4F7OA

Crystal structure of csn5
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
256
structure length
235
Chain Sequence
AASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords COP9 signalosome complex subunit 5
total genus 59
structure length 235
sequence length 256
chains with identical sequence B
ec nomenclature ec 3.4.-.-:
pdb deposition date 2012-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01398 JAB JAB1/Mov34/MPN/PAD-1 ubiquitin protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.140.10 Alpha Beta 3-Layer(aba) Sandwich Cytidine Deaminase; domain 2 Cytidine Deaminase, domain 2 4f7oA00
2NYTA 2Z3GA 2RPZA 2OBCA 3RZUA 2W4LA 4WIFA 4LCOA 3RZVA 1Z3AA 3ZEFB 1WN6A 4O8YB 4O8XA 4ZD5A 4E0QA 4MSJA 3ZPGA 2P8RA 2P87A 4P9DA 4ZFRA 2B3ZA 4QFTA 2D30A 4OWPA 1R5XA 4P9CA 4EG2A 2Z3IA 3E1UA 1UWZA 1JTKA 1MQ0A 2OG4A 4KITC 2ZNVA 2O3KA 2O7PA 1WWRA 4O8XB 1UX0A 1CTTA 4BGDC 3R2NA 1OX7A 5M52C 3OCQA 4LCNA 2KCQA 1ALNA 3OJ6A 4OWPB 2G84A 5C2OA 4F7OA 4JXEA 3DMOA 3EX8A 4G3MA 1CTUA 1P6OA 1TIYA 4PQTA 2G6VA 2PW9A 2HVVA 4MSMA 2HVWA 1WKQA 4MS7A 4MSQA 4P9EA 1UX1A 5M59B 2D5NA 4ZD4A 2FR6A 1WN5A 2HXVA 4D10F 2ZNRA 3MPZA 4HRWA 4K1RA 1YSBA 4OCMA 4I43B 4ZFTA 1UAQA 2A8NA 4F3WA 3ZPCA 4OCLA 5GAOA 2NX8A 4OCNA 1AF2A 1ZABA 4LD2A 3B8FA 2O95A 2Z3HA 2KKSA 4OCMB 3SBGA 5DCAJ 3DH1A 1VQ2A 4ILGC 1R5TA 2FR5A 4LC5A 1OI0A 4MSDA 3G8QA 1RB7A 4OCLB 2B3JA 4O8YA 1YSDA 2O96A 4HRQA 2Z3JA 4LD4A 2QLCA 4NQLA 4OCNB 5CW6A 4WIGA 3IJFX 4LCPA
chains in the Genus database with same CATH superfamily
2NYTA 2Z3GA 2RPZA 2OBCA 3RZUA 2W4LA 4WIFA 4LCOA 3RZVA 1Z3AA 1G8MA 3ZEFB 1WN6A 4O8YB 4O8XA 4ZD5A 4E0QA 4MSJA 3ZPGA 2P8RA 2P87A 4P9DA 4ZFRA 2B3ZA 4QFTA 2D30A 2B1GA 4OWPA 1R5XA 4P9CA 4EG2A 2Z3IA 3E1UA 1THZA 1UWZA 1JTKA 1MQ0A 2OG4A 4KITC 2B1IA 2O3KA 2ZNVA 3VX8A 2O7PA 1WWRA 1VK9A 4O8XB 1UX0A 1CTTA 4BGDC 3R2NA 1OX7A 5M52C 3BH1A 3OCQA 4LCNA 2KCQA 1ALNA 3OJ6A 4OWPB 2G84A 1PKXA 5C2OA 4F7OA 4A1OA 4JXEA 3DMOA 3EX8A 4G3MA 1CTUA 1P6OA 1TIYA 4EHIA 4PQTA 2G6VA 2PW9A 1P4RA 2HVVA 4MSMA 3ZZMA 2HVWA 1WKQA 4MS7A 4MSQA 4P9EA 1UX1A 5M59B 2D5NA 4ZD4A 2FR6A 1OZ0A 1WN5A 2HXVA 4D10F 2ZNRA 3MPZA 4HRWA 4K1RA 1YSBA 4OCMA 4I43B 4ZFTA 1UAQA 2A8NA 4GGMX 4F3WA 3ZPCA 4OCLA 1ZCZA 5GAOA 1PL0A 2NX8A 4OCNA 4J6EA 1AF2A 1ZABA 4LD2A 3B8FA 2O95A 2Z3HA 2KKSA 4OCMB 3SBGA 2IU3A 5DCAJ 3DH1A 1VQ2A 4ILGC 1M9NA 1R5TA 2FR5A 4LC5A 1OI0A 4MSDA 3G8QA 1RB7A 4OCLB 2IU0A 2B3JA 4O8YA 1YSDA 2O96A 4HRQA 2Z3JA 4LD4A 2QLCA 4NQLA 4OCNB 5CW6A 4WIGA 3IJFX 4LCPA
chains in the Genus database with same CATH topology
2NYTA 2Z3GA 2RPZA 2OBCA 3RZUA 2W4LA 4WIFA 4LCOA 3RZVA 1Z3AA 3ZEFB 1WN6A 4O8YB 4O8XA 4ZD5A 4E0QA 4MSJA 3ZPGA 2P8RA 2P87A 4P9DA 4ZFRA 2B3ZA 4QFTA 2D30A 4OWPA 1R5XA 4P9CA 4EG2A 2Z3IA 3E1UA 1UWZA 1JTKA 1MQ0A 2OG4A 4KITC 2ZNVA 2O3KA 2O7PA 1WWRA 4O8XB 1UX0A 1CTTA 4BGDC 3R2NA 1OX7A 5M52C 3OCQA 4LCNA 2KCQA 1ALNA 3OJ6A 4OWPB 2G84A 5C2OA 4F7OA 4JXEA 3DMOA 3EX8A 4G3MA 1CTUA 1P6OA 1TIYA 4PQTA 2G6VA 2PW9A 2HVVA 4MSMA 2HVWA 1WKQA 4MS7A 4MSQA 4P9EA 1UX1A 5M59B 2D5NA 4ZD4A 2FR6A 1WN5A 2HXVA 4D10F 2ZNRA 3MPZA 4HRWA 4K1RA 1YSBA 4OCMA 4I43B 4ZFTA 1UAQA 2A8NA 4F3WA 3ZPCA 4OCLA 5GAOA 2NX8A 4OCNA 1AF2A 1ZABA 4LD2A 3B8FA 2O95A 2Z3HA 2KKSA 4OCMB 3SBGA 5DCAJ 3DH1A 1VQ2A 4ILGC 1R5TA 2FR5A 4LC5A 1OI0A 4MSDA 3G8QA 1RB7A 4OCLB 2B3JA 4O8YA 1YSDA 2O96A 4HRQA 2Z3JA 4LD4A 2QLCA 4NQLA 4OCNB 5CW6A 4WIGA 3IJFX 4LCPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NYT A;  2Z3G A;  2RPZ A;  2OBC A;  3RZU A;  2W4L A;  4WIF A;  4LCO A;  3RZV A;  1Z3A A;  3ZEF B;  1WN6 A;  4O8Y B;  4O8X A;  4ZD5 A;  4E0Q A;  4MSJ A;  3ZPG A;  2P8R A;  2P87 A;  4P9D A;  4ZFR A;  2B3Z A;  4QFT A;  2D30 A;  4OWP A;  1R5X A;  4P9C A;  4EG2 A;  2Z3I A;  3E1U A;  1UWZ A;  1JTK A;  1MQ0 A;  2OG4 A;  4KIT C;  2ZNV A;  2O3K A;  2O7P A;  1WWR A;  4O8X B;  1UX0 A;  1CTT A;  4BGD C;  3R2N A;  1OX7 A;  5M52 C;  3OCQ A;  4LCN A;  2KCQ A;  1ALN A;  3OJ6 A;  4OWP B;  2G84 A;  5C2O A;  4F7O A;  4JXE A;  3DMO A;  3EX8 A;  4G3M A;  1CTU A;  1P6O A;  1TIY A;  4PQT A;  2G6V A;  2PW9 A;  2HVV A;  4MSM A;  2HVW A;  1WKQ A;  4MS7 A;  4MSQ A;  4P9E A;  1UX1 A;  5M59 B;  2D5N A;  4ZD4 A;  2FR6 A;  1WN5 A;  2HXV A;  4D10 F;  2ZNR A;  3MPZ A;  4HRW A;  4K1R A;  1YSB A;  4OCM A;  4I43 B;  4ZFT A;  1UAQ A;  2A8N A;  4F3W A;  3ZPC A;  4OCL A;  5GAO A;  2NX8 A;  4OCN A;  1AF2 A;  1ZAB A;  4LD2 A;  3B8F A;  2O95 A;  2Z3H A;  2KKS A;  4OCM B;  3SBG A;  5DCA J;  3DH1 A;  1VQ2 A;  4ILG C;  1R5T A;  2FR5 A;  4LC5 A;  1OI0 A;  4MSD A;  3G8Q A;  1RB7 A;  4OCL B;  2B3J A;  4O8Y A;  1YSD A;  2O96 A;  4HRQ A;  2Z3J A;  4LD4 A;  2QLC A;  4NQL A;  4OCN B;  5CW6 A;  4WIG A;  3IJF X;  4LCP A; 
#chains in the Genus database with same CATH topology
 2NYT A;  2Z3G A;  2RPZ A;  2OBC A;  3RZU A;  2W4L A;  4WIF A;  4LCO A;  3RZV A;  1Z3A A;  1G8M A;  3ZEF B;  1WN6 A;  4O8Y B;  4O8X A;  4ZD5 A;  4E0Q A;  4MSJ A;  3ZPG A;  2P8R A;  2P87 A;  4P9D A;  4ZFR A;  2B3Z A;  4QFT A;  2D30 A;  2B1G A;  4OWP A;  1R5X A;  4P9C A;  4EG2 A;  2Z3I A;  3E1U A;  1THZ A;  1UWZ A;  1JTK A;  1MQ0 A;  2OG4 A;  4KIT C;  2B1I A;  2O3K A;  2ZNV A;  3VX8 A;  2O7P A;  1WWR A;  1VK9 A;  4O8X B;  1UX0 A;  1CTT A;  4BGD C;  3R2N A;  1OX7 A;  5M52 C;  3BH1 A;  3OCQ A;  4LCN A;  2KCQ A;  1ALN A;  3OJ6 A;  4OWP B;  2G84 A;  1PKX A;  5C2O A;  4F7O A;  4A1O A;  4JXE A;  3DMO A;  3EX8 A;  4G3M A;  1CTU A;  1P6O A;  1TIY A;  4EHI A;  4PQT A;  2G6V A;  2PW9 A;  1P4R A;  2HVV A;  4MSM A;  3ZZM A;  2HVW A;  1WKQ A;  4MS7 A;  4MSQ A;  4P9E A;  1UX1 A;  5M59 B;  2D5N A;  4ZD4 A;  2FR6 A;  1OZ0 A;  1WN5 A;  2HXV A;  4D10 F;  2ZNR A;  3MPZ A;  4HRW A;  4K1R A;  1YSB A;  4OCM A;  4I43 B;  4ZFT A;  1UAQ A;  2A8N A;  4GGM X;  4F3W A;  3ZPC A;  4OCL A;  1ZCZ A;  5GAO A;  1PL0 A;  2NX8 A;  4OCN A;  4J6E A;  1AF2 A;  1ZAB A;  4LD2 A;  3B8F A;  2O95 A;  2Z3H A;  2KKS A;  4OCM B;  3SBG A;  2IU3 A;  5DCA J;  3DH1 A;  1VQ2 A;  4ILG C;  1M9N A;  1R5T A;  2FR5 A;  4LC5 A;  1OI0 A;  4MSD A;  3G8Q A;  1RB7 A;  4OCL B;  2IU0 A;  2B3J A;  4O8Y A;  1YSD A;  2O96 A;  4HRQ A;  2Z3J A;  4LD4 A;  2QLC A;  4NQL A;  4OCN B;  5CW6 A;  4WIG A;  3IJF X;  4LCP A; 
#chains in the Genus database with same CATH homology
 2NYT A;  2Z3G A;  2RPZ A;  2OBC A;  3RZU A;  2W4L A;  4WIF A;  4LCO A;  3RZV A;  1Z3A A;  3ZEF B;  1WN6 A;  4O8Y B;  4O8X A;  4ZD5 A;  4E0Q A;  4MSJ A;  3ZPG A;  2P8R A;  2P87 A;  4P9D A;  4ZFR A;  2B3Z A;  4QFT A;  2D30 A;  4OWP A;  1R5X A;  4P9C A;  4EG2 A;  2Z3I A;  3E1U A;  1UWZ A;  1JTK A;  1MQ0 A;  2OG4 A;  4KIT C;  2ZNV A;  2O3K A;  2O7P A;  1WWR A;  4O8X B;  1UX0 A;  1CTT A;  4BGD C;  3R2N A;  1OX7 A;  5M52 C;  3OCQ A;  4LCN A;  2KCQ A;  1ALN A;  3OJ6 A;  4OWP B;  2G84 A;  5C2O A;  4F7O A;  4JXE A;  3DMO A;  3EX8 A;  4G3M A;  1CTU A;  1P6O A;  1TIY A;  4PQT A;  2G6V A;  2PW9 A;  2HVV A;  4MSM A;  2HVW A;  1WKQ A;  4MS7 A;  4MSQ A;  4P9E A;  1UX1 A;  5M59 B;  2D5N A;  4ZD4 A;  2FR6 A;  1WN5 A;  2HXV A;  4D10 F;  2ZNR A;  3MPZ A;  4HRW A;  4K1R A;  1YSB A;  4OCM A;  4I43 B;  4ZFT A;  1UAQ A;  2A8N A;  4F3W A;  3ZPC A;  4OCL A;  5GAO A;  2NX8 A;  4OCN A;  1AF2 A;  1ZAB A;  4LD2 A;  3B8F A;  2O95 A;  2Z3H A;  2KKS A;  4OCM B;  3SBG A;  5DCA J;  3DH1 A;  1VQ2 A;  4ILG C;  1R5T A;  2FR5 A;  4LC5 A;  1OI0 A;  4MSD A;  3G8Q A;  1RB7 A;  4OCL B;  2B3J A;  4O8Y A;  1YSD A;  2O96 A;  4HRQ A;  2Z3J A;  4LD4 A;  2QLC A;  4NQL A;  4OCN B;  5CW6 A;  4WIG A;  3IJF X;  4LCP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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