXGX 3OCHA 2D0KA 3TQAA 3RO9A 3QL0A 4M7UA 3QL3A 4H98A 5ECXA 1MVTA 1RX3A 5U27A 2O7PA 3NZ9X 2W9HA 3ZPCA 4KLXA 2HM9A 3I3RA 2INQA 1RA9A 1KMSA 4PTHA 1DLSA 3KFYA 2W9SA 2DHFA 2W3AA 3FQZA 4IXED 5HT4A 2QK8A 3KJSA 3SAIA 3K47A 1RA8A 3TQBA 3F0VX 3QLWA 1RG7A 4XECX 4IXFX 2W9GA 1U70A 1DYIA 3JW3A 1DYJA 3D84X 3NRRA 3FS6A 3DRCA 5JA3A 2JYBA 3NXRA 3F0SX 4LAEX 4PSYA 4NX7A 5HI6A 3FRDX 1DR7A 2BL9A 3NU0A 3F0UX 3FY9X 4QI9A 3S9UA 3GHVA 4FGHA 4QLEA 2H2QA 2W9TA 2KGKA 4PSSA 1RD7A 2D5NA 1IA2A 4DPDA 4FGGA 1U71A 2CD2A 1CZ3A 4XT7A 3S3VA 1DR2A 3JSUA 3GHCA 1DIUA 5HPBA 3FRAX 3QFXA 4KJJA 2ANQA 1DF7A 4QLFA 3SRQX 3FRBX 1JOLA 1RX5A 4XE6X 3KGYA 4P3RA 1DG5A 1OHJA 3CLBA 3FQFA 3NTZA 1DISA 1LY3A 4KY8A 3JWMA 3K2HA 2GD9A 4KFJA 1DHFA 2ANOA 3SRRX 1DDSA 4NX6A 2G6VA 1M79A 1E26A 4QJCA 3ZPGA 1RH3A 4QJZD 3M08A 4LAHX 5HF2X 1HFQA 4DDRA 2ITHA 3DFRA 2W3WA 4KL9A 3NXXA 3FQVA 3L3RA 2FZHA 1RX8A 3QLZA 1OHKA 1JOMA 4Q0DA 3QGTA 1RX9A 3F8YA 3JWCA 1DRBA 1DR6A 1RX4A 3FL9A 2OIPA 2C2TA 2LF1A 1KMVA 3FQOA 1VJ3A 5HQYA 1AOEA 3EEJA 2HXVA 4QLGA 1TDRA 3FY8X 3EELA 3GI2A 1DHJA 3SQYX 3HBBA 5DXVA 5ECCA 3F8ZA 4M6LA 4HOFA 4PDJA 5HSUA 2BLCA 1RB2A 4P3QA 2FZJA 4X5JA 1QZFA 4LEKX 3QLRA 4GH8A 8DFRA 3DG8A 3Q1HA 3EEKA 3F0QX 1DRFA 3HJ3A 1DYRA 3DATA 5HUIA 3KY8A 4ECKA 4KJLA 1AO8A 3FQ0A 3IROA 4KNEA 3DL5A 3F0BX 3FYWX 3JVXA 4X5FA 1RF7A 3QLSA 4Q6AA 3NZCX 1BZFA 4ELFA 4HOGA 4G8ZX 1D1GA 3SH2A 3QG2A 3GYFA 4EIZA 1DR5A 4G95A 3ROAA 6DFRA 1HFPA 3CD2A 1IA4A 3EX8A 5FDAA 4KAKA 1DRAA 3NZAX 3E0BA 3NXYA 1DR3A 1U72A 1S3YA 3NZDA 4XRBA 5CC9A 1VDRA 4I13A 5HSRA 4KYAA 3FRFX 3DGAA 4KJKA 3DAUA 4M6JA 4EILA 3GHWA 2BLBA 3SA1A 2OBCA 1IA3A 2C2SA 3R33A 4Q67A 3JW5A 4OSGA 3SRSX 3K74A 1DG8A 4X5IA 2XW7A 3SRUX 4ELEA 1SEJA 4XT4A 2AZNA 2ZZAA 1M7AA 3NXVA 1RX1A 3F0XX 2DRCA 5HT5A 1DDRA 1J3KA 1RX6A 4DP3A 3UM5A 3EEMA 2FZIA 4H95A 5JG0X 5HQZA 1PDBA 1RX7A 1ZDRA 1DG7A 1AI9A 3IRMA 1RC4A 4HA7A 4DFRA 5HF0X 2W3BA 3IA5A 4KBNA 4PTJA 3CSEA 3QYLA 1RE7A 3OAFA 3QLXA 4KY4A 4ELHA 3NXOA 4H97A 2HQPA 3RG9A 3SGYA 3SRWX 3JWKA 1BOZA 3EIGA 1DR1A 4P68A 5U26A 1YHOA 4H96A 4KM2A 1MVSA 1RA1A 3FREX 1JUVA 4KD7A 3CL9A 3NZ6X 3N0HA 4P66A 4ELGA 4G3MA 2CIGA 2BLAA 4RGCA 3I8AX 3SR5X 1IA1A 1DRHA 4CD2A 3FYVX 4HOEA 4I1NA 3UM8A 3JTWA 3FQCA 1DHIA 4Q0EA 1RB3A 3LG4A 4OR7A 4EIGA 5CCCA 3NXTA 4XT6A 4EJ1A 4KEBA 4M7VA 3F91A 3INVA 1DR4A 4X5GA 1LUDA 4TU5X 1DAJA 1DYHA 3QYOA 4XT5A 4X5HA 3TQ8A 1PD8A 1J3IA 5HVEA 1PD9A 1RX2A 4M2XA 3IRNA 4M6KA 3K45A 7DFRA 4DPHA 2L28A 5HVBA 1DREA 3UM6A 3FL8A
chains in the Genus database with same CATH topology
3SA2A 3IA4A 2P4GA 1LY4A 3M09A 2W3VA 1KLKA 3TD8A 4QHVA 4PSTA 3QLYA 4FHBA 2W3MA 3KJRA 3IX9A 1RA3A 5EAJA 3VCOA 1HFRA 1CD2A 1S3VA 5DFRA 3TQ9A 4ELBA 4XT8A 4LAGX 3NZBX 3D80A 3S7AA 5E8QA 1S3WA 3JWFA 3DL6A 4HA9A 1S3UA 4KM0A 1M78A 2B3ZA 1DLRA 1J3JA 1RA2A 4IXGX 3OCHA 2D0KA 3TQAA 3RO9A 3QL0A 4M7UA 3QL3A 4H98A 5ECXA 1MVTA 1RX3A 5U27A 2O7PA 3NZ9X 2W9HA 3ZPCA 4KLXA 2HM9A 3I3RA 2INQA 1RA9A 1KMSA 4PTHA 1DLSA 3KFYA 2W9SA 2DHFA 2W3AA 3FQZA 4IXED 5HT4A 2QK8A 3KJSA 3SAIA 3K47A 1RA8A 3TQBA 3F0VX 3QLWA 1RG7A 4XECX 4IXFX 2W9GA 1U70A 1DYIA 3JW3A 1DYJA 3D84X 3NRRA 3FS6A 3DRCA 5JA3A 2JYBA 3NXRA 3F0SX 4LAEX 4PSYA 4NX7A 5HI6A 3FRDX 1DR7A 2BL9A 3NU0A 3F0UX 3FY9X 4QI9A 3S9UA 3GHVA 4FGHA 4QLEA 2H2QA 2W9TA 2KGKA 4PSSA 1RD7A 2D5NA 1IA2A 4DPDA 4FGGA 1U71A 2CD2A 1CZ3A 4XT7A 3S3VA 1DR2A 3JSUA 3GHCA 1DIUA 5HPBA 3FRAX 3QFXA 4KJJA 2ANQA 1DF7A 4QLFA 3SRQX 3FRBX 1JOLA 1RX5A 4XE6X 3KGYA 4P3RA 1DG5A 1OHJA 3CLBA 3FQFA 3NTZA 1DISA 1LY3A 4KY8A 3JWMA 3K2HA 2GD9A 4KFJA 1DHFA 2ANOA 3SRRX 1DDSA 4NX6A 2G6VA 1M79A 1E26A 4QJCA 3ZPGA 1RH3A 4QJZD 3M08A 4LAHX 5HF2X 1HFQA 4DDRA 2ITHA 3DFRA 2W3WA 4KL9A 3NXXA 3FQVA 3L3RA 2FZHA 1RX8A 3QLZA 1OHKA 1JOMA 4Q0DA 3QGTA 1RX9A 3F8YA 3JWCA 1DRBA 1DR6A 1RX4A 3FL9A 2OIPA 2C2TA 2LF1A 1KMVA 3FQOA 1VJ3A 5HQYA 1AOEA 3EEJA 2HXVA 4QLGA 1TDRA 3FY8X 3EELA 3GI2A 1DHJA 3SQYX 3HBBA 5DXVA 5ECCA 3F8ZA 4M6LA 4HOFA 4PDJA 5HSUA 2BLCA 1RB2A 4P3QA 2FZJA 4X5JA 1QZFA 4LEKX 3QLRA 4GH8A 8DFRA 3DG8A 3Q1HA 3EEKA 3F0QX 1DRFA 3HJ3A 1DYRA 3DATA 5HUIA 3KY8A 4ECKA 4KJLA 1AO8A 3FQ0A 3IROA 4KNEA 3DL5A 3F0BX 3FYWX 3JVXA 4X5FA 1RF7A 3QLSA 4Q6AA 3NZCX 1BZFA 4ELFA 4HOGA 4G8ZX 1D1GA 3SH2A 3QG2A 3GYFA 4EIZA 1DR5A 4G95A 3ROAA 6DFRA 1HFPA 3CD2A 1IA4A 3EX8A 5FDAA 4KAKA 1DRAA 3NZAX 3E0BA 3NXYA 1DR3A 1U72A 1S3YA 3NZDA 4XRBA 5CC9A 1VDRA 4I13A 5HSRA 4KYAA 3FRFX 3DGAA 4KJKA 3DAUA 4M6JA 4EILA 3GHWA 2BLBA 3SA1A 2OBCA 1IA3A 2C2SA 3R33A 4Q67A 3JW5A 4OSGA 3SRSX 3K74A 1DG8A 4X5IA 2XW7A 3SRUX 4ELEA 1SEJA 4XT4A 2AZNA 2ZZAA 1M7AA 3NXVA 1RX1A 3F0XX 2DRCA 5HT5A 1DDRA 1J3KA 1RX6A 4DP3A 3UM5A 3EEMA 2FZIA 4H95A 5JG0X 5HQZA 1PDBA 1RX7A 1ZDRA 1DG7A 1AI9A 3IRMA 1RC4A 4HA7A 4DFRA 5HF0X 2W3BA 3IA5A 4KBNA 4PTJA 3CSEA 3QYLA 1RE7A 3OAFA 3QLXA 4KY4A 4ELHA 3NXOA 4H97A 2HQPA 3RG9A 3SGYA 3SRWX 3JWKA 1BOZA 3EIGA 1DR1A 4P68A 5U26A 1YHOA 4H96A 4KM2A 1MVSA 1RA1A 3FREX 1JUVA 4KD7A 3CL9A 3NZ6X 3N0HA 4P66A 4ELGA 4G3MA 2CIGA 2BLAA 4RGCA 3I8AX 3SR5X 1IA1A 1DRHA 4CD2A 3FYVX 4HOEA 4I1NA 3UM8A 3JTWA 3FQCA 1DHIA 4Q0EA 1RB3A 3LG4A 4OR7A 4EIGA 5CCCA 3NXTA 4XT6A 4EJ1A 4KEBA 4M7VA 3F91A 3INVA 1DR4A 4X5GA 1LUDA 4TU5X 1DAJA 1DYHA 3QYOA 4XT5A 4X5HA 3TQ8A 1PD8A 1J3IA 5HVEA 1PD9A 1RX2A 4M2XA 3IRNA 4M6KA 3K45A 7DFRA 4DPHA 2L28A 5HVBA 1DREA 3UM6A 3FL8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SA2 A;  3IA4 A;  2P4G A;  1LY4 A;  3M09 A;  2W3V A;  1KLK A;  3TD8 A;  4QHV A;  4PST A;  3QLY A;  4FHB A;  2W3M A;  3KJR A;  3IX9 A;  1RA3 A;  5EAJ A;  3VCO A;  1HFR A;  1CD2 A;  1S3V A;  5DFR A;  3TQ9 A;  4ELB A;  4XT8 A;  4LAG X;  3NZB X;  3D80 A;  3S7A A;  5E8Q A;  1S3W A;  3JWF A;  3DL6 A;  4HA9 A;  1S3U A;  4KM0 A;  1M78 A;  2B3Z A;  1DLR A;  1J3J A;  1RA2 A;  4IXG X;  3OCH A;  2D0K A;  3TQA A;  3RO9 A;  3QL0 A;  4M7U A;  3QL3 A;  4H98 A;  5ECX A;  1MVT A;  1RX3 A;  5U27 A;  2O7P A;  3NZ9 X;  2W9H A;  3ZPC A;  4KLX A;  2HM9 A;  3I3R A;  2INQ A;  1RA9 A;  1KMS A;  4PTH A;  1DLS A;  3KFY A;  2W9S A;  2DHF A;  2W3A A;  3FQZ A;  4IXE D;  5HT4 A;  2QK8 A;  3KJS A;  3SAI A;  3K47 A;  1RA8 A;  3TQB A;  3F0V X;  3QLW A;  1RG7 A;  4XEC X;  4IXF X;  2W9G A;  1U70 A;  1DYI A;  3JW3 A;  1DYJ A;  3D84 X;  3NRR A;  3FS6 A;  3DRC A;  5JA3 A;  2JYB A;  3NXR A;  3F0S X;  4LAE X;  4PSY A;  4NX7 A;  5HI6 A;  3FRD X;  1DR7 A;  2BL9 A;  3NU0 A;  3F0U X;  3FY9 X;  4QI9 A;  3S9U A;  3GHV A;  4FGH A;  4QLE A;  2H2Q A;  2W9T A;  2KGK A;  4PSS A;  1RD7 A;  2D5N A;  1IA2 A;  4DPD A;  4FGG A;  1U71 A;  2CD2 A;  1CZ3 A;  4XT7 A;  3S3V A;  1DR2 A;  3JSU A;  3GHC A;  1DIU A;  5HPB A;  3FRA X;  3QFX A;  4KJJ A;  2ANQ A;  1DF7 A;  4QLF A;  3SRQ X;  3FRB X;  1JOL A;  1RX5 A;  4XE6 X;  3KGY A;  4P3R A;  1DG5 A;  1OHJ A;  3CLB A;  3FQF A;  3NTZ A;  1DIS A;  1LY3 A;  4KY8 A;  3JWM A;  3K2H A;  2GD9 A;  4KFJ A;  1DHF A;  2ANO A;  3SRR X;  1DDS A;  4NX6 A;  2G6V A;  1M79 A;  1E26 A;  4QJC A;  3ZPG A;  1RH3 A;  4QJZ D;  3M08 A;  4LAH X;  5HF2 X;  1HFQ A;  4DDR A;  2ITH A;  3DFR A;  2W3W A;  4KL9 A;  3NXX A;  3FQV A;  3L3R A;  2FZH A;  1RX8 A;  3QLZ A;  1OHK A;  1JOM A;  4Q0D A;  3QGT A;  1RX9 A;  3F8Y A;  3JWC A;  1DRB A;  1DR6 A;  1RX4 A;  3FL9 A;  2OIP A;  2C2T A;  2LF1 A;  1KMV A;  3FQO A;  1VJ3 A;  5HQY A;  1AOE A;  3EEJ A;  2HXV A;  4QLG A;  1TDR A;  3FY8 X;  3EEL A;  3GI2 A;  1DHJ A;  3SQY X;  3HBB A;  5DXV A;  5ECC A;  3F8Z A;  4M6L A;  4HOF A;  4PDJ A;  5HSU A;  2BLC A;  1RB2 A;  4P3Q A;  2FZJ A;  4X5J A;  1QZF A;  4LEK X;  3QLR A;  4GH8 A;  8DFR A;  3DG8 A;  3Q1H A;  3EEK A;  3F0Q X;  1DRF A;  3HJ3 A;  1DYR A;  3DAT A;  5HUI A;  3KY8 A;  4ECK A;  4KJL A;  1AO8 A;  3FQ0 A;  3IRO A;  4KNE A;  3DL5 A;  3F0B X;  3FYW X;  3JVX A;  4X5F A;  1RF7 A;  3QLS A;  4Q6A A;  3NZC X;  1BZF A;  4ELF A;  4HOG A;  4G8Z X;  1D1G A;  3SH2 A;  3QG2 A;  3GYF A;  4EIZ A;  1DR5 A;  4G95 A;  3ROA A;  6DFR A;  1HFP A;  3CD2 A;  1IA4 A;  3EX8 A;  5FDA A;  4KAK A;  1DRA A;  3NZA X;  3E0B A;  3NXY A;  1DR3 A;  1U72 A;  1S3Y A;  3NZD A;  4XRB A;  5CC9 A;  1VDR A;  4I13 A;  5HSR A;  4KYA A;  3FRF X;  3DGA A;  4KJK A;  3DAU A;  4M6J A;  4EIL A;  3GHW A;  2BLB A;  3SA1 A;  2OBC A;  1IA3 A;  2C2S A;  3R33 A;  4Q67 A;  3JW5 A;  4OSG A;  3SRS X;  3K74 A;  1DG8 A;  4X5I A;  2XW7 A;  3SRU X;  4ELE A;  1SEJ A;  4XT4 A;  2AZN A;  2ZZA A;  1M7A A;  3NXV A;  1RX1 A;  3F0X X;  2DRC A;  5HT5 A;  1DDR A;  1J3K A;  1RX6 A;  4DP3 A;  3UM5 A;  3EEM A;  2FZI A;  4H95 A;  5JG0 X;  5HQZ A;  1PDB A;  1RX7 A;  1ZDR A;  1DG7 A;  1AI9 A;  3IRM A;  1RC4 A;  4HA7 A;  4DFR A;  5HF0 X;  2W3B A;  3IA5 A;  4KBN A;  4PTJ A;  3CSE A;  3QYL A;  1RE7 A;  3OAF A;  3QLX A;  4KY4 A;  4ELH A;  3NXO A;  4H97 A;  2HQP A;  3RG9 A;  3SGY A;  3SRW X;  3JWK A;  1BOZ A;  3EIG A;  1DR1 A;  4P68 A;  5U26 A;  1YHO A;  4H96 A;  4KM2 A;  1MVS A;  1RA1 A;  3FRE X;  1JUV A;  4KD7 A;  3CL9 A;  3NZ6 X;  3N0H A;  4P66 A;  4ELG A;  4G3M A;  2CIG A;  2BLA A;  4RGC A;  3I8A X;  3SR5 X;  1IA1 A;  1DRH A;  4CD2 A;  3FYV X;  4HOE A;  4I1N A;  3UM8 A;  3JTW A;  3FQC A;  1DHI A;  4Q0E A;  1RB3 A;  3LG4 A;  4OR7 A;  4EIG A;  5CCC A;  3NXT A;  4XT6 A;  4EJ1 A;  4KEB A;  4M7V A;  3F91 A;  3INV A;  1DR4 A;  4X5G A;  1LUD A;  4TU5 X;  1DAJ A;  1DYH A;  3QYO A;  4XT5 A;  4X5H A;  3TQ8 A;  1PD8 A;  1J3I A;  5HVE A;  1PD9 A;  1RX2 A;  4M2X A;  3IRN A;  4M6K A;  3K45 A;  7DFR A;  4DPH A;  2L28 A;  5HVB A;  1DRE A;  3UM6 A;  3FL8 A; 
#chains in the Genus database with same CATH topology
 3SA2 A;  3IA4 A;  2P4G A;  1LY4 A;  3M09 A;  2W3V A;  1KLK A;  3TD8 A;  4QHV A;  4PST A;  3QLY A;  4FHB A;  2W3M A;  3KJR A;  3IX9 A;  1RA3 A;  5EAJ A;  3VCO A;  1HFR A;  1CD2 A;  1S3V A;  5DFR A;  3TQ9 A;  4ELB A;  4XT8 A;  4LAG X;  3NZB X;  3D80 A;  3S7A A;  5E8Q A;  1S3W A;  3JWF A;  3DL6 A;  4HA9 A;  1S3U A;  4KM0 A;  1M78 A;  2B3Z A;  1DLR A;  1J3J A;  1RA2 A;  4IXG X;  3OCH A;  2D0K A;  3TQA A;  3RO9 A;  3QL0 A;  4M7U A;  3QL3 A;  4H98 A;  5ECX A;  1MVT A;  1RX3 A;  5U27 A;  2O7P A;  3NZ9 X;  2W9H A;  3ZPC A;  4KLX A;  2HM9 A;  3I3R A;  2INQ A;  1RA9 A;  1KMS A;  4PTH A;  1DLS A;  3KFY A;  2W9S A;  2DHF A;  2W3A A;  3FQZ A;  4IXE D;  5HT4 A;  2QK8 A;  3KJS A;  3SAI A;  3K47 A;  1RA8 A;  3TQB A;  3F0V X;  3QLW A;  1RG7 A;  4XEC X;  4IXF X;  2W9G A;  1U70 A;  1DYI A;  3JW3 A;  1DYJ A;  3D84 X;  3NRR A;  3FS6 A;  3DRC A;  5JA3 A;  2JYB A;  3NXR A;  3F0S X;  4LAE X;  4PSY A;  4NX7 A;  5HI6 A;  3FRD X;  1DR7 A;  2BL9 A;  3NU0 A;  3F0U X;  3FY9 X;  4QI9 A;  3S9U A;  3GHV A;  4FGH A;  4QLE A;  2H2Q A;  2W9T A;  2KGK A;  4PSS A;  1RD7 A;  2D5N A;  1IA2 A;  4DPD A;  4FGG A;  1U71 A;  2CD2 A;  1CZ3 A;  4XT7 A;  3S3V A;  1DR2 A;  3JSU A;  3GHC A;  1DIU A;  5HPB A;  3FRA X;  3QFX A;  4KJJ A;  2ANQ A;  1DF7 A;  4QLF A;  3SRQ X;  3FRB X;  1JOL A;  1RX5 A;  4XE6 X;  3KGY A;  4P3R A;  1DG5 A;  1OHJ A;  3CLB A;  3FQF A;  3NTZ A;  1DIS A;  1LY3 A;  4KY8 A;  3JWM A;  3K2H A;  2GD9 A;  4KFJ A;  1DHF A;  2ANO A;  3SRR X;  1DDS A;  4NX6 A;  2G6V A;  1M79 A;  1E26 A;  4QJC A;  3ZPG A;  1RH3 A;  4QJZ D;  3M08 A;  4LAH X;  5HF2 X;  1HFQ A;  4DDR A;  2ITH A;  3DFR A;  2W3W A;  4KL9 A;  3NXX A;  3FQV A;  3L3R A;  2FZH A;  1RX8 A;  3QLZ A;  1OHK A;  1JOM A;  4Q0D A;  3QGT A;  1RX9 A;  3F8Y A;  3JWC A;  1DRB A;  1DR6 A;  1RX4 A;  3FL9 A;  2OIP A;  2C2T A;  2LF1 A;  1KMV A;  3FQO A;  1VJ3 A;  5HQY A;  1AOE A;  3EEJ A;  2HXV A;  4QLG A;  1TDR A;  3FY8 X;  3EEL A;  3GI2 A;  1DHJ A;  3SQY X;  3HBB A;  5DXV A;  5ECC A;  3F8Z A;  4M6L A;  4HOF A;  4PDJ A;  5HSU A;  2BLC A;  1RB2 A;  4P3Q A;  2FZJ A;  4X5J A;  1QZF A;  4LEK X;  3QLR A;  4GH8 A;  8DFR A;  3DG8 A;  3Q1H A;  3EEK A;  3F0Q X;  1DRF A;  3HJ3 A;  1DYR A;  3DAT A;  5HUI A;  3KY8 A;  4ECK A;  4KJL A;  1AO8 A;  3FQ0 A;  3IRO A;  4KNE A;  3DL5 A;  3F0B X;  3FYW X;  3JVX A;  4X5F A;  1RF7 A;  3QLS A;  4Q6A A;  3NZC X;  1BZF A;  4ELF A;  4HOG A;  4G8Z X;  1D1G A;  3SH2 A;  3QG2 A;  3GYF A;  4EIZ A;  1DR5 A;  4G95 A;  3ROA A;  6DFR A;  1HFP A;  3CD2 A;  1IA4 A;  3EX8 A;  5FDA A;  4KAK A;  1DRA A;  3NZA X;  3E0B A;  3NXY A;  1DR3 A;  1U72 A;  1S3Y A;  3NZD A;  4XRB A;  5CC9 A;  1VDR A;  4I13 A;  5HSR A;  4KYA A;  3FRF X;  3DGA A;  4KJK A;  3DAU A;  4M6J A;  4EIL A;  3GHW A;  2BLB A;  3SA1 A;  2OBC A;  1IA3 A;  2C2S A;  3R33 A;  4Q67 A;  3JW5 A;  4OSG A;  3SRS X;  3K74 A;  1DG8 A;  4X5I A;  2XW7 A;  3SRU X;  4ELE A;  1SEJ A;  4XT4 A;  2AZN A;  2ZZA A;  1M7A A;  3NXV A;  1RX1 A;  3F0X X;  2DRC A;  5HT5 A;  1DDR A;  1J3K A;  1RX6 A;  4DP3 A;  3UM5 A;  3EEM A;  2FZI A;  4H95 A;  5JG0 X;  5HQZ A;  1PDB A;  1RX7 A;  1ZDR A;  1DG7 A;  1AI9 A;  3IRM A;  1RC4 A;  4HA7 A;  4DFR A;  5HF0 X;  2W3B A;  3IA5 A;  4KBN A;  4PTJ A;  3CSE A;  3QYL A;  1RE7 A;  3OAF A;  3QLX A;  4KY4 A;  4ELH A;  3NXO A;  4H97 A;  2HQP A;  3RG9 A;  3SGY A;  3SRW X;  3JWK A;  1BOZ A;  3EIG A;  1DR1 A;  4P68 A;  5U26 A;  1YHO A;  4H96 A;  4KM2 A;  1MVS A;  1RA1 A;  3FRE X;  1JUV A;  4KD7 A;  3CL9 A;  3NZ6 X;  3N0H A;  4P66 A;  4ELG A;  4G3M A;  2CIG A;  2BLA A;  4RGC A;  3I8A X;  3SR5 X;  1IA1 A;  1DRH A;  4CD2 A;  3FYV X;  4HOE A;  4I1N A;  3UM8 A;  3JTW A;  3FQC A;  1DHI A;  4Q0E A;  1RB3 A;  3LG4 A;  4OR7 A;  4EIG A;  5CCC A;  3NXT A;  4XT6 A;  4EJ1 A;  4KEB A;  4M7V A;  3F91 A;  3INV A;  1DR4 A;  4X5G A;  1LUD A;  4TU5 X;  1DAJ A;  1DYH A;  3QYO A;  4XT5 A;  4X5H A;  3TQ8 A;  1PD8 A;  1J3I A;  5HVE A;  1PD9 A;  1RX2 A;  4M2X A;  3IRN A;  4M6K A;  3K45 A;  7DFR A;  4DPH A;  2L28 A;  5HVB A;  1DRE A;  3UM6 A;  3FL8 A; 
#chains in the Genus database with same CATH homology
 3SA2 A;  3IA4 A;  2P4G A;  1LY4 A;  3M09 A;  2W3V A;  1KLK A;  3TD8 A;  4QHV A;  4PST A;  3QLY A;  4FHB A;  2W3M A;  3KJR A;  3IX9 A;  1RA3 A;  5EAJ A;  3VCO A;  1HFR A;  1CD2 A;  1S3V A;  5DFR A;  3TQ9 A;  4ELB A;  4XT8 A;  4LAG X;  3NZB X;  3D80 A;  3S7A A;  5E8Q A;  1S3W A;  3JWF A;  3DL6 A;  4HA9 A;  1S3U A;  4KM0 A;  1M78 A;  2B3Z A;  1DLR A;  1J3J A;  1RA2 A;  4IXG X;  3OCH A;  2D0K A;  3TQA A;  3RO9 A;  3QL0 A;  4M7U A;  3QL3 A;  4H98 A;  5ECX A;  1MVT A;  1RX3 A;  5U27 A;  2O7P A;  3NZ9 X;  2W9H A;  3ZPC A;  4KLX A;  2HM9 A;  3I3R A;  2INQ A;  1RA9 A;  1KMS A;  4PTH A;  1DLS A;  3KFY A;  2W9S A;  2DHF A;  2W3A A;  3FQZ A;  4IXE D;  5HT4 A;  2QK8 A;  3KJS A;  3SAI A;  3K47 A;  1RA8 A;  3TQB A;  3F0V X;  3QLW A;  1RG7 A;  4XEC X;  4IXF X;  2W9G A;  1U70 A;  1DYI A;  3JW3 A;  1DYJ A;  3D84 X;  3NRR A;  3FS6 A;  3DRC A;  5JA3 A;  2JYB A;  3NXR A;  3F0S X;  4LAE X;  4PSY A;  4NX7 A;  5HI6 A;  3FRD X;  1DR7 A;  2BL9 A;  3NU0 A;  3F0U X;  3FY9 X;  4QI9 A;  3S9U A;  3GHV A;  4FGH A;  4QLE A;  2H2Q A;  2W9T A;  2KGK A;  4PSS A;  1RD7 A;  2D5N A;  1IA2 A;  4DPD A;  4FGG A;  1U71 A;  2CD2 A;  1CZ3 A;  4XT7 A;  3S3V A;  1DR2 A;  3JSU A;  3GHC A;  1DIU A;  5HPB A;  3FRA X;  3QFX A;  4KJJ A;  2ANQ A;  1DF7 A;  4QLF A;  3SRQ X;  3FRB X;  1JOL A;  1RX5 A;  4XE6 X;  3KGY A;  4P3R A;  1DG5 A;  1OHJ A;  3CLB A;  3FQF A;  3NTZ A;  1DIS A;  1LY3 A;  4KY8 A;  3JWM A;  3K2H A;  2GD9 A;  4KFJ A;  1DHF A;  2ANO A;  3SRR X;  1DDS A;  4NX6 A;  2G6V A;  1M79 A;  1E26 A;  4QJC A;  3ZPG A;  1RH3 A;  4QJZ D;  3M08 A;  4LAH X;  5HF2 X;  1HFQ A;  4DDR A;  2ITH A;  3DFR A;  2W3W A;  4KL9 A;  3NXX A;  3FQV A;  3L3R A;  2FZH A;  1RX8 A;  3QLZ A;  1OHK A;  1JOM A;  4Q0D A;  3QGT A;  1RX9 A;  3F8Y A;  3JWC A;  1DRB A;  1DR6 A;  1RX4 A;  3FL9 A;  2OIP A;  2C2T A;  2LF1 A;  1KMV A;  3FQO A;  1VJ3 A;  5HQY A;  1AOE A;  3EEJ A;  2HXV A;  4QLG A;  1TDR A;  3FY8 X;  3EEL A;  3GI2 A;  1DHJ A;  3SQY X;  3HBB A;  5DXV A;  5ECC A;  3F8Z A;  4M6L A;  4HOF A;  4PDJ A;  5HSU A;  2BLC A;  1RB2 A;  4P3Q A;  2FZJ A;  4X5J A;  1QZF A;  4LEK X;  3QLR A;  4GH8 A;  8DFR A;  3DG8 A;  3Q1H A;  3EEK A;  3F0Q X;  1DRF A;  3HJ3 A;  1DYR A;  3DAT A;  5HUI A;  3KY8 A;  4ECK A;  4KJL A;  1AO8 A;  3FQ0 A;  3IRO A;  4KNE A;  3DL5 A;  3F0B X;  3FYW X;  3JVX A;  4X5F A;  1RF7 A;  3QLS A;  4Q6A A;  3NZC X;  1BZF A;  4ELF A;  4HOG A;  4G8Z X;  1D1G A;  3SH2 A;  3QG2 A;  3GYF A;  4EIZ A;  1DR5 A;  4G95 A;  3ROA A;  6DFR A;  1HFP A;  3CD2 A;  1IA4 A;  3EX8 A;  5FDA A;  4KAK A;  1DRA A;  3NZA X;  3E0B A;  3NXY A;  1DR3 A;  1U72 A;  1S3Y A;  3NZD A;  4XRB A;  5CC9 A;  1VDR A;  4I13 A;  5HSR A;  4KYA A;  3FRF X;  3DGA A;  4KJK A;  3DAU A;  4M6J A;  4EIL A;  3GHW A;  2BLB A;  3SA1 A;  2OBC A;  1IA3 A;  2C2S A;  3R33 A;  4Q67 A;  3JW5 A;  4OSG A;  3SRS X;  3K74 A;  1DG8 A;  4X5I A;  2XW7 A;  3SRU X;  4ELE A;  1SEJ A;  4XT4 A;  2AZN A;  2ZZA A;  1M7A A;  3NXV A;  1RX1 A;  3F0X X;  2DRC A;  5HT5 A;  1DDR A;  1J3K A;  1RX6 A;  4DP3 A;  3UM5 A;  3EEM A;  2FZI A;  4H95 A;  5JG0 X;  5HQZ A;  1PDB A;  1RX7 A;  1ZDR A;  1DG7 A;  1AI9 A;  3IRM A;  1RC4 A;  4HA7 A;  4DFR A;  5HF0 X;  2W3B A;  3IA5 A;  4KBN A;  4PTJ A;  3CSE A;  3QYL A;  1RE7 A;  3OAF A;  3QLX A;  4KY4 A;  4ELH A;  3NXO A;  4H97 A;  2HQP A;  3RG9 A;  3SGY A;  3SRW X;  3JWK A;  1BOZ A;  3EIG A;  1DR1 A;  4P68 A;  5U26 A;  1YHO A;  4H96 A;  4KM2 A;  1MVS A;  1RA1 A;  3FRE X;  1JUV A;  4KD7 A;  3CL9 A;  3NZ6 X;  3N0H A;  4P66 A;  4ELG A;  4G3M A;  2CIG A;  2BLA A;  4RGC A;  3I8A X;  3SR5 X;  1IA1 A;  1DRH A;  4CD2 A;  3FYV X;  4HOE A;  4I1N A;  3UM8 A;  3JTW A;  3FQC A;  1DHI A;  4Q0E A;  1RB3 A;  3LG4 A;  4OR7 A;  4EIG A;  5CCC A;  3NXT A;  4XT6 A;  4EJ1 A;  4KEB A;  4M7V A;  3F91 A;  3INV A;  1DR4 A;  4X5G A;  1LUD A;  4TU5 X;  1DAJ A;  1DYH A;  3QYO A;  4XT5 A;  4X5H A;  3TQ8 A;  1PD8 A;  1J3I A;  5HVE A;  1PD9 A;  1RX2 A;  4M2X A;  3IRN A;  4M6K A;  3K45 A;  7DFR A;  4DPH A;  2L28 A;  5HVB A;  1DRE A;  3UM6 A;  3FL8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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