5DCAJ

Crystal structure of yeast full length brr2 in complex with prp8 jab1 domain
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
251
structure length
251
Chain Sequence
SKNEWRKSAIANTLLYLRLKNIYVSADDFVEEQNVYVLPKNLLKKFIEISDVKIQVAAFIYGMSAKDHPKVKEIKTVVLVPQLGHVGSVQISNIPDIGDLPDTEGLELLGWIHTQTEELKFMAASEVATHSKLFADKKRDCIDISIFSTPGSVSLSAYNLTDEGYQWGEENKDIMNVLSEGFEPTFSTHAQLLLSDRITGNFIIPSGNVWNYTFMGTAFNQEGDYNFKYGIPLEFYNEMHRPVHFLQFSEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation.
pubmed doi rcsb
molecule tags Hydrolase
source organism Saccharomyces cerevisiae (strain atcc 204508 / s288c)
molecule keywords Pre-mRNA-splicing helicase BRR2
total genus 72
structure length 251
sequence length 251
ec nomenclature
pdb deposition date 2015-08-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.140.10 Alpha Beta 3-Layer(aba) Sandwich Cytidine Deaminase; domain 2 Cytidine Deaminase, domain 2 5dcaJ01
4BGDC 1JTKA 4LD4A 1R5XA 1Z3AA 4OCMA 4NQLA 3DH1A 2O96A 4O8YA 2Z3IA 2RPZA 2KCQA 4OWPA 4MSQA 1MQ0A 1CTUA 1TIYA 2O3KA 4MSJA 2D30A 2A8NA 1WN6A 2OG4A 1WKQA 4P9DA 4OCLB 2P8RA 4LCNA 1ALNA 3ZEFB 1UX1A 2KKSA 4ZD5A 2NX8A 4MSDA 3DMOA 2Z3HA 1CTTA 2NYTA 2HXVA 4LD2A 4D10F 4ZFTA 5M59B 2D5NA 5M52C 2HVWA 3R2NA 3IJFX 4LCPA 2Z3GA 3E1UA 4JXEA 4OCNB 4LC5A 3MPZA 1OI0A 4OCMB 4I43B 1VQ2A 4O8YB 2G6VA 4O8XA 2ZNRA 3OCQA 3RZUA 4ZD4A 2PW9A 1WN5A 4HRQA 4F3WA 1OX7A 5DCAJ 2FR5A 5C2OA 3OJ6A 4WIFA 2O95A 3EX8A 3ZPCA 4QFTA 2P87A 4F7OA 4HRWA 4G3MA 1P6OA 4P9EA 4PQTA 4E0QA 2OBCA 4WIGA 1YSBA 2W4LA 1UAQA 4OWPB 4MSMA 1UX0A 4KITC 2B3ZA 4OCLA 2Z3JA 1ZABA 3RZVA 1RB7A 1R5TA 4MS7A 1YSDA 5CW6A 1UWZA 2QLCA 4LCOA 3G8QA 1AF2A 2HVVA 2FR6A 3B8FA 4P9CA 2O7PA 4O8XB 2B3JA 3SBGA 1WWRA 2G84A 4EG2A 5GAOA 4ILGC 4ZFRA 4K1RA 4OCNA 3ZPGA 2ZNVA
chains in the Genus database with same CATH superfamily
4BGDC 1JTKA 4LD4A 1R5XA 1Z3AA 4OCMA 4NQLA 3DH1A 2B1IA 2O96A 4O8YA 1PL0A 2Z3IA 2RPZA 2KCQA 4OWPA 4MSQA 1MQ0A 1CTUA 1TIYA 2O3KA 4MSJA 2D30A 2A8NA 1WN6A 2OG4A 1WKQA 4P9DA 4OCLB 2P8RA 4LCNA 1ALNA 3ZEFB 1UX1A 4A1OA 2KKSA 1OZ0A 4ZD5A 2NX8A 4MSDA 3DMOA 1G8MA 3VX8A 2Z3HA 1CTTA 2NYTA 2HXVA 4LD2A 4D10F 4ZFTA 5M59B 2D5NA 5M52C 2HVWA 3R2NA 3IJFX 4LCPA 2Z3GA 3E1UA 4JXEA 4OCNB 3BH1A 4LC5A 3MPZA 1OI0A 4OCMB 4I43B 1VQ2A 4O8YB 2G6VA 4O8XA 2ZNRA 1P4RA 1ZCZA 3OCQA 3RZUA 4ZD4A 2PW9A 1PKXA 1WN5A 4HRQA 4F3WA 2IU0A 1OX7A 5DCAJ 2FR5A 4EHIA 5C2OA 3OJ6A 4WIFA 2O95A 3EX8A 3ZPCA 4QFTA 2P87A 4F7OA 4HRWA 4G3MA 4J6EA 1P6OA 2IU3A 4P9EA 4PQTA 4E0QA 2OBCA 4WIGA 1YSBA 2W4LA 1UAQA 4OWPB 4MSMA 1UX0A 4KITC 2B3ZA 4OCLA 2Z3JA 1ZABA 3RZVA 1RB7A 1R5TA 4MS7A 1YSDA 5CW6A 1UWZA 2QLCA 4LCOA 3G8QA 1AF2A 2HVVA 2FR6A 3B8FA 4P9CA 4GGMX 2O7PA 2B1GA 4O8XB 3ZZMA 2B3JA 3SBGA 1VK9A 1WWRA 2G84A 4EG2A 1M9NA 5GAOA 4ILGC 4ZFRA 1THZA 4K1RA 4OCNA 3ZPGA 2ZNVA
chains in the Genus database with same CATH topology
4BGDC 1JTKA 4LD4A 1R5XA 1Z3AA 4OCMA 4NQLA 3DH1A 2O96A 4O8YA 2Z3IA 2RPZA 2KCQA 4OWPA 4MSQA 1MQ0A 1CTUA 1TIYA 2O3KA 4MSJA 2D30A 2A8NA 1WN6A 2OG4A 1WKQA 4P9DA 4OCLB 2P8RA 4LCNA 1ALNA 3ZEFB 1UX1A 2KKSA 4ZD5A 2NX8A 4MSDA 3DMOA 2Z3HA 1CTTA 2NYTA 2HXVA 4LD2A 4D10F 4ZFTA 5M59B 2D5NA 5M52C 2HVWA 3R2NA 3IJFX 4LCPA 2Z3GA 3E1UA 4JXEA 4OCNB 4LC5A 3MPZA 1OI0A 4OCMB 4I43B 1VQ2A 4O8YB 2G6VA 4O8XA 2ZNRA 3OCQA 3RZUA 4ZD4A 2PW9A 1WN5A 4HRQA 4F3WA 1OX7A 5DCAJ 2FR5A 5C2OA 3OJ6A 4WIFA 2O95A 3EX8A 3ZPCA 4QFTA 2P87A 4F7OA 4HRWA 4G3MA 1P6OA 4P9EA 4PQTA 4E0QA 2OBCA 4WIGA 1YSBA 2W4LA 1UAQA 4OWPB 4MSMA 1UX0A 4KITC 2B3ZA 4OCLA 2Z3JA 1ZABA 3RZVA 1RB7A 1R5TA 4MS7A 1YSDA 5CW6A 1UWZA 2QLCA 4LCOA 3G8QA 1AF2A 2HVVA 2FR6A 3B8FA 4P9CA 2O7PA 4O8XB 2B3JA 3SBGA 1WWRA 2G84A 4EG2A 5GAOA 4ILGC 4ZFRA 4K1RA 4OCNA 3ZPGA 2ZNVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BGD C;  1JTK A;  4LD4 A;  1R5X A;  1Z3A A;  4OCM A;  4NQL A;  3DH1 A;  2O96 A;  4O8Y A;  2Z3I A;  2RPZ A;  2KCQ A;  4OWP A;  4MSQ A;  1MQ0 A;  1CTU A;  1TIY A;  2O3K A;  4MSJ A;  2D30 A;  2A8N A;  1WN6 A;  2OG4 A;  1WKQ A;  4P9D A;  4OCL B;  2P8R A;  4LCN A;  1ALN A;  3ZEF B;  1UX1 A;  2KKS A;  4ZD5 A;  2NX8 A;  4MSD A;  3DMO A;  2Z3H A;  1CTT A;  2NYT A;  2HXV A;  4LD2 A;  4D10 F;  4ZFT A;  5M59 B;  2D5N A;  5M52 C;  2HVW A;  3R2N A;  3IJF X;  4LCP A;  2Z3G A;  3E1U A;  4JXE A;  4OCN B;  4LC5 A;  3MPZ A;  1OI0 A;  4OCM B;  4I43 B;  1VQ2 A;  4O8Y B;  2G6V A;  4O8X A;  2ZNR A;  3OCQ A;  3RZU A;  4ZD4 A;  2PW9 A;  1WN5 A;  4HRQ A;  4F3W A;  1OX7 A;  5DCA J;  2FR5 A;  5C2O A;  3OJ6 A;  4WIF A;  2O95 A;  3EX8 A;  3ZPC A;  4QFT A;  2P87 A;  4F7O A;  4HRW A;  4G3M A;  1P6O A;  4P9E A;  4PQT A;  4E0Q A;  2OBC A;  4WIG A;  1YSB A;  2W4L A;  1UAQ A;  4OWP B;  4MSM A;  1UX0 A;  4KIT C;  2B3Z A;  4OCL A;  2Z3J A;  1ZAB A;  3RZV A;  1RB7 A;  1R5T A;  4MS7 A;  1YSD A;  5CW6 A;  1UWZ A;  2QLC A;  4LCO A;  3G8Q A;  1AF2 A;  2HVV A;  2FR6 A;  3B8F A;  4P9C A;  2O7P A;  4O8X B;  2B3J A;  3SBG A;  1WWR A;  2G84 A;  4EG2 A;  5GAO A;  4ILG C;  4ZFR A;  4K1R A;  4OCN A;  3ZPG A;  2ZNV A; 
#chains in the Genus database with same CATH topology
 4BGD C;  1JTK A;  4LD4 A;  1R5X A;  1Z3A A;  4OCM A;  4NQL A;  3DH1 A;  2B1I A;  2O96 A;  4O8Y A;  1PL0 A;  2Z3I A;  2RPZ A;  2KCQ A;  4OWP A;  4MSQ A;  1MQ0 A;  1CTU A;  1TIY A;  2O3K A;  4MSJ A;  2D30 A;  2A8N A;  1WN6 A;  2OG4 A;  1WKQ A;  4P9D A;  4OCL B;  2P8R A;  4LCN A;  1ALN A;  3ZEF B;  1UX1 A;  4A1O A;  2KKS A;  1OZ0 A;  4ZD5 A;  2NX8 A;  4MSD A;  3DMO A;  1G8M A;  3VX8 A;  2Z3H A;  1CTT A;  2NYT A;  2HXV A;  4LD2 A;  4D10 F;  4ZFT A;  5M59 B;  2D5N A;  5M52 C;  2HVW A;  3R2N A;  3IJF X;  4LCP A;  2Z3G A;  3E1U A;  4JXE A;  4OCN B;  3BH1 A;  4LC5 A;  3MPZ A;  1OI0 A;  4OCM B;  4I43 B;  1VQ2 A;  4O8Y B;  2G6V A;  4O8X A;  2ZNR A;  1P4R A;  1ZCZ A;  3OCQ A;  3RZU A;  4ZD4 A;  2PW9 A;  1PKX A;  1WN5 A;  4HRQ A;  4F3W A;  2IU0 A;  1OX7 A;  5DCA J;  2FR5 A;  4EHI A;  5C2O A;  3OJ6 A;  4WIF A;  2O95 A;  3EX8 A;  3ZPC A;  4QFT A;  2P87 A;  4F7O A;  4HRW A;  4G3M A;  4J6E A;  1P6O A;  2IU3 A;  4P9E A;  4PQT A;  4E0Q A;  2OBC A;  4WIG A;  1YSB A;  2W4L A;  1UAQ A;  4OWP B;  4MSM A;  1UX0 A;  4KIT C;  2B3Z A;  4OCL A;  2Z3J A;  1ZAB A;  3RZV A;  1RB7 A;  1R5T A;  4MS7 A;  1YSD A;  5CW6 A;  1UWZ A;  2QLC A;  4LCO A;  3G8Q A;  1AF2 A;  2HVV A;  2FR6 A;  3B8F A;  4P9C A;  4GGM X;  2O7P A;  2B1G A;  4O8X B;  3ZZM A;  2B3J A;  3SBG A;  1VK9 A;  1WWR A;  2G84 A;  4EG2 A;  1M9N A;  5GAO A;  4ILG C;  4ZFR A;  1THZ A;  4K1R A;  4OCN A;  3ZPG A;  2ZNV A; 
#chains in the Genus database with same CATH homology
 4BGD C;  1JTK A;  4LD4 A;  1R5X A;  1Z3A A;  4OCM A;  4NQL A;  3DH1 A;  2O96 A;  4O8Y A;  2Z3I A;  2RPZ A;  2KCQ A;  4OWP A;  4MSQ A;  1MQ0 A;  1CTU A;  1TIY A;  2O3K A;  4MSJ A;  2D30 A;  2A8N A;  1WN6 A;  2OG4 A;  1WKQ A;  4P9D A;  4OCL B;  2P8R A;  4LCN A;  1ALN A;  3ZEF B;  1UX1 A;  2KKS A;  4ZD5 A;  2NX8 A;  4MSD A;  3DMO A;  2Z3H A;  1CTT A;  2NYT A;  2HXV A;  4LD2 A;  4D10 F;  4ZFT A;  5M59 B;  2D5N A;  5M52 C;  2HVW A;  3R2N A;  3IJF X;  4LCP A;  2Z3G A;  3E1U A;  4JXE A;  4OCN B;  4LC5 A;  3MPZ A;  1OI0 A;  4OCM B;  4I43 B;  1VQ2 A;  4O8Y B;  2G6V A;  4O8X A;  2ZNR A;  3OCQ A;  3RZU A;  4ZD4 A;  2PW9 A;  1WN5 A;  4HRQ A;  4F3W A;  1OX7 A;  5DCA J;  2FR5 A;  5C2O A;  3OJ6 A;  4WIF A;  2O95 A;  3EX8 A;  3ZPC A;  4QFT A;  2P87 A;  4F7O A;  4HRW A;  4G3M A;  1P6O A;  4P9E A;  4PQT A;  4E0Q A;  2OBC A;  4WIG A;  1YSB A;  2W4L A;  1UAQ A;  4OWP B;  4MSM A;  1UX0 A;  4KIT C;  2B3Z A;  4OCL A;  2Z3J A;  1ZAB A;  3RZV A;  1RB7 A;  1R5T A;  4MS7 A;  1YSD A;  5CW6 A;  1UWZ A;  2QLC A;  4LCO A;  3G8Q A;  1AF2 A;  2HVV A;  2FR6 A;  3B8F A;  4P9C A;  2O7P A;  4O8X B;  2B3J A;  3SBG A;  1WWR A;  2G84 A;  4EG2 A;  5GAO A;  4ILG C;  4ZFR A;  4K1R A;  4OCN A;  3ZPG A;  2ZNV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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