1WOGA

Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
Knots found
sequence length
303
structure length
303
Chain Sequence
GPAHLPYGGIPTFARAPLVQPDGDWQADVAALGVPFDIALGFRPGARFAPRALREASLRSVPPFTGLDGKTRLQGVTFADAGDVILPSLEPQLAHDRITEAARQVRGRCRVPVFLGGDHSVSYPLLRAFADVPDLHVVQLDAHLDFTDTRNDTKWSNSSPFRRACEALPNLVHITTVGLRGLRFDPEAVAAARARGHTIIPMDDVTADLAGVLAQLPRGQNVYFSVDVDGFDPAVIPGTSSPEPDGLTYAQGMKILAAAAANNTVVGLDLVELAPNLDPTGRSELLMARLVMETLCEVFDHVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
pubmed doi rcsb
molecule tags Hydrolase
source organism Deinococcus radiodurans
molecule keywords agmatinase
total genus 114
structure length 303
sequence length 303
chains with identical sequence B, C, D, E, F
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.5.3.11: Agmatinase.
pdb deposition date 2004-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1wogA00
3THHA 1P8NA 3CEVA 4MXRA 1RLAA 3TH7A 4DZ4A 1ZPGA 2ZAVA 3LP7A 1T4RA 4MYNA 1T4TA 4RLAA 2EF4A 1TA1A 4FCKA 4Q3TA 1GQ6A 3NIQA 4MYKA 5CEVA 1WOGA 4Q3SA 4G3HA 1WVAA 3SJTA 4Q3RC 1P8RA 1ZPEA 4Q3RA 3MFWA 3E6KA 4HZEA 4Q40A 1P8PA 4HXQA 4RHIA 2AEBA 4IE3A 1TBHA 3LP4A 4RHMA 4HWWA 4Q3UA 1TBLA 4RHLA 3PZLA 4IE1A 4RHJA 3THEA 1T5FA 1D3VA 2EIVA 2PLLA 3GMZA 4RHKA 3NIPA 3F80A 1TBJA 3E9BA 2PHOA 1HQHA 1PQ3A 4Q3PA 3E6VA 3TF3A 1HQGA 3E8QA 1XFKA 2CEVA 4GSMA 1T4PA 3SL0A 3MJLA 4FCIA 4ITYA 1WOHA 1P8QA 4IXVA 1WVBA 5RLAA 3RLAA 4GSZA 4Q42A 4Q3QA 3DJ8A 1T5GA 4Q41A 1HQXA 4Q3VA 1P8MA 2PHAA 4GWDA 3E8ZA 3MMRA 4IU1A 3NIOA 3MFVA 2A0MA 3SKKA 4IXUA 3SL1A 4I06A 4MYLA 1CEVA 1P8OA 3LHLA 3KV2A 4MYFA 4GSVA 1GQ7A 3THJA 5HJAA 4GWCA 3GN0A 1R1OA 4IU4A 2RLAA 4CEVA 4IU5A 4IU0A 2EF5A 4RHQA 1HQFA 1P8SA 3M1RA 5HJ9A 1T4SA 4IE2A 1WOIA 1HQ5A
chains in the Genus database with same CATH superfamily
5G17A 3THHA 1C3SA 1T64A 1P8NA 4QA5A 3CEVA 1C3PA 3C10A 4MXRA 5EEIA 1RLAA 3MZ4A 5EEMA 3EW8A 3TH7A 3ZNRA 4DZ4A 1ZPGA 4ZUMA 2ZAVA 3Q9EA 3LP7A 1T4RA 2VQQA 4RN1A 3SFHA 4MYNA 5G0XA 5THTA 1ZZ1A 1T4TA 4QA4A 4RLAA 2VQJA 3ZNSA 2EF4A 1TA1A 4FCKA 4QA2A 4Q3TA 5EFNA 3Q9FA 1GQ6A 3NIQA 4MYKA 5CEVA 3Q9BA 1WOGA 5DC5A 4Q3SA 4CQFA 4G3HA 5D1CA 3SFFA 2VQVA 3F06A 1WVAA 5G0GA 3SJTA 3MENA 4Q3RC 1P8RA 1ZPEA 4Q3RA 3MFWA 3E6KA 4HZEA 4Q40A 5G11A 1P8PA 4HXQA 5EFHA 5IX0A 3MAXA 4RHIA 5EEFA 1C3RA 4BZ8A 2VQMA 5EFBD 2AEBA 4IE3A 1VKGA 1TBHA 3LP4A 4RHMA 4HWWA 4Q3UA 5FCWA 1TBLA 5G0JA 1T67A 4RHLA 3PZLA 4IE1A 4RHJA 3THEA 3C0YA 4LY1A 4BZ7A 4QA6A 5EF7A 5G10A 4ZUNA 1T5FA 1D3VA 2EIVA 2PLLA 3GMZA 4RHKA 3EWFA 3MZ6A 1ZZ3A 3EZPA 3NIPA 5G0IA 3F80A 5EF8A 1TBJA 3E9BA 5EFKB 5THSA 4QA7A 2PHOA 1HQHA 1PQ3A 4Q3PA 4BZ6A 3E6VA 4CBYA 3TF3A 4BKXB 1HQGA 3E8QA 2VQOA 2V5WA 1XFKA 2CEVA 4GSMA 1T4PA 5IWGA 3SL0A 4RN2A 3MJLA 4FCIA 4ITYA 1WOHA 5EENA 1P8QA 4IXVA 5G1CA 2VCGA 1WVBA 5RLAA 3RLAA 4GSZA 4Q42A 5ICNB 4Q3QA 5D1DA 3DJ8A 1T5GA 1ZZ0A 1T69A 4Q41A 1HQXA 3F0RA 5G1BA 4Q3VA 2GH6A 1P8MA 2PHAA 4GWDA 3E8ZA 3MMRA 4IU1A 4QA3A 5G0HA 4BZ9A 5D1BA 5DC7A 5EEKA 3MFVA 3NIOA 5G12A 2A0MA 3Q9CA 3SKKA 4BZ5A 4IXUA 3SL1A 4I06A 4MYLA 1CEVA 3MZ7A 5DC6A 4ZUQA 5G3WA 4A69A 1P8OA 3LHLA 4QA0A 5DC8A 4ZUOA 4ZURA 3KV2A 4LXZA 4MYFA 5LI3A 4GSVA 1GQ7A 3C0ZA 3THJA 5JI5A 5HJAA 4GWCA 3GN0A 5G0YA 4CBTA 4QA1A 5THVA 1W22A 1R1OA 4IU4A 5EFGA 2RLAA 5G1AA 4IU5A 4CEVA 3EZTA 4IU0A 5G13A 2EF5A 2V5XA 4RHQA 1HQFA 5FUEA 5THUA 5BWZA 3RQDA 5A2SA 1P8SA 3M1RA 4RN0A 5EFJD 2VQWG 1T4SA 5HJ9A 4IE2A 1WOIA 1HQ5A 3MZ3A 4ZUPA 3F07A
chains in the Genus database with same CATH topology
3THHA 1P8NA 3CEVA 4MXRA 1RLAA 3TH7A 4DZ4A 1ZPGA 2ZAVA 3LP7A 1T4RA 4MYNA 1T4TA 4RLAA 2EF4A 1TA1A 4FCKA 4Q3TA 1GQ6A 3NIQA 4MYKA 5CEVA 1WOGA 4Q3SA 4G3HA 1WVAA 3SJTA 4Q3RC 1P8RA 1ZPEA 4Q3RA 3MFWA 3E6KA 4HZEA 4Q40A 1P8PA 4HXQA 4RHIA 2AEBA 4IE3A 1TBHA 3LP4A 4RHMA 4HWWA 4Q3UA 1TBLA 4RHLA 3PZLA 4IE1A 4RHJA 3THEA 1T5FA 1D3VA 2EIVA 2PLLA 3GMZA 4RHKA 3NIPA 3F80A 1TBJA 3E9BA 2PHOA 1HQHA 1PQ3A 4Q3PA 3E6VA 3TF3A 1HQGA 3E8QA 1XFKA 2CEVA 4GSMA 1T4PA 3SL0A 3MJLA 4FCIA 4ITYA 1WOHA 1P8QA 4IXVA 1WVBA 5RLAA 3RLAA 4GSZA 4Q42A 4Q3QA 3DJ8A 1T5GA 4Q41A 1HQXA 4Q3VA 1P8MA 2PHAA 4GWDA 3E8ZA 3MMRA 4IU1A 3NIOA 3MFVA 2A0MA 3SKKA 4IXUA 3SL1A 4I06A 4MYLA 1CEVA 1P8OA 3LHLA 3KV2A 4MYFA 4GSVA 1GQ7A 3THJA 5HJAA 4GWCA 3GN0A 1R1OA 4IU4A 2RLAA 4CEVA 4IU5A 4IU0A 2EF5A 4RHQA 1HQFA 1P8SA 3M1RA 5HJ9A 1T4SA 4IE2A 1WOIA 1HQ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3THH A;  1P8N A;  3CEV A;  4MXR A;  1RLA A;  3TH7 A;  4DZ4 A;  1ZPG A;  2ZAV A;  3LP7 A;  1T4R A;  4MYN A;  1T4T A;  4RLA A;  2EF4 A;  1TA1 A;  4FCK A;  4Q3T A;  1GQ6 A;  3NIQ A;  4MYK A;  5CEV A;  1WOG A;  4Q3S A;  4G3H A;  1WVA A;  3SJT A;  4Q3R C;  1P8R A;  1ZPE A;  4Q3R A;  3MFW A;  3E6K A;  4HZE A;  4Q40 A;  1P8P A;  4HXQ A;  4RHI A;  2AEB A;  4IE3 A;  1TBH A;  3LP4 A;  4RHM A;  4HWW A;  4Q3U A;  1TBL A;  4RHL A;  3PZL A;  4IE1 A;  4RHJ A;  3THE A;  1T5F A;  1D3V A;  2EIV A;  2PLL A;  3GMZ A;  4RHK A;  3NIP A;  3F80 A;  1TBJ A;  3E9B A;  2PHO A;  1HQH A;  1PQ3 A;  4Q3P A;  3E6V A;  3TF3 A;  1HQG A;  3E8Q A;  1XFK A;  2CEV A;  4GSM A;  1T4P A;  3SL0 A;  3MJL A;  4FCI A;  4ITY A;  1WOH A;  1P8Q A;  4IXV A;  1WVB A;  5RLA A;  3RLA A;  4GSZ A;  4Q42 A;  4Q3Q A;  3DJ8 A;  1T5G A;  4Q41 A;  1HQX A;  4Q3V A;  1P8M A;  2PHA A;  4GWD A;  3E8Z A;  3MMR A;  4IU1 A;  3NIO A;  3MFV A;  2A0M A;  3SKK A;  4IXU A;  3SL1 A;  4I06 A;  4MYL A;  1CEV A;  1P8O A;  3LHL A;  3KV2 A;  4MYF A;  4GSV A;  1GQ7 A;  3THJ A;  5HJA A;  4GWC A;  3GN0 A;  1R1O A;  4IU4 A;  2RLA A;  4CEV A;  4IU5 A;  4IU0 A;  2EF5 A;  4RHQ A;  1HQF A;  1P8S A;  3M1R A;  5HJ9 A;  1T4S A;  4IE2 A;  1WOI A;  1HQ5 A; 
#chains in the Genus database with same CATH topology
 5G17 A;  3THH A;  1C3S A;  1T64 A;  1P8N A;  4QA5 A;  3CEV A;  1C3P A;  3C10 A;  4MXR A;  5EEI A;  1RLA A;  3MZ4 A;  5EEM A;  3EW8 A;  3TH7 A;  3ZNR A;  4DZ4 A;  1ZPG A;  4ZUM A;  2ZAV A;  3Q9E A;  3LP7 A;  1T4R A;  2VQQ A;  4RN1 A;  3SFH A;  4MYN A;  5G0X A;  5THT A;  1ZZ1 A;  1T4T A;  4QA4 A;  4RLA A;  2VQJ A;  3ZNS A;  2EF4 A;  1TA1 A;  4FCK A;  4QA2 A;  4Q3T A;  5EFN A;  3Q9F A;  1GQ6 A;  3NIQ A;  4MYK A;  5CEV A;  3Q9B A;  1WOG A;  5DC5 A;  4Q3S A;  4CQF A;  4G3H A;  5D1C A;  3SFF A;  2VQV A;  3F06 A;  1WVA A;  5G0G A;  3SJT A;  3MEN A;  4Q3R C;  1P8R A;  1ZPE A;  4Q3R A;  3MFW A;  3E6K A;  4HZE A;  4Q40 A;  5G11 A;  1P8P A;  4HXQ A;  5EFH A;  5IX0 A;  3MAX A;  4RHI A;  5EEF A;  1C3R A;  4BZ8 A;  2VQM A;  5EFB D;  2AEB A;  4IE3 A;  1VKG A;  1TBH A;  3LP4 A;  4RHM A;  4HWW A;  4Q3U A;  5FCW A;  1TBL A;  5G0J A;  1T67 A;  4RHL A;  3PZL A;  4IE1 A;  4RHJ A;  3THE A;  3C0Y A;  4LY1 A;  4BZ7 A;  4QA6 A;  5EF7 A;  5G10 A;  4ZUN A;  1T5F A;  1D3V A;  2EIV A;  2PLL A;  3GMZ A;  4RHK A;  3EWF A;  3MZ6 A;  1ZZ3 A;  3EZP A;  3NIP A;  5G0I A;  3F80 A;  5EF8 A;  1TBJ A;  3E9B A;  5EFK B;  5THS A;  4QA7 A;  2PHO A;  1HQH A;  1PQ3 A;  4Q3P A;  4BZ6 A;  3E6V A;  4CBY A;  3TF3 A;  4BKX B;  1HQG A;  3E8Q A;  2VQO A;  2V5W A;  1XFK A;  2CEV A;  4GSM A;  1T4P A;  5IWG A;  3SL0 A;  4RN2 A;  3MJL A;  4FCI A;  4ITY A;  1WOH A;  5EEN A;  1P8Q A;  4IXV A;  5G1C A;  2VCG A;  1WVB A;  5RLA A;  3RLA A;  4GSZ A;  4Q42 A;  5ICN B;  4Q3Q A;  5D1D A;  3DJ8 A;  1T5G A;  1ZZ0 A;  1T69 A;  4Q41 A;  1HQX A;  3F0R A;  5G1B A;  4Q3V A;  2GH6 A;  1P8M A;  2PHA A;  4GWD A;  3E8Z A;  3MMR A;  4IU1 A;  4QA3 A;  5G0H A;  4BZ9 A;  5D1B A;  5DC7 A;  5EEK A;  3MFV A;  3NIO A;  5G12 A;  2A0M A;  3Q9C A;  3SKK A;  4BZ5 A;  4IXU A;  3SL1 A;  4I06 A;  4MYL A;  1CEV A;  3MZ7 A;  5DC6 A;  4ZUQ A;  5G3W A;  4A69 A;  1P8O A;  3LHL A;  4QA0 A;  5DC8 A;  4ZUO A;  4ZUR A;  3KV2 A;  4LXZ A;  4MYF A;  5LI3 A;  4GSV A;  1GQ7 A;  3C0Z A;  3THJ A;  5JI5 A;  5HJA A;  4GWC A;  3GN0 A;  5G0Y A;  4CBT A;  4QA1 A;  5THV A;  1W22 A;  1R1O A;  4IU4 A;  5EFG A;  2RLA A;  5G1A A;  4IU5 A;  4CEV A;  3EZT A;  4IU0 A;  5G13 A;  2EF5 A;  2V5X A;  4RHQ A;  1HQF A;  5FUE A;  5THU A;  5BWZ A;  3RQD A;  5A2S A;  1P8S A;  3M1R A;  4RN0 A;  5EFJ D;  2VQW G;  1T4S A;  5HJ9 A;  4IE2 A;  1WOI A;  1HQ5 A;  3MZ3 A;  4ZUP A;  3F07 A; 
#chains in the Genus database with same CATH homology
 3THH A;  1P8N A;  3CEV A;  4MXR A;  1RLA A;  3TH7 A;  4DZ4 A;  1ZPG A;  2ZAV A;  3LP7 A;  1T4R A;  4MYN A;  1T4T A;  4RLA A;  2EF4 A;  1TA1 A;  4FCK A;  4Q3T A;  1GQ6 A;  3NIQ A;  4MYK A;  5CEV A;  1WOG A;  4Q3S A;  4G3H A;  1WVA A;  3SJT A;  4Q3R C;  1P8R A;  1ZPE A;  4Q3R A;  3MFW A;  3E6K A;  4HZE A;  4Q40 A;  1P8P A;  4HXQ A;  4RHI A;  2AEB A;  4IE3 A;  1TBH A;  3LP4 A;  4RHM A;  4HWW A;  4Q3U A;  1TBL A;  4RHL A;  3PZL A;  4IE1 A;  4RHJ A;  3THE A;  1T5F A;  1D3V A;  2EIV A;  2PLL A;  3GMZ A;  4RHK A;  3NIP A;  3F80 A;  1TBJ A;  3E9B A;  2PHO A;  1HQH A;  1PQ3 A;  4Q3P A;  3E6V A;  3TF3 A;  1HQG A;  3E8Q A;  1XFK A;  2CEV A;  4GSM A;  1T4P A;  3SL0 A;  3MJL A;  4FCI A;  4ITY A;  1WOH A;  1P8Q A;  4IXV A;  1WVB A;  5RLA A;  3RLA A;  4GSZ A;  4Q42 A;  4Q3Q A;  3DJ8 A;  1T5G A;  4Q41 A;  1HQX A;  4Q3V A;  1P8M A;  2PHA A;  4GWD A;  3E8Z A;  3MMR A;  4IU1 A;  3NIO A;  3MFV A;  2A0M A;  3SKK A;  4IXU A;  3SL1 A;  4I06 A;  4MYL A;  1CEV A;  1P8O A;  3LHL A;  3KV2 A;  4MYF A;  4GSV A;  1GQ7 A;  3THJ A;  5HJA A;  4GWC A;  3GN0 A;  1R1O A;  4IU4 A;  2RLA A;  4CEV A;  4IU5 A;  4IU0 A;  2EF5 A;  4RHQ A;  1HQF A;  1P8S A;  3M1R A;  5HJ9 A;  1T4S A;  4IE2 A;  1WOI A;  1HQ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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