5M59B

Crystal structure of chaetomium thermophilum brr2 helicase core in complex with prp8 jab1 domain
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
266
structure length
266
Chain Sequence
TEWRTRAIATSNLRTRANNMYVAPVDNDVDDITYVMPKNILKKFITIADLRVQVAGFLYGCSPADNDQVKEIRCIVMVPQIGGNRSVQLPQHLPQHEMLKGLEPLGLIHTMAGNELPYMSPADVTTHAKLVDAHPSWKNQNTLTVTVAFTPGSVSLSAWALTPLGYKWGVENKDPNVDNPQGFTTTMGERRQLLLSDKFKGFFLVPDTGKWNYSFMGSSFSGIEKKPYHVKLDTPLPFYSEQHRPIHFTSFNELEDIWVDRADNFA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2.
pubmed doi rcsb
molecule tags Splicing
source organism Chaetomium thermophilum
molecule keywords Putative pre-mRNA splicing factor
total genus 50
structure length 266
sequence length 266
chains with identical sequence D, F, H
ec nomenclature
pdb deposition date 2016-10-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF08084 PROCT PROCT (NUC072) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.140.10 Alpha Beta 3-Layer(aba) Sandwich Cytidine Deaminase; domain 2 Cytidine Deaminase, domain 2 5m59B00
3G8QA 4E0QA 2HXVA 2B3JA 3OCQA 3IJFX 4LCOA 4ZFRA 1YSBA 4NQLA 3B8FA 1WWRA 4OCMA 2O3KA 1CTTA 4QFTA 2RPZA 1TIYA 1ZABA 5CW6A 2Z3HA 2D30A 5GAOA 4D10F 4F3WA 2NYTA 1OI0A 1OX7A 2FR5A 3OJ6A 4LC5A 3RZUA 1CTUA 3DMOA 1UX1A 4OWPA 4O8YB 1WN5A 5DCAJ 2Z3JA 1R5XA 4JXEA 5M59B 4F7OA 5M52C 4MSDA 1MQ0A 3ZPCA 3MPZA 2Z3GA 4MSMA 1UX0A 4G3MA 2ZNVA 3E1UA 4WIGA 4OWPB 2P8RA 4OCLA 4LD4A 3R2NA 2W4LA 2OBCA 2QLCA 1R5TA 4I43B 4OCNA 2FR6A 2KKSA 4LD2A 1JTKA 4OCMB 4ZD5A 2NX8A 4LCNA 2D5NA 2P87A 4HRQA 4EG2A 2OG4A 2Z3IA 2HVWA 1UAQA 2A8NA 4MS7A 3RZVA 4OCNB 1Z3AA 2KCQA 4P9EA 4MSQA 1VQ2A 1UWZA 4ZD4A 3SBGA 4P9DA 2O96A 1WKQA 4HRWA 4MSJA 2O7PA 1YSDA 2O95A 4O8XA 2ZNRA 4P9CA 1P6OA 4PQTA 3ZPGA 3ZEFB 4OCLB 4ILGC 2PW9A 2G84A 2G6VA 4KITC 1ALNA 2B3ZA 4LCPA 4O8XB 4O8YA 4ZFTA 5C2OA 3DH1A 1RB7A 1WN6A 3EX8A 2HVVA 4WIFA 4BGDC 1AF2A 4K1RA
chains in the Genus database with same CATH superfamily
3G8QA 4E0QA 2HXVA 2B3JA 2IU3A 3OCQA 3IJFX 4LCOA 4ZFRA 1THZA 1YSBA 4NQLA 3B8FA 1WWRA 4OCMA 2O3KA 1CTTA 4QFTA 2RPZA 1TIYA 1ZABA 5CW6A 2Z3HA 2D30A 5GAOA 4D10F 4F3WA 2NYTA 1OI0A 1OX7A 2FR5A 3OJ6A 4LC5A 4J6EA 3RZUA 1CTUA 3DMOA 1UX1A 4OWPA 4O8YB 1WN5A 5DCAJ 2Z3JA 1R5XA 4JXEA 5M59B 4F7OA 5M52C 4MSDA 1MQ0A 3ZPCA 3MPZA 2Z3GA 4MSMA 1UX0A 4G3MA 2ZNVA 3E1UA 4WIGA 4OWPB 2P8RA 1PL0A 4LD4A 4OCLA 3R2NA 2W4LA 2OBCA 2QLCA 1R5TA 1OZ0A 4I43B 4OCNA 4GGMX 2FR6A 2KKSA 4LD2A 1JTKA 4OCMB 4ZD5A 2NX8A 4LCNA 2D5NA 2P87A 4HRQA 4EG2A 2OG4A 2Z3IA 2HVWA 1G8MA 1UAQA 2A8NA 4MS7A 3RZVA 4OCNB 1Z3AA 2KCQA 4P9EA 4MSQA 1PKXA 1VQ2A 1UWZA 4ZD4A 3SBGA 4P9DA 2O96A 1M9NA 1WKQA 4HRWA 1VK9A 4MSJA 2O7PA 1P4RA 1YSDA 2O95A 4O8XA 2ZNRA 4P9CA 1P6OA 4PQTA 3VX8A 3ZPGA 3ZZMA 3ZEFB 4OCLB 4ILGC 4A1OA 2PW9A 3BH1A 2G84A 2G6VA 2B1IA 4KITC 1ALNA 2B3ZA 4LCPA 4O8XB 4O8YA 4ZFTA 5C2OA 3DH1A 1RB7A 1WN6A 3EX8A 4EHIA 1ZCZA 2HVVA 4WIFA 2IU0A 4BGDC 2B1GA 1AF2A 4K1RA
chains in the Genus database with same CATH topology
3G8QA 4E0QA 2HXVA 2B3JA 3OCQA 3IJFX 4LCOA 4ZFRA 1YSBA 4NQLA 3B8FA 1WWRA 4OCMA 2O3KA 1CTTA 4QFTA 2RPZA 1TIYA 1ZABA 5CW6A 2Z3HA 2D30A 5GAOA 4D10F 4F3WA 2NYTA 1OI0A 1OX7A 2FR5A 3OJ6A 4LC5A 3RZUA 1CTUA 3DMOA 1UX1A 4OWPA 4O8YB 1WN5A 5DCAJ 2Z3JA 1R5XA 4JXEA 5M59B 4F7OA 5M52C 4MSDA 1MQ0A 3ZPCA 3MPZA 2Z3GA 4MSMA 1UX0A 4G3MA 2ZNVA 3E1UA 4WIGA 4OWPB 2P8RA 4OCLA 4LD4A 3R2NA 2W4LA 2OBCA 2QLCA 1R5TA 4I43B 4OCNA 2FR6A 2KKSA 4LD2A 1JTKA 4OCMB 4ZD5A 2NX8A 4LCNA 2D5NA 2P87A 4HRQA 4EG2A 2OG4A 2Z3IA 2HVWA 1UAQA 2A8NA 4MS7A 3RZVA 4OCNB 1Z3AA 2KCQA 4P9EA 4MSQA 1VQ2A 1UWZA 4ZD4A 3SBGA 4P9DA 2O96A 1WKQA 4HRWA 4MSJA 2O7PA 1YSDA 2O95A 4O8XA 2ZNRA 4P9CA 1P6OA 4PQTA 3ZPGA 3ZEFB 4OCLB 4ILGC 2PW9A 2G84A 2G6VA 4KITC 1ALNA 2B3ZA 4LCPA 4O8XB 4O8YA 4ZFTA 5C2OA 3DH1A 1RB7A 1WN6A 3EX8A 2HVVA 4WIFA 4BGDC 1AF2A 4K1RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G8Q A;  4E0Q A;  2HXV A;  2B3J A;  3OCQ A;  3IJF X;  4LCO A;  4ZFR A;  1YSB A;  4NQL A;  3B8F A;  1WWR A;  4OCM A;  2O3K A;  1CTT A;  4QFT A;  2RPZ A;  1TIY A;  1ZAB A;  5CW6 A;  2Z3H A;  2D30 A;  5GAO A;  4D10 F;  4F3W A;  2NYT A;  1OI0 A;  1OX7 A;  2FR5 A;  3OJ6 A;  4LC5 A;  3RZU A;  1CTU A;  3DMO A;  1UX1 A;  4OWP A;  4O8Y B;  1WN5 A;  5DCA J;  2Z3J A;  1R5X A;  4JXE A;  5M59 B;  4F7O A;  5M52 C;  4MSD A;  1MQ0 A;  3ZPC A;  3MPZ A;  2Z3G A;  4MSM A;  1UX0 A;  4G3M A;  2ZNV A;  3E1U A;  4WIG A;  4OWP B;  2P8R A;  4OCL A;  4LD4 A;  3R2N A;  2W4L A;  2OBC A;  2QLC A;  1R5T A;  4I43 B;  4OCN A;  2FR6 A;  2KKS A;  4LD2 A;  1JTK A;  4OCM B;  4ZD5 A;  2NX8 A;  4LCN A;  2D5N A;  2P87 A;  4HRQ A;  4EG2 A;  2OG4 A;  2Z3I A;  2HVW A;  1UAQ A;  2A8N A;  4MS7 A;  3RZV A;  4OCN B;  1Z3A A;  2KCQ A;  4P9E A;  4MSQ A;  1VQ2 A;  1UWZ A;  4ZD4 A;  3SBG A;  4P9D A;  2O96 A;  1WKQ A;  4HRW A;  4MSJ A;  2O7P A;  1YSD A;  2O95 A;  4O8X A;  2ZNR A;  4P9C A;  1P6O A;  4PQT A;  3ZPG A;  3ZEF B;  4OCL B;  4ILG C;  2PW9 A;  2G84 A;  2G6V A;  4KIT C;  1ALN A;  2B3Z A;  4LCP A;  4O8X B;  4O8Y A;  4ZFT A;  5C2O A;  3DH1 A;  1RB7 A;  1WN6 A;  3EX8 A;  2HVV A;  4WIF A;  4BGD C;  1AF2 A;  4K1R A; 
#chains in the Genus database with same CATH topology
 3G8Q A;  4E0Q A;  2HXV A;  2B3J A;  2IU3 A;  3OCQ A;  3IJF X;  4LCO A;  4ZFR A;  1THZ A;  1YSB A;  4NQL A;  3B8F A;  1WWR A;  4OCM A;  2O3K A;  1CTT A;  4QFT A;  2RPZ A;  1TIY A;  1ZAB A;  5CW6 A;  2Z3H A;  2D30 A;  5GAO A;  4D10 F;  4F3W A;  2NYT A;  1OI0 A;  1OX7 A;  2FR5 A;  3OJ6 A;  4LC5 A;  4J6E A;  3RZU A;  1CTU A;  3DMO A;  1UX1 A;  4OWP A;  4O8Y B;  1WN5 A;  5DCA J;  2Z3J A;  1R5X A;  4JXE A;  5M59 B;  4F7O A;  5M52 C;  4MSD A;  1MQ0 A;  3ZPC A;  3MPZ A;  2Z3G A;  4MSM A;  1UX0 A;  4G3M A;  2ZNV A;  3E1U A;  4WIG A;  4OWP B;  2P8R A;  1PL0 A;  4LD4 A;  4OCL A;  3R2N A;  2W4L A;  2OBC A;  2QLC A;  1R5T A;  1OZ0 A;  4I43 B;  4OCN A;  4GGM X;  2FR6 A;  2KKS A;  4LD2 A;  1JTK A;  4OCM B;  4ZD5 A;  2NX8 A;  4LCN A;  2D5N A;  2P87 A;  4HRQ A;  4EG2 A;  2OG4 A;  2Z3I A;  2HVW A;  1G8M A;  1UAQ A;  2A8N A;  4MS7 A;  3RZV A;  4OCN B;  1Z3A A;  2KCQ A;  4P9E A;  4MSQ A;  1PKX A;  1VQ2 A;  1UWZ A;  4ZD4 A;  3SBG A;  4P9D A;  2O96 A;  1M9N A;  1WKQ A;  4HRW A;  1VK9 A;  4MSJ A;  2O7P A;  1P4R A;  1YSD A;  2O95 A;  4O8X A;  2ZNR A;  4P9C A;  1P6O A;  4PQT A;  3VX8 A;  3ZPG A;  3ZZM A;  3ZEF B;  4OCL B;  4ILG C;  4A1O A;  2PW9 A;  3BH1 A;  2G84 A;  2G6V A;  2B1I A;  4KIT C;  1ALN A;  2B3Z A;  4LCP A;  4O8X B;  4O8Y A;  4ZFT A;  5C2O A;  3DH1 A;  1RB7 A;  1WN6 A;  3EX8 A;  4EHI A;  1ZCZ A;  2HVV A;  4WIF A;  2IU0 A;  4BGD C;  2B1G A;  1AF2 A;  4K1R A; 
#chains in the Genus database with same CATH homology
 3G8Q A;  4E0Q A;  2HXV A;  2B3J A;  3OCQ A;  3IJF X;  4LCO A;  4ZFR A;  1YSB A;  4NQL A;  3B8F A;  1WWR A;  4OCM A;  2O3K A;  1CTT A;  4QFT A;  2RPZ A;  1TIY A;  1ZAB A;  5CW6 A;  2Z3H A;  2D30 A;  5GAO A;  4D10 F;  4F3W A;  2NYT A;  1OI0 A;  1OX7 A;  2FR5 A;  3OJ6 A;  4LC5 A;  3RZU A;  1CTU A;  3DMO A;  1UX1 A;  4OWP A;  4O8Y B;  1WN5 A;  5DCA J;  2Z3J A;  1R5X A;  4JXE A;  5M59 B;  4F7O A;  5M52 C;  4MSD A;  1MQ0 A;  3ZPC A;  3MPZ A;  2Z3G A;  4MSM A;  1UX0 A;  4G3M A;  2ZNV A;  3E1U A;  4WIG A;  4OWP B;  2P8R A;  4OCL A;  4LD4 A;  3R2N A;  2W4L A;  2OBC A;  2QLC A;  1R5T A;  4I43 B;  4OCN A;  2FR6 A;  2KKS A;  4LD2 A;  1JTK A;  4OCM B;  4ZD5 A;  2NX8 A;  4LCN A;  2D5N A;  2P87 A;  4HRQ A;  4EG2 A;  2OG4 A;  2Z3I A;  2HVW A;  1UAQ A;  2A8N A;  4MS7 A;  3RZV A;  4OCN B;  1Z3A A;  2KCQ A;  4P9E A;  4MSQ A;  1VQ2 A;  1UWZ A;  4ZD4 A;  3SBG A;  4P9D A;  2O96 A;  1WKQ A;  4HRW A;  4MSJ A;  2O7P A;  1YSD A;  2O95 A;  4O8X A;  2ZNR A;  4P9C A;  1P6O A;  4PQT A;  3ZPG A;  3ZEF B;  4OCL B;  4ILG C;  2PW9 A;  2G84 A;  2G6V A;  4KIT C;  1ALN A;  2B3Z A;  4LCP A;  4O8X B;  4O8Y A;  4ZFT A;  5C2O A;  3DH1 A;  1RB7 A;  1WN6 A;  3EX8 A;  2HVV A;  4WIF A;  4BGD C;  1AF2 A;  4K1R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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