3PIPW

Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
55
structure length
55
Chain Sequence
MKIKLVRSVIGRPGNQVKTVQALGLRKIGDSREVSDTPAVRGMVKTVKHLLEVQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords RIBOSOMAL 23S RNA
total genus 11
structure length 55
sequence length 55
ec nomenclature
pdb deposition date 2010-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
W PF00327 Ribosomal_L30 Ribosomal protein L30p/L7e
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1390.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein L30; Chain: A, Ribosomal protein L30, ferredoxin-like fold domain 3pipW00
3I56W 1K9MX 1Q86X 3G71W 1N8RX 5HL7W 1W2BV 1Q81X 1YI2W 4WFBW 2OTLW 1VQOW 1VQ6W 5DM6W 1YHQW 3CD6W 1YJWW 1Q82X 3CPWV 3CF5W 4WFAW 2ZJPW 5GAGa 5GADa 2OTJW 3CCSW 3J7ZZ 1KD1X 1VQ8W 1S72W 3CC2W 3CCEW 3CC4W 1YJNW 1YIJW 4UY8Z 1KQSV 1YITW 2QEXW 4IOAW 1BXYA 3CMEW 5GAHa 1VQ4W 4WF9W 3PIPW 1K8AX 1VQ5W 1NJIX 1VQMW 3PIOW 3CCQW 3I55W 3CXCV 4WCEW 4WFNW 1M1KX 4IO9W 3DLLW 5DM7W 5JVGW 1VQLW 3CCLW 2ZJRW 3G6EW 5JVHW 3CMAW 3CCVW 3OW2V 2QA4W 5GAEa 1JJ2V 1K73X 3CCMW 1YJ9W 2ZJQW 1VQNW 3CCRW 1KC8X 1QVFV 3CC7W 4IOCW 1VQKW 3G4SW 1QVGV 3CCUW 3CCJW 1VQPW 1VQ7W 1VQ9W 1Q7YX 1M90X 4U67W
chains in the Genus database with same CATH superfamily
3G3PA 4BL2A 3I56W 1K9MX 1Q86X 3G71W 1N8RX 5HL7W 1W2BV 1Q81X 1YI2W 4WFBW 2OTLW 1VQOW 1VQ6W 3GQ0A 3O2HA 3W7SA 5DM6W 1YHQW 5CA3A 4DKIA 3ZFZA 3CD6W 1YJWW 1Q82X 4YJXA 3CPWV 1R6QC 4WFAW 2ZJPW 5GAGa 1MWTA 5GADa 3CF5W 2OTJW 5M18A 3CCSW 1MBUC 3J7ZZ 1KD1X 3G1BA 3W7XA 3W7TA 1VQ8W 4YKAA 1S72W 3CC2W 4CPKA 3CCEW 3CC4W 1YJNW 3W7UA 1YIJW 1DD3A 4UY8Z 3O2OA 1KQSV 1YITW 3ZG5A 2QEXW 4BL3A 4IOAW 1BXYA 3D3IA 1MG9A 1DD4A 3CMEW 5GAHa 1VQ4W 4WF9W 3PIPW 1K8AX 1MWRA 2W9RA 3O2BA 5M19A 1RQSA 1VQ5W 1NJIX 1CTFA 1VQMW 3O1FB 3PIOW 3CCQW 3I55W 3CXCV 4CJNA 4WFNW 4WCEW 4IO9W 3DLLW 1M1KX 1LZWA 5DM7W 5JVGW 1VQLW 3CCLW 2ZJRW 3G6EW 3W7WA 5JVHW 1RQUA 2WA9A 3CMAW 3DNJA 3CCVW 1VQQA 3OW2V 1MWUA 3ZG0A 2QA4W 5GAEa 4YJMA 3O1FA 5M1AA 1JJ2V 1MBXC 3GQ1A 1K73X 3CCMW 1YJ9W 1MBVB 2ZJQW 1VQNW 1RQVA 3CCRW 1KC8X 1QVFV 1R6OC 3CC7W 4IOCW 1VQKW 3G4SW 1QVGV 3CCUW 3CCJW 1VQPW 1MWSA 2WA8A 5GW7A 1VQ7W 1VQ9W 1Q7YX 1M90X 3G19A 4U67W 3GW1A
chains in the Genus database with same CATH topology
3I56W 1K9MX 1Q86X 3G71W 1N8RX 5HL7W 1W2BV 1Q81X 1YI2W 4WFBW 2OTLW 1VQOW 1VQ6W 5DM6W 1YHQW 3CD6W 1YJWW 1Q82X 3CPWV 3CF5W 4WFAW 2ZJPW 5GAGa 5GADa 2OTJW 3CCSW 3J7ZZ 1KD1X 1VQ8W 1S72W 3CC2W 3CCEW 3CC4W 1YJNW 1YIJW 4UY8Z 1KQSV 1YITW 2QEXW 4IOAW 1BXYA 3CMEW 5GAHa 1VQ4W 4WF9W 3PIPW 1K8AX 1VQ5W 1NJIX 1VQMW 3PIOW 3CCQW 3I55W 3CXCV 4WCEW 4WFNW 1M1KX 4IO9W 3DLLW 5DM7W 5JVGW 1VQLW 3CCLW 2ZJRW 3G6EW 5JVHW 3CMAW 3CCVW 3OW2V 2QA4W 5GAEa 1JJ2V 1K73X 3CCMW 1YJ9W 2ZJQW 1VQNW 3CCRW 1KC8X 1QVFV 3CC7W 4IOCW 1VQKW 3G4SW 1QVGV 3CCUW 3CCJW 1VQPW 1VQ7W 1VQ9W 1Q7YX 1M90X 4U67W
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I56 W;  1K9M X;  1Q86 X;  3G71 W;  1N8R X;  5HL7 W;  1W2B V;  1Q81 X;  1YI2 W;  4WFB W;  2OTL W;  1VQO W;  1VQ6 W;  5DM6 W;  1YHQ W;  3CD6 W;  1YJW W;  1Q82 X;  3CPW V;  3CF5 W;  4WFA W;  2ZJP W;  5GAG a;  5GAD a;  2OTJ W;  3CCS W;  3J7Z Z;  1KD1 X;  1VQ8 W;  1S72 W;  3CC2 W;  3CCE W;  3CC4 W;  1YJN W;  1YIJ W;  4UY8 Z;  1KQS V;  1YIT W;  2QEX W;  4IOA W;  1BXY A;  3CME W;  5GAH a;  1VQ4 W;  4WF9 W;  3PIP W;  1K8A X;  1VQ5 W;  1NJI X;  1VQM W;  3PIO W;  3CCQ W;  3I55 W;  3CXC V;  4WCE W;  4WFN W;  1M1K X;  4IO9 W;  3DLL W;  5DM7 W;  5JVG W;  1VQL W;  3CCL W;  2ZJR W;  3G6E W;  5JVH W;  3CMA W;  3CCV W;  3OW2 V;  2QA4 W;  5GAE a;  1JJ2 V;  1K73 X;  3CCM W;  1YJ9 W;  2ZJQ W;  1VQN W;  3CCR W;  1KC8 X;  1QVF V;  3CC7 W;  4IOC W;  1VQK W;  3G4S W;  1QVG V;  3CCU W;  3CCJ W;  1VQP W;  1VQ7 W;  1VQ9 W;  1Q7Y X;  1M90 X;  4U67 W; 
#chains in the Genus database with same CATH topology
 3G3P A;  4BL2 A;  3I56 W;  1K9M X;  1Q86 X;  3G71 W;  1N8R X;  5HL7 W;  1W2B V;  1Q81 X;  1YI2 W;  4WFB W;  2OTL W;  1VQO W;  1VQ6 W;  3GQ0 A;  3O2H A;  3W7S A;  5DM6 W;  1YHQ W;  5CA3 A;  4DKI A;  3ZFZ A;  3CD6 W;  1YJW W;  1Q82 X;  4YJX A;  3CPW V;  1R6Q C;  4WFA W;  2ZJP W;  5GAG a;  1MWT A;  5GAD a;  3CF5 W;  2OTJ W;  5M18 A;  3CCS W;  1MBU C;  3J7Z Z;  1KD1 X;  3G1B A;  3W7X A;  3W7T A;  1VQ8 W;  4YKA A;  1S72 W;  3CC2 W;  4CPK A;  3CCE W;  3CC4 W;  1YJN W;  3W7U A;  1YIJ W;  1DD3 A;  4UY8 Z;  3O2O A;  1KQS V;  1YIT W;  3ZG5 A;  2QEX W;  4BL3 A;  4IOA W;  1BXY A;  3D3I A;  1MG9 A;  1DD4 A;  3CME W;  5GAH a;  1VQ4 W;  4WF9 W;  3PIP W;  1K8A X;  1MWR A;  2W9R A;  3O2B A;  5M19 A;  1RQS A;  1VQ5 W;  1NJI X;  1CTF A;  1VQM W;  3O1F B;  3PIO W;  3CCQ W;  3I55 W;  3CXC V;  4CJN A;  4WFN W;  4WCE W;  4IO9 W;  3DLL W;  1M1K X;  1LZW A;  5DM7 W;  5JVG W;  1VQL W;  3CCL W;  2ZJR W;  3G6E W;  3W7W A;  5JVH W;  1RQU A;  2WA9 A;  3CMA W;  3DNJ A;  3CCV W;  1VQQ A;  3OW2 V;  1MWU A;  3ZG0 A;  2QA4 W;  5GAE a;  4YJM A;  3O1F A;  5M1A A;  1JJ2 V;  1MBX C;  3GQ1 A;  1K73 X;  3CCM W;  1YJ9 W;  1MBV B;  2ZJQ W;  1VQN W;  1RQV A;  3CCR W;  1KC8 X;  1QVF V;  1R6O C;  3CC7 W;  4IOC W;  1VQK W;  3G4S W;  1QVG V;  3CCU W;  3CCJ W;  1VQP W;  1MWS A;  2WA8 A;  5GW7 A;  1VQ7 W;  1VQ9 W;  1Q7Y X;  1M90 X;  3G19 A;  4U67 W;  3GW1 A; 
#chains in the Genus database with same CATH homology
 3I56 W;  1K9M X;  1Q86 X;  3G71 W;  1N8R X;  5HL7 W;  1W2B V;  1Q81 X;  1YI2 W;  4WFB W;  2OTL W;  1VQO W;  1VQ6 W;  5DM6 W;  1YHQ W;  3CD6 W;  1YJW W;  1Q82 X;  3CPW V;  3CF5 W;  4WFA W;  2ZJP W;  5GAG a;  5GAD a;  2OTJ W;  3CCS W;  3J7Z Z;  1KD1 X;  1VQ8 W;  1S72 W;  3CC2 W;  3CCE W;  3CC4 W;  1YJN W;  1YIJ W;  4UY8 Z;  1KQS V;  1YIT W;  2QEX W;  4IOA W;  1BXY A;  3CME W;  5GAH a;  1VQ4 W;  4WF9 W;  3PIP W;  1K8A X;  1VQ5 W;  1NJI X;  1VQM W;  3PIO W;  3CCQ W;  3I55 W;  3CXC V;  4WCE W;  4WFN W;  1M1K X;  4IO9 W;  3DLL W;  5DM7 W;  5JVG W;  1VQL W;  3CCL W;  2ZJR W;  3G6E W;  5JVH W;  3CMA W;  3CCV W;  3OW2 V;  2QA4 W;  5GAE a;  1JJ2 V;  1K73 X;  3CCM W;  1YJ9 W;  2ZJQ W;  1VQN W;  3CCR W;  1KC8 X;  1QVF V;  3CC7 W;  4IOC W;  1VQK W;  3G4S W;  1QVG V;  3CCU W;  3CCJ W;  1VQP W;  1VQ7 W;  1VQ9 W;  1Q7Y X;  1M90 X;  4U67 W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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