2W4LA

Human dcmp deaminase
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
164
structure length
160
Chain Sequence
CKKRDDYLEWPEYFMAVAFLSAQRSKDPNSQVGACIVNSENKIVGIGYNGMPNGCSDDVLPWRRTAENKLDTKYPYVCHAELNAIMNDVKGCSMYVALFPCNECAKLIIQAGIKEVIFMSDKYHDSDEATAARLLFNMAGVTFRKFIPKCSKIVIDFDSI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of Human Dcmp Deaminase
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords DEOXYCYTIDYLATE DEAMINASE
total genus 39
structure length 160
sequence length 164
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.5.4.12: dCMP deaminase.
pdb deposition date 2008-11-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00383 dCMP_cyt_deam_1 Cytidine and deoxycytidylate deaminase zinc-binding region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.140.10 Alpha Beta 3-Layer(aba) Sandwich Cytidine Deaminase; domain 2 Cytidine Deaminase, domain 2 2w4lA00
4MSQA 4P9CA 1OX7A 4OCMA 1OI0A 1WN5A 4MSMA 3SBGA 2Z3GA 1WKQA 4ZD4A 4K1RA 4LCOA 4OCMB 2FR6A 4ZFTA 1ZABA 1RB7A 2G6VA 2FR5A 1UX0A 2O7PA 5CW6A 4BGDC 1UWZA 4LC5A 4LCPA 2KCQA 4P9EA 1R5TA 2P8RA 2A8NA 5M59B 3ZPGA 2HVWA 3G8QA 4I43B 2RPZA 4OWPB 2O95A 4JXEA 5C2OA 4MSDA 2D5NA 4O8YB 2ZNVA 4LD4A 4F7OA 3RZUA 2ZNRA 2NYTA 4HRQA 4O8XA 4G3MA 5M52C 3IJFX 3DH1A 1ALNA 3B8FA 5DCAJ 2P87A 1MQ0A 3DMOA 1VQ2A 4MSJA 2Z3HA 4O8XB 2O3KA 2D30A 2QLCA 3OJ6A 4OCLA 1AF2A 2O96A 4WIFA 1UAQA 2HXVA 2B3ZA 3E1UA 4PQTA 2OBCA 3EX8A 4LCNA 4WIGA 4ZFRA 1R5XA 1UX1A 1TIYA 4ILGC 5GAOA 1JTKA 1P6OA 1Z3AA 1CTTA 3ZEFB 4D10F 2B3JA 4F3WA 1WN6A 2PW9A 1YSBA 1WWRA 3RZVA 4ZD5A 4E0QA 3OCQA 3MPZA 4EG2A 4KITC 4NQLA 2G84A 2OG4A 2HVVA 4LD2A 4OCNA 2W4LA 1CTUA 3R2NA 2KKSA 2Z3IA 2NX8A 3ZPCA 2Z3JA 4P9DA 4MS7A 4HRWA 1YSDA 4OCLB 4QFTA 4OWPA 4OCNB 4O8YA
chains in the Genus database with same CATH superfamily
4MSQA 4P9CA 2B1GA 2IU3A 1OX7A 4OCMA 1OI0A 1WN5A 4MSMA 3SBGA 2Z3GA 1PL0A 1WKQA 4ZD4A 4K1RA 4LCOA 4OCMB 2B1IA 2FR6A 4ZFTA 1ZABA 1RB7A 2G6VA 2FR5A 1UX0A 2O7PA 5CW6A 4BGDC 1UWZA 4LC5A 4LCPA 2KCQA 4P9EA 1R5TA 2P8RA 2A8NA 5M59B 3VX8A 3ZPGA 2HVWA 3BH1A 3G8QA 4I43B 2RPZA 1PKXA 4OWPB 2O95A 4JXEA 1OZ0A 5C2OA 4MSDA 2D5NA 4O8YB 2ZNVA 4LD4A 4F7OA 3RZUA 2ZNRA 2NYTA 1G8MA 4HRQA 4O8XA 4G3MA 5M52C 3IJFX 3DH1A 1ALNA 3B8FA 5DCAJ 1M9NA 2P87A 1MQ0A 2IU0A 3DMOA 1VQ2A 4MSJA 2Z3HA 4O8XB 2O3KA 2D30A 2QLCA 3OJ6A 4OCLA 1AF2A 2O96A 4WIFA 1UAQA 2HXVA 2B3ZA 3E1UA 4PQTA 2OBCA 3EX8A 4LCNA 1THZA 4WIGA 4EHIA 4ZFRA 1ZCZA 1P4RA 1R5XA 1TIYA 1UX1A 4ILGC 5GAOA 1JTKA 1VK9A 1P6OA 1Z3AA 1CTTA 3ZZMA 4D10F 3ZEFB 2B3JA 4F3WA 1WN6A 2PW9A 1YSBA 1WWRA 3RZVA 4ZD5A 4E0QA 3OCQA 3MPZA 4GGMX 4EG2A 4KITC 4NQLA 2G84A 2OG4A 2HVVA 4J6EA 4LD2A 4OCNA 2W4LA 4A1OA 1CTUA 3R2NA 2KKSA 2Z3IA 2NX8A 3ZPCA 2Z3JA 4P9DA 4MS7A 4HRWA 1YSDA 4OCLB 4QFTA 4OWPA 4OCNB 4O8YA
chains in the Genus database with same CATH topology
4MSQA 4P9CA 1OX7A 4OCMA 1OI0A 1WN5A 4MSMA 3SBGA 2Z3GA 1WKQA 4ZD4A 4K1RA 4LCOA 4OCMB 2FR6A 4ZFTA 1ZABA 1RB7A 2G6VA 2FR5A 1UX0A 2O7PA 5CW6A 4BGDC 1UWZA 4LC5A 4LCPA 2KCQA 4P9EA 1R5TA 2P8RA 2A8NA 5M59B 3ZPGA 2HVWA 3G8QA 4I43B 2RPZA 4OWPB 2O95A 4JXEA 5C2OA 4MSDA 2D5NA 4O8YB 2ZNVA 4LD4A 4F7OA 3RZUA 2ZNRA 2NYTA 4HRQA 4O8XA 4G3MA 5M52C 3IJFX 3DH1A 1ALNA 3B8FA 5DCAJ 2P87A 1MQ0A 3DMOA 1VQ2A 4MSJA 2Z3HA 4O8XB 2O3KA 2D30A 2QLCA 3OJ6A 4OCLA 1AF2A 2O96A 4WIFA 1UAQA 2HXVA 2B3ZA 3E1UA 4PQTA 2OBCA 3EX8A 4LCNA 4WIGA 4ZFRA 1R5XA 1UX1A 1TIYA 4ILGC 5GAOA 1JTKA 1P6OA 1Z3AA 1CTTA 3ZEFB 4D10F 2B3JA 4F3WA 1WN6A 2PW9A 1YSBA 1WWRA 3RZVA 4ZD5A 4E0QA 3OCQA 3MPZA 4EG2A 4KITC 4NQLA 2G84A 2OG4A 2HVVA 4LD2A 4OCNA 2W4LA 1CTUA 3R2NA 2KKSA 2Z3IA 2NX8A 3ZPCA 2Z3JA 4P9DA 4MS7A 4HRWA 1YSDA 4OCLB 4QFTA 4OWPA 4OCNB 4O8YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MSQ A;  4P9C A;  1OX7 A;  4OCM A;  1OI0 A;  1WN5 A;  4MSM A;  3SBG A;  2Z3G A;  1WKQ A;  4ZD4 A;  4K1R A;  4LCO A;  4OCM B;  2FR6 A;  4ZFT A;  1ZAB A;  1RB7 A;  2G6V A;  2FR5 A;  1UX0 A;  2O7P A;  5CW6 A;  4BGD C;  1UWZ A;  4LC5 A;  4LCP A;  2KCQ A;  4P9E A;  1R5T A;  2P8R A;  2A8N A;  5M59 B;  3ZPG A;  2HVW A;  3G8Q A;  4I43 B;  2RPZ A;  4OWP B;  2O95 A;  4JXE A;  5C2O A;  4MSD A;  2D5N A;  4O8Y B;  2ZNV A;  4LD4 A;  4F7O A;  3RZU A;  2ZNR A;  2NYT A;  4HRQ A;  4O8X A;  4G3M A;  5M52 C;  3IJF X;  3DH1 A;  1ALN A;  3B8F A;  5DCA J;  2P87 A;  1MQ0 A;  3DMO A;  1VQ2 A;  4MSJ A;  2Z3H A;  4O8X B;  2O3K A;  2D30 A;  2QLC A;  3OJ6 A;  4OCL A;  1AF2 A;  2O96 A;  4WIF A;  1UAQ A;  2HXV A;  2B3Z A;  3E1U A;  4PQT A;  2OBC A;  3EX8 A;  4LCN A;  4WIG A;  4ZFR A;  1R5X A;  1UX1 A;  1TIY A;  4ILG C;  5GAO A;  1JTK A;  1P6O A;  1Z3A A;  1CTT A;  3ZEF B;  4D10 F;  2B3J A;  4F3W A;  1WN6 A;  2PW9 A;  1YSB A;  1WWR A;  3RZV A;  4ZD5 A;  4E0Q A;  3OCQ A;  3MPZ A;  4EG2 A;  4KIT C;  4NQL A;  2G84 A;  2OG4 A;  2HVV A;  4LD2 A;  4OCN A;  2W4L A;  1CTU A;  3R2N A;  2KKS A;  2Z3I A;  2NX8 A;  3ZPC A;  2Z3J A;  4P9D A;  4MS7 A;  4HRW A;  1YSD A;  4OCL B;  4QFT A;  4OWP A;  4OCN B;  4O8Y A; 
#chains in the Genus database with same CATH topology
 4MSQ A;  4P9C A;  2B1G A;  2IU3 A;  1OX7 A;  4OCM A;  1OI0 A;  1WN5 A;  4MSM A;  3SBG A;  2Z3G A;  1PL0 A;  1WKQ A;  4ZD4 A;  4K1R A;  4LCO A;  4OCM B;  2B1I A;  2FR6 A;  4ZFT A;  1ZAB A;  1RB7 A;  2G6V A;  2FR5 A;  1UX0 A;  2O7P A;  5CW6 A;  4BGD C;  1UWZ A;  4LC5 A;  4LCP A;  2KCQ A;  4P9E A;  1R5T A;  2P8R A;  2A8N A;  5M59 B;  3VX8 A;  3ZPG A;  2HVW A;  3BH1 A;  3G8Q A;  4I43 B;  2RPZ A;  1PKX A;  4OWP B;  2O95 A;  4JXE A;  1OZ0 A;  5C2O A;  4MSD A;  2D5N A;  4O8Y B;  2ZNV A;  4LD4 A;  4F7O A;  3RZU A;  2ZNR A;  2NYT A;  1G8M A;  4HRQ A;  4O8X A;  4G3M A;  5M52 C;  3IJF X;  3DH1 A;  1ALN A;  3B8F A;  5DCA J;  1M9N A;  2P87 A;  1MQ0 A;  2IU0 A;  3DMO A;  1VQ2 A;  4MSJ A;  2Z3H A;  4O8X B;  2O3K A;  2D30 A;  2QLC A;  3OJ6 A;  4OCL A;  1AF2 A;  2O96 A;  4WIF A;  1UAQ A;  2HXV A;  2B3Z A;  3E1U A;  4PQT A;  2OBC A;  3EX8 A;  4LCN A;  1THZ A;  4WIG A;  4EHI A;  4ZFR A;  1ZCZ A;  1P4R A;  1R5X A;  1TIY A;  1UX1 A;  4ILG C;  5GAO A;  1JTK A;  1VK9 A;  1P6O A;  1Z3A A;  1CTT A;  3ZZM A;  4D10 F;  3ZEF B;  2B3J A;  4F3W A;  1WN6 A;  2PW9 A;  1YSB A;  1WWR A;  3RZV A;  4ZD5 A;  4E0Q A;  3OCQ A;  3MPZ A;  4GGM X;  4EG2 A;  4KIT C;  4NQL A;  2G84 A;  2OG4 A;  2HVV A;  4J6E A;  4LD2 A;  4OCN A;  2W4L A;  4A1O A;  1CTU A;  3R2N A;  2KKS A;  2Z3I A;  2NX8 A;  3ZPC A;  2Z3J A;  4P9D A;  4MS7 A;  4HRW A;  1YSD A;  4OCL B;  4QFT A;  4OWP A;  4OCN B;  4O8Y A; 
#chains in the Genus database with same CATH homology
 4MSQ A;  4P9C A;  1OX7 A;  4OCM A;  1OI0 A;  1WN5 A;  4MSM A;  3SBG A;  2Z3G A;  1WKQ A;  4ZD4 A;  4K1R A;  4LCO A;  4OCM B;  2FR6 A;  4ZFT A;  1ZAB A;  1RB7 A;  2G6V A;  2FR5 A;  1UX0 A;  2O7P A;  5CW6 A;  4BGD C;  1UWZ A;  4LC5 A;  4LCP A;  2KCQ A;  4P9E A;  1R5T A;  2P8R A;  2A8N A;  5M59 B;  3ZPG A;  2HVW A;  3G8Q A;  4I43 B;  2RPZ A;  4OWP B;  2O95 A;  4JXE A;  5C2O A;  4MSD A;  2D5N A;  4O8Y B;  2ZNV A;  4LD4 A;  4F7O A;  3RZU A;  2ZNR A;  2NYT A;  4HRQ A;  4O8X A;  4G3M A;  5M52 C;  3IJF X;  3DH1 A;  1ALN A;  3B8F A;  5DCA J;  2P87 A;  1MQ0 A;  3DMO A;  1VQ2 A;  4MSJ A;  2Z3H A;  4O8X B;  2O3K A;  2D30 A;  2QLC A;  3OJ6 A;  4OCL A;  1AF2 A;  2O96 A;  4WIF A;  1UAQ A;  2HXV A;  2B3Z A;  3E1U A;  4PQT A;  2OBC A;  3EX8 A;  4LCN A;  4WIG A;  4ZFR A;  1R5X A;  1UX1 A;  1TIY A;  4ILG C;  5GAO A;  1JTK A;  1P6O A;  1Z3A A;  1CTT A;  3ZEF B;  4D10 F;  2B3J A;  4F3W A;  1WN6 A;  2PW9 A;  1YSB A;  1WWR A;  3RZV A;  4ZD5 A;  4E0Q A;  3OCQ A;  3MPZ A;  4EG2 A;  4KIT C;  4NQL A;  2G84 A;  2OG4 A;  2HVV A;  4LD2 A;  4OCN A;  2W4L A;  1CTU A;  3R2N A;  2KKS A;  2Z3I A;  2NX8 A;  3ZPC A;  2Z3J A;  4P9D A;  4MS7 A;  4HRW A;  1YSD A;  4OCL B;  4QFT A;  4OWP A;  4OCN B;  4O8Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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