1MQ0 | Genus

Total Genus 31

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	31
sequence length	130
structure length	130
Chain Sequence	ECVQQLLVCSQEAKQSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKPDGTYIVMTVQELLPSSFGPEDL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Homo sapiens
publication title	Structure of human cytidine deaminase bound to a potent inhibitor pubmed doi rcsb
molecule keywords	Cytidine Deaminase
total genus	31
structure length	130
sequence length	130
chains with identical sequence	B
ec nomenclature	ec 3.5.4.5: Cytidine deaminase.
pdb deposition date	2002-09-13

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00383	dCMP_cyt_deam_1	Cytidine and deoxycytidylate deaminase zinc-binding region

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.140.10	Alpha Beta	3-Layer(aba) Sandwich	Cytidine Deaminase; domain 2	Cytidine Deaminase, domain 2	1mq0A00

5M59B 4MSDA 2O95A 2QLCA 1CTUA 1UWZA 1JTKA 4JXEA 3OCQA 1YSDA 2OG4A 2KKSA 4O8YA 2PW9A 2KCQA 1R5TA 3DMOA 1ALNA 4QFTA 2OBCA 4LCPA 2G84A 4LCOA 4LC5A 2FR5A 4ZFTA 2NYTA 2O7PA 3OJ6A 4OCLA 4D10F 1YSBA 2HVWA 2O96A 2HXVA 2RPZA 1WKQA 4O8XA 1AF2A 5DCAJ 1WWRA 1ZABA 4OCNA 2D5NA 4ILGC 4O8YB 1MQ0A 1UX1A 4P9CA 1OX7A 4F7OA 5M52C 4OWPA 1OI0A 3G8QA 4P9DA 4K1RA 4E0QA 3RZUA 2HVVA 2ZNVA 4MSJA 3RZVA 4OCMA 2W4LA 4G3MA 3MPZA 4I43B 4OCNB 1WN6A 3ZPGA 3ZEFB 4LCNA 1Z3AA 2FR6A 4OWPB 2O3KA 1RB7A 1VQ2A 4MSMA 1P6OA 2D30A 1WN5A 2P8RA 5CW6A 4OCLB 4KITC 4ZFRA 4OCMB 1R5XA 1UX0A 2Z3GA 1TIYA 3R2NA 4LD2A 4WIFA 4PQTA 4HRQA 4F3WA 4O8XB 5GAOA 4MSQA 3E1UA 4ZD5A 2Z3HA 4EG2A 3ZPCA 2Z3JA 2NX8A 4NQLA 2ZNRA 3DH1A 4MS7A 4HRWA 2A8NA 4P9EA 2B3JA 1UAQA 2P87A 3B8FA 3IJFX 3EX8A 4WIGA 3SBGA 1CTTA 2B3ZA 5C2OA 4ZD4A 4BGDC 2Z3IA 2G6VA 4LD4A
chains in the Genus database with same CATH superfamily

5M59B 4MSDA 2O95A 2QLCA 1CTUA 1UWZA 1JTKA 4JXEA 3OCQA 1YSDA 2OG4A 2KKSA 2IU3A 4O8YA 2PW9A 2KCQA 1R5TA 3DMOA 1ALNA 4QFTA 4EHIA 2OBCA 4LCPA 2G84A 4LCOA 4LC5A 2FR5A 4ZFTA 2NYTA 2O7PA 1THZA 3OJ6A 4OCLA 4D10F 1YSBA 2HVWA 2O96A 2HXVA 2RPZA 1M9NA 1WKQA 4O8XA 1AF2A 5DCAJ 1PKXA 1WWRA 1ZABA 4OCNA 4GGMX 2D5NA 4ILGC 4O8YB 1MQ0A 1UX1A 4P9CA 1OX7A 1VK9A 4F7OA 5M52C 4A1OA 4OWPA 1OI0A 3G8QA 4J6EA 4P9DA 4K1RA 4E0QA 3RZUA 1G8MA 2HVVA 2ZNVA 4MSJA 2B1GA 4OCMA 3RZVA 2W4LA 4G3MA 1ZCZA 3MPZA 4I43B 4OCNB 1WN6A 1OZ0A 3ZPGA 3ZEFB 4LCNA 1Z3AA 2FR6A 4OWPB 2O3KA 1RB7A 1VQ2A 4MSMA 1P6OA 2D30A 1WN5A 2P8RA 5CW6A 4OCLB 4KITC 4ZFRA 4OCMB 1R5XA 1UX0A 2Z3GA 1TIYA 3R2NA 4LD2A 4WIFA 4PQTA 4HRQA 4F3WA 4O8XB 1P4RA 5GAOA 4MSQA 3E1UA 4ZD5A 2Z3HA 4EG2A 3ZPCA 1PL0A 2NX8A 2Z3JA 2ZNRA 4NQLA 3DH1A 4MS7A 4HRWA 2B1IA 2A8NA 4P9EA 2B3JA 1UAQA 2P87A 3B8FA 2IU0A 3IJFX 3EX8A 4WIGA 3BH1A 3SBGA 1CTTA 2B3ZA 3ZZMA 5C2OA 4ZD4A 3VX8A 4BGDC 2Z3IA 2G6VA 4LD4A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 5M59 B;  4MSD A;  2O95 A;  2QLC A;  1CTU A;  1UWZ A;  1JTK A;  4JXE A;  3OCQ A;  1YSD A;  2OG4 A;  2KKS A;  4O8Y A;  2PW9 A;  2KCQ A;  1R5T A;  3DMO A;  1ALN A;  4QFT A;  2OBC A;  4LCP A;  2G84 A;  4LCO A;  4LC5 A;  2FR5 A;  4ZFT A;  2NYT A;  2O7P A;  3OJ6 A;  4OCL A;  4D10 F;  1YSB A;  2HVW A;  2O96 A;  2HXV A;  2RPZ A;  1WKQ A;  4O8X A;  1AF2 A;  5DCA J;  1WWR A;  1ZAB A;  4OCN A;  2D5N A;  4ILG C;  4O8Y B;  1MQ0 A;  1UX1 A;  4P9C A;  1OX7 A;  4F7O A;  5M52 C;  4OWP A;  1OI0 A;  3G8Q A;  4P9D A;  4K1R A;  4E0Q A;  3RZU A;  2HVV A;  2ZNV A;  4MSJ A;  3RZV A;  4OCM A;  2W4L A;  4G3M A;  3MPZ A;  4I43 B;  4OCN B;  1WN6 A;  3ZPG A;  3ZEF B;  4LCN A;  1Z3A A;  2FR6 A;  4OWP B;  2O3K A;  1RB7 A;  1VQ2 A;  4MSM A;  1P6O A;  2D30 A;  1WN5 A;  2P8R A;  5CW6 A;  4OCL B;  4KIT C;  4ZFR A;  4OCM B;  1R5X A;  1UX0 A;  2Z3G A;  1TIY A;  3R2N A;  4LD2 A;  4WIF A;  4PQT A;  4HRQ A;  4F3W A;  4O8X B;  5GAO A;  4MSQ A;  3E1U A;  4ZD5 A;  2Z3H A;  4EG2 A;  3ZPC A;  2Z3J A;  2NX8 A;  4NQL A;  2ZNR A;  3DH1 A;  4MS7 A;  4HRW A;  2A8N A;  4P9E A;  2B3J A;  1UAQ A;  2P87 A;  3B8F A;  3IJF X;  3EX8 A;  4WIG A;  3SBG A;  1CTT A;  2B3Z A;  5C2O A;  4ZD4 A;  4BGD C;  2Z3I A;  2G6V A;  4LD4 A; 
#chains in the Genus database with same CATH topology
 5M59 B;  4MSD A;  2O95 A;  2QLC A;  1CTU A;  1UWZ A;  1JTK A;  4JXE A;  3OCQ A;  1YSD A;  2OG4 A;  2KKS A;  2IU3 A;  4O8Y A;  2PW9 A;  2KCQ A;  1R5T A;  3DMO A;  1ALN A;  4QFT A;  4EHI A;  2OBC A;  4LCP A;  2G84 A;  4LCO A;  4LC5 A;  2FR5 A;  4ZFT A;  2NYT A;  2O7P A;  1THZ A;  3OJ6 A;  4OCL A;  4D10 F;  1YSB A;  2HVW A;  2O96 A;  2HXV A;  2RPZ A;  1M9N A;  1WKQ A;  4O8X A;  1AF2 A;  5DCA J;  1PKX A;  1WWR A;  1ZAB A;  4OCN A;  4GGM X;  2D5N A;  4ILG C;  4O8Y B;  1MQ0 A;  1UX1 A;  4P9C A;  1OX7 A;  1VK9 A;  4F7O A;  5M52 C;  4A1O A;  4OWP A;  1OI0 A;  3G8Q A;  4J6E A;  4P9D A;  4K1R A;  4E0Q A;  3RZU A;  1G8M A;  2HVV A;  2ZNV A;  4MSJ A;  2B1G A;  4OCM A;  3RZV A;  2W4L A;  4G3M A;  1ZCZ A;  3MPZ A;  4I43 B;  4OCN B;  1WN6 A;  1OZ0 A;  3ZPG A;  3ZEF B;  4LCN A;  1Z3A A;  2FR6 A;  4OWP B;  2O3K A;  1RB7 A;  1VQ2 A;  4MSM A;  1P6O A;  2D30 A;  1WN5 A;  2P8R A;  5CW6 A;  4OCL B;  4KIT C;  4ZFR A;  4OCM B;  1R5X A;  1UX0 A;  2Z3G A;  1TIY A;  3R2N A;  4LD2 A;  4WIF A;  4PQT A;  4HRQ A;  4F3W A;  4O8X B;  1P4R A;  5GAO A;  4MSQ A;  3E1U A;  4ZD5 A;  2Z3H A;  4EG2 A;  3ZPC A;  1PL0 A;  2NX8 A;  2Z3J A;  2ZNR A;  4NQL A;  3DH1 A;  4MS7 A;  4HRW A;  2B1I A;  2A8N A;  4P9E A;  2B3J A;  1UAQ A;  2P87 A;  3B8F A;  2IU0 A;  3IJF X;  3EX8 A;  4WIG A;  3BH1 A;  3SBG A;  1CTT A;  2B3Z A;  3ZZM A;  5C2O A;  4ZD4 A;  3VX8 A;  4BGD C;  2Z3I A;  2G6V A;  4LD4 A; 
#chains in the Genus database with same CATH homology
 5M59 B;  4MSD A;  2O95 A;  2QLC A;  1CTU A;  1UWZ A;  1JTK A;  4JXE A;  3OCQ A;  1YSD A;  2OG4 A;  2KKS A;  4O8Y A;  2PW9 A;  2KCQ A;  1R5T A;  3DMO A;  1ALN A;  4QFT A;  2OBC A;  4LCP A;  2G84 A;  4LCO A;  4LC5 A;  2FR5 A;  4ZFT A;  2NYT A;  2O7P A;  3OJ6 A;  4OCL A;  4D10 F;  1YSB A;  2HVW A;  2O96 A;  2HXV A;  2RPZ A;  1WKQ A;  4O8X A;  1AF2 A;  5DCA J;  1WWR A;  1ZAB A;  4OCN A;  2D5N A;  4ILG C;  4O8Y B;  1MQ0 A;  1UX1 A;  4P9C A;  1OX7 A;  4F7O A;  5M52 C;  4OWP A;  1OI0 A;  3G8Q A;  4P9D A;  4K1R A;  4E0Q A;  3RZU A;  2HVV A;  2ZNV A;  4MSJ A;  3RZV A;  4OCM A;  2W4L A;  4G3M A;  3MPZ A;  4I43 B;  4OCN B;  1WN6 A;  3ZPG A;  3ZEF B;  4LCN A;  1Z3A A;  2FR6 A;  4OWP B;  2O3K A;  1RB7 A;  1VQ2 A;  4MSM A;  1P6O A;  2D30 A;  1WN5 A;  2P8R A;  5CW6 A;  4OCL B;  4KIT C;  4ZFR A;  4OCM B;  1R5X A;  1UX0 A;  2Z3G A;  1TIY A;  3R2N A;  4LD2 A;  4WIF A;  4PQT A;  4HRQ A;  4F3W A;  4O8X B;  5GAO A;  4MSQ A;  3E1U A;  4ZD5 A;  2Z3H A;  4EG2 A;  3ZPC A;  2Z3J A;  2NX8 A;  4NQL A;  2ZNR A;  3DH1 A;  4MS7 A;  4HRW A;  2A8N A;  4P9E A;  2B3J A;  1UAQ A;  2P87 A;  3B8F A;  3IJF X;  3EX8 A;  4WIG A;  3SBG A;  1CTT A;  2B3Z A;  5C2O A;  4ZD4 A;  4BGD C;  2Z3I A;  2G6V A;  4LD4 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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1MQ0A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations