1MQ0A

Crystal structure of human cytidine deaminase
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
130
structure length
130
Chain Sequence
ECVQQLLVCSQEAKQSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKPDGTYIVMTVQELLPSSFGPEDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human cytidine deaminase bound to a potent inhibitor
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cytidine Deaminase
total genus 31
structure length 130
sequence length 130
chains with identical sequence B
ec nomenclature ec 3.5.4.5: Cytidine deaminase.
pdb deposition date 2002-09-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00383 dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc-binding region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.140.10 Alpha Beta 3-Layer(aba) Sandwich Cytidine Deaminase; domain 2 Cytidine Deaminase, domain 2 1mq0A00
2PW9A 4MS7A 4NQLA 2B3ZA 2Z3JA 4P9EA 4BGDC 1R5TA 1WKQA 4I43B 4F3WA 1R5XA 4O8YA 3OJ6A 1AF2A 2KCQA 4F7OA 2A8NA 4OWPB 3RZVA 4KITC 4O8YB 4LCOA 4K1RA 2OG4A 5GAOA 1MQ0A 3EX8A 2P8RA 2D5NA 4PQTA 4MSDA 2HVWA 3ZPGA 2RPZA 4LCNA 3ZEFB 1WN5A 4LD4A 4D10F 2ZNVA 3R2NA 2Z3IA 3OCQA 4MSMA 4LC5A 4MSJA 3ZPCA 2ZNRA 5DCAJ 1CTUA 3DMOA 1RB7A 1UX1A 3DH1A 3E1UA 4QFTA 2O7PA 2O95A 4MSQA 2OBCA 2QLCA 2P87A 4ZFRA 2D30A 4P9CA 5CW6A 1OI0A 2HXVA 2Z3GA 2NX8A 4WIFA 2B3JA 4LD2A 2FR5A 2G6VA 5M52C 3RZUA 1UX0A 1WWRA 4HRWA 1YSBA 4OCLA 2Z3HA 4WIGA 3SBGA 4OCLB 4ZD5A 2NYTA 1ZABA 4ZD4A 2G84A 1ALNA 4O8XA 1YSDA 4OCMA 1Z3AA 1TIYA 1WN6A 1UAQA 4JXEA 4HRQA 2FR6A 4EG2A 5C2OA 4G3MA 3B8FA 2O96A 4OWPA 4OCNA 1OX7A 2HVVA 1VQ2A 1P6OA 4LCPA 3IJFX 4E0QA 4OCNB 1UWZA 1JTKA 2KKSA 3MPZA 5M59B 2O3KA 4P9DA 2W4LA 3G8QA 4ILGC 4O8XB 4OCMB 1CTTA 4ZFTA
chains in the Genus database with same CATH superfamily
2PW9A 4MS7A 4NQLA 4A1OA 1PL0A 2B3ZA 2Z3JA 4P9EA 4BGDC 1R5TA 1WKQA 4I43B 4F3WA 1R5XA 4O8YA 3OJ6A 1AF2A 2KCQA 1M9NA 4F7OA 2A8NA 4OWPB 3RZVA 4KITC 4O8YB 4LCOA 4K1RA 2OG4A 5GAOA 1MQ0A 3EX8A 2P8RA 2D5NA 4PQTA 4MSDA 2HVWA 3ZPGA 2RPZA 4LCNA 3ZEFB 2B1IA 1WN5A 4LD4A 4D10F 2ZNVA 3R2NA 2Z3IA 3OCQA 4MSMA 4LC5A 2B1GA 4MSJA 3ZPCA 2ZNRA 5DCAJ 1CTUA 3DMOA 1RB7A 1UX1A 3DH1A 3E1UA 4QFTA 2O7PA 2O95A 4MSQA 2OBCA 2QLCA 2P87A 1P4RA 4ZFRA 3BH1A 2D30A 4P9CA 5CW6A 1OI0A 2HXVA 2Z3GA 2NX8A 1PKXA 4WIFA 2B3JA 4LD2A 3VX8A 2FR5A 2G6VA 5M52C 3ZZMA 3RZUA 1UX0A 1WWRA 4HRWA 1YSBA 4OCLA 2Z3HA 4WIGA 3SBGA 4OCLB 1G8MA 4ZD5A 2NYTA 1ZABA 4ZD4A 2G84A 1ALNA 4O8XA 1YSDA 4OCMA 1Z3AA 4J6EA 1TIYA 1WN6A 1UAQA 4JXEA 4HRQA 4EHIA 2FR6A 1ZCZA 4EG2A 5C2OA 4G3MA 3B8FA 2O96A 4OWPA 2IU0A 4OCNA 1OX7A 2HVVA 1VQ2A 1P6OA 4LCPA 1OZ0A 3IJFX 4E0QA 4OCNB 1JTKA 1UWZA 2KKSA 2IU3A 3MPZA 5M59B 1VK9A 2O3KA 4P9DA 2W4LA 3G8QA 4ILGC 4O8XB 4OCMB 1THZA 1CTTA 4ZFTA 4GGMX
chains in the Genus database with same CATH topology
2PW9A 4MS7A 4NQLA 2B3ZA 2Z3JA 4P9EA 4BGDC 1R5TA 1WKQA 4I43B 4F3WA 1R5XA 4O8YA 3OJ6A 1AF2A 2KCQA 4F7OA 2A8NA 4OWPB 3RZVA 4KITC 4O8YB 4LCOA 4K1RA 2OG4A 5GAOA 1MQ0A 3EX8A 2P8RA 2D5NA 4PQTA 4MSDA 2HVWA 3ZPGA 2RPZA 4LCNA 3ZEFB 1WN5A 4LD4A 4D10F 2ZNVA 3R2NA 2Z3IA 3OCQA 4MSMA 4LC5A 4MSJA 3ZPCA 2ZNRA 5DCAJ 1CTUA 3DMOA 1RB7A 1UX1A 3DH1A 3E1UA 4QFTA 2O7PA 2O95A 4MSQA 2OBCA 2QLCA 2P87A 4ZFRA 2D30A 4P9CA 5CW6A 1OI0A 2HXVA 2Z3GA 2NX8A 4WIFA 2B3JA 4LD2A 2FR5A 2G6VA 5M52C 3RZUA 1UX0A 1WWRA 4HRWA 1YSBA 4OCLA 2Z3HA 4WIGA 3SBGA 4OCLB 4ZD5A 2NYTA 1ZABA 4ZD4A 2G84A 1ALNA 4O8XA 1YSDA 4OCMA 1Z3AA 1TIYA 1WN6A 1UAQA 4JXEA 4HRQA 2FR6A 4EG2A 5C2OA 4G3MA 3B8FA 2O96A 4OWPA 4OCNA 1OX7A 2HVVA 1VQ2A 1P6OA 4LCPA 3IJFX 4E0QA 4OCNB 1UWZA 1JTKA 2KKSA 3MPZA 5M59B 2O3KA 4P9DA 2W4LA 3G8QA 4ILGC 4O8XB 4OCMB 1CTTA 4ZFTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PW9 A;  4MS7 A;  4NQL A;  2B3Z A;  2Z3J A;  4P9E A;  4BGD C;  1R5T A;  1WKQ A;  4I43 B;  4F3W A;  1R5X A;  4O8Y A;  3OJ6 A;  1AF2 A;  2KCQ A;  4F7O A;  2A8N A;  4OWP B;  3RZV A;  4KIT C;  4O8Y B;  4LCO A;  4K1R A;  2OG4 A;  5GAO A;  1MQ0 A;  3EX8 A;  2P8R A;  2D5N A;  4PQT A;  4MSD A;  2HVW A;  3ZPG A;  2RPZ A;  4LCN A;  3ZEF B;  1WN5 A;  4LD4 A;  4D10 F;  2ZNV A;  3R2N A;  2Z3I A;  3OCQ A;  4MSM A;  4LC5 A;  4MSJ A;  3ZPC A;  2ZNR A;  5DCA J;  1CTU A;  3DMO A;  1RB7 A;  1UX1 A;  3DH1 A;  3E1U A;  4QFT A;  2O7P A;  2O95 A;  4MSQ A;  2OBC A;  2QLC A;  2P87 A;  4ZFR A;  2D30 A;  4P9C A;  5CW6 A;  1OI0 A;  2HXV A;  2Z3G A;  2NX8 A;  4WIF A;  2B3J A;  4LD2 A;  2FR5 A;  2G6V A;  5M52 C;  3RZU A;  1UX0 A;  1WWR A;  4HRW A;  1YSB A;  4OCL A;  2Z3H A;  4WIG A;  3SBG A;  4OCL B;  4ZD5 A;  2NYT A;  1ZAB A;  4ZD4 A;  2G84 A;  1ALN A;  4O8X A;  1YSD A;  4OCM A;  1Z3A A;  1TIY A;  1WN6 A;  1UAQ A;  4JXE A;  4HRQ A;  2FR6 A;  4EG2 A;  5C2O A;  4G3M A;  3B8F A;  2O96 A;  4OWP A;  4OCN A;  1OX7 A;  2HVV A;  1VQ2 A;  1P6O A;  4LCP A;  3IJF X;  4E0Q A;  4OCN B;  1UWZ A;  1JTK A;  2KKS A;  3MPZ A;  5M59 B;  2O3K A;  4P9D A;  2W4L A;  3G8Q A;  4ILG C;  4O8X B;  4OCM B;  1CTT A;  4ZFT A; 
#chains in the Genus database with same CATH topology
 2PW9 A;  4MS7 A;  4NQL A;  4A1O A;  1PL0 A;  2B3Z A;  2Z3J A;  4P9E A;  4BGD C;  1R5T A;  1WKQ A;  4I43 B;  4F3W A;  1R5X A;  4O8Y A;  3OJ6 A;  1AF2 A;  2KCQ A;  1M9N A;  4F7O A;  2A8N A;  4OWP B;  3RZV A;  4KIT C;  4O8Y B;  4LCO A;  4K1R A;  2OG4 A;  5GAO A;  1MQ0 A;  3EX8 A;  2P8R A;  2D5N A;  4PQT A;  4MSD A;  2HVW A;  3ZPG A;  2RPZ A;  4LCN A;  3ZEF B;  2B1I A;  1WN5 A;  4LD4 A;  4D10 F;  2ZNV A;  3R2N A;  2Z3I A;  3OCQ A;  4MSM A;  4LC5 A;  2B1G A;  4MSJ A;  3ZPC A;  2ZNR A;  5DCA J;  1CTU A;  3DMO A;  1RB7 A;  1UX1 A;  3DH1 A;  3E1U A;  4QFT A;  2O7P A;  2O95 A;  4MSQ A;  2OBC A;  2QLC A;  2P87 A;  1P4R A;  4ZFR A;  3BH1 A;  2D30 A;  4P9C A;  5CW6 A;  1OI0 A;  2HXV A;  2Z3G A;  2NX8 A;  1PKX A;  4WIF A;  2B3J A;  4LD2 A;  3VX8 A;  2FR5 A;  2G6V A;  5M52 C;  3ZZM A;  3RZU A;  1UX0 A;  1WWR A;  4HRW A;  1YSB A;  4OCL A;  2Z3H A;  4WIG A;  3SBG A;  4OCL B;  1G8M A;  4ZD5 A;  2NYT A;  1ZAB A;  4ZD4 A;  2G84 A;  1ALN A;  4O8X A;  1YSD A;  4OCM A;  1Z3A A;  4J6E A;  1TIY A;  1WN6 A;  1UAQ A;  4JXE A;  4HRQ A;  4EHI A;  2FR6 A;  1ZCZ A;  4EG2 A;  5C2O A;  4G3M A;  3B8F A;  2O96 A;  4OWP A;  2IU0 A;  4OCN A;  1OX7 A;  2HVV A;  1VQ2 A;  1P6O A;  4LCP A;  1OZ0 A;  3IJF X;  4E0Q A;  4OCN B;  1JTK A;  1UWZ A;  2KKS A;  2IU3 A;  3MPZ A;  5M59 B;  1VK9 A;  2O3K A;  4P9D A;  2W4L A;  3G8Q A;  4ILG C;  4O8X B;  4OCM B;  1THZ A;  1CTT A;  4ZFT A;  4GGM X; 
#chains in the Genus database with same CATH homology
 2PW9 A;  4MS7 A;  4NQL A;  2B3Z A;  2Z3J A;  4P9E A;  4BGD C;  1R5T A;  1WKQ A;  4I43 B;  4F3W A;  1R5X A;  4O8Y A;  3OJ6 A;  1AF2 A;  2KCQ A;  4F7O A;  2A8N A;  4OWP B;  3RZV A;  4KIT C;  4O8Y B;  4LCO A;  4K1R A;  2OG4 A;  5GAO A;  1MQ0 A;  3EX8 A;  2P8R A;  2D5N A;  4PQT A;  4MSD A;  2HVW A;  3ZPG A;  2RPZ A;  4LCN A;  3ZEF B;  1WN5 A;  4LD4 A;  4D10 F;  2ZNV A;  3R2N A;  2Z3I A;  3OCQ A;  4MSM A;  4LC5 A;  4MSJ A;  3ZPC A;  2ZNR A;  5DCA J;  1CTU A;  3DMO A;  1RB7 A;  1UX1 A;  3DH1 A;  3E1U A;  4QFT A;  2O7P A;  2O95 A;  4MSQ A;  2OBC A;  2QLC A;  2P87 A;  4ZFR A;  2D30 A;  4P9C A;  5CW6 A;  1OI0 A;  2HXV A;  2Z3G A;  2NX8 A;  4WIF A;  2B3J A;  4LD2 A;  2FR5 A;  2G6V A;  5M52 C;  3RZU A;  1UX0 A;  1WWR A;  4HRW A;  1YSB A;  4OCL A;  2Z3H A;  4WIG A;  3SBG A;  4OCL B;  4ZD5 A;  2NYT A;  1ZAB A;  4ZD4 A;  2G84 A;  1ALN A;  4O8X A;  1YSD A;  4OCM A;  1Z3A A;  1TIY A;  1WN6 A;  1UAQ A;  4JXE A;  4HRQ A;  2FR6 A;  4EG2 A;  5C2O A;  4G3M A;  3B8F A;  2O96 A;  4OWP A;  4OCN A;  1OX7 A;  2HVV A;  1VQ2 A;  1P6O A;  4LCP A;  3IJF X;  4E0Q A;  4OCN B;  1UWZ A;  1JTK A;  2KKS A;  3MPZ A;  5M59 B;  2O3K A;  4P9D A;  2W4L A;  3G8Q A;  4ILG C;  4O8X B;  4OCM B;  1CTT A;  4ZFT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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