4O8Y | Genus

Total Genus 48

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	48
sequence length	180
structure length	174
Chain Sequence	SLQHEKVTIAPLVLLSALDHYERTQTKENKRCVGVILGDANSSTIRVTNSFALPFEEDEKNSDVWFLDHNYIENMNEMCKKINAKEKLIGWYHSGPKLRASDLKINELFKKYTQNNPLLLIVDVKQQGVGLPTDAYVAIEQVTEKTFLHLPCTIEAEEAEEIGVEHLLRDVLEV

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Saccharomyces cerevisiae
publication title	Structure of the Rpn11-Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradation. pubmed doi rcsb
molecule keywords	26S proteasome regulatory subunit RPN8
total genus	48
structure length	174
sequence length	180
ec nomenclature
pdb deposition date	2013-12-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01398	JAB	JAB1/Mov34/MPN/PAD-1 ubiquitin protease

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.140.10	Alpha Beta	3-Layer(aba) Sandwich	Cytidine Deaminase; domain 2	Cytidine Deaminase, domain 2	4o8yA00

3RZVA 2ZNRA 3SBGA 3ZPGA 1WKQA 1P6OA 2G6VA 4ZD5A 4LD4A 5CW6A 5C2OA 2O95A 4OCLA 1YSBA 4OWPA 4G3MA 4MS7A 2FR6A 4P9CA 3MPZA 4KITC 2RPZA 3OJ6A 4P9DA 4K1RA 4D10F 2HXVA 4LCOA 4O8YB 4HRQA 1JTKA 5M59B 4E0QA 1OI0A 4NQLA 2Z3HA 2ZNVA 4MSQA 4LC5A 4ZFRA 4O8XA 4HRWA 4I43B 3ZPCA 1UWZA 4ZD4A 3R2NA 1CTUA 2G84A 4OCLB 2HVWA 3E1UA 3IJFX 2O3KA 4OCMA 4F7OA 1AF2A 2P87A 4MSMA 2PW9A 2Z3IA 2P8RA 1UX0A 4OCNA 3OCQA 2B3ZA 2HVVA 4LCPA 2B3JA 1YSDA 5GAOA 3EX8A 4WIGA 2Z3JA 4ILGC 2D5NA 5DCAJ 1Z3AA 4QFTA 3ZEFB 4F3WA 3RZUA 1RB7A 1WN5A 2NYTA 2W4LA 1ZABA 1WWRA 4MSDA 4OWPB 1R5XA 4ZFTA 4EG2A 1CTTA 3DMOA 2QLCA 4OCMB 2OG4A 4JXEA 1UAQA 1VQ2A 2A8NA 2FR5A 1UX1A 3G8QA 4OCNB 4PQTA 4WIFA 1MQ0A 4LD2A 2KCQA 2O96A 4BGDC 5M52C 3B8FA 4O8XB 1TIYA 4P9EA 1R5TA 2OBCA 2D30A 2O7PA 4O8YA 4LCNA 3DH1A 1ALNA 1OX7A 2Z3GA 2NX8A 4MSJA 1WN6A 2KKSA
chains in the Genus database with same CATH superfamily

3RZVA 2ZNRA 3SBGA 1M9NA 3ZPGA 1WKQA 1P6OA 1OZ0A 2G6VA 4ZD5A 4LD4A 5CW6A 5C2OA 2O95A 4OCLA 1YSBA 4OWPA 4G3MA 4MS7A 2FR6A 4P9CA 3BH1A 3MPZA 4KITC 2RPZA 3OJ6A 4P9DA 4K1RA 4D10F 2HXVA 4LCOA 4O8YB 2B1GA 4HRQA 1JTKA 5M59B 4E0QA 1OI0A 4NQLA 2Z3HA 2ZNVA 4MSQA 4LC5A 4ZFRA 4O8XA 4HRWA 4I43B 3ZPCA 1UWZA 4ZD4A 3R2NA 1THZA 1CTUA 1P4RA 2G84A 2IU3A 4OCLB 2HVWA 3E1UA 3IJFX 1PKXA 2O3KA 4OCMA 4F7OA 1AF2A 2P87A 4J6EA 1VK9A 4MSMA 4GGMX 2PW9A 2Z3IA 2P8RA 1UX0A 2IU0A 4OCNA 3OCQA 2B3ZA 2HVVA 4LCPA 2B3JA 1YSDA 5GAOA 3EX8A 4WIGA 1ZCZA 2Z3JA 4EHIA 4ILGC 2D5NA 5DCAJ 1Z3AA 1PL0A 4QFTA 3ZZMA 3ZEFB 4F3WA 3RZUA 1RB7A 1WN5A 2NYTA 2W4LA 1ZABA 1WWRA 2B1IA 4MSDA 4OWPB 1R5XA 4A1OA 4ZFTA 4EG2A 1CTTA 3DMOA 2QLCA 4OCMB 2OG4A 4JXEA 1UAQA 1VQ2A 2A8NA 1G8MA 2FR5A 1UX1A 3G8QA 4OCNB 4PQTA 4WIFA 1MQ0A 4LD2A 2KCQA 2O96A 4BGDC 5M52C 3B8FA 4O8XB 1TIYA 3VX8A 4P9EA 1R5TA 2OBCA 2D30A 2O7PA 4O8YA 4LCNA 3DH1A 1ALNA 1OX7A 2Z3GA 2NX8A 4MSJA 1WN6A 2KKSA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3RZV A;  2ZNR A;  3SBG A;  3ZPG A;  1WKQ A;  1P6O A;  2G6V A;  4ZD5 A;  4LD4 A;  5CW6 A;  5C2O A;  2O95 A;  4OCL A;  1YSB A;  4OWP A;  4G3M A;  4MS7 A;  2FR6 A;  4P9C A;  3MPZ A;  4KIT C;  2RPZ A;  3OJ6 A;  4P9D A;  4K1R A;  4D10 F;  2HXV A;  4LCO A;  4O8Y B;  4HRQ A;  1JTK A;  5M59 B;  4E0Q A;  1OI0 A;  4NQL A;  2Z3H A;  2ZNV A;  4MSQ A;  4LC5 A;  4ZFR A;  4O8X A;  4HRW A;  4I43 B;  3ZPC A;  1UWZ A;  4ZD4 A;  3R2N A;  1CTU A;  2G84 A;  4OCL B;  2HVW A;  3E1U A;  3IJF X;  2O3K A;  4OCM A;  4F7O A;  1AF2 A;  2P87 A;  4MSM A;  2PW9 A;  2Z3I A;  2P8R A;  1UX0 A;  4OCN A;  3OCQ A;  2B3Z A;  2HVV A;  4LCP A;  2B3J A;  1YSD A;  5GAO A;  3EX8 A;  4WIG A;  2Z3J A;  4ILG C;  2D5N A;  5DCA J;  1Z3A A;  4QFT A;  3ZEF B;  4F3W A;  3RZU A;  1RB7 A;  1WN5 A;  2NYT A;  2W4L A;  1ZAB A;  1WWR A;  4MSD A;  4OWP B;  1R5X A;  4ZFT A;  4EG2 A;  1CTT A;  3DMO A;  2QLC A;  4OCM B;  2OG4 A;  4JXE A;  1UAQ A;  1VQ2 A;  2A8N A;  2FR5 A;  1UX1 A;  3G8Q A;  4OCN B;  4PQT A;  4WIF A;  1MQ0 A;  4LD2 A;  2KCQ A;  2O96 A;  4BGD C;  5M52 C;  3B8F A;  4O8X B;  1TIY A;  4P9E A;  1R5T A;  2OBC A;  2D30 A;  2O7P A;  4O8Y A;  4LCN A;  3DH1 A;  1ALN A;  1OX7 A;  2Z3G A;  2NX8 A;  4MSJ A;  1WN6 A;  2KKS A; 
#chains in the Genus database with same CATH topology
 3RZV A;  2ZNR A;  3SBG A;  1M9N A;  3ZPG A;  1WKQ A;  1P6O A;  1OZ0 A;  2G6V A;  4ZD5 A;  4LD4 A;  5CW6 A;  5C2O A;  2O95 A;  4OCL A;  1YSB A;  4OWP A;  4G3M A;  4MS7 A;  2FR6 A;  4P9C A;  3BH1 A;  3MPZ A;  4KIT C;  2RPZ A;  3OJ6 A;  4P9D A;  4K1R A;  4D10 F;  2HXV A;  4LCO A;  4O8Y B;  2B1G A;  4HRQ A;  1JTK A;  5M59 B;  4E0Q A;  1OI0 A;  4NQL A;  2Z3H A;  2ZNV A;  4MSQ A;  4LC5 A;  4ZFR A;  4O8X A;  4HRW A;  4I43 B;  3ZPC A;  1UWZ A;  4ZD4 A;  3R2N A;  1THZ A;  1CTU A;  1P4R A;  2G84 A;  2IU3 A;  4OCL B;  2HVW A;  3E1U A;  3IJF X;  1PKX A;  2O3K A;  4OCM A;  4F7O A;  1AF2 A;  2P87 A;  4J6E A;  1VK9 A;  4MSM A;  4GGM X;  2PW9 A;  2Z3I A;  2P8R A;  1UX0 A;  2IU0 A;  4OCN A;  3OCQ A;  2B3Z A;  2HVV A;  4LCP A;  2B3J A;  1YSD A;  5GAO A;  3EX8 A;  4WIG A;  1ZCZ A;  2Z3J A;  4EHI A;  4ILG C;  2D5N A;  5DCA J;  1Z3A A;  1PL0 A;  4QFT A;  3ZZM A;  3ZEF B;  4F3W A;  3RZU A;  1RB7 A;  1WN5 A;  2NYT A;  2W4L A;  1ZAB A;  1WWR A;  2B1I A;  4MSD A;  4OWP B;  1R5X A;  4A1O A;  4ZFT A;  4EG2 A;  1CTT A;  3DMO A;  2QLC A;  4OCM B;  2OG4 A;  4JXE A;  1UAQ A;  1VQ2 A;  2A8N A;  1G8M A;  2FR5 A;  1UX1 A;  3G8Q A;  4OCN B;  4PQT A;  4WIF A;  1MQ0 A;  4LD2 A;  2KCQ A;  2O96 A;  4BGD C;  5M52 C;  3B8F A;  4O8X B;  1TIY A;  3VX8 A;  4P9E A;  1R5T A;  2OBC A;  2D30 A;  2O7P A;  4O8Y A;  4LCN A;  3DH1 A;  1ALN A;  1OX7 A;  2Z3G A;  2NX8 A;  4MSJ A;  1WN6 A;  2KKS A; 
#chains in the Genus database with same CATH homology
 3RZV A;  2ZNR A;  3SBG A;  3ZPG A;  1WKQ A;  1P6O A;  2G6V A;  4ZD5 A;  4LD4 A;  5CW6 A;  5C2O A;  2O95 A;  4OCL A;  1YSB A;  4OWP A;  4G3M A;  4MS7 A;  2FR6 A;  4P9C A;  3MPZ A;  4KIT C;  2RPZ A;  3OJ6 A;  4P9D A;  4K1R A;  4D10 F;  2HXV A;  4LCO A;  4O8Y B;  4HRQ A;  1JTK A;  5M59 B;  4E0Q A;  1OI0 A;  4NQL A;  2Z3H A;  2ZNV A;  4MSQ A;  4LC5 A;  4ZFR A;  4O8X A;  4HRW A;  4I43 B;  3ZPC A;  1UWZ A;  4ZD4 A;  3R2N A;  1CTU A;  2G84 A;  4OCL B;  2HVW A;  3E1U A;  3IJF X;  2O3K A;  4OCM A;  4F7O A;  1AF2 A;  2P87 A;  4MSM A;  2PW9 A;  2Z3I A;  2P8R A;  1UX0 A;  4OCN A;  3OCQ A;  2B3Z A;  2HVV A;  4LCP A;  2B3J A;  1YSD A;  5GAO A;  3EX8 A;  4WIG A;  2Z3J A;  4ILG C;  2D5N A;  5DCA J;  1Z3A A;  4QFT A;  3ZEF B;  4F3W A;  3RZU A;  1RB7 A;  1WN5 A;  2NYT A;  2W4L A;  1ZAB A;  1WWR A;  4MSD A;  4OWP B;  1R5X A;  4ZFT A;  4EG2 A;  1CTT A;  3DMO A;  2QLC A;  4OCM B;  2OG4 A;  4JXE A;  1UAQ A;  1VQ2 A;  2A8N A;  2FR5 A;  1UX1 A;  3G8Q A;  4OCN B;  4PQT A;  4WIF A;  1MQ0 A;  4LD2 A;  2KCQ A;  2O96 A;  4BGD C;  5M52 C;  3B8F A;  4O8X B;  1TIY A;  4P9E A;  1R5T A;  2OBC A;  2D30 A;  2O7P A;  4O8Y A;  4LCN A;  3DH1 A;  1ALN A;  1OX7 A;  2Z3G A;  2NX8 A;  4MSJ A;  1WN6 A;  2KKS A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4O8YA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations