4FJ3A

14-3-3 isoform zeta in complex with a diphoyphorylated c-raf peptide
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
229
structure length
220
Chain Sequence
DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELSYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Synergistic binding of the phosphorylated S233- and S259-binding sites of C-RAF to one 14-3-3zeta dimer
pubmed doi rcsb
molecule tags Protein binding/transferase
source organism Homo sapiens
molecule keywords 14-3-3 protein zeta/delta
total genus 97
structure length 220
sequence length 229
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 4fj3A00
4J6SA 1YZ5A 2C1JA 4BG6A 1YWTA 3E6YA 4Y3BA 4DHSA 4O46A 3M51A 4GNTA 4WRQA 4DHRA 2BQ0A 5D3FA 4DAUA 2BTPA 1O9DA 3P1NA 4IEAA 4DHQA 1O9CA 3IQVA 3T0MA 4F7RA 2C63A 5LHOA 5IQPA 2O98A 2BR9A 2O02A 2B05A 3M50A 1A4OA 4Y32A 5LU1A 4E2EA 3P1PA 5EWZA 4FR3A 4IHLA 4Y5IA 5LVZA 2O8PA 3O8IA 2WH0A 5J31A 3LW1A 4ZQ0A 4DNKA 3EFZA 4JC3A 3UZDA 5LU2A 3SP5A 4JDDA 1A37A 3IQUA 3SMNA 1IB1A 3SMLA 5HF3A 5F74A 1O9FA 5EXAA 4DHNA 4HKCA 4DHUA 3SPRA 4DX0A 3MHRA 3UBWA 5BTVA 4FJ3A 4DHOA 3U9XA 1A38A 4DHTA 4DHPA 3RDHA 4QLIA 3CU8A 3UALA 3UX0A 3P1QA 3P1SA 4FL5A 2V7DA 3SMOA 1QJBA 1QJAA 5D3EA 4N7GA 2NPMA 2C23A 4ZDRA 4DHMA 3P1RA 5BY9A 3IQJA 3NKXA 3SMMA 5D2DA 4N7YA 1O9EA 3AXYC 2C1NA 3T0LA 4N84A 4DATA 5LX2A 3SMKA 2C74A 3P1OA
chains in the Genus database with same CATH superfamily
4J6SA 1YZ5A 4QX1A 2C1JA 4BG6A 1YWTA 3E6YA 4Y3BA 3ZHEB 4DHSA 4O46A 3M51A 4GNTA 4WRQA 4DHRA 1W99A 2BQ0A 5D3FA 4DAUA 3I4RA 2BTPA 4W8JA 1O9DA 3P1NA 3EB7A 4IEAA 4DHQA 1O9CA 3IQVA 3T0MA 4F7RA 2C63A 5LHOA 5IQPA 3CQCA 2O98A 2BR9A 2O02A 2B05A 3M50A 1A4OA 4QX0A 4Y32A 5LU1A 4E2EA 4QX2A 3P1PA 5EWZA 4D8MA 4FR3A 4IHLA 4Y5IA 5LVZA 1URJA 2O8PA 3O8IA 2WH0A 5J31A 3LW1A 4ZQ0A 1DLCA 4DNKA 3EFZA 4JC3A 3X0UA 3UZDA 5LU2A 3SP5A 4JDDA 1A37A 3IQUA 3SMNA 1CIYA 1IB1A 3SMLA 5HF3A 5F74A 1O9FA 5EXAA 1JI6A 4DHNA 4HKCA 4DHUA 3SPRA 4DX0A 3MHRA 3UBWA 5BTVA 4FJ3A 4DHOA 4MOAA 3U9XA 4QX3A 1A38A 4DHTA 4DHPA 2C9KA 3RDHA 3CQGA 4QLIA 3CU8A 4ARYA 3UALA 3UX0A 3P1QA 3P1SA 1I5PA 4FL5A 2V7DA 3SMOA 1QJBA 1QJAA 5D3EA 4N7GA 2NPMA 2C23A 4ZDRA 4DHMA 3P1RA 5BY9A 3IQJA 3NKXA 3SMMA 5D2DA 4N7YA 1O9EA 3AXYC 2C1NA 3T0LA 4N84A 4ARXA 4DATA 5LX2A 3SMKA 2C74A 1S2XA 3P1OA
chains in the Genus database with same CATH topology
4J6SA 1YZ5A 2C1JA 4BG6A 1YWTA 3E6YA 4Y3BA 4DHSA 4O46A 3M51A 4GNTA 4WRQA 4DHRA 2BQ0A 5D3FA 4DAUA 2BTPA 1O9DA 3P1NA 4IEAA 4DHQA 1O9CA 3IQVA 3T0MA 4F7RA 2C63A 5LHOA 5IQPA 2O98A 2BR9A 2O02A 2B05A 3M50A 1A4OA 4Y32A 5LU1A 4E2EA 3P1PA 5EWZA 4FR3A 4IHLA 4Y5IA 5LVZA 2O8PA 3O8IA 2WH0A 5J31A 3LW1A 4ZQ0A 4DNKA 3EFZA 4JC3A 3UZDA 5LU2A 3SP5A 4JDDA 1A37A 3IQUA 3SMNA 1IB1A 3SMLA 5HF3A 5F74A 1O9FA 5EXAA 4DHNA 4HKCA 4DHUA 3SPRA 4DX0A 3MHRA 3UBWA 5BTVA 4FJ3A 4DHOA 3U9XA 1A38A 4DHTA 4DHPA 3RDHA 4QLIA 3CU8A 3UALA 3UX0A 3P1QA 3P1SA 4FL5A 2V7DA 3SMOA 1QJBA 1QJAA 5D3EA 4N7GA 2NPMA 2C23A 4ZDRA 4DHMA 3P1RA 5BY9A 3IQJA 3NKXA 3SMMA 5D2DA 4N7YA 1O9EA 3AXYC 2C1NA 3T0LA 4N84A 4DATA 5LX2A 3SMKA 2C74A 3P1OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J6S A;  1YZ5 A;  2C1J A;  4BG6 A;  1YWT A;  3E6Y A;  4Y3B A;  4DHS A;  4O46 A;  3M51 A;  4GNT A;  4WRQ A;  4DHR A;  2BQ0 A;  5D3F A;  4DAU A;  2BTP A;  1O9D A;  3P1N A;  4IEA A;  4DHQ A;  1O9C A;  3IQV A;  3T0M A;  4F7R A;  2C63 A;  5LHO A;  5IQP A;  2O98 A;  2BR9 A;  2O02 A;  2B05 A;  3M50 A;  1A4O A;  4Y32 A;  5LU1 A;  4E2E A;  3P1P A;  5EWZ A;  4FR3 A;  4IHL A;  4Y5I A;  5LVZ A;  2O8P A;  3O8I A;  2WH0 A;  5J31 A;  3LW1 A;  4ZQ0 A;  4DNK A;  3EFZ A;  4JC3 A;  3UZD A;  5LU2 A;  3SP5 A;  4JDD A;  1A37 A;  3IQU A;  3SMN A;  1IB1 A;  3SML A;  5HF3 A;  5F74 A;  1O9F A;  5EXA A;  4DHN A;  4HKC A;  4DHU A;  3SPR A;  4DX0 A;  3MHR A;  3UBW A;  5BTV A;  4FJ3 A;  4DHO A;  3U9X A;  1A38 A;  4DHT A;  4DHP A;  3RDH A;  4QLI A;  3CU8 A;  3UAL A;  3UX0 A;  3P1Q A;  3P1S A;  4FL5 A;  2V7D A;  3SMO A;  1QJB A;  1QJA A;  5D3E A;  4N7G A;  2NPM A;  2C23 A;  4ZDR A;  4DHM A;  3P1R A;  5BY9 A;  3IQJ A;  3NKX A;  3SMM A;  5D2D A;  4N7Y A;  1O9E A;  3AXY C;  2C1N A;  3T0L A;  4N84 A;  4DAT A;  5LX2 A;  3SMK A;  2C74 A;  3P1O A; 
#chains in the Genus database with same CATH topology
 4J6S A;  1YZ5 A;  4QX1 A;  2C1J A;  4BG6 A;  1YWT A;  3E6Y A;  4Y3B A;  3ZHE B;  4DHS A;  4O46 A;  3M51 A;  4GNT A;  4WRQ A;  4DHR A;  1W99 A;  2BQ0 A;  5D3F A;  4DAU A;  3I4R A;  2BTP A;  4W8J A;  1O9D A;  3P1N A;  3EB7 A;  4IEA A;  4DHQ A;  1O9C A;  3IQV A;  3T0M A;  4F7R A;  2C63 A;  5LHO A;  5IQP A;  3CQC A;  2O98 A;  2BR9 A;  2O02 A;  2B05 A;  3M50 A;  1A4O A;  4QX0 A;  4Y32 A;  5LU1 A;  4E2E A;  4QX2 A;  3P1P A;  5EWZ A;  4D8M A;  4FR3 A;  4IHL A;  4Y5I A;  5LVZ A;  1URJ A;  2O8P A;  3O8I A;  2WH0 A;  5J31 A;  3LW1 A;  4ZQ0 A;  1DLC A;  4DNK A;  3EFZ A;  4JC3 A;  3X0U A;  3UZD A;  5LU2 A;  3SP5 A;  4JDD A;  1A37 A;  3IQU A;  3SMN A;  1CIY A;  1IB1 A;  3SML A;  5HF3 A;  5F74 A;  1O9F A;  5EXA A;  1JI6 A;  4DHN A;  4HKC A;  4DHU A;  3SPR A;  4DX0 A;  3MHR A;  3UBW A;  5BTV A;  4FJ3 A;  4DHO A;  4MOA A;  3U9X A;  4QX3 A;  1A38 A;  4DHT A;  4DHP A;  2C9K A;  3RDH A;  3CQG A;  4QLI A;  3CU8 A;  4ARY A;  3UAL A;  3UX0 A;  3P1Q A;  3P1S A;  1I5P A;  4FL5 A;  2V7D A;  3SMO A;  1QJB A;  1QJA A;  5D3E A;  4N7G A;  2NPM A;  2C23 A;  4ZDR A;  4DHM A;  3P1R A;  5BY9 A;  3IQJ A;  3NKX A;  3SMM A;  5D2D A;  4N7Y A;  1O9E A;  3AXY C;  2C1N A;  3T0L A;  4N84 A;  4ARX A;  4DAT A;  5LX2 A;  3SMK A;  2C74 A;  1S2X A;  3P1O A; 
#chains in the Genus database with same CATH homology
 4J6S A;  1YZ5 A;  2C1J A;  4BG6 A;  1YWT A;  3E6Y A;  4Y3B A;  4DHS A;  4O46 A;  3M51 A;  4GNT A;  4WRQ A;  4DHR A;  2BQ0 A;  5D3F A;  4DAU A;  2BTP A;  1O9D A;  3P1N A;  4IEA A;  4DHQ A;  1O9C A;  3IQV A;  3T0M A;  4F7R A;  2C63 A;  5LHO A;  5IQP A;  2O98 A;  2BR9 A;  2O02 A;  2B05 A;  3M50 A;  1A4O A;  4Y32 A;  5LU1 A;  4E2E A;  3P1P A;  5EWZ A;  4FR3 A;  4IHL A;  4Y5I A;  5LVZ A;  2O8P A;  3O8I A;  2WH0 A;  5J31 A;  3LW1 A;  4ZQ0 A;  4DNK A;  3EFZ A;  4JC3 A;  3UZD A;  5LU2 A;  3SP5 A;  4JDD A;  1A37 A;  3IQU A;  3SMN A;  1IB1 A;  3SML A;  5HF3 A;  5F74 A;  1O9F A;  5EXA A;  4DHN A;  4HKC A;  4DHU A;  3SPR A;  4DX0 A;  3MHR A;  3UBW A;  5BTV A;  4FJ3 A;  4DHO A;  3U9X A;  1A38 A;  4DHT A;  4DHP A;  3RDH A;  4QLI A;  3CU8 A;  3UAL A;  3UX0 A;  3P1Q A;  3P1S A;  4FL5 A;  2V7D A;  3SMO A;  1QJB A;  1QJA A;  5D3E A;  4N7G A;  2NPM A;  2C23 A;  4ZDR A;  4DHM A;  3P1R A;  5BY9 A;  3IQJ A;  3NKX A;  3SMM A;  5D2D A;  4N7Y A;  1O9E A;  3AXY C;  2C1N A;  3T0L A;  4N84 A;  4DAT A;  5LX2 A;  3SMK A;  2C74 A;  3P1O A; 
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