4F7OA

Crystal structure of csn5
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
256
structure length
235
Chain Sequence
AASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords COP9 signalosome complex subunit 5
total genus 59
structure length 235
sequence length 256
chains with identical sequence B
ec nomenclature ec 3.4.-.-:
pdb deposition date 2012-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01398 JAB JAB1/Mov34/MPN/PAD-1 ubiquitin protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.140.10 Alpha Beta 3-Layer(aba) Sandwich Cytidine Deaminase; domain 2 Cytidine Deaminase, domain 2 4f7oA00
4HRQA 3DMOA 3E1UA 1UX0A 2FR5A 2KCQA 2B3JA 4ZD5A 1MQ0A 4HRWA 1ALNA 1ZABA 4LD2A 1AF2A 4P9CA 4F7OA 5GAOA 2P87A 4OWPB 4KITC 4ZFRA 2Z3HA 3G8QA 1CTUA 4O8YB 3R2NA 2G6VA 1Z3AA 5M59B 3EX8A 2W4LA 3ZPCA 3OCQA 2HXVA 2D30A 4K1RA 4P9EA 2Z3IA 4OCNB 2KKSA 2D5NA 1UWZA 1WN5A 2QLCA 2RPZA 3B8FA 1R5TA 5CW6A 2P8RA 4MSMA 5DCAJ 2HVWA 2OG4A 2OBCA 1WWRA 1RB7A 4WIGA 4EG2A 1CTTA 2FR6A 4OCLB 1OI0A 2O7PA 5M52C 4MSDA 4E0QA 1TIYA 2PW9A 4O8XB 4OWPA 3OJ6A 4JXEA 4PQTA 4OCMB 1WN6A 4O8YA 2O3KA 1UX1A 3ZPGA 2NX8A 3MPZA 2G84A 1VQ2A 2ZNVA 1P6OA 2B3ZA 4ZFTA 4MSJA 4OCNA 4I43B 3ZEFB 4NQLA 4ZD4A 3SBGA 4LCOA 4OCMA 2O96A 4F3WA 4MSQA 4MS7A 1R5XA 4LD4A 4LCPA 4D10F 2Z3JA 2Z3GA 2A8NA 2HVVA 2O95A 4WIFA 4BGDC 4QFTA 4ILGC 4LCNA 1YSDA 1OX7A 4OCLA 2NYTA 4P9DA 5C2OA 1UAQA 2ZNRA 3RZVA 3DH1A 4G3MA 4LC5A 3IJFX 4O8XA 1WKQA 3RZUA 1YSBA 1JTKA
chains in the Genus database with same CATH superfamily
4HRQA 3DMOA 3E1UA 1UX0A 2FR5A 2KCQA 2B3JA 4ZD5A 1MQ0A 4HRWA 1PKXA 1ALNA 1ZABA 4LD2A 1AF2A 4P9CA 4F7OA 5GAOA 2P87A 4OWPB 4KITC 1THZA 4ZFRA 4GGMX 2Z3HA 3G8QA 1CTUA 4O8YB 3R2NA 2G6VA 1Z3AA 5M59B 3EX8A 4EHIA 2W4LA 3ZPCA 2HXVA 3OCQA 2D30A 4K1RA 4P9EA 2Z3IA 4A1OA 4OCNB 2KKSA 1G8MA 2D5NA 1UWZA 1WN5A 1OZ0A 2QLCA 2RPZA 3B8FA 1R5TA 5CW6A 3BH1A 2P8RA 4MSMA 5DCAJ 2HVWA 2OG4A 2OBCA 4J6EA 1WWRA 1RB7A 4WIGA 4EG2A 1CTTA 2FR6A 4OCLB 1ZCZA 1OI0A 2O7PA 5M52C 2IU3A 4MSDA 4E0QA 3VX8A 1TIYA 2PW9A 1VK9A 4O8XB 4OWPA 3OJ6A 4JXEA 4PQTA 4OCMB 2IU0A 1WN6A 1P4RA 4O8YA 2B1GA 2O3KA 1UX1A 3ZPGA 2NX8A 3MPZA 2G84A 1VQ2A 2ZNVA 1M9NA 1P6OA 2B3ZA 2B1IA 4ZFTA 4MSJA 4OCNA 4I43B 3ZEFB 1PL0A 4NQLA 4ZD4A 3SBGA 4LCOA 4OCMA 2O96A 4F3WA 4MSQA 4MS7A 1R5XA 4LD4A 4LCPA 4D10F 3ZZMA 2Z3JA 2Z3GA 2A8NA 2HVVA 2O95A 4WIFA 4BGDC 4QFTA 4ILGC 4LCNA 1YSDA 1OX7A 4OCLA 2NYTA 4P9DA 5C2OA 1UAQA 2ZNRA 3RZVA 3DH1A 4G3MA 4LC5A 3IJFX 4O8XA 1WKQA 3RZUA 1YSBA 1JTKA
chains in the Genus database with same CATH topology
4HRQA 3DMOA 3E1UA 1UX0A 2FR5A 2KCQA 2B3JA 4ZD5A 1MQ0A 4HRWA 1ALNA 1ZABA 4LD2A 1AF2A 4P9CA 4F7OA 5GAOA 2P87A 4OWPB 4KITC 4ZFRA 2Z3HA 3G8QA 1CTUA 4O8YB 3R2NA 2G6VA 1Z3AA 5M59B 3EX8A 2W4LA 3ZPCA 3OCQA 2HXVA 2D30A 4K1RA 4P9EA 2Z3IA 4OCNB 2KKSA 2D5NA 1UWZA 1WN5A 2QLCA 2RPZA 3B8FA 1R5TA 5CW6A 2P8RA 4MSMA 5DCAJ 2HVWA 2OG4A 2OBCA 1WWRA 1RB7A 4WIGA 4EG2A 1CTTA 2FR6A 4OCLB 1OI0A 2O7PA 5M52C 4MSDA 4E0QA 1TIYA 2PW9A 4O8XB 4OWPA 3OJ6A 4JXEA 4PQTA 4OCMB 1WN6A 4O8YA 2O3KA 1UX1A 3ZPGA 2NX8A 3MPZA 2G84A 1VQ2A 2ZNVA 1P6OA 2B3ZA 4ZFTA 4MSJA 4OCNA 4I43B 3ZEFB 4NQLA 4ZD4A 3SBGA 4LCOA 4OCMA 2O96A 4F3WA 4MSQA 4MS7A 1R5XA 4LD4A 4LCPA 4D10F 2Z3JA 2Z3GA 2A8NA 2HVVA 2O95A 4WIFA 4BGDC 4QFTA 4ILGC 4LCNA 1YSDA 1OX7A 4OCLA 2NYTA 4P9DA 5C2OA 1UAQA 2ZNRA 3RZVA 3DH1A 4G3MA 4LC5A 3IJFX 4O8XA 1WKQA 3RZUA 1YSBA 1JTKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HRQ A;  3DMO A;  3E1U A;  1UX0 A;  2FR5 A;  2KCQ A;  2B3J A;  4ZD5 A;  1MQ0 A;  4HRW A;  1ALN A;  1ZAB A;  4LD2 A;  1AF2 A;  4P9C A;  4F7O A;  5GAO A;  2P87 A;  4OWP B;  4KIT C;  4ZFR A;  2Z3H A;  3G8Q A;  1CTU A;  4O8Y B;  3R2N A;  2G6V A;  1Z3A A;  5M59 B;  3EX8 A;  2W4L A;  3ZPC A;  3OCQ A;  2HXV A;  2D30 A;  4K1R A;  4P9E A;  2Z3I A;  4OCN B;  2KKS A;  2D5N A;  1UWZ A;  1WN5 A;  2QLC A;  2RPZ A;  3B8F A;  1R5T A;  5CW6 A;  2P8R A;  4MSM A;  5DCA J;  2HVW A;  2OG4 A;  2OBC A;  1WWR A;  1RB7 A;  4WIG A;  4EG2 A;  1CTT A;  2FR6 A;  4OCL B;  1OI0 A;  2O7P A;  5M52 C;  4MSD A;  4E0Q A;  1TIY A;  2PW9 A;  4O8X B;  4OWP A;  3OJ6 A;  4JXE A;  4PQT A;  4OCM B;  1WN6 A;  4O8Y A;  2O3K A;  1UX1 A;  3ZPG A;  2NX8 A;  3MPZ A;  2G84 A;  1VQ2 A;  2ZNV A;  1P6O A;  2B3Z A;  4ZFT A;  4MSJ A;  4OCN A;  4I43 B;  3ZEF B;  4NQL A;  4ZD4 A;  3SBG A;  4LCO A;  4OCM A;  2O96 A;  4F3W A;  4MSQ A;  4MS7 A;  1R5X A;  4LD4 A;  4LCP A;  4D10 F;  2Z3J A;  2Z3G A;  2A8N A;  2HVV A;  2O95 A;  4WIF A;  4BGD C;  4QFT A;  4ILG C;  4LCN A;  1YSD A;  1OX7 A;  4OCL A;  2NYT A;  4P9D A;  5C2O A;  1UAQ A;  2ZNR A;  3RZV A;  3DH1 A;  4G3M A;  4LC5 A;  3IJF X;  4O8X A;  1WKQ A;  3RZU A;  1YSB A;  1JTK A; 
#chains in the Genus database with same CATH topology
 4HRQ A;  3DMO A;  3E1U A;  1UX0 A;  2FR5 A;  2KCQ A;  2B3J A;  4ZD5 A;  1MQ0 A;  4HRW A;  1PKX A;  1ALN A;  1ZAB A;  4LD2 A;  1AF2 A;  4P9C A;  4F7O A;  5GAO A;  2P87 A;  4OWP B;  4KIT C;  1THZ A;  4ZFR A;  4GGM X;  2Z3H A;  3G8Q A;  1CTU A;  4O8Y B;  3R2N A;  2G6V A;  1Z3A A;  5M59 B;  3EX8 A;  4EHI A;  2W4L A;  3ZPC A;  2HXV A;  3OCQ A;  2D30 A;  4K1R A;  4P9E A;  2Z3I A;  4A1O A;  4OCN B;  2KKS A;  1G8M A;  2D5N A;  1UWZ A;  1WN5 A;  1OZ0 A;  2QLC A;  2RPZ A;  3B8F A;  1R5T A;  5CW6 A;  3BH1 A;  2P8R A;  4MSM A;  5DCA J;  2HVW A;  2OG4 A;  2OBC A;  4J6E A;  1WWR A;  1RB7 A;  4WIG A;  4EG2 A;  1CTT A;  2FR6 A;  4OCL B;  1ZCZ A;  1OI0 A;  2O7P A;  5M52 C;  2IU3 A;  4MSD A;  4E0Q A;  3VX8 A;  1TIY A;  2PW9 A;  1VK9 A;  4O8X B;  4OWP A;  3OJ6 A;  4JXE A;  4PQT A;  4OCM B;  2IU0 A;  1WN6 A;  1P4R A;  4O8Y A;  2B1G A;  2O3K A;  1UX1 A;  3ZPG A;  2NX8 A;  3MPZ A;  2G84 A;  1VQ2 A;  2ZNV A;  1M9N A;  1P6O A;  2B3Z A;  2B1I A;  4ZFT A;  4MSJ A;  4OCN A;  4I43 B;  3ZEF B;  1PL0 A;  4NQL A;  4ZD4 A;  3SBG A;  4LCO A;  4OCM A;  2O96 A;  4F3W A;  4MSQ A;  4MS7 A;  1R5X A;  4LD4 A;  4LCP A;  4D10 F;  3ZZM A;  2Z3J A;  2Z3G A;  2A8N A;  2HVV A;  2O95 A;  4WIF A;  4BGD C;  4QFT A;  4ILG C;  4LCN A;  1YSD A;  1OX7 A;  4OCL A;  2NYT A;  4P9D A;  5C2O A;  1UAQ A;  2ZNR A;  3RZV A;  3DH1 A;  4G3M A;  4LC5 A;  3IJF X;  4O8X A;  1WKQ A;  3RZU A;  1YSB A;  1JTK A; 
#chains in the Genus database with same CATH homology
 4HRQ A;  3DMO A;  3E1U A;  1UX0 A;  2FR5 A;  2KCQ A;  2B3J A;  4ZD5 A;  1MQ0 A;  4HRW A;  1ALN A;  1ZAB A;  4LD2 A;  1AF2 A;  4P9C A;  4F7O A;  5GAO A;  2P87 A;  4OWP B;  4KIT C;  4ZFR A;  2Z3H A;  3G8Q A;  1CTU A;  4O8Y B;  3R2N A;  2G6V A;  1Z3A A;  5M59 B;  3EX8 A;  2W4L A;  3ZPC A;  3OCQ A;  2HXV A;  2D30 A;  4K1R A;  4P9E A;  2Z3I A;  4OCN B;  2KKS A;  2D5N A;  1UWZ A;  1WN5 A;  2QLC A;  2RPZ A;  3B8F A;  1R5T A;  5CW6 A;  2P8R A;  4MSM A;  5DCA J;  2HVW A;  2OG4 A;  2OBC A;  1WWR A;  1RB7 A;  4WIG A;  4EG2 A;  1CTT A;  2FR6 A;  4OCL B;  1OI0 A;  2O7P A;  5M52 C;  4MSD A;  4E0Q A;  1TIY A;  2PW9 A;  4O8X B;  4OWP A;  3OJ6 A;  4JXE A;  4PQT A;  4OCM B;  1WN6 A;  4O8Y A;  2O3K A;  1UX1 A;  3ZPG A;  2NX8 A;  3MPZ A;  2G84 A;  1VQ2 A;  2ZNV A;  1P6O A;  2B3Z A;  4ZFT A;  4MSJ A;  4OCN A;  4I43 B;  3ZEF B;  4NQL A;  4ZD4 A;  3SBG A;  4LCO A;  4OCM A;  2O96 A;  4F3W A;  4MSQ A;  4MS7 A;  1R5X A;  4LD4 A;  4LCP A;  4D10 F;  2Z3J A;  2Z3G A;  2A8N A;  2HVV A;  2O95 A;  4WIF A;  4BGD C;  4QFT A;  4ILG C;  4LCN A;  1YSD A;  1OX7 A;  4OCL A;  2NYT A;  4P9D A;  5C2O A;  1UAQ A;  2ZNR A;  3RZV A;  3DH1 A;  4G3M A;  4LC5 A;  3IJF X;  4O8X A;  1WKQ A;  3RZU A;  1YSB A;  1JTK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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