1WOHA

Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
Knots found
sequence length
303
structure length
303
Chain Sequence
GPAHLPYGGIPTFARAPLVQPDGDWQADVAALGVPFDIALGFRPGARFAPRALREASLRSVPPFTGLDGKTRLQGVTFADAGDVILPSLEPQLAHDRITEAARQVRGRCRVPVFLGGDHSVSYPLLRAFADVPDLHVVQLDAHLDFTDTRNDTKWSNSSPFRRACEALPNLVHITTVGLRGLRFDPEAVAAARARGHTIIPMDDVTADLAGVLAQLPRGQNVYFSVDVDGFDPAVIPGTSSPEPDGLTYAQGMKILAAAAANNTVVGLDLVELAPNLDPTGRSELLMARLVMETLCEVFDHVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
pubmed doi rcsb
molecule tags Hydrolase
source organism Deinococcus radiodurans
molecule keywords agmatinase
total genus 114
structure length 303
sequence length 303
chains with identical sequence B, C, D, E, F
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.5.3.11: Agmatinase.
pdb deposition date 2004-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1wohA00
1TBHA 1RLAA 4IE1A 1GQ6A 4Q3QA 5HJ9A 1HQFA 4IU5A 4CEVA 1TBLA 2PLLA 4GSMA 3GMZA 1T5GA 4MYLA 4RHKA 3E9BA 1HQXA 2EF5A 1WOGA 1HQHA 3M1RA 3LHLA 3PZLA 4Q40A 4GWCA 1HQGA 3TF3A 1P8OA 4Q3PA 3SKKA 2PHOA 3SL1A 5HJAA 4RHJA 2A0MA 3LP4A 4FCKA 3E6KA 4IE3A 1T4TA 3DJ8A 2RLAA 4HZEA 3THHA 4RHIA 3F80A 4Q42A 4IU4A 1P8PA 3E8QA 4Q41A 4RHMA 5CEVA 4IU1A 1WOHA 4HXQA 4GSZA 2EIVA 3NIOA 4Q3UA 1T4RA 2AEBA 4Q3RC 3TH7A 2CEVA 3NIPA 4HWWA 1T4PA 3E8ZA 1CEVA 1P8NA 4IXVA 3MMRA 1P8QA 1P8RA 1P8MA 3SJTA 3E6VA 1ZPGA 1PQ3A 4GSVA 4MYNA 1R1OA 1WOIA 4MYFA 1TA1A 1TBJA 1T4SA 3THJA 4I06A 1WVAA 3CEVA 4IXUA 3MFWA 1D3VA 2ZAVA 1P8SA 1GQ7A 5RLAA 4MXRA 1WVBA 3RLAA 1ZPEA 3LP7A 2EF4A 3GN0A 4RHQA 3MFVA 3THEA 4RLAA 1T5FA 4G3HA 1HQ5A 4ITYA 4IE2A 2PHAA 4Q3TA 3KV2A 4Q3SA 4Q3RA 4DZ4A 3MJLA 4GWDA 4FCIA 4IU0A 1XFKA 4Q3VA 4RHLA 3NIQA 3SL0A 4MYKA
chains in the Genus database with same CATH superfamily
5FUEA 1TBHA 1C3RA 1ZZ1A 1RLAA 4IE1A 1GQ6A 2VCGA 4Q3QA 5HJ9A 1HQFA 4IU5A 5DC8A 4CEVA 5EEMA 1TBLA 2PLLA 1VKGA 4ZUMA 3MAXA 4LXZA 5THUA 4GSMA 4QA5A 3GMZA 1T5GA 5G0HA 4MYLA 3F07A 3E9BA 4RHKA 4RN0A 5D1BA 1HQXA 5EF7A 5G13A 2EF5A 1WOGA 4ZUQA 3Q9EA 1HQHA 3M1RA 5EFNA 4BZ6A 3LHLA 4A69A 3PZLA 3MZ7A 5THSA 2VQOA 5G1CA 4Q40A 5ICNB 2V5XA 4CQFA 5G12A 4GWCA 1HQGA 3TF3A 1C3PA 1P8OA 5EFBD 4LY1A 4Q3PA 5THTA 2PHOA 3SKKA 5LI3A 5EFGA 4BZ8A 3SL1A 5G17A 5HJAA 2VQMA 4QA0A 5EENA 4RHJA 4CBYA 5G0YA 5EEKA 2A0MA 5EFJD 4BZ9A 5BWZA 2VQJA 3LP4A 1C3SA 4FCKA 3E6KA 4ZURA 4IE3A 1T4TA 3DJ8A 4QA7A 2RLAA 4HZEA 5THVA 3THHA 4RHIA 3F80A 3MZ3A 4Q42A 5G0IA 4BZ5A 5A2SA 4ZUOA 5IX0A 4IU4A 1P8PA 1T69A 3E8QA 4Q41A 4RHMA 5CEVA 4IU1A 1WOHA 5JI5A 3Q9FA 4HXQA 4GSZA 5IWGA 1ZZ0A 2EIVA 3NIOA 3Q9BA 3MENA 5EFKB 4Q3UA 1T4RA 2AEBA 4Q3RC 3TH7A 2CEVA 3NIPA 4HWWA 4ZUNA 5EEFA 1T4PA 3C10A 3E8ZA 3RQDA 4CBTA 5G1BA 1CEVA 1P8NA 4IXVA 3MMRA 1P8QA 1P8RA 1T64A 3EZPA 1P8MA 5DC6A 4QA6A 3SFHA 3SJTA 5D1CA 3E6VA 2VQQA 1ZPGA 1PQ3A 3MZ6A 4GSVA 4MYNA 5FCWA 3ZNSA 1R1OA 5EEIA 1ZZ3A 5G1AA 3MZ4A 1WOIA 3EZTA 4MYFA 5G0JA 5DC5A 1TA1A 1TBJA 5G3WA 1T4SA 3THJA 5G11A 4ZUPA 4QA2A 5G10A 4I06A 5D1DA 1WVAA 3CEVA 4IXUA 3C0YA 3MFWA 4RN1A 3F0RA 1D3VA 2ZAVA 1P8SA 4QA1A 4BKXB 1GQ7A 3F06A 5RLAA 2VQVA 3C0ZA 4MXRA 1WVBA 3SFFA 3RLAA 1ZPEA 3LP7A 2EF4A 3GN0A 4RHQA 3MFVA 5DC7A 5G0GA 3THEA 4RLAA 1T5FA 4G3HA 2VQWG 4QA4A 1HQ5A 4ITYA 4IE2A 2PHAA 4Q3TA 3KV2A 4Q3SA 4Q3RA 4DZ4A 3MJLA 4GWDA 1W22A 4FCIA 2V5WA 1XFKA 2GH6A 4IU0A 4Q3VA 4RN2A 4RHLA 5EF8A 1T67A 3Q9CA 5G0XA 4QA3A 3NIQA 3SL0A 3ZNRA 4MYKA 3EW8A 5EFHA 3EWFA 4BZ7A
chains in the Genus database with same CATH topology
1TBHA 1RLAA 4IE1A 1GQ6A 4Q3QA 5HJ9A 1HQFA 4IU5A 4CEVA 1TBLA 2PLLA 4GSMA 3GMZA 1T5GA 4MYLA 4RHKA 3E9BA 1HQXA 2EF5A 1WOGA 1HQHA 3M1RA 3LHLA 3PZLA 4Q40A 4GWCA 1HQGA 3TF3A 1P8OA 4Q3PA 3SKKA 2PHOA 3SL1A 5HJAA 4RHJA 2A0MA 3LP4A 4FCKA 3E6KA 4IE3A 1T4TA 3DJ8A 2RLAA 4HZEA 3THHA 4RHIA 3F80A 4Q42A 4IU4A 1P8PA 3E8QA 4Q41A 4RHMA 5CEVA 4IU1A 1WOHA 4HXQA 4GSZA 2EIVA 3NIOA 4Q3UA 1T4RA 2AEBA 4Q3RC 3TH7A 2CEVA 3NIPA 4HWWA 1T4PA 3E8ZA 1CEVA 1P8NA 4IXVA 3MMRA 1P8QA 1P8RA 1P8MA 3SJTA 3E6VA 1ZPGA 1PQ3A 4GSVA 4MYNA 1R1OA 1WOIA 4MYFA 1TA1A 1TBJA 1T4SA 3THJA 4I06A 1WVAA 3CEVA 4IXUA 3MFWA 1D3VA 2ZAVA 1P8SA 1GQ7A 5RLAA 4MXRA 1WVBA 3RLAA 1ZPEA 3LP7A 2EF4A 3GN0A 4RHQA 3MFVA 3THEA 4RLAA 1T5FA 4G3HA 1HQ5A 4ITYA 4IE2A 2PHAA 4Q3TA 3KV2A 4Q3SA 4Q3RA 4DZ4A 3MJLA 4GWDA 4FCIA 4IU0A 1XFKA 4Q3VA 4RHLA 3NIQA 3SL0A 4MYKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TBH A;  1RLA A;  4IE1 A;  1GQ6 A;  4Q3Q A;  5HJ9 A;  1HQF A;  4IU5 A;  4CEV A;  1TBL A;  2PLL A;  4GSM A;  3GMZ A;  1T5G A;  4MYL A;  4RHK A;  3E9B A;  1HQX A;  2EF5 A;  1WOG A;  1HQH A;  3M1R A;  3LHL A;  3PZL A;  4Q40 A;  4GWC A;  1HQG A;  3TF3 A;  1P8O A;  4Q3P A;  3SKK A;  2PHO A;  3SL1 A;  5HJA A;  4RHJ A;  2A0M A;  3LP4 A;  4FCK A;  3E6K A;  4IE3 A;  1T4T A;  3DJ8 A;  2RLA A;  4HZE A;  3THH A;  4RHI A;  3F80 A;  4Q42 A;  4IU4 A;  1P8P A;  3E8Q A;  4Q41 A;  4RHM A;  5CEV A;  4IU1 A;  1WOH A;  4HXQ A;  4GSZ A;  2EIV A;  3NIO A;  4Q3U A;  1T4R A;  2AEB A;  4Q3R C;  3TH7 A;  2CEV A;  3NIP A;  4HWW A;  1T4P A;  3E8Z A;  1CEV A;  1P8N A;  4IXV A;  3MMR A;  1P8Q A;  1P8R A;  1P8M A;  3SJT A;  3E6V A;  1ZPG A;  1PQ3 A;  4GSV A;  4MYN A;  1R1O A;  1WOI A;  4MYF A;  1TA1 A;  1TBJ A;  1T4S A;  3THJ A;  4I06 A;  1WVA A;  3CEV A;  4IXU A;  3MFW A;  1D3V A;  2ZAV A;  1P8S A;  1GQ7 A;  5RLA A;  4MXR A;  1WVB A;  3RLA A;  1ZPE A;  3LP7 A;  2EF4 A;  3GN0 A;  4RHQ A;  3MFV A;  3THE A;  4RLA A;  1T5F A;  4G3H A;  1HQ5 A;  4ITY A;  4IE2 A;  2PHA A;  4Q3T A;  3KV2 A;  4Q3S A;  4Q3R A;  4DZ4 A;  3MJL A;  4GWD A;  4FCI A;  4IU0 A;  1XFK A;  4Q3V A;  4RHL A;  3NIQ A;  3SL0 A;  4MYK A; 
#chains in the Genus database with same CATH topology
 5FUE A;  1TBH A;  1C3R A;  1ZZ1 A;  1RLA A;  4IE1 A;  1GQ6 A;  2VCG A;  4Q3Q A;  5HJ9 A;  1HQF A;  4IU5 A;  5DC8 A;  4CEV A;  5EEM A;  1TBL A;  2PLL A;  1VKG A;  4ZUM A;  3MAX A;  4LXZ A;  5THU A;  4GSM A;  4QA5 A;  3GMZ A;  1T5G A;  5G0H A;  4MYL A;  3F07 A;  3E9B A;  4RHK A;  4RN0 A;  5D1B A;  1HQX A;  5EF7 A;  5G13 A;  2EF5 A;  1WOG A;  4ZUQ A;  3Q9E A;  1HQH A;  3M1R A;  5EFN A;  4BZ6 A;  3LHL A;  4A69 A;  3PZL A;  3MZ7 A;  5THS A;  2VQO A;  5G1C A;  4Q40 A;  5ICN B;  2V5X A;  4CQF A;  5G12 A;  4GWC A;  1HQG A;  3TF3 A;  1C3P A;  1P8O A;  5EFB D;  4LY1 A;  4Q3P A;  5THT A;  2PHO A;  3SKK A;  5LI3 A;  5EFG A;  4BZ8 A;  3SL1 A;  5G17 A;  5HJA A;  2VQM A;  4QA0 A;  5EEN A;  4RHJ A;  4CBY A;  5G0Y A;  5EEK A;  2A0M A;  5EFJ D;  4BZ9 A;  5BWZ A;  2VQJ A;  3LP4 A;  1C3S A;  4FCK A;  3E6K A;  4ZUR A;  4IE3 A;  1T4T A;  3DJ8 A;  4QA7 A;  2RLA A;  4HZE A;  5THV A;  3THH A;  4RHI A;  3F80 A;  3MZ3 A;  4Q42 A;  5G0I A;  4BZ5 A;  5A2S A;  4ZUO A;  5IX0 A;  4IU4 A;  1P8P A;  1T69 A;  3E8Q A;  4Q41 A;  4RHM A;  5CEV A;  4IU1 A;  1WOH A;  5JI5 A;  3Q9F A;  4HXQ A;  4GSZ A;  5IWG A;  1ZZ0 A;  2EIV A;  3NIO A;  3Q9B A;  3MEN A;  5EFK B;  4Q3U A;  1T4R A;  2AEB A;  4Q3R C;  3TH7 A;  2CEV A;  3NIP A;  4HWW A;  4ZUN A;  5EEF A;  1T4P A;  3C10 A;  3E8Z A;  3RQD A;  4CBT A;  5G1B A;  1CEV A;  1P8N A;  4IXV A;  3MMR A;  1P8Q A;  1P8R A;  1T64 A;  3EZP A;  1P8M A;  5DC6 A;  4QA6 A;  3SFH A;  3SJT A;  5D1C A;  3E6V A;  2VQQ A;  1ZPG A;  1PQ3 A;  3MZ6 A;  4GSV A;  4MYN A;  5FCW A;  3ZNS A;  1R1O A;  5EEI A;  1ZZ3 A;  5G1A A;  3MZ4 A;  1WOI A;  3EZT A;  4MYF A;  5G0J A;  5DC5 A;  1TA1 A;  1TBJ A;  5G3W A;  1T4S A;  3THJ A;  5G11 A;  4ZUP A;  4QA2 A;  5G10 A;  4I06 A;  5D1D A;  1WVA A;  3CEV A;  4IXU A;  3C0Y A;  3MFW A;  4RN1 A;  3F0R A;  1D3V A;  2ZAV A;  1P8S A;  4QA1 A;  4BKX B;  1GQ7 A;  3F06 A;  5RLA A;  2VQV A;  3C0Z A;  4MXR A;  1WVB A;  3SFF A;  3RLA A;  1ZPE A;  3LP7 A;  2EF4 A;  3GN0 A;  4RHQ A;  3MFV A;  5DC7 A;  5G0G A;  3THE A;  4RLA A;  1T5F A;  4G3H A;  2VQW G;  4QA4 A;  1HQ5 A;  4ITY A;  4IE2 A;  2PHA A;  4Q3T A;  3KV2 A;  4Q3S A;  4Q3R A;  4DZ4 A;  3MJL A;  4GWD A;  1W22 A;  4FCI A;  2V5W A;  1XFK A;  2GH6 A;  4IU0 A;  4Q3V A;  4RN2 A;  4RHL A;  5EF8 A;  1T67 A;  3Q9C A;  5G0X A;  4QA3 A;  3NIQ A;  3SL0 A;  3ZNR A;  4MYK A;  3EW8 A;  5EFH A;  3EWF A;  4BZ7 A; 
#chains in the Genus database with same CATH homology
 1TBH A;  1RLA A;  4IE1 A;  1GQ6 A;  4Q3Q A;  5HJ9 A;  1HQF A;  4IU5 A;  4CEV A;  1TBL A;  2PLL A;  4GSM A;  3GMZ A;  1T5G A;  4MYL A;  4RHK A;  3E9B A;  1HQX A;  2EF5 A;  1WOG A;  1HQH A;  3M1R A;  3LHL A;  3PZL A;  4Q40 A;  4GWC A;  1HQG A;  3TF3 A;  1P8O A;  4Q3P A;  3SKK A;  2PHO A;  3SL1 A;  5HJA A;  4RHJ A;  2A0M A;  3LP4 A;  4FCK A;  3E6K A;  4IE3 A;  1T4T A;  3DJ8 A;  2RLA A;  4HZE A;  3THH A;  4RHI A;  3F80 A;  4Q42 A;  4IU4 A;  1P8P A;  3E8Q A;  4Q41 A;  4RHM A;  5CEV A;  4IU1 A;  1WOH A;  4HXQ A;  4GSZ A;  2EIV A;  3NIO A;  4Q3U A;  1T4R A;  2AEB A;  4Q3R C;  3TH7 A;  2CEV A;  3NIP A;  4HWW A;  1T4P A;  3E8Z A;  1CEV A;  1P8N A;  4IXV A;  3MMR A;  1P8Q A;  1P8R A;  1P8M A;  3SJT A;  3E6V A;  1ZPG A;  1PQ3 A;  4GSV A;  4MYN A;  1R1O A;  1WOI A;  4MYF A;  1TA1 A;  1TBJ A;  1T4S A;  3THJ A;  4I06 A;  1WVA A;  3CEV A;  4IXU A;  3MFW A;  1D3V A;  2ZAV A;  1P8S A;  1GQ7 A;  5RLA A;  4MXR A;  1WVB A;  3RLA A;  1ZPE A;  3LP7 A;  2EF4 A;  3GN0 A;  4RHQ A;  3MFV A;  3THE A;  4RLA A;  1T5F A;  4G3H A;  1HQ5 A;  4ITY A;  4IE2 A;  2PHA A;  4Q3T A;  3KV2 A;  4Q3S A;  4Q3R A;  4DZ4 A;  3MJL A;  4GWD A;  4FCI A;  4IU0 A;  1XFK A;  4Q3V A;  4RHL A;  3NIQ A;  3SL0 A;  4MYK A; 
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similar chains in the Genus database (?% sequence similarity)
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