5HVBA

5-methyl-6-(1-naphthylthio)thieno[2,3-d]pyrimidine 2,4-diamine
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
186
structure length
186
Chain Sequence
VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human dihydrofolate reductase ternary complex with a series of fluorine substituted 5-methyl-6-(1-napthylthio)[2,3-d]pyrimidine-2,4-diamines
rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Homo sapiens
molecule keywords Dihydrofolate reductase
total genus 54
structure length 186
sequence length 186
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2016-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 5hvbA00
2HM9A 5JA3A 1KMVA 3R33A 1S3WA 3DL5A 4QJCA 1RB2A 3FRBX 4TU5X 2INQA 4EIZA 4G95A 1IA2A 2W9HA 3SA2A 2W9SA 2DHFA 1OHJA 4QLGA 1DYIA 3DG8A 1RG7A 4KD7A 3FQCA 1KLKA 2C2TA 2W9TA 2W3VA 1LUDA 5HVBA 4M7UA 5HT4A 1SEJA 3TQ8A 1DISA 4OSGA 3KGYA 2CD2A 3NTZA 4XECX 5HI6A 1DYJA 4NX7A 4KY8A 3NXYA 3DFRA 1TDRA 2JYBA 3DL6A 3IROA 5DXVA 1DRAA 2QK8A 4HA9A 3S9UA 1J3JA 3QLRA 5HQZA 1RX1A 2W3MA 3IRMA 3NZ6X 4PTHA 2FZHA 1RD7A 2XW7A 4KYAA 5HUIA 4M6LA 1RA9A 3M08A 3SGYA 1IA1A 3JWKA 1DRFA 3F8ZA 4XT5A 3FRDX 4RGCA 1M79A 4KEBA 4EILA 2AZNA 4IXED 3S7AA 4KJJA 3SR5X 3JWMA 3SQYX 4I1NA 4Q6AA 4LAHX 1RX6A 2OBCA 4Q67A 4H98A 3FQFA 4HOFA 5U27A 2OIPA 1DDRA 1DR7A 4KL9A 2B3ZA 2GD9A 4Q0EA 3QLXA 3D80A 1RH3A 3GHWA 4LAEX 1AI9A 3EEJA 1DLSA 1DHIA 3QYLA 2H2QA 3TQ9A 4EJ1A 3TQAA 3SA1A 5CCCA 1DHFA 3IA5A 4KJLA 5HF0X 3IRNA 3NZBX 1DG5A 2HXVA 3K2HA 3FS6A 1DR3A 3EEKA 1BOZA 1RX8A 2W3AA 4M6KA 1DR2A 3M09A 2D0KA 4DFRA 3NU0A 4GH8A 4OR7A 3DAUA 1PD9A 2W9GA 3NXOA 3NZ9X 1ZDRA 4QLEA 3F0BX 5HF2X 4ECKA 4QHVA 3K45A 3Q1HA 1E26A 1DG8A 4ELBA 2ZZAA 2FZIA 4H96A 1U71A 4KM2A 3GI2A 1U72A 4QJZD 3F8YA 1DHJA 3JTWA 5ECXA 3INVA 4H97A 1S3UA 4PDJA 2BLCA 3NZAX 2LF1A 3F0XX 3NXTA 1OHKA 3SRUX 2W3BA 4FGGA 1D1GA 3JVXA 3SH2A 1HFPA 1PD8A 2ITHA 3IA4A 3UM5A 1MVSA 1MVTA 4PTJA 1DRBA 4IXGX 1HFRA 3FRFX 7DFRA 3ZPCA 3DATA 3L3RA 4CD2A 3CSEA 1RE7A 3EIGA 1RA8A 4LAGX 4XE6X 4ELEA 4QI9A 4NX6A 1S3YA 4KAKA 2C2SA 5JG0X 3OAFA 3FQZA 3QLYA 3RG9A 4DPHA 3FQOA 4X5GA 1RX7A 4P68A 4ELFA 4HOGA 4M2XA 4G8ZX 4FGHA 3JW3A 3EEMA 4XRBA 4Q0DA 3N0HA 3NXXA 4HOEA 1VDRA 1IA3A 2G6VA 5HPBA 1CD2A 1LY4A 1M7AA 3OCHA 1JOLA 1RF7A 5E8QA 1JUVA 6DFRA 3K74A 2L28A 3FQVA 5U26A 3KJSA 1DLRA 3EX8A 1VJ3A 3SRSX 1RC4A 3DGAA 2KGKA 1BZFA 3KY8A 1YHOA 3GYFA 3HJ3A 4IXFX 3S3VA 1DRHA 5HVEA 5HQYA 4EIGA 3GHCA 3K47A 3EELA 4XT7A 3FL8A 3RO9A 3I3RA 3HBBA 1DR6A 1U70A 3JSUA 3SRRX 3CLBA 4X5HA 4LEKX 4KLXA 3LG4A 3NRRA 1DR1A 1DYRA 1JOMA 5DFRA 3SAIA 3F0QX 3FY8X 3SRWX 4DPDA 1CZ3A 3NXVA 1RX5A 1RX4A 1RX9A 3KJRA 4I13A 4XT4A 3D84X 2O7PA 1RA3A 2BL9A 3NZCX 3IX9A 3QGTA 4KFJA 1QZFA 4KNEA 4X5FA 2CIGA 3UM6A 1KMSA 3ZPGA 3QL0A 4DDRA 3F0UX 3NZDA 3QG2A 2DRCA 3FRAX 3JWCA 3QLSA 3QL3A 4XT8A 2HQPA 3QFXA 3TQBA 1J3IA 3FY9X 4PSTA 1IA4A 4P3QA 4ELGA 4X5JA 1RX3A 1RA2A 3SRQX 1PDBA 2ANOA 4KJKA 4ELHA 1DR4A 3UM8A 4XT6A 5HT5A 3QLZA 1LY3A 1DDSA 1DAJA 4M6JA 3E0BA 1RA1A 3F91A 4M7VA 3FQ0A 2ANQA 2D5NA 2FZJA 4PSSA 4KM0A 1S3VA 1M78A 4PSYA 5HSRA 4P66A 2P4GA 4QLFA 4HA7A 1DG7A 1DR5A 3CD2A 1HFQA 4X5IA 1AOEA 5CC9A 3I8AX 3QLWA 8DFRA 1J3KA 2BLBA 3FL9A 1DF7A 3F0VX 3KFYA 3FYWX 3GHVA 1DIUA 5ECCA 3JWFA 4DP3A 2BLAA 1DREA 3ROAA 5EAJA 3JW5A 4KY4A 3DRCA 4G3MA 3FYVX 2W3WA 3TD8A 3CL9A 1AO8A 3QYOA 3F0SX 4H95A 3NXRA 5HSUA 5FDAA 1RX2A 4P3RA 4FHBA 1RB3A 3FREX 1DYHA 3VCOA 4KBNA
chains in the Genus database with same CATH superfamily
2HM9A 5JA3A 1KMVA 3R33A 1S3WA 3DL5A 4QJCA 1RB2A 3FRBX 4TU5X 2INQA 4EIZA 4G95A 1IA2A 2W9HA 3SA2A 2W9SA 2DHFA 1OHJA 4QLGA 1DYIA 3DG8A 1RG7A 4KD7A 3FQCA 1KLKA 2C2TA 2W9TA 2W3VA 1LUDA 5HVBA 4M7UA 5HT4A 1SEJA 3TQ8A 1DISA 4OSGA 3KGYA 2CD2A 3NTZA 4XECX 5HI6A 1DYJA 4NX7A 4KY8A 3NXYA 3DFRA 1TDRA 2JYBA 3DL6A 3IROA 5DXVA 1DRAA 2QK8A 4HA9A 3S9UA 1J3JA 3QLRA 5HQZA 1RX1A 2W3MA 3IRMA 3NZ6X 4PTHA 2FZHA 1RD7A 2XW7A 4KYAA 5HUIA 4M6LA 1RA9A 3M08A 3SGYA 1IA1A 3JWKA 1DRFA 3F8ZA 4XT5A 3FRDX 4RGCA 1M79A 4KEBA 4EILA 2AZNA 4IXED 3S7AA 4KJJA 3SR5X 3JWMA 3SQYX 4I1NA 4Q6AA 4LAHX 1RX6A 2OBCA 4Q67A 4H98A 3FQFA 4HOFA 5U27A 2OIPA 1DDRA 1DR7A 4KL9A 2B3ZA 2GD9A 4Q0EA 3QLXA 3D80A 1RH3A 3GHWA 4LAEX 1AI9A 3EEJA 1DLSA 1DHIA 3QYLA 2H2QA 3TQ9A 4EJ1A 3TQAA 3SA1A 5CCCA 1DHFA 3IA5A 4KJLA 5HF0X 3IRNA 3NZBX 1DG5A 2HXVA 3K2HA 3FS6A 1DR3A 3EEKA 1BOZA 1RX8A 2W3AA 4M6KA 1DR2A 3M09A 2D0KA 4DFRA 3NU0A 4GH8A 4OR7A 3DAUA 1PD9A 2W9GA 3NXOA 3NZ9X 1ZDRA 4QLEA 3F0BX 5HF2X 4ECKA 4QHVA 3K45A 3Q1HA 1E26A 1DG8A 4ELBA 2ZZAA 2FZIA 4H96A 1U71A 4KM2A 3GI2A 1U72A 4QJZD 3F8YA 1DHJA 3JTWA 5ECXA 3INVA 4H97A 1S3UA 4PDJA 2BLCA 3NZAX 2LF1A 3F0XX 3NXTA 1OHKA 3SRUX 2W3BA 4FGGA 1D1GA 3JVXA 3SH2A 1HFPA 1PD8A 2ITHA 3IA4A 3UM5A 1MVSA 1MVTA 4PTJA 1DRBA 4IXGX 1HFRA 3FRFX 7DFRA 3ZPCA 3DATA 3L3RA 4CD2A 3CSEA 1RE7A 3EIGA 1RA8A 4LAGX 4XE6X 4ELEA 4QI9A 4NX6A 1S3YA 4KAKA 2C2SA 5JG0X 3OAFA 3FQZA 3QLYA 3RG9A 4DPHA 3FQOA 4X5GA 1RX7A 4P68A 4ELFA 4HOGA 4M2XA 4G8ZX 4FGHA 3JW3A 3EEMA 4XRBA 4Q0DA 3N0HA 3NXXA 4HOEA 1VDRA 1IA3A 2G6VA 5HPBA 1CD2A 1LY4A 1M7AA 3OCHA 1JOLA 1RF7A 5E8QA 1JUVA 6DFRA 3K74A 2L28A 3FQVA 5U26A 3KJSA 1DLRA 3EX8A 1VJ3A 3SRSX 1RC4A 3DGAA 2KGKA 1BZFA 3KY8A 1YHOA 3GYFA 3HJ3A 4IXFX 3S3VA 1DRHA 5HVEA 5HQYA 4EIGA 3GHCA 3K47A 3EELA 4XT7A 3FL8A 3RO9A 3I3RA 3HBBA 1DR6A 1U70A 3JSUA 3SRRX 3CLBA 4X5HA 4LEKX 4KLXA 3LG4A 3NRRA 1DR1A 1DYRA 1JOMA 5DFRA 3SAIA 3F0QX 3FY8X 3SRWX 4DPDA 1CZ3A 3NXVA 1RX5A 1RX4A 1RX9A 3KJRA 4I13A 4XT4A 3D84X 2O7PA 1RA3A 2BL9A 3NZCX 3IX9A 3QGTA 4KFJA 1QZFA 4KNEA 4X5FA 2CIGA 3UM6A 1KMSA 3ZPGA 3QL0A 4DDRA 3F0UX 3NZDA 3QG2A 2DRCA 3FRAX 3JWCA 3QLSA 3QL3A 4XT8A 2HQPA 3QFXA 3TQBA 1J3IA 3FY9X 4PSTA 1IA4A 4P3QA 4ELGA 4X5JA 1RX3A 1RA2A 3SRQX 1PDBA 2ANOA 4KJKA 4ELHA 1DR4A 3UM8A 4XT6A 5HT5A 3QLZA 1LY3A 1DDSA 1DAJA 4M6JA 3E0BA 1RA1A 3F91A 4M7VA 3FQ0A 2ANQA 2D5NA 2FZJA 4PSSA 4KM0A 1S3VA 1M78A 4PSYA 5HSRA 4P66A 2P4GA 4QLFA 4HA7A 1DG7A 1DR5A 3CD2A 1HFQA 4X5IA 1AOEA 5CC9A 3I8AX 3QLWA 8DFRA 1J3KA 2BLBA 3FL9A 1DF7A 3F0VX 3KFYA 3FYWX 3GHVA 1DIUA 5ECCA 3JWFA 4DP3A 2BLAA 1DREA 3ROAA 5EAJA 3JW5A 4KY4A 3DRCA 4G3MA 3FYVX 2W3WA 3TD8A 3CL9A 1AO8A 3QYOA 3F0SX 4H95A 3NXRA 5HSUA 5FDAA 1RX2A 4P3RA 4FHBA 1RB3A 3FREX 1DYHA 3VCOA 4KBNA
chains in the Genus database with same CATH topology
2HM9A 5JA3A 1KMVA 3R33A 1S3WA 3DL5A 4QJCA 1RB2A 3FRBX 4TU5X 2INQA 4EIZA 4G95A 1IA2A 2W9HA 3SA2A 2W9SA 2DHFA 1OHJA 4QLGA 1DYIA 3DG8A 1RG7A 4KD7A 3FQCA 1KLKA 2C2TA 2W9TA 2W3VA 1LUDA 5HVBA 4M7UA 5HT4A 1SEJA 3TQ8A 1DISA 4OSGA 3KGYA 2CD2A 3NTZA 4XECX 5HI6A 1DYJA 4NX7A 4KY8A 3NXYA 3DFRA 1TDRA 2JYBA 3DL6A 3IROA 5DXVA 1DRAA 2QK8A 4HA9A 3S9UA 1J3JA 3QLRA 5HQZA 1RX1A 2W3MA 3IRMA 3NZ6X 4PTHA 2FZHA 1RD7A 2XW7A 4KYAA 5HUIA 4M6LA 1RA9A 3M08A 3SGYA 1IA1A 3JWKA 1DRFA 3F8ZA 4XT5A 3FRDX 4RGCA 1M79A 4KEBA 4EILA 2AZNA 4IXED 3S7AA 4KJJA 3SR5X 3JWMA 3SQYX 4I1NA 4Q6AA 4LAHX 1RX6A 2OBCA 4Q67A 4H98A 3FQFA 4HOFA 5U27A 2OIPA 1DDRA 1DR7A 4KL9A 2B3ZA 2GD9A 4Q0EA 3QLXA 3D80A 1RH3A 3GHWA 4LAEX 1AI9A 3EEJA 1DLSA 1DHIA 3QYLA 2H2QA 3TQ9A 4EJ1A 3TQAA 3SA1A 5CCCA 1DHFA 3IA5A 4KJLA 5HF0X 3IRNA 3NZBX 1DG5A 2HXVA 3K2HA 3FS6A 1DR3A 3EEKA 1BOZA 1RX8A 2W3AA 4M6KA 1DR2A 3M09A 2D0KA 4DFRA 3NU0A 4GH8A 4OR7A 3DAUA 1PD9A 2W9GA 3NXOA 3NZ9X 1ZDRA 4QLEA 3F0BX 5HF2X 4ECKA 4QHVA 3K45A 3Q1HA 1E26A 1DG8A 4ELBA 2ZZAA 2FZIA 4H96A 1U71A 4KM2A 3GI2A 1U72A 4QJZD 3F8YA 1DHJA 3JTWA 5ECXA 3INVA 4H97A 1S3UA 4PDJA 2BLCA 3NZAX 2LF1A 3F0XX 3NXTA 1OHKA 3SRUX 2W3BA 4FGGA 1D1GA 3JVXA 3SH2A 1HFPA 1PD8A 2ITHA 3IA4A 3UM5A 1MVSA 1MVTA 4PTJA 1DRBA 4IXGX 1HFRA 3FRFX 7DFRA 3ZPCA 3DATA 3L3RA 4CD2A 3CSEA 1RE7A 3EIGA 1RA8A 4LAGX 4XE6X 4ELEA 4QI9A 4NX6A 1S3YA 4KAKA 2C2SA 5JG0X 3OAFA 3FQZA 3QLYA 3RG9A 4DPHA 3FQOA 4X5GA 1RX7A 4P68A 4ELFA 4HOGA 4M2XA 4G8ZX 4FGHA 3JW3A 3EEMA 4XRBA 4Q0DA 3N0HA 3NXXA 4HOEA 1VDRA 1IA3A 2G6VA 5HPBA 1CD2A 1LY4A 1M7AA 3OCHA 1JOLA 1RF7A 5E8QA 1JUVA 6DFRA 3K74A 2L28A 3FQVA 5U26A 3KJSA 1DLRA 3EX8A 1VJ3A 3SRSX 1RC4A 3DGAA 2KGKA 1BZFA 3KY8A 1YHOA 3GYFA 3HJ3A 4IXFX 3S3VA 1DRHA 5HVEA 5HQYA 4EIGA 3GHCA 3K47A 3EELA 4XT7A 3FL8A 3RO9A 3I3RA 3HBBA 1DR6A 1U70A 3JSUA 3SRRX 3CLBA 4X5HA 4LEKX 4KLXA 3LG4A 3NRRA 1DR1A 1DYRA 1JOMA 5DFRA 3SAIA 3F0QX 3FY8X 3SRWX 4DPDA 1CZ3A 3NXVA 1RX5A 1RX4A 1RX9A 3KJRA 4I13A 4XT4A 3D84X 2O7PA 1RA3A 2BL9A 3NZCX 3IX9A 3QGTA 4KFJA 1QZFA 4KNEA 4X5FA 2CIGA 3UM6A 1KMSA 3ZPGA 3QL0A 4DDRA 3F0UX 3NZDA 3QG2A 2DRCA 3FRAX 3JWCA 3QLSA 3QL3A 4XT8A 2HQPA 3QFXA 3TQBA 1J3IA 3FY9X 4PSTA 1IA4A 4P3QA 4ELGA 4X5JA 1RX3A 1RA2A 3SRQX 1PDBA 2ANOA 4KJKA 4ELHA 1DR4A 3UM8A 4XT6A 5HT5A 3QLZA 1LY3A 1DDSA 1DAJA 4M6JA 3E0BA 1RA1A 3F91A 4M7VA 3FQ0A 2ANQA 2D5NA 2FZJA 4PSSA 4KM0A 1S3VA 1M78A 4PSYA 5HSRA 4P66A 2P4GA 4QLFA 4HA7A 1DG7A 1DR5A 3CD2A 1HFQA 4X5IA 1AOEA 5CC9A 3I8AX 3QLWA 8DFRA 1J3KA 2BLBA 3FL9A 1DF7A 3F0VX 3KFYA 3FYWX 3GHVA 1DIUA 5ECCA 3JWFA 4DP3A 2BLAA 1DREA 3ROAA 5EAJA 3JW5A 4KY4A 3DRCA 4G3MA 3FYVX 2W3WA 3TD8A 3CL9A 1AO8A 3QYOA 3F0SX 4H95A 3NXRA 5HSUA 5FDAA 1RX2A 4P3RA 4FHBA 1RB3A 3FREX 1DYHA 3VCOA 4KBNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HM9 A;  5JA3 A;  1KMV A;  3R33 A;  1S3W A;  3DL5 A;  4QJC A;  1RB2 A;  3FRB X;  4TU5 X;  2INQ A;  4EIZ A;  4G95 A;  1IA2 A;  2W9H A;  3SA2 A;  2W9S A;  2DHF A;  1OHJ A;  4QLG A;  1DYI A;  3DG8 A;  1RG7 A;  4KD7 A;  3FQC A;  1KLK A;  2C2T A;  2W9T A;  2W3V A;  1LUD A;  5HVB A;  4M7U A;  5HT4 A;  1SEJ A;  3TQ8 A;  1DIS A;  4OSG A;  3KGY A;  2CD2 A;  3NTZ A;  4XEC X;  5HI6 A;  1DYJ A;  4NX7 A;  4KY8 A;  3NXY A;  3DFR A;  1TDR A;  2JYB A;  3DL6 A;  3IRO A;  5DXV A;  1DRA A;  2QK8 A;  4HA9 A;  3S9U A;  1J3J A;  3QLR A;  5HQZ A;  1RX1 A;  2W3M A;  3IRM A;  3NZ6 X;  4PTH A;  2FZH A;  1RD7 A;  2XW7 A;  4KYA A;  5HUI A;  4M6L A;  1RA9 A;  3M08 A;  3SGY A;  1IA1 A;  3JWK A;  1DRF A;  3F8Z A;  4XT5 A;  3FRD X;  4RGC A;  1M79 A;  4KEB A;  4EIL A;  2AZN A;  4IXE D;  3S7A A;  4KJJ A;  3SR5 X;  3JWM A;  3SQY X;  4I1N A;  4Q6A A;  4LAH X;  1RX6 A;  2OBC A;  4Q67 A;  4H98 A;  3FQF A;  4HOF A;  5U27 A;  2OIP A;  1DDR A;  1DR7 A;  4KL9 A;  2B3Z A;  2GD9 A;  4Q0E A;  3QLX A;  3D80 A;  1RH3 A;  3GHW A;  4LAE X;  1AI9 A;  3EEJ A;  1DLS A;  1DHI A;  3QYL A;  2H2Q A;  3TQ9 A;  4EJ1 A;  3TQA A;  3SA1 A;  5CCC A;  1DHF A;  3IA5 A;  4KJL A;  5HF0 X;  3IRN A;  3NZB X;  1DG5 A;  2HXV A;  3K2H A;  3FS6 A;  1DR3 A;  3EEK A;  1BOZ A;  1RX8 A;  2W3A A;  4M6K A;  1DR2 A;  3M09 A;  2D0K A;  4DFR A;  3NU0 A;  4GH8 A;  4OR7 A;  3DAU A;  1PD9 A;  2W9G A;  3NXO A;  3NZ9 X;  1ZDR A;  4QLE A;  3F0B X;  5HF2 X;  4ECK A;  4QHV A;  3K45 A;  3Q1H A;  1E26 A;  1DG8 A;  4ELB A;  2ZZA A;  2FZI A;  4H96 A;  1U71 A;  4KM2 A;  3GI2 A;  1U72 A;  4QJZ D;  3F8Y A;  1DHJ A;  3JTW A;  5ECX A;  3INV A;  4H97 A;  1S3U A;  4PDJ A;  2BLC A;  3NZA X;  2LF1 A;  3F0X X;  3NXT A;  1OHK A;  3SRU X;  2W3B A;  4FGG A;  1D1G A;  3JVX A;  3SH2 A;  1HFP A;  1PD8 A;  2ITH A;  3IA4 A;  3UM5 A;  1MVS A;  1MVT A;  4PTJ A;  1DRB A;  4IXG X;  1HFR A;  3FRF X;  7DFR A;  3ZPC A;  3DAT A;  3L3R A;  4CD2 A;  3CSE A;  1RE7 A;  3EIG A;  1RA8 A;  4LAG X;  4XE6 X;  4ELE A;  4QI9 A;  4NX6 A;  1S3Y A;  4KAK A;  2C2S A;  5JG0 X;  3OAF A;  3FQZ A;  3QLY A;  3RG9 A;  4DPH A;  3FQO A;  4X5G A;  1RX7 A;  4P68 A;  4ELF A;  4HOG A;  4M2X A;  4G8Z X;  4FGH A;  3JW3 A;  3EEM A;  4XRB A;  4Q0D A;  3N0H A;  3NXX A;  4HOE A;  1VDR A;  1IA3 A;  2G6V A;  5HPB A;  1CD2 A;  1LY4 A;  1M7A A;  3OCH A;  1JOL A;  1RF7 A;  5E8Q A;  1JUV A;  6DFR A;  3K74 A;  2L28 A;  3FQV A;  5U26 A;  3KJS A;  1DLR A;  3EX8 A;  1VJ3 A;  3SRS X;  1RC4 A;  3DGA A;  2KGK A;  1BZF A;  3KY8 A;  1YHO A;  3GYF A;  3HJ3 A;  4IXF X;  3S3V A;  1DRH A;  5HVE A;  5HQY A;  4EIG A;  3GHC A;  3K47 A;  3EEL A;  4XT7 A;  3FL8 A;  3RO9 A;  3I3R A;  3HBB A;  1DR6 A;  1U70 A;  3JSU A;  3SRR X;  3CLB A;  4X5H A;  4LEK X;  4KLX A;  3LG4 A;  3NRR A;  1DR1 A;  1DYR A;  1JOM A;  5DFR A;  3SAI A;  3F0Q X;  3FY8 X;  3SRW X;  4DPD A;  1CZ3 A;  3NXV A;  1RX5 A;  1RX4 A;  1RX9 A;  3KJR A;  4I13 A;  4XT4 A;  3D84 X;  2O7P A;  1RA3 A;  2BL9 A;  3NZC X;  3IX9 A;  3QGT A;  4KFJ A;  1QZF A;  4KNE A;  4X5F A;  2CIG A;  3UM6 A;  1KMS A;  3ZPG A;  3QL0 A;  4DDR A;  3F0U X;  3NZD A;  3QG2 A;  2DRC A;  3FRA X;  3JWC A;  3QLS A;  3QL3 A;  4XT8 A;  2HQP A;  3QFX A;  3TQB A;  1J3I A;  3FY9 X;  4PST A;  1IA4 A;  4P3Q A;  4ELG A;  4X5J A;  1RX3 A;  1RA2 A;  3SRQ X;  1PDB A;  2ANO A;  4KJK A;  4ELH A;  1DR4 A;  3UM8 A;  4XT6 A;  5HT5 A;  3QLZ A;  1LY3 A;  1DDS A;  1DAJ A;  4M6J A;  3E0B A;  1RA1 A;  3F91 A;  4M7V A;  3FQ0 A;  2ANQ A;  2D5N A;  2FZJ A;  4PSS A;  4KM0 A;  1S3V A;  1M78 A;  4PSY A;  5HSR A;  4P66 A;  2P4G A;  4QLF A;  4HA7 A;  1DG7 A;  1DR5 A;  3CD2 A;  1HFQ A;  4X5I A;  1AOE A;  5CC9 A;  3I8A X;  3QLW A;  8DFR A;  1J3K A;  2BLB A;  3FL9 A;  1DF7 A;  3F0V X;  3KFY A;  3FYW X;  3GHV A;  1DIU A;  5ECC A;  3JWF A;  4DP3 A;  2BLA A;  1DRE A;  3ROA A;  5EAJ A;  3JW5 A;  4KY4 A;  3DRC A;  4G3M A;  3FYV X;  2W3W A;  3TD8 A;  3CL9 A;  1AO8 A;  3QYO A;  3F0S X;  4H95 A;  3NXR A;  5HSU A;  5FDA A;  1RX2 A;  4P3R A;  4FHB A;  1RB3 A;  3FRE X;  1DYH A;  3VCO A;  4KBN A; 
#chains in the Genus database with same CATH topology
 2HM9 A;  5JA3 A;  1KMV A;  3R33 A;  1S3W A;  3DL5 A;  4QJC A;  1RB2 A;  3FRB X;  4TU5 X;  2INQ A;  4EIZ A;  4G95 A;  1IA2 A;  2W9H A;  3SA2 A;  2W9S A;  2DHF A;  1OHJ A;  4QLG A;  1DYI A;  3DG8 A;  1RG7 A;  4KD7 A;  3FQC A;  1KLK A;  2C2T A;  2W9T A;  2W3V A;  1LUD A;  5HVB A;  4M7U A;  5HT4 A;  1SEJ A;  3TQ8 A;  1DIS A;  4OSG A;  3KGY A;  2CD2 A;  3NTZ A;  4XEC X;  5HI6 A;  1DYJ A;  4NX7 A;  4KY8 A;  3NXY A;  3DFR A;  1TDR A;  2JYB A;  3DL6 A;  3IRO A;  5DXV A;  1DRA A;  2QK8 A;  4HA9 A;  3S9U A;  1J3J A;  3QLR A;  5HQZ A;  1RX1 A;  2W3M A;  3IRM A;  3NZ6 X;  4PTH A;  2FZH A;  1RD7 A;  2XW7 A;  4KYA A;  5HUI A;  4M6L A;  1RA9 A;  3M08 A;  3SGY A;  1IA1 A;  3JWK A;  1DRF A;  3F8Z A;  4XT5 A;  3FRD X;  4RGC A;  1M79 A;  4KEB A;  4EIL A;  2AZN A;  4IXE D;  3S7A A;  4KJJ A;  3SR5 X;  3JWM A;  3SQY X;  4I1N A;  4Q6A A;  4LAH X;  1RX6 A;  2OBC A;  4Q67 A;  4H98 A;  3FQF A;  4HOF A;  5U27 A;  2OIP A;  1DDR A;  1DR7 A;  4KL9 A;  2B3Z A;  2GD9 A;  4Q0E A;  3QLX A;  3D80 A;  1RH3 A;  3GHW A;  4LAE X;  1AI9 A;  3EEJ A;  1DLS A;  1DHI A;  3QYL A;  2H2Q A;  3TQ9 A;  4EJ1 A;  3TQA A;  3SA1 A;  5CCC A;  1DHF A;  3IA5 A;  4KJL A;  5HF0 X;  3IRN A;  3NZB X;  1DG5 A;  2HXV A;  3K2H A;  3FS6 A;  1DR3 A;  3EEK A;  1BOZ A;  1RX8 A;  2W3A A;  4M6K A;  1DR2 A;  3M09 A;  2D0K A;  4DFR A;  3NU0 A;  4GH8 A;  4OR7 A;  3DAU A;  1PD9 A;  2W9G A;  3NXO A;  3NZ9 X;  1ZDR A;  4QLE A;  3F0B X;  5HF2 X;  4ECK A;  4QHV A;  3K45 A;  3Q1H A;  1E26 A;  1DG8 A;  4ELB A;  2ZZA A;  2FZI A;  4H96 A;  1U71 A;  4KM2 A;  3GI2 A;  1U72 A;  4QJZ D;  3F8Y A;  1DHJ A;  3JTW A;  5ECX A;  3INV A;  4H97 A;  1S3U A;  4PDJ A;  2BLC A;  3NZA X;  2LF1 A;  3F0X X;  3NXT A;  1OHK A;  3SRU X;  2W3B A;  4FGG A;  1D1G A;  3JVX A;  3SH2 A;  1HFP A;  1PD8 A;  2ITH A;  3IA4 A;  3UM5 A;  1MVS A;  1MVT A;  4PTJ A;  1DRB A;  4IXG X;  1HFR A;  3FRF X;  7DFR A;  3ZPC A;  3DAT A;  3L3R A;  4CD2 A;  3CSE A;  1RE7 A;  3EIG A;  1RA8 A;  4LAG X;  4XE6 X;  4ELE A;  4QI9 A;  4NX6 A;  1S3Y A;  4KAK A;  2C2S A;  5JG0 X;  3OAF A;  3FQZ A;  3QLY A;  3RG9 A;  4DPH A;  3FQO A;  4X5G A;  1RX7 A;  4P68 A;  4ELF A;  4HOG A;  4M2X A;  4G8Z X;  4FGH A;  3JW3 A;  3EEM A;  4XRB A;  4Q0D A;  3N0H A;  3NXX A;  4HOE A;  1VDR A;  1IA3 A;  2G6V A;  5HPB A;  1CD2 A;  1LY4 A;  1M7A A;  3OCH A;  1JOL A;  1RF7 A;  5E8Q A;  1JUV A;  6DFR A;  3K74 A;  2L28 A;  3FQV A;  5U26 A;  3KJS A;  1DLR A;  3EX8 A;  1VJ3 A;  3SRS X;  1RC4 A;  3DGA A;  2KGK A;  1BZF A;  3KY8 A;  1YHO A;  3GYF A;  3HJ3 A;  4IXF X;  3S3V A;  1DRH A;  5HVE A;  5HQY A;  4EIG A;  3GHC A;  3K47 A;  3EEL A;  4XT7 A;  3FL8 A;  3RO9 A;  3I3R A;  3HBB A;  1DR6 A;  1U70 A;  3JSU A;  3SRR X;  3CLB A;  4X5H A;  4LEK X;  4KLX A;  3LG4 A;  3NRR A;  1DR1 A;  1DYR A;  1JOM A;  5DFR A;  3SAI A;  3F0Q X;  3FY8 X;  3SRW X;  4DPD A;  1CZ3 A;  3NXV A;  1RX5 A;  1RX4 A;  1RX9 A;  3KJR A;  4I13 A;  4XT4 A;  3D84 X;  2O7P A;  1RA3 A;  2BL9 A;  3NZC X;  3IX9 A;  3QGT A;  4KFJ A;  1QZF A;  4KNE A;  4X5F A;  2CIG A;  3UM6 A;  1KMS A;  3ZPG A;  3QL0 A;  4DDR A;  3F0U X;  3NZD A;  3QG2 A;  2DRC A;  3FRA X;  3JWC A;  3QLS A;  3QL3 A;  4XT8 A;  2HQP A;  3QFX A;  3TQB A;  1J3I A;  3FY9 X;  4PST A;  1IA4 A;  4P3Q A;  4ELG A;  4X5J A;  1RX3 A;  1RA2 A;  3SRQ X;  1PDB A;  2ANO A;  4KJK A;  4ELH A;  1DR4 A;  3UM8 A;  4XT6 A;  5HT5 A;  3QLZ A;  1LY3 A;  1DDS A;  1DAJ A;  4M6J A;  3E0B A;  1RA1 A;  3F91 A;  4M7V A;  3FQ0 A;  2ANQ A;  2D5N A;  2FZJ A;  4PSS A;  4KM0 A;  1S3V A;  1M78 A;  4PSY A;  5HSR A;  4P66 A;  2P4G A;  4QLF A;  4HA7 A;  1DG7 A;  1DR5 A;  3CD2 A;  1HFQ A;  4X5I A;  1AOE A;  5CC9 A;  3I8A X;  3QLW A;  8DFR A;  1J3K A;  2BLB A;  3FL9 A;  1DF7 A;  3F0V X;  3KFY A;  3FYW X;  3GHV A;  1DIU A;  5ECC A;  3JWF A;  4DP3 A;  2BLA A;  1DRE A;  3ROA A;  5EAJ A;  3JW5 A;  4KY4 A;  3DRC A;  4G3M A;  3FYV X;  2W3W A;  3TD8 A;  3CL9 A;  1AO8 A;  3QYO A;  3F0S X;  4H95 A;  3NXR A;  5HSU A;  5FDA A;  1RX2 A;  4P3R A;  4FHB A;  1RB3 A;  3FRE X;  1DYH A;  3VCO A;  4KBN A; 
#chains in the Genus database with same CATH homology
 2HM9 A;  5JA3 A;  1KMV A;  3R33 A;  1S3W A;  3DL5 A;  4QJC A;  1RB2 A;  3FRB X;  4TU5 X;  2INQ A;  4EIZ A;  4G95 A;  1IA2 A;  2W9H A;  3SA2 A;  2W9S A;  2DHF A;  1OHJ A;  4QLG A;  1DYI A;  3DG8 A;  1RG7 A;  4KD7 A;  3FQC A;  1KLK A;  2C2T A;  2W9T A;  2W3V A;  1LUD A;  5HVB A;  4M7U A;  5HT4 A;  1SEJ A;  3TQ8 A;  1DIS A;  4OSG A;  3KGY A;  2CD2 A;  3NTZ A;  4XEC X;  5HI6 A;  1DYJ A;  4NX7 A;  4KY8 A;  3NXY A;  3DFR A;  1TDR A;  2JYB A;  3DL6 A;  3IRO A;  5DXV A;  1DRA A;  2QK8 A;  4HA9 A;  3S9U A;  1J3J A;  3QLR A;  5HQZ A;  1RX1 A;  2W3M A;  3IRM A;  3NZ6 X;  4PTH A;  2FZH A;  1RD7 A;  2XW7 A;  4KYA A;  5HUI A;  4M6L A;  1RA9 A;  3M08 A;  3SGY A;  1IA1 A;  3JWK A;  1DRF A;  3F8Z A;  4XT5 A;  3FRD X;  4RGC A;  1M79 A;  4KEB A;  4EIL A;  2AZN A;  4IXE D;  3S7A A;  4KJJ A;  3SR5 X;  3JWM A;  3SQY X;  4I1N A;  4Q6A A;  4LAH X;  1RX6 A;  2OBC A;  4Q67 A;  4H98 A;  3FQF A;  4HOF A;  5U27 A;  2OIP A;  1DDR A;  1DR7 A;  4KL9 A;  2B3Z A;  2GD9 A;  4Q0E A;  3QLX A;  3D80 A;  1RH3 A;  3GHW A;  4LAE X;  1AI9 A;  3EEJ A;  1DLS A;  1DHI A;  3QYL A;  2H2Q A;  3TQ9 A;  4EJ1 A;  3TQA A;  3SA1 A;  5CCC A;  1DHF A;  3IA5 A;  4KJL A;  5HF0 X;  3IRN A;  3NZB X;  1DG5 A;  2HXV A;  3K2H A;  3FS6 A;  1DR3 A;  3EEK A;  1BOZ A;  1RX8 A;  2W3A A;  4M6K A;  1DR2 A;  3M09 A;  2D0K A;  4DFR A;  3NU0 A;  4GH8 A;  4OR7 A;  3DAU A;  1PD9 A;  2W9G A;  3NXO A;  3NZ9 X;  1ZDR A;  4QLE A;  3F0B X;  5HF2 X;  4ECK A;  4QHV A;  3K45 A;  3Q1H A;  1E26 A;  1DG8 A;  4ELB A;  2ZZA A;  2FZI A;  4H96 A;  1U71 A;  4KM2 A;  3GI2 A;  1U72 A;  4QJZ D;  3F8Y A;  1DHJ A;  3JTW A;  5ECX A;  3INV A;  4H97 A;  1S3U A;  4PDJ A;  2BLC A;  3NZA X;  2LF1 A;  3F0X X;  3NXT A;  1OHK A;  3SRU X;  2W3B A;  4FGG A;  1D1G A;  3JVX A;  3SH2 A;  1HFP A;  1PD8 A;  2ITH A;  3IA4 A;  3UM5 A;  1MVS A;  1MVT A;  4PTJ A;  1DRB A;  4IXG X;  1HFR A;  3FRF X;  7DFR A;  3ZPC A;  3DAT A;  3L3R A;  4CD2 A;  3CSE A;  1RE7 A;  3EIG A;  1RA8 A;  4LAG X;  4XE6 X;  4ELE A;  4QI9 A;  4NX6 A;  1S3Y A;  4KAK A;  2C2S A;  5JG0 X;  3OAF A;  3FQZ A;  3QLY A;  3RG9 A;  4DPH A;  3FQO A;  4X5G A;  1RX7 A;  4P68 A;  4ELF A;  4HOG A;  4M2X A;  4G8Z X;  4FGH A;  3JW3 A;  3EEM A;  4XRB A;  4Q0D A;  3N0H A;  3NXX A;  4HOE A;  1VDR A;  1IA3 A;  2G6V A;  5HPB A;  1CD2 A;  1LY4 A;  1M7A A;  3OCH A;  1JOL A;  1RF7 A;  5E8Q A;  1JUV A;  6DFR A;  3K74 A;  2L28 A;  3FQV A;  5U26 A;  3KJS A;  1DLR A;  3EX8 A;  1VJ3 A;  3SRS X;  1RC4 A;  3DGA A;  2KGK A;  1BZF A;  3KY8 A;  1YHO A;  3GYF A;  3HJ3 A;  4IXF X;  3S3V A;  1DRH A;  5HVE A;  5HQY A;  4EIG A;  3GHC A;  3K47 A;  3EEL A;  4XT7 A;  3FL8 A;  3RO9 A;  3I3R A;  3HBB A;  1DR6 A;  1U70 A;  3JSU A;  3SRR X;  3CLB A;  4X5H A;  4LEK X;  4KLX A;  3LG4 A;  3NRR A;  1DR1 A;  1DYR A;  1JOM A;  5DFR A;  3SAI A;  3F0Q X;  3FY8 X;  3SRW X;  4DPD A;  1CZ3 A;  3NXV A;  1RX5 A;  1RX4 A;  1RX9 A;  3KJR A;  4I13 A;  4XT4 A;  3D84 X;  2O7P A;  1RA3 A;  2BL9 A;  3NZC X;  3IX9 A;  3QGT A;  4KFJ A;  1QZF A;  4KNE A;  4X5F A;  2CIG A;  3UM6 A;  1KMS A;  3ZPG A;  3QL0 A;  4DDR A;  3F0U X;  3NZD A;  3QG2 A;  2DRC A;  3FRA X;  3JWC A;  3QLS A;  3QL3 A;  4XT8 A;  2HQP A;  3QFX A;  3TQB A;  1J3I A;  3FY9 X;  4PST A;  1IA4 A;  4P3Q A;  4ELG A;  4X5J A;  1RX3 A;  1RA2 A;  3SRQ X;  1PDB A;  2ANO A;  4KJK A;  4ELH A;  1DR4 A;  3UM8 A;  4XT6 A;  5HT5 A;  3QLZ A;  1LY3 A;  1DDS A;  1DAJ A;  4M6J A;  3E0B A;  1RA1 A;  3F91 A;  4M7V A;  3FQ0 A;  2ANQ A;  2D5N A;  2FZJ A;  4PSS A;  4KM0 A;  1S3V A;  1M78 A;  4PSY A;  5HSR A;  4P66 A;  2P4G A;  4QLF A;  4HA7 A;  1DG7 A;  1DR5 A;  3CD2 A;  1HFQ A;  4X5I A;  1AOE A;  5CC9 A;  3I8A X;  3QLW A;  8DFR A;  1J3K A;  2BLB A;  3FL9 A;  1DF7 A;  3F0V X;  3KFY A;  3FYW X;  3GHV A;  1DIU A;  5ECC A;  3JWF A;  4DP3 A;  2BLA A;  1DRE A;  3ROA A;  5EAJ A;  3JW5 A;  4KY4 A;  3DRC A;  4G3M A;  3FYV X;  2W3W A;  3TD8 A;  3CL9 A;  1AO8 A;  3QYO A;  3F0S X;  4H95 A;  3NXR A;  5HSU A;  5FDA A;  1RX2 A;  4P3R A;  4FHB A;  1RB3 A;  3FRE X;  1DYH A;  3VCO A;  4KBN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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