3PIOW

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
55
structure length
55
Chain Sequence
MKIKLVRSVIGRPGNQVKTVQALGLRKIGDSREVSDTPAVRGMVKTVKHLLEVQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 11
structure length 55
sequence length 55
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3pioW00
1VQOW 1QVFV 1M1KX 1YI2W 5GADa 1QVGV 3CCUW 4UY8Z 2OTJW 1K9MX 2OTLW 3CCJW 4WFNW 1YJWW 2ZJRW 3CCSW 3G4SW 2QA4W 5DM7W 4IOAW 1VQ4W 2ZJPW 1Q7YX 1VQ5W 1W2BV 1VQ6W 1NJIX 1VQ7W 5HL7W 3CC4W 1Q86X 1YJ9W 3CC7W 1BXYA 3CMAW 1K73X 3CCRW 3CPWV 4IOCW 2ZJQW 4WF9W 1VQNW 1JJ2V 3OW2V 1VQMW 1VQPW 3PIOW 3CCEW 3CCMW 4U67W 1YHQW 5JVGW 3CF5W 1YJNW 3CCQW 5JVHW 1YITW 5GAHa 3I56W 1VQ8W 3J7ZZ 3CCLW 4WCEW 3CC2W 4IO9W 1VQLW 1KC8X 3CMEW 3PIPW 3DLLW 3CD6W 3G6EW 1KQSV 5DM6W 1VQKW 1Q81X 1M90X 1Q82X 1K8AX 3CXCV 5GAGa 1N8RX 5GAEa 3CCVW 4WFAW 3G71W 1YIJW 1VQ9W 1KD1X 4WFBW 2QEXW 1S72W 3I55W
chains in the Genus database with same CATH superfamily
1VQOW 3O1FA 1QVFV 1RQUA 1M1KX 3G1BA 1YI2W 5GADa 1QVGV 3CCUW 4UY8Z 3W7SA 2OTJW 1K9MX 2OTLW 3CCJW 5M19A 4WFNW 1YJWW 3O2HA 2ZJRW 3CCSW 3G4SW 2QA4W 2W9RA 5DM7W 4IOAW 4CPKA 1DD4A 1VQ4W 1MWTA 3DNJA 1R6QC 2ZJPW 1Q7YX 1MBXC 1VQ5W 1W2BV 1VQ6W 3ZG0A 1MWSA 3W7TA 4CJNA 1NJIX 1VQ7W 5HL7W 3CC4W 1Q86X 1YJ9W 3CC7W 3O1FB 3W7UA 1BXYA 3CMAW 1K73X 3CCRW 3CPWV 1CTFA 4YKAA 4IOCW 3ZFZA 2ZJQW 3GW1A 4WF9W 1VQNW 2WA8A 1MBUC 1JJ2V 3OW2V 3D3IA 1VQMW 3W7XA 1VQPW 3PIOW 3CCEW 1MG9A 3CCMW 4U67W 3O2BA 3W7WA 1YHQW 5JVGW 3CF5W 1YJNW 3CCQW 1LZWA 5JVHW 1YITW 4BL2A 5GAHa 3I56W 1R6OC 1VQ8W 3J7ZZ 1MWUA 3CCLW 4WCEW 3CC2W 4IO9W 5CA3A 1VQLW 1KC8X 5M1AA 1MWRA 3PIPW 3CMEW 3DLLW 3CD6W 3G6EW 3GQ1A 4YJMA 1KQSV 3O2OA 5M18A 5DM6W 1MBVB 1RQVA 3G3PA 1VQKW 1Q81X 1M90X 4YJXA 1Q82X 1K8AX 4DKIA 1DD3A 3CXCV 5GAGa 4BL3A 5GW7A 5GAEa 1N8RX 3CCVW 4WFAW 3GQ0A 3G19A 3G71W 1YIJW 1VQ9W 1KD1X 2WA9A 4WFBW 1RQSA 2QEXW 1S72W 3ZG5A 3I55W 1VQQA
chains in the Genus database with same CATH topology
1VQOW 1QVFV 1M1KX 1YI2W 5GADa 1QVGV 3CCUW 4UY8Z 2OTJW 1K9MX 2OTLW 3CCJW 4WFNW 1YJWW 2ZJRW 3CCSW 3G4SW 2QA4W 5DM7W 4IOAW 1VQ4W 2ZJPW 1Q7YX 1VQ5W 1W2BV 1VQ6W 1NJIX 1VQ7W 5HL7W 3CC4W 1Q86X 1YJ9W 3CC7W 1BXYA 3CMAW 1K73X 3CCRW 3CPWV 4IOCW 2ZJQW 4WF9W 1VQNW 1JJ2V 3OW2V 1VQMW 1VQPW 3PIOW 3CCEW 3CCMW 4U67W 1YHQW 5JVGW 3CF5W 1YJNW 3CCQW 5JVHW 1YITW 5GAHa 3I56W 1VQ8W 3J7ZZ 3CCLW 4WCEW 3CC2W 4IO9W 1VQLW 1KC8X 3CMEW 3PIPW 3DLLW 3CD6W 3G6EW 1KQSV 5DM6W 1VQKW 1Q81X 1M90X 1Q82X 1K8AX 3CXCV 5GAGa 1N8RX 5GAEa 3CCVW 4WFAW 3G71W 1YIJW 1VQ9W 1KD1X 4WFBW 2QEXW 1S72W 3I55W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VQO W;  1QVF V;  1M1K X;  1YI2 W;  5GAD a;  1QVG V;  3CCU W;  4UY8 Z;  2OTJ W;  1K9M X;  2OTL W;  3CCJ W;  4WFN W;  1YJW W;  2ZJR W;  3CCS W;  3G4S W;  2QA4 W;  5DM7 W;  4IOA W;  1VQ4 W;  2ZJP W;  1Q7Y X;  1VQ5 W;  1W2B V;  1VQ6 W;  1NJI X;  1VQ7 W;  5HL7 W;  3CC4 W;  1Q86 X;  1YJ9 W;  3CC7 W;  1BXY A;  3CMA W;  1K73 X;  3CCR W;  3CPW V;  4IOC W;  2ZJQ W;  4WF9 W;  1VQN W;  1JJ2 V;  3OW2 V;  1VQM W;  1VQP W;  3PIO W;  3CCE W;  3CCM W;  4U67 W;  1YHQ W;  5JVG W;  3CF5 W;  1YJN W;  3CCQ W;  5JVH W;  1YIT W;  5GAH a;  3I56 W;  1VQ8 W;  3J7Z Z;  3CCL W;  4WCE W;  3CC2 W;  4IO9 W;  1VQL W;  1KC8 X;  3CME W;  3PIP W;  3DLL W;  3CD6 W;  3G6E W;  1KQS V;  5DM6 W;  1VQK W;  1Q81 X;  1M90 X;  1Q82 X;  1K8A X;  3CXC V;  5GAG a;  1N8R X;  5GAE a;  3CCV W;  4WFA W;  3G71 W;  1YIJ W;  1VQ9 W;  1KD1 X;  4WFB W;  2QEX W;  1S72 W;  3I55 W; 
#chains in the Genus database with same CATH topology
 1VQO W;  3O1F A;  1QVF V;  1RQU A;  1M1K X;  3G1B A;  1YI2 W;  5GAD a;  1QVG V;  3CCU W;  4UY8 Z;  3W7S A;  2OTJ W;  1K9M X;  2OTL W;  3CCJ W;  5M19 A;  4WFN W;  1YJW W;  3O2H A;  2ZJR W;  3CCS W;  3G4S W;  2QA4 W;  2W9R A;  5DM7 W;  4IOA W;  4CPK A;  1DD4 A;  1VQ4 W;  1MWT A;  3DNJ A;  1R6Q C;  2ZJP W;  1Q7Y X;  1MBX C;  1VQ5 W;  1W2B V;  1VQ6 W;  3ZG0 A;  1MWS A;  3W7T A;  4CJN A;  1NJI X;  1VQ7 W;  5HL7 W;  3CC4 W;  1Q86 X;  1YJ9 W;  3CC7 W;  3O1F B;  3W7U A;  1BXY A;  3CMA W;  1K73 X;  3CCR W;  3CPW V;  1CTF A;  4YKA A;  4IOC W;  3ZFZ A;  2ZJQ W;  3GW1 A;  4WF9 W;  1VQN W;  2WA8 A;  1MBU C;  1JJ2 V;  3OW2 V;  3D3I A;  1VQM W;  3W7X A;  1VQP W;  3PIO W;  3CCE W;  1MG9 A;  3CCM W;  4U67 W;  3O2B A;  3W7W A;  1YHQ W;  5JVG W;  3CF5 W;  1YJN W;  3CCQ W;  1LZW A;  5JVH W;  1YIT W;  4BL2 A;  5GAH a;  3I56 W;  1R6O C;  1VQ8 W;  3J7Z Z;  1MWU A;  3CCL W;  4WCE W;  3CC2 W;  4IO9 W;  5CA3 A;  1VQL W;  1KC8 X;  5M1A A;  1MWR A;  3PIP W;  3CME W;  3DLL W;  3CD6 W;  3G6E W;  3GQ1 A;  4YJM A;  1KQS V;  3O2O A;  5M18 A;  5DM6 W;  1MBV B;  1RQV A;  3G3P A;  1VQK W;  1Q81 X;  1M90 X;  4YJX A;  1Q82 X;  1K8A X;  4DKI A;  1DD3 A;  3CXC V;  5GAG a;  4BL3 A;  5GW7 A;  5GAE a;  1N8R X;  3CCV W;  4WFA W;  3GQ0 A;  3G19 A;  3G71 W;  1YIJ W;  1VQ9 W;  1KD1 X;  2WA9 A;  4WFB W;  1RQS A;  2QEX W;  1S72 W;  3ZG5 A;  3I55 W;  1VQQ A; 
#chains in the Genus database with same CATH homology
 1VQO W;  1QVF V;  1M1K X;  1YI2 W;  5GAD a;  1QVG V;  3CCU W;  4UY8 Z;  2OTJ W;  1K9M X;  2OTL W;  3CCJ W;  4WFN W;  1YJW W;  2ZJR W;  3CCS W;  3G4S W;  2QA4 W;  5DM7 W;  4IOA W;  1VQ4 W;  2ZJP W;  1Q7Y X;  1VQ5 W;  1W2B V;  1VQ6 W;  1NJI X;  1VQ7 W;  5HL7 W;  3CC4 W;  1Q86 X;  1YJ9 W;  3CC7 W;  1BXY A;  3CMA W;  1K73 X;  3CCR W;  3CPW V;  4IOC W;  2ZJQ W;  4WF9 W;  1VQN W;  1JJ2 V;  3OW2 V;  1VQM W;  1VQP W;  3PIO W;  3CCE W;  3CCM W;  4U67 W;  1YHQ W;  5JVG W;  3CF5 W;  1YJN W;  3CCQ W;  5JVH W;  1YIT W;  5GAH a;  3I56 W;  1VQ8 W;  3J7Z Z;  3CCL W;  4WCE W;  3CC2 W;  4IO9 W;  1VQL W;  1KC8 X;  3CME W;  3PIP W;  3DLL W;  3CD6 W;  3G6E W;  1KQS V;  5DM6 W;  1VQK W;  1Q81 X;  1M90 X;  1Q82 X;  1K8A X;  3CXC V;  5GAG a;  1N8R X;  5GAE a;  3CCV W;  4WFA W;  3G71 W;  1YIJ W;  1VQ9 W;  1KD1 X;  4WFB W;  2QEX W;  1S72 W;  3I55 W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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