5ECXA

Klebsiella pneumoniae dfra1 complexed with nadph and 6-ethyl-5-(3-(6-(pyridin-4-yl)benzo[d][1,3]dioxol-4-yl)but-1-yn-1-yl)pyrimidine-2,4-diamine
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
157
structure length
157
Chain Sequence
MKLSLMVAISKNGVIGNGPDIPWSAKGEQLLFKAITYNQWLLVGRKTFESMGALPNRKYAVVTRSSFTSDNENVLIFPSIKDALTNLKKITDHVIVSGGGEIYKSLIDQVDTLHISTIDIEPEGDVYFPEIPSNFRPVFTQDFASNINYSYQIWQKG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Trimethoprim-Resistant DfrA1 Rationalize Potent Inhibition by Propargyl-Linked Antifolates.
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Klebsiella pneumoniae
molecule keywords Dehydrofolate reductase type I
total genus 47
structure length 157
sequence length 157
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-10-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 5ecxA00
4NX6A 3FQ0A 1DF7A 5HPBA 1RB3A 3SRUX 4KJLA 3TQ9A 3KJSA 2FZJA 2BLCA 3NXOA 1DYRA 1LY4A 4QLEA 3QG2A 3E0BA 3SRRX 1J3IA 2W9SA 3FY9X 1VJ3A 2W3BA 4LAGX 3F0QX 3F0BX 3FREX 4HA9A 1BZFA 3CLBA 5E8QA 1M79A 3HBBA 1LY3A 3INVA 1RX2A 3FY8X 3I8AX 1JOMA 3GHVA 4FGGA 3FL8A 3FRAX 3EEMA 3ROAA 1DG8A 1U72A 3DATA 3F8YA 3GHCA 6DFRA 2W9GA 3DRCA 1RA2A 3FQFA 1OHKA 3KJRA 3IROA 4LAHX 1QZFA 2BL9A 1KMVA 4G8ZX 4KM2A 4H96A 4M2XA 1S3WA 3K47A 3S3VA 2P4GA 2G6VA 2OIPA 2HM9A 4KD7A 1AI9A 3SRSX 3F0XX 3FYWX 3DL5A 3JW5A 4DPHA 3K74A 4P3QA 4M6LA 4XECX 7DFRA 2D0KA 4X5FA 2C2TA 1RX7A 4CD2A 1RC4A 1DG5A 1DISA 2C2SA 1HFRA 1HFQA 1RH3A 1RX6A 3NU0A 1MVSA 2HQPA 3LG4A 2CIGA 3SR5X 3GI2A 5HUIA 1IA4A 4I13A 3QL0A 1RA3A 4KM0A 3FL9A 3UM5A 3KY8A 1DLSA 3D84X 5HSRA 3JWCA 4KJJA 4OR7A 5HQZA 4FGHA 3FQCA 1RE7A 4DFRA 3D80A 3TQ8A 1PDBA 3QLRA 3F0SX 4OSGA 1SEJA 3FRFX 1KLKA 2AZNA 1IA1A 2ITHA 3IA4A 1MVTA 4QJCA 2ZZAA 1D1GA 3M09A 1DR5A 3SAIA 1PD9A 2H2QA 3IRMA 3RO9A 4ECKA 1RG7A 4KY8A 3Q1HA 4M7VA 1LUDA 1M7AA 1JUVA 3JWFA 3EIGA 4KNEA 5CCCA 2KGKA 3UM6A 1S3YA 3CSEA 3FRBX 1RD7A 4H97A 4PSTA 3IRNA 1DR6A 5EAJA 1DLRA 1DG7A 1DHFA 1DREA 2W3MA 3QLZA 2BLBA 2ANQA 3QGTA 4IXFX 4IXED 2CD2A 1U71A 5HI6A 3FQVA 4XT6A 4HA7A 3GHWA 3EEKA 4IXGX 3FQOA 1DR3A 3QLWA 3FQZA 4P66A 3RG9A 4QHVA 3DAUA 4H95A 3FS6A 5CC9A 3SGYA 4DDRA 3EX8A 3NXYA 4P3RA 1M78A 4KL9A 4PSSA 5HF2X 1ZDRA 8DFRA 4Q67A 3NRRA 2OBCA 5HVEA 5DXVA 3QLSA 1U70A 4FHBA 4LEKX 3TD8A 5HSUA 3F91A 3NXRA 3SA1A 1VDRA 3F8ZA 4Q0EA 1KMSA 1RA9A 1CZ3A 5ECXA 3UM8A 4M6JA 3NXVA 1BOZA 5JA3A 4G95A 4Q0DA 1DR4A 3IA5A 1AO8A 5FDAA 3DL6A 5HF0X 3FRDX 4DP3A 2XW7A 3JVXA 3S9UA 2FZIA 3I3RA 3SRQX 1DR2A 1HFPA 4KLXA 4X5HA 4ELFA 1DYHA 4KAKA 1S3UA 3F0UX 3OAFA 2QK8A 4KFJA 4PTJA 3ZPCA 5HQYA 3NZDA 1CD2A 1IA3A 1DRHA 4I1NA 3NZAX 4H98A 3QL3A 3NTZA 1RX3A 1E26A 3QLXA 3N0HA 5ECCA 1DYIA 3TQAA 1DDSA 1OHJA 4XT7A 5U27A 4XT5A 4KY4A 3FYVX 3KFYA 4X5IA 3JTWA 3IX9A 2W3VA 4G3MA 3SA2A 1DRBA 4PDJA 4HOEA 1J3JA 4EJ1A 2D5NA 3L3RA 1DR7A 1AOEA 2B3ZA 3NZCX 1DR1A 3SH2A 1RF7A 4GH8A 3S7AA 2DHFA 2BLAA 2L28A 4M6KA 1TDRA 3NZ9X 4XT8A 2W9HA 4QJZD 3SRWX 3QFXA 4P68A 2INQA 4RGCA 1RX1A 2FZHA 4KYAA 3JWMA 1DHIA 1DDRA 1RX4A 2JYBA 1DHJA 1RX5A 3K2HA 3JW3A 4DPDA 3DGAA 5U26A 4QLGA 3JSUA 4M7UA 4LAEX 3NXXA 5HVBA 2O7PA 3QYLA 1IA2A 1YHOA 2ANOA 4NX7A 3CL9A 2W9TA 4KBNA 4XE6X 2W3AA 3CD2A 3M08A 3QLYA 2DRCA 3NZBX 3OCHA 4KEBA 3GYFA 2W3WA 4X5JA 4XRBA 4ELGA 4ELEA 2HXVA 1PD8A 4Q6AA 4QLFA 3TQBA 3DFRA 3DG8A 2GD9A 1J3KA 3EEJA 1S3VA 1RX8A 4X5GA 3NZ6X 5HT5A 1RB2A 1JOLA 4HOFA 1DIUA 4PSYA 1DRAA 1RX9A 3K45A 4PTHA 3QYOA 4KJKA 3ZPGA 4ELBA 5HT4A 4TU5X 5JG0X 4XT4A 3NXTA 1DRFA 4EIZA 1DAJA 2LF1A 3SQYX 4EIGA 5DFRA 4ELHA 1DYJA 3HJ3A 3EELA 1RA8A 3R33A 3VCOA 3KGYA 3JWKA 4EILA 3F0VX 1RA1A 4HOGA 4QI9A
chains in the Genus database with same CATH superfamily
4NX6A 3FQ0A 1DF7A 5HPBA 1RB3A 3SRUX 4KJLA 3TQ9A 3KJSA 2FZJA 2BLCA 3NXOA 1DYRA 1LY4A 4QLEA 3QG2A 3E0BA 3SRRX 1J3IA 2W9SA 3FY9X 1VJ3A 2W3BA 4LAGX 3F0QX 3F0BX 3FREX 4HA9A 1BZFA 3CLBA 5E8QA 1M79A 3HBBA 1LY3A 3INVA 1RX2A 3FY8X 3I8AX 1JOMA 3GHVA 4FGGA 3FL8A 3FRAX 3EEMA 3ROAA 1DG8A 1U72A 3DATA 3F8YA 3GHCA 6DFRA 2W9GA 3DRCA 1RA2A 3FQFA 1OHKA 3KJRA 3IROA 4LAHX 1QZFA 2BL9A 1KMVA 4G8ZX 4KM2A 4H96A 4M2XA 1S3WA 3K47A 3S3VA 2P4GA 2G6VA 2OIPA 2HM9A 4KD7A 1AI9A 3SRSX 3F0XX 3FYWX 3DL5A 3JW5A 4DPHA 3K74A 4P3QA 4M6LA 4XECX 7DFRA 2D0KA 4X5FA 2C2TA 1RX7A 4CD2A 1RC4A 1DG5A 1DISA 2C2SA 1HFRA 1HFQA 1RH3A 1RX6A 3NU0A 1MVSA 2HQPA 3LG4A 2CIGA 3SR5X 3GI2A 5HUIA 1IA4A 4I13A 3QL0A 1RA3A 4KM0A 3FL9A 3UM5A 3KY8A 1DLSA 3D84X 5HSRA 3JWCA 4KJJA 4OR7A 5HQZA 4FGHA 3FQCA 1RE7A 4DFRA 3D80A 3TQ8A 1PDBA 3QLRA 3F0SX 4OSGA 1SEJA 3FRFX 1KLKA 2AZNA 1IA1A 2ITHA 3IA4A 1MVTA 4QJCA 2ZZAA 1D1GA 3M09A 1DR5A 3SAIA 1PD9A 2H2QA 3IRMA 3RO9A 4ECKA 1RG7A 4KY8A 3Q1HA 4M7VA 1LUDA 1M7AA 1JUVA 3JWFA 3EIGA 4KNEA 5CCCA 2KGKA 3UM6A 1S3YA 3CSEA 3FRBX 1RD7A 4H97A 4PSTA 3IRNA 1DR6A 5EAJA 1DLRA 1DG7A 1DHFA 1DREA 2W3MA 3QLZA 2BLBA 2ANQA 3QGTA 4IXFX 4IXED 2CD2A 1U71A 5HI6A 3FQVA 4XT6A 4HA7A 3GHWA 3EEKA 4IXGX 3FQOA 1DR3A 3QLWA 3FQZA 4P66A 3RG9A 4QHVA 3DAUA 4H95A 3FS6A 5CC9A 3SGYA 4DDRA 3EX8A 3NXYA 4P3RA 1M78A 4KL9A 4PSSA 5HF2X 1ZDRA 8DFRA 4Q67A 3NRRA 2OBCA 5HVEA 5DXVA 3QLSA 1U70A 4FHBA 4LEKX 3TD8A 5HSUA 3F91A 3NXRA 3SA1A 1VDRA 3F8ZA 4Q0EA 1KMSA 1RA9A 1CZ3A 5ECXA 3UM8A 4M6JA 3NXVA 1BOZA 5JA3A 4G95A 4Q0DA 1DR4A 3IA5A 1AO8A 5FDAA 3DL6A 5HF0X 3FRDX 4DP3A 2XW7A 3JVXA 3S9UA 2FZIA 3I3RA 3SRQX 1DR2A 1HFPA 4KLXA 4X5HA 4ELFA 1DYHA 4KAKA 1S3UA 3F0UX 3OAFA 2QK8A 4KFJA 4PTJA 3ZPCA 5HQYA 3NZDA 1CD2A 1IA3A 1DRHA 4I1NA 3NZAX 4H98A 3QL3A 3NTZA 1RX3A 1E26A 3QLXA 3N0HA 5ECCA 1DYIA 3TQAA 1DDSA 1OHJA 4XT7A 5U27A 4XT5A 4KY4A 3FYVX 3KFYA 4X5IA 3JTWA 3IX9A 2W3VA 4G3MA 3SA2A 1DRBA 4PDJA 4HOEA 1J3JA 4EJ1A 2D5NA 3L3RA 1DR7A 1AOEA 2B3ZA 3NZCX 1DR1A 3SH2A 1RF7A 4GH8A 3S7AA 2DHFA 2BLAA 2L28A 4M6KA 1TDRA 3NZ9X 4XT8A 2W9HA 4QJZD 3SRWX 3QFXA 4P68A 2INQA 4RGCA 1RX1A 2FZHA 4KYAA 3JWMA 1DHIA 1DDRA 1RX4A 2JYBA 1DHJA 1RX5A 3K2HA 3JW3A 4DPDA 3DGAA 5U26A 4QLGA 3JSUA 4M7UA 4LAEX 3NXXA 5HVBA 2O7PA 3QYLA 1IA2A 1YHOA 2ANOA 4NX7A 3CL9A 2W9TA 4KBNA 4XE6X 2W3AA 3CD2A 3M08A 3QLYA 2DRCA 3NZBX 3OCHA 4KEBA 3GYFA 2W3WA 4X5JA 4XRBA 4ELGA 4ELEA 2HXVA 1PD8A 4Q6AA 4QLFA 3TQBA 3DFRA 3DG8A 2GD9A 1J3KA 3EEJA 1S3VA 1RX8A 4X5GA 3NZ6X 5HT5A 1RB2A 1JOLA 4HOFA 1DIUA 4PSYA 1DRAA 1RX9A 3K45A 4PTHA 3QYOA 4KJKA 3ZPGA 4ELBA 5HT4A 4TU5X 5JG0X 4XT4A 3NXTA 1DRFA 4EIZA 1DAJA 2LF1A 3SQYX 4EIGA 5DFRA 4ELHA 1DYJA 3HJ3A 3EELA 1RA8A 3R33A 3VCOA 3KGYA 3JWKA 4EILA 3F0VX 1RA1A 4HOGA 4QI9A
chains in the Genus database with same CATH topology
4NX6A 3FQ0A 1DF7A 5HPBA 1RB3A 3SRUX 4KJLA 3TQ9A 3KJSA 2FZJA 2BLCA 3NXOA 1DYRA 1LY4A 4QLEA 3QG2A 3E0BA 3SRRX 1J3IA 2W9SA 3FY9X 1VJ3A 2W3BA 4LAGX 3F0QX 3F0BX 3FREX 4HA9A 1BZFA 3CLBA 5E8QA 1M79A 3HBBA 1LY3A 3INVA 1RX2A 3FY8X 3I8AX 1JOMA 3GHVA 4FGGA 3FL8A 3FRAX 3EEMA 3ROAA 1DG8A 1U72A 3DATA 3F8YA 3GHCA 6DFRA 2W9GA 3DRCA 1RA2A 3FQFA 1OHKA 3KJRA 3IROA 4LAHX 1QZFA 2BL9A 1KMVA 4G8ZX 4KM2A 4H96A 4M2XA 1S3WA 3K47A 3S3VA 2P4GA 2G6VA 2OIPA 2HM9A 4KD7A 1AI9A 3SRSX 3F0XX 3FYWX 3DL5A 3JW5A 4DPHA 3K74A 4P3QA 4M6LA 4XECX 7DFRA 2D0KA 4X5FA 2C2TA 1RX7A 4CD2A 1RC4A 1DG5A 1DISA 2C2SA 1HFRA 1HFQA 1RH3A 1RX6A 3NU0A 1MVSA 2HQPA 3LG4A 2CIGA 3SR5X 3GI2A 5HUIA 1IA4A 4I13A 3QL0A 1RA3A 4KM0A 3FL9A 3UM5A 3KY8A 1DLSA 3D84X 5HSRA 3JWCA 4KJJA 4OR7A 5HQZA 4FGHA 3FQCA 1RE7A 4DFRA 3D80A 3TQ8A 1PDBA 3QLRA 3F0SX 4OSGA 1SEJA 3FRFX 1KLKA 2AZNA 1IA1A 2ITHA 3IA4A 1MVTA 4QJCA 2ZZAA 1D1GA 3M09A 1DR5A 3SAIA 1PD9A 2H2QA 3IRMA 3RO9A 4ECKA 1RG7A 4KY8A 3Q1HA 4M7VA 1LUDA 1M7AA 1JUVA 3JWFA 3EIGA 4KNEA 5CCCA 2KGKA 3UM6A 1S3YA 3CSEA 3FRBX 1RD7A 4H97A 4PSTA 3IRNA 1DR6A 5EAJA 1DLRA 1DG7A 1DHFA 1DREA 2W3MA 3QLZA 2BLBA 2ANQA 3QGTA 4IXFX 4IXED 2CD2A 1U71A 5HI6A 3FQVA 4XT6A 4HA7A 3GHWA 3EEKA 4IXGX 3FQOA 1DR3A 3QLWA 3FQZA 4P66A 3RG9A 4QHVA 3DAUA 4H95A 3FS6A 5CC9A 3SGYA 4DDRA 3EX8A 3NXYA 4P3RA 1M78A 4KL9A 4PSSA 5HF2X 1ZDRA 8DFRA 4Q67A 3NRRA 2OBCA 5HVEA 5DXVA 3QLSA 1U70A 4FHBA 4LEKX 3TD8A 5HSUA 3F91A 3NXRA 3SA1A 1VDRA 3F8ZA 4Q0EA 1KMSA 1RA9A 1CZ3A 5ECXA 3UM8A 4M6JA 3NXVA 1BOZA 5JA3A 4G95A 4Q0DA 1DR4A 3IA5A 1AO8A 5FDAA 3DL6A 5HF0X 3FRDX 4DP3A 2XW7A 3JVXA 3S9UA 2FZIA 3I3RA 3SRQX 1DR2A 1HFPA 4KLXA 4X5HA 4ELFA 1DYHA 4KAKA 1S3UA 3F0UX 3OAFA 2QK8A 4KFJA 4PTJA 3ZPCA 5HQYA 3NZDA 1CD2A 1IA3A 1DRHA 4I1NA 3NZAX 4H98A 3QL3A 3NTZA 1RX3A 1E26A 3QLXA 3N0HA 5ECCA 1DYIA 3TQAA 1DDSA 1OHJA 4XT7A 5U27A 4XT5A 4KY4A 3FYVX 3KFYA 4X5IA 3JTWA 3IX9A 2W3VA 4G3MA 3SA2A 1DRBA 4PDJA 4HOEA 1J3JA 4EJ1A 2D5NA 3L3RA 1DR7A 1AOEA 2B3ZA 3NZCX 1DR1A 3SH2A 1RF7A 4GH8A 3S7AA 2DHFA 2BLAA 2L28A 4M6KA 1TDRA 3NZ9X 4XT8A 2W9HA 4QJZD 3SRWX 3QFXA 4P68A 2INQA 4RGCA 1RX1A 2FZHA 4KYAA 3JWMA 1DHIA 1DDRA 1RX4A 2JYBA 1DHJA 1RX5A 3K2HA 3JW3A 4DPDA 3DGAA 5U26A 4QLGA 3JSUA 4M7UA 4LAEX 3NXXA 5HVBA 2O7PA 3QYLA 1IA2A 1YHOA 2ANOA 4NX7A 3CL9A 2W9TA 4KBNA 4XE6X 2W3AA 3CD2A 3M08A 3QLYA 2DRCA 3NZBX 3OCHA 4KEBA 3GYFA 2W3WA 4X5JA 4XRBA 4ELGA 4ELEA 2HXVA 1PD8A 4Q6AA 4QLFA 3TQBA 3DFRA 3DG8A 2GD9A 1J3KA 3EEJA 1S3VA 1RX8A 4X5GA 3NZ6X 5HT5A 1RB2A 1JOLA 4HOFA 1DIUA 4PSYA 1DRAA 1RX9A 3K45A 4PTHA 3QYOA 4KJKA 3ZPGA 4ELBA 5HT4A 4TU5X 5JG0X 4XT4A 3NXTA 1DRFA 4EIZA 1DAJA 2LF1A 3SQYX 4EIGA 5DFRA 4ELHA 1DYJA 3HJ3A 3EELA 1RA8A 3R33A 3VCOA 3KGYA 3JWKA 4EILA 3F0VX 1RA1A 4HOGA 4QI9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NX6 A;  3FQ0 A;  1DF7 A;  5HPB A;  1RB3 A;  3SRU X;  4KJL A;  3TQ9 A;  3KJS A;  2FZJ A;  2BLC A;  3NXO A;  1DYR A;  1LY4 A;  4QLE A;  3QG2 A;  3E0B A;  3SRR X;  1J3I A;  2W9S A;  3FY9 X;  1VJ3 A;  2W3B A;  4LAG X;  3F0Q X;  3F0B X;  3FRE X;  4HA9 A;  1BZF A;  3CLB A;  5E8Q A;  1M79 A;  3HBB A;  1LY3 A;  3INV A;  1RX2 A;  3FY8 X;  3I8A X;  1JOM A;  3GHV A;  4FGG A;  3FL8 A;  3FRA X;  3EEM A;  3ROA A;  1DG8 A;  1U72 A;  3DAT A;  3F8Y A;  3GHC A;  6DFR A;  2W9G A;  3DRC A;  1RA2 A;  3FQF A;  1OHK A;  3KJR A;  3IRO A;  4LAH X;  1QZF A;  2BL9 A;  1KMV A;  4G8Z X;  4KM2 A;  4H96 A;  4M2X A;  1S3W A;  3K47 A;  3S3V A;  2P4G A;  2G6V A;  2OIP A;  2HM9 A;  4KD7 A;  1AI9 A;  3SRS X;  3F0X X;  3FYW X;  3DL5 A;  3JW5 A;  4DPH A;  3K74 A;  4P3Q A;  4M6L A;  4XEC X;  7DFR A;  2D0K A;  4X5F A;  2C2T A;  1RX7 A;  4CD2 A;  1RC4 A;  1DG5 A;  1DIS A;  2C2S A;  1HFR A;  1HFQ A;  1RH3 A;  1RX6 A;  3NU0 A;  1MVS A;  2HQP A;  3LG4 A;  2CIG A;  3SR5 X;  3GI2 A;  5HUI A;  1IA4 A;  4I13 A;  3QL0 A;  1RA3 A;  4KM0 A;  3FL9 A;  3UM5 A;  3KY8 A;  1DLS A;  3D84 X;  5HSR A;  3JWC A;  4KJJ A;  4OR7 A;  5HQZ A;  4FGH A;  3FQC A;  1RE7 A;  4DFR A;  3D80 A;  3TQ8 A;  1PDB A;  3QLR A;  3F0S X;  4OSG A;  1SEJ A;  3FRF X;  1KLK A;  2AZN A;  1IA1 A;  2ITH A;  3IA4 A;  1MVT A;  4QJC A;  2ZZA A;  1D1G A;  3M09 A;  1DR5 A;  3SAI A;  1PD9 A;  2H2Q A;  3IRM A;  3RO9 A;  4ECK A;  1RG7 A;  4KY8 A;  3Q1H A;  4M7V A;  1LUD A;  1M7A A;  1JUV A;  3JWF A;  3EIG A;  4KNE A;  5CCC A;  2KGK A;  3UM6 A;  1S3Y A;  3CSE A;  3FRB X;  1RD7 A;  4H97 A;  4PST A;  3IRN A;  1DR6 A;  5EAJ A;  1DLR A;  1DG7 A;  1DHF A;  1DRE A;  2W3M A;  3QLZ A;  2BLB A;  2ANQ A;  3QGT A;  4IXF X;  4IXE D;  2CD2 A;  1U71 A;  5HI6 A;  3FQV A;  4XT6 A;  4HA7 A;  3GHW A;  3EEK A;  4IXG X;  3FQO A;  1DR3 A;  3QLW A;  3FQZ A;  4P66 A;  3RG9 A;  4QHV A;  3DAU A;  4H95 A;  3FS6 A;  5CC9 A;  3SGY A;  4DDR A;  3EX8 A;  3NXY A;  4P3R A;  1M78 A;  4KL9 A;  4PSS A;  5HF2 X;  1ZDR A;  8DFR A;  4Q67 A;  3NRR A;  2OBC A;  5HVE A;  5DXV A;  3QLS A;  1U70 A;  4FHB A;  4LEK X;  3TD8 A;  5HSU A;  3F91 A;  3NXR A;  3SA1 A;  1VDR A;  3F8Z A;  4Q0E A;  1KMS A;  1RA9 A;  1CZ3 A;  5ECX A;  3UM8 A;  4M6J A;  3NXV A;  1BOZ A;  5JA3 A;  4G95 A;  4Q0D A;  1DR4 A;  3IA5 A;  1AO8 A;  5FDA A;  3DL6 A;  5HF0 X;  3FRD X;  4DP3 A;  2XW7 A;  3JVX A;  3S9U A;  2FZI A;  3I3R A;  3SRQ X;  1DR2 A;  1HFP A;  4KLX A;  4X5H A;  4ELF A;  1DYH A;  4KAK A;  1S3U A;  3F0U X;  3OAF A;  2QK8 A;  4KFJ A;  4PTJ A;  3ZPC A;  5HQY A;  3NZD A;  1CD2 A;  1IA3 A;  1DRH A;  4I1N A;  3NZA X;  4H98 A;  3QL3 A;  3NTZ A;  1RX3 A;  1E26 A;  3QLX A;  3N0H A;  5ECC A;  1DYI A;  3TQA A;  1DDS A;  1OHJ A;  4XT7 A;  5U27 A;  4XT5 A;  4KY4 A;  3FYV X;  3KFY A;  4X5I A;  3JTW A;  3IX9 A;  2W3V A;  4G3M A;  3SA2 A;  1DRB A;  4PDJ A;  4HOE A;  1J3J A;  4EJ1 A;  2D5N A;  3L3R A;  1DR7 A;  1AOE A;  2B3Z A;  3NZC X;  1DR1 A;  3SH2 A;  1RF7 A;  4GH8 A;  3S7A A;  2DHF A;  2BLA A;  2L28 A;  4M6K A;  1TDR A;  3NZ9 X;  4XT8 A;  2W9H A;  4QJZ D;  3SRW X;  3QFX A;  4P68 A;  2INQ A;  4RGC A;  1RX1 A;  2FZH A;  4KYA A;  3JWM A;  1DHI A;  1DDR A;  1RX4 A;  2JYB A;  1DHJ A;  1RX5 A;  3K2H A;  3JW3 A;  4DPD A;  3DGA A;  5U26 A;  4QLG A;  3JSU A;  4M7U A;  4LAE X;  3NXX A;  5HVB A;  2O7P A;  3QYL A;  1IA2 A;  1YHO A;  2ANO A;  4NX7 A;  3CL9 A;  2W9T A;  4KBN A;  4XE6 X;  2W3A A;  3CD2 A;  3M08 A;  3QLY A;  2DRC A;  3NZB X;  3OCH A;  4KEB A;  3GYF A;  2W3W A;  4X5J A;  4XRB A;  4ELG A;  4ELE A;  2HXV A;  1PD8 A;  4Q6A A;  4QLF A;  3TQB A;  3DFR A;  3DG8 A;  2GD9 A;  1J3K A;  3EEJ A;  1S3V A;  1RX8 A;  4X5G A;  3NZ6 X;  5HT5 A;  1RB2 A;  1JOL A;  4HOF A;  1DIU A;  4PSY A;  1DRA A;  1RX9 A;  3K45 A;  4PTH A;  3QYO A;  4KJK A;  3ZPG A;  4ELB A;  5HT4 A;  4TU5 X;  5JG0 X;  4XT4 A;  3NXT A;  1DRF A;  4EIZ A;  1DAJ A;  2LF1 A;  3SQY X;  4EIG A;  5DFR A;  4ELH A;  1DYJ A;  3HJ3 A;  3EEL A;  1RA8 A;  3R33 A;  3VCO A;  3KGY A;  3JWK A;  4EIL A;  3F0V X;  1RA1 A;  4HOG A;  4QI9 A; 
#chains in the Genus database with same CATH topology
 4NX6 A;  3FQ0 A;  1DF7 A;  5HPB A;  1RB3 A;  3SRU X;  4KJL A;  3TQ9 A;  3KJS A;  2FZJ A;  2BLC A;  3NXO A;  1DYR A;  1LY4 A;  4QLE A;  3QG2 A;  3E0B A;  3SRR X;  1J3I A;  2W9S A;  3FY9 X;  1VJ3 A;  2W3B A;  4LAG X;  3F0Q X;  3F0B X;  3FRE X;  4HA9 A;  1BZF A;  3CLB A;  5E8Q A;  1M79 A;  3HBB A;  1LY3 A;  3INV A;  1RX2 A;  3FY8 X;  3I8A X;  1JOM A;  3GHV A;  4FGG A;  3FL8 A;  3FRA X;  3EEM A;  3ROA A;  1DG8 A;  1U72 A;  3DAT A;  3F8Y A;  3GHC A;  6DFR A;  2W9G A;  3DRC A;  1RA2 A;  3FQF A;  1OHK A;  3KJR A;  3IRO A;  4LAH X;  1QZF A;  2BL9 A;  1KMV A;  4G8Z X;  4KM2 A;  4H96 A;  4M2X A;  1S3W A;  3K47 A;  3S3V A;  2P4G A;  2G6V A;  2OIP A;  2HM9 A;  4KD7 A;  1AI9 A;  3SRS X;  3F0X X;  3FYW X;  3DL5 A;  3JW5 A;  4DPH A;  3K74 A;  4P3Q A;  4M6L A;  4XEC X;  7DFR A;  2D0K A;  4X5F A;  2C2T A;  1RX7 A;  4CD2 A;  1RC4 A;  1DG5 A;  1DIS A;  2C2S A;  1HFR A;  1HFQ A;  1RH3 A;  1RX6 A;  3NU0 A;  1MVS A;  2HQP A;  3LG4 A;  2CIG A;  3SR5 X;  3GI2 A;  5HUI A;  1IA4 A;  4I13 A;  3QL0 A;  1RA3 A;  4KM0 A;  3FL9 A;  3UM5 A;  3KY8 A;  1DLS A;  3D84 X;  5HSR A;  3JWC A;  4KJJ A;  4OR7 A;  5HQZ A;  4FGH A;  3FQC A;  1RE7 A;  4DFR A;  3D80 A;  3TQ8 A;  1PDB A;  3QLR A;  3F0S X;  4OSG A;  1SEJ A;  3FRF X;  1KLK A;  2AZN A;  1IA1 A;  2ITH A;  3IA4 A;  1MVT A;  4QJC A;  2ZZA A;  1D1G A;  3M09 A;  1DR5 A;  3SAI A;  1PD9 A;  2H2Q A;  3IRM A;  3RO9 A;  4ECK A;  1RG7 A;  4KY8 A;  3Q1H A;  4M7V A;  1LUD A;  1M7A A;  1JUV A;  3JWF A;  3EIG A;  4KNE A;  5CCC A;  2KGK A;  3UM6 A;  1S3Y A;  3CSE A;  3FRB X;  1RD7 A;  4H97 A;  4PST A;  3IRN A;  1DR6 A;  5EAJ A;  1DLR A;  1DG7 A;  1DHF A;  1DRE A;  2W3M A;  3QLZ A;  2BLB A;  2ANQ A;  3QGT A;  4IXF X;  4IXE D;  2CD2 A;  1U71 A;  5HI6 A;  3FQV A;  4XT6 A;  4HA7 A;  3GHW A;  3EEK A;  4IXG X;  3FQO A;  1DR3 A;  3QLW A;  3FQZ A;  4P66 A;  3RG9 A;  4QHV A;  3DAU A;  4H95 A;  3FS6 A;  5CC9 A;  3SGY A;  4DDR A;  3EX8 A;  3NXY A;  4P3R A;  1M78 A;  4KL9 A;  4PSS A;  5HF2 X;  1ZDR A;  8DFR A;  4Q67 A;  3NRR A;  2OBC A;  5HVE A;  5DXV A;  3QLS A;  1U70 A;  4FHB A;  4LEK X;  3TD8 A;  5HSU A;  3F91 A;  3NXR A;  3SA1 A;  1VDR A;  3F8Z A;  4Q0E A;  1KMS A;  1RA9 A;  1CZ3 A;  5ECX A;  3UM8 A;  4M6J A;  3NXV A;  1BOZ A;  5JA3 A;  4G95 A;  4Q0D A;  1DR4 A;  3IA5 A;  1AO8 A;  5FDA A;  3DL6 A;  5HF0 X;  3FRD X;  4DP3 A;  2XW7 A;  3JVX A;  3S9U A;  2FZI A;  3I3R A;  3SRQ X;  1DR2 A;  1HFP A;  4KLX A;  4X5H A;  4ELF A;  1DYH A;  4KAK A;  1S3U A;  3F0U X;  3OAF A;  2QK8 A;  4KFJ A;  4PTJ A;  3ZPC A;  5HQY A;  3NZD A;  1CD2 A;  1IA3 A;  1DRH A;  4I1N A;  3NZA X;  4H98 A;  3QL3 A;  3NTZ A;  1RX3 A;  1E26 A;  3QLX A;  3N0H A;  5ECC A;  1DYI A;  3TQA A;  1DDS A;  1OHJ A;  4XT7 A;  5U27 A;  4XT5 A;  4KY4 A;  3FYV X;  3KFY A;  4X5I A;  3JTW A;  3IX9 A;  2W3V A;  4G3M A;  3SA2 A;  1DRB A;  4PDJ A;  4HOE A;  1J3J A;  4EJ1 A;  2D5N A;  3L3R A;  1DR7 A;  1AOE A;  2B3Z A;  3NZC X;  1DR1 A;  3SH2 A;  1RF7 A;  4GH8 A;  3S7A A;  2DHF A;  2BLA A;  2L28 A;  4M6K A;  1TDR A;  3NZ9 X;  4XT8 A;  2W9H A;  4QJZ D;  3SRW X;  3QFX A;  4P68 A;  2INQ A;  4RGC A;  1RX1 A;  2FZH A;  4KYA A;  3JWM A;  1DHI A;  1DDR A;  1RX4 A;  2JYB A;  1DHJ A;  1RX5 A;  3K2H A;  3JW3 A;  4DPD A;  3DGA A;  5U26 A;  4QLG A;  3JSU A;  4M7U A;  4LAE X;  3NXX A;  5HVB A;  2O7P A;  3QYL A;  1IA2 A;  1YHO A;  2ANO A;  4NX7 A;  3CL9 A;  2W9T A;  4KBN A;  4XE6 X;  2W3A A;  3CD2 A;  3M08 A;  3QLY A;  2DRC A;  3NZB X;  3OCH A;  4KEB A;  3GYF A;  2W3W A;  4X5J A;  4XRB A;  4ELG A;  4ELE A;  2HXV A;  1PD8 A;  4Q6A A;  4QLF A;  3TQB A;  3DFR A;  3DG8 A;  2GD9 A;  1J3K A;  3EEJ A;  1S3V A;  1RX8 A;  4X5G A;  3NZ6 X;  5HT5 A;  1RB2 A;  1JOL A;  4HOF A;  1DIU A;  4PSY A;  1DRA A;  1RX9 A;  3K45 A;  4PTH A;  3QYO A;  4KJK A;  3ZPG A;  4ELB A;  5HT4 A;  4TU5 X;  5JG0 X;  4XT4 A;  3NXT A;  1DRF A;  4EIZ A;  1DAJ A;  2LF1 A;  3SQY X;  4EIG A;  5DFR A;  4ELH A;  1DYJ A;  3HJ3 A;  3EEL A;  1RA8 A;  3R33 A;  3VCO A;  3KGY A;  3JWK A;  4EIL A;  3F0V X;  1RA1 A;  4HOG A;  4QI9 A; 
#chains in the Genus database with same CATH homology
 4NX6 A;  3FQ0 A;  1DF7 A;  5HPB A;  1RB3 A;  3SRU X;  4KJL A;  3TQ9 A;  3KJS A;  2FZJ A;  2BLC A;  3NXO A;  1DYR A;  1LY4 A;  4QLE A;  3QG2 A;  3E0B A;  3SRR X;  1J3I A;  2W9S A;  3FY9 X;  1VJ3 A;  2W3B A;  4LAG X;  3F0Q X;  3F0B X;  3FRE X;  4HA9 A;  1BZF A;  3CLB A;  5E8Q A;  1M79 A;  3HBB A;  1LY3 A;  3INV A;  1RX2 A;  3FY8 X;  3I8A X;  1JOM A;  3GHV A;  4FGG A;  3FL8 A;  3FRA X;  3EEM A;  3ROA A;  1DG8 A;  1U72 A;  3DAT A;  3F8Y A;  3GHC A;  6DFR A;  2W9G A;  3DRC A;  1RA2 A;  3FQF A;  1OHK A;  3KJR A;  3IRO A;  4LAH X;  1QZF A;  2BL9 A;  1KMV A;  4G8Z X;  4KM2 A;  4H96 A;  4M2X A;  1S3W A;  3K47 A;  3S3V A;  2P4G A;  2G6V A;  2OIP A;  2HM9 A;  4KD7 A;  1AI9 A;  3SRS X;  3F0X X;  3FYW X;  3DL5 A;  3JW5 A;  4DPH A;  3K74 A;  4P3Q A;  4M6L A;  4XEC X;  7DFR A;  2D0K A;  4X5F A;  2C2T A;  1RX7 A;  4CD2 A;  1RC4 A;  1DG5 A;  1DIS A;  2C2S A;  1HFR A;  1HFQ A;  1RH3 A;  1RX6 A;  3NU0 A;  1MVS A;  2HQP A;  3LG4 A;  2CIG A;  3SR5 X;  3GI2 A;  5HUI A;  1IA4 A;  4I13 A;  3QL0 A;  1RA3 A;  4KM0 A;  3FL9 A;  3UM5 A;  3KY8 A;  1DLS A;  3D84 X;  5HSR A;  3JWC A;  4KJJ A;  4OR7 A;  5HQZ A;  4FGH A;  3FQC A;  1RE7 A;  4DFR A;  3D80 A;  3TQ8 A;  1PDB A;  3QLR A;  3F0S X;  4OSG A;  1SEJ A;  3FRF X;  1KLK A;  2AZN A;  1IA1 A;  2ITH A;  3IA4 A;  1MVT A;  4QJC A;  2ZZA A;  1D1G A;  3M09 A;  1DR5 A;  3SAI A;  1PD9 A;  2H2Q A;  3IRM A;  3RO9 A;  4ECK A;  1RG7 A;  4KY8 A;  3Q1H A;  4M7V A;  1LUD A;  1M7A A;  1JUV A;  3JWF A;  3EIG A;  4KNE A;  5CCC A;  2KGK A;  3UM6 A;  1S3Y A;  3CSE A;  3FRB X;  1RD7 A;  4H97 A;  4PST A;  3IRN A;  1DR6 A;  5EAJ A;  1DLR A;  1DG7 A;  1DHF A;  1DRE A;  2W3M A;  3QLZ A;  2BLB A;  2ANQ A;  3QGT A;  4IXF X;  4IXE D;  2CD2 A;  1U71 A;  5HI6 A;  3FQV A;  4XT6 A;  4HA7 A;  3GHW A;  3EEK A;  4IXG X;  3FQO A;  1DR3 A;  3QLW A;  3FQZ A;  4P66 A;  3RG9 A;  4QHV A;  3DAU A;  4H95 A;  3FS6 A;  5CC9 A;  3SGY A;  4DDR A;  3EX8 A;  3NXY A;  4P3R A;  1M78 A;  4KL9 A;  4PSS A;  5HF2 X;  1ZDR A;  8DFR A;  4Q67 A;  3NRR A;  2OBC A;  5HVE A;  5DXV A;  3QLS A;  1U70 A;  4FHB A;  4LEK X;  3TD8 A;  5HSU A;  3F91 A;  3NXR A;  3SA1 A;  1VDR A;  3F8Z A;  4Q0E A;  1KMS A;  1RA9 A;  1CZ3 A;  5ECX A;  3UM8 A;  4M6J A;  3NXV A;  1BOZ A;  5JA3 A;  4G95 A;  4Q0D A;  1DR4 A;  3IA5 A;  1AO8 A;  5FDA A;  3DL6 A;  5HF0 X;  3FRD X;  4DP3 A;  2XW7 A;  3JVX A;  3S9U A;  2FZI A;  3I3R A;  3SRQ X;  1DR2 A;  1HFP A;  4KLX A;  4X5H A;  4ELF A;  1DYH A;  4KAK A;  1S3U A;  3F0U X;  3OAF A;  2QK8 A;  4KFJ A;  4PTJ A;  3ZPC A;  5HQY A;  3NZD A;  1CD2 A;  1IA3 A;  1DRH A;  4I1N A;  3NZA X;  4H98 A;  3QL3 A;  3NTZ A;  1RX3 A;  1E26 A;  3QLX A;  3N0H A;  5ECC A;  1DYI A;  3TQA A;  1DDS A;  1OHJ A;  4XT7 A;  5U27 A;  4XT5 A;  4KY4 A;  3FYV X;  3KFY A;  4X5I A;  3JTW A;  3IX9 A;  2W3V A;  4G3M A;  3SA2 A;  1DRB A;  4PDJ A;  4HOE A;  1J3J A;  4EJ1 A;  2D5N A;  3L3R A;  1DR7 A;  1AOE A;  2B3Z A;  3NZC X;  1DR1 A;  3SH2 A;  1RF7 A;  4GH8 A;  3S7A A;  2DHF A;  2BLA A;  2L28 A;  4M6K A;  1TDR A;  3NZ9 X;  4XT8 A;  2W9H A;  4QJZ D;  3SRW X;  3QFX A;  4P68 A;  2INQ A;  4RGC A;  1RX1 A;  2FZH A;  4KYA A;  3JWM A;  1DHI A;  1DDR A;  1RX4 A;  2JYB A;  1DHJ A;  1RX5 A;  3K2H A;  3JW3 A;  4DPD A;  3DGA A;  5U26 A;  4QLG A;  3JSU A;  4M7U A;  4LAE X;  3NXX A;  5HVB A;  2O7P A;  3QYL A;  1IA2 A;  1YHO A;  2ANO A;  4NX7 A;  3CL9 A;  2W9T A;  4KBN A;  4XE6 X;  2W3A A;  3CD2 A;  3M08 A;  3QLY A;  2DRC A;  3NZB X;  3OCH A;  4KEB A;  3GYF A;  2W3W A;  4X5J A;  4XRB A;  4ELG A;  4ELE A;  2HXV A;  1PD8 A;  4Q6A A;  4QLF A;  3TQB A;  3DFR A;  3DG8 A;  2GD9 A;  1J3K A;  3EEJ A;  1S3V A;  1RX8 A;  4X5G A;  3NZ6 X;  5HT5 A;  1RB2 A;  1JOL A;  4HOF A;  1DIU A;  4PSY A;  1DRA A;  1RX9 A;  3K45 A;  4PTH A;  3QYO A;  4KJK A;  3ZPG A;  4ELB A;  5HT4 A;  4TU5 X;  5JG0 X;  4XT4 A;  3NXT A;  1DRF A;  4EIZ A;  1DAJ A;  2LF1 A;  3SQY X;  4EIG A;  5DFR A;  4ELH A;  1DYJ A;  3HJ3 A;  3EEL A;  1RA8 A;  3R33 A;  3VCO A;  3KGY A;  3JWK A;  4EIL A;  3F0V X;  1RA1 A;  4HOG A;  4QI9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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