1WOHA

Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
Knots found
sequence length
303
structure length
303
Chain Sequence
GPAHLPYGGIPTFARAPLVQPDGDWQADVAALGVPFDIALGFRPGARFAPRALREASLRSVPPFTGLDGKTRLQGVTFADAGDVILPSLEPQLAHDRITEAARQVRGRCRVPVFLGGDHSVSYPLLRAFADVPDLHVVQLDAHLDFTDTRNDTKWSNSSPFRRACEALPNLVHITTVGLRGLRFDPEAVAAARARGHTIIPMDDVTADLAGVLAQLPRGQNVYFSVDVDGFDPAVIPGTSSPEPDGLTYAQGMKILAAAAANNTVVGLDLVELAPNLDPTGRSELLMARLVMETLCEVFDHVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
pubmed doi rcsb
molecule tags Hydrolase
source organism Deinococcus radiodurans
molecule keywords agmatinase
total genus 114
structure length 303
sequence length 303
chains with identical sequence B, C, D, E, F
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.5.3.11: Agmatinase.
pdb deposition date 2004-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1wohA00
3DJ8A 4IXVA 4RHIA 1PQ3A 1P8OA 4RHQA 1TBLA 3PZLA 1ZPGA 4RHKA 1TA1A 4HWWA 4Q3UA 1P8QA 4GWCA 1P8SA 1T4RA 3RLAA 4Q3VA 1RLAA 3NIQA 4Q3SA 3M1RA 1P8PA 2EF4A 4Q42A 2EIVA 4GSMA 3E8ZA 1R1OA 2PHOA 4MYLA 3SL1A 3KV2A 4I06A 2PLLA 1TBJA 4ITYA 3GMZA 3MFVA 2PHAA 3THEA 3GN0A 4IU5A 3E8QA 5CEVA 1WVAA 3MMRA 4Q3RC 3NIPA 1T4TA 4Q3QA 1HQXA 3F80A 1WVBA 3SKKA 4IU1A 1D3VA 4FCKA 4DZ4A 1T5GA 2CEVA 4MXRA 4MYFA 4GSZA 4HXQA 4Q3TA 2RLAA 4RHLA 4IE1A 4RHMA 1P8NA 4IU4A 1P8MA 1WOHA 4MYKA 5RLAA 4GSVA 1TBHA 1P8RA 1WOGA 3NIOA 4G3HA 3LP7A 3SJTA 2ZAVA 3MFWA 1ZPEA 3THJA 3THHA 1WOIA 1GQ7A 4MYNA 1T5FA 1HQFA 1XFKA 4IU0A 5HJAA 3E6KA 4Q3PA 3LP4A 4IE2A 4Q40A 4Q41A 2EF5A 4IE3A 3E9BA 3MJLA 4GWDA 5HJ9A 1HQHA 4FCIA 4RHJA 1GQ6A 4HZEA 4RLAA 2AEBA 1HQGA 4IXUA 1HQ5A 3LHLA 4CEVA 3TH7A 1CEVA 1T4SA 3TF3A 3SL0A 1T4PA 3CEVA 3E6VA 4Q3RA 2A0MA
chains in the Genus database with same CATH superfamily
5DC7A 3DJ8A 4IXVA 4RHIA 1PQ3A 1P8OA 4RHQA 4CBYA 3F06A 4LY1A 1TBLA 3PZLA 1ZPGA 5EEMA 4RHKA 1TA1A 4HWWA 4Q3UA 1P8QA 5G0XA 5G1AA 4GWCA 1P8SA 1T4RA 5EFNA 4BZ9A 1ZZ3A 5G17A 3RLAA 4Q3VA 4QA1A 3Q9FA 1RLAA 3NIQA 4Q3SA 5G11A 3Q9BA 3Q9CA 5D1DA 3ZNRA 4ZUMA 3M1RA 2VQMA 1P8PA 2VQVA 5DC8A 2EF4A 5EF7A 3EW8A 4Q42A 2VQQA 3EWFA 5EENA 4ZUQA 2EIVA 4GSMA 3E8ZA 2VQJA 5G0YA 5LI3A 1R1OA 2PHOA 3EZPA 3C0ZA 5G0JA 4MYLA 3C0YA 5G0HA 3SL1A 3KV2A 1C3PA 4I06A 5THSA 4CBTA 5EFKB 2PLLA 2VQWG 1TBJA 5IX0A 4ITYA 4RN2A 3GMZA 5EEKA 2VCGA 3MFVA 2PHAA 4BZ8A 4CQFA 3THEA 1ZZ0A 3GN0A 4IU5A 3E8QA 5CEVA 3F0RA 5EFJD 1WVAA 3MMRA 4Q3RC 4QA4A 3NIPA 1T4TA 5DC5A 4Q3QA 1HQXA 3F80A 1WVBA 3SKKA 2VQOA 4IU1A 5DC6A 4QA6A 4QA7A 1D3VA 4FCKA 5G12A 2V5XA 5D1CA 4DZ4A 3ZNSA 5BWZA 4BKXB 5EF8A 1T67A 1T5GA 4QA2A 5G3WA 2CEVA 1C3SA 4MXRA 4MYFA 4GSZA 3Q9EA 4HXQA 4Q3TA 5D1BA 2RLAA 4RHLA 4IE1A 4RHMA 1P8NA 4IU4A 4ZUOA 1P8MA 1WOHA 4MYKA 5RLAA 4RN1A 3RQDA 4Q3RA 4QA3A 4GSVA 5G0GA 3MZ3A 3SFFA 3MZ4A 1TBHA 4ZUNA 1P8RA 1C3RA 1WOGA 5JI5A 4RN0A 3NIOA 4G3HA 5G0IA 5THTA 5THVA 3LP7A 3SJTA 2ZAVA 4BZ7A 3MFWA 1ZPEA 3EZTA 3MAXA 3THHA 1WOIA 3THJA 4A69A 4BZ5A 5G1CA 1GQ7A 4MYNA 1ZZ1A 1T5FA 5EEFA 1HQFA 1T69A 3SFHA 1XFKA 5IWGA 4QA0A 4IU0A 4ZURA 3F07A 2V5WA 3MENA 4LXZA 5FUEA 5FCWA 3E6KA 5HJAA 4Q3PA 3LP4A 4IE2A 4Q40A 4Q41A 2EF5A 5A2SA 4IE3A 5EFHA 3E9BA 4BZ6A 3MJLA 1VKGA 3C10A 4GWDA 5HJ9A 3MZ7A 5EFGA 5G1BA 1HQHA 4FCIA 4RHJA 1GQ6A 4HZEA 4RLAA 4ZUPA 5ICNB 2AEBA 1HQGA 4IXUA 5EEIA 5G10A 1HQ5A 4QA5A 5G13A 3LHLA 4CEVA 3TH7A 1T64A 1CEVA 1T4SA 3MZ6A 3TF3A 1W22A 3SL0A 5THUA 1T4PA 2GH6A 3CEVA 3E6VA 5EFBD 2A0MA
chains in the Genus database with same CATH topology
3DJ8A 4IXVA 4RHIA 1PQ3A 1P8OA 4RHQA 1TBLA 3PZLA 1ZPGA 4RHKA 1TA1A 4HWWA 4Q3UA 1P8QA 4GWCA 1P8SA 1T4RA 3RLAA 4Q3VA 1RLAA 3NIQA 4Q3SA 3M1RA 1P8PA 2EF4A 4Q42A 2EIVA 4GSMA 3E8ZA 1R1OA 2PHOA 4MYLA 3SL1A 3KV2A 4I06A 2PLLA 1TBJA 4ITYA 3GMZA 3MFVA 2PHAA 3THEA 3GN0A 4IU5A 3E8QA 5CEVA 1WVAA 3MMRA 4Q3RC 3NIPA 1T4TA 4Q3QA 1HQXA 3F80A 1WVBA 3SKKA 4IU1A 1D3VA 4FCKA 4DZ4A 1T5GA 2CEVA 4MXRA 4MYFA 4GSZA 4HXQA 4Q3TA 2RLAA 4RHLA 4IE1A 4RHMA 1P8NA 4IU4A 1P8MA 1WOHA 4MYKA 5RLAA 4GSVA 1TBHA 1P8RA 1WOGA 3NIOA 4G3HA 3LP7A 3SJTA 2ZAVA 3MFWA 1ZPEA 3THJA 3THHA 1WOIA 1GQ7A 4MYNA 1T5FA 1HQFA 1XFKA 4IU0A 5HJAA 3E6KA 4Q3PA 3LP4A 4IE2A 4Q40A 4Q41A 2EF5A 4IE3A 3E9BA 3MJLA 4GWDA 5HJ9A 1HQHA 4FCIA 4RHJA 1GQ6A 4HZEA 4RLAA 2AEBA 1HQGA 4IXUA 1HQ5A 3LHLA 4CEVA 3TH7A 1CEVA 1T4SA 3TF3A 3SL0A 1T4PA 3CEVA 3E6VA 4Q3RA 2A0MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DJ8 A;  4IXV A;  4RHI A;  1PQ3 A;  1P8O A;  4RHQ A;  1TBL A;  3PZL A;  1ZPG A;  4RHK A;  1TA1 A;  4HWW A;  4Q3U A;  1P8Q A;  4GWC A;  1P8S A;  1T4R A;  3RLA A;  4Q3V A;  1RLA A;  3NIQ A;  4Q3S A;  3M1R A;  1P8P A;  2EF4 A;  4Q42 A;  2EIV A;  4GSM A;  3E8Z A;  1R1O A;  2PHO A;  4MYL A;  3SL1 A;  3KV2 A;  4I06 A;  2PLL A;  1TBJ A;  4ITY A;  3GMZ A;  3MFV A;  2PHA A;  3THE A;  3GN0 A;  4IU5 A;  3E8Q A;  5CEV A;  1WVA A;  3MMR A;  4Q3R C;  3NIP A;  1T4T A;  4Q3Q A;  1HQX A;  3F80 A;  1WVB A;  3SKK A;  4IU1 A;  1D3V A;  4FCK A;  4DZ4 A;  1T5G A;  2CEV A;  4MXR A;  4MYF A;  4GSZ A;  4HXQ A;  4Q3T A;  2RLA A;  4RHL A;  4IE1 A;  4RHM A;  1P8N A;  4IU4 A;  1P8M A;  1WOH A;  4MYK A;  5RLA A;  4GSV A;  1TBH A;  1P8R A;  1WOG A;  3NIO A;  4G3H A;  3LP7 A;  3SJT A;  2ZAV A;  3MFW A;  1ZPE A;  3THJ A;  3THH A;  1WOI A;  1GQ7 A;  4MYN A;  1T5F A;  1HQF A;  1XFK A;  4IU0 A;  5HJA A;  3E6K A;  4Q3P A;  3LP4 A;  4IE2 A;  4Q40 A;  4Q41 A;  2EF5 A;  4IE3 A;  3E9B A;  3MJL A;  4GWD A;  5HJ9 A;  1HQH A;  4FCI A;  4RHJ A;  1GQ6 A;  4HZE A;  4RLA A;  2AEB A;  1HQG A;  4IXU A;  1HQ5 A;  3LHL A;  4CEV A;  3TH7 A;  1CEV A;  1T4S A;  3TF3 A;  3SL0 A;  1T4P A;  3CEV A;  3E6V A;  4Q3R A;  2A0M A; 
#chains in the Genus database with same CATH topology
 5DC7 A;  3DJ8 A;  4IXV A;  4RHI A;  1PQ3 A;  1P8O A;  4RHQ A;  4CBY A;  3F06 A;  4LY1 A;  1TBL A;  3PZL A;  1ZPG A;  5EEM A;  4RHK A;  1TA1 A;  4HWW A;  4Q3U A;  1P8Q A;  5G0X A;  5G1A A;  4GWC A;  1P8S A;  1T4R A;  5EFN A;  4BZ9 A;  1ZZ3 A;  5G17 A;  3RLA A;  4Q3V A;  4QA1 A;  3Q9F A;  1RLA A;  3NIQ A;  4Q3S A;  5G11 A;  3Q9B A;  3Q9C A;  5D1D A;  3ZNR A;  4ZUM A;  3M1R A;  2VQM A;  1P8P A;  2VQV A;  5DC8 A;  2EF4 A;  5EF7 A;  3EW8 A;  4Q42 A;  2VQQ A;  3EWF A;  5EEN A;  4ZUQ A;  2EIV A;  4GSM A;  3E8Z A;  2VQJ A;  5G0Y A;  5LI3 A;  1R1O A;  2PHO A;  3EZP A;  3C0Z A;  5G0J A;  4MYL A;  3C0Y A;  5G0H A;  3SL1 A;  3KV2 A;  1C3P A;  4I06 A;  5THS A;  4CBT A;  5EFK B;  2PLL A;  2VQW G;  1TBJ A;  5IX0 A;  4ITY A;  4RN2 A;  3GMZ A;  5EEK A;  2VCG A;  3MFV A;  2PHA A;  4BZ8 A;  4CQF A;  3THE A;  1ZZ0 A;  3GN0 A;  4IU5 A;  3E8Q A;  5CEV A;  3F0R A;  5EFJ D;  1WVA A;  3MMR A;  4Q3R C;  4QA4 A;  3NIP A;  1T4T A;  5DC5 A;  4Q3Q A;  1HQX A;  3F80 A;  1WVB A;  3SKK A;  2VQO A;  4IU1 A;  5DC6 A;  4QA6 A;  4QA7 A;  1D3V A;  4FCK A;  5G12 A;  2V5X A;  5D1C A;  4DZ4 A;  3ZNS A;  5BWZ A;  4BKX B;  5EF8 A;  1T67 A;  1T5G A;  4QA2 A;  5G3W A;  2CEV A;  1C3S A;  4MXR A;  4MYF A;  4GSZ A;  3Q9E A;  4HXQ A;  4Q3T A;  5D1B A;  2RLA A;  4RHL A;  4IE1 A;  4RHM A;  1P8N A;  4IU4 A;  4ZUO A;  1P8M A;  1WOH A;  4MYK A;  5RLA A;  4RN1 A;  3RQD A;  4Q3R A;  4QA3 A;  4GSV A;  5G0G A;  3MZ3 A;  3SFF A;  3MZ4 A;  1TBH A;  4ZUN A;  1P8R A;  1C3R A;  1WOG A;  5JI5 A;  4RN0 A;  3NIO A;  4G3H A;  5G0I A;  5THT A;  5THV A;  3LP7 A;  3SJT A;  2ZAV A;  4BZ7 A;  3MFW A;  1ZPE A;  3EZT A;  3MAX A;  3THH A;  1WOI A;  3THJ A;  4A69 A;  4BZ5 A;  5G1C A;  1GQ7 A;  4MYN A;  1ZZ1 A;  1T5F A;  5EEF A;  1HQF A;  1T69 A;  3SFH A;  1XFK A;  5IWG A;  4QA0 A;  4IU0 A;  4ZUR A;  3F07 A;  2V5W A;  3MEN A;  4LXZ A;  5FUE A;  5FCW A;  3E6K A;  5HJA A;  4Q3P A;  3LP4 A;  4IE2 A;  4Q40 A;  4Q41 A;  2EF5 A;  5A2S A;  4IE3 A;  5EFH A;  3E9B A;  4BZ6 A;  3MJL A;  1VKG A;  3C10 A;  4GWD A;  5HJ9 A;  3MZ7 A;  5EFG A;  5G1B A;  1HQH A;  4FCI A;  4RHJ A;  1GQ6 A;  4HZE A;  4RLA A;  4ZUP A;  5ICN B;  2AEB A;  1HQG A;  4IXU A;  5EEI A;  5G10 A;  1HQ5 A;  4QA5 A;  5G13 A;  3LHL A;  4CEV A;  3TH7 A;  1T64 A;  1CEV A;  1T4S A;  3MZ6 A;  3TF3 A;  1W22 A;  3SL0 A;  5THU A;  1T4P A;  2GH6 A;  3CEV A;  3E6V A;  5EFB D;  2A0M A; 
#chains in the Genus database with same CATH homology
 3DJ8 A;  4IXV A;  4RHI A;  1PQ3 A;  1P8O A;  4RHQ A;  1TBL A;  3PZL A;  1ZPG A;  4RHK A;  1TA1 A;  4HWW A;  4Q3U A;  1P8Q A;  4GWC A;  1P8S A;  1T4R A;  3RLA A;  4Q3V A;  1RLA A;  3NIQ A;  4Q3S A;  3M1R A;  1P8P A;  2EF4 A;  4Q42 A;  2EIV A;  4GSM A;  3E8Z A;  1R1O A;  2PHO A;  4MYL A;  3SL1 A;  3KV2 A;  4I06 A;  2PLL A;  1TBJ A;  4ITY A;  3GMZ A;  3MFV A;  2PHA A;  3THE A;  3GN0 A;  4IU5 A;  3E8Q A;  5CEV A;  1WVA A;  3MMR A;  4Q3R C;  3NIP A;  1T4T A;  4Q3Q A;  1HQX A;  3F80 A;  1WVB A;  3SKK A;  4IU1 A;  1D3V A;  4FCK A;  4DZ4 A;  1T5G A;  2CEV A;  4MXR A;  4MYF A;  4GSZ A;  4HXQ A;  4Q3T A;  2RLA A;  4RHL A;  4IE1 A;  4RHM A;  1P8N A;  4IU4 A;  1P8M A;  1WOH A;  4MYK A;  5RLA A;  4GSV A;  1TBH A;  1P8R A;  1WOG A;  3NIO A;  4G3H A;  3LP7 A;  3SJT A;  2ZAV A;  3MFW A;  1ZPE A;  3THJ A;  3THH A;  1WOI A;  1GQ7 A;  4MYN A;  1T5F A;  1HQF A;  1XFK A;  4IU0 A;  5HJA A;  3E6K A;  4Q3P A;  3LP4 A;  4IE2 A;  4Q40 A;  4Q41 A;  2EF5 A;  4IE3 A;  3E9B A;  3MJL A;  4GWD A;  5HJ9 A;  1HQH A;  4FCI A;  4RHJ A;  1GQ6 A;  4HZE A;  4RLA A;  2AEB A;  1HQG A;  4IXU A;  1HQ5 A;  3LHL A;  4CEV A;  3TH7 A;  1CEV A;  1T4S A;  3TF3 A;  3SL0 A;  1T4P A;  3CEV A;  3E6V A;  4Q3R A;  2A0M A; 
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similar chains in the Genus database (?% sequence similarity)
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