5M52C

Crystal structure of yeast brr2 full-lenght in complex with prp8 jab1 domain
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
266
structure length
266
Chain Sequence
SKNEWRKSAIANTLLYLRLKNIYVSADDFVEEQNVYVLPKNLLKKFIEISDVKIQVAAFIYGMSAKDHPKVKEIKTVVLVPQLGHVGSVQISNIPDIGDLPDTEGLELLGWIHTQTEELKFMAASEVATHSKLFADKKRDCIDISIFSTPGSVSLSAYNLTDEGYQWGEENKDIMNVLSEGFEPTFSTHAQLLLSDRITGNFIIPSGNVWNYTFMGTAFNQEGDYNFKYGIPLEFYNEMHRPVHFLQFSELAGDEELEAEQIDVFS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2.
pubmed doi rcsb
molecule tags Hydrolase
source organism Saccharomyces cerevisiae
molecule keywords Pre-mRNA-splicing helicase BRR2
total genus 60
structure length 266
sequence length 266
chains with identical sequence D
ec nomenclature
pdb deposition date 2016-10-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF08084 PROCT PROCT (NUC072) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.140.10 Alpha Beta 3-Layer(aba) Sandwich Cytidine Deaminase; domain 2 Cytidine Deaminase, domain 2 5m52C00
1YSDA 2Z3GA 1RB7A 4ZD4A 3ZPGA 3DMOA 3R2NA 4NQLA 4O8YB 3B8FA 2Z3IA 4O8XA 2D30A 4PQTA 2OBCA 2O96A 4HRQA 4OCNA 2NYTA 4BGDC 4MSJA 4OCMA 1UX1A 2B3JA 3OJ6A 1WN6A 3EX8A 1R5TA 2ZNVA 1R5XA 1YSBA 2A8NA 4LCNA 2G6VA 4LD4A 2HVWA 2W4LA 2P8RA 4ZD5A 4F7OA 4ZFRA 4G3MA 4LCPA 4OWPA 4LD2A 4I43B 2OG4A 1WKQA 4WIGA 3ZEFB 2O3KA 1MQ0A 2QLCA 2HXVA 4F3WA 2O95A 4OCLB 4ILGC 3ZPCA 3OCQA 3RZUA 1OI0A 4O8YA 5C2OA 4P9EA 2B3ZA 1JTKA 2HVVA 1TIYA 2KCQA 4O8XB 1CTUA 2FR6A 4OCNB 4MSDA 2FR5A 4MSMA 4HRWA 4LCOA 2NX8A 4EG2A 3MPZA 3IJFX 2RPZA 3DH1A 2Z3JA 2P87A 3SBGA 1ALNA 4D10F 1ZABA 1WN5A 4MSQA 2G84A 4KITC 2KKSA 1P6OA 5DCAJ 4E0QA 2ZNRA 1CTTA 2D5NA 4WIFA 4P9CA 4OCLA 5GAOA 4QFTA 5M59B 5CW6A 2Z3HA 4OCMB 4P9DA 3RZVA 2O7PA 5M52C 4K1RA 4MS7A 1WWRA 3E1UA 1Z3AA 4JXEA 1UAQA 1VQ2A 4ZFTA 2PW9A 1UX0A 4OWPB 1OX7A 1AF2A 1UWZA 4LC5A 3G8QA
chains in the Genus database with same CATH superfamily
1YSDA 2Z3GA 1RB7A 4ZD4A 3ZPGA 3DMOA 3R2NA 4A1OA 4NQLA 4O8YB 3B8FA 2Z3IA 2IU0A 4O8XA 2D30A 4PQTA 2OBCA 2O96A 4HRQA 4OCNA 2NYTA 4BGDC 4MSJA 4OCMA 1UX1A 2B3JA 3OJ6A 1WN6A 3EX8A 1R5TA 2ZNVA 1R5XA 1YSBA 2A8NA 4LCNA 2G6VA 3VX8A 4LD4A 2HVWA 1PKXA 2W4LA 2P8RA 4ZD5A 1OZ0A 4F7OA 4ZFRA 4G3MA 4LCPA 4OWPA 4LD2A 4I43B 2OG4A 4J6EA 1WKQA 4WIGA 3ZEFB 2O3KA 1MQ0A 2IU3A 4EHIA 2QLCA 2HXVA 4F3WA 1P4RA 2O95A 4OCLB 4ILGC 3ZPCA 2B1IA 3OCQA 1M9NA 3RZUA 1OI0A 4O8YA 5C2OA 4P9EA 2B3ZA 1JTKA 2HVVA 1TIYA 2KCQA 4O8XB 1CTUA 2FR6A 4OCNB 1ZCZA 4MSDA 2FR5A 4MSMA 4HRWA 4LCOA 2NX8A 4EG2A 3MPZA 3IJFX 2B1GA 2RPZA 3DH1A 2Z3JA 2P87A 3SBGA 1ALNA 4D10F 1ZABA 1WN5A 4MSQA 1PL0A 2G84A 4KITC 2KKSA 1P6OA 5DCAJ 4E0QA 2ZNRA 1CTTA 4GGMX 2D5NA 4WIFA 4P9CA 3ZZMA 4OCLA 5GAOA 4QFTA 5M59B 5CW6A 2Z3HA 4OCMB 4P9DA 3RZVA 2O7PA 5M52C 4K1RA 4MS7A 1WWRA 3E1UA 1Z3AA 4JXEA 1UAQA 3BH1A 1VQ2A 4ZFTA 2PW9A 1UX0A 1G8MA 4OWPB 1VK9A 1OX7A 1AF2A 1UWZA 4LC5A 3G8QA 1THZA
chains in the Genus database with same CATH topology
1YSDA 2Z3GA 1RB7A 4ZD4A 3ZPGA 3DMOA 3R2NA 4NQLA 4O8YB 3B8FA 2Z3IA 4O8XA 2D30A 4PQTA 2OBCA 2O96A 4HRQA 4OCNA 2NYTA 4BGDC 4MSJA 4OCMA 1UX1A 2B3JA 3OJ6A 1WN6A 3EX8A 1R5TA 2ZNVA 1R5XA 1YSBA 2A8NA 4LCNA 2G6VA 4LD4A 2HVWA 2W4LA 2P8RA 4ZD5A 4F7OA 4ZFRA 4G3MA 4LCPA 4OWPA 4LD2A 4I43B 2OG4A 1WKQA 4WIGA 3ZEFB 2O3KA 1MQ0A 2QLCA 2HXVA 4F3WA 2O95A 4OCLB 4ILGC 3ZPCA 3OCQA 3RZUA 1OI0A 4O8YA 5C2OA 4P9EA 2B3ZA 1JTKA 2HVVA 1TIYA 2KCQA 4O8XB 1CTUA 2FR6A 4OCNB 4MSDA 2FR5A 4MSMA 4HRWA 4LCOA 2NX8A 4EG2A 3MPZA 3IJFX 2RPZA 3DH1A 2Z3JA 2P87A 3SBGA 1ALNA 4D10F 1ZABA 1WN5A 4MSQA 2G84A 4KITC 2KKSA 1P6OA 5DCAJ 4E0QA 2ZNRA 1CTTA 2D5NA 4WIFA 4P9CA 4OCLA 5GAOA 4QFTA 5M59B 5CW6A 2Z3HA 4OCMB 4P9DA 3RZVA 2O7PA 5M52C 4K1RA 4MS7A 1WWRA 3E1UA 1Z3AA 4JXEA 1UAQA 1VQ2A 4ZFTA 2PW9A 1UX0A 4OWPB 1OX7A 1AF2A 1UWZA 4LC5A 3G8QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YSD A;  2Z3G A;  1RB7 A;  4ZD4 A;  3ZPG A;  3DMO A;  3R2N A;  4NQL A;  4O8Y B;  3B8F A;  2Z3I A;  4O8X A;  2D30 A;  4PQT A;  2OBC A;  2O96 A;  4HRQ A;  4OCN A;  2NYT A;  4BGD C;  4MSJ A;  4OCM A;  1UX1 A;  2B3J A;  3OJ6 A;  1WN6 A;  3EX8 A;  1R5T A;  2ZNV A;  1R5X A;  1YSB A;  2A8N A;  4LCN A;  2G6V A;  4LD4 A;  2HVW A;  2W4L A;  2P8R A;  4ZD5 A;  4F7O A;  4ZFR A;  4G3M A;  4LCP A;  4OWP A;  4LD2 A;  4I43 B;  2OG4 A;  1WKQ A;  4WIG A;  3ZEF B;  2O3K A;  1MQ0 A;  2QLC A;  2HXV A;  4F3W A;  2O95 A;  4OCL B;  4ILG C;  3ZPC A;  3OCQ A;  3RZU A;  1OI0 A;  4O8Y A;  5C2O A;  4P9E A;  2B3Z A;  1JTK A;  2HVV A;  1TIY A;  2KCQ A;  4O8X B;  1CTU A;  2FR6 A;  4OCN B;  4MSD A;  2FR5 A;  4MSM A;  4HRW A;  4LCO A;  2NX8 A;  4EG2 A;  3MPZ A;  3IJF X;  2RPZ A;  3DH1 A;  2Z3J A;  2P87 A;  3SBG A;  1ALN A;  4D10 F;  1ZAB A;  1WN5 A;  4MSQ A;  2G84 A;  4KIT C;  2KKS A;  1P6O A;  5DCA J;  4E0Q A;  2ZNR A;  1CTT A;  2D5N A;  4WIF A;  4P9C A;  4OCL A;  5GAO A;  4QFT A;  5M59 B;  5CW6 A;  2Z3H A;  4OCM B;  4P9D A;  3RZV A;  2O7P A;  5M52 C;  4K1R A;  4MS7 A;  1WWR A;  3E1U A;  1Z3A A;  4JXE A;  1UAQ A;  1VQ2 A;  4ZFT A;  2PW9 A;  1UX0 A;  4OWP B;  1OX7 A;  1AF2 A;  1UWZ A;  4LC5 A;  3G8Q A; 
#chains in the Genus database with same CATH topology
 1YSD A;  2Z3G A;  1RB7 A;  4ZD4 A;  3ZPG A;  3DMO A;  3R2N A;  4A1O A;  4NQL A;  4O8Y B;  3B8F A;  2Z3I A;  2IU0 A;  4O8X A;  2D30 A;  4PQT A;  2OBC A;  2O96 A;  4HRQ A;  4OCN A;  2NYT A;  4BGD C;  4MSJ A;  4OCM A;  1UX1 A;  2B3J A;  3OJ6 A;  1WN6 A;  3EX8 A;  1R5T A;  2ZNV A;  1R5X A;  1YSB A;  2A8N A;  4LCN A;  2G6V A;  3VX8 A;  4LD4 A;  2HVW A;  1PKX A;  2W4L A;  2P8R A;  4ZD5 A;  1OZ0 A;  4F7O A;  4ZFR A;  4G3M A;  4LCP A;  4OWP A;  4LD2 A;  4I43 B;  2OG4 A;  4J6E A;  1WKQ A;  4WIG A;  3ZEF B;  2O3K A;  1MQ0 A;  2IU3 A;  4EHI A;  2QLC A;  2HXV A;  4F3W A;  1P4R A;  2O95 A;  4OCL B;  4ILG C;  3ZPC A;  2B1I A;  3OCQ A;  1M9N A;  3RZU A;  1OI0 A;  4O8Y A;  5C2O A;  4P9E A;  2B3Z A;  1JTK A;  2HVV A;  1TIY A;  2KCQ A;  4O8X B;  1CTU A;  2FR6 A;  4OCN B;  1ZCZ A;  4MSD A;  2FR5 A;  4MSM A;  4HRW A;  4LCO A;  2NX8 A;  4EG2 A;  3MPZ A;  3IJF X;  2B1G A;  2RPZ A;  3DH1 A;  2Z3J A;  2P87 A;  3SBG A;  1ALN A;  4D10 F;  1ZAB A;  1WN5 A;  4MSQ A;  1PL0 A;  2G84 A;  4KIT C;  2KKS A;  1P6O A;  5DCA J;  4E0Q A;  2ZNR A;  1CTT A;  4GGM X;  2D5N A;  4WIF A;  4P9C A;  3ZZM A;  4OCL A;  5GAO A;  4QFT A;  5M59 B;  5CW6 A;  2Z3H A;  4OCM B;  4P9D A;  3RZV A;  2O7P A;  5M52 C;  4K1R A;  4MS7 A;  1WWR A;  3E1U A;  1Z3A A;  4JXE A;  1UAQ A;  3BH1 A;  1VQ2 A;  4ZFT A;  2PW9 A;  1UX0 A;  1G8M A;  4OWP B;  1VK9 A;  1OX7 A;  1AF2 A;  1UWZ A;  4LC5 A;  3G8Q A;  1THZ A; 
#chains in the Genus database with same CATH homology
 1YSD A;  2Z3G A;  1RB7 A;  4ZD4 A;  3ZPG A;  3DMO A;  3R2N A;  4NQL A;  4O8Y B;  3B8F A;  2Z3I A;  4O8X A;  2D30 A;  4PQT A;  2OBC A;  2O96 A;  4HRQ A;  4OCN A;  2NYT A;  4BGD C;  4MSJ A;  4OCM A;  1UX1 A;  2B3J A;  3OJ6 A;  1WN6 A;  3EX8 A;  1R5T A;  2ZNV A;  1R5X A;  1YSB A;  2A8N A;  4LCN A;  2G6V A;  4LD4 A;  2HVW A;  2W4L A;  2P8R A;  4ZD5 A;  4F7O A;  4ZFR A;  4G3M A;  4LCP A;  4OWP A;  4LD2 A;  4I43 B;  2OG4 A;  1WKQ A;  4WIG A;  3ZEF B;  2O3K A;  1MQ0 A;  2QLC A;  2HXV A;  4F3W A;  2O95 A;  4OCL B;  4ILG C;  3ZPC A;  3OCQ A;  3RZU A;  1OI0 A;  4O8Y A;  5C2O A;  4P9E A;  2B3Z A;  1JTK A;  2HVV A;  1TIY A;  2KCQ A;  4O8X B;  1CTU A;  2FR6 A;  4OCN B;  4MSD A;  2FR5 A;  4MSM A;  4HRW A;  4LCO A;  2NX8 A;  4EG2 A;  3MPZ A;  3IJF X;  2RPZ A;  3DH1 A;  2Z3J A;  2P87 A;  3SBG A;  1ALN A;  4D10 F;  1ZAB A;  1WN5 A;  4MSQ A;  2G84 A;  4KIT C;  2KKS A;  1P6O A;  5DCA J;  4E0Q A;  2ZNR A;  1CTT A;  2D5N A;  4WIF A;  4P9C A;  4OCL A;  5GAO A;  4QFT A;  5M59 B;  5CW6 A;  2Z3H A;  4OCM B;  4P9D A;  3RZV A;  2O7P A;  5M52 C;  4K1R A;  4MS7 A;  1WWR A;  3E1U A;  1Z3A A;  4JXE A;  1UAQ A;  1VQ2 A;  4ZFT A;  2PW9 A;  1UX0 A;  4OWP B;  1OX7 A;  1AF2 A;  1UWZ A;  4LC5 A;  3G8Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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