1GQ7A

Proclavaminate amidino hydrolase from streptomyces clavuligerus
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
Knots found
sequence length
301
structure length
301
Chain Sequence
SPRYAQIPTFMRLPHDPQPRGYDVVVIGAPYDGGTSYRPGARFGPQAIRSESGLIHGVGIDRGPGTFDLINCVDAGDINLTPFDMNIAIDTAQSHLSGLLKANAAFLMIGGDHSLTVAALRAVAEQHGPLAVVHLDAHSDTNPAFYGGRYHHGTPFRHGIDEKLIDPAAMVQIGIRGHNPKPDSLDYARGHGVRVVTADEFGELGVGGTADLIREKVGQRPVYVSVDIDVVDPAFAPGTGTPAPGGLLSREVLALLRCVGDLKPVGFDVMEVSPLYDHGGITSILATEIGAELLYQYARAH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Streptomyces clavuligerus
molecule keywords PROCLAVAMINATE AMIDINO HYDROLASE
total genus 106
structure length 301
sequence length 301
chains with identical sequence B, C, D, E, F
other databases KnotProt 2.0: S +31 +31 +31
ec nomenclature ec 3.5.3.22: Proclavaminate amidinohydrolase.
pdb deposition date 2001-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1gq7A00
1HQFA 3GN0A 4GSVA 3E8QA 1TBJA 4RHJA 3MFVA 1T4SA 2EF5A 3MFWA 4MYFA 1RLAA 3SJTA 1ZPGA 4FCIA 1P8RA 1GQ6A 1T5FA 1TBLA 4Q40A 2PLLA 4RHLA 4MYKA 4Q3SA 2EF4A 3THJA 1TBHA 4DZ4A 4Q3UA 1P8PA 2EIVA 4IU5A 3MMRA 1PQ3A 3NIPA 3NIOA 1T4PA 1WOIA 1P8QA 5RLAA 3SL1A 3F80A 1T5GA 4MYLA 4RLAA 4MXRA 4G3HA 1WVAA 4IE1A 1D3VA 4IE2A 4RHKA 4GSMA 4Q3RC 1HQXA 3MJLA 4IXVA 2PHAA 2ZAVA 3CEVA 4RHMA 3PZLA 4HXQA 3NIQA 3E8ZA 1TA1A 4Q3RA 4Q42A 1T4RA 4MYNA 1WVBA 4Q3QA 3SKKA 4GWCA 4IU1A 1HQGA 2PHOA 3GMZA 1R1OA 4IXUA 5HJAA 4Q3VA 4Q3PA 1P8OA 1HQHA 2RLAA 4HZEA 4RHIA 4IU0A 3KV2A 3THHA 4CEVA 3E6KA 4GSZA 3DJ8A 3M1RA 4GWDA 4RHQA 5HJ9A 3THEA 1CEVA 3E9BA 4Q41A 1GQ7A 3TH7A 4IE3A 3LP7A 4IU4A 5CEVA 1XFKA 4ITYA 4FCKA 1P8SA 3LP4A 2A0MA 1P8MA 3RLAA 3E6VA 3SL0A 1P8NA 1WOGA 1ZPEA 3LHLA 2CEVA 3TF3A 4HWWA 2AEBA 4Q3TA 1HQ5A 4I06A 1WOHA 1T4TA
chains in the Genus database with same CATH superfamily
3C0YA 1HQFA 5EEKA 3EZTA 3GN0A 4GSVA 3EWFA 3F07A 3E8QA 1ZZ1A 2V5XA 5EFKB 4ZURA 3RQDA 1TBJA 4RHJA 1T64A 3MFVA 1T4SA 2EF5A 3MFWA 3Q9FA 3C10A 5THSA 3MENA 5EFNA 5EFJD 4BZ5A 4MYFA 4ZUMA 1RLAA 2VQWG 3EZPA 3SJTA 5EFBD 4QA6A 4RN1A 5G1BA 1ZPGA 5THTA 4QA2A 5LI3A 1ZZ0A 3MZ3A 4FCIA 1P8RA 1GQ6A 5EF8A 1T5FA 1TBLA 3SL1A 4Q40A 3ZNSA 2PLLA 4RHLA 5EFGA 4MYKA 4Q3SA 2EF4A 1T67A 4QA5A 1TBHA 5G0XA 3THJA 4DZ4A 4Q3UA 1P8PA 5EF7A 1C3RA 2EIVA 4IU5A 3MMRA 2V5WA 5G12A 1PQ3A 3Q9CA 3EW8A 3NIOA 1T4PA 1WOIA 1P8QA 3NIPA 5DC7A 5EEIA 5G11A 5G17A 5RLAA 2GH6A 3F80A 3MZ6A 1T5GA 4LXZA 3F0RA 3F06A 5IWGA 1C3PA 2VQJA 4MYLA 4RLAA 1WOHA 4MXRA 4RN0A 5FUEA 4G3HA 1WVAA 5EEFA 4BZ7A 4IE1A 5IX0A 1D3VA 4IE2A 4BZ8A 4RHKA 4QA1A 4GSMA 2VQVA 4Q3RC 3SKKA 1HQXA 3Q9BA 5G0JA 3MJLA 5THVA 5THUA 1VKGA 5FCWA 4IXVA 2PHAA 2ZAVA 3CEVA 4RHMA 3PZLA 4HXQA 3NIQA 3E8ZA 1TA1A 4Q3RA 4Q42A 1T4RA 4MYNA 1WVBA 4Q3QA 5D1CA 4QA0A 5EFHA 4GWCA 4IU1A 5G13A 1HQGA 2PHOA 4CBTA 4ZUQA 4RN2A 3GMZA 5DC5A 1R1OA 1T69A 5G1CA 4IXUA 4ZUOA 5HJAA 4Q3VA 5G0YA 4A69A 4Q3PA 4QA4A 1P8OA 1HQHA 5G1AA 2RLAA 4HZEA 4RHIA 4IU0A 3MAXA 3KV2A 5ICNB 3THHA 4CQFA 4CEVA 5G3WA 3E6KA 4GSZA 4QA7A 3SFHA 3DJ8A 2VQMA 3M1RA 4GWDA 4RHQA 5EENA 1ZZ3A 5G10A 5HJ9A 3THEA 2VQQA 1CEVA 3E9BA 4QA3A 3SFFA 3C0ZA 4BZ6A 4Q41A 1GQ7A 3TH7A 5G0GA 4IE3A 3LP7A 4IU4A 5DC6A 5BWZA 5CEVA 3ZNRA 1XFKA 3MZ4A 4ITYA 4FCKA 5G0HA 1P8SA 2VQOA 2A0MA 3LP4A 1C3SA 1P8MA 1W22A 3RLAA 3E6VA 5DC8A 3SL0A 4CBYA 4ZUPA 5D1DA 1P8NA 1WOGA 1ZPEA 4BKXB 3LHLA 5JI5A 5D1BA 3MZ7A 5G0IA 2CEVA 3Q9EA 5EEMA 4LY1A 3TF3A 4ZUNA 4BZ9A 5A2SA 4HWWA 2AEBA 4Q3TA 1HQ5A 4I06A 2VCGA 1T4TA
chains in the Genus database with same CATH topology
1HQFA 3GN0A 4GSVA 3E8QA 1TBJA 4RHJA 3MFVA 1T4SA 2EF5A 3MFWA 4MYFA 1RLAA 3SJTA 1ZPGA 4FCIA 1P8RA 1GQ6A 1T5FA 1TBLA 4Q40A 2PLLA 4RHLA 4MYKA 4Q3SA 2EF4A 3THJA 1TBHA 4DZ4A 4Q3UA 1P8PA 2EIVA 4IU5A 3MMRA 1PQ3A 3NIPA 3NIOA 1T4PA 1WOIA 1P8QA 5RLAA 3SL1A 3F80A 1T5GA 4MYLA 4RLAA 4MXRA 4G3HA 1WVAA 4IE1A 1D3VA 4IE2A 4RHKA 4GSMA 4Q3RC 1HQXA 3MJLA 4IXVA 2PHAA 2ZAVA 3CEVA 4RHMA 3PZLA 4HXQA 3NIQA 3E8ZA 1TA1A 4Q3RA 4Q42A 1T4RA 4MYNA 1WVBA 4Q3QA 3SKKA 4GWCA 4IU1A 1HQGA 2PHOA 3GMZA 1R1OA 4IXUA 5HJAA 4Q3VA 4Q3PA 1P8OA 1HQHA 2RLAA 4HZEA 4RHIA 4IU0A 3KV2A 3THHA 4CEVA 3E6KA 4GSZA 3DJ8A 3M1RA 4GWDA 4RHQA 5HJ9A 3THEA 1CEVA 3E9BA 4Q41A 1GQ7A 3TH7A 4IE3A 3LP7A 4IU4A 5CEVA 1XFKA 4ITYA 4FCKA 1P8SA 3LP4A 2A0MA 1P8MA 3RLAA 3E6VA 3SL0A 1P8NA 1WOGA 1ZPEA 3LHLA 2CEVA 3TF3A 4HWWA 2AEBA 4Q3TA 1HQ5A 4I06A 1WOHA 1T4TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HQF A;  3GN0 A;  4GSV A;  3E8Q A;  1TBJ A;  4RHJ A;  3MFV A;  1T4S A;  2EF5 A;  3MFW A;  4MYF A;  1RLA A;  3SJT A;  1ZPG A;  4FCI A;  1P8R A;  1GQ6 A;  1T5F A;  1TBL A;  4Q40 A;  2PLL A;  4RHL A;  4MYK A;  4Q3S A;  2EF4 A;  3THJ A;  1TBH A;  4DZ4 A;  4Q3U A;  1P8P A;  2EIV A;  4IU5 A;  3MMR A;  1PQ3 A;  3NIP A;  3NIO A;  1T4P A;  1WOI A;  1P8Q A;  5RLA A;  3SL1 A;  3F80 A;  1T5G A;  4MYL A;  4RLA A;  4MXR A;  4G3H A;  1WVA A;  4IE1 A;  1D3V A;  4IE2 A;  4RHK A;  4GSM A;  4Q3R C;  1HQX A;  3MJL A;  4IXV A;  2PHA A;  2ZAV A;  3CEV A;  4RHM A;  3PZL A;  4HXQ A;  3NIQ A;  3E8Z A;  1TA1 A;  4Q3R A;  4Q42 A;  1T4R A;  4MYN A;  1WVB A;  4Q3Q A;  3SKK A;  4GWC A;  4IU1 A;  1HQG A;  2PHO A;  3GMZ A;  1R1O A;  4IXU A;  5HJA A;  4Q3V A;  4Q3P A;  1P8O A;  1HQH A;  2RLA A;  4HZE A;  4RHI A;  4IU0 A;  3KV2 A;  3THH A;  4CEV A;  3E6K A;  4GSZ A;  3DJ8 A;  3M1R A;  4GWD A;  4RHQ A;  5HJ9 A;  3THE A;  1CEV A;  3E9B A;  4Q41 A;  1GQ7 A;  3TH7 A;  4IE3 A;  3LP7 A;  4IU4 A;  5CEV A;  1XFK A;  4ITY A;  4FCK A;  1P8S A;  3LP4 A;  2A0M A;  1P8M A;  3RLA A;  3E6V A;  3SL0 A;  1P8N A;  1WOG A;  1ZPE A;  3LHL A;  2CEV A;  3TF3 A;  4HWW A;  2AEB A;  4Q3T A;  1HQ5 A;  4I06 A;  1WOH A;  1T4T A; 
#chains in the Genus database with same CATH topology
 3C0Y A;  1HQF A;  5EEK A;  3EZT A;  3GN0 A;  4GSV A;  3EWF A;  3F07 A;  3E8Q A;  1ZZ1 A;  2V5X A;  5EFK B;  4ZUR A;  3RQD A;  1TBJ A;  4RHJ A;  1T64 A;  3MFV A;  1T4S A;  2EF5 A;  3MFW A;  3Q9F A;  3C10 A;  5THS A;  3MEN A;  5EFN A;  5EFJ D;  4BZ5 A;  4MYF A;  4ZUM A;  1RLA A;  2VQW G;  3EZP A;  3SJT A;  5EFB D;  4QA6 A;  4RN1 A;  5G1B A;  1ZPG A;  5THT A;  4QA2 A;  5LI3 A;  1ZZ0 A;  3MZ3 A;  4FCI A;  1P8R A;  1GQ6 A;  5EF8 A;  1T5F A;  1TBL A;  3SL1 A;  4Q40 A;  3ZNS A;  2PLL A;  4RHL A;  5EFG A;  4MYK A;  4Q3S A;  2EF4 A;  1T67 A;  4QA5 A;  1TBH A;  5G0X A;  3THJ A;  4DZ4 A;  4Q3U A;  1P8P A;  5EF7 A;  1C3R A;  2EIV A;  4IU5 A;  3MMR A;  2V5W A;  5G12 A;  1PQ3 A;  3Q9C A;  3EW8 A;  3NIO A;  1T4P A;  1WOI A;  1P8Q A;  3NIP A;  5DC7 A;  5EEI A;  5G11 A;  5G17 A;  5RLA A;  2GH6 A;  3F80 A;  3MZ6 A;  1T5G A;  4LXZ A;  3F0R A;  3F06 A;  5IWG A;  1C3P A;  2VQJ A;  4MYL A;  4RLA A;  1WOH A;  4MXR A;  4RN0 A;  5FUE A;  4G3H A;  1WVA A;  5EEF A;  4BZ7 A;  4IE1 A;  5IX0 A;  1D3V A;  4IE2 A;  4BZ8 A;  4RHK A;  4QA1 A;  4GSM A;  2VQV A;  4Q3R C;  3SKK A;  1HQX A;  3Q9B A;  5G0J A;  3MJL A;  5THV A;  5THU A;  1VKG A;  5FCW A;  4IXV A;  2PHA A;  2ZAV A;  3CEV A;  4RHM A;  3PZL A;  4HXQ A;  3NIQ A;  3E8Z A;  1TA1 A;  4Q3R A;  4Q42 A;  1T4R A;  4MYN A;  1WVB A;  4Q3Q A;  5D1C A;  4QA0 A;  5EFH A;  4GWC A;  4IU1 A;  5G13 A;  1HQG A;  2PHO A;  4CBT A;  4ZUQ A;  4RN2 A;  3GMZ A;  5DC5 A;  1R1O A;  1T69 A;  5G1C A;  4IXU A;  4ZUO A;  5HJA A;  4Q3V A;  5G0Y A;  4A69 A;  4Q3P A;  4QA4 A;  1P8O A;  1HQH A;  5G1A A;  2RLA A;  4HZE A;  4RHI A;  4IU0 A;  3MAX A;  3KV2 A;  5ICN B;  3THH A;  4CQF A;  4CEV A;  5G3W A;  3E6K A;  4GSZ A;  4QA7 A;  3SFH A;  3DJ8 A;  2VQM A;  3M1R A;  4GWD A;  4RHQ A;  5EEN A;  1ZZ3 A;  5G10 A;  5HJ9 A;  3THE A;  2VQQ A;  1CEV A;  3E9B A;  4QA3 A;  3SFF A;  3C0Z A;  4BZ6 A;  4Q41 A;  1GQ7 A;  3TH7 A;  5G0G A;  4IE3 A;  3LP7 A;  4IU4 A;  5DC6 A;  5BWZ A;  5CEV A;  3ZNR A;  1XFK A;  3MZ4 A;  4ITY A;  4FCK A;  5G0H A;  1P8S A;  2VQO A;  2A0M A;  3LP4 A;  1C3S A;  1P8M A;  1W22 A;  3RLA A;  3E6V A;  5DC8 A;  3SL0 A;  4CBY A;  4ZUP A;  5D1D A;  1P8N A;  1WOG A;  1ZPE A;  4BKX B;  3LHL A;  5JI5 A;  5D1B A;  3MZ7 A;  5G0I A;  2CEV A;  3Q9E A;  5EEM A;  4LY1 A;  3TF3 A;  4ZUN A;  4BZ9 A;  5A2S A;  4HWW A;  2AEB A;  4Q3T A;  1HQ5 A;  4I06 A;  2VCG A;  1T4T A; 
#chains in the Genus database with same CATH homology
 1HQF A;  3GN0 A;  4GSV A;  3E8Q A;  1TBJ A;  4RHJ A;  3MFV A;  1T4S A;  2EF5 A;  3MFW A;  4MYF A;  1RLA A;  3SJT A;  1ZPG A;  4FCI A;  1P8R A;  1GQ6 A;  1T5F A;  1TBL A;  4Q40 A;  2PLL A;  4RHL A;  4MYK A;  4Q3S A;  2EF4 A;  3THJ A;  1TBH A;  4DZ4 A;  4Q3U A;  1P8P A;  2EIV A;  4IU5 A;  3MMR A;  1PQ3 A;  3NIP A;  3NIO A;  1T4P A;  1WOI A;  1P8Q A;  5RLA A;  3SL1 A;  3F80 A;  1T5G A;  4MYL A;  4RLA A;  4MXR A;  4G3H A;  1WVA A;  4IE1 A;  1D3V A;  4IE2 A;  4RHK A;  4GSM A;  4Q3R C;  1HQX A;  3MJL A;  4IXV A;  2PHA A;  2ZAV A;  3CEV A;  4RHM A;  3PZL A;  4HXQ A;  3NIQ A;  3E8Z A;  1TA1 A;  4Q3R A;  4Q42 A;  1T4R A;  4MYN A;  1WVB A;  4Q3Q A;  3SKK A;  4GWC A;  4IU1 A;  1HQG A;  2PHO A;  3GMZ A;  1R1O A;  4IXU A;  5HJA A;  4Q3V A;  4Q3P A;  1P8O A;  1HQH A;  2RLA A;  4HZE A;  4RHI A;  4IU0 A;  3KV2 A;  3THH A;  4CEV A;  3E6K A;  4GSZ A;  3DJ8 A;  3M1R A;  4GWD A;  4RHQ A;  5HJ9 A;  3THE A;  1CEV A;  3E9B A;  4Q41 A;  1GQ7 A;  3TH7 A;  4IE3 A;  3LP7 A;  4IU4 A;  5CEV A;  1XFK A;  4ITY A;  4FCK A;  1P8S A;  3LP4 A;  2A0M A;  1P8M A;  3RLA A;  3E6V A;  3SL0 A;  1P8N A;  1WOG A;  1ZPE A;  3LHL A;  2CEV A;  3TF3 A;  4HWW A;  2AEB A;  4Q3T A;  1HQ5 A;  4I06 A;  1WOH A;  1T4T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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