4E0QA

Crystal structure of mpn domain from cop9 signalosome
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
134
structure length
121
Chain Sequence
SVTISLHPLVIMNISEHWTRFPRQVYGALIGKQKGRNIEIMNSFELKTDVIGDETVINKDYYNKKEQQYKQVFSDLDFIGWYTTGDKIQRQIAAINECPIMLQLNPLSRSVDHLPLKLFES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of the MPN domain from the COP9 signalosome subunit CSN6
pubmed doi rcsb
molecule tags Unknown function
source organism Drosophila melanogaster
molecule keywords COP9 signalosome complex subunit 6
total genus 28
structure length 121
sequence length 134
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-03-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.140.10 Alpha Beta 3-Layer(aba) Sandwich Cytidine Deaminase; domain 2 Cytidine Deaminase, domain 2 4e0qA00
2G84A 1WWRA 1R5TA 3OCQA 2HVVA 1YSBA 1R5XA 1ZABA 2Z3HA 3IJFX 2G6VA 4LC5A 1Z3AA 4JXEA 3EX8A 3B8FA 2QLCA 1OI0A 2KKSA 1AF2A 3OJ6A 4HRQA 2FR6A 2D5NA 1CTTA 4MSJA 5M59B 4MSMA 2O3KA 4ZD5A 4MSQA 1RB7A 1WKQA 2P8RA 4O8YB 1TIYA 2NYTA 4ZD4A 4LD4A 3RZVA 2P87A 3ZEFB 4O8YA 4LCOA 2A8NA 2NX8A 5C2OA 2PW9A 4O8XB 2HVWA 4OCMB 4OWPA 4PQTA 4NQLA 3ZPGA 2KCQA 3DMOA 4O8XA 2W4LA 4OCMA 2B3JA 4K1RA 4BGDC 4MSDA 3SBGA 2O7PA 4LD2A 2OG4A 2FR5A 4F7OA 2ZNRA 3G8QA 4LCNA 4EG2A 2Z3GA 4LCPA 1JTKA 4G3MA 4WIFA 4P9EA 1VQ2A 5CW6A 4D10F 1WN6A 2O95A 2RPZA 4P9DA 5M52C 4ZFRA 2B3ZA 1UX0A 2D30A 4OWPB 1UAQA 1P6OA 4F3WA 2HXVA 3ZPCA 4OCNA 4WIGA 4OCLA 4I43B 5DCAJ 4ILGC 4MS7A 4P9CA 1WN5A 2ZNVA 4KITC 1UX1A 4QFTA 3RZUA 2Z3IA 1UWZA 4ZFTA 1CTUA 1MQ0A 4OCNB 5GAOA 1YSDA 4OCLB 3MPZA 3R2NA 1ALNA 2OBCA 4E0QA 2Z3JA 3DH1A 4HRWA 1OX7A 2O96A 3E1UA
chains in the Genus database with same CATH superfamily
2G84A 1WWRA 1R5TA 1P4RA 3OCQA 2HVVA 1YSBA 1R5XA 1ZABA 2Z3HA 3IJFX 2G6VA 4LC5A 4A1OA 1Z3AA 4JXEA 3EX8A 3B8FA 2QLCA 1OI0A 2KKSA 1AF2A 3OJ6A 4EHIA 4HRQA 2FR6A 2D5NA 4GGMX 1CTTA 1ZCZA 4MSJA 2IU3A 5M59B 4MSMA 2O3KA 4ZD5A 1VK9A 4MSQA 1RB7A 1WKQA 2P8RA 1PKXA 1THZA 4O8YB 1M9NA 1TIYA 2NYTA 4ZD4A 4LD4A 3VX8A 3RZVA 2P87A 3ZEFB 4O8YA 4LCOA 2A8NA 2NX8A 5C2OA 2PW9A 4O8XB 2HVWA 4OCMB 4OWPA 2IU0A 4PQTA 4NQLA 3ZPGA 2KCQA 3DMOA 4O8XA 2W4LA 4OCMA 2B3JA 4K1RA 4BGDC 2B1GA 4MSDA 3SBGA 2O7PA 4LD2A 2OG4A 1PL0A 2FR5A 1OZ0A 4F7OA 2ZNRA 3G8QA 4LCNA 4EG2A 2Z3GA 4LCPA 1JTKA 4G3MA 4WIFA 4P9EA 1VQ2A 5CW6A 4D10F 1WN6A 1G8MA 2O95A 2RPZA 4P9DA 5M52C 4ZFRA 2B3ZA 1UX0A 2D30A 4OWPB 3BH1A 1UAQA 1P6OA 4F3WA 2HXVA 3ZPCA 4OCNA 4WIGA 4OCLA 4I43B 5DCAJ 4ILGC 4MS7A 4P9CA 1WN5A 2ZNVA 4KITC 1UX1A 4QFTA 3RZUA 4J6EA 2Z3IA 1UWZA 3ZZMA 4ZFTA 1CTUA 1MQ0A 4OCNB 5GAOA 1YSDA 4OCLB 3MPZA 3R2NA 1ALNA 2B1IA 2OBCA 4E0QA 2Z3JA 3DH1A 4HRWA 1OX7A 2O96A 3E1UA
chains in the Genus database with same CATH topology
2G84A 1WWRA 1R5TA 3OCQA 2HVVA 1YSBA 1R5XA 1ZABA 2Z3HA 3IJFX 2G6VA 4LC5A 1Z3AA 4JXEA 3EX8A 3B8FA 2QLCA 1OI0A 2KKSA 1AF2A 3OJ6A 4HRQA 2FR6A 2D5NA 1CTTA 4MSJA 5M59B 4MSMA 2O3KA 4ZD5A 4MSQA 1RB7A 1WKQA 2P8RA 4O8YB 1TIYA 2NYTA 4ZD4A 4LD4A 3RZVA 2P87A 3ZEFB 4O8YA 4LCOA 2A8NA 2NX8A 5C2OA 2PW9A 4O8XB 2HVWA 4OCMB 4OWPA 4PQTA 4NQLA 3ZPGA 2KCQA 3DMOA 4O8XA 2W4LA 4OCMA 2B3JA 4K1RA 4BGDC 4MSDA 3SBGA 2O7PA 4LD2A 2OG4A 2FR5A 4F7OA 2ZNRA 3G8QA 4LCNA 4EG2A 2Z3GA 4LCPA 1JTKA 4G3MA 4WIFA 4P9EA 1VQ2A 5CW6A 4D10F 1WN6A 2O95A 2RPZA 4P9DA 5M52C 4ZFRA 2B3ZA 1UX0A 2D30A 4OWPB 1UAQA 1P6OA 4F3WA 2HXVA 3ZPCA 4OCNA 4WIGA 4OCLA 4I43B 5DCAJ 4ILGC 4MS7A 4P9CA 1WN5A 2ZNVA 4KITC 1UX1A 4QFTA 3RZUA 2Z3IA 1UWZA 4ZFTA 1CTUA 1MQ0A 4OCNB 5GAOA 1YSDA 4OCLB 3MPZA 3R2NA 1ALNA 2OBCA 4E0QA 2Z3JA 3DH1A 4HRWA 1OX7A 2O96A 3E1UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2G84 A;  1WWR A;  1R5T A;  3OCQ A;  2HVV A;  1YSB A;  1R5X A;  1ZAB A;  2Z3H A;  3IJF X;  2G6V A;  4LC5 A;  1Z3A A;  4JXE A;  3EX8 A;  3B8F A;  2QLC A;  1OI0 A;  2KKS A;  1AF2 A;  3OJ6 A;  4HRQ A;  2FR6 A;  2D5N A;  1CTT A;  4MSJ A;  5M59 B;  4MSM A;  2O3K A;  4ZD5 A;  4MSQ A;  1RB7 A;  1WKQ A;  2P8R A;  4O8Y B;  1TIY A;  2NYT A;  4ZD4 A;  4LD4 A;  3RZV A;  2P87 A;  3ZEF B;  4O8Y A;  4LCO A;  2A8N A;  2NX8 A;  5C2O A;  2PW9 A;  4O8X B;  2HVW A;  4OCM B;  4OWP A;  4PQT A;  4NQL A;  3ZPG A;  2KCQ A;  3DMO A;  4O8X A;  2W4L A;  4OCM A;  2B3J A;  4K1R A;  4BGD C;  4MSD A;  3SBG A;  2O7P A;  4LD2 A;  2OG4 A;  2FR5 A;  4F7O A;  2ZNR A;  3G8Q A;  4LCN A;  4EG2 A;  2Z3G A;  4LCP A;  1JTK A;  4G3M A;  4WIF A;  4P9E A;  1VQ2 A;  5CW6 A;  4D10 F;  1WN6 A;  2O95 A;  2RPZ A;  4P9D A;  5M52 C;  4ZFR A;  2B3Z A;  1UX0 A;  2D30 A;  4OWP B;  1UAQ A;  1P6O A;  4F3W A;  2HXV A;  3ZPC A;  4OCN A;  4WIG A;  4OCL A;  4I43 B;  5DCA J;  4ILG C;  4MS7 A;  4P9C A;  1WN5 A;  2ZNV A;  4KIT C;  1UX1 A;  4QFT A;  3RZU A;  2Z3I A;  1UWZ A;  4ZFT A;  1CTU A;  1MQ0 A;  4OCN B;  5GAO A;  1YSD A;  4OCL B;  3MPZ A;  3R2N A;  1ALN A;  2OBC A;  4E0Q A;  2Z3J A;  3DH1 A;  4HRW A;  1OX7 A;  2O96 A;  3E1U A; 
#chains in the Genus database with same CATH topology
 2G84 A;  1WWR A;  1R5T A;  1P4R A;  3OCQ A;  2HVV A;  1YSB A;  1R5X A;  1ZAB A;  2Z3H A;  3IJF X;  2G6V A;  4LC5 A;  4A1O A;  1Z3A A;  4JXE A;  3EX8 A;  3B8F A;  2QLC A;  1OI0 A;  2KKS A;  1AF2 A;  3OJ6 A;  4EHI A;  4HRQ A;  2FR6 A;  2D5N A;  4GGM X;  1CTT A;  1ZCZ A;  4MSJ A;  2IU3 A;  5M59 B;  4MSM A;  2O3K A;  4ZD5 A;  1VK9 A;  4MSQ A;  1RB7 A;  1WKQ A;  2P8R A;  1PKX A;  1THZ A;  4O8Y B;  1M9N A;  1TIY A;  2NYT A;  4ZD4 A;  4LD4 A;  3VX8 A;  3RZV A;  2P87 A;  3ZEF B;  4O8Y A;  4LCO A;  2A8N A;  2NX8 A;  5C2O A;  2PW9 A;  4O8X B;  2HVW A;  4OCM B;  4OWP A;  2IU0 A;  4PQT A;  4NQL A;  3ZPG A;  2KCQ A;  3DMO A;  4O8X A;  2W4L A;  4OCM A;  2B3J A;  4K1R A;  4BGD C;  2B1G A;  4MSD A;  3SBG A;  2O7P A;  4LD2 A;  2OG4 A;  1PL0 A;  2FR5 A;  1OZ0 A;  4F7O A;  2ZNR A;  3G8Q A;  4LCN A;  4EG2 A;  2Z3G A;  4LCP A;  1JTK A;  4G3M A;  4WIF A;  4P9E A;  1VQ2 A;  5CW6 A;  4D10 F;  1WN6 A;  1G8M A;  2O95 A;  2RPZ A;  4P9D A;  5M52 C;  4ZFR A;  2B3Z A;  1UX0 A;  2D30 A;  4OWP B;  3BH1 A;  1UAQ A;  1P6O A;  4F3W A;  2HXV A;  3ZPC A;  4OCN A;  4WIG A;  4OCL A;  4I43 B;  5DCA J;  4ILG C;  4MS7 A;  4P9C A;  1WN5 A;  2ZNV A;  4KIT C;  1UX1 A;  4QFT A;  3RZU A;  4J6E A;  2Z3I A;  1UWZ A;  3ZZM A;  4ZFT A;  1CTU A;  1MQ0 A;  4OCN B;  5GAO A;  1YSD A;  4OCL B;  3MPZ A;  3R2N A;  1ALN A;  2B1I A;  2OBC A;  4E0Q A;  2Z3J A;  3DH1 A;  4HRW A;  1OX7 A;  2O96 A;  3E1U A; 
#chains in the Genus database with same CATH homology
 2G84 A;  1WWR A;  1R5T A;  3OCQ A;  2HVV A;  1YSB A;  1R5X A;  1ZAB A;  2Z3H A;  3IJF X;  2G6V A;  4LC5 A;  1Z3A A;  4JXE A;  3EX8 A;  3B8F A;  2QLC A;  1OI0 A;  2KKS A;  1AF2 A;  3OJ6 A;  4HRQ A;  2FR6 A;  2D5N A;  1CTT A;  4MSJ A;  5M59 B;  4MSM A;  2O3K A;  4ZD5 A;  4MSQ A;  1RB7 A;  1WKQ A;  2P8R A;  4O8Y B;  1TIY A;  2NYT A;  4ZD4 A;  4LD4 A;  3RZV A;  2P87 A;  3ZEF B;  4O8Y A;  4LCO A;  2A8N A;  2NX8 A;  5C2O A;  2PW9 A;  4O8X B;  2HVW A;  4OCM B;  4OWP A;  4PQT A;  4NQL A;  3ZPG A;  2KCQ A;  3DMO A;  4O8X A;  2W4L A;  4OCM A;  2B3J A;  4K1R A;  4BGD C;  4MSD A;  3SBG A;  2O7P A;  4LD2 A;  2OG4 A;  2FR5 A;  4F7O A;  2ZNR A;  3G8Q A;  4LCN A;  4EG2 A;  2Z3G A;  4LCP A;  1JTK A;  4G3M A;  4WIF A;  4P9E A;  1VQ2 A;  5CW6 A;  4D10 F;  1WN6 A;  2O95 A;  2RPZ A;  4P9D A;  5M52 C;  4ZFR A;  2B3Z A;  1UX0 A;  2D30 A;  4OWP B;  1UAQ A;  1P6O A;  4F3W A;  2HXV A;  3ZPC A;  4OCN A;  4WIG A;  4OCL A;  4I43 B;  5DCA J;  4ILG C;  4MS7 A;  4P9C A;  1WN5 A;  2ZNV A;  4KIT C;  1UX1 A;  4QFT A;  3RZU A;  2Z3I A;  1UWZ A;  4ZFT A;  1CTU A;  1MQ0 A;  4OCN B;  5GAO A;  1YSD A;  4OCL B;  3MPZ A;  3R2N A;  1ALN A;  2OBC A;  4E0Q A;  2Z3J A;  3DH1 A;  4HRW A;  1OX7 A;  2O96 A;  3E1U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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