1A37 | Genus

Total Genus 71

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	71
sequence length	228
structure length	195
Chain Sequence	MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNAAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKIRLGLALNFSVFYYACSLAKTAFDEAIADDSTLIMQLLRDNLTLW

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Complex (signal transduction/peptide)
source organism	Bos taurus
publication title	14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove. pubmed doi rcsb
molecule keywords	14-3-3 PROTEIN ZETA
total genus	71
structure length	195
sequence length	228
chains with identical sequence	B
ec nomenclature
pdb deposition date	1998-01-28

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00244	14-3-3	14-3-3 protein

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.190.20	Mainly Alpha	Up-down Bundle	Delta-Endotoxin; domain 1	14-3-3 domain	1a37A00

4IEAA 2NPMA 3SPRA 5HF3A 4DHPA 4QLIA 3UALA 3E6YA 4Y5IA 3IQVA 4JDDA 4DAUA 3P1RA 1A37A 2V7DA 5EXAA 2B05A 4DATA 5D3FA 3P1QA 4N7YA 3UZDA 3EFZA 1A38A 4DHOA 2C1NA 1YZ5A 4F7RA 4N84A 3SMLA 4E2EA 5BY9A 4DHUA 1YWTA 5D3EA 4IHLA 2C1JA 2BTPA 5BTVA 4FJ3A 2C74A 2WH0A 3T0MA 1O9CA 5LHOA 3IQJA 1O9FA 3SMMA 5IQPA 3O8IA 4ZDRA 4BG6A 3M50A 2O02A 4GNTA 4ZQ0A 3IQUA 1A4OA 1O9DA 5EWZA 4WRQA 4J6SA 5LVZA 4DHTA 3LW1A 3UX0A 3SMKA 4HKCA 4FL5A 3P1NA 4DHRA 5D2DA 4Y32A 4DHNA 5J31A 3SMNA 4JC3A 2O98A 3P1OA 3RDHA 3UBWA 4DHQA 5LU1A 3CU8A 4N7GA 3NKXA 1QJAA 4DHSA 1IB1A 4Y3BA 4O46A 3U9XA 4DHMA 4DNKA 4FR3A 2BQ0A 2O8PA 2C23A 5LU2A 3M51A 3AXYC 4DX0A 5F74A 1O9EA 5LX2A 3P1PA 3MHRA 2C63A 3SMOA 3T0LA 3P1SA 3SP5A 1QJBA 2BR9A
chains in the Genus database with same CATH superfamily

1URJA 4IEAA 2NPMA 3SPRA 5HF3A 4DHPA 4QLIA 3UALA 3E6YA 4Y5IA 1DLCA 3IQVA 4JDDA 4DAUA 3P1RA 1A37A 2V7DA 5EXAA 2B05A 4DATA 5D3FA 3P1QA 4N7YA 3UZDA 3EFZA 1A38A 4DHOA 2C1NA 1YZ5A 4F7RA 4N84A 3SMLA 3ZHEB 4E2EA 5BY9A 3CQCA 4DHUA 1YWTA 5D3EA 4IHLA 2C1JA 2BTPA 5BTVA 3X0UA 4FJ3A 2C74A 2WH0A 3T0MA 1O9CA 5LHOA 4D8MA 3IQJA 1W99A 1O9FA 3CQGA 3SMMA 5IQPA 3O8IA 4ZDRA 4BG6A 3M50A 4QX3A 2O02A 4GNTA 4ZQ0A 3IQUA 1A4OA 1O9DA 5EWZA 4WRQA 4J6SA 5LVZA 4DHTA 4W8JA 3LW1A 3UX0A 3SMKA 4HKCA 4FL5A 1CIYA 3P1NA 4DHRA 5D2DA 4Y32A 1I5PA 4DHNA 5J31A 3SMNA 4JC3A 2O98A 3P1OA 3RDHA 3UBWA 4DHQA 4MOAA 5LU1A 3CU8A 4N7GA 2C9KA 3NKXA 1QJAA 4DHSA 1IB1A 4Y3BA 4O46A 1S2XA 3U9XA 4DHMA 4DNKA 4FR3A 2BQ0A 2O8PA 2C23A 5LU2A 3I4RA 4ARYA 3M51A 3AXYC 1JI6A 4DX0A 4QX1A 5F74A 1O9EA 5LX2A 3P1PA 3MHRA 2C63A 3SMOA 3T0LA 4QX2A 3P1SA 4QX0A 4ARXA 3SP5A 3EB7A 1QJBA 2BR9A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4IEA A;  2NPM A;  3SPR A;  5HF3 A;  4DHP A;  4QLI A;  3UAL A;  3E6Y A;  4Y5I A;  3IQV A;  4JDD A;  4DAU A;  3P1R A;  1A37 A;  2V7D A;  5EXA A;  2B05 A;  4DAT A;  5D3F A;  3P1Q A;  4N7Y A;  3UZD A;  3EFZ A;  1A38 A;  4DHO A;  2C1N A;  1YZ5 A;  4F7R A;  4N84 A;  3SML A;  4E2E A;  5BY9 A;  4DHU A;  1YWT A;  5D3E A;  4IHL A;  2C1J A;  2BTP A;  5BTV A;  4FJ3 A;  2C74 A;  2WH0 A;  3T0M A;  1O9C A;  5LHO A;  3IQJ A;  1O9F A;  3SMM A;  5IQP A;  3O8I A;  4ZDR A;  4BG6 A;  3M50 A;  2O02 A;  4GNT A;  4ZQ0 A;  3IQU A;  1A4O A;  1O9D A;  5EWZ A;  4WRQ A;  4J6S A;  5LVZ A;  4DHT A;  3LW1 A;  3UX0 A;  3SMK A;  4HKC A;  4FL5 A;  3P1N A;  4DHR A;  5D2D A;  4Y32 A;  4DHN A;  5J31 A;  3SMN A;  4JC3 A;  2O98 A;  3P1O A;  3RDH A;  3UBW A;  4DHQ A;  5LU1 A;  3CU8 A;  4N7G A;  3NKX A;  1QJA A;  4DHS A;  1IB1 A;  4Y3B A;  4O46 A;  3U9X A;  4DHM A;  4DNK A;  4FR3 A;  2BQ0 A;  2O8P A;  2C23 A;  5LU2 A;  3M51 A;  3AXY C;  4DX0 A;  5F74 A;  1O9E A;  5LX2 A;  3P1P A;  3MHR A;  2C63 A;  3SMO A;  3T0L A;  3P1S A;  3SP5 A;  1QJB A;  2BR9 A; 
#chains in the Genus database with same CATH topology
 1URJ A;  4IEA A;  2NPM A;  3SPR A;  5HF3 A;  4DHP A;  4QLI A;  3UAL A;  3E6Y A;  4Y5I A;  1DLC A;  3IQV A;  4JDD A;  4DAU A;  3P1R A;  1A37 A;  2V7D A;  5EXA A;  2B05 A;  4DAT A;  5D3F A;  3P1Q A;  4N7Y A;  3UZD A;  3EFZ A;  1A38 A;  4DHO A;  2C1N A;  1YZ5 A;  4F7R A;  4N84 A;  3SML A;  3ZHE B;  4E2E A;  5BY9 A;  3CQC A;  4DHU A;  1YWT A;  5D3E A;  4IHL A;  2C1J A;  2BTP A;  5BTV A;  3X0U A;  4FJ3 A;  2C74 A;  2WH0 A;  3T0M A;  1O9C A;  5LHO A;  4D8M A;  3IQJ A;  1W99 A;  1O9F A;  3CQG A;  3SMM A;  5IQP A;  3O8I A;  4ZDR A;  4BG6 A;  3M50 A;  4QX3 A;  2O02 A;  4GNT A;  4ZQ0 A;  3IQU A;  1A4O A;  1O9D A;  5EWZ A;  4WRQ A;  4J6S A;  5LVZ A;  4DHT A;  4W8J A;  3LW1 A;  3UX0 A;  3SMK A;  4HKC A;  4FL5 A;  1CIY A;  3P1N A;  4DHR A;  5D2D A;  4Y32 A;  1I5P A;  4DHN A;  5J31 A;  3SMN A;  4JC3 A;  2O98 A;  3P1O A;  3RDH A;  3UBW A;  4DHQ A;  4MOA A;  5LU1 A;  3CU8 A;  4N7G A;  2C9K A;  3NKX A;  1QJA A;  4DHS A;  1IB1 A;  4Y3B A;  4O46 A;  1S2X A;  3U9X A;  4DHM A;  4DNK A;  4FR3 A;  2BQ0 A;  2O8P A;  2C23 A;  5LU2 A;  3I4R A;  4ARY A;  3M51 A;  3AXY C;  1JI6 A;  4DX0 A;  4QX1 A;  5F74 A;  1O9E A;  5LX2 A;  3P1P A;  3MHR A;  2C63 A;  3SMO A;  3T0L A;  4QX2 A;  3P1S A;  4QX0 A;  4ARX A;  3SP5 A;  3EB7 A;  1QJB A;  2BR9 A; 
#chains in the Genus database with same CATH homology
 4IEA A;  2NPM A;  3SPR A;  5HF3 A;  4DHP A;  4QLI A;  3UAL A;  3E6Y A;  4Y5I A;  3IQV A;  4JDD A;  4DAU A;  3P1R A;  1A37 A;  2V7D A;  5EXA A;  2B05 A;  4DAT A;  5D3F A;  3P1Q A;  4N7Y A;  3UZD A;  3EFZ A;  1A38 A;  4DHO A;  2C1N A;  1YZ5 A;  4F7R A;  4N84 A;  3SML A;  4E2E A;  5BY9 A;  4DHU A;  1YWT A;  5D3E A;  4IHL A;  2C1J A;  2BTP A;  5BTV A;  4FJ3 A;  2C74 A;  2WH0 A;  3T0M A;  1O9C A;  5LHO A;  3IQJ A;  1O9F A;  3SMM A;  5IQP A;  3O8I A;  4ZDR A;  4BG6 A;  3M50 A;  2O02 A;  4GNT A;  4ZQ0 A;  3IQU A;  1A4O A;  1O9D A;  5EWZ A;  4WRQ A;  4J6S A;  5LVZ A;  4DHT A;  3LW1 A;  3UX0 A;  3SMK A;  4HKC A;  4FL5 A;  3P1N A;  4DHR A;  5D2D A;  4Y32 A;  4DHN A;  5J31 A;  3SMN A;  4JC3 A;  2O98 A;  3P1O A;  3RDH A;  3UBW A;  4DHQ A;  5LU1 A;  3CU8 A;  4N7G A;  3NKX A;  1QJA A;  4DHS A;  1IB1 A;  4Y3B A;  4O46 A;  3U9X A;  4DHM A;  4DNK A;  4FR3 A;  2BQ0 A;  2O8P A;  2C23 A;  5LU2 A;  3M51 A;  3AXY C;  4DX0 A;  5F74 A;  1O9E A;  5LX2 A;  3P1P A;  3MHR A;  2C63 A;  3SMO A;  3T0L A;  3P1S A;  3SP5 A;  1QJB A;  2BR9 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1A37A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations