1WOIA

Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
Total Genus 114
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
Knots found
sequence length
303
structure length
303
Chain Sequence
GPAHLPYGGIPTFARAPLVQPDGDWQADVAALGVPFDIALGFRPGARFAPRALREASLRSVPPFTGLDGKTRLQGVTFADAGDVILPSLEPQLAHDRITEAARQVRGRCRVPVFLGGDHSVSYPLLRAFADVPDLHVVQLDAHLDFTDTRNDTKWSNSSPFRRACEALPNLVHITTVGLRGLRFDPEAVAAARARGHTIIPMDDVTADLAGVLAQLPRGQNVYFSVDVDGFDPAVIPGTSSPEPDGLTYAQGMKILAAAAANNTVVGLDLVELAPNLDPTGRSELLMARLVMETLCEVFDHVL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
pubmed doi rcsb
molecule tags Hydrolase
source organism Deinococcus radiodurans
molecule keywords agmatinase
total genus 114
structure length 303
sequence length 303
chains with identical sequence B, C, D, E, F
other databases KnotProt 2.0: S +31 +31 +31
ec nomenclature ec 3.5.3.11: Agmatinase.
pdb deposition date 2004-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 1woiA00
2PHAA 3MFWA 1ZPEA 5HJ9A 1CEVA 1PQ3A 4RHJA 1HQHA 2PLLA 1P8SA 3TF3A 4ITYA 1T4SA 1T4RA 4IXUA 4RLAA 4Q3UA 4RHKA 2RLAA 4Q40A 4IE1A 1T5GA 3GN0A 4FCKA 3MMRA 4Q42A 3THJA 1GQ7A 1P8RA 4Q3QA 3TH7A 3NIQA 3NIOA 3GMZA 4Q3VA 1HQFA 1P8NA 1R1OA 4Q3TA 3F80A 4Q3SA 3LHLA 3RLAA 4RHIA 3LP4A 2AEBA 1T5FA 4GWDA 4RHLA 1WVAA 1ZPGA 3SL0A 3E6VA 4IE2A 4IXVA 4Q41A 1TBJA 3MFVA 3THHA 4MXRA 4GSMA 1P8MA 2A0MA 3KV2A 4MYNA 4IU5A 4G3HA 3NIPA 2ZAVA 2EIVA 3MJLA 1GQ6A 1TA1A 4MYLA 2EF5A 1TBHA 1T4PA 3SKKA 1RLAA 4GSZA 3PZLA 4Q3PA 3DJ8A 1P8OA 1HQ5A 4HZEA 5RLAA 3SL1A 4MYFA 4I06A 3SJTA 4MYKA 1TBLA 4GSVA 4DZ4A 2EF4A 4FCIA 1P8QA 4IU1A 3THEA 2PHOA 4RHMA 4IU4A 3E6KA 4HXQA 2CEVA 1WVBA 1D3VA 3LP7A 4RHQA 4HWWA 5HJAA 4Q3RC 3CEVA 1WOGA 4Q3RA 1XFKA 1T4TA 4IE3A 5CEVA 4GWCA 1WOIA 4IU0A 3E8QA 3M1RA 1HQXA 1P8PA 3E9BA 1HQGA 4CEVA 3E8ZA 1WOHA
chains in the Genus database with same CATH superfamily
4ZUOA 2PHAA 5JI5A 3MENA 3MFWA 4QA4A 1ZPEA 4QA2A 3C10A 3MZ6A 5HJ9A 3SFHA 1CEVA 1PQ3A 4RHJA 4QA5A 4BZ6A 1HQHA 5D1BA 5EFGA 2PLLA 5G0YA 1P8SA 5G12A 3MZ3A 3TF3A 4LY1A 1W22A 4ITYA 4CQFA 1T4SA 1T4RA 4QA1A 4IXUA 5G17A 4QA3A 4RLAA 4Q3UA 4ZUNA 4RHKA 2RLAA 4Q40A 5THTA 4IE1A 1C3PA 1T5GA 3GN0A 4FCKA 3MMRA 5EFHA 5IX0A 4QA7A 4Q42A 3THJA 3F0RA 1GQ7A 1P8RA 4Q3QA 5EEMA 3MZ4A 2VQMA 3TH7A 5THVA 3NIQA 5ICNB 4ZUPA 3NIOA 3GMZA 4Q3VA 5EENA 4RN1A 4BKXB 1HQFA 1P8NA 1R1OA 4Q3TA 5DC5A 3F80A 5D1DA 4Q3SA 3LHLA 3EZTA 3RLAA 4RHIA 3LP4A 4QA6A 2AEBA 3Q9FA 4A69A 1T5FA 4GWDA 4BZ5A 4RHLA 4BZ9A 1WVAA 1WOHA 1ZPGA 3SL0A 3E6VA 5THUA 4IE2A 4IXVA 3ZNRA 1C3RA 4Q41A 1TBJA 5G13A 3MFVA 3THHA 5FCWA 3F07A 4GSMA 4MXRA 3Q9BA 4RN0A 5DC7A 1P8MA 4ZURA 3EZPA 3C0ZA 5G0HA 2A0MA 3KV2A 4LXZA 4MYNA 2VQJA 3EWFA 4IU5A 5G0JA 4G3HA 5G0GA 2VQQA 3NIPA 2ZAVA 2EIVA 5EFJD 3MJLA 5EEIA 1GQ6A 5EEFA 4ZUQA 1TA1A 3Q9CA 4RN2A 5EEKA 4MYLA 5G1CA 5DC6A 2VQOA 1T64A 5G0IA 2EF5A 1TBHA 1T4PA 3SKKA 1RLAA 4GSZA 3PZLA 5G1AA 4Q3PA 3C0YA 1P8OA 1HQ5A 3DJ8A 4HZEA 5RLAA 3F06A 2V5XA 3SL1A 4MYFA 4I06A 3EW8A 2VCGA 3ZNSA 5DC8A 3MAXA 3SJTA 1T67A 2VQWG 4ZUMA 4MYKA 5EF8A 1TBLA 4GSVA 4DZ4A 1ZZ3A 2V5WA 1VKGA 2EF4A 4FCIA 1P8QA 3RQDA 4BZ7A 5G10A 4IU1A 5IWGA 5G11A 3THEA 2PHOA 2VQVA 1C3SA 5BWZA 4RHMA 4IU4A 5EF7A 5THSA 3E6KA 4HXQA 2CEVA 1WVBA 2GH6A 4CBTA 1D3VA 3LP7A 4BZ8A 4RHQA 5EFBD 5EFKB 5G3WA 4HWWA 5HJAA 3Q9EA 3MZ7A 4Q3RC 3CEVA 5G0XA 5D1CA 5G1BA 3SFFA 1WOGA 4Q3RA 1T69A 1XFKA 1T4TA 4IE3A 4QA0A 5EFNA 5A2SA 5CEVA 4CBYA 4GWCA 1WOIA 5FUEA 4IU0A 3E8QA 3M1RA 1HQXA 1P8PA 1ZZ1A 3E9BA 1HQGA 4CEVA 3E8ZA 1ZZ0A 5LI3A
chains in the Genus database with same CATH topology
2PHAA 3MFWA 1ZPEA 5HJ9A 1CEVA 1PQ3A 4RHJA 1HQHA 2PLLA 1P8SA 3TF3A 4ITYA 1T4SA 1T4RA 4IXUA 4RLAA 4Q3UA 4RHKA 2RLAA 4Q40A 4IE1A 1T5GA 3GN0A 4FCKA 3MMRA 4Q42A 3THJA 1GQ7A 1P8RA 4Q3QA 3TH7A 3NIQA 3NIOA 3GMZA 4Q3VA 1HQFA 1P8NA 1R1OA 4Q3TA 3F80A 4Q3SA 3LHLA 3RLAA 4RHIA 3LP4A 2AEBA 1T5FA 4GWDA 4RHLA 1WVAA 1ZPGA 3SL0A 3E6VA 4IE2A 4IXVA 4Q41A 1TBJA 3MFVA 3THHA 4MXRA 4GSMA 1P8MA 2A0MA 3KV2A 4MYNA 4IU5A 4G3HA 3NIPA 2ZAVA 2EIVA 3MJLA 1GQ6A 1TA1A 4MYLA 2EF5A 1TBHA 1T4PA 3SKKA 1RLAA 4GSZA 3PZLA 4Q3PA 3DJ8A 1P8OA 1HQ5A 4HZEA 5RLAA 3SL1A 4MYFA 4I06A 3SJTA 4MYKA 1TBLA 4GSVA 4DZ4A 2EF4A 4FCIA 1P8QA 4IU1A 3THEA 2PHOA 4RHMA 4IU4A 3E6KA 4HXQA 2CEVA 1WVBA 1D3VA 3LP7A 4RHQA 4HWWA 5HJAA 4Q3RC 3CEVA 1WOGA 4Q3RA 1XFKA 1T4TA 4IE3A 5CEVA 4GWCA 1WOIA 4IU0A 3E8QA 3M1RA 1HQXA 1P8PA 3E9BA 1HQGA 4CEVA 3E8ZA 1WOHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PHA A;  3MFW A;  1ZPE A;  5HJ9 A;  1CEV A;  1PQ3 A;  4RHJ A;  1HQH A;  2PLL A;  1P8S A;  3TF3 A;  4ITY A;  1T4S A;  1T4R A;  4IXU A;  4RLA A;  4Q3U A;  4RHK A;  2RLA A;  4Q40 A;  4IE1 A;  1T5G A;  3GN0 A;  4FCK A;  3MMR A;  4Q42 A;  3THJ A;  1GQ7 A;  1P8R A;  4Q3Q A;  3TH7 A;  3NIQ A;  3NIO A;  3GMZ A;  4Q3V A;  1HQF A;  1P8N A;  1R1O A;  4Q3T A;  3F80 A;  4Q3S A;  3LHL A;  3RLA A;  4RHI A;  3LP4 A;  2AEB A;  1T5F A;  4GWD A;  4RHL A;  1WVA A;  1ZPG A;  3SL0 A;  3E6V A;  4IE2 A;  4IXV A;  4Q41 A;  1TBJ A;  3MFV A;  3THH A;  4MXR A;  4GSM A;  1P8M A;  2A0M A;  3KV2 A;  4MYN A;  4IU5 A;  4G3H A;  3NIP A;  2ZAV A;  2EIV A;  3MJL A;  1GQ6 A;  1TA1 A;  4MYL A;  2EF5 A;  1TBH A;  1T4P A;  3SKK A;  1RLA A;  4GSZ A;  3PZL A;  4Q3P A;  3DJ8 A;  1P8O A;  1HQ5 A;  4HZE A;  5RLA A;  3SL1 A;  4MYF A;  4I06 A;  3SJT A;  4MYK A;  1TBL A;  4GSV A;  4DZ4 A;  2EF4 A;  4FCI A;  1P8Q A;  4IU1 A;  3THE A;  2PHO A;  4RHM A;  4IU4 A;  3E6K A;  4HXQ A;  2CEV A;  1WVB A;  1D3V A;  3LP7 A;  4RHQ A;  4HWW A;  5HJA A;  4Q3R C;  3CEV A;  1WOG A;  4Q3R A;  1XFK A;  1T4T A;  4IE3 A;  5CEV A;  4GWC A;  1WOI A;  4IU0 A;  3E8Q A;  3M1R A;  1HQX A;  1P8P A;  3E9B A;  1HQG A;  4CEV A;  3E8Z A;  1WOH A; 
#chains in the Genus database with same CATH topology
 4ZUO A;  2PHA A;  5JI5 A;  3MEN A;  3MFW A;  4QA4 A;  1ZPE A;  4QA2 A;  3C10 A;  3MZ6 A;  5HJ9 A;  3SFH A;  1CEV A;  1PQ3 A;  4RHJ A;  4QA5 A;  4BZ6 A;  1HQH A;  5D1B A;  5EFG A;  2PLL A;  5G0Y A;  1P8S A;  5G12 A;  3MZ3 A;  3TF3 A;  4LY1 A;  1W22 A;  4ITY A;  4CQF A;  1T4S A;  1T4R A;  4QA1 A;  4IXU A;  5G17 A;  4QA3 A;  4RLA A;  4Q3U A;  4ZUN A;  4RHK A;  2RLA A;  4Q40 A;  5THT A;  4IE1 A;  1C3P A;  1T5G A;  3GN0 A;  4FCK A;  3MMR A;  5EFH A;  5IX0 A;  4QA7 A;  4Q42 A;  3THJ A;  3F0R A;  1GQ7 A;  1P8R A;  4Q3Q A;  5EEM A;  3MZ4 A;  2VQM A;  3TH7 A;  5THV A;  3NIQ A;  5ICN B;  4ZUP A;  3NIO A;  3GMZ A;  4Q3V A;  5EEN A;  4RN1 A;  4BKX B;  1HQF A;  1P8N A;  1R1O A;  4Q3T A;  5DC5 A;  3F80 A;  5D1D A;  4Q3S A;  3LHL A;  3EZT A;  3RLA A;  4RHI A;  3LP4 A;  4QA6 A;  2AEB A;  3Q9F A;  4A69 A;  1T5F A;  4GWD A;  4BZ5 A;  4RHL A;  4BZ9 A;  1WVA A;  1WOH A;  1ZPG A;  3SL0 A;  3E6V A;  5THU A;  4IE2 A;  4IXV A;  3ZNR A;  1C3R A;  4Q41 A;  1TBJ A;  5G13 A;  3MFV A;  3THH A;  5FCW A;  3F07 A;  4GSM A;  4MXR A;  3Q9B A;  4RN0 A;  5DC7 A;  1P8M A;  4ZUR A;  3EZP A;  3C0Z A;  5G0H A;  2A0M A;  3KV2 A;  4LXZ A;  4MYN A;  2VQJ A;  3EWF A;  4IU5 A;  5G0J A;  4G3H A;  5G0G A;  2VQQ A;  3NIP A;  2ZAV A;  2EIV A;  5EFJ D;  3MJL A;  5EEI A;  1GQ6 A;  5EEF A;  4ZUQ A;  1TA1 A;  3Q9C A;  4RN2 A;  5EEK A;  4MYL A;  5G1C A;  5DC6 A;  2VQO A;  1T64 A;  5G0I A;  2EF5 A;  1TBH A;  1T4P A;  3SKK A;  1RLA A;  4GSZ A;  3PZL A;  5G1A A;  4Q3P A;  3C0Y A;  1P8O A;  1HQ5 A;  3DJ8 A;  4HZE A;  5RLA A;  3F06 A;  2V5X A;  3SL1 A;  4MYF A;  4I06 A;  3EW8 A;  2VCG A;  3ZNS A;  5DC8 A;  3MAX A;  3SJT A;  1T67 A;  2VQW G;  4ZUM A;  4MYK A;  5EF8 A;  1TBL A;  4GSV A;  4DZ4 A;  1ZZ3 A;  2V5W A;  1VKG A;  2EF4 A;  4FCI A;  1P8Q A;  3RQD A;  4BZ7 A;  5G10 A;  4IU1 A;  5IWG A;  5G11 A;  3THE A;  2PHO A;  2VQV A;  1C3S A;  5BWZ A;  4RHM A;  4IU4 A;  5EF7 A;  5THS A;  3E6K A;  4HXQ A;  2CEV A;  1WVB A;  2GH6 A;  4CBT A;  1D3V A;  3LP7 A;  4BZ8 A;  4RHQ A;  5EFB D;  5EFK B;  5G3W A;  4HWW A;  5HJA A;  3Q9E A;  3MZ7 A;  4Q3R C;  3CEV A;  5G0X A;  5D1C A;  5G1B A;  3SFF A;  1WOG A;  4Q3R A;  1T69 A;  1XFK A;  1T4T A;  4IE3 A;  4QA0 A;  5EFN A;  5A2S A;  5CEV A;  4CBY A;  4GWC A;  1WOI A;  5FUE A;  4IU0 A;  3E8Q A;  3M1R A;  1HQX A;  1P8P A;  1ZZ1 A;  3E9B A;  1HQG A;  4CEV A;  3E8Z A;  1ZZ0 A;  5LI3 A; 
#chains in the Genus database with same CATH homology
 2PHA A;  3MFW A;  1ZPE A;  5HJ9 A;  1CEV A;  1PQ3 A;  4RHJ A;  1HQH A;  2PLL A;  1P8S A;  3TF3 A;  4ITY A;  1T4S A;  1T4R A;  4IXU A;  4RLA A;  4Q3U A;  4RHK A;  2RLA A;  4Q40 A;  4IE1 A;  1T5G A;  3GN0 A;  4FCK A;  3MMR A;  4Q42 A;  3THJ A;  1GQ7 A;  1P8R A;  4Q3Q A;  3TH7 A;  3NIQ A;  3NIO A;  3GMZ A;  4Q3V A;  1HQF A;  1P8N A;  1R1O A;  4Q3T A;  3F80 A;  4Q3S A;  3LHL A;  3RLA A;  4RHI A;  3LP4 A;  2AEB A;  1T5F A;  4GWD A;  4RHL A;  1WVA A;  1ZPG A;  3SL0 A;  3E6V A;  4IE2 A;  4IXV A;  4Q41 A;  1TBJ A;  3MFV A;  3THH A;  4MXR A;  4GSM A;  1P8M A;  2A0M A;  3KV2 A;  4MYN A;  4IU5 A;  4G3H A;  3NIP A;  2ZAV A;  2EIV A;  3MJL A;  1GQ6 A;  1TA1 A;  4MYL A;  2EF5 A;  1TBH A;  1T4P A;  3SKK A;  1RLA A;  4GSZ A;  3PZL A;  4Q3P A;  3DJ8 A;  1P8O A;  1HQ5 A;  4HZE A;  5RLA A;  3SL1 A;  4MYF A;  4I06 A;  3SJT A;  4MYK A;  1TBL A;  4GSV A;  4DZ4 A;  2EF4 A;  4FCI A;  1P8Q A;  4IU1 A;  3THE A;  2PHO A;  4RHM A;  4IU4 A;  3E6K A;  4HXQ A;  2CEV A;  1WVB A;  1D3V A;  3LP7 A;  4RHQ A;  4HWW A;  5HJA A;  4Q3R C;  3CEV A;  1WOG A;  4Q3R A;  1XFK A;  1T4T A;  4IE3 A;  5CEV A;  4GWC A;  1WOI A;  4IU0 A;  3E8Q A;  3M1R A;  1HQX A;  1P8P A;  3E9B A;  1HQG A;  4CEV A;  3E8Z A;  1WOH A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...