2OG4A

Structure of an expanded jab1-mpn-like domain of splicing factor prp8p from yeast
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
249
structure length
249
Chain Sequence
SKNEWRKSAIANTLLYLRLKNIYVSADDFVEEQNVYVLPKNLLKKFIEISDVKIQVAAFIYGMSAKDHPKVKEIKTVVLVPQLGHVGSVQISNIPDIGDLPDTEGLELLGWIHTQTEELKFMAASEVATHSKLFADKKRDCIDISIFSTPGSVSLSAYNLTDEGYQWGEENKDIMNVLSEGFEPTFSTHAQLLLSDRITGNFIIPSGNVWNYTFMGTAFNQEGDYNFKYGIPLEFYNEMHRPVHFLQFS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa.
pubmed doi rcsb
molecule tags Protein binding
source organism Saccharomyces cerevisiae
molecule keywords Pre-mRNA-splicing factor 8
total genus 75
structure length 249
sequence length 249
ec nomenclature
pdb deposition date 2007-01-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.140.10 Alpha Beta 3-Layer(aba) Sandwich Cytidine Deaminase; domain 2 Cytidine Deaminase, domain 2 2og4A01
3G8QA 2OG4A 2FR5A 4K1RA 1WN5A 4MS7A 1VQ2A 2HVVA 4LCOA 1CTUA 4LD2A 3B8FA 4OCNA 2O7PA 1JTKA 4QFTA 3SBGA 4ZFRA 4O8YB 4OCMA 1TIYA 1WKQA 4OWPA 3ZPGA 4OCLA 3IJFX 4LD4A 5DCAJ 5M59B 4WIFA 4MSMA 2O96A 2Z3HA 2RPZA 2HXVA 1AF2A 4G3MA 4LCNA 4MSJA 1P6OA 3DMOA 1OX7A 4P9EA 4O8XB 2P8RA 2O3KA 3RZVA 4O8YA 2QLCA 4BGDC 4LC5A 2OBCA 5M52C 1Z3AA 2PW9A 1R5XA 3OCQA 4WIGA 1YSDA 2G84A 1WN6A 4LCPA 2D30A 2O95A 2Z3IA 4HRQA 4OCMB 2B3JA 4ILGC 5GAOA 2A8NA 1CTTA 2NYTA 2W4LA 4JXEA 4OCLB 4EG2A 2NX8A 2FR6A 4MSQA 2D5NA 4KITC 2P87A 3ZPCA 4ZD5A 2B3ZA 3EX8A 4PQTA 4F3WA 1UX1A 3E1UA 4O8XA 4E0QA 4P9CA 3OJ6A 4ZD4A 1RB7A 3DH1A 1UAQA 2HVWA 1OI0A 2Z3JA 4OCNB 4I43B 5C2OA 3RZUA 3MPZA 4NQLA 1WWRA 1MQ0A 1ZABA 2Z3GA 1UWZA 5CW6A 4OWPB 2ZNVA 4HRWA 2G6VA 2KCQA 2ZNRA 1ALNA 3R2NA 4F7OA 3ZEFB 4P9DA 4D10F 4ZFTA 2KKSA 1YSBA 1R5TA 4MSDA 1UX0A
chains in the Genus database with same CATH superfamily
3G8QA 2OG4A 2FR5A 4K1RA 1OZ0A 1WN5A 4MS7A 1VQ2A 2HVVA 4LCOA 1CTUA 4LD2A 3B8FA 4OCNA 2IU3A 2O7PA 1JTKA 4QFTA 3SBGA 1P4RA 4ZFRA 4O8YB 4OCMA 1TIYA 1WKQA 4OWPA 3ZPGA 4A1OA 4OCLA 1M9NA 3IJFX 4LD4A 5DCAJ 5M59B 4WIFA 2B1GA 4MSMA 2O96A 2Z3HA 2RPZA 2HXVA 1AF2A 4G3MA 1G8MA 3BH1A 4LCNA 4MSJA 1P6OA 3DMOA 1OX7A 1PL0A 4P9EA 4O8XB 2P8RA 2O3KA 3RZVA 4O8YA 2QLCA 1THZA 4BGDC 4LC5A 2B1IA 2OBCA 5M52C 1Z3AA 2IU0A 2PW9A 1R5XA 3OCQA 4WIGA 1YSDA 2G84A 1WN6A 4LCPA 2D30A 2O95A 2Z3IA 4HRQA 4J6EA 4OCMB 2B3JA 4ILGC 5GAOA 2A8NA 1CTTA 2NYTA 1PKXA 2W4LA 4JXEA 4OCLB 4EG2A 2NX8A 2FR6A 4MSQA 2D5NA 4KITC 2P87A 3ZPCA 4ZD5A 2B3ZA 3EX8A 4PQTA 4F3WA 1UX1A 3E1UA 4O8XA 1ZCZA 4E0QA 4P9CA 3OJ6A 4ZD4A 1RB7A 3DH1A 1UAQA 4GGMX 2HVWA 1OI0A 2Z3JA 4OCNB 4I43B 4EHIA 5C2OA 3RZUA 3MPZA 4NQLA 1WWRA 1MQ0A 1ZABA 2Z3GA 1UWZA 5CW6A 4OWPB 2ZNVA 4HRWA 2G6VA 2KCQA 2ZNRA 1ALNA 3R2NA 3ZZMA 4F7OA 3ZEFB 4P9DA 4D10F 4ZFTA 2KKSA 1YSBA 3VX8A 1R5TA 4MSDA 1VK9A 1UX0A
chains in the Genus database with same CATH topology
3G8QA 2OG4A 2FR5A 4K1RA 1WN5A 4MS7A 1VQ2A 2HVVA 4LCOA 1CTUA 4LD2A 3B8FA 4OCNA 2O7PA 1JTKA 4QFTA 3SBGA 4ZFRA 4O8YB 4OCMA 1TIYA 1WKQA 4OWPA 3ZPGA 4OCLA 3IJFX 4LD4A 5DCAJ 5M59B 4WIFA 4MSMA 2O96A 2Z3HA 2RPZA 2HXVA 1AF2A 4G3MA 4LCNA 4MSJA 1P6OA 3DMOA 1OX7A 4P9EA 4O8XB 2P8RA 2O3KA 3RZVA 4O8YA 2QLCA 4BGDC 4LC5A 2OBCA 5M52C 1Z3AA 2PW9A 1R5XA 3OCQA 4WIGA 1YSDA 2G84A 1WN6A 4LCPA 2D30A 2O95A 2Z3IA 4HRQA 4OCMB 2B3JA 4ILGC 5GAOA 2A8NA 1CTTA 2NYTA 2W4LA 4JXEA 4OCLB 4EG2A 2NX8A 2FR6A 4MSQA 2D5NA 4KITC 2P87A 3ZPCA 4ZD5A 2B3ZA 3EX8A 4PQTA 4F3WA 1UX1A 3E1UA 4O8XA 4E0QA 4P9CA 3OJ6A 4ZD4A 1RB7A 3DH1A 1UAQA 2HVWA 1OI0A 2Z3JA 4OCNB 4I43B 5C2OA 3RZUA 3MPZA 4NQLA 1WWRA 1MQ0A 1ZABA 2Z3GA 1UWZA 5CW6A 4OWPB 2ZNVA 4HRWA 2G6VA 2KCQA 2ZNRA 1ALNA 3R2NA 4F7OA 3ZEFB 4P9DA 4D10F 4ZFTA 2KKSA 1YSBA 1R5TA 4MSDA 1UX0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G8Q A;  2OG4 A;  2FR5 A;  4K1R A;  1WN5 A;  4MS7 A;  1VQ2 A;  2HVV A;  4LCO A;  1CTU A;  4LD2 A;  3B8F A;  4OCN A;  2O7P A;  1JTK A;  4QFT A;  3SBG A;  4ZFR A;  4O8Y B;  4OCM A;  1TIY A;  1WKQ A;  4OWP A;  3ZPG A;  4OCL A;  3IJF X;  4LD4 A;  5DCA J;  5M59 B;  4WIF A;  4MSM A;  2O96 A;  2Z3H A;  2RPZ A;  2HXV A;  1AF2 A;  4G3M A;  4LCN A;  4MSJ A;  1P6O A;  3DMO A;  1OX7 A;  4P9E A;  4O8X B;  2P8R A;  2O3K A;  3RZV A;  4O8Y A;  2QLC A;  4BGD C;  4LC5 A;  2OBC A;  5M52 C;  1Z3A A;  2PW9 A;  1R5X A;  3OCQ A;  4WIG A;  1YSD A;  2G84 A;  1WN6 A;  4LCP A;  2D30 A;  2O95 A;  2Z3I A;  4HRQ A;  4OCM B;  2B3J A;  4ILG C;  5GAO A;  2A8N A;  1CTT A;  2NYT A;  2W4L A;  4JXE A;  4OCL B;  4EG2 A;  2NX8 A;  2FR6 A;  4MSQ A;  2D5N A;  4KIT C;  2P87 A;  3ZPC A;  4ZD5 A;  2B3Z A;  3EX8 A;  4PQT A;  4F3W A;  1UX1 A;  3E1U A;  4O8X A;  4E0Q A;  4P9C A;  3OJ6 A;  4ZD4 A;  1RB7 A;  3DH1 A;  1UAQ A;  2HVW A;  1OI0 A;  2Z3J A;  4OCN B;  4I43 B;  5C2O A;  3RZU A;  3MPZ A;  4NQL A;  1WWR A;  1MQ0 A;  1ZAB A;  2Z3G A;  1UWZ A;  5CW6 A;  4OWP B;  2ZNV A;  4HRW A;  2G6V A;  2KCQ A;  2ZNR A;  1ALN A;  3R2N A;  4F7O A;  3ZEF B;  4P9D A;  4D10 F;  4ZFT A;  2KKS A;  1YSB A;  1R5T A;  4MSD A;  1UX0 A; 
#chains in the Genus database with same CATH topology
 3G8Q A;  2OG4 A;  2FR5 A;  4K1R A;  1OZ0 A;  1WN5 A;  4MS7 A;  1VQ2 A;  2HVV A;  4LCO A;  1CTU A;  4LD2 A;  3B8F A;  4OCN A;  2IU3 A;  2O7P A;  1JTK A;  4QFT A;  3SBG A;  1P4R A;  4ZFR A;  4O8Y B;  4OCM A;  1TIY A;  1WKQ A;  4OWP A;  3ZPG A;  4A1O A;  4OCL A;  1M9N A;  3IJF X;  4LD4 A;  5DCA J;  5M59 B;  4WIF A;  2B1G A;  4MSM A;  2O96 A;  2Z3H A;  2RPZ A;  2HXV A;  1AF2 A;  4G3M A;  1G8M A;  3BH1 A;  4LCN A;  4MSJ A;  1P6O A;  3DMO A;  1OX7 A;  1PL0 A;  4P9E A;  4O8X B;  2P8R A;  2O3K A;  3RZV A;  4O8Y A;  2QLC A;  1THZ A;  4BGD C;  4LC5 A;  2B1I A;  2OBC A;  5M52 C;  1Z3A A;  2IU0 A;  2PW9 A;  1R5X A;  3OCQ A;  4WIG A;  1YSD A;  2G84 A;  1WN6 A;  4LCP A;  2D30 A;  2O95 A;  2Z3I A;  4HRQ A;  4J6E A;  4OCM B;  2B3J A;  4ILG C;  5GAO A;  2A8N A;  1CTT A;  2NYT A;  1PKX A;  2W4L A;  4JXE A;  4OCL B;  4EG2 A;  2NX8 A;  2FR6 A;  4MSQ A;  2D5N A;  4KIT C;  2P87 A;  3ZPC A;  4ZD5 A;  2B3Z A;  3EX8 A;  4PQT A;  4F3W A;  1UX1 A;  3E1U A;  4O8X A;  1ZCZ A;  4E0Q A;  4P9C A;  3OJ6 A;  4ZD4 A;  1RB7 A;  3DH1 A;  1UAQ A;  4GGM X;  2HVW A;  1OI0 A;  2Z3J A;  4OCN B;  4I43 B;  4EHI A;  5C2O A;  3RZU A;  3MPZ A;  4NQL A;  1WWR A;  1MQ0 A;  1ZAB A;  2Z3G A;  1UWZ A;  5CW6 A;  4OWP B;  2ZNV A;  4HRW A;  2G6V A;  2KCQ A;  2ZNR A;  1ALN A;  3R2N A;  3ZZM A;  4F7O A;  3ZEF B;  4P9D A;  4D10 F;  4ZFT A;  2KKS A;  1YSB A;  3VX8 A;  1R5T A;  4MSD A;  1VK9 A;  1UX0 A; 
#chains in the Genus database with same CATH homology
 3G8Q A;  2OG4 A;  2FR5 A;  4K1R A;  1WN5 A;  4MS7 A;  1VQ2 A;  2HVV A;  4LCO A;  1CTU A;  4LD2 A;  3B8F A;  4OCN A;  2O7P A;  1JTK A;  4QFT A;  3SBG A;  4ZFR A;  4O8Y B;  4OCM A;  1TIY A;  1WKQ A;  4OWP A;  3ZPG A;  4OCL A;  3IJF X;  4LD4 A;  5DCA J;  5M59 B;  4WIF A;  4MSM A;  2O96 A;  2Z3H A;  2RPZ A;  2HXV A;  1AF2 A;  4G3M A;  4LCN A;  4MSJ A;  1P6O A;  3DMO A;  1OX7 A;  4P9E A;  4O8X B;  2P8R A;  2O3K A;  3RZV A;  4O8Y A;  2QLC A;  4BGD C;  4LC5 A;  2OBC A;  5M52 C;  1Z3A A;  2PW9 A;  1R5X A;  3OCQ A;  4WIG A;  1YSD A;  2G84 A;  1WN6 A;  4LCP A;  2D30 A;  2O95 A;  2Z3I A;  4HRQ A;  4OCM B;  2B3J A;  4ILG C;  5GAO A;  2A8N A;  1CTT A;  2NYT A;  2W4L A;  4JXE A;  4OCL B;  4EG2 A;  2NX8 A;  2FR6 A;  4MSQ A;  2D5N A;  4KIT C;  2P87 A;  3ZPC A;  4ZD5 A;  2B3Z A;  3EX8 A;  4PQT A;  4F3W A;  1UX1 A;  3E1U A;  4O8X A;  4E0Q A;  4P9C A;  3OJ6 A;  4ZD4 A;  1RB7 A;  3DH1 A;  1UAQ A;  2HVW A;  1OI0 A;  2Z3J A;  4OCN B;  4I43 B;  5C2O A;  3RZU A;  3MPZ A;  4NQL A;  1WWR A;  1MQ0 A;  1ZAB A;  2Z3G A;  1UWZ A;  5CW6 A;  4OWP B;  2ZNV A;  4HRW A;  2G6V A;  2KCQ A;  2ZNR A;  1ALN A;  3R2N A;  4F7O A;  3ZEF B;  4P9D A;  4D10 F;  4ZFT A;  2KKS A;  1YSB A;  1R5T A;  4MSD A;  1UX0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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