2P87A

Crystal structure of the c-terminal domain of c. elegans pre-mrna splicing factor prp8
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
246
structure length
246
Chain Sequence
SRTEWRVRAISSTNLHLRTQHIYVNSDDVKDTGYTYILPKNILKKFITISDLRTQIAGFMYGVSPPDNPQVKEIRCIVLVPQTGSHQQVNLPTQLPDHELLRDFEPLGWMHTQPNELPQLSPQDVTTHAKLLTDNISWDGEKTVMITCSFTPGSVSLTAYKLTPSGYEWGKANTDKGNNPKGYMPTHYEKVQMLLSDRFLGYFMVPSNGVWNYNFQGQRWSPAMKFDVCLSNPKEYYHEDHRPVHF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants
pubmed doi rcsb
molecule tags Splicing
source organism Caenorhabditis elegans
molecule keywords Pre-mRNA-splicing factor Prp8
total genus 69
structure length 246
sequence length 246
ec nomenclature
pdb deposition date 2007-03-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01398 JAB JAB1/Mov34/MPN/PAD-1 ubiquitin protease
A PF08084 PROCT PROCT (NUC072) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.140.10 Alpha Beta 3-Layer(aba) Sandwich Cytidine Deaminase; domain 2 Cytidine Deaminase, domain 2 2p87A01
1OX7A 3E1UA 1JTKA 4K1RA 4MSMA 2OG4A 4NQLA 4PQTA 2RPZA 2Z3JA 1MQ0A 5M52C 1R5TA 2FR6A 2HVVA 2A8NA 2ZNVA 2HXVA 3ZEFB 4O8XA 4LD2A 4KITC 4LCOA 4P9DA 4LCPA 1AF2A 3B8FA 2NX8A 3SBGA 4MSJA 1P6OA 2KKSA 4O8XB 3OJ6A 5DCAJ 4P9EA 1ZABA 3IJFX 4BGDC 5C2OA 5CW6A 1RB7A 1WN5A 4OCNB 4G3MA 2W4LA 4LD4A 4WIGA 4MSQA 4E0QA 2P8RA 2D5NA 4OCLA 2ZNRA 4EG2A 5GAOA 4OCMA 2P87A 3R2NA 3DH1A 3MPZA 1R5XA 2O96A 2PW9A 3EX8A 4OCLB 3ZPGA 4D10F 1UWZA 2NYTA 3G8QA 4OCNA 4OCMB 4LCNA 4F3WA 4P9CA 2QLCA 2O95A 1YSBA 2O3KA 4ZFTA 1ALNA 1UX1A 4OWPA 4O8YA 3DMOA 2D30A 4HRQA 2G6VA 4LC5A 1VQ2A 2FR5A 2Z3GA 1WKQA 1Z3AA 3OCQA 4WIFA 4OWPB 4O8YB 5M59B 2O7PA 4F7OA 4ILGC 4HRWA 3ZPCA 2HVWA 1OI0A 4MS7A 4ZFRA 3RZVA 4QFTA 1CTTA 1WWRA 4JXEA 1CTUA 1UX0A 4ZD5A 1UAQA 1TIYA 1WN6A 2G84A 2Z3IA 2B3ZA 2OBCA 2Z3HA 2B3JA 2KCQA 1YSDA 3RZUA 4MSDA 4I43B 4ZD4A
chains in the Genus database with same CATH superfamily
1OX7A 3E1UA 1JTKA 4K1RA 4MSMA 2OG4A 4NQLA 1OZ0A 4PQTA 2RPZA 1P4RA 2Z3JA 1MQ0A 5M52C 1G8MA 1R5TA 2FR6A 2HVVA 2A8NA 2B1GA 2ZNVA 2IU3A 2HXVA 3ZEFB 2B1IA 4O8XA 4LD2A 4KITC 4LCOA 4P9DA 4LCPA 1AF2A 3ZZMA 3B8FA 1ZCZA 2NX8A 3SBGA 4MSJA 1P6OA 2KKSA 4O8XB 4J6EA 3OJ6A 3VX8A 5DCAJ 4P9EA 4EHIA 4A1OA 1ZABA 3IJFX 4BGDC 5C2OA 3BH1A 5CW6A 1RB7A 1WN5A 4OCNB 1PKXA 4G3MA 2W4LA 4LD4A 4WIGA 4MSQA 4E0QA 2P8RA 2D5NA 4OCLA 1M9NA 2ZNRA 4EG2A 5GAOA 4OCMA 2P87A 3R2NA 3DH1A 3MPZA 1R5XA 2O96A 2PW9A 3EX8A 4OCLB 3ZPGA 4D10F 1UWZA 2NYTA 3G8QA 4OCNA 4OCMB 4GGMX 4LCNA 4F3WA 1PL0A 4P9CA 2QLCA 2O95A 1YSBA 2O3KA 4ZFTA 2IU0A 1ALNA 1UX1A 4OWPA 4O8YA 3DMOA 2D30A 4HRQA 2G6VA 4LC5A 1VQ2A 2FR5A 2Z3GA 1WKQA 1Z3AA 3OCQA 4WIFA 4OWPB 4O8YB 5M59B 1THZA 2O7PA 4F7OA 4HRWA 4ILGC 3ZPCA 2HVWA 1OI0A 4MS7A 4ZFRA 3RZVA 4QFTA 1CTTA 1WWRA 1VK9A 4JXEA 1CTUA 1UX0A 4ZD5A 1UAQA 1TIYA 1WN6A 2G84A 2Z3IA 2B3ZA 2OBCA 2Z3HA 2B3JA 2KCQA 1YSDA 3RZUA 4MSDA 4I43B 4ZD4A
chains in the Genus database with same CATH topology
1OX7A 3E1UA 1JTKA 4K1RA 4MSMA 2OG4A 4NQLA 4PQTA 2RPZA 2Z3JA 1MQ0A 5M52C 1R5TA 2FR6A 2HVVA 2A8NA 2ZNVA 2HXVA 3ZEFB 4O8XA 4LD2A 4KITC 4LCOA 4P9DA 4LCPA 1AF2A 3B8FA 2NX8A 3SBGA 4MSJA 1P6OA 2KKSA 4O8XB 3OJ6A 5DCAJ 4P9EA 1ZABA 3IJFX 4BGDC 5C2OA 5CW6A 1RB7A 1WN5A 4OCNB 4G3MA 2W4LA 4LD4A 4WIGA 4MSQA 4E0QA 2P8RA 2D5NA 4OCLA 2ZNRA 4EG2A 5GAOA 4OCMA 2P87A 3R2NA 3DH1A 3MPZA 1R5XA 2O96A 2PW9A 3EX8A 4OCLB 3ZPGA 4D10F 1UWZA 2NYTA 3G8QA 4OCNA 4OCMB 4LCNA 4F3WA 4P9CA 2QLCA 2O95A 1YSBA 2O3KA 4ZFTA 1ALNA 1UX1A 4OWPA 4O8YA 3DMOA 2D30A 4HRQA 2G6VA 4LC5A 1VQ2A 2FR5A 2Z3GA 1WKQA 1Z3AA 3OCQA 4WIFA 4OWPB 4O8YB 5M59B 2O7PA 4F7OA 4ILGC 4HRWA 3ZPCA 2HVWA 1OI0A 4MS7A 4ZFRA 3RZVA 4QFTA 1CTTA 1WWRA 4JXEA 1CTUA 1UX0A 4ZD5A 1UAQA 1TIYA 1WN6A 2G84A 2Z3IA 2B3ZA 2OBCA 2Z3HA 2B3JA 2KCQA 1YSDA 3RZUA 4MSDA 4I43B 4ZD4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OX7 A;  3E1U A;  1JTK A;  4K1R A;  4MSM A;  2OG4 A;  4NQL A;  4PQT A;  2RPZ A;  2Z3J A;  1MQ0 A;  5M52 C;  1R5T A;  2FR6 A;  2HVV A;  2A8N A;  2ZNV A;  2HXV A;  3ZEF B;  4O8X A;  4LD2 A;  4KIT C;  4LCO A;  4P9D A;  4LCP A;  1AF2 A;  3B8F A;  2NX8 A;  3SBG A;  4MSJ A;  1P6O A;  2KKS A;  4O8X B;  3OJ6 A;  5DCA J;  4P9E A;  1ZAB A;  3IJF X;  4BGD C;  5C2O A;  5CW6 A;  1RB7 A;  1WN5 A;  4OCN B;  4G3M A;  2W4L A;  4LD4 A;  4WIG A;  4MSQ A;  4E0Q A;  2P8R A;  2D5N A;  4OCL A;  2ZNR A;  4EG2 A;  5GAO A;  4OCM A;  2P87 A;  3R2N A;  3DH1 A;  3MPZ A;  1R5X A;  2O96 A;  2PW9 A;  3EX8 A;  4OCL B;  3ZPG A;  4D10 F;  1UWZ A;  2NYT A;  3G8Q A;  4OCN A;  4OCM B;  4LCN A;  4F3W A;  4P9C A;  2QLC A;  2O95 A;  1YSB A;  2O3K A;  4ZFT A;  1ALN A;  1UX1 A;  4OWP A;  4O8Y A;  3DMO A;  2D30 A;  4HRQ A;  2G6V A;  4LC5 A;  1VQ2 A;  2FR5 A;  2Z3G A;  1WKQ A;  1Z3A A;  3OCQ A;  4WIF A;  4OWP B;  4O8Y B;  5M59 B;  2O7P A;  4F7O A;  4ILG C;  4HRW A;  3ZPC A;  2HVW A;  1OI0 A;  4MS7 A;  4ZFR A;  3RZV A;  4QFT A;  1CTT A;  1WWR A;  4JXE A;  1CTU A;  1UX0 A;  4ZD5 A;  1UAQ A;  1TIY A;  1WN6 A;  2G84 A;  2Z3I A;  2B3Z A;  2OBC A;  2Z3H A;  2B3J A;  2KCQ A;  1YSD A;  3RZU A;  4MSD A;  4I43 B;  4ZD4 A; 
#chains in the Genus database with same CATH topology
 1OX7 A;  3E1U A;  1JTK A;  4K1R A;  4MSM A;  2OG4 A;  4NQL A;  1OZ0 A;  4PQT A;  2RPZ A;  1P4R A;  2Z3J A;  1MQ0 A;  5M52 C;  1G8M A;  1R5T A;  2FR6 A;  2HVV A;  2A8N A;  2B1G A;  2ZNV A;  2IU3 A;  2HXV A;  3ZEF B;  2B1I A;  4O8X A;  4LD2 A;  4KIT C;  4LCO A;  4P9D A;  4LCP A;  1AF2 A;  3ZZM A;  3B8F A;  1ZCZ A;  2NX8 A;  3SBG A;  4MSJ A;  1P6O A;  2KKS A;  4O8X B;  4J6E A;  3OJ6 A;  3VX8 A;  5DCA J;  4P9E A;  4EHI A;  4A1O A;  1ZAB A;  3IJF X;  4BGD C;  5C2O A;  3BH1 A;  5CW6 A;  1RB7 A;  1WN5 A;  4OCN B;  1PKX A;  4G3M A;  2W4L A;  4LD4 A;  4WIG A;  4MSQ A;  4E0Q A;  2P8R A;  2D5N A;  4OCL A;  1M9N A;  2ZNR A;  4EG2 A;  5GAO A;  4OCM A;  2P87 A;  3R2N A;  3DH1 A;  3MPZ A;  1R5X A;  2O96 A;  2PW9 A;  3EX8 A;  4OCL B;  3ZPG A;  4D10 F;  1UWZ A;  2NYT A;  3G8Q A;  4OCN A;  4OCM B;  4GGM X;  4LCN A;  4F3W A;  1PL0 A;  4P9C A;  2QLC A;  2O95 A;  1YSB A;  2O3K A;  4ZFT A;  2IU0 A;  1ALN A;  1UX1 A;  4OWP A;  4O8Y A;  3DMO A;  2D30 A;  4HRQ A;  2G6V A;  4LC5 A;  1VQ2 A;  2FR5 A;  2Z3G A;  1WKQ A;  1Z3A A;  3OCQ A;  4WIF A;  4OWP B;  4O8Y B;  5M59 B;  1THZ A;  2O7P A;  4F7O A;  4HRW A;  4ILG C;  3ZPC A;  2HVW A;  1OI0 A;  4MS7 A;  4ZFR A;  3RZV A;  4QFT A;  1CTT A;  1WWR A;  1VK9 A;  4JXE A;  1CTU A;  1UX0 A;  4ZD5 A;  1UAQ A;  1TIY A;  1WN6 A;  2G84 A;  2Z3I A;  2B3Z A;  2OBC A;  2Z3H A;  2B3J A;  2KCQ A;  1YSD A;  3RZU A;  4MSD A;  4I43 B;  4ZD4 A; 
#chains in the Genus database with same CATH homology
 1OX7 A;  3E1U A;  1JTK A;  4K1R A;  4MSM A;  2OG4 A;  4NQL A;  4PQT A;  2RPZ A;  2Z3J A;  1MQ0 A;  5M52 C;  1R5T A;  2FR6 A;  2HVV A;  2A8N A;  2ZNV A;  2HXV A;  3ZEF B;  4O8X A;  4LD2 A;  4KIT C;  4LCO A;  4P9D A;  4LCP A;  1AF2 A;  3B8F A;  2NX8 A;  3SBG A;  4MSJ A;  1P6O A;  2KKS A;  4O8X B;  3OJ6 A;  5DCA J;  4P9E A;  1ZAB A;  3IJF X;  4BGD C;  5C2O A;  5CW6 A;  1RB7 A;  1WN5 A;  4OCN B;  4G3M A;  2W4L A;  4LD4 A;  4WIG A;  4MSQ A;  4E0Q A;  2P8R A;  2D5N A;  4OCL A;  2ZNR A;  4EG2 A;  5GAO A;  4OCM A;  2P87 A;  3R2N A;  3DH1 A;  3MPZ A;  1R5X A;  2O96 A;  2PW9 A;  3EX8 A;  4OCL B;  3ZPG A;  4D10 F;  1UWZ A;  2NYT A;  3G8Q A;  4OCN A;  4OCM B;  4LCN A;  4F3W A;  4P9C A;  2QLC A;  2O95 A;  1YSB A;  2O3K A;  4ZFT A;  1ALN A;  1UX1 A;  4OWP A;  4O8Y A;  3DMO A;  2D30 A;  4HRQ A;  2G6V A;  4LC5 A;  1VQ2 A;  2FR5 A;  2Z3G A;  1WKQ A;  1Z3A A;  3OCQ A;  4WIF A;  4OWP B;  4O8Y B;  5M59 B;  2O7P A;  4F7O A;  4ILG C;  4HRW A;  3ZPC A;  2HVW A;  1OI0 A;  4MS7 A;  4ZFR A;  3RZV A;  4QFT A;  1CTT A;  1WWR A;  4JXE A;  1CTU A;  1UX0 A;  4ZD5 A;  1UAQ A;  1TIY A;  1WN6 A;  2G84 A;  2Z3I A;  2B3Z A;  2OBC A;  2Z3H A;  2B3J A;  2KCQ A;  1YSD A;  3RZU A;  4MSD A;  4I43 B;  4ZD4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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