4F7RA

Crystal structure of 14-3-3 protein from giardia intestinalis
Total Genus 100
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
236
structure length
236
Chain Sequence
AEAFTREDYVFMAQLNENAERYDEMVETMRKISGMEGELSDKERNLLSVAYKNVIGPRRAAWRIVSSIEAKEKGRQKPNAKRIEQIRVYRQKIEKELSDICNDILKLLQEQFVPRSTNADAKVFYYKMQGDYYRYLAEYSSGEDKEKIAGSALNAYNSAFEISQQLPPTHPIRLGLALNFSVFYYEILASPDRACELARKAFDAAITDLDKLTEESYKDSTLIMQLLRDNLNLWVT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The Crystal Structure of Giardia duodenalis 14-3-3 in the Apo Form: When Protein Post-Translational Modifications Make the Difference.
pubmed doi rcsb
molecule tags Signaling protein
source organism Giardia intestinalis
molecule keywords 14-3-3 protein
total genus 100
structure length 236
sequence length 236
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2012-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 4f7rA00
2NPMA 4HKCA 5IQPA 4DHSA 4Y5IA 3P1OA 3P1PA 4JDDA 3E6YA 2O8PA 3T0LA 4BG6A 1A4OA 4DHMA 4DHOA 4DATA 4WRQA 3M50A 4Y32A 2C1JA 1QJBA 3SMOA 3UALA 3UX0A 1IB1A 4DAUA 4JC3A 5BY9A 4F7RA 5LX2A 3NKXA 3SPRA 5LHOA 5LU1A 5D3EA 1O9CA 3IQJA 5EXAA 2C63A 3M51A 4FR3A 3O8IA 3IQUA 4FJ3A 4J6SA 4N84A 5HF3A 1QJAA 3SMMA 5D3FA 3P1QA 4ZQ0A 3T0MA 4DHTA 5BTVA 3RDHA 1A38A 1O9EA 4E2EA 3SP5A 2BQ0A 5J31A 2C74A 3MHRA 3SMNA 1YZ5A 4DHPA 3IQVA 2C23A 4GNTA 4ZDRA 1YWTA 2C1NA 4DHQA 1A37A 2B05A 4IHLA 5D2DA 4DX0A 2O98A 3CU8A 3U9XA 3SMLA 4QLIA 4IEAA 5EWZA 5F74A 4O46A 2WH0A 3LW1A 4Y3BA 2V7DA 4FL5A 5LVZA 4DHRA 3P1NA 4DHNA 1O9DA 3SMKA 3P1RA 4DNKA 2O02A 3EFZA 4N7YA 3UZDA 3P1SA 5LU2A 3UBWA 2BTPA 3AXYC 2BR9A 4DHUA 4N7GA 1O9FA
chains in the Genus database with same CATH superfamily
2NPMA 2C9KA 4HKCA 5IQPA 4DHSA 4QX0A 4Y5IA 3P1OA 3P1PA 3CQCA 4JDDA 3E6YA 2O8PA 3T0LA 4BG6A 1A4OA 4DHMA 4DHOA 4DATA 4WRQA 3M50A 4Y32A 2C1JA 1QJBA 3SMOA 3UALA 1W99A 3UX0A 1URJA 1IB1A 3ZHEB 4DAUA 4JC3A 5BY9A 4F7RA 5LX2A 3NKXA 3SPRA 5LHOA 5LU1A 5D3EA 1O9CA 3I4RA 3IQJA 5EXAA 2C63A 3M51A 1DLCA 4FR3A 3O8IA 3IQUA 4FJ3A 4J6SA 4N84A 4QX2A 5HF3A 1QJAA 3SMMA 5D3FA 3P1QA 4ZQ0A 3T0MA 4DHTA 3CQGA 5BTVA 3RDHA 1A38A 1O9EA 3X0UA 4E2EA 3SP5A 2BQ0A 5J31A 2C74A 3MHRA 3SMNA 1YZ5A 4DHPA 4W8JA 3IQVA 2C23A 4ARXA 4GNTA 4ZDRA 1YWTA 2C1NA 4DHQA 1A37A 2B05A 4IHLA 5D2DA 4QX3A 4DX0A 2O98A 3CU8A 3U9XA 3SMLA 4QLIA 4IEAA 5EWZA 5F74A 4O46A 2WH0A 3LW1A 4Y3BA 2V7DA 1I5PA 1JI6A 3EB7A 4FL5A 5LVZA 4DHRA 3P1NA 4ARYA 1CIYA 4DHNA 1O9DA 3SMKA 4QX1A 3P1RA 4DNKA 2O02A 3EFZA 4N7YA 3UZDA 4D8MA 3P1SA 5LU2A 3UBWA 2BTPA 3AXYC 1S2XA 2BR9A 4DHUA 4N7GA 4MOAA 1O9FA
chains in the Genus database with same CATH topology
2NPMA 4HKCA 5IQPA 4DHSA 4Y5IA 3P1OA 3P1PA 4JDDA 3E6YA 2O8PA 3T0LA 4BG6A 1A4OA 4DHMA 4DHOA 4DATA 4WRQA 3M50A 4Y32A 2C1JA 1QJBA 3SMOA 3UALA 3UX0A 1IB1A 4DAUA 4JC3A 5BY9A 4F7RA 5LX2A 3NKXA 3SPRA 5LHOA 5LU1A 5D3EA 1O9CA 3IQJA 5EXAA 2C63A 3M51A 4FR3A 3O8IA 3IQUA 4FJ3A 4J6SA 4N84A 5HF3A 1QJAA 3SMMA 5D3FA 3P1QA 4ZQ0A 3T0MA 4DHTA 5BTVA 3RDHA 1A38A 1O9EA 4E2EA 3SP5A 2BQ0A 5J31A 2C74A 3MHRA 3SMNA 1YZ5A 4DHPA 3IQVA 2C23A 4GNTA 4ZDRA 1YWTA 2C1NA 4DHQA 1A37A 2B05A 4IHLA 5D2DA 4DX0A 2O98A 3CU8A 3U9XA 3SMLA 4QLIA 4IEAA 5EWZA 5F74A 4O46A 2WH0A 3LW1A 4Y3BA 2V7DA 4FL5A 5LVZA 4DHRA 3P1NA 4DHNA 1O9DA 3SMKA 3P1RA 4DNKA 2O02A 3EFZA 4N7YA 3UZDA 3P1SA 5LU2A 3UBWA 2BTPA 3AXYC 2BR9A 4DHUA 4N7GA 1O9FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NPM A;  4HKC A;  5IQP A;  4DHS A;  4Y5I A;  3P1O A;  3P1P A;  4JDD A;  3E6Y A;  2O8P A;  3T0L A;  4BG6 A;  1A4O A;  4DHM A;  4DHO A;  4DAT A;  4WRQ A;  3M50 A;  4Y32 A;  2C1J A;  1QJB A;  3SMO A;  3UAL A;  3UX0 A;  1IB1 A;  4DAU A;  4JC3 A;  5BY9 A;  4F7R A;  5LX2 A;  3NKX A;  3SPR A;  5LHO A;  5LU1 A;  5D3E A;  1O9C A;  3IQJ A;  5EXA A;  2C63 A;  3M51 A;  4FR3 A;  3O8I A;  3IQU A;  4FJ3 A;  4J6S A;  4N84 A;  5HF3 A;  1QJA A;  3SMM A;  5D3F A;  3P1Q A;  4ZQ0 A;  3T0M A;  4DHT A;  5BTV A;  3RDH A;  1A38 A;  1O9E A;  4E2E A;  3SP5 A;  2BQ0 A;  5J31 A;  2C74 A;  3MHR A;  3SMN A;  1YZ5 A;  4DHP A;  3IQV A;  2C23 A;  4GNT A;  4ZDR A;  1YWT A;  2C1N A;  4DHQ A;  1A37 A;  2B05 A;  4IHL A;  5D2D A;  4DX0 A;  2O98 A;  3CU8 A;  3U9X A;  3SML A;  4QLI A;  4IEA A;  5EWZ A;  5F74 A;  4O46 A;  2WH0 A;  3LW1 A;  4Y3B A;  2V7D A;  4FL5 A;  5LVZ A;  4DHR A;  3P1N A;  4DHN A;  1O9D A;  3SMK A;  3P1R A;  4DNK A;  2O02 A;  3EFZ A;  4N7Y A;  3UZD A;  3P1S A;  5LU2 A;  3UBW A;  2BTP A;  3AXY C;  2BR9 A;  4DHU A;  4N7G A;  1O9F A; 
#chains in the Genus database with same CATH topology
 2NPM A;  2C9K A;  4HKC A;  5IQP A;  4DHS A;  4QX0 A;  4Y5I A;  3P1O A;  3P1P A;  3CQC A;  4JDD A;  3E6Y A;  2O8P A;  3T0L A;  4BG6 A;  1A4O A;  4DHM A;  4DHO A;  4DAT A;  4WRQ A;  3M50 A;  4Y32 A;  2C1J A;  1QJB A;  3SMO A;  3UAL A;  1W99 A;  3UX0 A;  1URJ A;  1IB1 A;  3ZHE B;  4DAU A;  4JC3 A;  5BY9 A;  4F7R A;  5LX2 A;  3NKX A;  3SPR A;  5LHO A;  5LU1 A;  5D3E A;  1O9C A;  3I4R A;  3IQJ A;  5EXA A;  2C63 A;  3M51 A;  1DLC A;  4FR3 A;  3O8I A;  3IQU A;  4FJ3 A;  4J6S A;  4N84 A;  4QX2 A;  5HF3 A;  1QJA A;  3SMM A;  5D3F A;  3P1Q A;  4ZQ0 A;  3T0M A;  4DHT A;  3CQG A;  5BTV A;  3RDH A;  1A38 A;  1O9E A;  3X0U A;  4E2E A;  3SP5 A;  2BQ0 A;  5J31 A;  2C74 A;  3MHR A;  3SMN A;  1YZ5 A;  4DHP A;  4W8J A;  3IQV A;  2C23 A;  4ARX A;  4GNT A;  4ZDR A;  1YWT A;  2C1N A;  4DHQ A;  1A37 A;  2B05 A;  4IHL A;  5D2D A;  4QX3 A;  4DX0 A;  2O98 A;  3CU8 A;  3U9X A;  3SML A;  4QLI A;  4IEA A;  5EWZ A;  5F74 A;  4O46 A;  2WH0 A;  3LW1 A;  4Y3B A;  2V7D A;  1I5P A;  1JI6 A;  3EB7 A;  4FL5 A;  5LVZ A;  4DHR A;  3P1N A;  4ARY A;  1CIY A;  4DHN A;  1O9D A;  3SMK A;  4QX1 A;  3P1R A;  4DNK A;  2O02 A;  3EFZ A;  4N7Y A;  3UZD A;  4D8M A;  3P1S A;  5LU2 A;  3UBW A;  2BTP A;  3AXY C;  1S2X A;  2BR9 A;  4DHU A;  4N7G A;  4MOA A;  1O9F A; 
#chains in the Genus database with same CATH homology
 2NPM A;  4HKC A;  5IQP A;  4DHS A;  4Y5I A;  3P1O A;  3P1P A;  4JDD A;  3E6Y A;  2O8P A;  3T0L A;  4BG6 A;  1A4O A;  4DHM A;  4DHO A;  4DAT A;  4WRQ A;  3M50 A;  4Y32 A;  2C1J A;  1QJB A;  3SMO A;  3UAL A;  3UX0 A;  1IB1 A;  4DAU A;  4JC3 A;  5BY9 A;  4F7R A;  5LX2 A;  3NKX A;  3SPR A;  5LHO A;  5LU1 A;  5D3E A;  1O9C A;  3IQJ A;  5EXA A;  2C63 A;  3M51 A;  4FR3 A;  3O8I A;  3IQU A;  4FJ3 A;  4J6S A;  4N84 A;  5HF3 A;  1QJA A;  3SMM A;  5D3F A;  3P1Q A;  4ZQ0 A;  3T0M A;  4DHT A;  5BTV A;  3RDH A;  1A38 A;  1O9E A;  4E2E A;  3SP5 A;  2BQ0 A;  5J31 A;  2C74 A;  3MHR A;  3SMN A;  1YZ5 A;  4DHP A;  3IQV A;  2C23 A;  4GNT A;  4ZDR A;  1YWT A;  2C1N A;  4DHQ A;  1A37 A;  2B05 A;  4IHL A;  5D2D A;  4DX0 A;  2O98 A;  3CU8 A;  3U9X A;  3SML A;  4QLI A;  4IEA A;  5EWZ A;  5F74 A;  4O46 A;  2WH0 A;  3LW1 A;  4Y3B A;  2V7D A;  4FL5 A;  5LVZ A;  4DHR A;  3P1N A;  4DHN A;  1O9D A;  3SMK A;  3P1R A;  4DNK A;  2O02 A;  3EFZ A;  4N7Y A;  3UZD A;  3P1S A;  5LU2 A;  3UBW A;  2BTP A;  3AXY C;  2BR9 A;  4DHU A;  4N7G A;  1O9F A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...