3P1QA

Crystal structure of human 14-3-3 sigma c38n/n166h in complex with task-3 peptide and stabilizer fusicoccin a
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
236
structure length
236
Chain Sequence
GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSNEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTHPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface
pubmed doi rcsb
molecule tags Peptide binding protein
source organism Homo sapiens
molecule keywords 14-3-3 protein sigma
total genus 101
structure length 236
sequence length 236
ec nomenclature
pdb deposition date 2010-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 3p1qA00
1O9CA 4FR3A 2C23A 4HKCA 3NKXA 5D3EA 5LHOA 5LVZA 2O02A 4DX0A 3SMKA 1O9FA 4BG6A 5HF3A 5BTVA 4JC3A 2B05A 4QLIA 5BY9A 3UBWA 3P1NA 2C1NA 5D2DA 5EWZA 2WH0A 5LX2A 3SMOA 3T0LA 5IQPA 1A38A 4DHNA 3UZDA 3SMNA 1O9DA 1O9EA 4DHQA 3SMLA 3SP5A 4Y3BA 3SMMA 4DATA 3O8IA 2C63A 5J31A 5LU1A 3UALA 5F74A 3P1OA 4DHTA 3EFZA 4ZDRA 2BQ0A 3P1RA 5D3FA 3E6YA 3SPRA 3LW1A 2C74A 4FJ3A 2O8PA 2BTPA 4DHRA 4DHOA 2V7DA 4IHLA 4GNTA 3T0MA 4WRQA 1A4OA 4DAUA 3AXYC 1YZ5A 1QJAA 1YWTA 2O98A 3M50A 4JDDA 3MHRA 4DNKA 3P1SA 3RDHA 1QJBA 4DHSA 2BR9A 4J6SA 5LU2A 4Y32A 4N7YA 3IQUA 3M51A 4N84A 3IQVA 4O46A 2NPMA 3P1QA 4E2EA 4DHUA 4DHPA 4Y5IA 1IB1A 3U9XA 4IEAA 2C1JA 3UX0A 4FL5A 4ZQ0A 4DHMA 3P1PA 3IQJA 4N7GA 3CU8A 4F7RA 5EXAA 1A37A
chains in the Genus database with same CATH superfamily
1O9CA 4FR3A 2C23A 4MOAA 4HKCA 3NKXA 5D3EA 5LHOA 5LVZA 2O02A 3CQCA 4DX0A 3SMKA 1O9FA 4BG6A 5HF3A 5BTVA 1W99A 4JC3A 2B05A 4QX1A 4QLIA 5BY9A 3UBWA 3P1NA 2C1NA 3X0UA 5D2DA 5EWZA 2WH0A 5LX2A 1I5PA 3SMOA 3T0LA 5IQPA 1A38A 4DHNA 3UZDA 3SMNA 1O9DA 4D8MA 1DLCA 1O9EA 4DHQA 3SMLA 3SP5A 4Y3BA 3SMMA 4DATA 3O8IA 2C63A 5J31A 4QX3A 5LU1A 3UALA 1S2XA 5F74A 1URJA 3P1OA 3EB7A 4DHTA 3EFZA 4ZDRA 2BQ0A 3P1RA 5D3FA 3E6YA 3SPRA 3LW1A 3CQGA 2C74A 4FJ3A 2O8PA 2BTPA 4DHRA 4DHOA 2V7DA 4IHLA 1CIYA 4GNTA 3T0MA 4WRQA 1A4OA 4DAUA 4QX2A 3AXYC 4W8JA 1YZ5A 1QJAA 1YWTA 2O98A 2C9KA 1JI6A 3M50A 4JDDA 3MHRA 4DNKA 3P1SA 3RDHA 4ARYA 1QJBA 4DHSA 2BR9A 3I4RA 4J6SA 5LU2A 4ARXA 4QX0A 4Y32A 4N7YA 3IQUA 3M51A 4N84A 3IQVA 4O46A 2NPMA 3P1QA 4E2EA 4DHUA 4DHPA 4Y5IA 1IB1A 3U9XA 3ZHEB 4IEAA 2C1JA 3UX0A 4FL5A 4ZQ0A 4DHMA 3P1PA 3IQJA 4N7GA 3CU8A 4F7RA 5EXAA 1A37A
chains in the Genus database with same CATH topology
1O9CA 4FR3A 2C23A 4HKCA 3NKXA 5D3EA 5LHOA 5LVZA 2O02A 4DX0A 3SMKA 1O9FA 4BG6A 5HF3A 5BTVA 4JC3A 2B05A 4QLIA 5BY9A 3UBWA 3P1NA 2C1NA 5D2DA 5EWZA 2WH0A 5LX2A 3SMOA 3T0LA 5IQPA 1A38A 4DHNA 3UZDA 3SMNA 1O9DA 1O9EA 4DHQA 3SMLA 3SP5A 4Y3BA 3SMMA 4DATA 3O8IA 2C63A 5J31A 5LU1A 3UALA 5F74A 3P1OA 4DHTA 3EFZA 4ZDRA 2BQ0A 3P1RA 5D3FA 3E6YA 3SPRA 3LW1A 2C74A 4FJ3A 2O8PA 2BTPA 4DHRA 4DHOA 2V7DA 4IHLA 4GNTA 3T0MA 4WRQA 1A4OA 4DAUA 3AXYC 1YZ5A 1QJAA 1YWTA 2O98A 3M50A 4JDDA 3MHRA 4DNKA 3P1SA 3RDHA 1QJBA 4DHSA 2BR9A 4J6SA 5LU2A 4Y32A 4N7YA 3IQUA 3M51A 4N84A 3IQVA 4O46A 2NPMA 3P1QA 4E2EA 4DHUA 4DHPA 4Y5IA 1IB1A 3U9XA 4IEAA 2C1JA 3UX0A 4FL5A 4ZQ0A 4DHMA 3P1PA 3IQJA 4N7GA 3CU8A 4F7RA 5EXAA 1A37A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O9C A;  4FR3 A;  2C23 A;  4HKC A;  3NKX A;  5D3E A;  5LHO A;  5LVZ A;  2O02 A;  4DX0 A;  3SMK A;  1O9F A;  4BG6 A;  5HF3 A;  5BTV A;  4JC3 A;  2B05 A;  4QLI A;  5BY9 A;  3UBW A;  3P1N A;  2C1N A;  5D2D A;  5EWZ A;  2WH0 A;  5LX2 A;  3SMO A;  3T0L A;  5IQP A;  1A38 A;  4DHN A;  3UZD A;  3SMN A;  1O9D A;  1O9E A;  4DHQ A;  3SML A;  3SP5 A;  4Y3B A;  3SMM A;  4DAT A;  3O8I A;  2C63 A;  5J31 A;  5LU1 A;  3UAL A;  5F74 A;  3P1O A;  4DHT A;  3EFZ A;  4ZDR A;  2BQ0 A;  3P1R A;  5D3F A;  3E6Y A;  3SPR A;  3LW1 A;  2C74 A;  4FJ3 A;  2O8P A;  2BTP A;  4DHR A;  4DHO A;  2V7D A;  4IHL A;  4GNT A;  3T0M A;  4WRQ A;  1A4O A;  4DAU A;  3AXY C;  1YZ5 A;  1QJA A;  1YWT A;  2O98 A;  3M50 A;  4JDD A;  3MHR A;  4DNK A;  3P1S A;  3RDH A;  1QJB A;  4DHS A;  2BR9 A;  4J6S A;  5LU2 A;  4Y32 A;  4N7Y A;  3IQU A;  3M51 A;  4N84 A;  3IQV A;  4O46 A;  2NPM A;  3P1Q A;  4E2E A;  4DHU A;  4DHP A;  4Y5I A;  1IB1 A;  3U9X A;  4IEA A;  2C1J A;  3UX0 A;  4FL5 A;  4ZQ0 A;  4DHM A;  3P1P A;  3IQJ A;  4N7G A;  3CU8 A;  4F7R A;  5EXA A;  1A37 A; 
#chains in the Genus database with same CATH topology
 1O9C A;  4FR3 A;  2C23 A;  4MOA A;  4HKC A;  3NKX A;  5D3E A;  5LHO A;  5LVZ A;  2O02 A;  3CQC A;  4DX0 A;  3SMK A;  1O9F A;  4BG6 A;  5HF3 A;  5BTV A;  1W99 A;  4JC3 A;  2B05 A;  4QX1 A;  4QLI A;  5BY9 A;  3UBW A;  3P1N A;  2C1N A;  3X0U A;  5D2D A;  5EWZ A;  2WH0 A;  5LX2 A;  1I5P A;  3SMO A;  3T0L A;  5IQP A;  1A38 A;  4DHN A;  3UZD A;  3SMN A;  1O9D A;  4D8M A;  1DLC A;  1O9E A;  4DHQ A;  3SML A;  3SP5 A;  4Y3B A;  3SMM A;  4DAT A;  3O8I A;  2C63 A;  5J31 A;  4QX3 A;  5LU1 A;  3UAL A;  1S2X A;  5F74 A;  1URJ A;  3P1O A;  3EB7 A;  4DHT A;  3EFZ A;  4ZDR A;  2BQ0 A;  3P1R A;  5D3F A;  3E6Y A;  3SPR A;  3LW1 A;  3CQG A;  2C74 A;  4FJ3 A;  2O8P A;  2BTP A;  4DHR A;  4DHO A;  2V7D A;  4IHL A;  1CIY A;  4GNT A;  3T0M A;  4WRQ A;  1A4O A;  4DAU A;  4QX2 A;  3AXY C;  4W8J A;  1YZ5 A;  1QJA A;  1YWT A;  2O98 A;  2C9K A;  1JI6 A;  3M50 A;  4JDD A;  3MHR A;  4DNK A;  3P1S A;  3RDH A;  4ARY A;  1QJB A;  4DHS A;  2BR9 A;  3I4R A;  4J6S A;  5LU2 A;  4ARX A;  4QX0 A;  4Y32 A;  4N7Y A;  3IQU A;  3M51 A;  4N84 A;  3IQV A;  4O46 A;  2NPM A;  3P1Q A;  4E2E A;  4DHU A;  4DHP A;  4Y5I A;  1IB1 A;  3U9X A;  3ZHE B;  4IEA A;  2C1J A;  3UX0 A;  4FL5 A;  4ZQ0 A;  4DHM A;  3P1P A;  3IQJ A;  4N7G A;  3CU8 A;  4F7R A;  5EXA A;  1A37 A; 
#chains in the Genus database with same CATH homology
 1O9C A;  4FR3 A;  2C23 A;  4HKC A;  3NKX A;  5D3E A;  5LHO A;  5LVZ A;  2O02 A;  4DX0 A;  3SMK A;  1O9F A;  4BG6 A;  5HF3 A;  5BTV A;  4JC3 A;  2B05 A;  4QLI A;  5BY9 A;  3UBW A;  3P1N A;  2C1N A;  5D2D A;  5EWZ A;  2WH0 A;  5LX2 A;  3SMO A;  3T0L A;  5IQP A;  1A38 A;  4DHN A;  3UZD A;  3SMN A;  1O9D A;  1O9E A;  4DHQ A;  3SML A;  3SP5 A;  4Y3B A;  3SMM A;  4DAT A;  3O8I A;  2C63 A;  5J31 A;  5LU1 A;  3UAL A;  5F74 A;  3P1O A;  4DHT A;  3EFZ A;  4ZDR A;  2BQ0 A;  3P1R A;  5D3F A;  3E6Y A;  3SPR A;  3LW1 A;  2C74 A;  4FJ3 A;  2O8P A;  2BTP A;  4DHR A;  4DHO A;  2V7D A;  4IHL A;  4GNT A;  3T0M A;  4WRQ A;  1A4O A;  4DAU A;  3AXY C;  1YZ5 A;  1QJA A;  1YWT A;  2O98 A;  3M50 A;  4JDD A;  3MHR A;  4DNK A;  3P1S A;  3RDH A;  1QJB A;  4DHS A;  2BR9 A;  4J6S A;  5LU2 A;  4Y32 A;  4N7Y A;  3IQU A;  3M51 A;  4N84 A;  3IQV A;  4O46 A;  2NPM A;  3P1Q A;  4E2E A;  4DHU A;  4DHP A;  4Y5I A;  1IB1 A;  3U9X A;  4IEA A;  2C1J A;  3UX0 A;  4FL5 A;  4ZQ0 A;  4DHM A;  3P1P A;  3IQJ A;  4N7G A;  3CU8 A;  4F7R A;  5EXA A;  1A37 A; 
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